[User]
Which numbered sense of "alone" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=isolated from others | examples=could be alone in a crowded room; was alone with her thoughts
2. definition=lacking companions or companionship | synonyms=lone, lonely, solitary | examples=he was alone when we met him; she is alone much of the time
3. definition=exclusive of anyone or anything else | synonyms=only | examples=she alone believed him; cannot live by bread alone
4. definition=radically distinctive and without equal | synonyms=unique, unequaled, unequalled, unparalleled | examples=he is alone in the field of microbiology; this theory is altogether alone in its penetration of the problem

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "alone" is used in the provided context, specifically marked with `<t>alone</t>`. The output must be only the number.

2.  **Examine the context:**
    "...Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant..."

3.  **Analyze the phrase "cannot be removed by surgery alone":**
    *   "Surgery alone" means surgery by itself, without other methods (like chemotherapy or radiation).
    *   The meaning is that surgery is not sufficient or exclusive in its action.

4.  **Evaluate the senses of "alone":**

    *   **Sense 1:** definition=isolated from others | examples=could be alone in a crowded room; was alone with her thoughts. (Relates to physical or mental isolation.) -> *Does not fit.*
    *   **Sense 2:** definition=lacking companions or companionship | synonyms=lone, lonely, solitary | examples=he was alone when we met him; she is alone much of the time. (Relates to being by oneself.) -> *Does not fit.*
    *   **Sense 3:** definition=exclusive of anyone or anything else | synonyms=only | examples=she alone believed him; cannot live by bread alone. (Relates to singularity or exclusivity.) -> *Fits perfectly.* "Surgery alone" means "surgery only" or "surgery exclusively."
    *   **Sense 4:** definition=radically distinctive and without equal | synonyms=unique, unequaled, unequalled, unparalleled | examples=he is alone in the field of microbiology; this theory is altogether alone in its penetration of the problem. (Relates to being unmatched.) -> *Does not fit.*

5.  **Conclusion:** The usage "surgery alone" corresponds to Sense 3 (exclusive of anyone or anything else / only).

6.  **Final Output Generation:** Return only the number 3.


attempt_kind: initial

status: success

[User]
Which numbered sense of "spread" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
3. definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
4. definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
5. definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. definition=cover by spreading something over | examples=spread the bread with cheese
10. definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread

finish_reason: stop

role: assistant

reasoning_content:
1.  **Analyze the context:** The word "spread" is used in the phrase: "malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body)".
2.  **Determine the meaning of "spread" in this context:** In the context of cancer, "to spread to other parts of the body" means the cancer cells are moving from the original site to distant sites (metastasizing). This is a process of becoming distributed or propagating throughout the body.
3.  **Examine the senses provided:**
    *   1. distribute or disperse widely (Focuses on intentional distribution, e.g., invaders spreading language).
    *   2. become distributed or widespread (Focuses on the state of becoming widespread, e.g., infection spreading, optimism spreading).
    *   3. spread across or over (Focuses on covering a surface, e.g., oil spot spreading across water).
    *   4. spread out or open from a closed or folded state (Physical action, e.g., opening a map).
    *   5. cause to become widely known (Focuses on information/knowledge).
    *   6. become widely known and passed on (Focuses on rumors/stories).
    *   7. strew or distribute over an area (Physical scattering, e.g., fertilizer).
    *   8. move outward (Physical movement, e.g., soldiers fanning out).
    *   9. cover by spreading something over (Physical action, e.g., spreading bread with cheese).
    *   10. distribute over a surface in a layer (Physical action, e.g., spreading cheese on bread).
4.  **Match the meaning to the senses:** The cancer is *becoming* distributed in other parts of the body. This aligns perfectly with Sense 2: "become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population."
5.  **Select the corresponding number:** The number is 2.

currency: USD

source: unavailable


[User]
Which numbered sense of "likely" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=has a good chance of being the case or of coming about | examples=these services are likely to be available to us all before long; she is likely to forget
2. definition=likely but not certain to be or become true or real | synonyms=probable | examples=a likely result; he foresaw a probable loss
3. definition=expected to become or be; in prospect | synonyms=potential | examples=potential clients
4. definition=within the realm of credibility | examples=not a very likely excuse

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "likely" (marked with `<t></t>`) is used in the provided context. The output must be only the number.

2.  **Analyze the context sentence:** "...and malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body)..."

3.  **Determine the meaning of "likely" in this specific context:**
    *   The context is medical/biological (cancer spread).
    *   "Likely to spread easily" means there is a high probability or strong expectation that the cancer *will* spread.
    *   It refers to a prediction or probability of a future event (spreading).

4.  **Evaluate the provided senses against the determined meaning:**

    *   **Sense 1:** definition=has a good chance of being the case or of coming about | examples=these services are likely to be available to us all before long; she is likely to forget.
        *   *Match?* Yes. "Likely to spread" means it has a good chance of coming about.

    *   **Sense 2:** definition=likely but not certain to be or become true or real | synonyms=probable | examples=a likely result; he foresaw a probable loss.
        *   *Match?* Yes, this is also a strong candidate, as it emphasizes probability without certainty.

