[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: face
Target surface form: faced
Context:
A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby <t>faced</t>. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Candidate senses:
1. sense_key=face%2:32:00:: | definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes
2. sense_key=face%2:33:00:: | definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring
3. sense_key=face%2:42:00:: | definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond
4. sense_key=face%2:42:02:: | definition=be opposite | examples=the facing page; the two sofas face each other
5. sense_key=face%2:38:00:: | definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now
6. sense_key=face%2:32:03:: | definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions
7. sense_key=face%2:39:04:: | definition=turn so as to expose the face | examples=face a playing card
8. sense_key=face%2:35:00:: | definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket
9. sense_key=face%2:35:01:: | definition=cover the front or surface of | examples=The building was faced with beautiful stones

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "faced" in the given context.
The target lemma is "face".
The context sentence is: "A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."

The word "faced" here is used in the structure "faced no more risk". This implies encountering, being subject to, or dealing with a potential threat or danger.

Let's analyze the candidate senses:

1. **sense_key=face%2:32:00:: | definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes**
   * This sense means to confront or deal with a difficult situation or threat. "Faced no more risk" fits perfectly with "faced no more threat/danger."

2. **sense_key=face%2:33:00:: | definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring**
   * This relates to opposition in a competition. Not applicable here.

3. **sense_key=face%2:42:00:: | definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond**
   * Directional sense. Not applicable.

4. **sense_key=face%2:42:02:: | definition=be opposite | examples=the facing page; the two sofas face each other**
   * Positional sense. Not applicable.

5. **sense_key=face%2:38:00:: | definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now**
   * Action of turning. Not applicable.

6. **sense_key=face%2:32:03:: | definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions**
   * This sense is about presenting evidence or accusations to someone. While related to confrontation, the context ("faced no more risk") is about the *existence* of a threat, not being presented with evidence of a threat. Sense 1 is broader and fits the abstract concept of risk/danger better.

7. **sense_key=face%2:39:04:: | definition=turn so as to expose the face | examples=face a playing card**
   * Action of exposing. Not applicable.

8. **sense_key=face%2:35:00:: | definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket**
   * Tailoring/design sense. Not applicable.

9. **sense_key=face%2:35:01:: | definition=cover the front or surface of | examples=The building was faced with beautiful stones**
   * Covering sense. Not applicable.

The context "faced no more risk" strongly aligns with Sense 1: "deal with (something unpleasant) head on," where "risk" is the unpleasant thing being dealt with/encountered.

Therefore, Sense 1 is the best fit.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: using
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test <t>using</t> new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "using" (a present participle of "use") based on the provided context and candidate senses for "use".

Context:
"A test <t>using</t> new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."

Target word: using

Analysis of the context:
The test is described as "using new 'genetic probes'". This means the test employs or utilizes these probes as a method or tool to achieve its purpose (detecting the gene).

Analysis of candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Matching the context to the senses:
The test *employs* or *utilizes* the genetic probes.

Sense 1: "put into service; make work or employ for a particular purpose or for its inherent or natural purpose." This perfectly matches the idea of a test employing probes as a tool for diagnosis.

Sense 2: Consumption/habituation. Incorrect.
Sense 3: Consume fully/expend. Incorrect.
Sense 4: Achieve an end by using to one's advantage (often implies strategic use of resources/people). While related, Sense 1 is a more direct fit for instrumental use (tool/method).
Sense 5: Avail oneself to (applying a principle/practice). Incorrect.
Sense 6: Habitual past action. Incorrect.

Sense 1 is the best fit.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: new
Target surface form: new
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using <t>new</t> "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=new%3:00:00:: | definition=not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered | examples=a new law; new cars
2. sense_key=new%5:00:00:original:00 | definition=original and of a kind not seen before | synonyms=fresh, novel | examples=the computer produced a completely novel proof of a well-known theorem
3. sense_key=new%5:00:00:inexperienced:00 | definition=lacking training or experience | synonyms=raw | examples=the new men were eager to fight; raw recruits
4. sense_key=new%5:00:00:unprecedented:00 | definition=having no previous example or precedent or parallel | synonyms=unexampled | examples=a time of unexampled prosperity
5. sense_key=new%5:00:00:other:00 | definition=other than the former one(s); different | examples=they now have a new leaders; my new car is four years old but has only 15,000 miles on it
6. sense_key=new%3:00:09:: | definition=unaffected by use or exposure | examples=it looks like new
7. sense_key=new%5:00:02:original:00 | definition=(of a new kind or fashion) gratuitously new | synonyms=newfangled | examples=newfangled ideas; she buys all these new-fangled machines and never uses them
8. sense_key=new%5:00:02:late:01 | definition=in use after medieval times | examples=New Eqyptian was the language of the 18th to 21st dynasties
9. sense_key=new%5:00:01:late:01 | definition=used of a living language; being the current stage in its development | synonyms=Modern | examples=Modern English; New Hebrew is Israeli Hebrew
10. sense_key=new%5:00:00:early:02 | definition=(of crops) harvested at an early stage of development; before complete maturity | synonyms=young | examples=new potatoes; young corn
11. sense_key=new%5:00:00:unaccustomed:00 | definition=unfamiliar | examples=new experiences; experiences new to him

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The target word is "new". It appears in the sentence: "A test using <t>new</t> "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."

2.  **Analyze the surrounding text/topic:** The passage discusses emerging genetic tests, predictive cancer diagnosis, and the findings of these tests ("new findings"). The specific instance of "new genetic probes" refers to the tools/tests themselves.

3.  **Examine the candidate senses:**

    *   1. `new%3:00:00`: not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered. (e.g., a new law; new cars). *This fits the idea of recently developed/discovered tests.*
    *   2. `new%5:00:00:original:00`: original and of a kind not seen before. (e.g., novel proof). *Possible, but perhaps too strong; 'recently developed' is more likely.*
    *   3. `new%5:00:00:inexperienced:00`: lacking training or experience. (e.g., raw recruits). *Does not fit probes.*
    *   4. `new%5:00:00:unprecedented:00`: having no previous example or precedent or parallel. (e.g., unexampled prosperity). *Possible, but 'recently developed' is a better fit for a specific test.*
    *   5. `new%5:00:00:other:00`: other than the former one(s); different. (e.g., my new car). *Does not fit the technical context.*
    *   6. `new%3:00:09`: unaffected by use or exposure. (e.g., looks like new). *Does not fit probes.*
    *   7. `new%5:00:02:original:00`: (of a new kind or fashion) gratuitously new. (e.g., newfangled ideas). *Implies novelty for its own sake, less likely for scientific tools.*
    *   8. `new%5:00:02:late:01`: in use after medieval times. (e.g., New Eqyptian). *Historical/linguistic, irrelevant.*
    *   9. `new%5:00:01:late:01`: used of a living language; being the current stage in its development. (e.g., Modern English). *Linguistic, irrelevant.*
    *   10. `new%5:00:00:early:02`: (of crops) harvested at an early stage of development. (e.g., new potatoes). *Agricultural, irrelevant.*
    *   11. `new%5:00:00:unaccustomed:00`: unfamiliar. (e.g., new experiences). *Possible, but sense 1 captures the development aspect better.*

4.  **Select the best fit:** The context describes "genetic probes" that are being used in a medical/scientific context, following a discussion of "emerging genetic tests." The probes are therefore recently developed or acquired. Sense 1, "not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered," is the most accurate description of newly developed scientific tools.

