[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: read
Target surface form: read
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, <t>read</t> the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=read%2:31:00:: | definition=interpret something that is written or printed | examples=read the advertisement; Have you read Salman Rushdie?
2. sense_key=read%2:42:00:: | definition=have or contain a certain wording or form | synonyms=say | examples=The passage reads as follows; What does the law say?
3. sense_key=read%2:31:01:: | definition=look at, interpret, and say out loud something that is written or printed | examples=The King will read the proclamation at noon
4. sense_key=read%2:31:06:: | definition=obtain data from magnetic tapes | synonyms=scan | examples=This dictionary can be read by the computer
5. sense_key=read%2:31:02:: | definition=interpret the significance of, as of palms, tea leaves, intestines, the sky; also of human behavior | examples=She read the sky and predicted rain; I can't read his strange behavior
6. sense_key=read%2:31:09:: | definition=interpret something in a certain way; convey a particular meaning or impression | synonyms=take | examples=I read this address as a satire; How should I take this message?
7. sense_key=read%2:31:05:: | definition=be a student of a certain subject | synonyms=learn, study, take | examples=She is reading for the bar exam
8. sense_key=read%2:32:02:: | definition=indicate a certain reading; of gauges and instruments | synonyms=register, show, record | examples=The thermometer showed thirteen degrees below zero; The gauge read `empty'
9. sense_key=read%2:36:05:: | definition=audition for a stage role by reading parts of a role | examples=He is auditioning for `Julius Caesar' at Stratford this year
10. sense_key=read%2:31:08:: | definition=to hear and understand | examples=I read you loud and clear!
11. sense_key=read%2:31:04:: | definition=make sense of a language | synonyms=understand, interpret, translate | examples=She understands French; Can you read Greek?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `read`
    *   Target surface form: `read`
    *   Context: "If you want more information on the basis of the CHMP recommendations, <t>read</t> the Scientific Discussion (also part of the EPAR)."
    *   Candidate senses:
        1.  `interpret something that is written or printed` (e.g., read the advertisement)
        2.  `have or contain a certain wording or form` (e.g., The passage reads as follows)
        3.  `look at, interpret, and say out loud something that is written or printed` (e.g., read the proclamation)
        4.  `obtain data from magnetic tapes` (e.g., read by the computer)
        5.  `interpret the significance of...` (e.g., read the sky)
        6.  `interpret something in a certain way...` (e.g., read this address as a satire)
        7.  `be a student of a certain subject` (e.g., reading for the bar exam)
        8.  `indicate a certain reading; of gauges and instruments` (e.g., The gauge read 'empty')
        9.  `audition for a stage role...` (e.g., auditioning for 'Julius Caesar')
        10. `to hear and understand` (e.g., I read you loud and clear)
        11. `make sense of a language` (e.g., Can you read Greek?)

    *   The sentence is an instruction to the reader: "If you want more information... read the Scientific Discussion".
    *   The "Scientific Discussion" is a document (part of the EPAR).
    *   The action requested is to process the written information in that document to gain knowledge.

    *   Sense 1: `interpret something that is written or printed`. This fits perfectly. Reading a document to get information.
    *   Sense 2: `have or contain a certain wording`. This is for when the text itself is the subject (e.g., "The sign reads 'Stop'"). Not applicable here.
    *   Sense 3: `look at, interpret, and say out loud`. This is reading aloud. The context doesn't imply reading aloud.
    *   Sense 4: `obtain data from magnetic tapes`. This is for computers. Not applicable.
    *   Sense 5: `interpret the significance of (palms, tea leaves)`. Not applicable.
    *   Sense 6: `interpret something in a certain way`. Not applicable.
    *   Sense 7: `be a student of a certain subject`. Not applicable.
    *   Sense 8: `indicate a certain reading (gauges)`. Not applicable.
    *   Sense 9: `audition for a stage role`. Not applicable.
    *   Sense 10: `to hear and understand`. Not applicable.
    *   Sense 11: `make sense of a language`. Not applicable.

    *   Sense 1 is the most general and accurate description of reading a document for information.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: discussion
Target surface form: Discussion
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific <t>Discussion</t> (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=discussion%1:10:02:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=treatment, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased
2. sense_key=discussion%1:10:00:: | definition=an exchange of views on some topic | synonyms=give-and-take, word | examples=we had a good discussion; we had a word or two about it

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

finish_reason: stop

content:
```json
{"sense_index": 1}
```

role: assistant

reasoning_content:
*   Target lemma: `discussion`
    *   Target surface form: `Discussion`
    *   Context: "If you want more information on the basis of the CHMP recommendations, read the Scientific <t>Discussion</t> (also part of the EPAR)."
    *   Candidate senses:
        1.  `discussion%1:10:02::`: an extended communication (often interactive) dealing with some particular topic (synonyms: treatment, discourse; examples: "the book contains an excellent discussion of modal logic").
        2.  `discussion%1:10:00::`: an exchange of views on some topic (synonyms: give-and-take, word; examples: "we had a good discussion").

