[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (marked with `<t></t>`) is used in the provided context. The answer should be only the number.

2.  **Analyze the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer..."

3.  **Analyze the Senses:**
    *   Sense 1: definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
    *   Sense 2: definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

4.  **Apply Senses to the Context:**
    *   The context discusses people who *require treatment* (cancer patients).
    *   The phrase is "in patients who have not received chemotherapy."
    *   The word "patients" here refers to the recipients of the treatment/condition.

    *   *Check Sense 1:* "a person who requires medical care." This fits the context of cancer treatment.
    *   *Check Sense 2:* "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening." This also fits, as the patients are the affected group receiving the action (treatment).

5.  **Determine the Best Fit (Standard Interpretation):** In medical contexts, "patient" overwhelmingly refers to the person receiving care or treatment. Sense 1 captures this core meaning ("a person who requires medical care").

6.  **Final Selection:** Sense 1 is the most direct and primary meaning used in this medical context.


attempt_kind: initial

status: success

[User]
Which numbered sense of "medicine" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

finish_reason: stop

role: assistant

reasoning_content:
1.  **Analyze the Request:** The user wants me to identify which numbered sense of the word "medicine" (marked with `<t>medicines</t>`) is used in the provided context. I must return only the number.

2.  **Analyze the Context:**
    "What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable... in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer..."

3.  **Analyze the Target Word/Phrase:** The context uses "medicines for cancer."

4.  **Analyze the Senses:**
    *   Sense 1: definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
    *   Sense 2: definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
    *   Sense 3: definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
    *   Sense 4: definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

5.  **Match Context to Senses:**
    *   The context discusses Alimta and cisplatin, which are treatments/drugs used to treat cancer.
    *   Sense 1 (Branches of medical science/specialty) - Not the primary focus.
    *   Sense 2 (Something that treats or prevents or alleviates the symptoms of disease / medication/drug) - This aligns perfectly with using drugs (Alimta, cisplatin, chemotherapy) to treat cancer.
    *   Sense 3 (The learned profession/practice of medicine) - Not the focus; the text is about the drugs, not the profession itself.
    *   Sense 4 (Punishment/medicine) - Irrelevant.

6.  **Conclusion:** Sense 2 is the correct usage.

currency: USD

source: unavailable


[User]
Which numbered sense of "cancer" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. definition=type genus of the family Cancridae | synonyms=genus Cancer

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "cancer" (marked with `<t></t>`) is used in the provided context.

2.  **Analyze the Context:**
    "What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

3.  **Determine the Meaning of "cancer" in Context:**
    The context discusses:
    *   Treating diseases (pleural mesothelioma, non-small cell lung cancer).
    *   Malignant growth.
    *   Cancer being "unresectable" and "malignant" (having spread).
    *   Chemotherapy (medicines for cancer).
    *   The definition provided in the senses section (Sense 1) is: "any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream."

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
        *   *Match?* Yes. The context is entirely about medical cancer (malignant growth, spread, treatment).

    *   **Sense 2:** definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
        *   *Match?* No. (Astrology/Zodiac sign).

    *   **Sense 3:** definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
        *   *Match?* No. (Astronomy/Constellation).

    *   **Sense 4:** definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
        *   *Match?* No. (Astrology/Zodiac sign).

    *   **Sense 5:** definition=type genus of the family Cancridae | synonyms=genus Cancer
        *   *Match?* No. (Biology/Taxonomy).

5.  **Conclusion:** Sense 1 is the correct meaning used in the medical context.

6.  **Final Output Generation:** Return only the number. (1)


[User]
Which numbered sense of "advanced" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average
2. definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
3. definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
4. definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
5. definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
6. definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
7. definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
8. definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "advanced" (marked with `<t>advanced</t>`) is used in the provided context.

2.  **Examine the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy... before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells."

3.  **Determine the Meaning of "advanced" in Context:** The context is discussing cancer. The phrase is "advanced or metastatic non-small cell lung cancer." This refers to the stage or progression of the disease.

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average (Relates to development/stage.)
    *   **Sense 2:** definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion (Relates to stage/progression of illness.)
    *   **Sense 3:** definition=ahead of the times | synonyms=forward-looking, innovative, modern (Relates to time/technology.)
    *   **Sense 4:** definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics (Relates to education/skill level.)
    *   **Sense 5:** definition=ahead in development; complex or intricate | synonyms=sophisticated (Relates to complexity/technology.)
    *   **Sense 6:** definition=far along in time | synonyms=ripe (Relates to time/age.)
    *   **Sense 7:** definition=(of societies) highly developed especially in technology or industry (Relates to societal development.)
    *   **Sense 8:** definition=situated ahead or going before (Relates to position/time.)