5.  **Final Check:** "A test using new genetic probes" means probes that are recently created or introduced into use. Sense 1 matches this perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: genetic
Target surface form: genetic
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "<t>genetic</t> probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=genetic%5:00:00:inheritable:00 | definition=occurring among members of a family usually by heredity | synonyms=familial, hereditary, inherited, transmitted, transmissible | examples=an inherited disease; familial traits
2. sense_key=genetic%3:01:02:: | definition=of or relating to or produced by or being a gene | synonyms=genic, genetical | examples=genic combinations; genetic code
3. sense_key=genetic%3:01:01:: | definition=pertaining to or referring to origin | examples=genetic history reconstructs the origins of a literary work
4. sense_key=genetic%3:01:00:: | definition=of or relating to the science of genetics | synonyms=genetical | examples=genetic research

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
Thinking Process:

1.  **Analyze the Target Word and Context:**
    *   Target word: "genetic"
    *   Context sentence: "A test using new 'genetic' probes showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."
    *   Surrounding context: The passage discusses cancer susceptibility, inherited risk (retinoblastoma), damaged genes, and tests used to determine inheritance.

2.  **Analyze the Candidates:**

    *   **Candidate 1 (sense_key=genetic%5:00:00:inheritable:00):**
        *   Definition: occurring among members of a family usually by heredity.
        *   Synonyms: familial, hereditary, inherited, transmitted, transmissible.
        *   Relevance: High. The context is entirely about inherited risk and genes passed down through families.
        *   Example: an inherited disease; familial traits.

    *   **Candidate 2 (sense_key=genetic%3:01:02):**
        *   Definition: of or relating to or produced by or being a gene.
        *   Synonyms: genic, genetical.
        *   Relevance: High. The context explicitly mentions "damaged gene" and "retinoblastoma supressor gene." The probes are testing the gene itself.
        *   Example: genic combinations; genetic code.

    *   **Candidate 3 (sense_key=genetic%3:01:01):**
        *   Definition: pertaining to or referring to origin.
        *   Relevance: Low. While genes relate to origin, the specific usage ("genetic probes" testing inheritance) is more technical/biological than historical/origin-based.
        *   Example: genetic history reconstructs the origins of a literary work.

    *   **Candidate 4 (sense_key=genetic%3:01:00):**
        *   Definition: of or relating to the science of genetics.
        *   Synonyms: genetical.
        *   Relevance: Medium. While the test is *part* of genetics, the word "genetic" here modifies "probes," referring to the nature of the probes (i.e., related to genes), not the field of study itself.
        *   Example: genetic research.

3.  **Determine the Best Fit:**

    *   The phrase is "genetic probes." Probes are tools used in molecular biology to detect specific sequences. These sequences are genes.
    *   Candidate 2 ("of or relating to or produced by or being a gene") perfectly describes the nature of a gene-specific probe.
    *   Candidate 1 ("occurring among members of a family usually by heredity") describes the *outcome* or *phenomenon* (the risk), but Candidate 2 describes the *nature* of the tool ("probes") used to measure that phenomenon.
    *   In the specific phrase "genetic probes," the meaning is technical: probes designed to interact with genetic material (DNA/genes). This aligns most closely with Candidate 2.

4.  **Final Selection:** Candidate 2. (Note: The instructions require returning the index number, not the key).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: show
Target surface form: showed
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "<t>showed</t> that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=show%2:39:02:: | definition=give an exhibition of to an interested audience | synonyms=demo, exhibit, present, demonstrate | examples=She shows her dogs frequently; We will demo the new software in Washington
2. sense_key=show%2:31:00:: | definition=establish the validity of something, as by an example, explanation or experiment | synonyms=prove, demonstrate, establish, shew | examples=The experiment demonstrated the instability of the compound; The mathematician showed the validity of the conjecture
3. sense_key=show%2:32:00:: | definition=provide evidence for | synonyms=testify, bear witness, prove, evidence | examples=The blood test showed that he was the father; Her behavior testified to her incompetence
4. sense_key=show%2:39:00:: | definition=make visible or noticeable | examples=She showed her talent for cooking; Show me your etchings, please
5. sense_key=show%2:36:00:: | definition=show in, or as in, a picture | synonyms=picture, depict, render | examples=This scene depicts country life; the face of the child is rendered with much tenderness in this painting
6. sense_key=show%2:32:02:: | definition=give expression to | synonyms=express, evince | examples=She showed her disappointment
7. sense_key=show%2:32:01:: | definition=indicate a place, direction, person, or thing; either spatially or figuratively | synonyms=indicate, point, designate | examples=I showed the customer the glove section; He pointed to the empty parking space
8. sense_key=show%2:39:01:: | definition=be or become visible or noticeable | synonyms=show up | examples=His good upbringing really shows; The dirty side will show
9. sense_key=show%2:32:04:: | definition=indicate a certain reading; of gauges and instruments | synonyms=read, register, record | examples=The thermometer showed thirteen degrees below zero; The gauge read `empty'
10. sense_key=show%2:32:03:: | definition=give evidence of, as of records | examples=The diary shows his distress that evening
11. sense_key=show%2:38:00:: | definition=take (someone) to their seats, as in theaters or auditoriums | synonyms=usher | examples=The usher showed us to our seats
12. sense_key=show%2:33:00:: | definition=finish third or better in a horse or dog race | examples=he bet $2 on number six to show

