[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: part
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also <t>part</t> of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
2. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
3. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
4. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
5. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
6. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
7. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
8. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
9. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work
10. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
11. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
12. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 7}
```

content:
```json
{"sense_index": 7}
```

reasoning_content:
*   Target lemma: "part"
    *   Target surface form: "part"
    *   Context: "...read the Scientific Discussion (also <t>part</t> of the EPAR)."
    *   Meaning: The "Scientific Discussion" is a component or a section of the "European Public Assessment Report (EPAR)".

    *   1: portion of a natural object (No)
    *   2: line of scalp (No)
    *   3: melody in polyphonic music (No)
    *   4: extended spatial location (No)
    *   5: something less than the whole of a human artifact (Possible, but usually refers to physical parts like "rear part of the house")
    *   6: concerns a person with regard to a role (No)
    *   7: one of the portions into which something is regarded as divided and which together constitute a whole (Synonyms: section, division. Example: "the written part of the exam"). (Strong candidate)
    *   8: something determined in relation to something that includes it (Synonyms: portion, component part, constituent. Example: "feel a part of something bigger"). (Strong candidate)
    *   9: part played by a person in bringing about a result (No)
    *   10: actions/activities assigned to a person (No)
    *   11: assets belonging to a person (No)
    *   12: actor's portrayal (No)

    *   Sense 7: "one of the portions into which something is regarded as divided and which together constitute a whole" (Synonyms: section, division).
    *   Sense 8: "something determined in relation to something that includes it" (Synonyms: portion, component part, constituent).

    The "Scientific Discussion" is a specific section or division of the EPAR document. Sense 7's example "the written part of the exam" is very similar to "the Scientific Discussion part of the EPAR". Sense 8 is often used for membership or abstract belonging ("part of the team", "part of the problem").

    Let's re-examine Sense 7: "one of the portions into which something is regarded as divided and which together constitute a whole". This fits a document structure perfectly.

    Let's re-examine Sense 5: "something less than the whole of a human artifact". A document is a human artifact. However, Sense 7 is more specific to divisions/sections of a whole.

    Comparing 7 and 8 again:
    7: section, division.
    8: component part, constituent.

    In the context of a report (EPAR), the "Scientific Discussion" is a section or division of that report.

    Sense 7: "the written part of the exam" -> "the Scientific Discussion part of the EPAR".
    Sense 8: "I read a portion of the manuscript" -> "the Scientific Discussion is a part of the EPAR".

    Wait, Sense 8's example "I read a portion of the manuscript" is very close. But Sense 7's "section, division" is the most precise description for a specific named part of a formal document.

    Let's look at the phrasing: "read the Scientific Discussion (also part of the EPAR)".
    This means the Scientific Discussion is one of the sections that make up the EPAR.

    Sense 7: "one of the portions into which something is regarded as divided and which together constitute a whole".
    Sense 8: "something determined in relation to something that includes it".

    Sense 7 is the best fit for a section of a document.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: powder
Target surface form: powder
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a <t>powder</t> that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=powder%1:27:00:: | definition=a solid substance in the form of tiny loose particles; a solid that has been pulverized | synonyms=pulverization, pulverisation
2. sense_key=powder%1:27:01:: | definition=a mixture of potassium nitrate, charcoal, and sulfur in a 75:15:10 ratio which is used in gunnery, time fuses, and fireworks | synonyms=gunpowder
3. sense_key=powder%1:06:01:: | definition=any of various cosmetic or medical preparations dispensed in the form of a pulverized powder

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

finish_reason: stop

content:
```json
{"sense_index": 3}
```

role: assistant

reasoning_content:
*   Target lemma: `powder`
    *   Target surface form: `powder`
    *   Context: "Alimta is a <t>powder</t> that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed."
    *   Candidate senses:
        1.  `powder%1:27:00::`: a solid substance in the form of tiny loose particles; a solid that has been pulverized.
        2.  `powder%1:27:01::`: a mixture of potassium nitrate, charcoal, and sulfur... (gunpowder).
        3.  `powder%1:06:01::`: any of various cosmetic or medical preparations dispensed in the form of a pulverized powder.

    *   The context describes "Alimta", which is a medicine (active substance pemetrexed) used for infusion.
    *   It is described as a "powder" that is then made into a solution.
    *   This is clearly a medical preparation.

    *   Sense 1 is a general definition of powder (tiny loose particles).
    *   Sense 2 is gunpowder.
    *   Sense 3 is specifically for "cosmetic or medical preparations dispensed in the form of a pulverized powder".

    *   While Sense 1 is technically correct (it is a solid substance in the form of tiny particles), Sense 3 is more specific and fits the context of a medicine (Alimta) perfectly. In fine-grained WSD, the most specific correct sense is usually preferred.

    *   Target: Alimta (medicine)
    *   Form: powder
    *   Sense 3: medical preparations dispensed in the form of a pulverized powder.
    *   Match: High.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: solution
Target surface form: solution
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a <t>solution</t> for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=solution%1:04:00:: | definition=the successful action of solving a problem | examples=the solution took three hours
2. sense_key=solution%1:14:00:: | definition=the set of values that give a true statement when substituted into an equation | synonyms=root
3. sense_key=solution%1:27:00:: | definition=a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution | examples=he used a solution of peroxide and water
4. sense_key=solution%1:09:00:: | definition=a method for solving a problem | examples=the easy solution is to look it up in the handbook
5. sense_key=solution%1:10:00:: | definition=a statement that solves a problem or explains how to solve the problem | synonyms=answer, result, resolution, solvent | examples=they were trying to find a peaceful solution; the answers were in the back of the book

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `solution`
    *   Target surface form: `solution`
    *   Context: "Alimta is a powder that is made up into a <t>solution</t> for infusion (drip into a vein)."
    *   Candidate senses:
        1.  `solution%1:04:00::`: successful action of solving a problem.
        2.  `solution%1:14:00::`: set of values for an equation (root).
        3.  `solution%1:27:00::`: homogeneous mixture of two or more substances (liquid).
        4.  `solution%1:09:00::`: method for solving a problem.
        5.  `solution%1:10:00::`: statement that solves a problem (answer).

    *   The context describes a medicine (Alimta) which is a powder that is "made up into a solution for infusion (drip into a vein)".
    *   In a medical/chemical context, a "solution for infusion" refers to a liquid mixture where a solute (the powder) is dissolved in a solvent.

    *   Sense 1: Solving a problem (Incorrect).
    *   Sense 2: Mathematical root (Incorrect).
    *   Sense 3: Homogeneous mixture of two or more substances (Correct).
    *   Sense 4: Method for solving a problem (Incorrect).
    *   Sense 5: Statement/answer to a problem (Incorrect).

    *   Sense 3 matches the chemical/medical meaning of a liquid mixture.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for <t>infusion</t> (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
2. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent
3. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)
4. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "infusion"
    *   Target surface form: "infusion"
    *   Context: "Alimta is a powder that is made up into a solution for <t>infusion</t> (drip into a vein)."
    *   Candidate senses:
        1.  `infusion%1:27:00::`: a solution obtained by steeping or soaking a substance (usually in water) (e.g., tea).
        2.  `infusion%1:04:01::`: the act of infusing or introducing a certain modifying element or quality (e.g., new talent).
        3.  `infusion%1:04:00::`: (medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force).
        4.  `infusion%1:22:00::`: the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water).

    *   The context explicitly mentions "solution for infusion (drip into a vein)".