    *   **Sense 3:** definition=expected to become or be; in prospect | synonyms=potential | examples=potential clients.
        *   *Match?* No. This sense relates to inherent possibility or future capacity (potential), not probability of an event occurring.

    *   **Sense 4:** definition=within the realm of credibility | examples=not a very likely excuse.
        *   *Match?* No. This sense relates to believability or plausibility.

5.  **Distinguish between Sense 1 and Sense 2 (if necessary):**
    *   Sense 1: "has a good chance of being the case or of coming about." (Focus on high probability/likelihood of occurrence).
    *   Sense 2: "likely but not certain to be or become true or real." (Focus on probability/possibility, often used interchangeably with 'probable').

    In the phrase "is likely to spread easily," the meaning is clearly predictive probability. Both Sense 1 and Sense 2 capture this. However, Sense 1 ("has a good chance of being the case or of coming about") is the most direct and common definition for predicting a future event (spreading) in a scientific/medical context. Sense 2 is slightly more abstract, focusing on the degree of certainty. Given the options, Sense 1 is the most fitting description of the predictive nature of the phrase.

6.  **Final Selection:** Sense 1.

7.  **Format the output:** Return only the number.


[User]
Which numbered sense of "spread" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
3. definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
4. definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
5. definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. definition=cover by spreading something over | examples=spread the bread with cheese
10. definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread

reasoning_content:
1.  **Analyze the context:** The word "spread" is used in the phrase "...and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body)..."
2.  **Determine the meaning of "spread" in this context:** The context is about cancer (malignant). When cancer "spreads" to other parts of the body, it means the cancer cells are propagating or moving from the original site to distant sites (metastasis).
3.  **Evaluate the provided senses against the determined meaning:**
    *   1. distribute or disperse widely (Focuses on objects/ideas being distributed, not biological propagation).
    *   2. become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population (This matches the biological process of disease/cancer spreading/propagating).
    *   3. spread across or over (Focuses on surface coverage, e.g., oil spot).
    *   4. spread out or open from a closed or folded state (Physical action, e.g., opening a map).
    *   5. cause to become widely known (Information dissemination).
    *   6. become widely known and passed on (Rumor/information).
    *   7. strew or distribute over an area (Scattering physical items, e.g., fertilizer).
    *   8. move outward (Physical movement, e.g., soldiers fanning out).
    *   9. cover by spreading something over (Applying a substance).
    *   10. distribute over a surface in a layer (Applying a substance).
4.  **Select the best match:** Sense 2, "become distributed or widespread," with the synonym "propagate," perfectly describes how cancer cells move and multiply in the body.
5.  **Final check:** The context is about cancer spreading to other parts of the body. Sense 2 is the correct fit.


[User]
Which numbered sense of "easily" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=with ease (`easy' is sometimes used informally for `easily') | synonyms=easy | examples=she was easily excited; was easily confused
2. definition=without question | examples=easily the best book she's written
3. definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "easily" (marked with `<t>easily</t>`) is used in the provided context. The output must be only the number.

2.  **Examine the context:**
    "...and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body)..."

3.  **Analyze the specific phrase:** "is likely to spread easily to other parts of the body."

4.  **Determine the meaning of "easily" in this context:**
    *   The context is discussing cancer malignancy and metastasis (spreading).
    *   "Likely to spread easily" implies that the spread is probable, rapid, or highly likely to occur, rather than just meaning "without difficulty" (like moving a box easily).
    *   It suggests a high probability or propensity for the cancer to disseminate.

5.  **Evaluate the provided senses:**

    *   **Sense 1:** definition=with ease | synonyms=easy | examples=she was easily excited; was easily confused. (Focuses on lack of difficulty/effort). *Does not fit the context of high probability of spread.*
    *   **Sense 2:** definition=without question | examples=easily the best book she's written. (Focuses on certainty/superiority). *Does not fit the context of biological probability of spread.*
    *   **Sense 3:** definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster. (Focuses on likelihood/probability). *This perfectly matches the meaning of "is likely to spread easily" in a medical/biological context.*

6.  **Conclusion:** Sense 3 is the correct meaning.

7.  **Format the output:** Return only the number.


[User]
Which numbered sense of "other" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. definition=recently past | examples=the other evening
3. definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "other" (marked with `<t>other</t>`) is used in the provided context. The output must be only the number.

2.  **Analyze the context:**
    The relevant phrase is: "...and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body)..."

3.  **Determine the meaning of "other" in this context:**
    "Other parts of the body" refers to parts of the body that are *not* the primary site of the cancer (the lungs/pleura). It means additional, different, or remaining parts.

4.  **Evaluate the provided senses:**

    *   **Sense 1:** definition=not the same one or ones already mentioned or implied; examples=today isn't any other day; the construction of highways and other public works.
        *   *Match check:* "Other parts of the body" means parts *not* the primary site. This aligns perfectly with "not the same one or ones already mentioned or implied."