5.  **Match Context to Senses:**
    The context uses "advanced" to describe the stage of cancer (metastatic, unresectable, spread).

    *   Sense 2: definition=comparatively late in a course of development; examples=the illness had reached an advanced stage. (This perfectly matches the medical context of disease progression.)

6.  **Conclusion:** Sense 2 is the correct meaning.


[User]
Which numbered sense of "cell" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=any small compartment | examples=the cells of a honeycomb
2. definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. definition=small room in which a monk or nun lives | synonyms=cubicle
7. definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "cell" is used in the provided context.

2.  **Analyze the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy... before advanced or metastatic non-small lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."
    The relevant phrase is: "non-small lung cancer that is not affecting the squamous cells."

3.  **Analyze the Target Word:** The word is "cell" (marked with <t>cell</t>).

4.  **Analyze the Senses:**

    *   Sense 1: definition=any small compartment | examples=the cells of a honeycomb (Relates to biological/structural units.)
    *   Sense 2: definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals (Defines the biological unit.)
    *   Sense 3: definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell (Relates to batteries/electronics.)
    *   Sense 4: definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre (Relates to politics/organizations.)
    *   Sense 5: definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone (Relates to telecommunications.)
    *   Sense 6: definition=small room in which a monk or nun lives | synonyms=cubicle (Relates to housing/rooms.)
    *   Sense 7: definition=a room where a prisoner is kept | synonyms=jail cell, prison cell (Relates to confinement/rooms.)

5.  **Match Context to Senses:**
    The context is entirely about cancer, medicine, and biological tissue ("lung cancer," "squamous cells"). This points strongly toward the biological definition of "cell."

    *   Sense 1 (small compartment/honeycomb) - Possible, but too general.
    *   Sense 2 (biology) - Highly relevant.
    *   Sense 3 (electric device) - Irrelevant.
    *   Sense 4 (political unit) - Irrelevant.
    *   Sense 5 (phone) - Irrelevant.
    *   Sense 6 (monk's room) - Irrelevant.
    *   Sense 7 (prison room) - Irrelevant.

6.  **Conclusion:** The context uses the biological definition of "cell." This corresponds to Sense 2.

7.  **Final Check:** The context discusses cancer cells. Sense 2 defines a cell as "the basic structural and functional unit of all organisms." This is the correct usage.


[User]
Which numbered sense of "affect" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Senses:
1. definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "affect" (marked with `<t>affecting</t>`) is used in the provided context.

2.  **Locate the Target Word and Context:**
    The word is `<t>affecting</t>`.
    The relevant sentence is: "...advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells."

3.  **Analyze the Contextual Usage:**
    The phrase is "not affecting the squamous cells."
    In this medical context, "affecting" means "impacting," "influencing," or "having an effect upon" the cells.

4.  **Examine the Senses:**

    *   **Sense 1:** definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
        *   *Match Check:* This definition aligns perfectly with the meaning used in the context ("not having an effect upon the cells").

    *   **Sense 2:** definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
        *   *Match Check:* This is also a strong candidate, as it means "have an effect upon."

    *   **Sense 3:** definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
        *   *Match Check:* This is about connection/involvement, not physical or cognitive impact. (Does not fit).

    *   **Sense 4:** definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
        *   *Match Check:* This is about deception. (Does not fit).

    *   **Sense 5:** definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd
        *   *Match Check:* This is about emotional/cognitive impact. While cancer treatment has emotional impact, the usage here ("affecting the squamous cells") is biological/physical, not emotional/cognitive. (Does not fit).

5.  **Compare Sense 1 and Sense 2:**
    *   Context: "...cancer that is not affecting the squamous cells."
    *   Sense 1: definition=have an effect upon.
    *   Sense 2: definition=act physically on; have an effect upon.

    Both Sense 1 and Sense 2 are highly relevant. However, Sense 1 is the most general and direct definition of "have an effect upon," which is exactly what is being described in the biological context (the cancer's influence on the cells). Sense 2 emphasizes the *physical action*, which is also true, but Sense 1 captures the overall meaning of influence/impact.