    *   The context refers to a "Scientific Discussion" which is a part of a document (the EPAR).
    *   It is something you "read" to get "more information on the basis of the CHMP recommendations."
    *   This implies a written exposition, analysis, or treatment of a subject, rather than a conversation or an exchange of views.

    *   Sense 1: "an extended communication... dealing with some particular topic" (synonyms: treatment, discourse). Example: "the book contains an excellent discussion of modal logic". This fits perfectly with a section of a scientific report.
    *   Sense 2: "an exchange of views on some topic" (synonyms: give-and-take, word). Example: "we had a good discussion". This refers to a conversation/dialogue, which does not fit a written section of a report.

    *   The "Scientific Discussion" is a written treatment of the evidence/basis for recommendations.
    *   Sense 1 is the correct fit.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: part
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also <t>part</t> of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 9}
```

content:
```json
{"sense_index": 9}
```

reasoning_content:
*   Target lemma: `part`
    *   Target surface form: `part`
    *   Context: "If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also <t>part</t> of the EPAR)."
    *   Meaning: The "Scientific Discussion" is a section or a component of the "European Public Assessment Report (EPAR)".

    *   Sense 1: `something determined in relation to something that includes it` (portion, component part, constituent). Example: "feel a part of something bigger".
    *   Sense 2: `something less than the whole of a human artifact` (portion). Example: "rear part of the house".
    *   Sense 3: `a portion of a natural object` (piece). Example: "piece of granite".
    *   Sense 4: `that which concerns a person with regard to a particular role or situation`. Example: "vigilance on our part".
    *   Sense 5: `the extended spatial location of something` (region). Example: "parts of the world".
    *   Sense 6: `the actions and activities assigned to or required or expected of a person or group` (function, office, role). Example: "government must do its part".
    *   Sense 7: `an actor's portrayal of someone in a play` (character, role). Example: "played the part of Desdemona".
    *   Sense 8: `assets belonging to or due to or contributed by an individual person or group` (share, portion). Example: "share in cash".
    *   Sense 9: `one of the portions into which something is regarded as divided and which together constitute a whole` (section, division). Example: "the written part of the exam; the finance section of the company".
    *   Sense 10: `a line of scalp...` (parting).
    *   Sense 11: `the melody carried by a particular voice...` (voice).
    *   Sense 12: `the part played by a person in bringing about a result` (contribution, share).

    *   The "Scientific Discussion" is a document/section within a larger document (the EPAR).
    *   Sense 9 specifically mentions "one of the portions into which something is regarded as divided" and gives the example "the written part of the exam" or "the finance section of the company". This fits perfectly with a section of a report.
    *   Sense 1 is more general ("something determined in relation to something that includes it").
    *   Sense 2 is for "human artifacts" (physical objects like a house). While a document is a human artifact, Sense 9 is more specific to divisions/sections of a whole (like a report).

    *   Sense 9: "one of the portions into which something is regarded as divided and which together constitute a whole" (synonyms: section, division).
    *   Context: "Scientific Discussion (also part of the EPAR)".
    *   The Scientific Discussion is a section/division of the EPAR.

    *   Sense 1: General component.
    *   Sense 9: Section/division of a whole.
    *   In the context of documents (EPAR, Scientific Discussion), "part" usually means a section or division. Sense 9's example "the written part of the exam" is very similar to "the Scientific Discussion part of the EPAR".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: powder
Target surface form: powder
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a <t>powder</t> that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=powder%1:27:00:: | definition=a solid substance in the form of tiny loose particles; a solid that has been pulverized | synonyms=pulverization, pulverisation
2. sense_key=powder%1:27:01:: | definition=a mixture of potassium nitrate, charcoal, and sulfur in a 75:15:10 ratio which is used in gunnery, time fuses, and fireworks | synonyms=gunpowder
3. sense_key=powder%1:06:01:: | definition=any of various cosmetic or medical preparations dispensed in the form of a pulverized powder

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `powder`
    *   Target surface form: `powder`
    *   Context: "Alimta is a <t>powder</t> that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed."
    *   Candidate senses:
        1.  `powder%1:27:00::`: a solid substance in the form of tiny loose particles; a solid that has been pulverized.
        2.  `powder%1:27:01::`: a mixture of potassium nitrate, charcoal, and sulfur... (gunpowder).
        3.  `powder%1:06:01::`: any of various cosmetic or medical preparations dispensed in the form of a pulverized powder.

    *   The context describes "Alimta", which is a medicine (containing pemetrexed) used for infusion.
    *   It is described as a "powder" that is made into a solution.
    *   This is clearly a medical preparation.

    *   Sense 1 is a general definition of powder (tiny loose particles).
    *   Sense 2 is gunpowder.
    *   Sense 3 is specifically for cosmetic or medical preparations dispensed as powder.

