[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduce
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
3. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
4. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
5. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
6. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down
7. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
8. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
9. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
10. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
11. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
12. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
13. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
14. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
15. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
16. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
17. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
18. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
19. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
20. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target word: "reduce"
    *   Context: "To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid..."
    *   Meaning: In this context, "reduce" means to make the side effects less severe, less frequent, or smaller in number/intensity.

    *   1: cut down on; make a reduction in (e.g., fat intake, health benefits) - *Possible, but usually refers to quantity of something consumed or provided.*
    *   2: cook until very little liquid is left - *Incorrect.*
    *   3: reduce in size; reduce physically (shrink) - *Incorrect.*
    *   4: make smaller (scale down) - *Incorrect.*
    *   5: narrow or limit (tighten) - *Incorrect.*
    *   6: take off weight - *Incorrect.*
    *   7: be cooked until very little liquid is left - *Incorrect.*
    *   8: destress a sound - *Incorrect.*
    *   9: reduce in scope while retaining essential elements (abridge) - *Incorrect.*
    *   10: lessen and make more modest (e.g., standard of living) - *Close, but usually refers to lifestyle/status.*
    *   11: be the essential element (boil down) - *Incorrect.*
    *   12: reposition a broken bone - *Incorrect.*
    *   13: simplify a mathematical equation - *Incorrect.*
    *   14: lower in grade or rank - *Incorrect.*
    *   15: undergo meiosis - *Incorrect.*
    *   16: remove oxygen (chemistry) - *Incorrect.*
    *   17: lessen strength/flavor of a solution (dilute) - *Incorrect.*
    *   18: bring to humbler or weaker state - *Incorrect.*
    *   19: put down by force - *Incorrect.*
    *   20: make less complex - *Incorrect.*

    *   Sense 1: "cut down on; make a reduction in" (Synonyms: cut down, cut back, trim).
    *   Sense 10: "lessen and make more modest" (Example: reduce one's standard of living).

    Wait, let me look at the senses again. Is there a better one?
    "To reduce side effects" means to decrease the intensity or frequency of the side effects.

    Let's re-examine Sense 1: "cut down on; make a reduction in".
    Example: "reduce your daily fat intake".
    This fits the idea of decreasing the amount or intensity of something.

    Let's re-examine Sense 10: "lessen and make more modest".
    Example: "reduce one's standard of living".
    This feels more about status or quality of life.

    Are there any other options?
    Sense 4: "make smaller" (scale down).
    Sense 5: "narrow or limit".

    Actually, looking at the provided senses, Sense 1 ("cut down on; make a reduction in") is the most general sense for decreasing the amount, intensity, or frequency of something (like side effects).

    Let's double-check if "reduce" in "reduce side effects" fits "cut down on".
    "Cut down on side effects" is a common way to say "reduce side effects".

    Wait, let me look at the list again. Is there a "lessen" sense?
    Sense 10: "lessen and make more modest".
    Sense 17: "lessen the strength or flavor of a solution".

    Let's compare Sense 1 and Sense 10 again.
    Sense 1: "cut down on; make a reduction in"
    Sense 10: "lessen and make more modest"

    "Reduce side effects" is about decreasing the occurrence or severity. "Cut down on" fits this well.

    Let's check if there's any other sense I missed.
    Sense 1: cut down on; make a reduction in.
    Sense 10: lessen and make more modest.

    In medical contexts, "reduce side effects" usually means to decrease their frequency or severity. Sense 1 is the most appropriate general sense for "decrease/lessen" among the choices provided.

    Wait, let me look at Sense 1 again. "cut down on; make a reduction in".
    Example: "reduce your daily fat intake".
    This is about quantity. Side effects can be quantified (number of side effects) or their intensity can be reduced.

    Is there any other sense?
    Sense 4: "make smaller" (scale down).
    Sense 5: "narrow or limit".

    Let's look at Sense 1 again. "cut down on; make a reduction in". This is the most standard sense for "reduce" when it means "decrease".

    Let's re-read Sense 10: "lessen and make more modest". This is very specific to things like "standard of living".

    Therefore, Sense 1 is the best fit.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: side_effect
Target surface form: side effects
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce <t>side effects</t>, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
2. sense_key=side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

finish_reason: stop

content:
```json
{"sense_index": 1}
```

role: assistant

reasoning_content:
*   Target lemma: `side_effect`
    *   Target surface form: `side effects`
    *   Context: A medical text describing the use of Alimta (anticancer chemotherapy), mentioning dosage, administration, and the use of corticosteroids, folic acid, and vitamin B12 to reduce "side effects".
    *   Candidate senses:
        1.  `side_effect%1:26:00::`: a secondary and usually adverse effect of a drug or therapy.
        2.  `side_effect%1:19:00::`: any adverse and unwanted secondary effect (synonym: fallout).

    *   The context is explicitly about a medicine (Alimta), chemotherapy, and medical treatment.
    *   The phrase "To reduce side effects, patients should take a corticosteroid..." clearly refers to the adverse effects caused by the drug/therapy.

    *   Sense 1 specifically mentions "drug or therapy".
    *   Sense 2 is a more general "adverse and unwanted secondary effect" (like political or social fallout).

