[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spread
Target surface form: spread
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=spread%2:35:00:: | definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. sense_key=spread%2:35:12:: | definition=cover by spreading something over | examples=spread the bread with cheese
3. sense_key=spread%2:32:02:: | definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
4. sense_key=spread%2:38:02:: | definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
5. sense_key=spread%2:32:00:: | definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. sense_key=spread%2:35:13:: | definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread
7. sense_key=spread%2:38:00:: | definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. sense_key=spread%2:42:00:: | definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
9. sense_key=spread%2:35:03:: | definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
10. sense_key=spread%2:35:07:: | definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 10}
```

content:
```json
{"sense_index": 10}
```

reasoning_content:
*   Target lemma: `spread`
    *   Target surface form: `spread`
    *   Context: "...malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body)..."
    *   Meaning: In the context of cancer (malignancy), "spread" refers to the movement of cancer cells from the primary site to other parts of the body (metastasis).

    *   1: distribute or disperse widely (e.g., language)
    *   2: cover by spreading something over (e.g., bread with cheese)
    *   3: become widely known and passed on (e.g., rumor)
    *   4: move outward (e.g., soldiers fanning out)
    *   5: cause to become widely known (e.g., information)
    *   6: distribute over a surface in a layer (e.g., cheese on bread)
    *   7: strew or distribute over an area (e.g., fertilizer)
    *   8: spread across or over (e.g., oil spot)
    *   9: spread out or open from a closed or folded state (e.g., map)
    *   10: become distributed or widespread (e.g., infection)

    *   The context is medical (cancer).
    *   "Malignant (has spread... to other parts of the body)".
    *   Sense 10: "become distributed or widespread" with the example "the infection spread". Cancer metastasis is very similar to an infection spreading throughout the body.
    *   Sense 8: "spread across or over" (oil spot) is more about surface area.
    *   Sense 4: "move outward" (soldiers) is more about tactical movement.
    *   Sense 1: "distribute or disperse widely" (language) is more about cultural/social distribution.

    *   Sense 10 specifically mentions "the infection spread", which is the closest analog to cancer spreading (metastasis).

    *   Sense 10: "become distributed or widespread" (synonym: propagate; example: "the infection spread"). This fits the biological/medical context of cancer cells moving to other parts of the body.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: likely
Target surface form: likely
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=likely%5:00:00:credible:00 | definition=within the realm of credibility | examples=not a very likely excuse
2. sense_key=likely%3:00:00:: | definition=has a good chance of being the case or of coming about | examples=these services are likely to be available to us all before long; she is likely to forget
3. sense_key=likely%3:00:04:: | definition=likely but not certain to be or become true or real | synonyms=probable | examples=a likely result; he foresaw a probable loss
4. sense_key=likely%5:00:00:prospective:00 | definition=expected to become or be; in prospect | synonyms=potential | examples=potential clients

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

finish_reason: stop

content:
```json
{"sense_index": 2}
```

role: assistant

reasoning_content:
*   Target lemma: `likely`
    *   Target surface form: `likely`
    *   Context: "...malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body)..."
    *   Candidate senses:
        1.  `credible` (within the realm of credibility) - e.g., "not a very likely excuse".
        2.  `has a good chance of being the case or of coming about` - e.g., "these services are likely to be available", "she is likely to forget".
        3.  `likely but not certain to be or become true or real` (probable) - e.g., "a likely result".
        4.  `prospective` (expected to become or be; in prospect) - e.g., "potential clients".

    *   The phrase is "is likely to spread easily".
    *   This describes a probability or a tendency for the cancer to spread.
    *   It's not about credibility (Sense 1).
    *   It's not about being a "prospective" entity (Sense 4).
    *   It's between Sense 2 and Sense 3.

    *   Sense 2: "has a good chance of being the case or of coming about" (often used as a predicate adjective: "X is likely to Y").
    *   Sense 3: "likely but not certain to be or become true or real" (often used as an attributive adjective: "a likely result").

    *   In the sentence "is likely to spread", "likely" is used as a predicate adjective following the verb "is".
    *   Example for Sense 2: "she is likely to forget". This matches the syntactic structure "is likely to [verb]".
    *   Example for Sense 3: "a likely result". This is an attributive use.

    *   Sense 2 fits the grammatical structure ("is likely to spread") and the meaning (probability of an event occurring).

