[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: easily
Target surface form: easily
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=easily%4:02:01:: | definition=with ease (`easy' is sometimes used informally for `easily') | synonyms=easy | examples=she was easily excited; was easily confused
2. sense_key=easily%4:02:06:: | definition=without question | examples=easily the best book she's written
3. sense_key=easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "easily" in the given context.

Context:
"...and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body)..."

Target word: easily

Candidate senses:
1. sense_key=easily%4:02:01:: | definition=with ease | synonyms=easy | examples=she was easily excited; was easily confused
2. sense_key=easily%4:02:06:: | definition=without question | examples=easily the best book she's written
3. sense_key=easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster

Analysis of the context:
The phrase is "is likely to spread easily to other parts of the body".
The context is discussing cancer malignancy, specifically the spread of cancer (metastasis).
"Easily" here modifies the verb "spread" (or the likelihood of spreading). It suggests that the spread is probable or happens without significant resistance.

Evaluation of senses:
1. sense_key=easily%4:02:01 (with ease): This suggests physical ease or lack of difficulty in the action. While cancer spread might be considered "easy" in a biological sense, the phrasing "is likely to spread easily" often leans more towards probability than physical ease of movement.
2. sense_key=easily%4:02:06 (without question): This is too strong for describing the likelihood of cancer spread.
3. sense_key=easily%4:02:05 (indicating high probability; in all likelihood): This sense perfectly matches the meaning required in the context of biological spread ("is likely to spread..."). If cancer is likely to spread easily, it means it has a high probability of doing so.

Conclusion: Sense 3 is the best fit.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "other" in the provided context.

Context snippet: "...and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body)..."

The word "other" is modifying "parts of the body." It refers to body parts that are not the primary site of the cancer (implied by the context of metastasis/spreading).

Let's analyze the candidate senses:

1. **sense_key=other%3:00:00::** | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
    * This sense means "different from what has been mentioned/implied." This fits the context perfectly. The cancer has spread to parts of the body *other than* the primary site.

2. **sense_key=other%5:00:02:past:00** | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
    * This relates to time (past). Not relevant here.

3. **sense_key=other%5:00:00:strange:00** | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail
    * This relates to strangeness or unusualness. While "other" can mean strange, the context here is spatial/locational (parts of the body), not qualitative.

4. **sense_key=other%5:00:00:strange:00** (Wait, there are two senses labeled 5:00:00:strange:00 in the list provided, but I should check the provided list carefully. Let's re-examine the list provided in the prompt.)

Candidate senses provided:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

The context requires "other" to mean "different from the primary site" or "additional/unspecified."

Sense 1: "not the same one or ones already mentioned or implied." This is the best fit for describing metastatic spread to unspecified, non-primary body parts.

Therefore, sense 1 is the correct choice.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: parts
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The sentence is: "Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body)..."
2.  **Identify the target word and its role:** The target word is "parts," referring to "other parts of the body."
3.  **Determine the meaning of "parts" in this context:** Here, "parts" refers to specific locations or regions within the body where the cancer has spread.
4.  **Examine the candidate senses:**
    *   1. something determined in relation to something that includes it (portion, component part). (General component/section)
    *   2. something less than the whole of a human artifact (portion). (Relates to man-made objects)
    *   3. a portion of a natural object (piece). (Relates to natural objects like granite, river)
    *   4. that which concerns a person with regard to a particular role or situation (role/responsibility). (Abstract/role)
    *   5. the extended spatial location of something (region). (Geographical/spatial area)
    *   6. the actions and activities assigned to or required or expected of a person or group (function/role). (Abstract/role)
    *   7. an actor's portrayal of someone in a play (character/role). (Theatrical)
    *   8. assets belonging to or due to or contributed by an individual person or group (share). (Financial)
    *   9. one of the portions into which something is regarded as divided and which together constitute a whole (section/division). (General division)
    *   10. a line of scalp... (Hair parting). (Specific physical feature)
    *   11. the melody carried by a particular voice or instrument (musical part). (Musical)
    *   12. the part played by a person in bringing about a result (contribution/share). (Role/contribution)
5.  **Match the meaning to the best sense:** The context refers to anatomical locations where cancer has spread ("other parts of the body"). This is a spatial/anatomical reference.
    *   Sense 5: "the extended spatial location of something (synonyms=region; examples=the farming regions of France; religions in all parts of the world)." This sense captures the idea of a specific location or region within the body.
    *   Sense 1: "something determined in relation to something that includes it (synonyms=portion, component part, component, constituent)." This is also plausible, as body parts are components, but Sense 5 emphasizes the *location* (spatial extent), which is highly relevant when discussing metastasis (spreading to different regions).