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The sentence is: "A test using new 'genetic probes' showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."
2.  **Identify the target word and its role:** The target word is "showed" (past tense of "show"). It is used in relation to a "test" and "genetic probes."
3.  **Determine the meaning in context:** The test *produced a result* or *indicated* a specific finding (that Will did not inherit the damaged gene). The function of "showed" here is to convey evidence or a finding derived from the test.
4.  **Examine the candidate senses:**
    *   1. give an exhibition of... (Incorrect - not an exhibition)
    *   2. establish the validity of something... (Possible, but perhaps too strong. The test established a *fact* about his genes.)
    *   3. provide evidence for (Highly relevant. The test provided evidence that he was not at risk.)
    *   4. make visible or noticeable (Incorrect - not about visibility in a general sense)
    *   5. show in, or as in, a picture (Incorrect - not visual representation)
    *   6. give expression to (Incorrect - not emotional expression)
    *   7. indicate a place, direction, person, or thing... (Possible, but usually spatial/directional. Here it's about a finding.)
    *   8. be or become visible or noticeable (Incorrect - this is an intransitive sense, the test is transitive.)
    *   9. indicate a certain reading; of gauges and instruments (Relevant, as tests/probes give readings, but sense 3 is broader and fits the scientific context better.)
    *   10. give evidence of, as of records (Very relevant, similar to sense 3.)
    *   11. take (someone) to their seats... (Incorrect - unrelated)
    *   12. finish third or better... (Incorrect - unrelated)
5.  **Compare the best candidates (3, 9, 10):**
    *   Sense 9 (indicate a certain reading): Fits the mechanism (test/probes give a reading), but sense 3/10 captures the *meaning* of the result (the finding of no risk).
    *   Sense 10 (give evidence of, as of records): Very close to sense 3.
    *   Sense 3 (provide evidence for): This is the most general and accurate description of what a scientific test does when it yields a result—it provides evidence. The test provided evidence *for* the conclusion (that he was safe).

6.  **Final Selection:** Sense 3 ("provide evidence for") is the most precise fit for a scientific test yielding a definitive finding about a biological state.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: little
Target surface form: little
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that <t>little</t> Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=little%3:00:01:: | definition=limited or below average in number or quantity or magnitude or extent | synonyms=small | examples=a little dining room; a little house
2. sense_key=little%3:00:03:: | definition=(quantifier used with mass nouns) small in quantity or degree; not much or almost none or (with `a') at least some | synonyms=slight | examples=little rain fell in May; gave it little thought
3. sense_key=little%5:00:00:young:00 | definition=(of children and animals) young, immature | synonyms=small | examples=what a big little boy you are; small children
4. sense_key=little%5:00:00:unimportant:00 | definition=(informal) small and of little importance | synonyms=fiddling, footling, lilliputian, niggling, piddling, piffling | examples=a fiddling sum of money; a footling gesture
5. sense_key=little%5:00:00:soft:04 | definition=(of a voice) faint | synonyms=small | examples=a little voice; a still small voice
6. sense_key=little%3:00:00:: | definition=low in stature; not tall | synonyms=short | examples=he was short and stocky; short in stature
7. sense_key=little%5:00:00:lowercase:00 | definition=lowercase | synonyms=minuscule, small | examples=little a; small a
8. sense_key=little%5:00:00:emotional:00 | definition=small in a way that arouses feelings (of tenderness or its opposite depending on the context) | examples=a nice little job; bless your little heart

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "little" in the given context.

Context: "A test using new "genetic probes "showed that <t>little</t> Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."

Target word: little

Analysis of the context:
The sentence structure is "showed that little Will Quinlan had not inherited...".
"Will Quinlan" is a proper name (a person's name).
When "little" precedes a person's name, it often functions as a term of endearment or indicates youth/small stature, though in this specific context, given the preceding discussion about a baby/child ("the Quinlan baby"), it likely refers to his age or size.

Analysis of candidate senses:
1. sense_key=little%3:00:01:: | definition=limited or below average in number or quantity or magnitude or extent | synonyms=small | examples=a little dining room; a little house (Relates to quantity/size, but usually applied to things, not names in this manner.)
2. sense_key=little%3:00:03:: | definition=(quantifier used with mass nouns) small in quantity or degree; not much or almost none or (with `a') at least some | synonyms=slight | examples=little rain fell in May; gave it little thought (Quantifier, not applicable here.)
3. sense_key=little%5:00:00:young:00 | definition=(of children and animals) young, immature | synonyms=small | examples=what a big little boy you are; small children (This sense relates to youth, which fits the context of a child named Will Quinlan.)
4. sense_key=little%5:00:00:unimportant:00 | definition=(informal) small and of little importance | synonyms=fiddling, footling, lilliputian, niggling, piddling, piffling | examples=a fiddling sum of money; a footling gesture (Not applicable.)
5. sense_key=little%5:00:00:soft:04 | definition=(of a voice) faint | synonyms=small | examples=a little voice; a still small voice (Not applicable.)
6. sense_key=little%3:00:00:: | definition=low in stature; not tall | synonyms=short | examples=he was short and stocky; short in stature (Relates to stature, which is possible, but sense 3 covers youth/smallness of children more broadly.)
7. sense_key=little%5:00:00:lowercase:00 | definition=lowercase | synonyms=minuscule, small | examples=little a; small a (Not applicable.)
8. sense_key=little%5:00:00:emotional:00 | definition=small in a way that arouses feelings (of tenderness or its opposite depending on the context) | examples=a nice little job; bless your little heart (This is a term of endearment, which is plausible, but sense 3, focusing on youth/smallness of children, is a more direct fit for describing a child.)

Comparison:
The context refers to Will Quinlan, who is a child mentioned in a story about a rare cancer risk.
Sense 3: (of children and animals) young, immature. This perfectly describes a young child.
Sense 6: low in stature; not tall. This is possible, but Sense 3 is broader and more likely when referring to a child in this narrative context.
Sense 8: emotional/term of endearment. While possible, Sense 3 captures the inherent meaning of "little" when applied to a child in a medical/familial context.

I choose Sense 3 as the best fit, as it specifically addresses the meaning of "little" when applied to children, implying youth or smallness, which is consistent with the narrative.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: inherit
Target surface form: inherited
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not <t>inherited</t> a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=inherit%2:40:00:: | definition=obtain from someone after their death | examples=I inherited a castle from my French grandparents
2. sense_key=inherit%2:40:02:: | definition=receive from a predecessor | examples=The new chairman inherited many problems from the previous chair
3. sense_key=inherit%2:40:01:: | definition=receive by genetic transmission | examples=I inherited my good eyesight from my mother

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the word "inherited" (target lemma: inherit) based on the provided context.

Context snippet: "A test using new "genetic probes "showed that little Will Quinlan had not <t>inherited</t> a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer."

Candidate senses:
1. sense_key=inherit%2:40:00:: | definition=obtain from someone after their death | examples=I inherited a castle from my French grandparents (Focus: death/estate)
2. sense_key=inherit%2:40:02:: | definition=receive from a predecessor | examples=The new chairman inherited many problems from the previous chair (Focus: position/role)
3. sense_key=inherit%2:40:01:: | definition=receive by genetic transmission | examples=I inherited my good eyesight from my mother (Focus: genes/biology)

Analysis:
The context explicitly mentions "a damaged retinoblastoma supressor gene." The act of receiving a gene is a biological process, specifically genetic transmission.