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spread
Target surface form: spread
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=spread%2:35:07:: | definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
2. sense_key=spread%2:32:00:: | definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
3. sense_key=spread%2:35:03:: | definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
4. sense_key=spread%2:35:12:: | definition=cover by spreading something over | examples=spread the bread with cheese
5. sense_key=spread%2:38:00:: | definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
6. sense_key=spread%2:32:02:: | definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. sense_key=spread%2:42:00:: | definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
8. sense_key=spread%2:38:02:: | definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. sense_key=spread%2:35:13:: | definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread
10. sense_key=spread%2:35:00:: | definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `spread`
    *   Target surface form: `spread`
    *   Context: "...malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body)..."
    *   Meaning: In the context of cancer (malignancy), "spread" refers to the movement of cancer cells from the primary site to other parts of the body (metastasis).

    *   Sense 1: `become distributed or widespread` (Synonyms: propagate; Examples: "the infection spread", "Optimism spread among the population").
    *   Sense 2: `cause to become widely known` (Synonyms: circulate, disseminate; Examples: "spread information").
    *   Sense 3: `spread out or open from a closed or folded state` (Synonyms: unfold; Examples: "open the map").
    *   Sense 4: `cover by spreading something over` (Example: "spread the bread with cheese").
    *   Sense 5: `strew or distribute over an area` (Synonyms: scatter; Example: "spread fertilizer over the lawn").
    *   Sense 6: `become widely known and passed on` (Synonyms: go around; Example: "the rumor spread").
    *   Sense 7: `spread across or over` (Synonyms: overspread; Example: "A big oil spot spread across the water").
    *   Sense 8: `move outward` (Synonyms: diffuse, fan out; Example: "The soldiers fanned out").
    *   Sense 9: `distribute over a surface in a layer` (Example: "spread cheese on a piece of bread").
    *   Sense 10: `distribute or disperse widely` (Synonyms: distribute; Example: "The invaders spread their language").

    *   The context is medical: cancer spreading to other parts of the body.
    *   Sense 1 ("become distributed or widespread") specifically lists "the infection spread" as an example. Cancer metastasis is very similar to the spread of an infection in terms of biological distribution throughout the body.
    *   Sense 7 ("spread across or over") is more about surface area (like an oil spot).
    *   Sense 8 ("move outward") is more about physical movement/formation (like soldiers).
    *   Sense 10 ("distribute or disperse widely") is usually an active process (like invaders spreading a language).

    *   Sense 1: "become distributed or widespread" (Example: "the infection spread"). This fits the biological context of cancer cells moving and establishing themselves in other organs.

    *   Sense 1: `become distributed or widespread` (Example: "the infection spread").
    *   Context: "malignant (has spread, or is likely to spread easily, to other parts of the body)".
    *   This is a perfect match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: easily
Target surface form: easily
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster
2. sense_key=easily%4:02:01:: | definition=with ease (`easy' is sometimes used informally for `easily') | synonyms=easy | examples=she was easily excited; was easily confused
3. sense_key=easily%4:02:06:: | definition=without question | examples=easily the best book she's written

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "easily"
    *   Target surface form: "easily"
    *   Context: "...malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body)..."
    *   Candidate senses:
        1.  `easily%4:02:05::`: indicating high probability; in all likelihood (e.g., "could easily have ended in disaster").
        2.  `easily%4:02:01::`: with ease (e.g., "she was easily excited").
        3.  `easily%4:02:06::`: without question (e.g., "easily the best book").

    *   The phrase is "likely to spread easily".
    *   In a medical context, "spread easily" refers to the ease with which cancer cells migrate or metastasize. It means the process happens without much resistance or difficulty.

    *   Sense 1 (high probability): "likely to spread easily" would be redundant if "easily" meant "likely". "Likely to spread in all likelihood" doesn't make sense.
    *   Sense 2 (with ease): "likely to spread with ease". This fits perfectly. It describes the manner of spreading (without difficulty/resistance).
    *   Sense 3 (without question): "likely to spread without question". This doesn't fit the context of biological spread.

    *   Sense 2 is the most appropriate.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail
2. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
3. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
4. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: "other"
    *   Target surface form: "other"
    *   Context: "...malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body)..."
    *   Candidate senses:
        1.  `other%5:00:00:strange:00`: very unusual; different in character or quality from the normal or expected.
        2.  `other%5:00:02:past:00`: belonging to the distant past.
        3.  `other%5:00:00:past:00`: recently past.
        4.  `other%3:00:00::`: not the same one or ones already mentioned or implied.

    *   The phrase is "other parts of the body".
    *   In this context, "other" refers to parts of the body that are different from the original site of the cancer (the lungs/pleural mesothelioma).
    *   It means "additional" or "different from the one(s) already mentioned".

    *   Sense 1 (strange/unusual): Does not fit. The parts of the body aren't "strange" or "unusual".