    *   This is a medical context involving the administration of a drug (Alimta/pemetrexed) into a vein.

    *   Sense 1: Steeping/soaking (like tea). Not applicable.
    *   Sense 2: Introducing a quality/element (metaphorical). Not applicable.
    *   Sense 3: Medical introduction of a substance into a vein. This matches perfectly ("drip into a vein").
    *   Sense 4: Process of extracting properties by steeping. Not applicable.

    *   The best sense is sense 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: drip
Target surface form: drip
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (<t>drip</t> into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=drip%2:35:10:: | definition=let or cause to fall in drops | synonyms=dribble, drop | examples=dribble oil into the mixture
2. sense_key=drip%2:38:00:: | definition=fall in drops | examples=Water is dripping from the faucet

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `drip`
    *   Target surface form: `drip`
    *   Context: "...Alimta is a powder that is made up into a solution for infusion (<t>drip</t> into a vein)."
    *   Candidate senses:
        1.  `drip%2:35:10::`: let or cause to fall in drops (transitive/causative)
        2.  `drip%2:38:00::`: fall in drops (intransitive)

    *   The phrase is "solution for infusion (drip into a vein)".
    *   In this context, "drip" is used as a verb describing the action of the solution being administered.
    *   "Infusion" implies the process of introducing a fluid into a vein.
    *   The phrase "(drip into a vein)" acts as a parenthetical explanation of "infusion".
    *   Is it "let or cause to fall in drops" (Sense 1) or "fall in drops" (Sense 2)?
    *   An infusion is a process where the medicine is *caused* to fall/flow into the vein (usually via a drip system).
    *   However, looking at the grammar: "solution for infusion (drip into a vein)". This is slightly elliptical. It likely means "[to] drip into a vein" or "[which is] dripped into a vein".
    *   If it's "to drip into a vein", it describes the action of the liquid.
    *   Sense 1: "let or cause to fall in drops" (transitive). Example: "dribble oil into the mixture".
    *   Sense 2: "fall in drops" (intransitive). Example: "Water is dripping from the faucet".
    *   In "drip into a vein", the subject is the solution. The solution falls in drops into the vein.
    *   Wait, let's re-read. "solution for infusion (drip into a vein)".
    *   If the solution is the subject, it "drips" (falls in drops).
    *   If the medical professional is the implied subject, they "drip" (cause to fall) the solution.
    *   Usually, in medical contexts, "a drip" (noun) is the apparatus, but here it's used as a verb.
    *   "Infusion (drip into a vein)" -> The solution is infused, meaning it is made to drip into the vein.
    *   Let's compare the senses again.
        *   Sense 1: let or cause to fall in drops.
        *   Sense 2: fall in drops.
    *   In the phrase "drip into a vein", the solution is the thing doing the dripping. "The solution drips into the vein." This is the intransitive use (Sense 2).
    *   However, "infusion" is the act of introducing. The parenthetical "(drip into a vein)" explains the infusion.
    *   If I say "I will drip the medicine into the vein", that's Sense 1.
    *   If I say "The medicine will drip into the vein", that's Sense 2.
    *   The context "solution for infusion (drip into a vein)" suggests the action the solution undergoes or the method of administration.
    *   Looking at the examples:
        *   Sense 1: "dribble oil into the mixture" (Someone is doing the action to the oil).
        *   Sense 2: "Water is dripping from the faucet" (The water is doing the action).
    *   In "solution for infusion (drip into a vein)", the "drip" refers to the process of the liquid falling.
    *   Actually, "infusion" is the noun. "(drip into a vein)" is an appositive or a clarifying phrase. It's most likely shorthand for "[which is] dripped into a vein" or "[to] drip into a vein".
    *   If it's "to drip", it's the liquid dripping.
    *   Let's check if "drip" can be used transitively in a medical sense. Yes, "to drip a patient" or "to drip a solution".
    *   But "drip into a vein" sounds more like the movement of the fluid.
    *   Let's re-evaluate Sense 1: "let or cause to fall in drops".
    *   If the phrase is "solution for infusion (drip into a vein)", it's explaining what "infusion" means. Infusion is the act of *causing* the fluid to enter the vein.
    *   Wait, "drip into a vein" is a very common way to describe the action of the fluid.
    *   Let's look at the senses again.
        *   1: let or cause to fall in drops.
        *   2: fall in drops.
    *   If the solution is the subject, it's Sense 2.
    *   If the administrator is the subject, it's Sense 1.
    *   In "solution for infusion (drip into a vein)", the implied subject of "drip" is the solution. "A solution for infusion (which drips into a vein)".
    *   Therefore, Sense 2 is more likely.

    *   Wait, let me think about this again. "Infusion" is the process. The parenthetical "(drip into a vein)" describes that process.
    *   Is "drip" here a verb or a noun?
    *   "solution for infusion (drip into a vein)"
    *   If it were a noun, it would be "a drip into a vein". But "drip" is not preceded by "a".
    *   If it's a verb, it's likely an infinitive: "(to) drip into a vein".
    *   "The solution is for infusion (to drip into a vein)."
    *   In this case, the solution is the thing that drips.
    *   Sense 2: "fall in drops".
    *   Sense 1: "let or cause to fall in drops".
    *   If the solution is the subject, it's Sense 2.

    *   Let's double-check. Could "drip" be a transitive verb here? "Infusion (drip [the solution] into a vein)". This seems less likely than the solution being the subject.

    *   Let's look at the examples again.
        *   Sense 1: "dribble oil into the mixture" (Transitive: Subject causes oil to fall).
        *   Sense 2: "Water is dripping from the faucet" (Intransitive: Water falls).
    *   "Solution for infusion (drip into a vein)". The solution is the thing falling.

    *   Wait, let me search for this specific phrase in medical texts. "Infusion (drip into a vein)" is often used in patient information leaflets.
    *   In these contexts, "drip" is often used as a shorthand for the process.
    *   If I have to choose between "cause to fall" and "fall", and the subject is the solution, "fall" (Sense 2) is the correct linguistic fit for the intransitive use.

    *   Let's re-read the context one more time. "Alimta is a powder that is made up into a solution for infusion (drip into a vein)."
    *   It's almost certainly describing the action of the solution.

    *   Sense 1: let or cause to fall in drops.
    *   Sense 2: fall in drops.
    *   If the solution is the subject: "The solution drips into a vein." (Sense 2).
    *   If the doctor is the subject: "The doctor drips the solution into a vein." (Sense 1).
    *   The phrase "(drip into a vein)" is modifying "infusion" or "solution". It's describing the nature of the infusion. The infusion is the process of the solution dripping into the vein.
    *   This points toward Sense 2.

    *   Wait, let me consider if "drip" could be a noun here. "a solution for infusion (drip into a vein)". No, that doesn't make grammatical sense. It would be "a drip".
    *   Could it be an imperative? "Infusion (drip [it] into a vein)". Unlikely in a summary document.
    *   It's most likely an infinitive: "(to) drip into a vein".
    *   And the thing that drips is the solution.

    *   Final check:
        *   Sense 1: cause to fall (transitive)
        *   Sense 2: fall (intransitive)
        *   "Solution... (drip into a vein)" -> Solution falls in drops into a vein.
        *   Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: vein
Target surface form: vein
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a <t>vein</t>). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=vein%1:10:00:: | definition=a distinctive style or manner | examples=he continued in this vein for several minutes
2. sense_key=vein%1:17:00:: | definition=a layer of ore between layers of rock | synonyms=mineral vein
3. sense_key=vein%1:20:00:: | definition=any of the vascular bundles or ribs that form the branching framework of conducting and supporting tissues in a leaf or other plant organ | synonyms=nervure
4. sense_key=vein%1:08:00:: | definition=a blood vessel that carries blood from the capillaries toward the heart | synonyms=vena, venous blood vessel | examples=all veins except the pulmonary vein carry unaerated blood
5. sense_key=vein%1:05:00:: | definition=one of the horny ribs that stiffen and support the wing of an insect | synonyms=nervure

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `vein`
    *   Target surface form: `vein`
    *   Context: "...Alimta is a powder that is made up into a solution for infusion (drip into a <t>vein</t>)."
    *   Candidate senses:
        1.  `vein%1:10:00::`: distinctive style or manner.
        2.  `vein%1:17:00::`: layer of ore between layers of rock.
        3.  `vein%1:20:00::`: vascular bundles in a leaf/plant.
        4.  `vein%1:08:00::`: blood vessel carrying blood toward the heart.
        5.  `vein%1:05:00::`: horny ribs in an insect wing.

    *   The context mentions "solution for infusion (drip into a vein)".
    *   "Infusion" in a medical context refers to the administration of fluids or medication directly into a blood vessel.
    *   "Drip into a vein" clearly refers to the anatomical blood vessel.