    Let's re-read the examples provided for Sense 1: "Will the new rules affect me?" (General impact).
    Let's re-read the examples provided for Sense 2: "the medicine affects my heart rate" (Physical action/effect).

    The context is biological (cancer affecting cells). Both 1 and 2 work. Since the context is about a biological process (cancer influencing cells), Sense 2 ("act physically on; have an effect upon") is arguably the most precise fit for the biological mechanism described.

    *Self-Correction/Refinement:* In standard usage, "affect" often covers both physical and non-physical influence. However, given the specific biological context ("squamous cells"), the physical action (Sense 2) is highly relevant.

    Let's stick with the definitions provided.
    Context: Cancer is not *doing something* to the cells.
    Sense 2: act physically on; have an effect upon. (Best fit for biological interaction).

6.  **Final Selection:** Sense 2.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "use" (marked with <t>used</t>) is employed in the provided context.

2.  **Analyze the Context:**
    "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy... Alimta is used in combination with cisplatin... and on its own in patients who have received another type of chemotherapy in the past."

3.  **Examine the Target Word:** The word is "used".

4.  **Analyze the Senses:**

    *   **Sense 1:** definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
        *   *Relevance:* This sense means employing something for a specific function or purpose. (e.g., "Alimta is used to treat cancer.")

    *   **Sense 2:** definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
        *   *Relevance:* This relates to consumption or habit. (e.g., "She uses drugs.")

    *   **Sense 3:** definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
        *   *Relevance:* This relates to depletion or consumption. (e.g., "The legislature expended its time.")

    *   **Sense 4:** definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
        *   *Relevance:* This relates to leveraging something for an advantage. (e.g., "She uses her friends to get jobs.")

    *   **Sense 5:** definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
        *   *Relevance:* This relates to making use of an opportunity or method.

    *   **Sense 6:** definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
        *   *Relevance:* This is the past habitual form ("used to").

5.  **Match Context to Senses:**
    The context repeatedly states what Alimta *does* or *is for* (its function/purpose).
    *   "Alimta is used to treat two types of cancer." (Employing it for a purpose.)
    *   "Alimta is used together with cisplatin..." (Employing it in combination.)
    *   "Alimta is used in combination with cisplatin..." (Employing it.)

    This aligns perfectly with Sense 1: "put into service; make work or employ for a particular purpose."

6.  **Conclusion:** The correct sense is 1.


[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (marked with `<t></t>`) is used in the provided context. The answer should be only the number.

2.  **Examine the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy... Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

3.  **Analyze the Target Word/Phrase:** The target is "patients".

4.  **Examine the Senses:**
    *   Sense 1: definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
    *   Sense 2: definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

5.  **Apply Senses to the Context:**
    *   The context discusses cancer treatment (Alimta, cisplatin, chemotherapy).
    *   The phrase is "in patients who have not received chemotherapy" and "in patients who have received another type of chemotherapy."
    *   In this context, "patients" refers to individuals who are receiving or are affected by the treatment/disease.

    *   *Check Sense 1:* "a person who requires medical care." (This is true, as they are receiving cancer treatment.)
    *   *Check Sense 2:* "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening." (This is also true; they are the recipients/affected parties of the treatment.)

6.  **Determine the Best Fit (Semantic Role vs. Definition):**
    *   The context uses "patients" as the recipients of the medical intervention.
    *   Sense 1 provides a definition ("a person who requires medical care").
    *   Sense 2 provides a grammatical/semantic function ("the semantic role... affected by the happening").

    *   While Sense 1 is a valid definition, Sense 2 specifically captures the role of the entity within the sentence structure (the entity being affected by the action/treatment). Since the context is highly focused on the *role* of these individuals in the treatment scheme, Sense 2 is a very strong fit, especially given the synonym "patient role."

7.  **Final Selection:** Sense 2 describes the entity's function in the sentence (being affected by the treatment), which is precisely what the text is describing.


[User]
Which numbered sense of "treat" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. definition=regard or consider in a specific way | examples=I treated his advances as a joke

reasoning_content:
1.  **Analyze the Request:** The goal is to identify the correct numbered sense of the word "treat" (<t>treated</t>) in the provided context.

2.  **Examine the Context:**
    "Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past."

3.  **Analyze the Target Word Usage:** The phrase is "have not been treated before." This refers to a medical intervention (chemotherapy/medicine) being administered to a patient.