    *   Sense 2 (distant past): Does not fit.
    *   Sense 3 (recently past): Does not fit.
    *   Sense 4 (not the same one or ones already mentioned): Fits perfectly. The cancer spreads from the primary site to *other* (different/additional) parts of the body.

    *   Sense 4 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: parts
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work
2. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
3. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
4. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
5. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
6. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
7. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
8. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
9. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
12. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `part`
    *   Target surface form: `parts`
    *   Context: "...malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body)..."

    *   1: Contribution/share in bringing about a result. (Incorrect)
    *   2: Extended spatial location/region (e.g., "parts of the world"). (Possible)
    *   3: Assets/share/portion. (Incorrect)
    *   4: Something less than the whole of a human artifact. (Incorrect - body is not a human artifact)
    *   5: One of the portions into which something is regarded as divided (section, division). (Possible)
    *   6: Something determined in relation to something that includes it (component part). (Possible)
    *   7: A portion of a natural object (piece). (Possible - the body is a natural object)
    *   8: Actor's portrayal. (Incorrect)
    *   9: Melody in music. (Incorrect)
    *   10: Line of scalp. (Incorrect)
    *   11: Actions/activities assigned to a person (role). (Incorrect)
    *   12: That which concerns a person (vigilance on our part). (Incorrect)

    *   The phrase is "other parts of the body".
    *   Sense 2: "the extended spatial location of something" (synonym: region). Example: "religions in all parts of the world". This fits well with anatomical regions.
    *   Sense 5: "one of the portions into which something is regarded as divided" (synonym: section, division).
    *   Sense 7: "a portion of a natural object" (synonym: piece). Example: "analyzed the river into three parts".

    *   Sense 2 (region) is often used for geographical or anatomical areas (e.g., "parts of the body").
    *   Sense 7 (piece) usually implies a physical fragment or a distinct piece of a natural object (like a piece of granite).
    *   Sense 5 (section/division) is more about conceptual or structural divisions.

    Let's re-examine Sense 2: "the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world".
    If we replace "parts" with "regions" in "other regions of the body", it makes perfect sense.

    Let's re-examine Sense 7: "a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite".
    "Other pieces of the body" sounds like the body has been cut up.

    Let's re-examine Sense 5: "one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division".
    "Other sections of the body" is possible, but "parts of the body" usually refers to regions/areas.

    Comparing Sense 2 and Sense 5:
    Sense 2 specifically mentions "extended spatial location" and "region".
    Sense 5 is more general about divisions.

    In medical contexts, "parts of the body" usually refers to anatomical regions.

    Wait, let me look at Sense 2 again. "the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world".
    This seems to fit the "spatial" aspect of the body.

    Let's check if there's a better fit.
    Sense 6: "something determined in relation to something that includes it | synonyms=portion, component part, component, constituent".
    "Other components of the body"? Not quite.

    Let's look at Sense 2 again. "the extended spatial location of something".
    If I say "the upper parts of the body", I'm talking about regions.

    Let's double-check Sense 7 again. "a portion of a natural object".
    Is the body a natural object? Yes. Is a "part" of the body a "portion" of it? Yes.
    But "piece" (synonym for Sense 7) is usually a fragment.

    Let's look at Sense 2's synonym "region". "Other regions of the body" is a very common way to describe cancer spreading.

    Wait, let me search for "parts of the body" in WordNet-like contexts.
    Usually, "parts of the body" refers to organs or regions.
    If it's organs, it might be "component parts" (Sense 6).
    If it's regions, it's Sense 2.

    Let's re-read the context: "malignant (has spread, or is likely to spread easily, to other parts of the body)".
    This refers to metastasis. Metastasis happens to other organs or other regions.

    Let's compare Sense 2 and Sense 5 again.
    Sense 2: extended spatial location / region.
    Sense 5: portion into which something is regarded as divided / section.

    "Parts of the world" (Sense 2) is very similar to "parts of the body".

    Let's check Sense 7 again: "a portion of a natural object".
    Example: "they analyzed the river into three parts".
    A river is a natural object. A body is a natural object.
    But "piece of granite" suggests a fragment.

    Let's look at Sense 2 again. "the extended spatial location of something".
    This fits the idea of "areas" or "regions" of the body.

    Let's consider if "parts" here means "organs". If so, Sense 6 (component part) might fit.
    But "parts of the body" is a very general term.

    Let's look at the examples for Sense 2: "the farming regions of France; religions in all parts of the world".
    This matches the usage "parts of the body" (meaning regions of the body).

    Let's check Sense 5: "the written part of the exam; the finance section of the company".