*   Sense 1 (obtain after death): Irrelevant. The context is about genes, not property after death.
*   Sense 2 (receive from a predecessor): Irrelevant. While genes are passed down, this sense refers to roles or objects (like a chairman inheriting problems).
*   Sense 3 (receive by genetic transmission): Highly relevant. The context is about inheriting a "damaged... gene."

Conclusion: Sense 3 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: damaged
Target surface form: damaged
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a <t>damaged</t> retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=damaged%3:00:00:: | definition=harmed or injured or spoiled | examples=I won't buy damaged goods; the storm left a wake of badly damaged buildings
2. sense_key=damaged%5:00:00:disreputable:00 | definition=being unjustly brought into disrepute | synonyms=discredited | examples=a discredited politician; her damaged reputation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{
"sense_index": 1
}
```

content:
```json
{
"sense_index": 1
}
```

reasoning_content:
1.  **Analyze the target word and context:**
    *   Target word: "damaged"
    *   Context sentence: "Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby."
    *   The word "damaged" modifies "gene."
    *   The context links the "damaged gene" to the loss of an eye due to a rare tumor (retinoblastoma).

2.  **Analyze the candidate senses:**
    *   **Sense 1 (damaged%3:00:00):** Definition = harmed or injured or spoiled. Examples = "I won't buy damaged goods; the storm left a wake of badly damaged buildings."
    *   **Sense 2 (damaged%5:00:00:disreputable:00):** Definition = being unjustly brought into disrepute. Synonyms = discredited. Examples = "a discredited politician; her damaged reputation."

3.  **Evaluate the senses against the context:**
    *   The context refers to a *gene* that is associated with a severe physical outcome (losing an eye to cancer).
    *   Sense 2 (disreputable/reputation) is clearly irrelevant. A gene is not "disreputable."
    *   Sense 1 (harmed or injured or spoiled) fits the biological/medical context. A "damaged gene" implies a gene that is faulty, mutated, or compromised, leading to harm (the cancer/eye loss). This aligns perfectly with the definition of being "harmed or injured."

4.  **Select the best sense:**
    *   Sense 1 is the correct choice.

5.  **Format the output:**
    *   The instruction requires returning only a JSON object with the sense index.
    *   Sense 1 corresponds to index 1. (Wait, the prompt uses numbered lists for candidates, so I must use the index provided in the prompt structure, which is 1 and 2).

    *   Candidate 1 = sense_key=damaged%3:00:00
    *   Candidate 2 = sense_key=damaged%5:00:00:disreputable:00

    *   The best sense is Candidate 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: face
Target surface form: faced
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, <t>faced</t> no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=face%2:32:00:: | definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes
2. sense_key=face%2:33:00:: | definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring
3. sense_key=face%2:42:00:: | definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond
4. sense_key=face%2:42:02:: | definition=be opposite | examples=the facing page; the two sofas face each other
5. sense_key=face%2:38:00:: | definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now
6. sense_key=face%2:32:03:: | definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions
7. sense_key=face%2:39:04:: | definition=turn so as to expose the face | examples=face a playing card
8. sense_key=face%2:35:00:: | definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket
9. sense_key=face%2:35:01:: | definition=cover the front or surface of | examples=The building was faced with beautiful stones

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "faced" in the given context.
The target lemma is "face", and the surface form is "faced".

Context snippet:
"...it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, <t>faced</t> no more risk than other children of developing the rare cancer."

The word "faced" here is used in the structure "faced no more risk". This implies encountering, experiencing, or being subject to a risk.

Let's analyze the candidate senses:

1. sense_key=face%2:32:00:: | definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes
    * This sense means to confront or deal with something difficult. "Faced no more risk" fits this meaning: the baby did not have to deal with the risk.

2. sense_key=face%2:33:00:: | definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring
    * This is about opposition/competition. Not relevant here.

3. sense_key=face%2:42:00:: | definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond
    * This is about direction. Not relevant here.

4. sense_key=face%2:42:02:: | definition=be opposite | examples=the facing page; the two sofas face each other
    * This is about physical opposition. Not relevant here.

5. sense_key=face%2:38:00:: | definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now
    * This is about turning/orientation. Not relevant here.

6. sense_key=face%2:32:03:: | definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions
    * This is about presenting something (like evidence) to someone. While related to confrontation, the context is about experiencing a risk, not being presented with evidence.

7. sense_key=face%2:39:04:: | definition=turn so as to expose the face | examples=face a playing card
    * This is about exposure/turning. Not relevant here.

8. sense_key=face%2:35:00:: | definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket
    * This is about tailoring/covering an edge. Not relevant here.

9. sense_key=face%2:35:01:: | definition=cover the front or surface of | examples=The building was faced with beautiful stones
    * This is about covering a surface. Not relevant here.

Comparing Sense 1 and Sense 6:
Sense 1 (32:00): deal with (something unpleasant) head on. Example: "He faced the terrible consequences of his mistakes."
Sense 6 (32:03): present somebody with something, usually to accuse or criticize. Example: "He was faced with all the evidence..."

The context is: "...therefore, faced no more risk..."
This means the baby did not have to deal with the risk. This aligns perfectly with Sense 1: "deal with (something unpleasant) head on."

Sense 6 implies an external agent presenting something to the subject (e.g., "He was faced with evidence"). Here, the risk is the thing being encountered, and the subject (the baby) is the one experiencing/dealing with it.

Therefore, Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: more
Target surface form: more
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no <t>more</t> risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=more%3:00:01:: | definition=(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree | synonyms=more than | examples=more land; more support
2. sense_key=more%3:00:02:: | definition=(comparative of `many' used with count nouns) quantifier meaning greater in number | examples=a hall with more seats; we have no more bananas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "more" in the given context.

Context: "A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no <t>more</t> risk than other children of developing the rare cancer."

Target word: "more"

Candidate senses:
1. sense_key=more%3:00:01:: | definition=(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree | synonyms=more than | examples=more land; more support
2. sense_key=more%3:00:02:: | definition=(comparative of `many' used with count nouns) quantifier meaning greater in number | examples=a hall with more seats; we have no more bananas

Analysis of the context:
The phrase is "no more risk than other children".
"Risk" is being quantified. Risk is generally treated as a mass noun (an abstract concept/amount of danger).
