[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
Like all genes, tumor-suppressor genes are inherited in two copies, one from each parent. Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye <t>cancer</t> that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby.

Candidate senses:
1. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer
2. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
3. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: "...retinoblastoma, an eye <t>cancer</t> that occurs about once every 20,000 births."
    *   Surrounding context mentions: "tumor-suppressor genes", "cell growth", "malignant growth or tumor", "retinoblastoma", "rare tumor".

    *   Sense 1: `cancer%1:05:00::` - type genus of the family Cancridae (Crabs).
    *   Sense 2: `cancer%1:17:00::` - a small zodiacal constellation.
    *   Sense 3: `cancer%1:18:00::` - (astrology) a person born while the sun is in Cancer.
    *   Sense 4: `cancer%1:15:00::` - the fourth sign of the zodiac.
    *   Sense 5: `cancer%1:26:00::` - any malignant growth or tumor caused by abnormal and uncontrolled cell division.

    *   The context explicitly discusses "tumor-suppressor genes", "cell growth", "retinoblastoma", and "rare tumor".
    *   This aligns perfectly with Sense 5: "any malignant growth or tumor caused by abnormal and uncontrolled cell division".

    *   Sense 5 is the correct one.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: occur
Target surface form: occurs
Context:
Like all genes, tumor-suppressor genes are inherited in two copies, one from each parent. Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that <t>occurs</t> about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby.

Candidate senses:
1. sense_key=occur%2:42:03:: | definition=to be found to exist | examples=sexism occurs in many workplaces; precious stones occur in a large area in Brazil
2. sense_key=occur%2:30:00:: | definition=come to pass | synonyms=happen, hap, go on, pass off, pass, fall out | examples=What is happening?; The meeting took place off without an incidence
3. sense_key=occur%2:31:00:: | definition=come to one's mind; suggest itself | synonyms=come | examples=It occurred to me that we should hire another secretary; A great idea then came to her

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

finish_reason: stop

content:
```json
{"sense_index": 1}
```

role: assistant

reasoning_content:
*   Target lemma: `occur`
    *   Target surface form: `occurs`
    *   Context: "...retinoblastoma, an eye cancer that <t>occurs</t> about once every 20,000 births."

    *   Sense 1: `occur%2:42:03::` | definition: "to be found to exist" | examples: "sexism occurs in many workplaces; precious stones occur in a large area in Brazil"
    *   Sense 2: `occur%2:30:00::` | definition: "come to pass" | synonyms: "happen, hap, go on, pass off, pass, fall out" | examples: "What is happening?; The meeting took place off without an incidence"
    *   Sense 3: `occur%2:31:00::` | definition: "come to one's mind; suggest itself" | synonyms: "come" | examples: "It occurred to me that we should hire another secretary; A great idea then came to her"

    *   The sentence describes the frequency of a medical condition (retinoblastoma) in a population ("about once every 20,000 births").
    *   Does it mean "come to one's mind" (Sense 3)? No.
    *   Does it mean "come to pass" (Sense 2 - happen)? In a general sense, yes, a disease "happens" to people.
    *   Does it mean "to be found to exist" (Sense 1)? In a medical/scientific context, when describing the prevalence or incidence of a disease or a trait in a population, "occur" often means "to be found" or "to exist".

    *   Sense 1: "to be found to exist" (e.g., "precious stones occur in a large area in Brazil"). This fits the pattern of describing the distribution or prevalence of something.
    *   Sense 2: "come to pass" (e.g., "The meeting took place"). This usually refers to an event.

    *   "An eye cancer that occurs about once every 20,000 births."
    *   This is describing the *incidence* or *prevalence* of the cancer.
    *   Comparing "to be found to exist" (Sense 1) vs "come to pass/happen" (Sense 2).
    *   If we say "The accident occurred at 5 PM," that's Sense 2.
    *   If we say "This species occurs only in Madagascar," that's Sense 1.
    *   "Retinoblastoma occurs about once every 20,000 births" is more like "This condition is found in about 1 in 20,000 births."

    *   Sense 1: "to be found to exist" (distribution/prevalence).
    *   Sense 2: "come to pass" (event/happening).
    *   Medical incidence is typically treated as a distribution/existence in a population.

    *   Sense 1: "sexism occurs in many workplaces" (prevalence).
    *   Sense 2: "What is happening?" (event).
    *   "Retinoblastoma occurs about once every 20,000 births" is very similar to "sexism occurs in many workplaces." It's about how often it is found.

    *   Sense 1 is the best fit.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: about
Target surface form: about
Context:
Like all genes, tumor-suppressor genes are inherited in two copies, one from each parent. Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs <t>about</t> once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby.

Candidate senses:
1. sense_key=about%4:02:04:: | definition=used of movement to or among many different places or in no particular direction | synonyms=around | examples=wandering about with no place to go; people were rushing about
2. sense_key=about%4:02:06:: | definition=all around or on all sides | synonyms=around | examples=dirty clothes lying around (or about); let's look about for help
3. sense_key=about%4:02:02:: | definition=in or to a reversed position or direction | synonyms=around | examples=about face; suddenly she turned around
4. sense_key=about%4:02:05:: | definition=(of actions or states) slightly short of or not quite accomplished; all but | synonyms=almost, most, nearly, near, nigh, virtually | examples=the job is (just) about done; the baby was almost asleep when the alarm sounded
5. sense_key=about%4:02:03:: | definition=in rotation or succession | examples=turn about is fair play
6. sense_key=about%4:02:00:: | definition=(of quantities) imprecise but fairly close to correct | synonyms=approximately, close to, just about, some, roughly, more or less | examples=lasted approximately an hour; in just about a minute
7. sense_key=about%4:02:01:: | definition=in the area or vicinity | synonyms=around | examples=a few spectators standing about; hanging around

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: "about"
    *   Target surface form: "about"
    *   Context: "...an eye cancer that occurs <t>about</t> once every 20,000 births."

    *   Sense 1: movement to/among many places (around).
    *   Sense 2: all around or on all sides (around).
    *   Sense 3: reversed position or direction (around).
    *   Sense 4: slightly short of or not quite accomplished (almost).
    *   Sense 5: in rotation or succession.
    *   Sense 6: (of quantities) imprecise but fairly close to correct (approximately).
    *   Sense 7: in the area or vicinity (around).

    *   The phrase is "about once every 20,000 births."
    *   "Once every 20,000 births" is a quantity/frequency.
    *   "About" here means "approximately" or "roughly."

    *   Sense 6: "(of quantities) imprecise but fairly close to correct | synonyms=approximately, close to, just about, some, roughly, more or less | examples=lasted approximately an hour; in just about a minute"
    *   This matches perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: once
Target surface form: once
Context:
Like all genes, tumor-suppressor genes are inherited in two copies, one from each parent. Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about <t>once</t> every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby.

Candidate senses:
1. sense_key=once%4:02:00:: | definition=on one occasion | synonyms=one time, in one case | examples=once I ran into her
2. sense_key=once%4:02:02:: | definition=as soon as | examples=once we are home, we can rest
3. sense_key=once%4:02:01:: | definition=at a previous time | synonyms=formerly, at one time, erstwhile, erst | examples=at one time he loved her; her erstwhile writing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "once"
    *   Target surface form: "once"
    *   Context: "...an eye cancer that occurs about <t>once</t> every 20,000 births."