    *   Sense 1 is the precise fit for a medical context involving chemotherapy.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, <t>patients</t> should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role
2. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text describing the use of Alimta (chemotherapy). It mentions prescriptions, doctors, doses based on height/weight, and that "patients should take a corticosteroid and folic acid".
    *   Candidate senses:
        1.  `patient%1:10:00::`: Semantic role of an entity affected by a verb (linguistics).
        2.  `patient%1:18:00::`: A person who requires medical care.

    *   The context is clearly medical ("medicine", "prescription", "anticancer chemotherapy", "doctor", "dose", "intravenous infusion").
    *   The sentence "To reduce side effects, <t>patients</t> should take a corticosteroid..." refers to the people receiving the medical treatment.

    *   Sense 1 is a linguistic term (semantic role).
    *   Sense 2 is a medical term (person receiving care).

    *   Sense 2 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
2. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
3. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up
6. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `type`
    *   Target surface form: `type`
    *   Context: "...patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin)..."
    *   Candidate senses:
        1.  `type%1:10:00::`: all of the tokens of the same symbol (e.g., characters in a word).
        2.  `type%1:14:01::`: (biology) taxonomic group.
        3.  `type%1:18:00::`: a person of a specified kind (eccentric).
        4.  `type%1:10:01::`: printed characters.
        5.  `type%1:06:00::`: small metal block for printing.
        6.  `type%1:09:00::`: a subdivision of a particular kind of thing.

    *   The phrase is "a type of vitamin".
    *   Folic acid is a specific kind or category within the broader group of vitamins.
    *   This matches the definition of "a subdivision of a particular kind of thing".

    *   Sense 1: Not about symbols/tokens.
    *   Sense 2: Not about taxonomic groups in the biological classification sense (Kingdom, Phylum, etc.), though vitamins are chemical compounds.
    *   Sense 3: Not about a person.
    *   Sense 4: Not about printed characters.
    *   Sense 5: Not about printing blocks.
    *   Sense 6: "a subdivision of a particular kind of thing" (Example: "what type of sculpture do you prefer?"). This fits perfectly.

    *   The best sense is sense 6.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: injection
Target surface form: injections
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=injection%1:27:00:: | definition=any solution that is injected (as into the skin) | synonyms=injectant
2. sense_key=injection%1:04:00:: | definition=the forceful insertion of a substance under pressure
3. sense_key=injection%1:04:01:: | definition=the act of putting a liquid into the body by means of a syringe | synonyms=shot | examples=the nurse gave him a flu shot

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `injection`
    *   Target surface form: `injections`
    *   Context: "...patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta."
    *   Candidate senses:
        1.  `injection%1:27:00::`: any solution that is injected (as into the skin) (synonym: injectant)
        2.  `injection%1:04:00::`: the forceful insertion of a substance under pressure
        3.  `injection%1:04:01::`: the act of putting a liquid into the body by means of a syringe (synonym: shot)

    *   The sentence says "receive injections of vitamin B12".
    *   In a medical context, "receiving an injection" usually refers to the procedure/act of being given the medicine via a syringe (Sense 3) or the substance itself (Sense 1).
    *   Let's compare Sense 1 and Sense 3.
        *   Sense 1: "any solution that is injected" (the substance).
        *   Sense 3: "the act of putting a liquid into the body by means of a syringe" (the procedure/shot).
    *   Common usage: "receive an injection" typically refers to the act/event of getting a shot. If it meant the substance, it would more likely be "receive vitamin B12 injections" (where injections modifies vitamin B12) or "receive the injection". However, "receive injections of vitamin B12" strongly suggests the administration process (the shots).
    *   Looking at the synonyms: Sense 3 has "shot". "Receive shots of vitamin B12" is a very natural paraphrase.
    *   Sense 1 is the "injectant" (the liquid itself). While technically the patient receives the liquid, the phrase "receive injections" almost always refers to the medical act/event.

    *   Sense 1: The liquid.
    *   Sense 2: Forceful insertion (too general/mechanical).
    *   Sense 3: The act of injecting/a shot.

    In "receive injections of vitamin B12", "injections" refers to the medical procedure of administering the drug.

    *   Sense 3: "the act of putting a liquid into the body by means of a syringe" / "shot".
    *   This fits perfectly.

    *   Wait, could it be Sense 1? "any solution that is injected".
    *   If I say "I need an injection of courage", that's metaphorical.
    *   If I say "The nurse prepared the injection", it could be the liquid (Sense 1) or the act (Sense 3).
    *   If I say "He received three injections", it usually means three shots (Sense 3).
    *   In the context of "receive injections of vitamin B12", it refers to the administration events.

    *   Sense 1: injectant (the substance).
    *   Sense 3: shot (the act).
    *   "Receive injections" -> "Receive shots". This is the standard interpretation.

    *   Sense 1: solution that is injected.
    *   Sense 3: act of putting a liquid into the body.
    *   In medical texts, "receive injections" refers to the administration.

    Let's double-check Sense 1 again. "any solution that is injected". If the text meant the solution, it would likely say "receive vitamin B12 solution" or "receive vitamin B12 via injection". "Receive injections of [substance]" is the standard way to describe the act of being shot.