6.  **Refine the choice between 1 and 5:**
    *   If the cancer spreads to the liver, the liver is a *component part* (Sense 1).
    *   If the cancer spreads to the lungs, the lungs are a *region* (Sense 5).
    *   Since the context is about the spread of disease to different areas of the body, the concept of a spatial location or region (Sense 5) is the most precise fit for describing where the cancer has gone.

7.  **Final Selection:** Sense 5.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The sentence is: "Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy..."
2.  **Identify the target word and its function:** The target word is "body." It follows the phrase "to other parts of the body."
3.  **Determine the meaning required by the context:** The context is medical (cancer, chemotherapy, malignant spread). "Spread to other parts of the body" refers to the physical structure of the organism being attacked by the cancer.
4.  **Examine the candidate senses:**
    *   1. `sense_key=body%1:08:00`: "the entire structure of an organism (an animal, plant, or human being)." (Matches the medical context perfectly: cancer spreading through the human organism.)
    *   2. `sense_key=body%1:14:00`: "a group of persons associated by some common tie or occupation..." (Incorrect. Refers to groups of people.)
    *   3. `sense_key=body%1:08:02`: "a natural object consisting of a dead animal or person." (Incorrect. The cancer is spreading to living parts.)
    *   4. `sense_key=body%1:17:00`: "an individual 3-dimensional object that has mass..." (Too general; doesn't capture the biological/organism aspect.)
    *   5. `sense_key=body%1:08:01`: "the body excluding the head and neck and limbs." (Incorrect. Refers specifically to the torso/trunk, but the context refers to *other parts* of the whole organism.)
    *   6. `sense_key=body%1:14:02`: "a collection of particulars considered as a system." (Incorrect. Refers to abstract collections, like a body of law.)
    *   7. `sense_key=body%1:07:00`: "the property of holding together and retaining its shape." (Incorrect. Refers to physical consistency/structure, e.g., dough.)
    *   8. `sense_key=body%1:10:00`: "the central message of a communication." (Incorrect. Refers to text/speech.)
    *   9. `sense_key=body%1:07:01`: "the main mass of a thing." (Too general; doesn't specify an organism.)
    *   10. `sense_key=body%1:06:01`: "a resonating chamber in a musical instrument..." (Incorrect. Musical context.)
    *   11. `sense_key=body%1:06:00`: "the external structure of a vehicle." (Incorrect. Vehicle context.)
5.  **Select the best fit:** Sense 1 ("the entire structure of an organism") is the precise definition required when discussing cancer spreading to "other parts of the body."
6.  **Format the output:** Return the JSON object with the correct sense index.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{
  "sense_index": 1
}
```

content:
```json
{
  "sense_index": 1
}
```

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the word "patients" (plural of "patient") based on the provided context.

Context: "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable... and malignant... in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer..."

Target word: patients

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Analysis:
The context discusses a drug (Alimta) used to treat cancer. The phrase is "in patients who have not received chemotherapy...".
The word "patients" here refers to the people receiving the medical treatment (cancer patients).

Sense 1: "a person who requires medical care". This perfectly matches the usage in the context (people receiving cancer treatment).
Sense 2: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause". This is a grammatical/linguistic concept (the semantic role of a patient), not the meaning of the noun "patient" in this medical context.

Conclusion: Sense 1 is the correct sense.

I need to return the output in the specified JSON format, using the index of the chosen sense.
Sense 1 corresponds to index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicines
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target surface form "medicines" (plural of "medicine") based on the provided context.

Context analysis:
The text discusses "Alimta," a powder used in a solution for infusion. It mentions that Alimta is used to treat two types of cancer (pleural mesothelioma and non-small cell lung cancer).
The phrase in question is: "...in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer..."

The word "medicines" here refers to treatments previously administered to the patients.

Candidate senses analysis:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty. (Refers to a field of study/specialty, e.g., internal medicine. Incorrect.)
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug. (Refers to the substance/drug itself. This fits the context of "chemotherapy medicines" used to treat cancer.)
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine. (Refers to the profession/practice. Incorrect.)
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music. (Idiomatic usage, "face the music." Incorrect.)

Conclusion:
The context clearly indicates that "medicines" refers to drugs or treatments used for cancer. Sense 2, defined as "something that treats or prevents or alleviates the symptoms of disease" and synonymous with "medication" and "medicinal drug," is the correct sense.

The instruction requires returning only a JSON object with the sense index.
Sense 2 corresponds to index 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "cancer" based on the provided context and candidate senses.

Context analysis:
The text discusses a drug (Alimta) used to treat "two types of cancer: pleural mesothelioma (cancer of the lining of the lungs...)" and mentions "anticancer medicine," "chemotherapy (medicines for <t>cancer</t>)," and "advanced or metastatic non-small cell lung cancer."

The usage of "cancer" here is clearly medical, referring to a malignant disease.

Candidate senses analysis:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Matching:
The context refers to a disease treated by chemotherapy and described as "malignant" and "metastatic."
Sense 1 defines "any malignant growth or tumor caused by abnormal and uncontrolled cell division," which perfectly matches the medical context.
Senses 2, 3, 4, and 5 relate to astrology or biology (crabs/genus), which are irrelevant to the context.

Conclusion: Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: advanced
Target surface form: advanced
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=advanced%5:00:00:precocious:00 | definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average
2. sense_key=advanced%5:00:00:late:02 | definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
3. sense_key=advanced%5:00:00:progressive:01 | definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
4. sense_key=advanced%5:00:02:high:02 | definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
5. sense_key=advanced%5:00:00:high-tech:00 | definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
6. sense_key=advanced%5:00:00:late:00 | definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
7. sense_key=advanced%5:00:00:civilized:00 | definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