    These are more like divisions of a whole.

    Sense 2 seems the most appropriate for "parts of the body" in the context of spatial spread (metastasis).

    Wait, let me re-evaluate Sense 7 one more time. "a portion of a natural object".
    If I say "a part of the tree", is that Sense 2 or Sense 7?
    If I say "a part of the body", is it Sense 2 or Sense 7?
    Sense 2 is "extended spatial location".
    Sense 7 is "a portion of a natural object".

    Actually, looking at WordNet (the actual database), "part" as in "parts of the body" is often mapped to the sense of "region" or "portion of a natural object".

    Let's look at the synonyms again.
    Sense 2: region.
    Sense 7: piece.

    "Other regions of the body" vs "Other pieces of the body".
    "Regions" is much better.

    Therefore, Sense 2 is the strongest candidate.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
2. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
3. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
4. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
5. sense_key=body%1:07:01:: | definition=the main mass of a thing
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
8. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
9. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted
10. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
11. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 11}
```

content:
```json
{"sense_index": 11}
```

reasoning_content:
*   Target lemma: "body"
    *   Target surface form: "body"
    *   Context: "...malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>)..."
    *   The context is medical, discussing cancer (pleural mesothelioma, non-small cell lung cancer) and its spread (metastasis) to other parts of the human body.

    *   1: dead animal or person (corpse) - No.
    *   2: resonating chamber in a musical instrument - No.
    *   3: central message of a communication - No.
    *   4: property of holding together (consistency) - No.
    *   5: main mass of a thing - No.
    *   6: collection of particulars (system) - No.
    *   7: group of persons (entity) - No.
    *   8: 3-dimensional object with mass (astronomy/physics) - No.
    *   9: external structure of a vehicle - No.
    *   10: body excluding head, neck, and limbs (torso) - No.
    *   11: the entire structure of an organism (animal, plant, or human being) - Yes.

    *   The sentence refers to cancer spreading to other parts of the human body. This fits perfectly with sense 11: "the entire structure of an organism (an animal, plant, or human being)".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role
2. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical description of the drug Alimta, mentioning its use in "patients who have not received chemotherapy" and "patients who have not been treated before".
    *   Candidate senses:
        1.  `patient%1:10:00::`: Semantic role (linguistics).
        2.  `patient%1:18:00::`: A person who requires medical care.

    *   The context is clearly medical, discussing a drug (Alimta), cancer treatments (chemotherapy, cisplatin), and the people receiving these treatments.
    *   "patients who have not received chemotherapy" refers to people receiving medical treatment.

    *   Sense 1 is a linguistic term (semantic role).
    *   Sense 2 is a medical term (person receiving care).

    *   Sense 2 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicines
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicines`
    *   Context: "...patients who have not received chemotherapy (<t>medicines</t> for cancer) before..."
    *   Candidate senses:
        1.  `medicine%1:04:00::`: The learned profession (medical school, practice of medicine).
        2.  `medicine%1:06:00::`: Something that treats or prevents or alleviates symptoms (medication, medicinal drug).
        3.  `medicine%1:09:00::`: Branches of medical science (medical specialty).
        4.  `medicine%1:04:02::`: Punishment for one's actions (take your medicine).

    *   The sentence says "chemotherapy (medicines for cancer)".
    *   Chemotherapy consists of drugs/medications used to treat cancer.
    *   This clearly refers to the substance used for treatment, not the profession, the specialty, or a punishment.

    *   Sense 2: "something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug". This fits perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
2. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
5. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: A medical description of the drug Alimta, used to treat "two types of cancer: pleural mesothelioma", "anticancer medicine", "malignant", "chemotherapy (medicines for <t>cancer</t>)".
    *   Candidate senses:
        1.  Zodiac sign (June 21 to July 22).
        2.  Genus of crabs (Cancridae).
        3.  Zodiacal constellation.
        4.  Malignant growth/tumor caused by abnormal cell division.
        5.  Person born under the sign of Cancer.

    *   The context is clearly medical, discussing a drug (Alimta), chemotherapy, malignant growths, and lung cancer.
    *   Sense 4 ("any malignant growth or tumor caused by abnormal and uncontrolled cell division") fits perfectly.