    *   While Sense 1 is technically correct (it is a solid substance in the form of tiny particles), Sense 3 is more specific and fits the context of a medicine (Alimta) perfectly. In fine-grained WSD, the most specific correct sense is usually preferred.

    *   Sense 3: "any of various cosmetic or medical preparations dispensed in the form of a pulverized powder".
    *   Context: "Alimta is a powder... It contains the active substance pemetrexed." (Alimta is a medical preparation).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: solution
Target surface form: solution
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a <t>solution</t> for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=solution%1:27:00:: | definition=a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution | examples=he used a solution of peroxide and water
2. sense_key=solution%1:10:00:: | definition=a statement that solves a problem or explains how to solve the problem | synonyms=answer, result, resolution, solvent | examples=they were trying to find a peaceful solution; the answers were in the back of the book
3. sense_key=solution%1:09:00:: | definition=a method for solving a problem | examples=the easy solution is to look it up in the handbook
4. sense_key=solution%1:14:00:: | definition=the set of values that give a true statement when substituted into an equation | synonyms=root
5. sense_key=solution%1:04:00:: | definition=the successful action of solving a problem | examples=the solution took three hours

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "solution"
    *   Target surface form: "solution"
    *   Context: "Alimta is a powder that is made up into a <t>solution</t> for infusion (drip into a vein)."
    *   Candidate senses:
        1.  `solution%1:27:00::`: a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution.
        2.  `solution%1:10:00::`: a statement that solves a problem or explains how to solve the problem.
        3.  `solution%1:09:00::`: a method for solving a problem.
        4.  `solution%1:14:00::`: the set of values that give a true statement when substituted into an equation.
        5.  `solution%1:04:00::`: the successful action of solving a problem.

    *   The context describes a medicine (Alimta) which is a powder that is "made up into a solution for infusion (drip into a vein)".
    *   In a medical/chemical context, a "solution for infusion" refers to a liquid mixture where a solute (the powder) is dissolved in a solvent.

    *   Sense 1: "a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution". This matches the chemical/medical meaning perfectly.
    *   Sense 2: "a statement that solves a problem". Not applicable.
    *   Sense 3: "a method for solving a problem". Not applicable.
    *   Sense 4: "the set of values that give a true statement when substituted into an equation". Not applicable.
    *   Sense 5: "the successful action of solving a problem". Not applicable.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for <t>infusion</t> (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
2. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)
3. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)
4. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "infusion"
    *   Target surface form: "infusion"
    *   Context: "Alimta is a powder that is made up into a solution for <t>infusion</t> (drip into a vein)."
    *   Candidate senses:
        1.  `infusion%1:27:00::`: a solution obtained by steeping or soaking a substance (usually in water) (e.g., tea).
        2.  `infusion%1:22:00::`: the process of extracting certain active properties by steeping or soaking.
        3.  `infusion%1:04:00::`: (medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force).
        4.  `infusion%1:04:01::`: the act of infusing or introducing a certain modifying element or quality (e.g., new talent).

    *   The context explicitly mentions "solution for infusion (drip into a vein)".
    *   This is a medical context involving the administration of a drug (Alimta/pemetrexed) into a vein.

    *   Sense 1: Steeping/soaking (like tea). Not applicable.
    *   Sense 2: Process of extracting properties by steeping. Not applicable.
    *   Sense 3: Medical introduction of a substance into a vein. This matches perfectly ("drip into a vein").
    *   Sense 4: Introducing a quality/element (metaphorical). Not applicable.

    *   The best sense is index 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: drip
Target surface form: drip
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (<t>drip</t> into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=drip%2:38:00:: | definition=fall in drops | examples=Water is dripping from the faucet
2. sense_key=drip%2:35:10:: | definition=let or cause to fall in drops | synonyms=dribble, drop | examples=dribble oil into the mixture

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "drip"
    *   Target surface form: "drip"
    *   Context: "...Alimta is a powder that is made up into a solution for infusion (<t>drip</t> into a vein)."
    *   Candidate senses:
        1.  `drip%2:38:00::` (fall in drops) - Intransitive verb.
        2.  `drip%2:35:10::` (let or cause to fall in drops) - Transitive verb.

    *   The sentence is: "...a solution for infusion (<t>drip</t> into a vein)."
    *   In this context, "drip" is used as a verb describing the action of the solution being administered.
    *   The solution is being "dripped" into a vein.
    *   Is it "falling in drops" (intransitive) or "being let/caused to fall in drops" (transitive/causative)?
    *   The phrase "drip into a vein" implies the action of the medicine entering the vein. While "drip" can be intransitive (the liquid drips), in the context of a medical infusion, it's the process of administering the fluid.
    *   Wait, let's look at the grammar: "solution for infusion (drip into a vein)". This is a parenthetical explanation of "infusion".
    *   "Infusion" is the act of introducing a fluid into the body.