8. sense_key=advanced%5:00:00:front:00 | definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "advanced" in the given context.

Context:
"...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells."

The word "advanced" modifies "non-small cell lung cancer".

Let's analyze the meaning of "advanced" when applied to a disease or cancer. It typically means the disease is far along in its progression or stage.

Candidate senses:
1. sense_key=advanced%5:00:00:precocious:00 | definition=farther along in physical or mental development | (Relates to development, usually biological/mental, not disease stage)
2. sense_key=advanced%5:00:00:late:02 | definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion (This fits the context of disease progression.)
3. sense_key=advanced%5:00:00:progressive:01 | definition=ahead of the times | synonyms=forward-looking, innovative, modern (This is about ideas/technology, not disease stage.)
4. sense_key=advanced%5:00:02:high:02 | definition=at a higher level in training or knowledge or skill (Relates to skill/knowledge level, not disease stage.)
5. sense_key=advanced%5:00:00:high-tech:00 | definition=ahead in development; complex or intricate (Relates to technology, not disease stage.)
6. sense_key=advanced%5:00:00:late:00 | definition=far along in time | synonyms=ripe (Relates to time/age, less specific to disease stage than sense 2.)
7. sense_key=advanced%5:00:00:civilized:00 | definition=(of societies) highly developed especially in technology or industry (Relates to societal development, not disease stage.)
8. sense_key=advanced%5:00:00:front:00 | definition=situated ahead or going before (Relates to physical location/sequence, not disease stage.)

The context clearly refers to the stage of cancer. "Advanced cancer" means the cancer is in a late or progressed stage.

Sense 2: "comparatively late in a course of development" and the example "the illness had reached an advanced stage" perfectly match the usage of "advanced" when describing cancer.

Therefore, sense_key=advanced%5:00:00:late:02 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The sentence is: "...advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells."
2.  **Identify the target word and its role:** The target word is "cell." It is used in the phrase "non-small cell lung cancer."
3.  **Determine the domain:** The context is medical/biological (cancer, mesothelioma, cisplatin, chemotherapy, lung).
4.  **Examine the candidate senses:**
    *   1. any small compartment (General, structural)
    *   2. (biology) the basic structural and functional unit of all organisms... (Biological unit)
    *   3. a device that delivers an electric current... (Electrochemistry)
    *   4. a small unit serving as part of or as the nucleus of a larger political movement (Political)
    *   5. a hand-held mobile radiotelephone... (Technology/Communication)
    *   6. small room in which a monk or nun lives (Architecture/Religious)
    *   7. a room where a prisoner is kept (Architecture/Legal)
5.  **Match the context to the senses:**
    *   "Lung cancer" involves biological units (cells).
    *   The phrase "non-small cell lung cancer" refers to a specific type of cancer defined by the type of cells involved.
    *   Sense 2, defining the basic structural and functional unit of all organisms, is the precise biological meaning required here.
6.  **Select the best sense:** Sense 2 is the correct fit.
7.  **Format the output:** Create the required JSON object.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "affecting" (the present participle of "affect") based on the provided context.

Context: "...advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells."

Target word: affecting (from the lemma 'affect')

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Analysis of the context:
The sentence discusses cancer treatment (Alimta, cisplatin) and specifies a condition of the cancer: "non-small cell lung cancer that is not affecting the squamous cells."
In a medical context, "affecting the cells" means the cancer is not invading, changing, or impacting those specific cells.

Evaluation of senses:
1. sense_key=affect%2:30:00 (have an effect upon): This is a general sense of influence. This fits the medical context well (the cancer is not having an effect on the cells).
2. sense_key=affect%2:29:00 (act physically on; have an effect upon): This is also a strong candidate, emphasizing a physical interaction, which is highly relevant when discussing cancer and cells.
3. sense_key=affect%2:42:00 (connect closely and often incriminatingly): This sense relates to relationships or legal connections (e.g., "affects your business"). This is irrelevant here.
4. sense_key=affect%2:32:00 (make believe with the intent to deceive): This is clearly irrelevant (feigning).
5. sense_key=affect%2:37:00 (have an emotional or cognitive impact upon): This is clearly irrelevant (emotional/cognitive impact).

Comparing Sense 1 and Sense 2:
Sense 1: "have an effect upon" (General influence)
Sense 2: "act physically on; have an effect upon" (Physical action/impact)

Since the context is biological/medical (cancer and cells), the interaction is physical (the cancer cells are either invading or not invading the squamous cells). Sense 2, which specifies "act physically on," is the most precise fit for describing a biological process where one entity (cancer) interacts with another (cells).

Therefore, sense_key=affect%2:29:00 is the best choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "used" (past tense of "use") based on the provided context.

Context analysis:
The text discusses a medicine called Alimta, which is used to treat specific types of cancer (pleural mesothelioma, non-small cell lung cancer).
The key sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."
The question asked earlier in the text is: "What is Alimta used for?" (Answer: to treat cancer).

The meaning of "used" here is related to the application or function of the medicine—it is employed for a specific therapeutic purpose.

Candidate senses analysis:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
    * This sense aligns perfectly with applying a medicine (Alimta) for a specific purpose (treating cancer).

2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
    * While medicine is consumed, the context focuses on its *purpose* (treatment), not just the act of consumption/habituation. Sense 1 is more precise for therapeutic application.

3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
    * This means depletion, which is incorrect here.

4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
    * This relates to leveraging resources or people for personal gain, which is not the context.

5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
    * This means utilizing a method or resource (like applying a principle), but Sense 1 (employ for a particular purpose) is a better fit for the application of a drug.

6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
    * This refers to past habits ("used to"), which is incorrect.

Conclusion: Sense 1, "put into service; make work or employ for a particular purpose," is the best fit, as Alimta is employed/utilized for the purpose of treating cancer.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{
  "sense_index": 1
}
```