    *   Sense 1: Astrology (Incorrect)
    *   Sense 2: Biology/Crabs (Incorrect)
    *   Sense 3: Astronomy (Incorrect)
    *   Sense 4: Medicine/Oncology (Correct)
    *   Sense 5: Astrology (Incorrect)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: advanced
Target surface form: advanced
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=advanced%5:00:00:late:00 | definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
2. sense_key=advanced%5:00:00:progressive:01 | definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
3. sense_key=advanced%5:00:02:high:02 | definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
4. sense_key=advanced%5:00:00:front:00 | definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies
5. sense_key=advanced%5:00:00:civilized:00 | definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
6. sense_key=advanced%5:00:00:high-tech:00 | definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
7. sense_key=advanced%5:00:00:late:02 | definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
8. sense_key=advanced%5:00:00:precocious:00 | definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 7}
```

content:
```json
{"sense_index": 7}
```

reasoning_content:
*   Target lemma: `advanced`
    *   Target surface form: `advanced`
    *   Context: "...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells."
    *   Key phrase: "advanced or metastatic non-small cell lung cancer"

    *   Sense 1: `far along in time` (e.g., advanced age) - Not applicable.
    *   Sense 2: `ahead of the times` (e.g., advanced teaching methods) - Not applicable.
    *   Sense 3: `at a higher level in training or knowledge or skill` (e.g., advanced degree) - Not applicable.
    *   Sense 4: `situated ahead or going before` (e.g., advance party) - Not applicable.
    *   Sense 5: `(of societies) highly developed` (e.g., advanced societies) - Not applicable.
    *   Sense 6: `ahead in development; complex or intricate` (e.g., advanced technology) - Not applicable.
    *   Sense 7: `comparatively late in a course of development` (e.g., the illness had reached an advanced stage) - This fits perfectly. "Advanced cancer" refers to cancer that has progressed to a later stage.
    *   Sense 8: `farther along in physical or mental development` (e.g., precocious child) - Not applicable.

    *   The context describes a medical condition (non-small cell lung cancer).
    *   "Advanced" is paired with "metastatic," both describing the stage/progression of the disease.
    *   Sense 7 specifically mentions "the illness had reached an advanced stage."

    *   Sense 7 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell
5. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 7}
```

reasoning_content:
*   Target lemma: "cell"
    *   Target surface form: "cell"
    *   Context: A medical description of the drug Alimta, used to treat "non-small cell lung cancer that is not affecting the squamous cells."
    *   Candidate senses:
        1.  Small compartment (honeycomb).
        2.  Mobile phone.
        3.  Electric cell (battery).
        4.  Prison cell.
        5.  Political unit (cadre).
        6.  Monk/nun's room.
        7.  (Biology) basic structural and functional unit of all organisms.

    *   The context mentions "non-small cell lung cancer" and "squamous cells."
    *   This is clearly a biological/medical context referring to the cells of the human body.

    *   Sense 7: "(biology) the basic structural and functional unit of all organisms..." matches perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
2. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
3. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 5}
```

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `affect`
    *   Target surface form: `affecting`
    *   Context: "...advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells."
    *   Meaning: The cancer is not impacting or involving the squamous cells.

    *   Sense 1: `connect closely and often incriminatingly` (involve, regard). Example: "This new ruling affects your business." (More about legal/formal involvement).
    *   Sense 2: `have an effect upon` (impact, bear upon). Example: "Will the new rules affect me?" (General influence).
    *   Sense 3: `have an emotional or cognitive impact upon` (impress, move, strike). Example: "This child impressed me as unusually mature." (Emotional).
    *   Sense 4: `make believe with the intent to deceive` (feign, sham). Example: "He feigned that he was ill." (Pretending).
    *   Sense 5: `act physically on; have an effect upon`. Example: "the medicine affects my heart rate." (Physical/biological effect).

    *   The context is medical: "non-small cell lung cancer that is not affecting the squamous cells."
    *   This describes a physical/biological process where the disease (cancer) is not acting upon or impacting a specific type of cell (squamous cells).
    *   Sense 5 specifically mentions "act physically on; have an effect upon" and gives a medical example ("the medicine affects my heart rate").
    *   Sense 2 is a general "have an effect upon," but Sense 5 is more specific to physical/biological action.

    *   Sense 2: General effect.
    *   Sense 5: Physical/biological effect.
    *   In medical contexts, when a disease "affects" an organ or cell, it is acting physically on it. Sense 5 is the most precise fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
2. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
5. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
6. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before..."
    *   Meaning: The medicine (Alimta) is employed or utilized for a specific medical purpose (treating cancer).

    *   Sense 1: `take or consume (regularly or habitually)` (e.g., "She uses drugs rarely"). This refers to the *person* using the substance, not the substance being used.
    *   Sense 2: `habitually do something (use only in the past tense)` (e.g., "She used to call her mother"). This is the auxiliary "used to". Not applicable here.
    *   Sense 3: `use up, consume fully` (e.g., "expended its time"). Not applicable here.