    *   **Sense 2:** definition=recently past; examples=the other evening.
        *   *Match check:* No temporal meaning here. (Incorrect)

    *   **Sense 3:** definition=belonging to the distant past; synonyms=early, former; examples=the early inhabitants of Europe; former generations.
        *   *Match check:* No temporal meaning here. (Incorrect)

    *   **Sense 4:** definition=very unusual; different in character or quality from the normal or expected; examples=a strange, other dimension...where his powers seemed to fail.
        *   *Match check:* While "other" can mean different, in the phrase "other parts of the body," it is used in the sense of *additional* or *remaining* parts, not necessarily parts that are unusually different in quality (like a "strange, other dimension"). Sense 1 is a much stronger fit for spatial/additive distinction. (Less accurate/Incorrect)

5.  **Conclusion:** Sense 1 is the correct meaning.

6.  **Format the output:** Return only the number.


[User]
Which numbered sense of "part" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

reasoning_content:
1.  **Analyze the context:** The phrase is "other parts of the body."
2.  **Determine the meaning of "parts" in this context:** The context refers to the physical locations or regions of the human body where cancer has spread (metastasis).
3.  **Examine the senses provided:** I need to find the sense that refers to a physical location or region of a natural object (the body).
4.  **Evaluate relevant senses:**
    *   Sense 1 (component part): Refers to constituent elements (e.g., a component of a machine). Not suitable for body regions.
    *   Sense 2 (less than the whole of a human artifact): Refers to physical sections of an artifact (e.g., the rear part of a house). Not suitable for biological regions.
    *   Sense 3 (a portion of a natural object): Refers to a piece of a natural object (e.g., a piece of granite). While the body is natural, this sense often implies a discrete, separable piece, whereas "parts of the body" refers to anatomical regions.
    *   Sense 5 (the extended spatial location of something): Definition is "the extended spatial location of something," synonyms include "region." Examples include "the farming regions of France; religions in all parts of the world." This perfectly matches the idea of anatomical regions where the disease is located.
    *   Sense 9 (one of the portions into which something is regarded as divided): Refers to divisions (e.g., sections of an exam). Less appropriate than spatial location for biological spread.

5.  **Select the best fit:** Sense 5, "the extended spatial location of something," is the most accurate definition for "parts of the body" when discussing metastasis.

6.  **Final check:** "Other parts of the body" refers to other spatial regions of the body. This aligns with Sense 5.


[User]
Which numbered sense of "body" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. definition=the central message of a communication | examples=the body of the message was short
9. definition=the main mass of a thing
10. definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. definition=the external structure of a vehicle | examples=the body of the car was badly rusted

reasoning_content:
1.  **Analyze the context:** The word is "body" in the phrase "...to other parts of the <t>body</t>". The context is discussing cancer (pleural mesothelioma, non-small cell lung cancer) and how the cancer has spread.
2.  **Determine the meaning of "body" in this context:** When cancer spreads to "other parts of the body," it refers to the physical structure of the organism (the human patient).
3.  **Examine the senses provided:**
    *   1. definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
    *   2. definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
    *   3. definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
    *   4. definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
    *   5. definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
    *   6. definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
    *   7. definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
    *   8. definition=the central message of a communication | examples=the body of the message was short
    *   9. definition=the main mass of a thing
    *   10. definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
    *   11. definition=the external structure of a vehicle | examples=the body of the car was badly rusted
4.  **Match the meaning to the best sense:** The meaning "the entire structure of an organism" perfectly matches Sense 1.
5.  **Final check:** "Cancer has spread to other parts of the body" refers to the physical structure of the human patient. Sense 1 is the correct match.
6.  **Format the output:** Return only the number.


[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (<t>patients</t>) is used in the provided context. The output must be *only* the number.

2.  **Analyze the Context:**
    *   The context discusses the drug Alimta, its use, and its application in treating cancer.
    *   The specific phrase is: "...in <t>patients</t> who have not received chemotherapy... Alimta is used in combination with cisplatin in patients who have not been treated before..."
    *   The "patients" here are the individuals suffering from cancer who are receiving the medical treatment (Alimta/cisplatin).

3.  **Analyze the Senses:**
    *   **Sense 1:** definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly.
    *   **Sense 2:** definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role.

4.  **Match the Context to the Senses:**
    *   The word "patients" in the context refers to the *people* (individuals) who are receiving medical care for cancer.
    *   Sense 1 defines "a person who requires medical care." This is a direct match.
    *   Sense 2 defines a *grammatical/semantic role* (the patient role in a sentence structure, e.g., "The doctor treated the patient"). While the individuals *are* the semantic patients, the usage in the text is referring to the *people* themselves, not the abstract role.

5.  **Conclusion:** Sense 1 is the correct interpretation of "patients" in this medical context.

6.  **Format the Output:** Return only the number.


[User]
Which numbered sense of "medicine" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "medicine" (marked as `<t>medicines</t>`) is used in the provided context. The output must be only the number.

2.  **Analyze the Context:**
    *   The context discusses "Alimta," a powder/solution containing "pemetrexed."
    *   It states Alimta is used to "treat two types of cancer."
    *   It mentions Alimta is used with "cisplatin (another anticancer medicine)."
    *   The specific phrase is: "...patients who have not received chemotherapy (<t>medicines</t> for cancer) before..."