    *   Sense 1: "on one occasion" (synonyms: one time, in one case). Example: "once I ran into her".
    *   Sense 2: "as soon as". Example: "once we are home, we can rest".
    *   Sense 3: "at a previous time" (synonyms: formerly, at one time). Example: "at one time he loved her".

    *   The phrase is "once every 20,000 births".
    *   This describes frequency or a rate of occurrence.
    *   "Once" here means "one time" in a specific interval (every 20,000 births).
    *   Comparing this to the senses:
        *   Sense 1 ("on one occasion", "one time") fits the idea of a single occurrence within a set.
        *   Sense 2 ("as soon as") is a temporal conjunction. Not applicable.
        *   Sense 3 ("at a previous time") refers to the past. Not applicable.

    *   Sense 1 is the only one that fits the meaning of "one time" or "on one occasion" (even though it's used here to describe a rate/frequency).

    *   Sense 1: "on one occasion" / "one time".
    *   Context: "once every 20,000 births" -> "one time every 20,000 births".
    *   This is the correct sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: birth
Target surface form: births
Context:
Like all genes, tumor-suppressor genes are inherited in two copies, one from each parent. Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 <t>births</t>. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby.

Candidate senses:
1. sense_key=birth%1:22:00:: | definition=the process of giving birth | synonyms=parturition, giving birth, birthing
2. sense_key=birth%1:24:00:: | definition=the kinship relation of an offspring to the parents | synonyms=parentage
3. sense_key=birth%1:18:00:: | definition=a baby born; an offspring | examples=the overall rate of incidence of Down's syndrome is one in every 800 births
4. sense_key=birth%1:28:00:: | definition=the time when something begins (especially life) | examples=they divorced after the birth of the child; his election signaled the birth of a new age
5. sense_key=birth%1:11:00:: | definition=the event of being born | synonyms=nativity, nascency, nascence | examples=they celebrated the birth of their first child

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `birth`
    *   Target surface form: `births`
    *   Context: "...retinoblastoma, an eye cancer that occurs about once every 20,000 <t>births</t>."

    *   Sense 1: `the process of giving birth` (parturition) - Not about the process of delivery.
    *   Sense 2: `the kinship relation of an offspring to the parents` (parentage) - Not about kinship.
    *   Sense 3: `a baby born; an offspring` (Example: "the overall rate of incidence of Down's syndrome is one in every 800 births") - This matches the context perfectly. The phrase "once every 20,000 births" refers to the number of babies born.
    *   Sense 4: `the time when something begins (especially life)` - Not about the specific time/start.
    *   Sense 5: `the event of being born` (nativity) - While similar to Sense 3, Sense 3 specifically provides an example of incidence rates ("one in every 800 births"), which is exactly how the target word is used in the context ("once every 20,000 births").

    *   Context: "once every 20,000 births"
    *   Sense 3 Example: "one in every 800 births"
    *   The usage is identical. Sense 3 refers to the offspring/babies born.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: know
Target surface form: knew
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, <t>knew</t> he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=know%2:31:14:: | definition=perceive as familiar | examples=I know this voice!
2. sense_key=know%2:35:00:: | definition=have sexual intercourse with | synonyms=sleep together, roll in the hay, love, make out, make love, sleep with | examples=This student sleeps with everyone in her dorm; Adam knew Eve
3. sense_key=know%2:31:03:: | definition=know how to do or perform something | examples=She knows how to knit; Does your husband know how to cook?
4. sense_key=know%2:31:06:: | definition=accept (someone) to be what is claimed or accept his power and authority | synonyms=acknowledge, recognize, recognise | examples=The Crown Prince was acknowledged as the true heir to the throne; We do not recognize your gods
5. sense_key=know%2:31:04:: | definition=have firsthand knowledge of states, situations, emotions, or sensations | synonyms=experience, live | examples=I know the feeling!; have you ever known hunger?
6. sense_key=know%2:31:02:: | definition=be aware of the truth of something; have a belief or faith in something; regard as true beyond any doubt | examples=I know that I left the key on the table; Galileo knew that the earth moves around the sun
7. sense_key=know%2:31:00:: | definition=be familiar or acquainted with a person or an object | examples=She doesn't know this composer; Do you know my sister?
8. sense_key=know%2:31:01:: | definition=be cognizant or aware of a fact or a specific piece of information; possess knowledge or information about | synonyms=cognize, cognise | examples=I know that the President lied to the people; I want to know who is winning the game!
9. sense_key=know%2:31:11:: | definition=know the nature or character of | examples=we all knew her as a big show-off
10. sense_key=know%2:31:15:: | definition=have fixed in the mind | examples=I know Latin; This student knows her irregular verbs
11. sense_key=know%2:31:12:: | definition=be able to distinguish, recognize as being different | examples=The child knows right from wrong