    Therefore, Sense 3 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during <t>treatment</t> with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
2. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
3. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased
4. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "treatment"
    *   Target surface form: "treatment"
    *   Context: A medical text describing the use of Alimta (an anticancer chemotherapy drug), dosage, administration, and side effect management. The specific phrase is "receive injections of vitamin B12 during <t>treatment</t> with Alimta."

    *   Sense 1: `treatment%1:04:01::` - the management of someone or something (synonym: handling). Example: handling of prisoners.
    *   Sense 2: `treatment%1:04:00::` - care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) (synonym: intervention).
    *   Sense 3: `treatment%1:10:00::` - an extended communication dealing with some particular topic (synonyms: discussion, discourse).
    *   Sense 4: `treatment%1:07:00::` - a manner of dealing with something artistically.

    *   The context is clearly medical: "medicine", "prescription", "anticancer chemotherapy", "dose", "intravenous infusion", "side effects", "corticosteroid", "folic acid", "vitamin B12".
    *   The phrase "during treatment with Alimta" refers to the period during which the patient is receiving the medical care/drug to treat their condition.
    *   This aligns perfectly with Sense 2: "care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury)".

    *   Sense 1 (handling) is too general and doesn't fit the medical context.
    *   Sense 3 (discussion) is about communication/writing.
    *   Sense 4 (artistic) is about art.

    *   Sense 2 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is <t>given</t> with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
2. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
3. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
4. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
5. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
6. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
7. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
10. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
11. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
12. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
13. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
14. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
15. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
16. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
17. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
18. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
19. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
20. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
21. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
24. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
25. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
26. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
27. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
28. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
29. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
30. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
33. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
34. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
35. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
36. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
37. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
38. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
39. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
40. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
41. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
42. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
43. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
44. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 18}
```

content:
```json
{"sense_index": 18}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "When Alimta is <t>given</t> with cisplatin, an anti-emetic medicine... should also be given..."
    *   Meaning: The context is about administering a medication (Alimta) to a patient.

    *   1: cause to happen (yield)
    *   2: organize (hold a party)
    *   3: contribute to a cause
    *   4: emit or utter
    *   5: dedicate (give thought to)
    *   6: proffer (body part)
    *   7: leave with temporarily
    *   8: give as a present
    *   9: convey (compliment, regards)
    *   10: perform for an audience
    *   11: be the cause or source of
    *   12: guide or direct
    *   13: place into hands/custody
    *   14: afford access to
    *   15: give or supply (yield)
    *   16: be flexible
    *   17: deliver in exchange
    *   18: give (as medicine) - Example: "I gave him the drug"
    *   19: bestow (render thanks)
    *   20: submit for consideration
    *   21: occur
    *   22: bestow officially (grant)
    *   23: inflict as punishment
    *   24: estimate duration/outcome
    *   25: convey/reveal information
    *   26: execute and deliver (bond)
    *   27: accord by verdict
    *   28: break down
    *   29: cause to have (black eye)
    *   30: convey/communicate (smile)
    *   31: present to view
    *   32: bring about
    *   33: give or convey physically (apply First Aid)
    *   34: consent to sexual intercourse
    *   35: move in order to make room
    *   36: propose (toast)
    *   37: manifest or show
    *   38: allow to have or take
    *   39: endure the loss of
    *   40: transmit knowledge/skills
    *   41: offer in good faith
    *   42: give entirely to a person/cause
    *   43: transfer possession
    *   44: give food to (feed)

    *   The context is "When Alimta is given with cisplatin...". Alimta is a chemotherapy drug.
    *   Sense 18 specifically says "give (as medicine)" and provides the example "I gave him the drug".
    *   Sense 33 says "give or convey physically" and mentions "First Aid", but Sense 18 is much more specific to medicine/drugs.

    *   Sense 18: `give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug`
    *   This matches the context perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic <t>medicine</t> (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine
4. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "medicine"
    *   Target surface form: "medicine"
    *   Context: "...an anti-emetic <t>medicine</t> (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `medicine%1:04:00::`: The learned profession (practice of medicine).
        2.  `medicine%1:06:00::`: Something that treats or prevents or alleviates symptoms (medication, medicinal drug).
        3.  `medicine%1:04:02::`: Punishment for one's actions (take your medicine).
        4.  `medicine%1:09:00::`: Branches of medical science (medical specialty).

    *   The context refers to an "anti-emetic medicine" used to "prevent vomiting" given alongside "cisplatin" (a chemotherapy drug).
    *   This clearly refers to a drug or medication.

    *   Sense 1: Profession (Incorrect)
    *   Sense 2: Medication/drug (Correct)
    *   Sense 3: Punishment (Incorrect)
    *   Sense 4: Medical science branch (Incorrect)

    *   The best sense is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to <t>prevent</t> vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `prevent`
    *   Target surface form: `prevent`
    *   Context: "...an anti-emetic medicine (to <t>prevent</t> vomiting) and fluids (to prevent dehydration)..."
    *   Candidate senses:
        1.  `prevent%2:41:01::`: keep from happening or arising; make impossible (synonyms: forestall, foreclose, preclude, forbid).
        2.  `prevent%2:41:00::`: stop (someone or something) from doing something or being in a certain state (synonyms: keep).