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please (Focuses on interaction/handling/dealing with someone/something.)
    *   **Sense 2:** definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair (Focuses on undergoing a process/treatment.)
    *   **Sense 3:** definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims (Focuses on giving medical care/treatment.)
    *   **Sense 4:** definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address (Focuses on dealing with a topic/subject.)
    *   **Sense 5:** definition=provide with a gift or entertainment (Focuses on giving a gift/entertainment.)
    *   **Sense 6:** definition=provide with choice or abundant food or drink (Focuses on providing food/drink/regaling.)
    *   **Sense 7:** definition=engage in negotiations in order to reach an agreement (Focuses on negotiation.)
    *   **Sense 8:** definition=regard or consider in a specific way (Focuses on considering something.)

5.  **Match Context to Senses:**
    The context is about medical intervention (chemotherapy).

    *   Sense 3: definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg... (This strongly matches the medical context.)
    *   Sense 2: definition=subject to a process or treatment... (This is grammatically possible, but the structure "have not been treated" usually implies the patient is the recipient of the action, aligning better with Sense 3 or a passive form of Sense 2.)

6.  **Conclusion:** The context clearly relates to receiving medical care/treatment. Sense 3 is the most appropriate fit.


[User]
Which numbered sense of "patient" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "patient" (<t>patients</t>) is used in the provided context. The answer should be only the number.

2.  **Analyze the Context:**
    "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past."

3.  **Analyze the Senses:**
    *   Sense 1: definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
    *   Sense 2: definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

4.  **Apply Senses to the Target Word (<t>patients</t>):**

    *   *Context usage:* "...in patients who have not been treated before..." and "...in patients who have received another type of chemotherapy..."
    *   *Interpretation:* These patients are the recipients of the treatment (chemotherapy). They are the entities being affected by the medical intervention.

    *   *Check Sense 1:* "a person who requires medical care." (This is true, but the context focuses on their status regarding *prior treatment*.)
    *   *Check Sense 2:* "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening..." (This fits perfectly. The patients are the entities affected by the chemotherapy.)

5.  **Conclusion:** The usage in the context aligns with the semantic role sense (Sense 2).

6.  **Final Answer Formulation:** The correct sense number is 2.


[User]
Which numbered sense of "type" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Senses:
1. definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. definition=printed characters | examples=small type is hard to read
5. definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "type" (<t>type</t>) is used in the provided context.

2.  **Analyze the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription."

3.  **Identify the Target Word/Phrase:** The target is `<t>type</t>`. I need to look at the specific instances where "type" is used and determine its meaning.

    *   Instance 1: "treat two types of cancer" (Meaning: categories/kinds).
    *   Instance 2: "another type of chemotherapy" (Meaning: a category/kind of chemotherapy).

4.  **Analyze the Senses:**

    *   Sense 1: definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer? (Focuses on categories/subdivisions.)
    *   Sense 2: definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case (Focuses on a person/character.)
    *   Sense 3: definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon (Focuses on biological classification/grouping.)
    *   Sense 4: definition=printed characters | examples=small type is hard to read (Focuses on typography/font.)
    *   Sense 5: definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character (Focuses on character sets/tokens.)
    *   Sense 6: definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper (Focuses on a physical type/character.)

5.  **Match Context Usage to Senses:**

    *   The context uses "types of cancer" and "type of chemotherapy." Both usages refer to categories or kinds of things.
    *   Sense 1: "a subdivision of a particular kind of thing." This fits perfectly ("two types of cancer," "type of chemotherapy").
    *   Sense 2: Does not fit (no mention of people/characters).
    *   Sense 3: Does not fit (not biological taxonomy).
    *   Sense 4/6: Do not fit (not about printed characters or metal blocks).
    *   Sense 5: Does not fit (not about tokens of a symbol).

6.  **Conclusion:** The context uses "type" in the sense of a subdivision or category. This corresponds to Sense 1.

7.  **Final Check:** The question asks for the number of the correct sense. The correct sense is 1.


[User]
Which numbered sense of "past" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Senses:
1. definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. definition=a verb tense that expresses actions or states in the past | synonyms=past tense

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of "past" (marked with <t>past</t>) is used in the provided context.

2.  **Examine the Context:**
    "Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer... Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>."

3.  **Analyze the Target Word/Phrase:** The word is "past" within the structure "...patients who have received another type of chemotherapy in the past."

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
        *   *Check against context:* "in the past" refers to a time period that has elapsed (a previous time). This matches Sense 1.