    *   Sense 4: `avail oneself to` (e.g., "apply a principle"). Not applicable here.
    *   Sense 5: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (e.g., "use your head!", "utilize, utilise, apply, employ"). This fits perfectly. The medicine is employed for the purpose of treating cancer.
    *   Sense 6: `seek or achieve an end by using to one's advantage` (e.g., "uses her influential friends"). This implies manipulation or strategic advantage. Not applicable here.

    *   The sentence "Alimta is used in combination with cisplatin..." means Alimta is *employed* or *utilized* as a treatment. This aligns exactly with Sense 5.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text describing the use of the drug Alimta for treating cancer. The specific sentence is: "Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before..."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The context is clearly medical ("Alimta", "solution for infusion", "cancer", "chemotherapy", "cisplatin").
    *   The word "patients" refers to the people receiving the treatment.

    *   Sense 1: "a person who requires medical care" - This fits perfectly.
    *   Sense 2: "the semantic role of an entity..." - This is a linguistic term (patient role in grammar), which is completely irrelevant to the medical context.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treated
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke
2. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
3. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
4. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
5. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `treat`
    *   Target surface form: `treated`
    *   Context: "Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before..."
    *   General context: Medical information about a drug (Alimta) used for cancer.

    *   Sense 1: regard or consider in a specific way (e.g., "treated his advances as a joke").
    *   Sense 2: provide treatment for (e.g., "The doctor treated my broken leg").
    *   Sense 3: act on verbally or in some form of artistic expression (e.g., "This book deals with incest").
    *   Sense 4: provide with a gift or entertainment (e.g., "treated us to the circus").
    *   Sense 5: interact in a certain way (e.g., "Treat him with caution").
    *   Sense 6: provide with choice or abundant food or drink (e.g., "treating her houseguests with good food").
    *   Sense 7: engage in negotiations (e.g., "treat with the King").
    *   Sense 8: subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition (e.g., "process cheese").

    *   The sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before..."
    *   In this medical context, "treated" refers to receiving medical care or medication for a disease (cancer).
    *   Sense 2 ("provide treatment for") fits perfectly.
    *   Sense 8 ("subject to a process or treatment") is more about industrial or chemical processing (like "process cheese") or general remedying, but Sense 2 is the specific medical sense ("care for").

    *   Sense 2: "provide treatment for" / "care for". Example: "The doctor treated my broken leg". This matches the medical context of patients receiving cancer treatment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text describing the use of the drug Alimta for treating cancer. The specific sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The word "patients" refers to people receiving treatment (chemotherapy) for cancer.
    *   This clearly aligns with the definition "a person who requires medical care."
    *   It does not refer to a linguistic/semantic role (the "patient" role in grammar).

    *   Sense 1: Medical patient. (Correct)
    *   Sense 2: Linguistic patient role. (Incorrect)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
2. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
3. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
4. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
5. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up
6. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "type"
    *   Target surface form: "type"
    *   Context: "...and on its own in patients who have received another <t>type</t> of chemotherapy in the past."
    *   Candidate senses:
        1.  `type%1:10:00::`: all of the tokens of the same symbol (characters)
        2.  `type%1:09:00::`: a subdivision of a particular kind of thing (category/kind)
        3.  `type%1:10:01::`: printed characters
        4.  `type%1:18:00::`: a person of a specified kind (eccentric)
        5.  `type%1:06:00::`: a small metal block (printing)
        6.  `type%1:14:01::`: (biology) taxonomic group

    *   The sentence is: "...and on its own in patients who have received another type of chemotherapy in the past."
    *   Here, "type of chemotherapy" refers to a kind or category of chemotherapy treatment.

    *   Sense 1: Tokens of the same symbol (Incorrect)
    *   Sense 2: A subdivision of a particular kind of thing (Correct - "type of chemotherapy" = "kind of chemotherapy")
    *   Sense 3: Printed characters (Incorrect)
    *   Sense 4: A person of a specified kind (Incorrect)
    *   Sense 5: Metal block for printing (Incorrect)
    *   Sense 6: Taxonomic group (Incorrect - while chemotherapy is medical, this is not a biological taxonomic group like species or genus).

    *   Sense 2 fits perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense
2. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
3. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `past`
    *   Target surface form: `past`
    *   Context: "...and on its own in patients who have received another type of chemotherapy in the <t>past</t>."
    *   Candidate senses:
        1.  `past%1:10:00::`: a verb tense that expresses actions or states in the past (past tense).
        2.  `past%1:28:00::`: the time that has elapsed (past times, yesteryear).
        3.  `past%1:28:01::`: an earlier period in someone's life (especially one that they have reason to keep secret).