The structure "no more X than Y" is a comparative structure indicating equality (i.e., the risk is the same).

Evaluating the senses:
Sense 1: (comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree.
"Risk" is a mass noun. The structure "no more risk than" fits the usage of a comparative quantifier for mass nouns.

Sense 2: (comparative of `many' used with count nouns) quantifier meaning greater in number.
"Risk" is not a count noun. This sense is inappropriate.

Conclusion: Sense 1 is the best fit because "risk" is a mass noun, and the usage is comparative ("no more... than").


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: risk
Target surface form: risk
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more <t>risk</t> than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=risk%1:26:00:: | definition=a source of danger; a possibility of incurring loss or misfortune | synonyms=hazard, jeopardy, peril, endangerment | examples=drinking alcohol is a health hazard
2. sense_key=risk%1:04:00:: | definition=a venture undertaken without regard to possible loss or injury | synonyms=peril, danger | examples=he saw the rewards but not the risks of crime; there was a danger he would do the wrong thing
3. sense_key=risk%1:07:02:: | definition=the probability of becoming infected given that exposure to an infectious agent has occurred | synonyms=risk of infection
4. sense_key=risk%1:07:01:: | definition=the probability of being exposed to an infectious agent | synonyms=risk of exposure

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "risk" in the provided context.
The context is about genetic testing for retinoblastoma, a rare eye cancer.
The specific sentence containing the target word is: "A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more <t>risk</t> than other children of developing the rare cancer."

Let's analyze the context surrounding "risk":
The context discusses the probability of a child developing retinoblastoma based on genetic inheritance.
The phrase is "faced no more risk than other children of developing the rare cancer."
This implies a comparison of probability or likelihood of developing the cancer.

Now let's examine the candidate senses:

1. **sense_key=risk%1:26:00::** | definition=a source of danger; a possibility of incurring loss or misfortune | synonyms=hazard, jeopardy, peril, endangerment | examples=drinking alcohol is a health hazard
    * This is a general sense of danger/possibility of misfortune. It fits the general idea, but is it the most precise fit given the medical/probabilistic context?

2. **sense_key=risk%1:04:00::** | definition=a venture undertaken without regard to possible loss or injury | synonyms=peril, danger | examples=he saw the rewards but not the risks of crime; there was a danger he would do the wrong thing
    * This refers to taking a gamble or undertaking a dangerous action. This does not fit the context of a child's genetic predisposition.

3. **sense_key=risk%1:07:02::** | definition=the probability of becoming infected given that exposure to an infectious agent has occurred | synonyms=risk of infection
    * This is a specific probabilistic sense related to infection. While the context is about cancer (not infection), the core concept is probability of developing a condition.

4. **sense_key=risk%1:07:01::** | definition=the probability of being exposed to an infectious agent | synonyms=risk of exposure
    * This is also a specific probabilistic sense related to infection/exposure. This doesn't fit the context of genetic predisposition to cancer.

Revisiting the context: "faced no more risk than other children of developing the rare cancer."
The test determined that Will Quinlan did not have the damaged gene, meaning his chance (probability) of developing the cancer is the same as the general population's chance.

Sense 1 (a source of danger/possibility of misfortune) is broad and covers the idea of "possibility of developing the cancer."
Sense 3 (the probability of becoming infected given that exposure to an infectious agent has occurred) is highly specific to infectious agents.

However, in medical and genetic contexts, "risk" is often used synonymously with "probability of developing a condition."

Let's compare Sense 1 and the general concept of probability.
Sense 1: "a source of danger; a possibility of incurring loss or misfortune."
The context is about the *possibility* of incurring the misfortune (developing cancer).

If I look at the structure of the candidates, Sense 3 and 4 are highly specialized (infectious agents). Sense 2 is about action/venture. Sense 1 is the most general definition of risk as a possibility of negative outcome.

In the sentence, "faced no more risk than other children of developing the rare cancer," "risk" functions as the likelihood or probability of developing the cancer.

While Sense 1 is the most general fit for "possibility of misfortune," the phrasing in the candidates suggests that the intended distinction might be between general danger (Sense 1) and specific probability (Sense 3/4). Since the context is purely about probability of a genetic condition, the probabilistic nature is key.

If I must choose the *best* fit among the given options, and recognizing that the provided senses might be limited:
Sense 1 captures the essence of "possibility of misfortune" (developing cancer).
Sense 3 captures "probability," but restricts it to "infection."

Given that the context is about the *likelihood* of a negative health outcome (cancer), Sense 1, which defines risk as "a possibility of incurring loss or misfortune," is the most accurate conceptual match, even if the specific medical context leans heavily on probability. The term "possibility of incurring loss or misfortune" perfectly describes the chance of developing a fatal or serious disease.

Let's confirm the choice:
Context: Chance of developing cancer.
Sense 1: Possibility of incurring loss or misfortune. (Match)
Sense 3: Probability of becoming infected. (Mismatch - cancer vs infection)

Therefore, Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than <t>other</t> children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "other" in the given context.
The context is: "A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than <t>other</t> children of developing the rare cancer."

The target word is "other".

Let's analyze the context surrounding "other":
"...faced no more risk than other children of developing the rare cancer."
Here, "other children" refers to children who are not Will, but who are part of the general group of children mentioned (i.e., children of the Quinlan couple, or children in general who might be at risk). The phrase "no more risk than other children" means the risk level is comparable to the risk level of other children.

Now let's examine the candidate senses:

1. **sense_key=other%3:00:00::** | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
   * This sense means 'different from the ones mentioned'. This fits the context perfectly. Will's risk is no more than the risk of *other* (i.e., different) children.

2. **sense_key=other%5:00:02:past:00** | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
   * This relates to time (past). Not relevant here.

3. **sense_key=other%5:00:00:strange:00** | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail
   * This relates to strangeness/unusualness. While related to difference, it doesn't capture the sense of 'remaining members of a group' as well as sense 1.

4. **sense_key=other%5:00:00:past:00** | definition=recently past | examples=the other evening
   * This relates to time (recent past). Not relevant here.

The context requires "other" to mean "the remaining members of the group, excluding the one being discussed (Will)". This aligns precisely with sense 1: "not the same one or ones already mentioned or implied."

Therefore, sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: child
Target surface form: children