    *   "drip into a vein" -> The solution drips into a vein.
    *   If the solution is the subject, it "falls in drops" (Sense 1).
    *   If the implied actor (the nurse/machine) is the subject, it "lets it fall in drops" (Sense 2).
    *   However, looking at the phrasing "solution for infusion (drip into a vein)", "drip" is likely acting as a shorthand for "which drips into a vein" or "to be dripped into a vein".
    *   If it's "which drips", it's Sense 1.
    *   If it's "to be dripped", it's the passive of Sense 2.
    *   Let's re-evaluate the senses:
        *   Sense 1: "fall in drops" (Intransitive)
        *   Sense 2: "let or cause to fall in drops" (Transitive)
    *   In "drip into a vein", the solution is the thing doing the dripping. "Water is dripping from the faucet" (Sense 1) is very similar to "The solution is dripping into the vein".
    *   Sense 2 requires an object (e.g., "dribble oil into the mixture"). In "drip into a vein", "into a vein" is a prepositional phrase indicating direction, not a direct object.
    *   Therefore, "drip" here is used intransitively.

    *   Sense 1: fall in drops. (Matches "drip into a vein")
    *   Sense 2: let or cause to fall in drops. (Requires an object)

    *   The solution drips (falls in drops) into the vein.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: vein
Target surface form: vein
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a <t>vein</t>). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=vein%1:08:00:: | definition=a blood vessel that carries blood from the capillaries toward the heart | synonyms=vena, venous blood vessel | examples=all veins except the pulmonary vein carry unaerated blood
2. sense_key=vein%1:10:00:: | definition=a distinctive style or manner | examples=he continued in this vein for several minutes
3. sense_key=vein%1:20:00:: | definition=any of the vascular bundles or ribs that form the branching framework of conducting and supporting tissues in a leaf or other plant organ | synonyms=nervure
4. sense_key=vein%1:17:00:: | definition=a layer of ore between layers of rock | synonyms=mineral vein
5. sense_key=vein%1:05:00:: | definition=one of the horny ribs that stiffen and support the wing of an insect | synonyms=nervure

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `vein`
    *   Target surface form: `vein`
    *   Context: "Alimta is a powder that is made up into a solution for infusion (drip into a <t>vein</t>)."
    *   Candidate senses:
        1.  `vein%1:08:00::`: blood vessel carrying blood toward the heart.
        2.  `vein%1:10:00::`: distinctive style or manner.
        3.  `vein%1:20:00::`: vascular bundles in a leaf/plant.
        4.  `vein%1:17:00::`: layer of ore in rock.
        5.  `vein%1:05:00::`: ribs in an insect wing.

    *   The context mentions "solution for infusion (drip into a vein)".
    *   "Infusion" in a medical context refers to the administration of fluids or medication directly into a blood vessel.
    *   "Drip into a vein" clearly refers to the anatomical blood vessel.

    *   Sense 1: Blood vessel (matches perfectly).
    *   Sense 2: Style/manner (does not match).
    *   Sense 3: Plant tissue (does not match).
    *   Sense 4: Mineral ore (does not match).
    *   Sense 5: Insect wing (does not match).

    *   The best sense is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: contain
Target surface form: contains
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It <t>contains</t> the active substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=contain%2:42:00:: | definition=include or contain; have as a component | synonyms=incorporate, comprise | examples=A totally new idea is comprised in this paper; The record contains many old songs from the 1930's
2. sense_key=contain%2:42:13:: | definition=contain or hold; have within | synonyms=hold, bear, carry | examples=The jar carries wine; The canteen holds fresh water
3. sense_key=contain%2:41:00:: | definition=lessen the intensity of; temper; hold in restraint; hold or keep within limits | synonyms=control, hold in, hold, check, curb, moderate | examples=moderate your alcohol intake; hold your tongue
4. sense_key=contain%2:42:06:: | definition=be divisible by | examples=24 contains 6
5. sense_key=contain%2:42:14:: | definition=be capable of holding or containing | synonyms=take, hold | examples=This box won't take all the items; The flask holds one gallon
6. sense_key=contain%2:33:00:: | definition=hold back, as of a danger or an enemy; check the expansion or influence of | synonyms=check, turn back, arrest, stop, hold back | examples=Arrest the downward trend; Check the growth of communism in South East Asia

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `contain`
    *   Target surface form: `contains`
    *   Context: "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It <t>contains</t> the active substance pemetrexed."
    *   Meaning: The medicine (Alimta) has pemetrexed as one of its ingredients/components.

    *   Sense 1: `include or contain; have as a component` (Synonyms: incorporate, comprise). Example: "The record contains many old songs from the 1930's".
    *   Sense 2: `contain or hold; have within` (Synonyms: hold, bear, carry). Example: "The jar carries wine".
    *   Sense 3: `lessen the intensity of; temper; hold in restraint` (Synonyms: control, curb).
    *   Sense 4: `be divisible by`. Example: "24 contains 6".
    *   Sense 5: `be capable of holding or containing` (Capacity). Example: "The flask holds one gallon".
    *   Sense 6: `hold back, as of a danger or an enemy`. Example: "Check the growth of communism".

    *   The context describes a chemical composition (a medicine containing an active substance).
    *   Sense 1 ("have as a component") fits perfectly for ingredients or chemical composition.