3.  **Determine the Meaning of `<t>medicines</t>` in Context:**
    *   In the phrase "chemotherapy (medicines for cancer)," "medicines" refers to the drugs/substances used to treat the cancer.
    *   The context is discussing specific pharmaceutical agents (Alimta, cisplatin, pemetrexed).

4.  **Evaluate the Senses:**
    *   **Sense 1:** "the branches of medical science that deal with nonsurgical techniques" (Medical specialty). *Incorrect. The context refers to drugs, not fields of study.*
    *   **Sense 2:** "(medicine) something that treats or prevents or alleviates the symptoms of disease" (Medication, medicinal drug). *Correct. Alimta and cisplatin are examples of these substances.*
    *   **Sense 3:** "the learned profession that is mastered by graduate training in a medical school..." (Practice of medicine). *Incorrect. The context refers to the drugs, not the profession.*
    *   **Sense 4:** "punishment for one's actions" (Take your medicine). *Incorrect. This is a figurative/idiomatic use.*

5.  **Conclusion:** The sense used is Sense 2.

6.  **Format the Output:** Return only the number.


[User]
Which numbered sense of "cancer" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. definition=type genus of the family Cancridae | synonyms=genus Cancer

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "cancer" (marked with `<t>cancer</t>`) is used in the provided context. The output must be only the number.

2.  **Examine the context:** The relevant sentence is: "...in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer..."

3.  **Determine the meaning of "cancer" in the context:**
    *   The context discusses "chemotherapy" (medicines used to treat diseases).
    *   It specifically mentions "advanced or metastatic non-small cell lung cancer."
    *   "Cancer" here refers to a malignant disease or tumor.

4.  **Evaluate the senses provided:**
    *   **Sense 1:** definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease. (This matches the medical context.)
    *   **Sense 2:** definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab. (Irrelevant.)
    *   **Sense 3:** definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini. (Irrelevant.)
    *   **Sense 4:** definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab. (Irrelevant.)
    *   **Sense 5:** definition=type genus of the family Cancridae | synonyms=genus Cancer. (Irrelevant.)

5.  **Conclusion:** The sense used is Sense 1.

6.  **Format the output:** Return only the number.


[User]
Which numbered sense of "advanced" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average
2. definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
3. definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
4. definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
5. definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
6. definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
7. definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
8. definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies

reasoning_content:
1.  **Analyze the context:** The word "advanced" appears in the phrase "...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer..."

2.  **Determine the meaning of "advanced" in this specific context:** The context is discussing cancer stages and treatment protocols. "Advanced" here refers to the stage of the cancer (non-small cell lung cancer) or the stage of the disease in the patient.

3.  **Evaluate the senses provided:**

    *   1. farther along in physical or mental development (e.g., skeletal age). (Not applicable to cancer stage.)
    *   2. comparatively late in a course of development (e.g., illness had reached an advanced stage). (Highly relevant. Cancer stages are described as being late/severe in their development.)
    *   3. ahead of the times (e.g., advanced teaching methods). (Not applicable.)
    *   4. at a higher level in training or knowledge or skill (e.g., advanced degree). (Not applicable.)
    *   5. ahead in development; complex or intricate (e.g., advanced technology). (Could potentially apply to complexity, but Sense 2 is more specific to disease progression.)
    *   6. far along in time (e.g., advanced age). (Relates to time, but Sense 2 relates specifically to the *stage* of the disease.)
    *   7. highly developed especially in technology or industry (e.g., advanced societies). (Not applicable.)
    *   8. situated ahead or going before (e.g., an advance party). (Not applicable.)

4.  **Select the best fit:** The phrase "advanced non-small cell lung cancer" refers to cancer that is far along in its progression or development. This matches Sense 2: "comparatively late in a course of development."

5.  **Final check:** The context is medical/oncological. "Advanced cancer" is standard terminology meaning the cancer is severe, widespread, or late-stage. Sense 2 captures this meaning perfectly.


[User]
Which numbered sense of "cell" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=any small compartment | examples=the cells of a honeycomb
2. definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. definition=small room in which a monk or nun lives | synonyms=cubicle
7. definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

reasoning_content:
1.  **Analyze the context:** The word "cell" appears in the phrase "non-small <t>cell</t> lung cancer that is not affecting the squamous cells."
2.  **Determine the meaning of "cell" in this context:** The context is medical/biological (cancer, lung, mesothelioma, cisplatin, chemotherapy). "Cell" refers to a fundamental unit of tissue or an abnormal group of cells (cancer cells).
3.  **Examine the provided senses:**
    *   1. any small compartment (e.g., honeycomb) - Incorrect.
    *   2. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life... - Highly relevant. Cancer is a disease of abnormal cells.
    *   3. a device that delivers an electric current (electric cell) - Incorrect.
    *   4. a small unit serving as part of or as the nucleus of a larger political movement (cadre) - Incorrect.
    *   5. a hand-held mobile radiotelephone (cellular phone) - Incorrect.
    *   6. small room in which a monk or nun lives (cubicle) - Incorrect.
    *   7. a room where a prisoner is kept (jail cell) - Incorrect.
4.  **Match the meaning to the sense number:** The meaning "basic structural and functional unit of all organisms" (Sense 2) perfectly matches the biological context of "lung cancer cells."
5.  **Formulate the final answer:** Return only the number 2.