    *   The sentence is: "...patients who have received another type of chemotherapy in the past."
    *   "In the past" here refers to a time before the current treatment, a period of time that has already happened.

    *   Sense 1: Verb tense. (Incorrect. This is not about grammar.)
    *   Sense 2: The time that has elapsed. (Fits. "In the past" refers to the time before now.)
    *   Sense 3: An earlier period in someone's life (often secret). (Incorrect. While it is an earlier period in the patient's life, there is no implication of secrecy, and it's a general reference to previous time rather than a specific "personal history" in the biographical/secretive sense.)

    *   Sense 2 is the general term for time gone by. "In the past" is a common idiom meaning "at some time in the past."

    *   Sense 2: "the time that has elapsed" / "past times".
    *   Sense 3: "a earlier period in someone's life (especially one that they have reason to keep secret)".
    *   The context "received another type of chemotherapy in the past" is a medical history, not a "secret past" or a biographical "past" in the sense of a person's life story/secrets. It simply means "previously".

    *   Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
3. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine
4. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: "medicine"
    *   Target surface form: "medicine"
    *   Context: "The <t>medicine</t> can only be obtained with a prescription."
    *   Surrounding context: The text discusses "Alimta," "pemetrexed," "cisplatin," "anticancer medicine," and "chemotherapy (medicines for cancer)."

    *   Sense 1: branches of medical science (medical specialty).
    *   Sense 2: the learned profession (practice of medicine).
    *   Sense 3: punishment for one's actions (metaphorical).
    *   Sense 4: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).

    *   The sentence "The medicine can only be obtained with a prescription" refers to Alimta, which is a drug used to treat cancer.
    *   This fits perfectly with Sense 4 (medication, medicinal drug).

    *   Sense 1: No, it's not a branch of science.
    *   Sense 2: No, it's not a profession.
    *   Sense 3: No, it's not a punishment.
    *   Sense 4: Yes, it's a drug/medication.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
2. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
3. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
6. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
7. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: "only"
    *   Target surface form: "only"
    *   Context: "The medicine can <t>only</t> be obtained with a prescription."

    *   Sense 1: `never except when` (only if, only when). Example: "call me only if your cold gets worse".
    *   Sense 2: `except that`. Example: "It was the same story; only this time she came out better".
    *   Sense 3: `as recently as`. Example: "I spoke to him only an hour ago".
    *   Sense 4: `in the final outcome`. Example: "These news will only make you more upset".
    *   Sense 5: `without any others being included or involved` (entirely, exclusively, solely, alone). Example: "was entirely to blame".
    *   Sense 6: `and nothing more` (merely, simply, just, but). Example: "I was merely asking".
    *   Sense 7: `with nevertheless the final result`. Example: "He arrived only to find his wife dead".

    *   "The medicine can only be obtained with a prescription."
    *   This means the *only* way to get the medicine is with a prescription.
    *   It implies exclusivity: no other way exists.
    *   Let's test the synonyms/definitions:
        *   Sense 1: "The medicine can [never except when] be obtained with a prescription." (A bit clunky, but fits the logic of "only if").
        *   Sense 5: "The medicine can [exclusively/solely] be obtained with a prescription." (Fits very well).
        *   Sense 6: "The medicine can [merely/simply] be obtained with a prescription." (Doesn't fit the meaning of restriction/requirement).

    *   Sense 1 (`never except when`) is often used as a conjunction or adverbial modifier for a condition.
    *   Sense 5 (`without any others being included or involved`) refers to exclusivity.
    *   In "can only be obtained with a prescription", "only" modifies the condition "with a prescription".
    *   Wait, let's look at Sense 1 again: "never except when". "The medicine can [never except when] be obtained with a prescription" doesn't quite work grammatically.
    *   Let's look at Sense 5: "without any others being included or involved". "The medicine can [exclusively] be obtained with a prescription." This fits.
    *   Let's look at Sense 6: "and nothing more". "The medicine can [just] be obtained with a prescription." (Doesn't fit).

    *   "The medicine can only be obtained with a prescription."
    *   This is a restrictive use.
    *   Compare: "You can only enter if you have a ticket." (Sense 1: only if).
    *   Compare: "This is only for adults." (Sense 5: exclusively).
    *   In the target sentence, "only" is an adverb modifying the verb phrase "be obtained with a prescription".
    *   If we replace "only" with "solely" or "exclusively", it makes perfect sense: "The medicine can solely be obtained with a prescription."
    *   If we replace "only" with "never except when", it doesn't fit the syntax.

    *   Sense 5: `without any others being included or involved` (synonyms: entirely, exclusively, solely, alone).