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other <t>children</t> of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=child%1:18:00:: | definition=a young person of either sex | synonyms=kid, youngster, minor, shaver, nipper, small fry | examples=she writes books for children; they're just kids
2. sense_key=child%1:18:01:: | definition=a human offspring (son or daughter) of any age | synonyms=kid | examples=they had three children; they were able to send their kids to college
3. sense_key=child%1:18:06:: | definition=an immature childish person | synonyms=baby | examples=he remained a child in practical matters as long as he lived; stop being a baby!
4. sense_key=child%1:18:07:: | definition=a member of a clan or tribe | examples=the children of Israel

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "children" (plural of "child") based on the provided context.

Context analysis:
The text discusses genetic tests, cancer susceptibility (retinoblastoma), and a couple (Bill and Bonnie Quinlan).
The relevant sentence is: "A test using new 'genetic probes 'showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other <t>children</t> of developing the rare cancer."

The word "children" here refers to the offspring of the couple, specifically those who are potentially at risk for retinoblastoma, comparing Will Quinlan's risk to that of his siblings or other offspring.

Candidate senses:
1. sense_key=child%1:18:00:: | definition=a young person of either sex | synonyms=kid, youngster, minor, shaver, nipper, small fry | examples=she writes books for children; they're just kids
2. sense_key=child%1:18:01:: | definition=a human offspring (son or daughter) of any age | synonyms=kid | examples=they had three children; they were able to send their kids to college
3. sense_key=child%1:18:06:: | definition=an immature childish person | synonyms=baby | examples=he remained a child in practical matters as long as he lived; stop being a baby!
4. sense_key=child%1:18:07:: | definition=a member of a clan or tribe | examples=the children of Israel

Evaluation:
*   **Sense 1 (young person):** Too general. While children are young people, the context is specifically about biological offspring and genetic risk.
*   **Sense 2 (human offspring):** This fits perfectly. The context is about the risk faced by the offspring of the Quinlan couple ("Will Quinlan... faced no more risk than other children of developing the rare cancer"). This sense emphasizes the relationship (offspring) rather than just the age.
*   **Sense 3 (immature childish person):** This refers to immaturity or behavior, which is irrelevant here.
*   **Sense 4 (member of a clan/tribe):** This is clearly incorrect in this medical/family context.

Conclusion: Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: develop
Target surface form: developing
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of <t>developing</t> the rare cancer. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=develop%2:36:01:: | definition=make something new, such as a product or a mental or artistic creation | examples=Her company developed a new kind of building material that withstands all kinds of weather; They developed a new technique
2. sense_key=develop%2:36:00:: | definition=work out | synonyms=evolve, germinate | examples=We have developed a new theory of evolution
3. sense_key=develop%2:30:06:: | definition=gain through experience | synonyms=acquire, evolve | examples=I acquired a strong aversion to television; Children must develop a sense of right and wrong
4. sense_key=develop%2:29:00:: | definition=come to have or undergo a change of (physical features and attributes) | synonyms=grow, produce, get, acquire | examples=He grew a beard; The patient developed abdominal pains
5. sense_key=develop%2:42:00:: | definition=come into existence; take on form or shape | synonyms=originate, arise, rise, uprise, spring up, grow | examples=A new religious movement originated in that country; a love that sprang up from friendship
6. sense_key=develop%2:30:04:: | definition=change the use of and make available or usable | synonyms=build up | examples=develop land; The country developed its natural resources
7. sense_key=develop%2:32:00:: | definition=elaborate, as of theories and hypotheses | synonyms=explicate, formulate | examples=Could you develop the ideas in your thesis
8. sense_key=develop%2:31:00:: | definition=create by training and teaching | synonyms=train, prepare, educate | examples=The old master is training world-class violinists; we develop the leaders for the future
9. sense_key=develop%2:30:05:: | definition=be gradually disclosed or unfolded; become manifest | examples=The plot developed slowly
10. sense_key=develop%2:30:00:: | definition=grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment | examples=A flower developed on the branch; The country developed into a mighty superpower
11. sense_key=develop%2:30:09:: | definition=become technologically advanced | synonyms=modernize, modernise | examples=Many countries in Asia are now developing at a very fast pace; Viet Nam is modernizing rapidly
12. sense_key=develop%2:30:01:: | definition=cause to grow and differentiate in ways conforming to its natural development | synonyms=make grow | examples=The perfect climate here develops the grain; He developed a new kind of apple
13. sense_key=develop%2:36:09:: | definition=generate gradually | examples=We must develop more potential customers; develop a market for the new mobile phone
14. sense_key=develop%2:30:10:: | definition=grow emotionally or mature | synonyms=grow | examples=The child developed beautifully in her new kindergarten; When he spent a summer at camp, the boy grew noticeably and no longer showed some of his old adolescent behavior
15. sense_key=develop%2:39:00:: | definition=make visible by means of chemical solutions | examples=Please develop this roll of film for me
16. sense_key=develop%2:35:04:: | definition=superimpose a three-dimensional surface on a plane without stretching, in geometry
17. sense_key=develop%2:33:03:: | definition=move one's pieces into strategically more advantageous positions | examples=Spassky developed quickly
18. sense_key=develop%2:33:02:: | definition=move into a strategically more advantageous position | examples=develop the rook
19. sense_key=develop%2:30:13:: | definition=elaborate by the unfolding of a musical idea and by the working out of the rhythmic and harmonic changes in the theme | examples=develop the melody and change the key
20. sense_key=develop%2:30:03:: | definition=happen | synonyms=break, recrudesce | examples=Report the news as it develops; These political movements recrudesce from time to time
21. sense_key=develop%2:30:12:: | definition=expand in the form of a series | examples=Develop the function in the following form

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:** The sentence is: "A test using new 'genetic probes 'showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of <t>developing</t> the rare cancer."
2.  **Identify the target word and its grammatical role:** Target word is "developing," functioning as a present participle modifying "children."
3.  **Determine the meaning required by the context:** The phrase "children of developing the rare cancer" is slightly awkward grammatically, but contextually, it must mean "children who are developing the rare cancer" or "children who are at risk of developing the rare cancer." Since the preceding clause states Will faced "no more risk than other children," the meaning must relate to the process of the cancer manifesting or progressing in those children.
4.  **Examine the candidate senses for 'develop':**

    *   1. make something new (product/creation) - No.
    *   2. work out (theory/plan) - No.
    *   3. gain through experience (sense of right and wrong) - No.
    *   4. come to have or undergo a change of (physical features/attributes) - Possible, but usually applies to the subject (e.g., the child developing pains). Here, the cancer is developing *in* them.
    *   5. come into existence; take on form or shape (originate) - Possible, but usually refers to the cancer itself, not the children.