[User]
Which numbered sense of "affect" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

reasoning_content:
1.  **Analyze the request:** The user wants to identify which numbered sense of the word "affect" (marked as `<t>affecting</t>`) is used in the provided context. The output must be only the number.

2.  **Analyze the context sentence:** "...advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells."

3.  **Determine the meaning of "affecting" in this context:**
    *   The sentence is discussing cancer (a disease/condition) and its relationship to specific cells (squamous cells).
    *   "Affecting the squamous cells" means the cancer is not impacting, influencing, or targeting those specific cells.
    *   It describes a physical or biological action/influence of the cancer on the cells.

4.  **Evaluate the provided senses:**

    *   **Sense 1:** definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me? (General influence/impact)
    *   **Sense 2:** definition=act physically on; have an effect upon | examples=the medicine affects my heart rate (Physical action/biological effect)
    *   **Sense 3:** definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business (Involvement/relevance)
    *   **Sense 4:** definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache (Pretending - *This is clearly incorrect.*)
    *   **Sense 5:** definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd (Emotional/Cognitive impact - *This is clearly incorrect.*)

5.  **Match the context meaning to the senses:**
    *   The cancer is physically acting upon/influencing the cells.
    *   Sense 2: "act physically on; have an effect upon" matches this meaning perfectly (e.g., a disease affecting cells, a medicine affecting heart rate).

6.  **Conclusion:** Sense 2 is the correct sense.

7.  **Format the output:** Return only the number.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "used" (marked with `<t></t>`) is appropriate in the provided context. The output must be *only* the number.

2.  **Analyze the Context:** The context is about a drug (Alimta) and its function.
    *   "Alimta is a powder... It contains the active substance pemetrexed."
    *   "What is Alimta used for?"
    *   "Alimta is used to treat two types of cancer..."
    *   "Alimta is used in combination with cisplatin..."
    *   The final sentence: "Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

3.  **Determine the Meaning of "used" in the Context:** Here, "used" means "applied for a specific purpose" or "employed as a treatment."

4.  **Evaluate the Senses:**

    *   **1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home**
        *   *Match?* Yes. The drug is employed/utilized for the purpose of treating cancer.

    *   **2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely**
        *   *Match?* No. This refers to consumption (like taking medicine), but the sentence structure ("Alimta is used...") refers to its function/purpose, not the act of consumption itself.

    *   **3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions**
        *   *Match?* No. This means depletion.

    *   **4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections**
        *   *Match?* No. This implies leveraging a resource or person for personal gain/advantage.

    *   **5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion**
        *   *Match?* No. This means benefiting from something (e.g., "I availed myself of the discount").

    *   **6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall**
        *   *Match?* No. This is the "used to" structure, indicating past habit.

5.  **Conclusion:** Sense 1 perfectly captures the meaning of "used" when referring to the application or purpose of a medical treatment.

6.  **Final Output Generation:** Return only the number 1.


[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (<t>patients</t>) is used in the provided context. The output must be *only* the number of the correct sense.

2.  **Analyze the Context:**
    *   The context discusses a drug (Alimta) used to treat cancer.
    *   The relevant phrase is: "Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before..."
    *   The word "patients" refers to the people receiving the medical treatment (cancer treatment).

3.  **Analyze the Senses:**
    *   **Sense 1:** definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly.
    *   **Sense 2:** definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role.

4.  **Match the Context to the Senses:**
    *   In the context, "patients" are the *people* receiving medical care (cancer treatment).
    *   Sense 1 defines "a person who requires medical care." This is a direct match.
    *   Sense 2 defines a *grammatical/semantic role* (the patient role in a sentence structure, e.g., "The ball was thrown *by the boy*"). While the people *are* the semantic patient of the action "treating," Sense 1 is the specific *lexical* meaning being used here (the noun referring to the person).

5.  **Conclusion:** Sense 1 is the correct sense.

6.  **Format the Output:** Return only the number.


[User]
Which numbered sense of "treat" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. definition=regard or consider in a specific way | examples=I treated his advances as a joke

reasoning_content:
1.  **Analyze the context:** The sentence is: "Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past."
2.  **Determine the meaning of "treated" in this context:** The context is medical (cancer, chemotherapy, Alimta, cisplatin). "Treated" refers to receiving medical intervention or therapy.
3.  **Examine the senses provided:**
    *   1. interact in a certain way (e.g., treat him with caution) - Incorrect.
    *   2. subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition (e.g., process cheese) - Possible, but usually refers to preparation, not medical care.
    *   3. provide treatment for (synonyms: care for; examples: The doctor treated my broken leg) - This perfectly matches the medical context (receiving medical treatment/care).
    *   4. act on verbally or in some form of artistic expression (e.g., this book deals with incest) - Incorrect.
    *   5. provide with a gift or entertainment (e.g., treated us to the circus) - Incorrect.
    *   6. provide with choice or abundant food or drink (e.g., I'm treating) - Incorrect.
    *   7. engage in negotiations (e.g., treat with the King) - Incorrect.
    *   8. regard or consider in a specific way (e.g., I treated his advances as a joke) - Incorrect.
4.  **Select the best fit:** Sense 3 ("provide treatment for") is the most accurate definition for "treated" when referring to a patient receiving chemotherapy or cancer medication.
5.  **Final check:** "Patients who have not been treated before" means patients who have not received medical treatment before. This aligns with Sense 3.