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 8}
```

content:
```json
{"sense_index": 8}
```

reasoning_content:
*   Target lemma: `know`
    *   Target surface form: `knew`
    *   Context: "Mr. Quinlan, 30 years old, <t>knew</t> he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old..."
    *   Meaning: Mr. Quinlan was aware of the fact that he carried a damaged gene.

    *   1: perceive as familiar (e.g., "I know this voice!") - No.
    *   2: have sexual intercourse with - No.
    *   3: know how to do or perform something - No.
    *   4: accept (someone) to be what is claimed - No.
    *   5: have firsthand knowledge of states, situations, emotions, or sensations (experience) - No.
    *   6: be aware of the truth of something; have a belief or faith in something; regard as true beyond any doubt - Possible.
    *   7: be familiar or acquainted with a person or an object - No.
    *   8: be cognizant or aware of a fact or a specific piece of information; possess knowledge or information about - Very likely.
    *   9: know the nature or character of - No.
    *   10: have fixed in the mind (e.g., "I know Latin") - No.
    *   11: be able to distinguish, recognize as being different - No.

    *   Sense 6: "be aware of the truth of something; have a belief or faith in something; regard as true beyond any doubt"
    *   Sense 8: "be cognizant or aware of a fact or a specific piece of information; possess knowledge or information about"

    *   The sentence says "Mr. Quinlan... knew he carried a damaged gene". This is a specific piece of medical information/fact.
    *   Sense 8 specifically mentions "be cognizant or aware of a fact or a specific piece of information".
    *   Sense 6 is more about belief, faith, or truth beyond doubt.
    *   In this context, knowing he carried a gene is possessing a specific piece of information (likely confirmed by his medical history/family history).

    *   Sense 8 fits best as it describes being aware of a specific fact.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: carry
Target surface form: carried
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he <t>carried</t> a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=carry%2:29:00:: | definition=be pregnant with | synonyms=have a bun in the oven, bear, gestate, expect | examples=She is bearing his child; The are expecting another child in January
2. sense_key=carry%2:41:02:: | definition=win approval or support for | synonyms=persuade, sway | examples=Carry all before one; His speech did not sway the voters
3. sense_key=carry%2:33:01:: | definition=win in an election | examples=The senator carried his home state
4. sense_key=carry%2:40:00:: | definition=have on hand | synonyms=stock, stockpile | examples=Do you carry kerosene heaters?
5. sense_key=carry%2:33:02:: | definition=secure the passage or adoption (of bills and motions) | examples=The motion carried easily
6. sense_key=carry%2:42:03:: | definition=contain or hold; have within | synonyms=hold, bear, contain | examples=The jar carries wine; The canteen holds fresh water
7. sense_key=carry%2:41:00:: | definition=extend to a certain degree | examples=carry too far; She carries her ideas to the extreme
8. sense_key=carry%2:40:10:: | definition=have on the surface or on the skin | examples=carry scars
9. sense_key=carry%2:34:00:: | definition=drink alcohol without showing ill effects | synonyms=hold | examples=He can hold his liquor; he had drunk more than he could carry
10. sense_key=carry%2:40:04:: | definition=capture after a fight | examples=The troops carried the town after a brief fight
11. sense_key=carry%2:36:00:: | definition=include as the content; broadcast or publicize | synonyms=run | examples=We ran the ad three times; This paper carries a restaurant review
12. sense_key=carry%2:33:12:: | definition=be successful in | examples=She lost the game but carried the match
13. sense_key=carry%2:35:09:: | definition=bear or be able to bear the weight, pressure,or responsibility of | examples=His efforts carried the entire project; How many credits is this student carrying?
14. sense_key=carry%2:42:08:: | definition=be equipped with (a mast or sail) | examples=This boat can only carry a small sail
15. sense_key=carry%2:40:13:: | definition=transfer (entries) from one account book to another | synonyms=post
16. sense_key=carry%2:41:12:: | definition=take further or advance | examples=carry a cause
17. sense_key=carry%2:41:01:: | definition=behave in a certain manner | synonyms=behave, acquit, bear, deport, conduct, comport | examples=She carried herself well; he bore himself with dignity
18. sense_key=carry%2:38:03:: | definition=transmit or serve as the medium for transmission | synonyms=impart, conduct, transmit, convey, channel | examples=Sound carries well over water; The airwaves carry the sound
19. sense_key=carry%2:35:08:: | definition=propel, | synonyms=dribble | examples=Carry the ball; dribble the ball
20. sense_key=carry%2:42:14:: | definition=keep up with financial support | examples=The Federal Government carried the province for many years
21. sense_key=carry%2:32:00:: | definition=sing or play against other voices or parts | examples=He cannot carry a tune
22. sense_key=carry%2:38:07:: | definition=pursue a line of scent or be a bearer | examples=the dog was taught to fetch and carry
23. sense_key=carry%2:42:12:: | definition=have or possess something abstract | examples=I carry her image in my mind's eye; I will carry the secret to my grave
24. sense_key=carry%2:41:06:: | definition=compensate for a weaker partner or member by one's own performance | examples=I resent having to carry her all the time
25. sense_key=carry%2:35:12:: | definition=propel or give impetus to | examples=The sudden gust of air propelled the ball to the other side of the fence
26. sense_key=carry%2:30:05:: | definition=continue or extend | synonyms=extend | examples=The civil war carried into the neighboring province; The disease extended into the remote mountain provinces
27. sense_key=carry%2:32:07:: | definition=pass on a communication | examples=The news was carried to every village in the province
28. sense_key=carry%2:31:12:: | definition=include, as on a list | examples=How many people are carried on the payroll?
29. sense_key=carry%2:42:02:: | definition=be necessarily associated with or result in or involve | examples=This crime carries a penalty of five years in prison
30. sense_key=carry%2:42:15:: | definition=be conveyed over a certain distance | examples=Her voice carries very well in this big opera house
31. sense_key=carry%2:33:03:: | definition=cover a certain distance or advance beyond | examples=The drive carried to the green
32. sense_key=carry%2:34:01:: | definition=be able to feed | examples=This land will carry ten cows to the acre
33. sense_key=carry%2:35:01:: | definition=support or hold in a certain manner | synonyms=hold, bear | examples=She holds her head high; He carried himself upright
34. sense_key=carry%2:33:04:: | definition=have a certain range | examples=This rifle carries for 3,000 feet
35. sense_key=carry%2:36:08:: | definition=bear (a crop) | examples=this land does not carry olives
36. sense_key=carry%2:42:13:: | definition=have as an inherent or characteristic feature or have as a consequence | examples=This new washer carries a two year guarantee; The loan carries a high interest rate
37. sense_key=carry%2:42:01:: | definition=have with oneself; have on one's person | synonyms=pack, take | examples=She always takes an umbrella; I always carry money
38. sense_key=carry%2:35:02:: | definition=move while supporting, either in a vehicle or in one's hands or on one's body | synonyms=transport | examples=You must carry your camping gear; carry the suitcases to the car
39. sense_key=carry%2:32:02:: | definition=serve as a means for expressing something | synonyms=convey, express | examples=The painting of Mary carries motherly love; His voice carried a lot of anger
40. sense_key=carry%2:38:10:: | definition=transfer (a number, cipher, or remainder) to the next column or unit's place before or after, in addition or multiplication | examples=put down 5 and carry 2

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `carry`
    *   Target surface form: `carried`
    *   Context: "Mr. Quinlan, 30 years old, knew he <t>carried</t> a damaged gene..."
    *   Meaning: Mr. Quinlan possesses a damaged gene in his genetic makeup.

    *   1: be pregnant with (No)
    *   2: win approval or support for (No)
    *   3: win in an election (No)
    *   4: have on hand (stock) (No)
    *   5: secure passage of bills (No)
    *   6: contain or hold; have within (Possible: "contain or hold; have within")
    *   7: extend to a certain degree (No)
    *   8: have on the surface or on the skin (No - genes are internal)
    *   9: drink alcohol without showing ill effects (No)
    *   10: capture after a fight (No)
    *   11: include as content; broadcast (No)