    *   6. change the use of and make available or usable (land/resources) - No.
    *   7. elaborate (theories/hypotheses) - No.
    *   8. create by training and teaching (leaders) - No.
    *   9. be gradually disclosed or unfolded; become manifest (plot) - Possible, but usually applied to abstract things.
    *   10. grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment (country) - This sense covers the process of something (like a disease) progressing or manifesting.
    *   11. become technologically advanced - No.
    *   12. cause to grow and differentiate (grain/apple) - No.
    *   13. generate gradually (customers/market) - No.
    *   14. grow emotionally or mature (child) - Refers to the child's maturity, not the cancer's progression.
    *   15. make visible (film) - No.
    *   16. superimpose (geometry) - No.
    *   17. move one's pieces (chess) - No.
    *   18. move into a strategically more advantageous position (chess) - No.
    *   19. elaborate (musical idea) - No.
    *   20. happen (news develops) - Possible, but less precise than describing the disease progression.
    *   21. expand in the form of a series - No.

5.  **Compare the best candidates (4, 5, 9, 10, 20):**
    *   The context is about a *cancer* (a disease) and the *risk* of having it. The disease is the entity that "develops."
    *   Sense 10: "grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment." This perfectly describes how a disease progresses or manifests in a biological system.
    *   Sense 20: "happen." Too general.
    *   Sense 5: "come into existence." Also possible, but Sense 10 captures the ongoing *process* of disease progression better than simple origination.

6.  **Refine the choice:** The phrase "children of developing the rare cancer" implies children who are in the process of the cancer manifesting or progressing. Sense 10, which includes "grow, progress, unfold, or evolve," is the most accurate fit for the biological progression of a disease.

7.  **Final Selection:** Sense 10.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare <t>cancer</t>. "It made our New Year, "says Mr. Quinlan.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "cancer" based on the provided context and candidate senses.

Context analysis:
The text discusses "Emerging genetic tests," "cancer-susceptible individuals," "predictive cancer diagnosis," "retinoblastoma, an eye cancer," "damaged gene," "rare tumor," and "retinoblastoma supressor gene." The overall theme is medical, specifically relating to malignant growths and genetic predisposition.

Target word: "cancer" (in the phrase "developing the rare <t>cancer</t>").

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease (Medical disease)
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab (Astrology/Zodiac)
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini (Astronomy/Zodiac)
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab (Astrology/Zodiac)
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer (Biology/Taxonomy)

Evaluation:
The context is entirely focused on genetic risk, tumors (retinoblastoma), and medical diagnosis.
The phrase "developing the rare cancer" clearly refers to a disease or malignant growth.

Sense 1 (malignant growth/tumor) perfectly matches the medical context.
Senses 2, 3, 4 (astrology/zodiac) are irrelevant.
Sense 5 (genus of crabs) is irrelevant.

Therefore, Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: make
Target surface form: made
Context:
Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It <t>made</t> our New Year, "says Mr. Quinlan. This test was the first to predict reliably whether an individual could expect to develop cancer.

Candidate senses:
1. sense_key=make%2:41:00:: | definition=engage in | synonyms=do | examples=make love, not war; make an effort
2. sense_key=make%2:30:00:: | definition=give certain properties to something | synonyms=get | examples=get someone mad; She made us look silly
3. sense_key=make%2:36:00:: | definition=make or cause to be or to become | synonyms=create | examples=make a mess in one's office; create a furor
4. sense_key=make%2:32:00:: | definition=cause to do; cause to act in a specified manner | synonyms=induce, stimulate, cause, have, get | examples=The ads induced me to buy a VCR; My children finally got me to buy a computer
5. sense_key=make%2:36:08:: | definition=give rise to; cause to happen or occur, not always intentionally | synonyms=cause, do | examples=cause a commotion; make a stir
6. sense_key=make%2:36:01:: | definition=create or manufacture a man-made product | synonyms=produce, create | examples=We produce more cars than we can sell; The company has been making toys for two centuries
7. sense_key=make%2:31:00:: | definition=make, formulate, or derive in the mind | synonyms=draw | examples=I draw a line here; draw a conclusion
8. sense_key=make%2:36:15:: | definition=compel or make somebody or something to act in a certain way | examples=People cannot be made to integrate just by passing a law!; Heat makes you sweat
9. sense_key=make%2:36:09:: | definition=create by artistic means | synonyms=create | examples=create a poem; Schoenberg created twelve-tone music
10. sense_key=make%2:40:01:: | definition=earn on some commercial or business transaction; earn as salary or wages | synonyms=gain, take in, clear, earn, realize, realise | examples=How much do you make a month in your new job?; She earns a lot in her new job
11. sense_key=make%2:36:05:: | definition=create or design, often in a certain way | synonyms=do | examples=Do my room in blue; I did this piece in wood to express my love for the forest
12. sense_key=make%2:42:05:: | definition=to compose or represent: | synonyms=form, constitute | examples=This wall forms the background of the stage setting; The branches made a roof
13. sense_key=make%2:38:02:: | definition=reach a goal, e.g., | synonyms=reach, get to, progress to | examples=make the first team; We made it!
14. sense_key=make%2:42:00:: | definition=be or be capable of being changed or made into | examples=He makes a great host; He will make a fine father
15. sense_key=make%2:36:11:: | definition=make by shaping or bringing together constituents | examples=make a dress; make a cake
16. sense_key=make%2:36:12:: | definition=perform or carry out | examples=make a decision; make a move
17. sense_key=make%2:36:13:: | definition=make by combining materials and parts | synonyms=construct, build | examples=this little pig made his house out of straw; Some eccentric constructed an electric brassiere warmer
18. sense_key=make%2:30:15:: | definition=change from one form into another | examples=make water into wine; make lead into gold
19. sense_key=make%2:29:08:: | definition=act in a certain way so as to acquire | examples=make friends; make enemies
20. sense_key=make%2:41:03:: | definition=charge with a function; charge to be | synonyms=name, nominate | examples=She was named Head of the Committee; She was made president of the club
21. sense_key=make%2:40:02:: | definition=achieve a point or goal | synonyms=have, get | examples=Nicklaus had a 70; The Brazilian team got 4 goals
22. sense_key=make%2:38:00:: | definition=reach a destination, either real or abstract | synonyms=reach, attain, hit, arrive at, gain | examples=We hit Detroit by noon; The water reached the doorstep
23. sense_key=make%2:31:13:: | definition=institute, enact, or establish | synonyms=lay down, establish | examples=make laws
24. sense_key=make%2:41:13:: | definition=carry out or commit | examples=make a mistake; commit a faux-pas
25. sense_key=make%2:41:01:: | definition=form by assembling individuals or constituents | examples=Make a quorum
26. sense_key=make%2:36:04:: | definition=organize or be responsible for | synonyms=hold, throw, have, give | examples=hold a reception; have, throw, or make a party
27. sense_key=make%2:30:02:: | definition=put in order or neaten | synonyms=make up | examples=make the bed; make up a room