    *   **Sense 2:** definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
        *   *Check against context:* The context is about medical treatment history, not a secret period of life. This does not match Sense 2.

    *   **Sense 3:** definition=a verb tense that expresses actions or states in the past | synonyms=past tense
        *   *Check against context:* The word "past" here is used as a noun describing a time period, not as a grammatical tense (e.g., "I walked yesterday" uses the past tense). This does not match Sense 3.

5.  **Conclusion:** The usage "in the past" refers to a previous time period or elapsed time, which corresponds to Sense 1.

6.  **Final Answer Formulation:** Return only the number.


[User]
Which numbered sense of "medicine" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Senses:
1. definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "medicine" (marked with `<t>medicine</t>`) is used in the provided context.

2.  **Examine the Context:**
    "It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin (another anticancer medicine)... Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy (medicines for cancer)... The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?"

3.  **Analyze the Target Word Usage:** The context uses "medicine" in the sentence: "The medicine can only be obtained with a prescription." This usage refers to a substance or treatment prescribed by a doctor.

4.  **Evaluate the Senses:**

    *   **Sense 1:** definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty. (Focuses on the *science/field*.) -> *Does not fit.*
    *   **Sense 2:** definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug. (Focuses on the *substance/treatment*.) -> *Fits well.*
    *   **Sense 3:** definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard. (Focuses on the *profession/practice*.) -> *Does not fit the specific usage "the medicine" (referring to the drug/treatment).*
    *   **Sense 4:** definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine. (Focuses on *punishment* or the idiom "take your medicine".) -> *Does not fit the context of obtaining a prescription drug.*

5.  **Conclusion:** The context uses "medicine" to refer to the substance or treatment (Alimta/the drug) that is prescribed. This aligns with Sense 2.

6.  **Final Check:** Sense 2: "(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug." This matches the context where Alimta is discussed as a treatment.


[User]
Which numbered sense of "only" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Senses:
1. definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. definition=in the final outcome | examples=These news will only make you more upset
5. definition=except that | examples=It was the same story; only this time she came out better
6. definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. definition=as recently as | examples=I spoke to him only an hour ago

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of "only" (marked with <t>only</t>) is used in the provided context and return only the number.

2.  **Locate the Target Word and Context:**
    The sentence containing the target word is: "The medicine can <t>only</t> be obtained with a prescription."

3.  **Analyze the Usage of "only" in Context:**
    "The medicine can only be obtained with a prescription."
    This means that obtaining the medicine is restricted *only* to the condition of having a prescription. It implies exclusivity or necessity.

4.  **Evaluate the Provided Senses:**

    *   **Sense 1:** definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time (Focuses on limitation/restriction, often meaning 'just' or 'nothing more').
    *   **Sense 2:** definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children (Focuses on exclusivity/sole source).
    *   **Sense 3:** definition=with nevertheless the final result (Focuses on consequence/result).
    *   **Sense 4:** definition=in the final outcome (Focuses on result/consequence).
    *   **Sense 5:** definition=except that (Focuses on exception).
    *   **Sense 6:** definition=never except when | synonyms=only if, only when (Focuses on conditionality).
    *   **Sense 7:** definition=as recently as (Focuses on time).

5.  **Match Context to Senses:**
    The phrase "only be obtained with a prescription" means that a prescription is the *sole* or *exclusive* requirement.

    *   Sense 2: definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone. This matches the meaning of exclusivity ("only" means "exclusively").

6.  **Conclusion:** Sense 2 is the correct usage.


[User]
Which numbered sense of "obtain" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Senses:
1. definition=come into possession of | examples=How did you obtain the visa?
2. definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "obtain" (marked with `<t>obtained</t>`) is used in the provided context.

2.  **Examine the Context:** "The medicine can only be <t>obtained</t> with a prescription."

3.  **Analyze the Target Word in Context:** "obtained" means that the medicine can only be acquired or procured through a specific method (a prescription).

4.  **Analyze the Senses Provided:**
    *   Sense 1: definition=come into possession of | examples=How did you obtain the visa? (Focuses on acquiring/getting something.)
    *   Sense 2: definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review (Focuses on receiving/incurring something, often abstractly or as a treatment.)
    *   Sense 3: definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds (Focuses on validity.)