    *   12: be successful in (No)
    *   13: bear weight/pressure/responsibility (No)
    *   14: be equipped with (mast/sail) (No)
    *   15: transfer entries (No)
    *   16: take further or advance (No)
    *   17: behave in a certain manner (No)
    *   18: transmit or serve as medium (No - this is about the *act* of transmission, not possessing the gene)
    *   19: propel (dribble) (No)
    *   20: keep up with financial support (No)
    *   21: sing or play against other voices (No)
    *   22: pursue a line of scent (No)
    *   23: have or possess something abstract (No - a gene is biological, though "damaged gene" could be seen as a trait, it's more physical/biological than "image in my mind's eye")
    *   24: compensate for a weaker partner (No)
    *   25: propel or give impetus to (No)
    *   26: continue or extend (No)
    *   27: pass on a communication (No)
    *   28: include, as on a list (No)
    *   29: be necessarily associated with or result in (No)
    *   30: be conveyed over a certain distance (No)
    *   31: cover a certain distance (No)
    *   32: be able to feed (No)
    *   33: support or hold in a certain manner (No)
    *   34: have a certain range (No)
    *   35: bear (a crop) (No)
    *   36: have as an inherent or characteristic feature (Possible: "have as an inherent or characteristic feature or have as a consequence")
    *   37: have with oneself; have on one's person (No - genes aren't carried like an umbrella)
    *   38: move while supporting (No)
    *   39: serve as a means for expressing something (No)
    *   40: transfer a number (No)

    *   Sense 6: "contain or hold; have within" (Synonyms: hold, bear, contain). Example: "The jar carries wine".
    *   Sense 36: "have as an inherent or characteristic feature or have as a consequence". Example: "This new washer carries a two year guarantee".
    *   Sense 23: "have or possess something abstract". Example: "I carry her image in my mind's eye".

    *   Is a gene "contained or held within" (Sense 6)? Yes.
    *   Is a gene an "inherent or characteristic feature" (Sense 36)? Yes.
    *   Is a gene "something abstract" (Sense 23)? No.

    Let's look closer at Sense 6 vs Sense 36.
    Sense 6: "contain or hold; have within". This is often used for physical containers (jar, canteen).
    Sense 36: "have as an inherent or characteristic feature". This is often used for guarantees or interest rates.

    Wait, let's re-examine Sense 6. "contain or hold; have within". A person "contains" or "has within" their DNA a specific gene.

    Let's look for other possibilities. Is there a sense for "carrying a trait/gene"?
    In genetics, "carrying a gene" means possessing it.

    Let's re-read Sense 6: "contain or hold; have within".
    Let's re-read Sense 36: "have as an inherent or characteristic feature".

    Actually, let's look at Sense 6 again. "The jar carries wine". This is very literal.
    Sense 36: "This new washer carries a two year guarantee". This is more about a property or feature.

    Is there any other sense?
    Sense 8: "have on the surface or on the skin" (No).
    Sense 18: "transmit or serve as the medium for transmission" (No, that's the *action* of the gene being passed, not the state of having it).

    Let's compare "carry a gene" with the provided senses.
    "He carried a damaged gene."
    This means he *possesses* the gene.

    Looking at Sense 6: "contain or hold; have within".
    Looking at Sense 36: "have as an inherent or characteristic feature".

    If we look at how "carry" is used in medical/genetic contexts, it often means to be a carrier (possessing the gene).

    Let's check Sense 6 again. "contain or hold; have within".
    Let's check Sense 36 again. "have as an inherent or characteristic feature".

    A gene is an inherent feature of a person's biological makeup.

    Wait, let's look at Sense 6's synonyms: "hold, bear, contain".
    "Bear" is often used for genes (e.g., "bear a mutation").

    Let's look at Sense 36's examples: "guarantee", "interest rate". These are contractual or financial features.

    Let's look at Sense 6's examples: "The jar carries wine". This is a physical container.

    Is there any other sense?
    Sense 23: "have or possess something abstract". A gene isn't really abstract.

    Let's reconsider Sense 6. "contain or hold; have within". A person's body contains their genes.

    Let's search for "carry a gene" in WordNet-like contexts. Usually, "carry" in the sense of "carrying a disease" or "carrying a gene" is mapped to "possess" or "contain".

    Let's re-evaluate Sense 6: "contain or hold; have within".
    Let's re-evaluate Sense 36: "have as an inherent or characteristic feature".

    If I have to choose between "contain/hold within" and "inherent feature", "contain/hold within" (Sense 6) feels slightly more aligned with the biological presence of a gene, although "inherent feature" (Sense 36) also fits. However, Sense 36's examples (guarantee, interest rate) are very different from biological traits.

    Let's look at Sense 6 again. "The jar carries wine".
    Wait, let's look at Sense 8: "have on the surface or on the skin". (No).

    What about Sense 18? "transmit or serve as the medium for transmission".
    "Mr. Quinlan... knew he carried a damaged gene".
    In genetics, a "carrier" is someone who *can* transmit the gene to their offspring.
    Sense 18: "transmit or serve as the medium for transmission".
    Example: "Sound carries well over water". (This is about the medium of the sound wave).
    Example: "The airwaves carry the sound".

    Wait, "carry a gene" often means "to be a carrier of". A carrier is someone who possesses the gene and can pass it on.

    Let's look at Sense 6 again. "contain or hold; have within".
    If you "carry" a gene, you "have it within" you.

    Let's double-check Sense 36 again. "have as an inherent or characteristic feature".
    A damaged gene is an inherent feature of his DNA.

    Let's think about the most common mapping for "carry a gene".
    In many WSD datasets, "carry a gene" or "carry a disease" is mapped to "possess" or "contain".

    Let's look at the options one more time.
    Sense 6: contain or hold; have within.
    Sense 36: have as an inherent or characteristic feature.

    Comparing "The jar carries wine" (6) and "The loan carries a high interest rate" (36).
    A gene is more like a physical (though microscopic) thing contained within the cells than a contractual feature like an interest rate.

    Wait, let's look at Sense 6 synonyms: "hold, bear, contain".
    "Bear" is very common for genes. "He bears the gene for..."

    Let's check if there's any other sense.
    Sense 23: "have or possess something abstract". (No).
    Sense 37: "have with oneself; have on one's person". (No).

    Let's re-read the context: "Mr. Quinlan... knew he carried a damaged gene, having lost an eye to the rare tumor... after his mother had suffered the same fate".
    This emphasizes the hereditary nature.

    If we look at the definition of "carrier" in a medical sense: "a person or organism that possesses a recessive gene for a trait or disease but does not exhibit the trait or disease themselves."

    Does "contain or hold; have within" (Sense 6) fit "possesses"? Yes.
    Does "have as an inherent or characteristic feature" (Sense 36) fit "possesses"? Yes.

    Let's look at the examples for Sense 6 again: "The jar carries wine; The canteen holds fresh water".
    These are very literal containers.

    Let's look at the examples for Sense 36 again: "This new washer carries a two year guarantee; The loan carries a high interest rate".
    These are properties.

    Is a gene a "thing contained" or a "property"?
    Biologically, it's a sequence of DNA (a thing).

    Let's search for "carry" in the sense of "carrying a gene" in other WordNet-based tasks.
    Often, "carry a gene" is associated with "possess" or "contain".

    Let's try to see if Sense 6 is the best fit.
    Sense 6: contain or hold; have within.
    Synonyms: hold, bear, contain.

    This seems the most plausible.

    Wait, let me check Sense 18 again. "transmit or serve as the medium for transmission".
    "The airwaves carry the sound".
    A carrier of a gene *is* the medium for transmission to the next generation.
    But the sentence "he carried a damaged gene" describes his state of possession, not the act of transmission.

    Let's re-verify Sense 6.
    "contain or hold; have within"
    If you carry a gene, you have it within your cells.

    Let's re-verify Sense 36.
    "have as an inherent or characteristic feature"
    A damaged gene is an inherent feature of his genetic code.

    Let's compare "The jar carries wine" (6) and "The loan carries a high interest rate" (36).
    A gene is more like the wine (the content) than the interest rate (the term).

    Let's consider Sense 23: "have or possess something abstract".
    Is a gene abstract? No.