    *   This matches the meaning of "exclusively" or "solely" in the context of the prescription requirement.

    *   Sense 1: "call me only if your cold gets worse" -> "only" modifies the "if" clause.
    *   Target: "can only be obtained with a prescription" -> "only" modifies the condition "with a prescription".
    *   Actually, "only" in "can only be obtained with a prescription" is very similar to "can be obtained only with a prescription".
    *   Is it "exclusively" (Sense 5) or "never except when" (Sense 1)?
    *   "The medicine can be obtained only if you have a prescription." (Sense 1).
    *   "The medicine can only be obtained with a prescription."
    *   Let's check Sense 5 again: "without any others being included or involved".
    *   If we say "The medicine is only for cancer", that's Sense 5.
    *   If we say "The medicine can only be obtained with a prescription", we are saying that the *only* method of obtaining it is with a prescription.
    *   Let's re-evaluate Sense 1: "never except when". "The medicine can [never except when] be obtained with a prescription" is still grammatically awkward.
    *   Let's re-evaluate Sense 5: "The medicine can [exclusively] be obtained with a prescription." This is a strong fit.

    *   Sense 1: `only if`, `only when`.
    *   Sense 5: `entirely`, `exclusively`, `solely`, `alone`.
    *   "The medicine can [solely/exclusively] be obtained with a prescription." (Sense 5).
    *   "The medicine can be obtained [only if] you have a prescription." (Sense 1).
    *   The target sentence is "can only be obtained with a prescription". This is an adverbial use of "only".
    *   In many dictionaries, "only" as an adverb meaning "solely" or "exclusively" is a single sense.
    *   Looking at the provided WordNet senses:
        *   Sense 5: without any others being included or involved (exclusively, solely).
        *   Sense 1: never except when (only if, only when).
    *   The target sentence "can only be obtained with a prescription" means that no other way exists. This is the definition of "exclusively" or "solely".

    *   Sense 1: "call me only if your cold gets worse" (only + if-clause).
    *   Target: "can only be obtained with a prescription" (only + verb phrase + prepositional phrase).
    *   The target sentence doesn't have "if" or "when". It uses "with a prescription".
    *   Therefore, Sense 5 ("exclusively") is a better fit than Sense 1 ("only if").


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: obtain
Target surface form: obtained
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds
2. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
3. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `obtain`
    *   Target surface form: `obtained`
    *   Context: "The medicine can only be <t>obtained</t> with a prescription."
    *   Candidate senses:
        1.  `obtain%2:42:00::` (be valid, applicable, or true)
        2.  `obtain%2:40:00::` (come into possession of)
        3.  `obtain%2:30:00::` (receive a specified treatment (abstract))

    *   The sentence is: "The medicine can only be obtained with a prescription."
    *   In this context, "obtained" means that a person can get or acquire the medicine if they have a prescription.

    *   Sense 1: "be valid, applicable, or true" (e.g., "This theory still holds"). This does not fit.
    *   Sense 2: "come into possession of" (e.g., "How did you obtain the visa?"). This fits perfectly. Getting a medicine is coming into possession of it.
    *   Sense 3: "receive a specified treatment (abstract)" (e.g., "His movie received a good review"). This is about receiving an abstract treatment or reaction, not a physical object like medicine.

    *   Sense 2 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prescription
Target surface form: prescription
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
3. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient
4. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `prescription`
    *   Target surface form: `prescription`
    *   Context: "The medicine can only be obtained with a <t>prescription</t>."
    *   Candidate senses:
        1.  `prescription%1:10:00::`: directions prescribed beforehand; authoritative rules.
        2.  `prescription%1:10:02::`: written instructions for an optician (glasses).
        3.  `prescription%1:10:01::`: written instructions from a physician/dentist to a druggist (the piece of paper/order).
        4.  `prescription%1:06:00::`: a drug that is available only with written instructions (the medicine itself).

    *   The sentence is: "The medicine can only be obtained with a prescription."
    *   Here, "prescription" refers to the *document* or *authorization* required to get the medicine, not the medicine itself.
    *   If it meant the medicine, it would be "The medicine is a prescription."
    *   "Obtained with a [document/authorization]" fits sense 3.

    *   Sense 1: General rules/directions (Incorrect).
    *   Sense 2: Optician/lenses (Incorrect).
    *   Sense 3: Written instructions from a physician to a druggist (Correct).
    *   Sense 4: A drug available only with instructions (Incorrect - the sentence says "The medicine can only be obtained with a prescription", meaning the medicine is obtained *by using* the prescription).

    *   Sense 3 is the most accurate description of the authorization needed to obtain a medicine.