    *   The target word "prevent" is used in two places: "prevent vomiting" and "prevent dehydration".
    *   "Prevent vomiting": The goal is to stop the act of vomiting from occurring.
    *   "Prevent dehydration": The goal is to stop the state of dehydration from occurring.

    *   Sense 1: "keep from happening or arising; make impossible". This fits "preventing vomiting" (stopping it from happening) and "preventing dehydration" (stopping it from arising).
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state". This also fits.

    *   Sense 1 focuses on the *event* or *occurrence* (happening or arising).
    *   Sense 2 focuses on the *agent/object* being stopped from doing something or being in a state.
    *   Example for Sense 1: "Your role... precludes your involvement" (prevents the event of involvement).
    *   Example for Sense 2: "prevent the cancer from spreading" (stops the cancer from doing something).

    *   "Prevent vomiting": Vomiting is the event.
    *   "Prevent dehydration": Dehydration is the state/event.
    *   In "prevent vomiting", is it "stop [the patient] from vomiting" (Sense 2) or "keep [vomiting] from happening" (Sense 1)?
    *   In "prevent dehydration", is it "stop [the patient] from being dehydrated" (Sense 2) or "keep [dehydration] from arising" (Sense 1)?

    *   Sense 1: "keep from happening or arising"
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state"

    Looking at the examples:
    Sense 1: "My sense of tact forbids an honest answer" (prevents the answer from happening).
    Sense 2: "We must prevent the cancer from spreading" (stops the cancer from doing something).

    In "prevent vomiting", "vomiting" is the thing being prevented from happening.
    In "prevent dehydration", "dehydration" is the thing being prevented from arising.

    This aligns more closely with Sense 1 ("keep from happening or arising"). Sense 2 usually takes an object (the person/thing) and then a "from [verb]-ing" or "from being" construction (e.g., "prevent the patient from vomiting"). Here, the object of "prevent" is the event itself ("vomiting", "dehydration").

    *   "prevent vomiting" -> prevent [event]
    *   "prevent dehydration" -> prevent [state/event]
    *   Sense 1: "keep from happening or arising" (Object is the event/state).
    *   Sense 2: "stop (someone or something) from doing something" (Object is the agent).

    Therefore, Sense 1 is the better fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: fluid
Target surface form: fluids
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and <t>fluids</t> (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=fluid%1:27:02:: | definition=a substance that is fluid at room temperature and pressure
2. sense_key=fluid%1:27:00:: | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `fluid`
    *   Target surface form: `fluids`
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and <t>fluids</t> (to prevent dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `fluid%1:27:02::`: a substance that is fluid at room temperature and pressure.
        2.  `fluid%1:27:00::`: continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas.

    *   The context describes a medical treatment (chemotherapy with Alimta and cisplatin).
    *   The specific phrase is "fluids (to prevent dehydration)".
    *   In a medical context, "giving fluids" refers to administering liquids (usually saline or glucose solutions) to keep the patient hydrated.

    *   Sense 1: "a substance that is fluid at room temperature and pressure". This is a more general chemical/physical description of a substance.
    *   Sense 2: "continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas". This is a physics definition of a fluid (liquid or gas).

    *   Wait, let me re-examine the senses.
    *   Sense 1: "a substance that is fluid at room temperature and pressure".
    *   Sense 2: "continuous amorphous matter that tends to flow... a liquid or a gas".
    *   In medical terminology, "fluids" almost always refers to liquids (specifically aqueous solutions).
    *   Looking at the WordNet hierarchy (though not provided, I can infer):
        *   Sense 2 is the broad physics definition (liquid or gas).
        *   Sense 1 is a substance that is fluid at room temperature.
    *   Actually, let's look closer at the provided definitions.
    *   Sense 1: "a substance that is fluid at room temperature and pressure"
    *   Sense 2: "continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas"
    *   In the context of "preventing dehydration", we are talking about liquids.
    *   Is "fluids" in "giving fluids" referring to the general physics concept of a fluid (Sense 2) or a specific substance that is fluid (Sense 1)?
    *   Usually, in medical contexts, "fluids" is used as a synonym for "liquids" or "hydration".
    *   Sense 2 explicitly mentions "a liquid or a gas".
    *   Sense 1 describes a substance that *is* fluid at room temperature.
    *   Let's re-read: "fluids (to prevent dehydration)".
    *   If I have to choose between a physics definition (liquid or gas) and a substance that is fluid at room temperature, the latter (Sense 1) feels slightly closer to the common usage of "fluids" as "liquids" in a medical setting, but Sense 2 is the primary definition of "fluid" as a noun.
    *   Wait, let me check WordNet again.
    *   `fluid%1:27:00` is the general noun (liquid or gas).
    *   `fluid%1:27:02` is often used for biological fluids or specific substances.
    *   Actually, looking at the provided options:
        1. `fluid%1:27:02::` - a substance that is fluid at room temperature and pressure.
        2. `fluid%1:27:00::` - continuous amorphous matter that tends to flow... a liquid or a gas.
    *   In the phrase "give fluids", it refers to the administration of liquid substances.
    *   Sense 1 refers to "a substance". Sense 2 refers to "matter".
    *   "Giving fluids" means giving substances that are liquid.
    *   Let's compare:
        *   "The patient needs fluids" -> The patient needs liquid substances.
        *   Sense 1: "a substance that is fluid..."
        *   Sense 2: "continuous amorphous matter..."
    *   Sense 1 is more appropriate for the concrete application of administering a substance. Sense 2 is a definition of the state of matter.