    Let's consider Sense 8: "have on the surface or on the skin".
    No.

    Let's consider Sense 37: "have with oneself; have on one's person".
    No.

    Final check on Sense 6: "contain or hold; have within".
    This seems the most fitting among the choices.

    Wait, let me look at Sense 6 again. "contain or hold; have within".
    And Sense 36: "have as an inherent or characteristic feature".
    Actually, "carrying a gene" is very similar to "carrying a trait".
    If you carry a trait, is it an inherent feature (36) or something you contain (6)?
    It's both, but "inherent feature" (36) sounds more like a description of a trait.
    However, the examples for 36 are "guarantee" and "interest rate", which are not biological traits.

    Let's look at Sense 6 again. "The jar carries wine".
    If we think of the person as the container and the gene as the content, Sense 6 fits.

    Let's double-check if there's any other sense.
    Sense 13: "bear or be able to bear the weight, pressure, or responsibility of". (No).
    Sense 17: "behave in a certain manner". (No).

    Let's think about "carry a disease".
    "He carries the virus."
    This is almost always "contain" or "possess".

    Let's look at Sense 6 again. "contain or hold; have within".
    This seems the most likely.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: damaged
Target surface form: damaged
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a <t>damaged</t> gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=damaged%5:00:00:disreputable:00 | definition=being unjustly brought into disrepute | synonyms=discredited | examples=a discredited politician; her damaged reputation
2. sense_key=damaged%3:00:00:: | definition=harmed or injured or spoiled | examples=I won't buy damaged goods; the storm left a wake of badly damaged buildings

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `damaged`
    *   Target surface form: `damaged`
    *   Context: "Mr. Quinlan, 30 years old, knew he carried a <t>damaged</t> gene..."
    *   Candidate senses:
        1.  `damaged%5:00:00:disreputable:00`: being unjustly brought into disrepute (e.g., discredited politician, damaged reputation).
        2.  `damaged%3:00:00::`: harmed or injured or spoiled (e.g., damaged goods, damaged buildings).

    *   The word "damaged" describes a "gene".
    *   The context discusses cancer, suppressor genes, defective copies, and genetic tests.
    *   A "damaged gene" in this biological context means the gene is mutated, defective, or not functioning correctly (harmed/spoiled in a biological sense).

    *   Sense 1 refers to reputation or social standing (disreputable). This does not fit a gene.
    *   Sense 2 refers to physical harm, injury, or being spoiled. While "damaged goods" or "damaged buildings" are physical objects, the general sense of "harmed or injured or spoiled" applies to the biological structure of a gene (mutation/defect).

    *   Sense 2 is the only logical choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: lose
Target surface form: lost
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having <t>lost</t> an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=lose%2:40:00:: | definition=fail to get or obtain | examples=I lost the opportunity to spend a year abroad
2. sense_key=lose%2:30:03:: | definition=be set at a disadvantage | synonyms=suffer | examples=This author really suffers in translation
3. sense_key=lose%2:39:01:: | definition=fail to perceive or to catch with the senses or the mind | synonyms=miss | examples=I missed that remark; She missed his point
4. sense_key=lose%2:40:02:: | definition=fail to keep or to maintain; cease to have, either physically or in an abstract sense | examples=She lost her purse when she left it unattended on her seat
5. sense_key=lose%2:40:01:: | definition=miss from one's possessions; lose sight of | examples=I've lost my glasses again!
6. sense_key=lose%2:33:00:: | definition=fail to win | examples=We lost the battle but we won the war
7. sense_key=lose%2:35:00:: | definition=place (something) where one cannot find it again | synonyms=misplace, mislay | examples=I misplaced my eyeglasses
8. sense_key=lose%2:33:01:: | definition=retreat | synonyms=fall back, drop off, fall behind, recede
9. sense_key=lose%2:37:00:: | definition=suffer the loss of a person through death or removal | examples=She lost her husband in the war; The couple that wanted to adopt the child lost her when the biological parents claimed her
10. sense_key=lose%2:40:06:: | definition=fail to make money in a business; make a loss or fail to profit | synonyms=turn a loss | examples=I lost thousands of dollars on that bad investment!; The company turned a loss after the first year
11. sense_key=lose%2:39:00:: | definition=allow to go out of sight | examples=The detective lost the man he was shadowing after he had to stop at a red light

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `lose`
    *   Target surface form: `lost`
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having <t>lost</t> an eye to the rare tumor when he was only two months old..."
    *   Meaning: Mr. Quinlan had an eye removed or it was destroyed due to a tumor.

    *   1: fail to get or obtain (e.g., lost opportunity) - No.
    *   2: be set at a disadvantage (e.g., suffer in translation) - No.
    *   3: fail to perceive or to catch (e.g., missed a remark) - No.
    *   4: fail to keep or to maintain; cease to have, either physically or in an abstract sense (e.g., lost her purse) - Possible, but usually implies accidental loss or failure to maintain.
    *   5: miss from one's possessions; lose sight of (e.g., lost glasses) - No.
    *   6: fail to win (e.g., lost the battle) - No.
    *   7: place where one cannot find it again (e.g., misplaced eyeglasses) - No.
    *   8: retreat (e.g., fall back) - No.
    *   9: suffer the loss of a person through death or removal (e.g., lost her husband in the war) - This sense mentions "removal". While the example is a person, the definition "suffer the loss of a person through death or removal" is close, but the target is an eye. Wait, let me re-read. "Suffer the loss of a person through death or removal". An eye is not a person.
    *   10: fail to make money (e.g., lost thousands of dollars) - No.
    *   11: allow to go out of sight (e.g., lost the man he was shadowing) - No.

    *   Sense 4: "fail to keep or to maintain; cease to have, either physically or in an abstract sense".
    *   Sense 9: "suffer the loss of a person through death or removal".

    Wait, let me look at Sense 4 again: "fail to keep or to maintain; cease to have, either physically or in an abstract sense".
    Example: "She lost her purse when she left it unattended on her seat".

    Is there a better sense? Let's re-examine Sense 9. "suffer the loss of a person through death or removal". The "removal" part is interesting, but it specifically says "of a person".

    Let's look at Sense 4 again. "cease to have, either physically or in an abstract sense". Losing an eye (due to surgery or disease) fits "cease to have physically".

    Let's double-check if there are other senses of "lose" in WordNet that might fit better.
    Looking at the provided list:
    1. fail to get
    2. be set at a disadvantage
    3. fail to perceive
    4. fail to keep or maintain; cease to have
    5. miss from possessions
    6. fail to win
    7. misplace
    8. retreat
    9. suffer loss of a person
    10. fail to make money
    11. allow to go out of sight

    Comparing Sense 4 and Sense 9:
    Sense 4 is general: "cease to have, either physically or in an abstract sense".
    Sense 9 is specific to people: "suffer the loss of a person through death or removal".

    Since an eye is not a person, Sense 4 is the most appropriate fit among the choices provided.

    Wait, let me think about "lost an eye". Does "fail to keep or maintain" sound right?
    "Cease to have" definitely fits. If you lose an eye to a tumor, you cease to have it.

    Let's check if "lost" in "lost an eye" is often categorized under "cease to have".
    Yes, in many lexical databases, losing a limb or an organ is categorized as "ceasing to have" or "deprivation".

    Let's re-read Sense 4: "fail to keep or to maintain; cease to have, either physically or in an abstract sense".
    Example: "She lost her purse when she left it unattended on her seat". (This is more "fail to keep").
    But "cease to have" covers the loss of a body part.

    Let's re-read Sense 9: "suffer the loss of a person through death or removal".
    Example: "She lost her husband in the war".
    If the definition was "suffer the loss of something/someone through death or removal", it would be perfect. But it says "of a person".

    Therefore, Sense 4 is the best fit.

    Wait, let me look at the examples for Sense 4 again. "She lost her purse when she left it unattended on her seat". This is more like misplacing or losing possession.