    *   Sense 1: Style/manner (Incorrect)
    *   Sense 2: Ore/rock (Incorrect)
    *   Sense 3: Plant tissue (Incorrect)
    *   Sense 4: Blood vessel (Correct)
    *   Sense 5: Insect wing (Incorrect)

    *   The best sense is sense 4.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: contain
Target surface form: contains
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It <t>contains</t> the active substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=contain%2:42:06:: | definition=be divisible by | examples=24 contains 6
2. sense_key=contain%2:42:14:: | definition=be capable of holding or containing | synonyms=take, hold | examples=This box won't take all the items; The flask holds one gallon
3. sense_key=contain%2:42:13:: | definition=contain or hold; have within | synonyms=hold, bear, carry | examples=The jar carries wine; The canteen holds fresh water
4. sense_key=contain%2:33:00:: | definition=hold back, as of a danger or an enemy; check the expansion or influence of | synonyms=check, turn back, arrest, stop, hold back | examples=Arrest the downward trend; Check the growth of communism in South East Asia
5. sense_key=contain%2:41:00:: | definition=lessen the intensity of; temper; hold in restraint; hold or keep within limits | synonyms=control, hold in, hold, check, curb, moderate | examples=moderate your alcohol intake; hold your tongue
6. sense_key=contain%2:42:00:: | definition=include or contain; have as a component | synonyms=incorporate, comprise | examples=A totally new idea is comprised in this paper; The record contains many old songs from the 1930's

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `contain`
    *   Target surface form: `contains`
    *   Context: "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It <t>contains</t> the active substance pemetrexed."
    *   Meaning: The medicine (Alimta) has pemetrexed as one of its ingredients/components.

    *   Sense 1: `be divisible by` (Math) - Incorrect.
    *   Sense 2: `be capable of holding or containing` (Capacity) - Incorrect.
    *   Sense 3: `contain or hold; have within` (Physical containment, like a jar holding wine) - Possible, but usually refers to a container and its contents.
    *   Sense 4: `hold back, as of a danger or an enemy` (Restrain) - Incorrect.
    *   Sense 5: `lessen the intensity of; temper` (Control) - Incorrect.
    *   Sense 6: `include or contain; have as a component` (Composition/Ingredients) - Correct.

    *   Sense 3 is about a container holding something (e.g., "The jar carries wine").
    *   Sense 6 is about composition or components (e.g., "The record contains many old songs", "have as a component").
    *   In the context "It contains the active substance pemetrexed", the medicine is not just a container for the substance; the substance is a component of the medicine.

    *   Sense 6: `include or contain; have as a component`. This fits perfectly for a chemical composition or a medicine's active ingredient.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: active
Target surface form: active
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the <t>active</t> substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=active%5:00:00:existent:00 | definition=in operation | synonyms=alive | examples=keep hope alive; the tradition was still alive
2. sense_key=active%3:00:04:: | definition=(of e.g. volcanos) erupting or liable to erupt | examples=active volcanos
3. sense_key=active%3:00:08:: | definition=engaged in full-time work | examples=active duty; though past retirement age he is still active in his profession
4. sense_key=active%3:00:02:: | definition=tending to become more severe or wider in scope | examples=active tuberculosis
5. sense_key=active%3:00:09:: | definition=expressing that the subject of the sentence has the semantic function of actor: | examples=Hemingway favors active constructions
6. sense_key=active%3:00:07:: | definition=exerting influence or producing a change or effect | examples=an active ingredient
7. sense_key=active%3:00:05:: | definition=(of e.g. volcanos) capable of erupting
8. sense_key=active%5:00:00:involved:00 | definition=taking part in an activity | synonyms=participating | examples=an active member of the club; he was politically active
9. sense_key=active%3:00:03:: | definition=disposed to take action or effectuate change | examples=a director who takes an active interest in corporate operations; an active antagonism
10. sense_key=active%3:00:06:: | definition=full of activity or engaged in continuous activity | examples=an active seaport; an active bond market
11. sense_key=active%5:00:00:operational:00 | definition=engaged in or ready for military or naval operations | synonyms=combat-ready, fighting | examples=on active duty; the platoon is combat-ready
12. sense_key=active%3:00:00:: | definition=(used of verbs (e.g. `to run') and participial adjectives (e.g. `running' in `running water')) expressing action rather than a state of being | synonyms=dynamic
13. sense_key=active%3:00:01:: | definition=characterized by energetic activity | examples=an active toddler; active as a gazelle
14. sense_key=active%3:00:10:: | definition=(of the sun) characterized by an increased occurrence of sunspots and flares and radio emissions

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `active`
    *   Target surface form: `active`
    *   Context: "It contains the <t>active</t> substance pemetrexed."
    *   Domain: Medical/Pharmaceutical (discussing a medicine called Alimta).

    *   1: in operation (alive) - No.
    *   2: (volcanos) erupting - No.
    *   3: engaged in full-time work - No.
    *   4: tending to become more severe (e.g., active tuberculosis) - No.
    *   5: grammatical subject as actor - No.
    *   6: exerting influence or producing a change or effect (example: "an active ingredient") - Yes.
    *   7: (volcanos) capable of erupting - No.
    *   8: taking part in an activity (participating) - No.
    *   9: disposed to take action - No.
    *   10: full of activity (e.g., seaport) - No.
    *   11: military/naval operations - No.
    *   12: verbs expressing action rather than state - No.
    *   13: characterized by energetic activity (e.g., toddler) - No.
    *   14: (sun) sunspots/flares - No.

    *   The context is "active substance pemetrexed".
    *   In pharmacology, an "active substance" or "active ingredient" is the component of a drug that produces the intended biological effect.
    *   Sense 6 specifically defines "active" as "exerting influence or producing a change or effect" and provides the example "an active ingredient". This matches perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: substance
Target surface form: substance
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active <t>substance</t> pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=substance%1:09:00:: | definition=the idea that is intended | synonyms=meaning | examples=What is the meaning of this proverb?
2. sense_key=substance%1:03:01:: | definition=a particular kind or species of matter with uniform properties | examples=shigella is one of the most toxic substances known to man
3. sense_key=substance%1:09:01:: | definition=the choicest or most essential or most vital part of some idea or experience | synonyms=kernel, core, center, centre, essence, gist | examples=the gist of the prosecutor's argument; the heart and soul of the Republican Party
4. sense_key=substance%1:03:00:: | definition=the real physical matter of which a person or thing consists | examples=DNA is the substance of our genes
5. sense_key=substance%1:10:00:: | definition=what a communication that is about something is about | synonyms=message, content, subject matter
6. sense_key=substance%1:27:00:: | definition=material of a particular kind or constitution | examples=the immune response recognizes invading substances
7. sense_key=substance%1:21:00:: | definition=considerable capital (wealth or income) | synonyms=means | examples=he is a man of means

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `substance`
    *   Target surface form: `substance`
    *   Context: "It contains the active <t>substance</t> pemetrexed."
    *   Domain: Medical/Pharmaceutical (EPAR, CHMP, medicine, solution for infusion).

    *   Sense 1: `substance%1:09:00::` - the idea that is intended (meaning). (Incorrect)
    *   Sense 2: `substance%1:03:01::` - a particular kind or species of matter with uniform properties. (Possible)
    *   Sense 3: `substance%1:09:01::` - the choicest or most essential part of some idea or experience (kernel, core). (Incorrect)
    *   Sense 4: `substance%1:03:00::` - the real physical matter of which a person or thing consists. (Incorrect)
    *   Sense 5: `substance%1:10:00::` - what a communication is about (message, content). (Incorrect)
    *   Sense 6: `substance%1:27:00::` - material of a particular kind or constitution. (Possible)
    *   Sense 7: `substance%1:21:00::` - considerable capital (wealth). (Incorrect)

    *   Sense 2: "a particular kind or species of matter with uniform properties" (Example: "shigella is one of the most toxic substances known to man").
    *   Sense 6: "material of a particular kind or constitution" (Example: "the immune response recognizes invading substances").

    *   In pharmaceutical contexts, "active substance" (or active pharmaceutical ingredient - API) refers to the specific chemical compound (matter) that produces the intended pharmacological effect.
    *   Sense 2 describes a "particular kind or species of matter with uniform properties," which fits a chemical compound like pemetrexed perfectly.