reasoning_content:
1.  **Analyze the target word and context:**
    *   Target lemma: patient
    *   Target surface form: patients
    *   Context: "Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."
    *   The context discusses a cancer drug (Alimta) and its use in people who have specific medical conditions (cancer, unresectable, malignant, etc.) and treatment histories (not treated before, received chemotherapy in the past).

2.  **Analyze the candidate senses:**
    *   **Sense 1 (patient%1:18:00):**
        *   Definition: a person who requires medical care.
        *   Example: the number of emergency patients has grown rapidly.
        *   Relevance: This aligns perfectly with the context. The people receiving Alimta are individuals requiring medical care for cancer.
    *   **Sense 2 (patient%1:10:00):**
        *   Definition: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.
        *   Synonyms: affected role, patient role.
        *   Relevance: This is a grammatical/semantic role definition (like 'theme' or 'recipient'), not a definition of the noun referring to a person. It is highly unlikely to be the intended sense in this medical context.

3.  **Determine the best sense:**
    *   Sense 1 is the clear and direct fit. The word refers to the individuals receiving the medical treatment.

4.  **Format the output:**
    *   The instruction requires returning only a JSON object with the sense index.
    *   Sense 1 corresponds to index 1. (Wait, the prompt uses `sense_key=patient%1:18:00` and `sense_key=patient%1:10:00`. I must map the chosen sense to the index provided in the prompt structure, which is implicitly 1 and 2 based on the listing order.)
    *   Sense 1 is the first candidate listed.

5.  **Final check:** Choose Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treated
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "treated" (past tense of "treat") based on the provided context.

Context: "Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past."

The context is medical, discussing cancer treatment (Alimta, cisplatin, chemotherapy). The phrase "have not been treated before" refers to the patients' prior medical history regarding cancer therapy.

Let's analyze the candidate senses:

1. **sense_key=treat%2:41:00::** | definition=interact in a certain way | synonyms=handle, do by. (Too general, doesn't fit the medical context of prior therapy.)
2. **sense_key=treat%2:30:01::** | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process. (This is about subjecting something to a process, which is close, but sense 3 is more specific to medical care.)
3. **sense_key=treat%2:29:00::** | definition=provide treatment for | synonyms=care for. (This sense focuses on the action of *giving* treatment. When used passively, "have not been treated before," it means they have not *received* medical treatment for the condition.)
4. **sense_key=treat%2:32:00::** | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address. (Irrelevant - literary/academic context.)
5. **sense_key=treat%2:40:00::** | definition=provide with a gift or entertainment. (Irrelevant - social context.)
6. **sense_key=treat%2:34:00::** | definition=provide with choice or abundant food or drink | synonyms=regale. (Irrelevant - dining context.)
7. **sense_key=treat%2:32:03::** | definition=engage in negotiations in order to reach an agreement. (Irrelevant - political/business context.)
8. **sense_key=treat%2:31:00::** | definition=regard or consider in a specific way. (Irrelevant - psychological/perceptual context.)

Revisiting Sense 3:
**sense_key=treat%2:29:00::** | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims.

In the context "patients who have not been treated before," the passive construction implies that the patients have not *received* the medical intervention (treatment/care) for their condition. Sense 3, while defined actively ("provide treatment for"), is the core sense related to medical care and therapy, which is the domain of the text. The concept of receiving medical treatment aligns perfectly with this sense.

Sense 2 ("subject to a process or treatment") is also plausible, but Sense 3 ("provide treatment for") is the standard, high-level definition used when discussing medical intervention (chemotherapy, cancer treatment).

Therefore, Sense 3 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the target word and context:**
    *   Target surface form: "patients" (plural of "patient").
    *   Context: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past."
    *   The context is about cancer treatment (Alimta, cisplatin, chemotherapy, cancer types). The word "patients" refers to the people receiving the medical treatment.

2.  **Analyze the candidate senses:**
    *   **Sense 1 (patient%1:18:00):**
        *   Definition: "a person who requires medical care."
        *   Example: "the number of emergency patients has grown rapidly."
        *   Relevance: This perfectly matches the usage in the context (people receiving chemotherapy/cancer treatment).
    *   **Sense 2 (patient%1:10:00):**
        *   Definition: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause."
        *   Synonyms: "affected role, patient role."
        *   Relevance: This is a grammatical/linguistic concept (the semantic role of a patient), not the referent (the person) in the medical context.

3.  **Determine the best sense:**
    *   The context clearly uses "patients" to refer to individuals receiving medical care for cancer.
    *   Sense 1 defines "a person who requires medical care."
    *   Sense 2 defines a grammatical/semantic role.
    *   Sense 1 is the correct interpretation.

4.  **Format the output:**
    *   The instruction requires returning only a JSON object with the sense index.
    *   Sense 1 corresponds to index 1. (Wait, the prompt uses numbered lists for candidates, so Sense 1 is index 1).