5.  **Match Context to Senses:**
    *   Context: "The medicine can only be obtained with a prescription." (Meaning: The medicine can only be acquired/gotten with a prescription.)
    *   Sense 1: "come into possession of" (Acquiring/getting something.) -> This matches the context perfectly.
    *   Sense 2: "receive a specified treatment" (Receiving a treatment.) -> Does not fit the context of acquiring the medicine itself.
    *   Sense 3: "be valid, applicable, or true" (Validity.) -> Does not fit the context.

6.  **Conclusion:** The correct sense is Sense 1.


[User]
Which numbered sense of "prescription" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Senses:
1. definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. definition=written instructions for an optician on the lenses for a given person
4. definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

reasoning_content:
1.  **Analyze the Request:** The user wants to identify which numbered sense of the word "prescription" (marked with `<t>prescription</t>`) is used in the provided context.

2.  **Analyze the Context:**
    "It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma... Alimta is used together with cisplatin... in patients who have not received chemotherapy... Alimta is used in combination with cisplatin... The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?"

3.  **Determine the Meaning of "prescription" in Context:** The sentence "The medicine can only be obtained with a prescription" refers to the official authorization or written order required by a doctor for obtaining the drug.

4.  **Analyze the Senses:**

    *   **Sense 1:** definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success (Focuses on directions/rules.)
    *   **Sense 2:** definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly (Focuses on the drug itself, obtained via written instructions.)
    *   **Sense 3:** definition=written instructions for an optician on the lenses for a given person (Specific to eyewear.)
    *   **Sense 4:** definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient (Focuses on instructions for dispensing a drug.)

5.  **Match Context to Senses:**
    The context states that the *medicine* (Alimta) can only be obtained with a prescription. This points toward the concept of the written authorization/order for a drug.

    *   Sense 1 (Directions/Rules) - Plausible, but less specific to the drug context.
    *   Sense 2 (A drug available only with written instructions) - Very strong match.
    *   Sense 3 (Optician lenses) - Incorrect.
    *   Sense 4 (Written instructions from physician/dentist to druggist concerning form and dosage) - Very strong match, focusing on the process of obtaining the drug.

6.  **Refine the Choice between Sense 2 and Sense 4:**
    The context is: "The medicine can only be obtained with a prescription."
    Sense 2 defines "prescription" as "a drug that is available only with written instructions from a doctor or dentist to a pharmacist."
    Sense 4 defines "prescription" as "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient."

    Both 2 and 4 are highly relevant. However, Sense 4 describes the *document* (the written instructions) that authorizes the drug's dispensing, which is exactly what is required to "obtain" the medicine. Sense 2 defines the *drug itself* as being available only with these instructions. Since the context is about obtaining the medicine, Sense 4 is the most precise fit for the function of the word in this specific sentence structure.

    *Self-Correction/Re-evaluation:* Let's look at the examples.
    Sense 2 example: "he had been taking his prescription regularly" (Focuses on taking the drug.)
    Sense 4 definition: "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient" (Focuses on the instructions/order.)

    The context is about *obtaining* the medicine. Sense 4 describes the written instructions used for that purpose.

7.  **Final Selection:** Sense 4.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Senses:
1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

reasoning_content:
1.  **Analyze the Request:** The goal is to identify the correct numbered sense of the word "use" (marked with <t>used</t>) in the provided context and return only the number.

2.  **Analyze the Context:**
    "How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

3.  **Analyze the Target Word in Context:** The word is "used" in the phrase "How is Alimta used?" and "qualified in the use of anticancer chemotherapy."

4.  **Analyze the Senses:**

    *   **Sense 1:** definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
        *   *Relevance:* This sense means employing something for a specific purpose. This fits the context of how a medicine (Alimta) is employed or applied.

    *   **Sense 2:** definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
        *   *Relevance:* This relates to consumption/habitual action, not the manner in which a drug is applied or employed. (Less relevant)

    *   **Sense 3:** definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
        *   *Relevance:* This relates to depletion or consumption, not the application/employment of the medicine. (Not relevant)

    *   **Sense 4:** definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
        *   *Relevance:* This relates to strategic advantage, not the medical application of a drug. (Not relevant)

    *   **Sense 5:** definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
        *   *Relevance:* This is similar to Sense 1 (apply/practice), but Sense 1 is a stronger fit for "put into service" or "employ for a purpose."

    *   **Sense 6:** definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
        *   *Relevance:* This is about past habit, not the current instruction/application of the drug. (Not relevant)

5.  **Conclusion:** Sense 1 ("put into service; make work or employ for a particular purpose") is the most accurate fit for describing how a medical treatment is employed or applied.