    *   Sense 6 describes "material of a particular kind or constitution," which is very similar but often used for more general materials or foreign bodies (like "invading substances").
    *   Comparing the two, Sense 2's focus on "particular kind or species of matter" aligns better with the scientific/chemical definition of a drug substance.

    *   Sense 2: "a particular kind or species of matter with uniform properties" -> Pemetrexed is a specific chemical species.
    *   Sense 6: "material of a particular kind or constitution" -> Also fits, but Sense 2 is more precise for a chemical compound.

    *Wait, let me re-evaluate Sense 2 vs Sense 6.*
    Sense 2: "a particular kind or species of matter with uniform properties"
    Sense 6: "material of a particular kind or constitution"

    In many WordNet-based datasets, "active substance" in a medical context is mapped to the sense of a chemical substance.
    Example for Sense 2: "shigella is one of the most toxic substances known to man" (Shigella is a genus of bacteria, but the sense refers to the matter/species).
    Example for Sense 6: "the immune response recognizes invading substances" (General materials).

    Pemetrexed is a specific chemical compound. Sense 2 ("particular kind or species of matter") is the standard way to describe a chemical substance.

    *Self-Correction:* Let's look at the sense keys provided.
    Sense 2: `substance%1:03:01::`
    Sense 6: `substance%1:27:00::`

    Actually, looking at the definitions again:
    Sense 2: "a particular kind or species of matter with uniform properties"
    Sense 6: "material of a particular kind or constitution"

    In the context of "active substance pemetrexed", it refers to the chemical entity. Sense 2 is the most fitting description for a chemical compound.

    *Double check:*
    Sense 2: particular kind or species of matter.
    Sense 6: material of a particular kind.

    Usually, "substance" in chemistry is defined as a matter with uniform properties.

    Let's check if there's a better fit.
    Sense 4: "the real physical matter of which a person or thing consists" (No).

    Between 2 and 6, 2 is more specific to the "kind/species" of matter, which fits a specific drug name like pemetrexed.

    Sense 2: `substance%1:03:01::`
    Sense 6: `substance%1:27:00::`

    Let's re-read Sense 6: "material of a particular kind or constitution".
    Let's re-read Sense 2: "a particular kind or species of matter with uniform properties".

    Pemetrexed is a chemical substance. Sense 2 is the classic definition of a chemical substance.

    Final check:
    Context: "It contains the active substance pemetrexed."
    Sense 2: "a particular kind or species of matter with uniform properties"
    Sense 6: "material of a particular kind or constitution"

    Sense 2 is slightly more precise for a chemical compound.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta <t>used</t> for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos).

Candidate senses:
1. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
2. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
3. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
4. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
5. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "What is Alimta <t>used</t> for? Alimta is used to treat two types of cancer..."
    *   Meaning: Alimta (a medication) is employed or utilized for the purpose of treating cancer.

    *   Sense 1: `avail oneself to` (practice, apply) - Not applicable.
    *   Sense 2: `seek or achieve an end by using to one's advantage` (e.g., using influential friends) - Not applicable.
    *   Sense 3: `take or consume (regularly or habitually)` (e.g., use drugs) - While Alimta is a drug, the context "used for [treating cancer]" refers to the *purpose* of the drug, not the act of a patient consuming it.
    *   Sense 4: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (utilize, apply, employ) - This fits perfectly. The drug is employed for the purpose of treating cancer.
    *   Sense 5: `use up, consume fully` (expend) - Not applicable.
    *   Sense 6: `habitually do something (use only in the past tense)` (e.g., "used to call") - Not applicable.

    *   The sentence "What is Alimta used for?" asks about the purpose/application of the medication.
    *   Sense 4 specifically mentions "employ for a particular purpose".

    *   Sense 4 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is <t>used</t> to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
2. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
3. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
4. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "What is Alimta used for? Alimta is <t>used</t> to treat two types of cancer..."
    *   Meaning: Alimta (a medicine) is employed or utilized for the purpose of treating cancer.

    *   Sense 1: `take or consume (regularly or habitually)` (e.g., "She uses drugs rarely"). This refers to the *person* using the substance.
    *   Sense 2: `seek or achieve an end by using to one's advantage` (e.g., "She uses her influential friends"). This implies manipulation or strategic advantage.
    *   Sense 3: `habitually do something (use only in the past tense)` (e.g., "She used to call her mother"). This is the auxiliary "used to" for past habits.
    *   Sense 4: `use up, consume fully` (e.g., "expended its time"). This means depletion.
    *   Sense 5: `avail oneself to` (e.g., "apply a principle"). This is more about applying a method or practice.
    *   Sense 6: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (e.g., "use your head!", "we only use Spanish at home").

    *   The sentence "Alimta is used to treat two types of cancer" means Alimta is *employed* or *utilized* for the purpose of treating cancer.
    *   This matches Sense 6: "put into service; make work or employ for a particular purpose".

    *   Sense 1: No, Alimta isn't consuming something.
    *   Sense 2: No, not manipulating for advantage.
    *   Sense 3: No, not a past habit.
    *   Sense 4: No, not consuming fully.
    *   Sense 5: No, not practicing a religion or applying a principle in that specific way.
    *   Sense 6: Yes, employing a medicine for its purpose (treating cancer).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treat
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to <t>treat</t> two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
2. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
3. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke
4. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
7. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
8. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: "treat"
    *   Target surface form: "treat"
    *   Context: "Alimta is used to <t>treat</t> two types of cancer..."
    *   Meaning: In this context, "treat" refers to providing medical care or treatment for a disease (cancer).

    *   Sense 1: engage in negotiations (Incorrect)
    *   Sense 2: provide with choice or abundant food or drink (Incorrect)
    *   Sense 3: regard or consider in a specific way (Incorrect)
    *   Sense 4: interact in a certain way (Incorrect)
    *   Sense 5: provide with a gift or entertainment (Incorrect)
    *   Sense 6: provide treatment for; synonyms: care for; examples: "The doctor treated my broken leg" (Correct)
    *   Sense 7: subject to a process or treatment (industrial/chemical process, e.g., process cheese) (Incorrect)
    *   Sense 8: act on verbally or in some form of artistic expression (Incorrect)

    *   The context is medical ("Alimta is used to treat two types of cancer").
    *   Sense 6 specifically refers to providing medical treatment ("provide treatment for", "The doctor treated my broken leg").


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: types
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two <t>types</t> of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
2. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
3. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
4. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
5. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up
6. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `type`
    *   Target surface form: `types`
    *   Context: "Alimta is used to treat two <t>types</t> of cancer: pleural mesothelioma..."
    *   Candidate senses:
        1.  (biology) taxonomic group...
        2.  printed characters...
        3.  a person of a specified kind...
        4.  a subdivision of a particular kind of thing...
        5.  a small metal block...
        6.  all of the tokens of the same symbol...

    *   The sentence says "two types of cancer".
    *   "Cancer" is a general category of disease.
    *   "Pleural mesothelioma" and "non-small cell lung cancer" are specific kinds or subdivisions of cancer.
    *   Therefore, "types" here means "subdivisions of a particular kind of thing".

    *   Sense 1: Taxonomic group (too specific to biological classification systems).
    *   Sense 2: Printed characters (incorrect).
    *   Sense 3: A person (incorrect).
    *   Sense 4: A subdivision of a particular kind of thing (matches perfectly).
    *   Sense 5: Metal block for printing (incorrect).
    *   Sense 6: Tokens of the same symbol (incorrect).

    *   Sense 4 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of <t>cancer</t>: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
4. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer
5. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 5}
```