    *   Sense 2 ("hold; have within") usually refers to a container holding a substance (like a jar holding wine), whereas Sense 1 refers to the substance itself being composed of something. Alimta *is* the substance/mixture, and pemetrexed is a *component* of it.

    *   Sense 1: "have as a component" -> Alimta has pemetrexed as a component. (Correct)
    *   Sense 2: "contain or hold; have within" -> Alimta holds pemetrexed. (Possible, but Sense 1 is more precise for ingredients).

    *   Sense 1 is the standard sense for "contains [ingredient]".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: active
Target surface form: active
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the <t>active</t> substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=active%3:00:02:: | definition=tending to become more severe or wider in scope | examples=active tuberculosis
2. sense_key=active%5:00:00:operational:00 | definition=engaged in or ready for military or naval operations | synonyms=combat-ready, fighting | examples=on active duty; the platoon is combat-ready
3. sense_key=active%3:00:03:: | definition=disposed to take action or effectuate change | examples=a director who takes an active interest in corporate operations; an active antagonism
4. sense_key=active%5:00:00:involved:00 | definition=taking part in an activity | synonyms=participating | examples=an active member of the club; he was politically active
5. sense_key=active%3:00:01:: | definition=characterized by energetic activity | examples=an active toddler; active as a gazelle
6. sense_key=active%3:00:07:: | definition=exerting influence or producing a change or effect | examples=an active ingredient
7. sense_key=active%3:00:06:: | definition=full of activity or engaged in continuous activity | examples=an active seaport; an active bond market
8. sense_key=active%5:00:00:existent:00 | definition=in operation | synonyms=alive | examples=keep hope alive; the tradition was still alive
9. sense_key=active%3:00:10:: | definition=(of the sun) characterized by an increased occurrence of sunspots and flares and radio emissions
10. sense_key=active%3:00:09:: | definition=expressing that the subject of the sentence has the semantic function of actor: | examples=Hemingway favors active constructions
11. sense_key=active%3:00:00:: | definition=(used of verbs (e.g. `to run') and participial adjectives (e.g. `running' in `running water')) expressing action rather than a state of being | synonyms=dynamic
12. sense_key=active%3:00:05:: | definition=(of e.g. volcanos) capable of erupting
13. sense_key=active%3:00:04:: | definition=(of e.g. volcanos) erupting or liable to erupt | examples=active volcanos
14. sense_key=active%3:00:08:: | definition=engaged in full-time work | examples=active duty; though past retirement age he is still active in his profession

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: `active`
    *   Target surface form: `active`
    *   Context: "It contains the <t>active</t> substance pemetrexed."
    *   Domain: Medical/Pharmaceutical (EPAR, medicine, substance).

    *   1: tending to become more severe or wider in scope (e.g., active tuberculosis) - *Incorrect.*
    *   2: engaged in or ready for military or naval operations (e.g., active duty) - *Incorrect.*
    *   3: disposed to take action or effectuate change (e.g., active interest) - *Incorrect.*
    *   4: taking part in an activity (e.g., active member) - *Incorrect.*
    *   5: characterized by energetic activity (e.g., active toddler) - *Incorrect.*
    *   6: exerting influence or producing a change or effect (e.g., an active ingredient) - *Matches perfectly.*
    *   7: full of activity or engaged in continuous activity (e.g., active seaport) - *Incorrect.*
    *   8: in operation (e.g., keep hope alive) - *Incorrect.*
    *   9: (of the sun) characterized by sunspots - *Incorrect.*
    *   10: expressing that the subject is the actor (grammar) - *Incorrect.*
    *   11: expressing action rather than state (grammar) - *Incorrect.*
    *   12: (of volcanoes) capable of erupting - *Incorrect.*
    *   13: (of volcanoes) erupting - *Incorrect.*
    *   14: engaged in full-time work - *Incorrect.*

    *   The context "active substance pemetrexed" refers to the pharmaceutical component that produces the therapeutic effect.
    *   Sense 6: "exerting influence or producing a change or effect" with the example "an active ingredient".
    *   "Active substance" is a synonym for "active ingredient" in pharmaceutical contexts.

    *   Sense index: 6.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: substance
Target surface form: substance
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active <t>substance</t> pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=substance%1:03:00:: | definition=the real physical matter of which a person or thing consists | examples=DNA is the substance of our genes
2. sense_key=substance%1:09:01:: | definition=the choicest or most essential or most vital part of some idea or experience | synonyms=kernel, core, center, centre, essence, gist | examples=the gist of the prosecutor's argument; the heart and soul of the Republican Party
3. sense_key=substance%1:09:00:: | definition=the idea that is intended | synonyms=meaning | examples=What is the meaning of this proverb?
4. sense_key=substance%1:27:00:: | definition=material of a particular kind or constitution | examples=the immune response recognizes invading substances
5. sense_key=substance%1:21:00:: | definition=considerable capital (wealth or income) | synonyms=means | examples=he is a man of means
6. sense_key=substance%1:10:00:: | definition=what a communication that is about something is about | synonyms=message, content, subject matter
7. sense_key=substance%1:03:01:: | definition=a particular kind or species of matter with uniform properties | examples=shigella is one of the most toxic substances known to man

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 7}
```