[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (<t>patients</t>) is used in the provided context. The output must be *only* the number of the correct sense.

2.  **Analyze the Context:**
    *   The context is about the drug Alimta, which is used to treat cancer.
    *   The relevant sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past."
    *   The word "patients" refers to the people receiving the medical treatment (cancer treatment/chemotherapy).

3.  **Analyze the Senses:**
    *   **Sense 1:** definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly.
    *   **Sense 2:** definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role.

4.  **Determine the Correct Sense:**
    *   In the context, "patients" are the *people* receiving medical care (cancer treatment). This matches the definition of Sense 1.
    *   Sense 2 describes a *grammatical/semantic role* (the patient role in a sentence structure), not the actual person.

5.  **Conclusion:** Sense 1 is the correct sense.

6.  **Format the Output:** Return only the number.


[User]
Which numbered sense of "type" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. definition=printed characters | examples=small type is hard to read
5. definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "type" (<t>type</t>) is used in the provided context and return only the corresponding number.

2.  **Examine the Context:**
    *   "...Alimta is used to treat two types of cancer: pleural mesothelioma..." (Sense 1: subdivision/kind)
    *   "...Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past." (The target phrase is "another type of chemotherapy").

3.  **Analyze the Target Phrase ("another type of chemotherapy"):**
    *   Here, "type" refers to a category or kind of chemotherapy (e.g., drug A, drug B, drug C). It is classifying or subdividing the general category "chemotherapy."

4.  **Evaluate the Senses:**

    *   **1. definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?**
        *   *Match:* "Another type of chemotherapy" means another *kind* or *subdivision* of chemotherapy. This is a strong match.

    *   **2. definition=a person of a specified kind... | synonyms=character, eccentric, case | examples=a real character; a strange character**
        *   *Match:* No. It does not refer to a person.

    *   **3. definition=(biology) the taxonomic group...**
        *   *Match:* No. While chemotherapy involves biology, the usage here is general classification, not formal taxonomy (like genus or species).

    *   **4. definition=printed characters | examples=small type is hard to read**
        *   *Match:* No. It does not refer to printing/fonts.

    *   **5. definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character**
        *   *Match:* No. It does not refer to symbols or tokens.

    *   **6. definition=a small metal block bearing a raised character... | examples=he dropped a case of type...**
        *   *Match:* No. It does not refer to printing blocks.

5.  **Conclusion:** The sense used in "another type of chemotherapy" is Sense 1 (a subdivision of a particular kind of thing).

6.  **Final Output Generation:** Return only the number 1.


[User]
Which numbered sense of "past" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Senses:
1. definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. definition=a verb tense that expresses actions or states in the past | synonyms=past tense

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "past" (marked with `<t></t>`) is used in the provided context. The output must be only the number.

2.  **Analyze the Context:**
    The relevant sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>."

3.  **Analyze the Usage of "past" in the Context:**
    The phrase is "in the past." This refers to a time period *before* the current treatment/administration of Alimta. It means "at some point earlier in their medical history."

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
        *   *Match?* Yes. "In the past" refers to a period of time that has already elapsed (i.e., previous treatments).

    *   **Sense 2:** definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
        *   *Match?* No. This sense relates to personal history or reputation (e.g., "his past mistakes"), not a general timeline of medical treatments.

    *   **Sense 3:** definition=a verb tense that expresses actions or states in the past | synonyms=past tense
        *   *Match?* No. The word "past" here is a noun/adverbial phrase ("in the past"), not a grammatical tense.

5.  **Conclusion:** Sense 1 is the correct usage.

6.  **Final Output Generation:** Return only the number 1.


[User]
Which numbered sense of "medicine" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Senses:
1. definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

reasoning_content:
1.  **Analyze the context:** The text discusses "Alimta," "pemetrexed," "cisplatin," "pleural mesothelioma," "cancer," "chemotherapy," and "anticancer medicine." The specific phrase is: "The <t>medicine</t> can only be obtained with a prescription."

2.  **Determine the meaning of "medicine" in the context:** Since Alimta and cisplatin are drugs used to treat cancer, "medicine" here refers to the substance or drug itself.

3.  **Evaluate the senses provided:**
    *   Sense 1: "the branches of medical science that deal with nonsurgical techniques" (Medical specialty). This is incorrect.
    *   Sense 2: "(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug." This perfectly matches the context (Alimta/cisplatin are drugs/medications).
    *   Sense 3: "the learned profession that is mastered by graduate training in a medical school..." (The practice/profession). This is incorrect.
    *   Sense 4: "punishment for one's actions" (Figurative use). This is incorrect.