28. sense_key=make%2:38:05:: | definition=head into a specified direction | synonyms=take | examples=The escaped convict took to the hills; We made for the mountains
29. sense_key=make%2:29:00:: | definition=have a bowel movement | synonyms=stool, defecate, shit, take a shit, take a crap, ca-ca | examples=The dog had made in the flower beds
30. sense_key=make%2:42:09:: | definition=undergo fabrication or creation | examples=This wool makes into a nice sweater
31. sense_key=make%2:42:13:: | definition=be suitable for | examples=Wood makes good furniture
32. sense_key=make%2:42:12:: | definition=add up to | examples=four and four make eight
33. sense_key=make%2:42:11:: | definition=amount to | examples=This salary increase makes no difference to my standard of living
34. sense_key=make%2:42:15:: | definition=constitute the essence of | examples=Clothes make the man
35. sense_key=make%2:39:12:: | definition=appear to begin an activity | examples=He made to speak but said nothing in the end; She made as if to say hello to us
36. sense_key=make%2:38:10:: | definition=proceed along a path | synonyms=work | examples=work one's way through the crowd; make one's way into the forest
37. sense_key=make%2:38:15:: | definition=reach in time | examples=We barely made the plane
38. sense_key=make%2:36:10:: | definition=gather and light the materials for | examples=make a fire
39. sense_key=make%2:36:07:: | definition=prepare for eating by applying heat | synonyms=cook, fix, ready, prepare | examples=Cook me dinner, please; can you make me an omelette?
40. sense_key=make%2:35:13:: | definition=induce to have sex | synonyms=seduce, score | examples=Harry finally seduced Sally; Did you score last night?
41. sense_key=make%2:32:14:: | definition=assure the success of | examples=A good review by this critic will make your play!
42. sense_key=make%2:32:09:: | definition=represent fictitiously, as in a play, or pretend to be or act like | synonyms=pretend, make believe | examples=She makes like an actress
43. sense_key=make%2:31:10:: | definition=consider as being | examples=It wasn't the problem some people made it
44. sense_key=make%2:31:12:: | definition=calculate as being | examples=I make the height about 100 feet
45. sense_key=make%2:30:10:: | definition=cause to be enjoyable or pleasurable | examples=make my day
46. sense_key=make%2:30:14:: | definition=favor the development of | examples=Practice makes the winner
47. sense_key=make%2:30:12:: | definition=develop into | examples=He will make a splendid father!
48. sense_key=make%2:29:06:: | definition=behave in a certain way | examples=make merry
49. sense_key=make%2:29:01:: | definition=eliminate urine | synonyms=urinate, piddle, puddle, micturate, piss, pee | examples=Again, the cat had made on the expensive rug

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "made" (past tense of "make") based on the provided context.

Context: "It made our New Year, "says Mr. Quinlan. This test was the first to predict reliably whether an individual could expect to develop cancer."

The phrase is "It made our New Year". This is an idiomatic expression.

Let's analyze the meaning of "made" in this specific context.
"It" refers to "This test" (the genetic test).
"our New Year" refers to the start of the year, or perhaps the period around it.

The phrase "It made our New Year" suggests that the test was a significant, positive, or memorable event during the New Year period.

I need to look through the candidate senses for a meaning that aligns with causing an event, creating a feeling, or making something special/memorable.

Candidate senses review:
1. make%2:41:00:: engage in (e.g., make love) - Unlikely.
2. make%2:30:00:: give certain properties to something (e.g., get someone mad) - Possible, but vague.
3. make%2:36:00:: make or cause to be or to become (synonyms=create) - General causation.
4. make%2:32:00:: cause to do; cause to act in a specified manner (synonyms=induce, stimulate, cause) - Possible.
5. make%2:36:08:: give rise to; cause to happen or occur, not always intentionally (synonyms=cause, do) - Strong candidate for causation.
6. make%2:36:01:: create or manufacture a man-made product - Physical creation. Unlikely.
7. make%2:31:00:: make, formulate, or derive in the mind (synonyms=draw) - Mental process. Unlikely.
8. make%2:36:15:: compel or make somebody or something to act in a certain way - Coercion. Unlikely.
9. make%2:36:09:: create by artistic means - Artistic creation. Unlikely.
10. make%2:40:01:: earn on some commercial or business transaction - Financial gain. Unlikely.
11. make%2:36:05:: create or design, often in a certain way - Design/shaping. Unlikely.
12. make%2:42:05:: to compose or represent - Composition. Unlikely.
13. make%2:38:02:: reach a goal - Attainment. Unlikely.
14. make%2:42:00:: be or be capable of being changed or made into - Potentiality. Unlikely.
15. make%2:36:11:: make by shaping or bringing together constituents - Physical assembly. Unlikely.
16. make%2:36:12:: perform or carry out - Execution. Unlikely.
17. make%2:36:13:: make by combining materials and parts - Construction. Unlikely.
18. make%2:30:15:: change from one form into another - Transformation. Unlikely.
19. make%2:29:08:: act in a certain way so as to acquire (e.g., make friends) - Acquiring/becoming. Possible, if "making New Year" means making a good start.
20. make%2:41:03:: charge with a function - Nomination. Unlikely.
21. make%2:40:02:: achieve a point or goal - Scoring. Unlikely.
22. make%2:38:00:: reach a destination - Arrival. Unlikely.
23. make%2:31:13:: institute, enact, or establish - Legislation. Unlikely.
24. make%2:41:13:: carry out or commit - Execution of action. Unlikely.
25. make%2:41:01:: form by assembling individuals or constituents - Assembly. Unlikely.
26. make%2:36:04:: organize or be responsible for - Organizing. Unlikely.
27. make%2:30:02:: put in order or neaten - Tidying. Unlikely.
28. make%2:38:05:: head into a specified direction - Movement. Unlikely.
29. make%2:29:00:: have a bowel movement - Biological function. Unlikely.
30. make%2:42:09:: undergo fabrication or creation - Becoming something. Unlikely.
31. make%2:42:13:: be suitable for - Suitability. Unlikely.
32. make%2:42:12:: add up to - Summation. Unlikely.
33. make%2:42:11:: amount to - Equivalence. Unlikely.
34. make%2:42:15:: constitute the essence of - Defining nature. Unlikely.
35. make%2:39:12:: appear to begin an activity - Pretending/feigning. Unlikely.
36. make%2:38:10:: proceed along a path - Movement. Unlikely.
37. make%2:38:15:: reach in time - Timeliness. Unlikely.
38. make%2:36:10:: gather and light the materials for - Fire starting. Unlikely.
39. make%2:36:07:: prepare for eating by applying heat - Cooking. Unlikely.
40. make%2:35:13:: induce to have sex - Sexual activity. Unlikely.
41. make%2:32:14:: assure the success of - Guaranteeing. Possible, if "making New Year" means ensuring a good start.
42. make%2:32:09:: represent fictitiously, as in a play, or pretend to be or act like - Pretending. Unlikely.
43. make%2:31:10:: consider as being - Assuming. Unlikely.
44. make%2:31:12:: calculate as being - Estimating. Unlikely.
45. make%2:30:10:: cause to be enjoyable or pleasurable (e.g., make my day) - This fits the idiomatic sense of making an event special or memorable.
46. make%2:30:14:: favor the development of - Promoting. Unlikely.
47. make%2:30:12:: develop into - Transformation. Unlikely.
48. make%2:29:06:: behave in a certain way - Conduct. Unlikely.
49. make%2:29:01:: eliminate urine - Biological function. Unlikely.

The phrase "It made our New Year" is a colloquial way of saying "It made our New Year special/memorable/a great start."

Sense 45: "cause to be enjoyable or pleasurable (examples=make my day)" is the closest match for this idiomatic usage, where the event (the test result) provided a positive, enjoyable, or significant experience during that time.

Let's confirm the relationship between "make my day" and "made our New Year." Both imply that the event caused a positive emotional impact or significance.

Therefore, sense 45 is the best fit.