content:
```json
{"sense_index": 7}
```

reasoning_content:
*   Target lemma: `substance`
    *   Target surface form: `substance`
    *   Context: "It contains the active <t>substance</t> pemetrexed."
    *   Domain: Medical/Pharmaceutical (EPAR, CHMP, medicine, solution for infusion).

    *   Sense 1: `substance%1:03:00::` - the real physical matter of which a person or thing consists (e.g., DNA is the substance of our genes).
    *   Sense 2: `substance%1:09:01::` - the choicest or most essential or most vital part of some idea or experience (kernel, core, essence).
    *   Sense 3: `substance%1:09:00::` - the idea that is intended (meaning).
    *   Sense 4: `substance%1:27:00::` - material of a particular kind or constitution (e.g., immune response recognizes invading substances).
    *   Sense 5: `substance%1:21:00::` - considerable capital (wealth or income).
    *   Sense 6: `substance%1:10:00::` - what a communication is about (message, content).
    *   Sense 7: `substance%1:03:01::` - a particular kind or species of matter with uniform properties (e.g., shigella is one of the most toxic substances known to man).

    *   The context is "active substance pemetrexed".
    *   "Pemetrexed" is a chemical compound/drug.
    *   "Active substance" (or active pharmaceutical ingredient) refers to a specific chemical entity with uniform properties that produces the intended pharmacological effect.

    *   Sense 4 (`material of a particular kind or constitution`) and Sense 7 (`a particular kind or species of matter with uniform properties`) are the closest.
    *   Sense 4 is more general ("material of a particular kind").
    *   Sense 7 is more specific to chemistry/science ("particular kind or species of matter with uniform properties").
    *   Looking at the example for Sense 7: "shigella is one of the most toxic substances known to man". This fits the description of a chemical/biological agent like pemetrexed.
    *   Looking at the example for Sense 4: "the immune response recognizes invading substances". This is also close, but Sense 7's definition of "uniform properties" aligns better with the definition of a chemical substance in a pharmaceutical context.

    *   Sense 7: "a particular kind or species of matter with uniform properties". This is the standard definition of a chemical substance.
    *   Sense 4: "material of a particular kind or constitution". This is slightly broader.
    *   In pharmaceutical terminology, "active substance" refers to the specific chemical compound. Sense 7 is the most precise fit for a chemical compound.

    *   Sense 1: Physical matter of which something consists (too general).
    *   Sense 2: Essence of an idea (metaphorical).
    *   Sense 3: Meaning (metaphorical).
    *   Sense 5: Wealth (irrelevant).
    *   Sense 6: Content of communication (irrelevant).

    *   Sense 7 is the best fit for a chemical/pharmaceutical agent.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta <t>used</t> for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos).

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "What is Alimta <t>used</t> for? Alimta is used to treat two types of cancer..."
    *   Meaning: The drug Alimta is employed or utilized for the purpose of treating cancer.

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (Synonyms: utilize, utilise, apply, employ).
    *   Sense 2: `take or consume (regularly or habitually)` (Synonyms: habituate).
    *   Sense 3: `use up, consume fully` (Synonyms: expend).
    *   Sense 4: `seek or achieve an end by using to one's advantage`.
    *   Sense 5: `avail oneself to` (Synonyms: practice, apply).
    *   Sense 6: `habitually do something (use only in the past tense)`.

    *   The context "What is Alimta used for?" and "Alimta is used to treat..." clearly refers to the purpose or application of the drug.
    *   Sense 1 ("employ for a particular purpose") fits perfectly.
    *   Sense 2 (consume drugs) refers to the *act* of taking a drug, but "used for [purpose]" refers to the *application* of the drug.
    *   Sense 3 (use up) is incorrect.
    *   Sense 4 (using to one's advantage) is incorrect.
    *   Sense 5 (practice a religion/principle) is incorrect.
    *   Sense 6 (past habit) is incorrect.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is <t>used</t> to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "What is Alimta used for? Alimta is <t>used</t> to treat two types of cancer..."
    *   Meaning: Alimta (a medicine) is employed or utilized for the purpose of treating cancer.