4.  **Select the correct sense number:** Sense 2 is the correct fit.

5.  **Format the output:** Return only the number.


[User]
Which numbered sense of "only" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Senses:
1. definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. definition=in the final outcome | examples=These news will only make you more upset
5. definition=except that | examples=It was the same story; only this time she came out better
6. definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. definition=as recently as | examples=I spoke to him only an hour ago

reasoning_content:
1.  **Analyze the context:** The sentence is: "The medicine can <t>only</t> be obtained with a prescription."
2.  **Determine the meaning of "only" in this specific sentence:** The sentence means that *the only way* to get the medicine is by having a prescription. No other method (like buying it over the counter) is available.
3.  **Examine the senses provided:**
    *   1. definition=and nothing more | synonyms=merely, simply, just, but (Focuses on simplicity/minimal nature of an action/state).
    *   2. definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone (Focuses on restriction/exclusivity).
    *   3. definition=with nevertheless the final result (Focuses on unexpected outcomes).
    *   4. definition=in the final outcome (Focuses on results).
    *   5. definition=except that (Focuses on exception/contrast).
    *   6. definition=never except when | synonyms=only if, only when (Focuses on necessary conditions/timing).
    *   7. definition=as recently as (Focuses on time).
4.  **Match the meaning to the senses:**
    *   "The medicine can *only* be obtained with a prescription" means that obtaining it *must* happen via a prescription; no other method is allowed. This is a case of exclusivity.
    *   Sense 2 (definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone) perfectly captures this meaning.
5.  **Select the corresponding number:** The correct sense is 2.


[User]
Which numbered sense of "obtain" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Senses:
1. definition=come into possession of | examples=How did you obtain the visa?
2. definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

reasoning_content:
1.  **Analyze the context:** The sentence is "The medicine can only be <t>obtained</t> with a prescription."
2.  **Analyze the word "obtained":** It refers to how the medicine (Alimta) can be acquired.
3.  **Analyze the options (Senses):**
    *   Sense 1: definition=come into possession of | examples=How did you obtain the visa?
    *   Sense 2: definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
    *   Sense 3: definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds
4.  **Match the context to the senses:**
    *   "The medicine can only be obtained with a prescription" means you must acquire/come into possession of the medicine using a prescription.
    *   Sense 1 ("come into possession of") perfectly matches this meaning.
    *   Sense 2 relates to receiving abstract treatments or reviews, which is irrelevant here.
    *   Sense 3 relates to validity or truth, which is irrelevant here.
5.  **Conclusion:** Sense 1 is the correct meaning.


[User]
Which numbered sense of "prescription" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Senses:
1. definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. definition=written instructions for an optician on the lenses for a given person
4. definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

reasoning_content:
1.  **Analyze the context:** The sentence is "The medicine can only be obtained with a <t>prescription</t>." This sentence relates to obtaining a specific drug (Alimta).
2.  **Analyze the target word:** The word is "prescription."
3.  **Evaluate the senses:**
    *   Sense 1: "definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions." (e.g., "prescription for success"). This refers to general rules or advice, not specifically obtaining medicine.
    *   Sense 2: "definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist; synonyms=prescription drug, prescription medicine, ethical drug." This refers to the *status* of the medicine (it is a prescription drug).
    *   Sense 3: "definition=written instructions for an optician on the lenses for a given person." This is specific to eyewear.
    *   Sense 4: "definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient." This refers to the *document* itself (the written order).
4.  **Determine the best fit for the context:** The context says the medicine can only be obtained *with* a prescription. While Sense 4 describes the physical document (the written instructions), Sense 2 describes the *requirement* that the medicine is controlled and requires such instructions to be obtained. In common usage, when someone says "you need a prescription," they are referring to the requirement (Sense 2) or the document (Sense 4).
5.  **Refine the choice based on typical usage and provided definitions:**
    *   If the context were "The doctor wrote a prescription," Sense 4 would be perfect.
    *   Since the context is "The medicine can only be obtained with a prescription," the focus is on the *type* of medicine or the *requirement* for its acquisition.
    *   Sense 2 ("a drug that is available only with written instructions...") captures the meaning of the requirement most broadly and is often used interchangeably with "prescription drug."
    *   Sense 4 ("written instructions... to a druggist...") is the specific document.

6.  **Re-evaluating the relationship between Sense 2 and Sense 4 in the phrase "with a prescription":**
    *   "With a prescription" usually means "with the required written order." This aligns strongly with Sense 4 (the document).
    *   However, Sense 2 defines the *category* of the drug.
    *   In many linguistic models, when the phrase is "obtainable with a prescription," it is classifying the item as a "prescription drug" (Sense 2).

7.  **Final check against the provided examples/synonyms:**
    *   Sense 2 includes the synonym "prescription drug." The context is about obtaining a controlled drug.
    *   Sense 4 is very specific about the *act* of writing the instructions.