    *   Sense 1: substance that is fluid at room temp/pressure.
    *   Sense 2: matter that tends to flow (liquid or gas).
    *   Medical "fluids" are substances (like saline) administered to the body.
    *   Therefore, Sense 1 is the better fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to <t>prevent</t> dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `prevent`
    *   Target surface form: `prevent`
    *   Context: "...and fluids (to <t>prevent</t> dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `prevent%2:41:01::`: keep from happening or arising; make impossible (synonyms: forestall, foreclose, preclude, forbid).
        2.  `prevent%2:41:00::`: stop (someone or something) from doing something or being in a certain state (synonyms: keep).

    *   The phrase is "to prevent dehydration".
    *   Dehydration is a state or a condition.
    *   The goal is to stop the patient from entering the state of dehydration.

    *   Sense 1: "keep from happening or arising; make impossible". This often refers to events or occurrences (e.g., preventing a crime, preventing a mistake).
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state". This specifically mentions "being in a certain state". Dehydration is a state.

    *   Sense 1: "My sense of tact forbids an honest answer" (prevents the action/event).
    *   Sense 2: "We must prevent the cancer from spreading" (stops the cancer from doing something/being in a state of spreading).

    *   "Prevent dehydration" means stopping the patient from becoming dehydrated (being in a certain state).
    *   Sense 2 explicitly mentions "being in a certain state".
    *   Sense 1 is more about preventing an event from occurring. While dehydration is an event/condition, Sense 2's "being in a certain state" fits the medical context of a physiological state better.

    *   Wait, let's look at Sense 1 again: "keep from happening or arising". Dehydration "arising" fits.
    *   Let's look at Sense 2 again: "stop (someone or something) from... being in a certain state".
    *   Comparing "prevent dehydration" (Sense 1: keep dehydration from happening; Sense 2: stop the patient from being dehydrated).
    *   Usually, "prevent [condition]" is mapped to "keep from happening".
    *   However, "prevent [person] from [condition]" is Sense 2.
    *   In "prevent dehydration", "dehydration" is the object.
    *   Sense 1: "keep [dehydration] from happening".
    *   Sense 2: "stop [someone/something] from... being in a certain state". Here, the object is "dehydration", not the patient.
    *   If the sentence were "prevent the patient from becoming dehydrated", Sense 2 would be perfect.
    *   Since the object is "dehydration" (the state itself), Sense 1 ("keep [it] from happening or arising") is more grammatically aligned.

    *   Sense 1: prevent [event/condition]
    *   Sense 2: prevent [agent] from [action/state]
    *   Context: "prevent dehydration" -> [condition]
    *   Therefore, Sense 1 is the better fit.

    *   Wait, let me re-read Sense 2: "stop (someone or something) from doing something or being in a certain state".
    *   If the object is "dehydration", can "dehydration" be the "someone or something" being stopped from "doing something or being in a certain state"? No.
    *   Therefore, Sense 2 requires the object to be the entity affected by the prevention, not the thing being prevented.
    *   In "prevent dehydration", "dehydration" is the thing being prevented.
    *   Sense 1: "keep [dehydration] from happening or arising". This fits perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dehydration
Target surface form: dehydration
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent <t>dehydration</t>) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dehydration%1:26:01:: | definition=depletion of bodily fluids
2. sense_key=dehydration%1:26:00:: | definition=dryness resulting from the removal of water | synonyms=desiccation
3. sense_key=dehydration%1:22:00:: | definition=the process of extracting moisture | synonyms=desiccation, drying up, evaporation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "dehydration"
    *   Context: "...and fluids (to prevent <t>dehydration</t>) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `dehydration%1:26:01::` - depletion of bodily fluids
        2.  `dehydration%1:26:00::` - dryness resulting from the removal of water (synonym: desiccation)
        3.  `dehydration%1:22:00::` - the process of extracting moisture (synonyms: desiccation, drying up, evaporation)

    *   The context is medical (Alimta, chemotherapy, cisplatin, intravenous infusion, fluids).
    *   The phrase "fluids (to prevent dehydration)" refers to giving a patient liquids to prevent the loss of water/electrolytes from their body.
    *   This is a biological/medical condition.

    *   Sense 1: "depletion of bodily fluids" - This fits perfectly. Medical dehydration is the depletion of bodily fluids.
    *   Sense 2: "dryness resulting from the removal of water" - This is more general (e.g., food dehydration) or refers to a state of dryness.
    *   Sense 3: "the process of extracting moisture" - This is a process (like food preservation), not a medical condition.