5.  **Final check:**
    *   Target: patients
    *   Context: Medical treatment for cancer.
    *   Best sense: Person requiring medical care (Sense 1).
    *   Output format: JSON.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
Thinking Process:

1.  **Analyze the Context:** The sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past."
2.  **Identify the Target Word:** The target word is "type".
3.  **Analyze the Collocates/Grammar:** "another [type] of chemotherapy". Here, "type" modifies "chemotherapy" and is used as a noun meaning a category or kind.
4.  **Examine Candidate Senses:**

    *   1. `type%1:09:00`: "a subdivision of a particular kind of thing". (Matches the idea of a category/kind of chemotherapy).
    *   2. `type%1:18:00`: "a person of a specified kind". (Irrelevant; chemotherapy is not a person).
    *   3. `type%1:14:01`: "(biology) the taxonomic group whose characteristics are used to define the next higher taxon". (Too specific/technical, though related to classification, sense 1 is broader and fits the medical context better).
    *   4. `type%1:10:01`: "printed characters". (Irrelevant).
    *   5. `type%1:10:00`: "all of the tokens of the same symbol". (Irrelevant).
    *   6. `type%1:06:00`: "a small metal block bearing a raised character". (Irrelevant).

5.  **Select the Best Sense:** Sense 1, "a subdivision of a particular kind of thing," perfectly captures the meaning of "another type of chemotherapy," where "type" refers to a category or kind of treatment.