8.  **Conclusion:** Both 2 and 4 are related, but Sense 2 provides the most encompassing definition for the *status* of the medicine that requires the document, which is the core meaning in the phrase "can only be obtained with a prescription." However, if we strictly interpret "with a prescription" as needing the physical document, Sense 4 is technically accurate. Given the options, Sense 2 (defining the drug type) is the most common interpretation in this type of general usage context. Let's stick with Sense 2 as it defines the *nature* of the item being obtained. (If Sense 4 were the intended answer, the phrasing might be "with a doctor's prescription.")

9.  *Self-Correction/Refinement:* Let's assume the model is looking for the most precise fit for the phrase "obtainable with a prescription." This phrase refers to the *requirement* (the document). Sense 4 describes the document itself. Sense 2 describes the *category* of the drug. Since the context is about the *process* of obtaining the drug, Sense 4 is the most precise description of what the "prescription" is in this scenario (the written instructions).

10. *Final Decision:* Sense 4 is the most accurate definition of the physical item ("prescription") required to obtain the medicine.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Senses:
1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

reasoning_content:
1.  **Analyze the context:** The question is "How is Alimta <t>used</t>?" The answer describes Alimta's function: "Alimta is used to treat two types of cancer..." and "Alimta is used together with cisplatin (another anticancer medicine)..."
2.  **Determine the meaning of "used" in this context:** Alimta is being employed or applied for a specific purpose (treating cancer).
3.  **Evaluate the senses:**
    *   1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home. (This matches the idea of employing a medicine for a medical purpose.)
    *   2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely. (This refers to the patient consuming the drug, not the drug's function.)
    *   3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions. (This refers to depletion.)
    *   4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections. (This refers to leveraging resources/people.)
    *   5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion. (This refers to the person applying something.)
    *   6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week... (This is a specific grammatical usage, "used to.")
4.  **Match the meaning to the best sense:** The context clearly indicates that Alimta is being employed/applied/utilized for the purpose of treating cancer. This aligns perfectly with Sense 1.
5.  **Final check:** "Alimta is used to treat cancer" = "Alimta is employed for the purpose of treating cancer." (Sense 1).


[User]
Which numbered sense of "only" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Senses:
1. definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. definition=in the final outcome | examples=These news will only make you more upset
5. definition=except that | examples=It was the same story; only this time she came out better
6. definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. definition=as recently as | examples=I spoke to him only an hour ago

reasoning_content:
1.  **Analyze the target word and context:** The target word is "only" (<t>only</t>). The context is: "Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

2.  **Determine the meaning of "only" in this specific sentence:** The sentence restricts the condition under which Alimta should be given. It means that the supervision of a qualified doctor is the *sole* or *exclusive* requirement/condition for administering the drug.

3.  **Evaluate the provided senses against this meaning:**

    *   **Sense 1:** definition=and nothing more | synonyms=merely, simply, just, but | *Focuses on simplicity or minimal nature.* (e.g., "I was merely asking.") This doesn't fit the restrictive, exclusive condition here.
    *   **Sense 2:** definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | *Focuses on exclusivity.* (e.g., "solely," "exclusively"). This perfectly matches the meaning: the drug should *exclusively* be given under the supervision of a qualified doctor, and no other condition is sufficient.
    *   **Sense 3:** definition=with nevertheless the final result | *Focuses on unexpected outcomes.* (e.g., "He arrived only to find...") This is a result/consequence sense. Incorrect.
    *   **Sense 4:** definition=in the final outcome | *Focuses on future results.* (e.g., "These news will only make you more upset.") Incorrect.
    *   **Sense 5:** definition=except that | *Focuses on exception.* (e.g., "only this time she came out better.") This is a concessive sense. Incorrect.
    *   **Sense 6:** definition=never except when | synonyms=only if, only when | *Focuses on necessary conditions.* (e.g., "call me only if your cold gets worse.") This is a strong candidate, as it implies a necessary condition.
    *   **Sense 7:** definition=as recently as | *Focuses on time.* (e.g., "I spoke to him only an hour ago.") Incorrect.

4.  **Distinguish between Sense 2 and Sense 6:**
    *   Sense 6 ("only if/when") emphasizes the *condition* (e.g., "You can go only if it stops raining").
    *   Sense 2 ("exclusively/solely") emphasizes the *scope* or *agent* (e.g., "The decision was solely his").

    In the context: "Alimta should only be given under the supervision of a doctor..."
    *   Interpretation 1 (Sense 6): It should be given *only if* a qualified doctor is supervising it. (Necessary condition).
    *   Interpretation 2 (Sense 2): It should be given *exclusively* under the supervision of a qualified doctor (and not, for example, by a nurse without supervision, or in a non-medical setting). (Exclusivity/Sole agent).

    While both senses overlap, Sense 2 (exclusively/solely) captures the idea that the supervision of a qualified doctor is the *only* acceptable way or agent for the action to take place, which is a very strong fit for regulatory/medical language. Sense 6 is also plausible, but Sense 2 is the most precise fit for the restrictive nature of the requirement ("only be given under...").

5.  **Final check:** "Alimta should *exclusively* be given under the supervision of a doctor..." (Sense 2). This is the best fit.