    Is there any other sense?
    Sense 5: "miss from one's possessions; lose sight of". (Similar to 4).
    Sense 7: "place (something) where one cannot find it again". (Misplace).

    Let's reconsider Sense 4: "fail to keep or to maintain; cease to have, either physically or in an abstract sense".
    If you lose an eye, you cease to have it physically. This fits.

    Let's double-check if "lose" in "lose a limb" is usually Sense 4.
    In WordNet 3.0, `lose` (verb) has several senses.
    One is "fail to keep or maintain; cease to have" (lose%2:40:02).
    Another is "suffer the loss of a person through death or removal" (lose%2:37:00).

    If the target is "lost an eye", it's not a person. So Sense 4 is the only one that fits "cease to have physically".

    Sense 4: fail to keep or to maintain; cease to have, either physically or in an abstract sense.
    Context: "lost an eye to the rare tumor".
    Result: Ceased to have the eye physically.

    Sense 9: suffer the loss of a person through death or removal.
    Context: "lost an eye".
    Result: An eye is not a person.

    Sense 4 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: eye
Target surface form: eye
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an <t>eye</t> to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=eye%1:09:00:: | definition=good discernment (either visually or as if visually) | examples=she has an eye for fresh talent; he has an artist's eye
2. sense_key=eye%1:08:00:: | definition=the organ of sight | synonyms=oculus, optic
3. sense_key=eye%1:06:00:: | definition=a small hole or loop (as in a needle) | examples=the thread wouldn't go through the eye
4. sense_key=eye%1:15:00:: | definition=an area that is approximately central within some larger region | synonyms=center, centre, middle, heart | examples=it is in the center of town; they ran forward into the heart of the struggle
5. sense_key=eye%1:09:01:: | definition=attention to what is seen | examples=he tried to catch her eye

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `eye`
    *   Target surface form: `eye`
    *   Context: "...having lost an <t>eye</t> to the rare tumor when he was only two months old..."
    *   Candidate senses:
        1.  `eye%1:09:00::`: good discernment (e.g., "eye for fresh talent")
        2.  `eye%1:08:00::`: the organ of sight (synonyms: oculus, optic)
        3.  `eye%1:06:00::`: a small hole or loop (e.g., "eye of a needle")
        4.  `eye%1:15:00::`: an area that is approximately central (synonyms: center, heart)
        5.  `eye%1:09:01::`: attention to what is seen (e.g., "catch her eye")

    *   The sentence says: "Mr. Quinlan... knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old..."
    *   The "rare tumor" mentioned is "retinoblastoma, an eye cancer".
    *   Losing an "eye" to "eye cancer" clearly refers to the physical organ of sight.

    *   Sense 1: Discernment (Incorrect)
    *   Sense 2: Organ of sight (Correct)
    *   Sense 3: Small hole/loop (Incorrect)
    *   Sense 4: Central area (Incorrect)
    *   Sense 5: Attention (Incorrect)

    *   The best sense is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was <t>only</t> two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
2. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
3. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
4. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
5. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
6. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: "only"
    *   Target surface form: "only"
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was <t>only</t> two months old..."

    *   Sense 1: `never except when` (only if/when) - Not applicable.
    *   Sense 2: `in the final outcome` (e.g., "will only make you more upset") - Not applicable.
    *   Sense 3: `except that` (e.g., "only this time she came out better") - Not applicable.
    *   Sense 4: `with nevertheless the final result` (e.g., "arrived only to find") - Not applicable.
    *   Sense 5: `without any others being included or involved` (entirely, exclusively, solely) - Not applicable.
    *   Sense 6: `and nothing more` (merely, simply, just, but) - "when he was *just* two months old" or "when he was *merely* two months old". This fits the context of emphasizing a small age.
    *   Sense 7: `as recently as` (e.g., "I spoke to him only an hour ago") - This refers to time elapsed from the present or a reference point. "Only two months old" describes the age at the time of the event, not how recently it happened relative to now.

    *   The sentence says "when he was only two months old".
    *   This is used to emphasize that the age was very young (small amount).
    *   Synonyms for this usage: "just", "merely", "simply".
    *   Sense 6 definition: "and nothing more" (synonyms: merely, simply, just). This fits perfectly.

    *   Sense 7 ("as recently as") is usually used for time intervals (e.g., "only two days ago").
    *   Sense 6 ("merely/just") is used for quantities or ages (e.g., "only five years old").

    *   Sense 6 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: mother
Target surface form: mother
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his <t>mother</t> had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=mother%1:18:02:: | definition=a term of address for an elderly woman
2. sense_key=mother%1:18:00:: | definition=a woman who has given birth to a child (also used as a term of address to your mother) | synonyms=female parent | examples=the mother of three children
3. sense_key=mother%1:27:00:: | definition=a stringy slimy substance consisting of yeast cells and bacteria; forms during fermentation and is added to cider or wine to produce vinegar
4. sense_key=mother%1:18:01:: | definition=a term of address for a mother superior
5. sense_key=mother%1:09:00:: | definition=a condition that is the inspiration for an activity or situation | examples=necessity is the mother of invention

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "mother"
    *   Target surface form: "mother"
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his <t>mother</t> had suffered the same fate when she was a baby."
    *   Candidate senses:
        1.  Term of address for an elderly woman.
        2.  A woman who has given birth to a child (female parent).
        3.  A stringy slimy substance (fermentation).
        4.  Term of address for a mother superior.
        5.  A condition that is the inspiration for an activity (e.g., "mother of invention").

    *   The sentence says "his mother had suffered the same fate".
    *   "His" refers to Mr. Quinlan.
    *   The context is about genetic inheritance (damaged gene, retinoblastoma).
    *   The "mother" in this context is the female parent of Mr. Quinlan.

    *   Sense 1: Elderly woman (incorrect).
    *   Sense 2: Woman who has given birth to a child / female parent (correct).
    *   Sense 3: Fermentation substance (incorrect).
    *   Sense 4: Mother superior (incorrect).
    *   Sense 5: Inspiration/condition (incorrect).

    *   The best fit is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: suffer
Target surface form: suffered
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had <t>suffered</t> the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=suffer%2:29:01:: | definition=undergo (as of injuries and illnesses) | synonyms=sustain, have, get | examples=She suffered a fracture in the accident; He had an insulin shock after eating three candy bars
2. sense_key=suffer%2:30:00:: | definition=get worse | examples=His grades suffered
3. sense_key=suffer%2:37:00:: | definition=experience (emotional) pain | examples=Every time her husband gets drunk, she suffers
4. sense_key=suffer%2:31:00:: | definition=put up with something or somebody unpleasant | synonyms=digest, endure, stick out, stomach, bear, stand | examples=I cannot bear his constant criticism; The new secretary had to endure a lot of unprofessional remarks
5. sense_key=suffer%2:30:02:: | definition=be set at a disadvantage | synonyms=lose | examples=This author really suffers in translation
6. sense_key=suffer%2:39:00:: | definition=feel physical pain | synonyms=hurt, ache | examples=Were you hurting after the accident?
7. sense_key=suffer%2:39:01:: | definition=undergo or be subjected to | synonyms=endure | examples=He suffered the penalty; Many saints suffered martyrdom
8. sense_key=suffer%2:42:04:: | definition=be given to | examples=She suffers from a tendency to talk too much
9. sense_key=suffer%2:29:00:: | definition=feel pain or be in pain | synonyms=hurt
10. sense_key=suffer%2:29:03:: | definition=feel unwell or uncomfortable | examples=She is suffering from the hot weather
11. sense_key=suffer%2:39:02:: | definition=undergo or suffer | synonyms=meet | examples=meet a violent death; suffer a terrible fate

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 11}
```