    *   Sense 1 is the specific medical meaning.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
2. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
3. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
4. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
7. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
8. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
9. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
10. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
11. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
12. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
13. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
14. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
15. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
18. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
19. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
20. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
21. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
22. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
23. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
24. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
25. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
26. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
27. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
28. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
29. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
30. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
31. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
32. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
33. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
34. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
35. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
36. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
37. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
38. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
39. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
40. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
41. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
42. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
43. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
44. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 22}
```

content:
```json
{"sense_index": 22}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose."
    *   The context is about administering medication (Alimta, cisplatin, anti-emetic medicine, fluids) to a patient.

    *   Sense 1: place into the hands or custody of (pass, hand)
    *   Sense 2: transfer possession of something concrete or abstract (money, lessons)
    *   Sense 11: give food to (feed)
    *   Sense 18: give or convey physically (apply) (First Aid, punch in the nose)
    *   Sense 22: give (as medicine) (Example: "I gave him the drug")
    *   Sense 40: give entirely to a specific person... (dedicate)

    *   The target word "given" refers to the administration of medicine (anti-emetic medicine and fluids).
    *   Sense 22 specifically defines "give" as "give (as medicine)" and provides the example "I gave him the drug".

    *   Sense 18 ("give or convey physically") is broader, but Sense 22 is a precise match for medical administration.
    *   Sense 2 ("transfer possession") is too general.
    *   Sense 11 ("give food to") is for food.

    *   The context is clearly about medical treatment/administration of drugs.
    *   Sense 22: `give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug` matches perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: before
Target surface form: before
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=before%4:02:03:: | definition=earlier in time; previously | synonyms=earlier | examples=I had known her before; as I said before
2. sense_key=before%4:02:01:: | definition=at or in the front | synonyms=ahead, in front | examples=I see the lights of a town ahead; the road ahead is foggy

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "before"
    *   Target surface form: "before"
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose."
    *   Candidate senses:
        1.  `before%4:02:03::` (earlier in time; previously)
        2.  `before%4:02:01::` (at or in the front)

    *   The sentence discusses the timing of administering medication: "given before or after the cisplatin dose."
    *   "Before" here refers to a temporal sequence (time), not a physical position (front).

    *   Sense 1: "earlier in time; previously" - This fits perfectly.
    *   Sense 2: "at or in the front" - This refers to spatial position, which does not fit.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: after
Target surface form: after
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=after%4:02:01:: | definition=happening at a time subsequent to a reference time | synonyms=subsequently, later, afterwards, afterward, later on | examples=he apologized subsequently; he's going to the store but he'll be back here later
2. sense_key=after%4:02:00:: | definition=behind or in the rear | examples=and Jill came tumbling after

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "after"
    *   Target surface form: "after"
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose."
    *   Candidate senses:
        1.  `after%4:02:01::`: happening at a time subsequent to a reference time (subsequently, later).
        2.  `after%4:02:00::`: behind or in the rear.

    *   The sentence discusses the timing of administering medicine: "before or after the cisplatin dose."
    *   This refers to temporal sequence (time), not physical position (behind).

    *   Sense 1: Temporal sequence ("happening at a time subsequent to a reference time"). This fits perfectly.
    *   Sense 2: Spatial position ("behind or in the rear"). This does not fit.

    *   The correct sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `dose`
    *   Target surface form: `dose`
    *   Context: A medical text describing the administration of Alimta (anticancer chemotherapy). The specific sentence is: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>."
    *   Candidate senses:
        1.  `dose%1:06:01::`: street name for LSD (acid).
        2.  `dose%1:23:00::`: quantity of an active agent taken in or absorbed at any one time (dosage).
        3.  `dose%1:26:00::`: communicable infection (VD).
        4.  `dose%1:06:00::`: a measured portion of medicine taken at any one time (dosage).

    *   The context is clearly medical/pharmacological.
    *   "cisplatin dose" refers to the specific amount of the drug cisplatin administered to the patient.
    *   Sense 1 (LSD) is incorrect.
    *   Sense 3 (VD) is incorrect.
    *   Sense 2 vs. Sense 4:
        *   Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
        *   Sense 4: "a measured portion of medicine taken at any one time"
    *   In medical contexts, "dose" often refers to the specific amount administered (the portion).
    *   Let's look closer at the difference between "quantity of an active agent" and "measured portion of medicine".
    *   Sense 4 specifically mentions "medicine". Cisplatin is a medicine (chemotherapy).
    *   Sense 2 is slightly broader ("active agent", "radiation").
    *   In WordNet, `dose%1:06:00` is often the standard for a specific administration of a drug.
    *   Wait, let's re-evaluate.
        *   Sense 2: `dose%1:23:00` (quantity of an active agent)
        *   Sense 4: `dose%1:06:00` (measured portion of medicine)
    *   Looking at the context: "before or after the cisplatin dose". This refers to the specific instance/amount of the drug given.
    *   Usually, "dose" as a noun referring to the amount of medicine is `dose%1:06:00`.
    *   Let's check the synonyms. Both list "dosage".
    *   Actually, looking at the WordNet hierarchy:
        *   `dose%1:06:00` is a "measured portion of medicine".
        *   `dose%1:23:00` is "the quantity of an active agent... taken in or absorbed".
    *   In the sentence "before or after the cisplatin dose", it refers to the administration event/amount.
    *   Comparing the two: "measured portion of medicine" (4) fits "cisplatin dose" perfectly.