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (Synonyms: utilize, utilise, apply, employ).
    *   Sense 2: `take or consume (regularly or habitually)` (Synonyms: habituate).
    *   Sense 3: `use up, consume fully` (Synonyms: expend).
    *   Sense 4: `seek or achieve an end by using to one's advantage`.
    *   Sense 5: `avail oneself to` (Synonyms: practice, apply).
    *   Sense 6: `habitually do something (use only in the past tense)`.

    *   The context "Alimta is used to treat two types of cancer" means the drug is employed for a specific medical purpose.
    *   Sense 1 fits perfectly: "employ for a particular purpose".
    *   Sense 2 refers to consumption (like drugs as an addiction or habit), which isn't the primary meaning here (though it's a drug, the sentence is about its medical application/purpose).
    *   Sense 3 refers to consuming something until it's gone.
    *   Sense 4 refers to manipulating someone or something for advantage.
    *   Sense 5 refers to practicing a religion or applying a principle.
    *   Sense 6 refers to a past habit ("I used to...").

    *   The target word "used" in "Alimta is used to treat..." is the passive form of "use" (Sense 1).

    *   Sense 1: `put into service; make work or employ for a particular purpose` -> Matches.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treat
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to <t>treat</t> two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "treat"
    *   Target surface form: "treat"
    *   Context: "Alimta is used to <t>treat</t> two types of cancer..."
    *   Meaning: In this context, "treat" refers to providing medical care or treatment for a disease (cancer).

    *   Sense 1: interact in a certain way (handle, do by) - *Incorrect*
    *   Sense 2: subject to a process or treatment (process cheese, process hair) - *Incorrect (this is more about industrial/chemical processing)*
    *   Sense 3: provide treatment for (care for, doctor treated my broken leg) - *Correct (medical treatment)*
    *   Sense 4: act on verbally or in some form of artistic expression (cover, handle) - *Incorrect*
    *   Sense 5: provide with a gift or entertainment - *Incorrect*
    *   Sense 6: provide with choice or abundant food or drink - *Incorrect*
    *   Sense 7: engage in negotiations - *Incorrect*
    *   Sense 8: regard or consider in a specific way - *Incorrect*

    *   The context is medical ("Alimta is used to treat two types of cancer").
    *   Sense 3 specifically mentions "provide treatment for" and gives the example "The doctor treated my broken leg". This fits perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: types
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two <t>types</t> of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `type`
    *   Target surface form: `types`
    *   Context: "Alimta is used to treat two <t>types</t> of cancer: pleural mesothelioma..."
    *   Candidate senses:
        1.  `type%1:09:00::`: a subdivision of a particular kind of thing (Example: "what type of sculpture do you prefer?")
        2.  `type%1:18:00::`: a person of a specified kind (usually with many eccentricities)
        3.  `type%1:14:01::`: (biology) the taxonomic group whose characteristics are used to define the next higher taxon
        4.  `type%1:10:01::`: printed characters
        5.  `type%1:10:00::`: all of the tokens of the same symbol
        6.  `type%1:06:00::`: a small metal block bearing a raised character...

    *   The sentence says "two types of cancer".
    *   Cancer is a general category, and "pleural mesothelioma" and "non-small cell lung cancer" are specific kinds or subdivisions of cancer.
    *   This matches sense 1: "a subdivision of a particular kind of thing".

    *   Sense 1: "a subdivision of a particular kind of thing" - Fits perfectly.
    *   Sense 2: "a person of a specified kind" - Not a person.
    *   Sense 3: "(biology) the taxonomic group..." - This is a very specific biological/taxonomic definition (type specimen/group), not the general meaning of "kind of disease".
    *   Sense 4: "printed characters" - Not related to printing.
    *   Sense 5: "all of the tokens of the same symbol" - Not related to symbols.
    *   Sense 6: "a small metal block..." - Not related to printing blocks.

    *   The best fit is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of <t>cancer</t>: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: "Alimta is used to treat two types of <t>cancer</t>: pleural mesothelioma (cancer of the lining of the lungs...)"
    *   Candidate senses:
        1.  `cancer%1:26:00::`: malignant growth or tumor caused by abnormal and uncontrolled cell division.
        2.  `cancer%1:18:00::`: (astrology) person born while the sun is in Cancer.
        3.  `cancer%1:17:00::`: zodiacal constellation.
        4.  `cancer%1:15:00::`: fourth sign of the zodiac.
        5.  `cancer%1:05:00::`: type genus of the family Cancridae.

    *   The context discusses "Alimta", a "solution for infusion", "active substance pemetrexed", "treat two types of cancer", "pleural mesothelioma", "anticancer medicine", "chemotherapy", and "non-small cell lung cancer".
    *   This is clearly medical context referring to the disease.

    *   Sense 1: "any malignant growth or tumor caused by abnormal and uncontrolled cell division" - Matches perfectly.
    *   Sense 2: Astrology (person) - Incorrect.
    *   Sense 3: Constellation - Incorrect.
    *   Sense 4: Zodiac sign - Incorrect.
    *   Sense 5: Genus of crabs - Incorrect.