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: "Alimta is used to treat two types of <t>cancer</t>: pleural mesothelioma (cancer of the lining of the lungs...)"
    *   Candidate senses:
        1.  Zodiacal constellation.
        2.  Astrological person born in Cancer.
        3.  Fourth sign of the zodiac.
        4.  Genus of crabs (Cancridae).
        5.  Malignant growth/tumor caused by abnormal cell division.

    *   The context discusses "Alimta," a "solution for infusion," "active substance pemetrexed," "treat two types of cancer," "pleural mesothelioma," "anticancer medicine," "chemotherapy," and "non-small cell lung cancer."
    *   This is clearly a medical context referring to the disease.

    *   Sense 1: Constellation (Incorrect)
    *   Sense 2: Astrology person (Incorrect)
    *   Sense 3: Zodiac sign (Incorrect)
    *   Sense 4: Genus of crabs (Incorrect)
    *   Sense 5: Malignant growth or tumor (Correct)

    *   The best sense is index 5.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (<t>cancer</t> of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
4. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: "Alimta is used to treat two types of cancer: pleural mesothelioma (<t>cancer</t> of the lining of the lungs...)"
    *   Candidate senses:
        1.  `cancer%1:26:00::`: malignant growth or tumor caused by abnormal and uncontrolled cell division.
        2.  `cancer%1:18:00::`: (astrology) person born while the sun is in Cancer.
        3.  `cancer%1:15:00::`: fourth sign of the zodiac.
        4.  `cancer%1:17:00::`: zodiacal constellation.
        5.  `cancer%1:05:00::`: type genus of the family Cancridae.