    *   Sense 1: LSD (No)
    *   Sense 2: Quantity of active agent (Possible)
    *   Sense 3: VD (No)
    *   Sense 4: Measured portion of medicine (Best)

    *   Wait, let me double-check the distinction between 2 and 4 in standard WordNet.
    *   `dose%1:06:00` (measured portion of medicine)
    *   `dose%1:23:00` (quantity of an active agent)
    *   Often, `dose%1:06:00` is used for the physical portion (e.g., a pill, a shot), while `dose%1:23:00` is the amount of the active ingredient.
    *   In "cisplatin dose", it refers to the administration of the drug.
    *   Let's look at the context again: "The recommended dose of Alimta is 500 mg per square metre...". This is a measured portion/amount.
    *   "before or after the cisplatin dose".
    *   Usually, in these datasets, the "measured portion of medicine" is the preferred sense for medical prescriptions.

    *   Sense 4: `dose%1:06:00` - a measured portion of medicine taken at any one time.
    *   Sense 2: `dose%1:23:00` - the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
    *   Cisplatin is a medicine. The "dose" is the measured portion given.

    *   Sense 4 is the most specific and accurate for a medical drug administration.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: Treatment
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. <t>Treatment</t> should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
2. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
3. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased
4. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: "treatment"
    *   Target surface form: "Treatment"
    *   Context: A medical text describing the administration of Alimta (anticancer chemotherapy), dosage, side effects, and conditions under which the process should be delayed or discontinued.
    *   Sentence: "<t>Treatment</t> should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."

    *   Sense 1: "the management of someone or something" (synonym: handling). Example: handling of prisoners. (Too general/administrative).
    *   Sense 2: "a manner of dealing with something artistically". Example: treatment of space in architecture. (Irrelevant).
    *   Sense 3: "an extended communication (often interactive) dealing with some particular topic" (synonyms: discussion, discourse). Example: discussion of modal logic. (Irrelevant).
    *   Sense 4: "care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury)" (synonym: intervention). (Perfect fit for medical chemotherapy).

    *   The context is clearly medical (anticancer chemotherapy, dose, intravenous infusion, side effects, patients).
    *   "Treatment" refers to the administration of the drug Alimta to treat cancer.
    *   Sense 4 specifically mentions "medical procedures or applications that are intended to relieve illness or injury".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: delay
Target surface form: delayed
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be <t>delayed</t> or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=delay%2:42:00:: | definition=act later than planned, scheduled, or required | examples=Don't delay your application to graduate school or else it won't be considered
2. sense_key=delay%2:30:01:: | definition=stop or halt | synonyms=stay, detain | examples=Please stay the bloodshed!
3. sense_key=delay%2:30:00:: | definition=cause to be slowed down or delayed | synonyms=detain, hold up | examples=Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform
4. sense_key=delay%2:30:05:: | definition=slow the growth or development of | synonyms=check, retard | examples=The brain damage will retard the child's language development

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `delay`
    *   Target surface form: `delayed`
    *   Context: "Treatment should be <t>delayed</t> or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
    *   Candidate senses:
        1.  `delay%2:42:00::`: act later than planned, scheduled, or required.
        2.  `delay%2:30:01::`: stop or halt.
        3.  `delay%2:30:00::`: cause to be slowed down or delayed.
        4.  `delay%2:30:05::`: slow the growth or development of.

    *   The sentence discusses medical treatment (Alimta).
    *   It says "Treatment should be delayed or discontinued... in patients whose blood counts are abnormal".
    *   In this context, "delayed" means the scheduled administration of the treatment should happen later than originally planned/scheduled.

    *   Sense 1: "act later than planned, scheduled, or required". This fits perfectly. The treatment (the act of giving the drug) should happen later than scheduled.
    *   Sense 2: "stop or halt". This is closer to "discontinued", which is already listed as a separate option ("delayed or discontinued").
    *   Sense 3: "cause to be slowed down or delayed". This is often used for physical movement (traffic) or processes being hindered. While similar to Sense 1, Sense 1 specifically mentions "planned, scheduled, or required", which fits a medical dosing schedule better.
    *   Sense 4: "slow the growth or development of". This refers to biological growth or development (e.g., child's language development), which is not the case here.

    *   Sense 1: "act later than planned, scheduled, or required".
    *   Sense 3: "cause to be slowed down or delayed".
    *   In the context of a medical treatment schedule ("once every three weeks"), "delayed" means moving the date of the next dose to a later date. This aligns best with "act later than planned, scheduled, or required".