[User]
Which numbered sense of "only" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Senses:
1. definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. definition=in the final outcome | examples=These news will only make you more upset
5. definition=except that | examples=It was the same story; only this time she came out better
6. definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. definition=as recently as | examples=I spoke to him only an hour ago

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of "only" (marked with <t>only</t>) is used in the provided context.

2.  **Locate the Target Phrase:** The phrase is: "Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

3.  **Analyze the Contextual Meaning:** The sentence restricts the condition for giving Alimta. It means that the *only* requirement or condition is that it must be given under the supervision of a qualified doctor. It implies exclusivity or limitation.

4.  **Examine the Senses:**

    *   **Sense 1:** definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time (Focuses on limitation/restriction of scope.)
    *   **Sense 2:** definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children (Focuses on exclusivity/singularity.)
    *   **Sense 3:** definition=with nevertheless the final result (Focuses on contrast/concession.)
    *   **Sense 4:** definition=in the final outcome (Focuses on result/consequence.)
    *   **Sense 5:** definition=except that (Focuses on exception.)
    *   **Sense 6:** definition=never except when (Focuses on conditionality.)
    *   **Sense 7:** definition=as recently as (Focuses on time.)

5.  **Match Context to Senses:**

    *   The context states that the *only* condition is supervision by a qualified doctor. This strongly aligns with the idea of exclusivity or singularity (Sense 2: without any others being included or involved).

    *   *Self-Correction/Refinement:*
        *   If I say "You can only have cake," it means cake is the *only* thing allowed (Sense 2).
        *   If I say "I was only asking," it means I was *merely* asking (Sense 1).
        *   The structure "Alimta should only be given under X" means X is the sole prerequisite.

6.  **Conclusion:** Sense 2 (without any others being included or involved; exclusively, solely) is the best fit.


[User]
Which numbered sense of "give" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Senses:
1. definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. definition=convey or reveal information | examples=Give one's name
5. definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. definition=emit or utter | examples=Give a gulp; give a yelp
16. definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. definition=give (as medicine) | examples=I gave him the drug
20. definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. definition=bestow | synonyms=render | examples=give homage; render thanks
22. definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. definition=execute and deliver | examples=Give bond
29. definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. definition=present to view | examples=He gave the sign to start
32. definition=perform for an audience | examples=Pollini is giving another concert in New York
33. definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. definition=propose | examples=He gave the first of many toasts at the birthday party
35. definition=accord by verdict | examples=give a decision for the plaintiff
36. definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. definition=offer in good faith | examples=He gave her his word
38. definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. definition=allow to have or take | examples=I give you two minutes to respond
41. definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. definition=occur | examples=what gives?
43. definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. definition=proffer (a body part) | examples=She gave her hand to her little sister

reasoning_content:
The user wants me to identify the correct numbered sense of the verb "give" in the context: "Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

1.  **Analyze the context:** "Alimta should only be given under the supervision of a doctor..."
2.  **Analyze the word form:** The word is "given," which is the past participle of "give." In this sentence, it is part of a passive construction ("should only be given").
3.  **Determine the meaning of "given" in this context:** It means administered, provided, or supplied (in a medical context).

4.  **Review the senses of "give" and look for relevant definitions:**

    *   1. definition=cause to have, in the abstract sense or physical sense
    *   2. definition=be the cause or source of
    *   3. definition=transfer possession of something concrete or abstract to somebody (e.g., I gave her my money)
    *   4. definition=convey or reveal information
    *   5. definition=convey, as of a compliment, regards, attention, etc.; bestow
    *   6. definition=organize or be responsible for
    *   7. definition=convey or communicate; of a smile, a look, a physical gesture
    *   8. definition=give as a present; make a gift of
    *   9. definition=cause to happen or be responsible for
    *   10. definition=dedicate
    *   11. definition=give or supply (synonyms=render, yield, return, generate)
    *   12. definition=transmit (knowledge or skills)
    *   13. definition=bring about
    *   14. definition=leave with; give temporarily
    *   15. definition=emit or utter
    *   16. definition=endure the loss of
    *   17. definition=place into the hands or custody of (synonyms=pass, hand, reach, pass on, turn over)
    *   18. definition=give entirely to a specific person, activity, or cause
    *   19. definition=give (as medicine)
    *   20. definition=give or convey physically (synonyms=apply)
    *   21. definition=bestow (synonyms=render)
    *   22. definition=bestow, especially officially (synonyms=grant)
    *   23. definition=move in order to make room for someone for something
    *   24. definition=give food to (synonyms=feed)
    *   25. definition=contribute to some cause
    *   26. definition=break down, literally or metaphorically
    *   27. definition=estimate the duration or outcome of something
    *   28. definition=execute and deliver
    *   29. definition=deliver in exchange or recompense
    *   30. definition=afford access to
    *   31. definition=present to view
    *   32. definition=perform for an audience
    *   33. definition=be flexible under stress of physical force
    *   34. definition=propose
    *   35. definition=accord by verdict
    *   36. definition=manifest or show
    *   37. definition=offer in good faith
    *   38. definition=submit for consideration, judgment, or use
    *   39. definition=guide or direct, as by behavior of persuasion
    *   40. definition=allow to have or take
    *   41. definition=inflict as a punishment
    *   42. definition=occur
    *   43. definition=consent to engage in sexual intercourse with a man
    *   44. definition=proffer (a body part)