    *   The context discusses "Alimta", a "solution for infusion", "active substance pemetrexed", "treat two types of cancer", "pleural mesothelioma", "lining of the lungs", "anticancer medicine", "chemotherapy", and "non-small cell lung cancer".
    *   This is clearly a medical context referring to a disease.

    *   Sense 1: malignant growth/tumor (Medical) - Matches perfectly.
    *   Sense 2: Astrology (Person) - Incorrect.
    *   Sense 3: Astrology (Sign) - Incorrect.
    *   Sense 4: Astronomy (Constellation) - Incorrect.
    *   Sense 5: Biology (Genus of crabs) - Incorrect.

    *   The best sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: lining
Target surface form: lining
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the <t>lining</t> of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=lining%1:04:00:: | definition=the act of attaching an inside lining (to a garment or curtain etc.)
2. sense_key=lining%1:06:00:: | definition=a protective covering that protects an inside surface | synonyms=liner
3. sense_key=lining%1:06:01:: | definition=a piece of cloth that is used as the inside surface of a garment | synonyms=liner
4. sense_key=lining%1:04:01:: | definition=providing something with a surface of a different material | synonyms=facing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `lining`
    *   Target surface form: `lining`
    *   Context: "...pleural mesothelioma (cancer of the <t>lining</t> of the lungs that is usually caused by exposure to asbestos)."
    *   Candidate senses:
        1.  `lining%1:04:00::`: the act of attaching an inside lining (to a garment or curtain etc.)
        2.  `lining%1:06:00::`: a protective covering that protects an inside surface | synonyms=liner
        3.  `lining%1:06:01::`: a piece of cloth that is used as the inside surface of a garment | synonyms=liner
        4.  `lining%1:04:01::`: providing something with a surface of a different material | synonyms=facing

    *   The context refers to the "lining of the lungs" in the context of pleural mesothelioma.
    *   In anatomy, a lining is a membrane or layer of tissue that covers an internal surface.
    *   Looking at the candidate senses:
        *   Sense 1: Act of attaching (process) - Incorrect.
        *   Sense 2: A protective covering that protects an inside surface - This fits the anatomical description of a lining (like the pleura).
        *   Sense 3: A piece of cloth (garment) - Incorrect.
        *   Sense 4: Providing something with a surface (process) - Incorrect.

    *   Sense 2 is the most general definition of a "lining" as a protective covering for an inside surface, which encompasses biological membranes.