content:
```json
{"sense_index": 11}
```

reasoning_content:
*   Target lemma: `suffer`
    *   Target surface form: `suffered`
    *   Context: "...Mr. Quinlan... knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had <t>suffered</t> the same fate when she was a baby."

    *   The phrase is "suffered the same fate".
    *   The "fate" refers to "having lost an eye to the rare tumor".
    *   So, the mother also lost an eye to the rare tumor.

    *   Sense 1: undergo (as of injuries and illnesses) - *Possible, but "fate" is more general than just an illness.*
    *   Sense 2: get worse - *Incorrect.*
    *   Sense 3: experience (emotional) pain - *Incorrect.*
    *   Sense 4: put up with something or somebody unpleasant - *Incorrect.*
    *   Sense 5: be set at a disadvantage - *Incorrect.*
    *   Sense 6: feel physical pain - *Incorrect.*
    *   Sense 7: undergo or be subjected to (e.g., penalty, martyrdom) - *Possible.*
    *   Sense 8: be given to - *Incorrect.*
    *   Sense 9: feel pain or be in pain - *Incorrect.*
    *   Sense 10: feel unwell or uncomfortable - *Incorrect.*
    *   Sense 11: undergo or suffer (synonym: meet) - *Examples: "meet a violent death; suffer a terrible fate".*

    *   Sense 11 specifically lists "suffer a terrible fate" as an example.
    *   The context is "suffered the same fate".
    *   Sense 7 is "undergo or be subjected to" (penalty, martyrdom).
    *   Sense 11 is "undergo or suffer" (meet a violent death, suffer a terrible fate).

    *   The phrase "suffered the same fate" matches the example in Sense 11 ("suffer a terrible fate") almost perfectly.

    *   Sense 11: `suffer%2:39:02:: | definition=undergo or suffer | synonyms=meet | examples=meet a violent death; suffer a terrible fate`
    *   This is the most precise match for the collocation "suffered the same fate".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: same
Target surface form: same
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the <t>same</t> fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=same%3:00:02:: | definition=same in identity | examples=the same man I saw yesterday; never wore the same dress twice
2. sense_key=same%3:00:00:: | definition=closely similar or comparable in kind or quality or quantity or degree | examples=curtains the same color as the walls; two girls of the same age
3. sense_key=same%5:00:00:unchanged:00 | definition=unchanged in character or nature | examples=the village stayed the same; his attitude is the same as ever
4. sense_key=same%3:00:04:: | definition=equal in amount or value | synonyms=like | examples=like amounts; equivalent amounts

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "same"
    *   Target surface form: "same"
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the <t>same</t> fate when she was a baby."
    *   Candidate senses:
        1.  `same%3:00:02::`: same in identity (e.g., the same man).
        2.  `same%3:00:00::`: closely similar or comparable in kind or quality or quantity or degree (e.g., curtains the same color).
        3.  `same%5:00:00:unchanged:00`: unchanged in character or nature (e.g., the village stayed the same).
        4.  `same%3:00:04::`: equal in amount or value (e.g., like amounts).

    *   The sentence says: "Mr. Quinlan... having lost an eye to the rare tumor... after his mother had suffered the same fate..."
    *   "The same fate" refers to the experience of losing an eye to the rare tumor.
    *   Did the mother and son share the *exact same event* (identity)? No. They had separate events (two different people losing eyes at different times).
    *   Was the fate *unchanged* over time? No, that's not the meaning here.
    *   Was the fate *equal in amount or value*? No.
    *   Was the fate *closely similar or comparable in kind*? Yes. Both suffered the "fate" of losing an eye to the same type of tumor.

    *   Sense 1 (Identity): "the same man I saw yesterday" (one specific man). Not applicable here because the mother and son are different people experiencing separate events.
    *   Sense 2 (Similar/Comparable): "curtains the same color as the walls" (similar quality). "The same fate" is a common idiom meaning a similar or identical *kind* of experience.
    *   Sense 3 (Unchanged): "the village stayed the same". Not applicable.
    *   Sense 4 (Equal amount): "like amounts". Not applicable.

    *   The phrase "the same fate" almost always refers to a similar outcome or experience, not the identical event. Therefore, Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: fate
Target surface form: fate
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same <t>fate</t> when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=fate%1:11:00:: | definition=an event (or a course of events) that will inevitably happen in the future | synonyms=destiny
2. sense_key=fate%1:18:00:: | definition=the ultimate agency regarded as predetermining the course of events (often personified as a woman) | synonyms=destiny | examples=we are helpless in the face of destiny
3. sense_key=fate%1:26:00:: | definition=your overall circumstances or condition in life (including everything that happens to you) | synonyms=fortune, destiny, luck, lot, circumstances, portion | examples=whatever my fortune may be; deserved a better fate

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `fate`
    *   Target surface form: `fate`
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same <t>fate</t> when she was a baby."
    *   Candidate senses:
        1.  `fate%1:11:00`: an event (or a course of events) that will inevitably happen in the future (synonym: destiny).
        2.  `fate%1:18:00`: the ultimate agency regarded as predetermining the course of events (synonym: destiny).
        3.  `fate%1:26:00`: your overall circumstances or condition in life (including everything that happens to you) (synonyms: fortune, destiny, luck, lot, circumstances, portion).

    *   The sentence says: "...having lost an eye to the rare tumor... after his mother had suffered the same fate..."
    *   "The same fate" refers back to "lost an eye to the rare tumor".
    *   In this context, "fate" refers to a specific outcome or event (losing an eye to a tumor) that happened to both the son and the mother.

    *   Sense 1: "an event (or a course of events) that will inevitably happen in the future". While "inevitably" might be strong, in common usage, "suffering the same fate" often refers to a specific negative outcome or event.
    *   Sense 2: "the ultimate agency regarded as predetermining the course of events". This is the personification of Fate (e.g., the Three Fates). Not applicable here.
    *   Sense 3: "your overall circumstances or condition in life". This is too broad. Losing an eye is a specific event, not a general "condition in life" or "overall circumstances".

    *   Wait, let me re-examine Sense 1 and Sense 3.
    *   Sense 1: "an event (or a course of events) that will inevitably happen in the future".
    *   Sense 3: "your overall circumstances or condition in life (including everything that happens to you)".
    *   Actually, looking at common WordNet usage for "suffered the same fate", it usually maps to the "event/outcome" sense.
    *   Let's look at the examples for Sense 3: "whatever my fortune may be; deserved a better fate". These are more about general lot in life.
    *   Let's look at Sense 1 again: "an event (or a course of events) that will inevitably happen in the future".
    *   Is losing an eye an "event"? Yes. Was it "inevitable"? In the context of genetic predisposition, it's presented as a high risk/likelihood.
    *   Let's check if there's another sense of "fate" often used for "outcome".
    *   In many dictionaries, "fate" means "the development of events with specified outcomes" or "a particular outcome".
    *   Comparing Sense 1 and Sense 3 again:
        *   Sense 1: "an event... that will inevitably happen".
        *   Sense 3: "overall circumstances or condition in life".
    *   "Suffered the same fate" almost always refers to a specific outcome (like death, injury, or failure).
    *   If I have to choose between "an event" (1) and "overall circumstances" (3), "an event" is much closer to "losing an eye".

    *   Sense 1: "an event (or a course of events) that will inevitably happen in the future".
    *   Sense 3: "your overall circumstances or condition in life (including everything that happens to you)".
    *   If someone says "He suffered the same fate as his father," they usually mean he experienced the same specific outcome (e.g., went bankrupt, died young). This fits "an event" better than "overall circumstances".

    *   Sense 1: fate%1:11:00
    *   Sense 2: fate%1:18:00
    *   Sense 3: fate%1:26:00
    *   The target is "the same fate" (losing an eye). This is a specific event/outcome.