6.  **Format the Output:** Return the JSON object with the correct sense index. (Sense 1 corresponds to index 1).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{
  "sense_index": 1
}
```

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the target word "past" in the given context.

Context: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription."

Target word: "past"

Candidate senses:
1. `past%1:28:00`: definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. `past%1:28:01`: definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. `past%1:10:00`: definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Analysis of the context:
The phrase is "in the past". This refers to a time period when the patient received chemotherapy.

Evaluation of senses:
1. `past%1:28:00` (the time that has elapsed): This fits perfectly. "In the past" refers to a time that has already occurred.
2. `past%1:28:01` (an earlier period in someone's life, often secret): This sense usually relates to personal history or reputation (e.g., "her past mistakes"). While chemotherapy history is part of a patient's life, the usage here is purely temporal ("in the past" = previously/before now), not focused on a hidden or problematic period.
3. `past%1:10:00` (a verb tense): This is grammatical/linguistic and does not fit the usage "in the past" as a noun phrase referring to time.

Comparing Sense 1 and Sense 2:
Sense 1 ("the time that has elapsed") is the standard temporal meaning of "in the past."
Sense 2 ("an earlier period in someone's life") is too narrow and implies a specific biographical context (like scandal or secrets), which is not the case here.

Therefore, Sense 1 is the best fit.

Wait, I need to check the provided sense keys and ensure I select the correct index based on the provided list structure.

Candidate senses:
1. sense_key=past%1:28:00
2. sense_key=past%1:28:01
3. sense_key=past%1:10:00

The best sense is `past%1:28:00`, which corresponds to index 1.

Wait, the instructions ask me to return the JSON object with the sense index. Let me re-read the provided list structure to ensure I map correctly.

1. sense_key=past%1:28:00
2. sense_key=past%1:28:01
3. sense_key=past%1:10:00

The best sense is the first one (index 1).

Let's double-check the provided example structure in the prompt:
"Return only a JSON object exactly like {"sense_index": 3}."

If I choose sense 1, the output should be `{"sense_index": 1}`.

Final check: Context is "in the past" (referring to a time before the current treatment). Sense 1 is "the time that has elapsed." This is correct.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "medicine" in the provided context.

Context: "It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?"

Target word: "medicine" (the final instance).

Let's analyze the context surrounding the target word:
"...in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used?"

Key clues:
1. The context discusses cancer treatment, chemotherapy, and specific drugs (Alimta, cisplatin, pemetrexed).
2. The phrase "can only be obtained with a prescription" strongly suggests a pharmaceutical product (a drug/medication).

Now let's evaluate the candidate senses:

1. `sense_key=medicine%1:09:00`: "the branches of medical science that deal with nonsurgical techniques" (medical specialty). This refers to the field of study, not the drug itself. (e.g., "He studied medicine.")
2. `sense_key=medicine%1:06:00`: "(medicine) something that treats or prevents or alleviates the symptoms of disease" (medication/drug). This fits perfectly with the context of cancer treatment and prescription requirements.
3. `sense_key=medicine%1:04:00`: "the learned profession that is mastered by graduate training in a medical school..." (practice of medicine). This refers to the profession/field of study. (e.g., "He studied medicine at Harvard.")
4. `sense_key=medicine%1:04:02`: "punishment for one's actions" (idiomatic use, e.g., "face the music"). This is irrelevant.

The target word "medicine" refers to the specific drug (Alimta or a related treatment) that requires a prescription. This aligns with sense 2: "something that treats or prevents or alleviates the symptoms of disease."

Therefore, sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "only" in the given context.

Context: "The medicine can <t>only</t> be obtained with a prescription."

Target word: only

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Analysis of the context:
"The medicine can only be obtained with a prescription."
This sentence means that obtaining the medicine is restricted to one method: having a prescription. It implies exclusivity. It cannot be obtained without a prescription, nor can it be obtained by other means (like over-the-counter).

Matching the context to the senses:

1. sense_key=only%4:02:02 (merely, simply, just): This suggests limitation in scope or degree, but often emphasizes simplicity. "It is merely a matter of time." While related to limitation, "exclusively" fits better here.
2. sense_key=only%4:02:01 (entirely, exclusively, solely, alone): This sense means "without any others being included or involved." This perfectly matches the meaning of "only" in "can only be obtained with a prescription," meaning *exclusively* with a prescription.
3. sense_key=only%4:02:00 (with nevertheless the final result): This sense relates to unexpected outcomes ("won only to lose"). Not applicable.
4. sense_key=only%4:02:04 (in the final outcome): This sense relates to future consequences ("will only make you more upset"). Not applicable.
5. sense_key=only%4:02:06 (except that): This is a concessive meaning ("only this time"). Not applicable.
6. sense_key=only%4:02:03 (never except when): This is a conditional meaning ("only if"). While the sentence implies a condition (if you have a prescription), the core meaning is about the *exclusive* method of obtaining it, which is better captured by sense 2 (exclusively/solely).
7. sense_key=only%4:02:05 (as recently as): This is temporal. Not applicable.

Conclusion: Sense 2, defined by synonyms like "exclusively" and "solely," is the best fit for "The medicine can only be obtained with a prescription."

The required output format is a JSON object with the sense index.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: obtain
Target surface form: obtained
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "obtained" (past participle of "obtain") in the given context.

Context: "The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?"

Target word: obtained
Candidate senses:
1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

Analysis:
The sentence is "The medicine can only be obtained with a prescription."
The context is about a specific medicine (Alimta).
"Obtained with a prescription" means acquiring or getting the medicine legally through a doctor's order.

Let's evaluate the senses:
1. **sense_key=obtain%2:40:00:: definition=come into possession of**: This perfectly matches the meaning of acquiring a physical item (medicine) using a required document (prescription).
2. **sense_key=obtain%2:30:00:: definition=receive a specified treatment (abstract)**: This sense relates to abstract concepts or treatments (like receiving an interpretation or a review). While medicine is a treatment, the focus here is on the *act of acquisition* (getting it from a pharmacy), not the *effect* of the treatment.
3. **sense_key=obtain%2:42:00:: definition=be valid, applicable, or true**: This sense relates to validity or truth (e.g., a theory holding true). This is irrelevant to acquiring medicine.

Conclusion: Sense 1, "come into possession of," is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prescription
Target surface form: prescription
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
4. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "prescription" in the given context.

Context: "The medicine can only be obtained with a <t>prescription</t>."

Target lemma: prescription
Target surface form: prescription

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | synonyms=... | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
4. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

Analysis:
The context mentions "The medicine can only be obtained with a prescription."
The subject is "medicine" (Alimta, an anticancer drug).
When obtaining medicine, a prescription refers to the authorization or written order from a healthcare professional.

Let's evaluate the senses:
1. sense_key=prescription%1:10:00: This is about general directions or rules (e.g., "prescription for success"). This doesn't fit the context of obtaining medicine.
2. sense_key=prescription%1:06:00: This defines a *drug* that requires instructions ("a drug that is available only with written instructions..."). While related to the concept, the context uses "prescription" as the *thing* needed to obtain the medicine, not the medicine itself.
3. sense_key=prescription%1:10:02: This is specific to opticians and lenses. Irrelevant.
4. sense_key=prescription%1:10:01: This defines "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient." This perfectly matches the function of a prescription when obtaining medicine (Alimta).

Comparing 4 and 2:
Sense 2 defines a *type of drug* (a prescription drug).
Sense 4 defines the *document/instructions* (the prescription) that allows the drug to be issued.
The context says "obtained with a prescription," meaning the document/authorization is required. Therefore, Sense 4 is the most accurate fit for the usage in the sentence.

The best sense is 4.