    *   Sense 2: "a protective covering that protects an inside surface"
    *   Context: "lining of the lungs"
    *   This is a perfect match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cause
Target surface form: caused
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually <t>caused</t> by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cause%2:32:00:: | definition=cause to do; cause to act in a specified manner | synonyms=induce, stimulate, have, get, make | examples=The ads induced me to buy a VCR; My children finally got me to buy a computer
2. sense_key=cause%2:36:00:: | definition=give rise to; cause to happen or occur, not always intentionally | synonyms=do, make | examples=cause a commotion; make a stir

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `cause`
    *   Target surface form: `caused`
    *   Context: "...pleural mesothelioma (cancer of the lining of the lungs that is usually <t>caused</t> by exposure to asbestos)."
    *   Candidate senses:
        1.  `cause%2:32:00::`: cause to do; cause to act in a specified manner (induce, stimulate). Example: "The ads induced me to buy a VCR."
        2.  `cause%2:36:00::`: give rise to; cause to happen or occur, not always intentionally. Example: "cause a commotion."

    *   The sentence says: "cancer of the lining of the lungs that is usually caused by exposure to asbestos."
    *   Here, "caused" means that exposure to asbestos *gives rise to* or *makes happen* the cancer.
    *   It is not about inducing someone to act in a certain way (Sense 1).
    *   It is about an event or condition (cancer) being brought about by a factor (asbestos).

    *   Sense 1: "cause to do; cause to act in a specified manner" (Focus on agency/action).
    *   Sense 2: "give rise to; cause to happen or occur" (Focus on causation/occurrence).

    *   The context "caused by exposure to asbestos" fits perfectly with "give rise to; cause to happen or occur".

    *   Sense index: 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is <t>used</t> together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
2. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
5. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
6. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "Alimta is <t>used</t> together with cisplatin (another anticancer medicine)..."
    *   General context: A medical description of a drug (Alimta) and how it is administered/prescribed for treating cancer.

    *   Sense 1: `avail oneself to` (practice, apply) - e.g., practice a religion. (Not applicable)
    *   Sense 2: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (utilize, utilise, apply, employ) - e.g., use your head!, we only use Spanish at home. (Fits well: the drug is employed for a medical purpose).
    *   Sense 3: `use up, consume fully` (expend) - e.g., expended its time. (Not applicable)
    *   Sense 4: `take or consume (regularly or habitually)` (habituate) - e.g., uses drugs rarely. (While it's a drug, "used together with" refers to the medical application/administration, not a habit).
    *   Sense 5: `habitually do something (use only in the past tense)` - e.g., used to call her mother. (Not applicable)
    *   Sense 6: `seek or achieve an end by using to one's advantage` - e.g., uses her influential friends. (Not applicable)

    *   The sentence "Alimta is used together with cisplatin" means that Alimta is employed or utilized as a treatment method.
    *   This aligns perfectly with Sense 2: "put into service; make work or employ for a particular purpose".

    *   Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer <t>medicine</t>) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
2. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
3. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicine`
    *   Context: "Alimta is used together with cisplatin (another anticancer <t>medicine</t>)..."
    *   Candidate senses:
        1.  `medicine%1:06:00::`: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).
        2.  `medicine%1:04:00::`: the learned profession... (practice of medicine).
        3.  `medicine%1:09:00::`: the branches of medical science... (medical specialty).
        4.  `medicine%1:04:02::`: punishment for one's actions (take your medicine).

    *   The sentence says "cisplatin (another anticancer medicine)".
    *   Cisplatin is a chemical substance used to treat cancer.
    *   This fits the definition of a medication or medicinal drug.

    *   Sense 1: Medication/drug. (Matches perfectly)
    *   Sense 2: Profession/study. (Does not match)
    *   Sense 3: Medical science/specialty. (Does not match)
    *   Sense 4: Punishment. (Does not match)

    *   The best sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the <t>cancer</t> is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
4. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
5. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: A medical description of the drug Alimta, used to treat "two types of cancer: pleural mesothelioma... when the <t>cancer</t> is unresectable... and malignant... chemotherapy (medicines for cancer)..."
    *   Candidate senses:
        1.  `cancer%1:05:00::`: genus of the family Cancridae (biological genus).
        2.  `cancer%1:18:00::`: person born under the sign of Cancer (astrology).
        3.  `cancer%1:15:00::`: fourth sign of the zodiac (astrology).
        4.  `cancer%1:17:00::`: zodiacal constellation (astronomy).
        5.  `cancer%1:26:00::`: malignant growth or tumor caused by abnormal cell division (medical).

    *   The context discusses "Alimta", "infusion", "pemetrexed", "pleural mesothelioma", "unresectable", "malignant", "chemotherapy", and "non-small cell lung cancer".
    *   All these terms are medical and relate to the disease known as cancer.

    *   Sense 1: Biological genus (Incorrect).
    *   Sense 2: Person born in June/July (Incorrect).
    *   Sense 3: Zodiac sign (Incorrect).
    *   Sense 4: Constellation (Incorrect).
    *   Sense 5: Malignant growth/tumor (Correct).

    *   The target word "cancer" in the context refers to the disease.
    *   Sense 5 matches this definition perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: remove
Target surface form: removed
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be <t>removed</t> by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=remove%2:30:00:: | definition=remove something concrete, as by lifting, pushing, or taking off, or remove something abstract | synonyms=take, take away, withdraw | examples=remove a threat; remove a wrapper
2. sense_key=remove%2:38:00:: | definition=shift the position or location of, as for business, legal, educational, or military purposes | synonyms=transfer | examples=He removed his children to the countryside; Remove the troops to the forest surrounding the city
3. sense_key=remove%2:41:01:: | definition=kill intentionally and with premeditation | synonyms=murder, slay, hit, dispatch, bump off, off | examples=The mafia boss ordered his enemies murdered
4. sense_key=remove%2:30:01:: | definition=go away or leave | synonyms=absent | examples=He absented himself
5. sense_key=remove%2:41:00:: | definition=remove from a position or an office
6. sense_key=remove%2:41:02:: | definition=cause to leave | synonyms=take out, move out | examples=The teacher took the children out of the classroom
7. sense_key=remove%2:40:00:: | definition=dispose of | synonyms=get rid of | examples=Get rid of these old shoes!; The company got rid of all the dead wood
8. sense_key=remove%2:30:02:: | definition=get rid of something abstract | synonyms=take away | examples=The death of her mother removed the last obstacle to their marriage; God takes away your sins

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `remove`
    *   Target surface form: `removed`
    *   Context: "...when the cancer is unresectable (cannot be <t>removed</t> by surgery alone)..."
    *   Meaning: In a medical context, "removing" cancer via surgery means physically taking the tumor/cancerous tissue out of the body.