    *   Wait, let me double-check if "fate" as "outcome" is better captured by Sense 1 or Sense 3.
    *   Sense 1: "an event... that will inevitably happen".
    *   Sense 3: "overall circumstances... (including everything that happens to you)".
    *   Actually, looking at other WordNet-based datasets, "suffered the same fate" often maps to the sense of "destiny" or "outcome".
    *   Let's re-read Sense 1: "an event (or a course of events) that will inevitably happen in the future".
    *   Let's re-read Sense 3: "your overall circumstances or condition in life (including everything that happens to you)".
    *   If the "fate" is "losing an eye", that is a specific event. Sense 1 describes an event. Sense 3 describes a general condition.

    *   Is "losing an eye" an "inevitable event"? In the context of the story, it's a genetic predisposition, so it's presented as a likely/inevitable outcome for those with the gene.
    *   Is "losing an eye" a "condition in life"? It's a result of an event, but "the same fate" refers to the event of losing the eye.

    *   Sense 1: event/destiny.
    *   Sense 3: fortune/lot.
    *   "Suffered the same fate" -> "Suffered the same outcome/event".
    *   This aligns best with Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: baby
Target surface form: baby
Context:
Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a <t>baby</t>. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Candidate senses:
1. sense_key=baby%1:18:00:: | definition=a very young child (birth to 1 year) who has not yet begun to walk or talk | synonyms=babe, infant | examples=the baby began to cry again; she held the baby in her arms
2. sense_key=baby%1:18:03:: | definition=an immature childish person | synonyms=child | examples=he remained a child in practical matters as long as he lived; stop being a baby!
3. sense_key=baby%1:18:01:: | definition=the youngest member of a group (not necessarily young) | examples=the baby of the family; the baby of the Supreme Court
4. sense_key=baby%1:04:00:: | definition=a project of personal concern to someone | examples=this project is his baby
5. sense_key=baby%1:18:02:: | definition=(slang) sometimes used as a term of address for attractive young women | synonyms=babe, sister
6. sense_key=baby%1:18:04:: | definition=an unborn child; a human fetus | examples=I felt healthy and very feminine carrying the baby; it was great to feel my baby moving about inside
7. sense_key=baby%1:05:00:: | definition=a very young mammal | examples=baby rabbits

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `baby`
    *   Target surface form: `baby`
    *   Context: "...Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a <t>baby</t>."
    *   Candidate senses:
        1.  `baby%1:18:00`: a very young child (birth to 1 year) who has not yet begun to walk or talk.
        2.  `baby%1:18:03`: an immature childish person.
        3.  `baby%1:18:01`: the youngest member of a group.
        4.  `baby%1:04:00`: a project of personal concern.
        5.  `baby%1:18:02`: (slang) term of address for attractive young women.
        6.  `baby%1:18:04`: an unborn child; a human fetus.
        7.  `baby%1:05:00`: a very young mammal.

    *   The sentence says: "...after his mother had suffered the same fate when she was a baby."
    *   The "same fate" refers to losing an eye to a rare tumor (retinoblastoma).
    *   The context mentions Mr. Quinlan lost his eye when he was "two months old".
    *   The mother also suffered this when she was a "baby".
    *   This clearly refers to the stage of early childhood (infancy).

    *   Sense 1: "a very young child (birth to 1 year)..." - Fits perfectly.
    *   Sense 2: "an immature childish person" - Does not fit.
    *   Sense 3: "the youngest member of a group" - Does not fit.
    *   Sense 4: "a project of personal concern" - Does not fit.
    *   Sense 5: "term of address for attractive young women" - Does not fit.
    *   Sense 6: "an unborn child; a human fetus" - While possible for some medical conditions, the context of "suffered the same fate" (losing an eye) usually happens after birth, and the parallel with "two months old" strongly points to Sense 1.
    *   Sense 7: "a very young mammal" - Too general; Sense 1 is specific to humans.

    *   The most accurate sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: isolation
Target surface form: isolation
Context:
A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the <t>isolation</t> of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Candidate senses:
1. sense_key=isolation%1:04:01:: | definition=a country's withdrawal from international politics | examples=he opposed a policy of American isolation
2. sense_key=isolation%1:26:00:: | definition=a state of separation between persons or groups
3. sense_key=isolation%1:22:00:: | definition=(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
4. sense_key=isolation%1:04:00:: | definition=the act of isolating something; setting something apart from others | synonyms=closing off
5. sense_key=isolation%1:12:00:: | definition=a feeling of being disliked and alone

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: "isolation"
    *   Context: "Because of the <t>isolation</t> of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced."
    *   Meaning: In this scientific/medical context, "isolation" refers to the process of identifying and separating a specific gene (the retinoblastoma tumor-suppressor gene) from the rest of the genetic material so it can be studied or used for testing.

    *   Sense 1: "a country's withdrawal from international politics" (Political isolation) - Incorrect.
    *   Sense 2: "a state of separation between persons or groups" (Social isolation) - Incorrect.
    *   Sense 3: "(psychiatry) a defense mechanism..." (Psychological isolation) - Incorrect.
    *   Sense 4: "the act of isolating something; setting something apart from others" (General act of isolating/separating) - Correct. In biology/chemistry, "isolating a gene" means separating it from others.
    *   Sense 5: "a feeling of being disliked and alone" (Emotional isolation) - Incorrect.

    *   The context describes the scientific discovery/separation of a specific gene.
    *   Sense 4 ("the act of isolating something; setting something apart from others") fits perfectly as the general definition covering the scientific process of isolation.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: become
Target surface form: became
Context:
A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it <t>became</t> possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Candidate senses:
1. sense_key=become%2:30:00:: | definition=enter or assume a certain state or condition | synonyms=go, get | examples=He became annoyed when he heard the bad news; It must be getting more serious
2. sense_key=become%2:42:01:: | definition=undergo a change or development | synonyms=turn | examples=The water turned into ice; Her former friend became her worst enemy
3. sense_key=become%2:42:03:: | definition=enhance the appearance of | synonyms=suit | examples=Mourning becomes Electra; This behavior doesn't suit you!
4. sense_key=become%2:42:00:: | definition=come into existence | examples=What becomes has duration

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `become`
    *   Target surface form: `became`
    *   Context: "Because of the isolation of the retinoblastoma tumor-suppressor gene, it <t>became</t> possible last January to find out what threat the Quinlan baby faced."

    *   Sense 1: `become%2:30:00::` - enter or assume a certain state or condition (Synonyms: go, get; Example: "He became annoyed").
    *   Sense 2: `become%2:42:01::` - undergo a change or development (Synonyms: turn; Example: "The water turned into ice").
    *   Sense 3: `become%2:42:03::` - enhance the appearance of (Synonyms: suit; Example: "Mourning becomes Electra").
    *   Sense 4: `become%2:42:00::` - come into existence (Example: "What becomes has duration").

    *   The sentence is: "...it became possible last January to find out..."
    *   Here, "became" is used with the adjective "possible".
    *   This describes a change in state (from not being possible to being possible).
    *   Sense 1 ("enter or assume a certain state or condition") fits perfectly. "It became possible" is analogous to "He became annoyed" (entering a state of annoyance).
    *   Sense 2 ("undergo a change or development") often implies a transformation into something else (e.g., water to ice, friend to enemy). While "becoming possible" is a change, Sense 1 is the standard usage for "become + adjective".
    *   Sense 3 ("enhance the appearance of") is clearly incorrect.
    *   Sense 4 ("come into existence") refers to the philosophical concept of becoming vs. being.

    *   "It became possible" $\rightarrow$ "It entered the state of being possible."
    *   This aligns with Sense 1.