5.  **Match the context ("given" as medicine/treatment) to the senses:**

    *   Sense 19: definition=give (as medicine) | examples=I gave him the drug
    *   Sense 20: definition=give or convey physically | examples=She gave him First Aid; I gave him a punch in the nose
    *   Sense 21: definition=bestow | synonyms=render | examples=give homage; render thanks
    *   Sense 22: definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce

    The context is about administering a medicine (Alimta). Sense 19 is the most direct fit.

    *   Context: Alimta should only be given...
    *   Sense 19: definition=give (as medicine)

6.  **Final check:** The usage is clearly medical/pharmacological. Sense 19 is defined specifically as "give (as medicine)".


[User]
Which numbered sense of "doctor" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Senses:
1. definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
2. definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
3. definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
4. definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

reasoning_content:
1.  **Analyze the Request:** The user wants to know which numbered sense of the word "doctor" (marked with `<t>doctor</t>`) is used in the provided context. The answer should be only the number.

2.  **Examine the Context:**
    "Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy."

3.  **Analyze the Senses:**
    *   Sense 1: definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
    *   Sense 2: definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
    *   Sense 3: definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
    *   Sense 4: definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

4.  **Match the Context to the Senses:**
    *   The context refers to a person supervising the use of anticancer chemotherapy. This is a medical professional.
    *   Sense 1: "a licensed medical practitioner." (Matches the context perfectly.)
    *   Sense 2: "a title conferred on 33 saints." (Irrelevant.)
    *   Sense 3: "children take the roles of physician..." (Irrelevant.)
    *   Sense 4: "a person who holds Ph.D. degree." (While a doctor often has a Ph.D., the primary meaning here is the *practice* of medicine/licensure, not just the academic degree.)

5.  **Conclusion:** The context uses the meaning of "doctor" as a licensed medical practitioner. This corresponds to Sense 1.

6.  **Final Output Generation:** Return only the number 1.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Senses:
1. definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
3. definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
5. definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
6. definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
7. definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

reasoning_content:
1.  **Analyze the Request:** The goal is to identify which numbered sense of the word "use" (marked with `<t>use</t>`) is used in the provided context.

2.  **Locate the Target Word and Context:**
    The sentence containing the target word is: "Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy."

3.  **Analyze the Contextual Meaning:**
    The phrase is "qualified in the *use* of anticancer chemotherapy." This implies competence, skill, or the ability to apply/employ a method or technique.

4.  **Examine the Senses:**

    *   **Sense 1:** definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
        *   *Match Check:* "skilled in the utilization" strongly aligns with the idea of competence/skill in applying something.

    *   **Sense 2:** definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
        *   *Match Check:* This relates to purpose/function. The context is about the doctor's skill, not the purpose of chemotherapy itself.

    *   **Sense 3:** definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
        *   *Match Check:* This is too abstract (a service).

    *   **Sense 4:** definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | examples=the consumption of energy has increased steadily
        *   *Match Check:* Irrelevant (economics).

    *   **Sense 5:** definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
        *   *Match Check:* Irrelevant (psychology/habit).

    *   **Sense 6:** definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
        *   *Match Check:* Irrelevant (influence/manipulation).

    *   **Sense 7:** definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat
        *   *Match Check:* Irrelevant (legal right/enjoyment).

5.  **Conclusion:** Sense 1 (the act of using/utilization/employment) is the correct fit, as the context refers to the skill required to apply chemotherapy.