    *   Sense 1: `remove something concrete, as by lifting, pushing, or taking off, or remove something abstract` (Synonyms: take, take away, withdraw; Examples: remove a threat; remove a wrapper).
    *   Sense 2: `shift the position or location of, as for business, legal, educational, or military purposes` (Synonyms: transfer).
    *   Sense 3: `kill intentionally and with premeditation` (Synonyms: murder, slay).
    *   Sense 4: `go away or leave` (Synonyms: absent).
    *   Sense 5: `remove from a position or an office`.
    *   Sense 6: `cause to leave` (Synonyms: take out, move out).
    *   Sense 7: `dispose of` (Synonyms: get rid of).
    *   Sense 8: `get rid of something abstract` (Synonyms: take away).

    *   The context is surgical removal of a tumor. This is a physical action of taking something concrete (the tumor) out of the body.
    *   Sense 1 covers removing something concrete (like a wrapper) or abstract.
    *   Sense 7 ("dispose of") is close, but "remove by surgery" is more about the physical act of extraction (taking it out) than just "getting rid of" it in a general sense.
    *   Sense 6 ("cause to leave") is usually used for people (e.g., children from a classroom).
    *   Sense 1's definition "remove something concrete, as by lifting, pushing, or taking off" fits the physical extraction of a tumor best.

    *   Sense 1: "remove something concrete... as by... taking off" -> Fits surgical removal.
    *   Sense 7: "dispose of" -> Too general.
    *   Sense 8: "get rid of something abstract" -> Not abstract.

    *   The most accurate sense for surgical removal of a physical object (cancer) is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: surgery
Target surface form: surgery
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by <t>surgery</t> alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=surgery%1:09:00:: | definition=the branch of medical science that treats disease or injury by operative procedures | examples=he is professor of surgery at the Harvard Medical School
2. sense_key=surgery%1:06:01:: | definition=a room where a doctor or dentist can be consulted | examples=he read the warning in the doctor's surgery
3. sense_key=surgery%1:04:01:: | definition=a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body | synonyms=operation, surgical operation, surgical procedure, surgical process | examples=they will schedule the operation as soon as an operating room is available; he died while undergoing surgery
4. sense_key=surgery%1:06:00:: | definition=a room in a hospital equipped for the performance of surgical operations | synonyms=operating room, OR, operating theater, operating theatre | examples=great care is taken to keep the operating rooms aseptic

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `surgery`
    *   Target surface form: `surgery`
    *   Context: "...when the cancer is unresectable (cannot be removed by <t>surgery</t> alone)..."
    *   Candidate senses:
        1.  `surgery%1:09:00::`: branch of medical science (academic/field).
        2.  `surgery%1:06:01::`: doctor's office/consultation room.
        3.  `surgery%1:04:01::`: medical procedure involving an incision (operation).
        4.  `surgery%1:06:00::`: operating room (physical space).

    *   The phrase is "cannot be removed by surgery alone".
    *   "Removed by surgery" refers to the act of surgically removing a tumor (an operation).
    *   It does not refer to the field of study (sense 1), the doctor's office (sense 2), or the physical room (sense 4).
    *   It refers to the medical procedure/operation itself.

    *   Sense 3: "a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body". Synonyms: operation, surgical operation.
    *   This fits perfectly.

    *   Sense 1: Field of science. (Incorrect)
    *   Sense 2: Consultation room. (Incorrect)
    *   Sense 4: Operating room. (Incorrect)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: alone
Target surface form: alone
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=alone%5:00:00:incomparable:00 | definition=radically distinctive and without equal | synonyms=unique, unequaled, unequalled, unparalleled | examples=he is alone in the field of microbiology; this theory is altogether alone in its penetration of the problem
2. sense_key=alone%5:00:00:unsocial:00 | definition=isolated from others | examples=could be alone in a crowded room; was alone with her thoughts
3. sense_key=alone%5:00:00:exclusive:00 | definition=exclusive of anyone or anything else | synonyms=only | examples=she alone believed him; cannot live by bread alone
4. sense_key=alone%5:00:00:unaccompanied:00 | definition=lacking companions or companionship | synonyms=lone, lonely, solitary | examples=he was alone when we met him; she is alone much of the time

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "alone"
    *   Target surface form: "alone"
    *   Context: "...when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant..."
    *   Candidate senses:
        1.  `incomparable`: radically distinctive and without equal (e.g., "alone in the field of microbiology").
        2.  `unsocial`: isolated from others (e.g., "alone in a crowded room").
        3.  `exclusive`: exclusive of anyone or anything else; synonyms: "only" (e.g., "cannot live by bread alone").
        4.  `unaccompanied`: lacking companions or companionship (e.g., "he was alone when we met him").

    *   The phrase is "cannot be removed by surgery alone".
    *   This means surgery *by itself* or *only* surgery is not sufficient to remove the cancer.
    *   Substituting "only" (the synonym for sense 3): "cannot be removed by surgery only". This fits perfectly.

    *   Sense 1 (incomparable): Does not fit. Surgery is not "radically distinctive" here.
    *   Sense 2 (unsocial): Does not fit. Surgery is not "isolated from others" in a social sense.
    *   Sense 3 (exclusive): Fits. "Exclusive of anyone or anything else" / "only".
    *   Sense 4 (unaccompanied): Does not fit. Surgery is not "lacking companions" in a social sense.

    *   The best fit is sense 3.