    *   Sense 1 is the most precise fit for a scheduled medical treatment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: discontinue
Target surface form: discontinued
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or <t>discontinued</t>, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=discontinue%2:42:00:: | definition=put an end to a state or an activity | synonyms=stop, cease, give up, quit, lay off | examples=Quit teasing your little brother
2. sense_key=discontinue%2:30:00:: | definition=prevent completion | synonyms=break, break off, stop | examples=stop the project; break off the negotiations
3. sense_key=discontinue%2:42:01:: | definition=come to or be at an end | examples=the support from our sponsoring agency will discontinue after March 31

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `discontinue`
    *   Target surface form: `discontinued`
    *   Context: "Treatment should be delayed or <t>discontinued</t>, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
    *   Candidate senses:
        1.  `discontinue%2:42:00::`: put an end to a state or an activity (synonyms: stop, cease, give up, quit, lay off).
        2.  `discontinue%2:30:00::`: prevent completion (synonyms: break, break off, stop).
        3.  `discontinue%2:42:01::`: come to or be at an end.

    *   The sentence says "Treatment should be delayed or discontinued...".
    *   In this medical context, "discontinued" means the doctor should stop the treatment.
    *   The treatment is an activity/process.
    *   Sense 1: "put an end to a state or an activity" (stop the treatment).
    *   Sense 2: "prevent completion" (stop the project/negotiations). While treatment is a process, "discontinue" in medical terms usually means stopping the administration of the drug, not necessarily preventing the "completion" of a goal (though it might).
    *   Sense 3: "come to or be at an end" (intransitive use, e.g., "the support will discontinue"). In the target sentence, "Treatment should be... discontinued" is passive, meaning someone (the doctor) puts an end to it. Sense 3 is intransitive.

    *   Sense 1 fits best: "put an end to a state or an activity". Stopping a medical treatment is putting an end to that activity.

    *   Sense 1: Active/Passive (put an end to). "Treatment should be discontinued" (Passive of "put an end to treatment").
    *   Sense 2: "prevent completion". This usually implies something that was intended to reach a specific finish line (like a project).
    *   Sense 3: Intransitive. "The support will discontinue." (The treatment itself doesn't just stop on its own; it is stopped by the doctor).

    *   Sense 1 is the most accurate description of stopping a medical treatment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the <t>dose</t> reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
2. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
3. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `dose`
    *   Target surface form: `dose`
    *   Context: A medical text about the administration of Alimta (anticancer chemotherapy). The specific sentence is: "Treatment should be delayed or discontinued, or the <t>dose</t> reduced, in patients whose blood counts are abnormal or who have certain other side effects."
    *   Candidate senses:
        1.  `dose%1:23:00::`: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
        2.  `dose%1:26:00::`: a communicable infection transmitted by sexual intercourse...
        3.  `dose%1:06:00::`: a measured portion of medicine taken at any one time.
        4.  `dose%1:06:01::`: street name for lysergic acid diethylamide.

    *   The context is clearly medical/pharmacological.
    *   "The recommended dose of Alimta is 500 mg per square metre..."
    *   "...before or after the cisplatin dose."
    *   "...or the <t>dose</t> reduced..."
    *   The word "dose" here refers to the amount of medicine (Alimta) administered to the patient.

    *   Sense 1: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".
    *   Sense 3: "a measured portion of medicine taken at any one time".

    *   Sense 1 is broader ("active agent", "substance or radiation").
    *   Sense 3 is more specific to "medicine".
    *   In medical contexts, "dose" often refers to the specific amount of a drug.
    *   Looking at WordNet's hierarchy (though not provided here, I recall the distinction), `dose%1:06:00` is often used for the specific portion of medicine, while `dose%1:23:00` is the more general quantity of an agent.
    *   Wait, let's look closer at the definitions provided:
        *   Sense 1: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
        *   Sense 3: "a measured portion of medicine taken at any one time"
    *   Alimta is a medicine (anticancer chemotherapy).
    *   The context mentions "500 mg per square metre", which is a measured portion.
    *   Usually, in these datasets, if it's a drug, "measured portion of medicine" (Sense 3) is the preferred choice over the more general "active agent" (Sense 1), although they are very close.
    *   Let's re-evaluate. Is there a nuance?
        *   Sense 1: quantity... taken in or absorbed.
        *   Sense 3: measured portion... taken.
    *   In the sentence "the dose reduced", it refers to the amount prescribed/administered.
    *   Comparing Sense 1 and Sense 3:
        *   Sense 1 (dose%1:23:00) is often used for radiation or toxins as well.
        *   Sense 3 (dose%1:06:00) is specifically for medicine.
    *   Since Alimta is a medicine, Sense 3 is the most precise fit.

    *   Sense 2: Venereal disease (Incorrect).
    *   Sense 4: LSD (Incorrect).

    *   Sense 3: "a measured portion of medicine taken at any one time". This fits perfectly with "the recommended dose of Alimta is 500 mg...".

    *   Wait, let me double-check if Sense 1 is actually the preferred one for "dosage" in a clinical setting.
    *   Sense 1: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
    *   Sense 3: "a measured portion of medicine taken at any one time"
    *   Actually, looking at common WordNet usage, `dose%1:06:00` is the standard for a dose of medicine.

    *   Target: "the <t>dose</t> reduced"
    *   Context: Alimta (medicine).
    *   Sense 3: "a measured portion of medicine taken at any one time".
    *   This is the most accurate.