    *   The best sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (<t>cancer</t> of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "cancer"
    *   Target surface form: "cancer"
    *   Context: "Alimta is used to treat two types of cancer: pleural mesothelioma (<t>cancer</t> of the lining of the lungs...)"
    *   Candidate senses:
        1.  Malignant growth/tumor (medical).
        2.  Astrology (person born in Cancer).
        3.  Constellation.
        4.  Zodiac sign.
        5.  Genus of crabs.

    *   The context discusses "Alimta," a "solution for infusion," "active substance pemetrexed," "treat two types of cancer," "pleural mesothelioma," "anticancer medicine," "chemotherapy," and "non-small cell lung cancer."
    *   This is clearly a medical context referring to a disease.

    *   Sense 1: "any malignant growth or tumor caused by abnormal and uncontrolled cell division..." - This matches perfectly.
    *   Sense 2: Astrology (person) - Incorrect.
    *   Sense 3: Constellation - Incorrect.
    *   Sense 4: Zodiac sign - Incorrect.
    *   Sense 5: Genus of crabs - Incorrect.

    *   The best sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: lining
Target surface form: lining
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the <t>lining</t> of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=lining%1:06:00:: | definition=a protective covering that protects an inside surface | synonyms=liner
2. sense_key=lining%1:06:01:: | definition=a piece of cloth that is used as the inside surface of a garment | synonyms=liner
3. sense_key=lining%1:04:01:: | definition=providing something with a surface of a different material | synonyms=facing
4. sense_key=lining%1:04:00:: | definition=the act of attaching an inside lining (to a garment or curtain etc.)

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `lining`
    *   Target surface form: `lining`
    *   Context: "...pleural mesothelioma (cancer of the <t>lining</t> of the lungs that is usually caused by exposure to asbestos)."
    *   Candidate senses:
        1.  `lining%1:06:00::`: a protective covering that protects an inside surface (synonym: liner)
        2.  `lining%1:06:01::`: a piece of cloth that is used as the inside surface of a garment (synonym: liner)
        3.  `lining%1:04:01::`: providing something with a surface of a different material (synonym: facing)
        4.  `lining%1:04:00::`: the act of attaching an inside lining (to a garment or curtain etc.)

    *   The context refers to the "lining of the lungs" in the context of pleural mesothelioma.
    *   In anatomy, a lining is a membrane or layer of tissue that covers an internal surface.

    *   Sense 1: "a protective covering that protects an inside surface". This fits the anatomical description of the pleura (the lining of the lungs).
    *   Sense 2: "a piece of cloth... of a garment". Incorrect (not a garment).
    *   Sense 3: "providing something with a surface of a different material". This is a gerund/action (the act of lining). Incorrect.
    *   Sense 4: "the act of attaching an inside lining". This is an action. Incorrect.

    *   Sense 1 is the only one that describes a physical covering of an inside surface, which matches the biological context of the lung lining.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cause
Target surface form: caused
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually <t>caused</t> by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cause%2:36:00:: | definition=give rise to; cause to happen or occur, not always intentionally | synonyms=do, make | examples=cause a commotion; make a stir
2. sense_key=cause%2:32:00:: | definition=cause to do; cause to act in a specified manner | synonyms=induce, stimulate, have, get, make | examples=The ads induced me to buy a VCR; My children finally got me to buy a computer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `cause`
    *   Target surface form: `caused`
    *   Context: "...pleural mesothelioma (cancer of the lining of the lungs that is usually <t>caused</t> by exposure to asbestos)."
    *   Candidate senses:
        1.  `cause%2:36:00::`: give rise to; cause to happen or occur, not always intentionally. (Synonyms: do, make. Example: cause a commotion).
        2.  `cause%2:32:00::`: cause to do; cause to act in a specified manner. (Synonyms: induce, stimulate, have, get, make. Example: The ads induced me to buy a VCR).

    *   The sentence says "cancer... that is usually caused by exposure to asbestos."
    *   Here, "caused" means that exposure to asbestos *gives rise to* or *makes happen* the cancer.
    *   It is not about causing someone to *do* something or *act* in a certain way (which is what sense 2 describes).

    *   Sense 1: "give rise to; cause to happen or occur" -> Fits perfectly. Asbestos exposure gives rise to the cancer.
    *   Sense 2: "cause to do; cause to act in a specified manner" -> Does not fit. Cancer is not "acting" in a manner caused by asbestos in the sense of an action or behavior.

    *   Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is <t>used</t> together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "Alimta is <t>used</t> together with cisplatin (another anticancer medicine)..."
    *   General context: Medical description of a drug (Alimta) and its application/administration for treating cancer.

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (Synonyms: utilize, utilise, apply, employ).
    *   Sense 2: `take or consume (regularly or habitually)` (Synonyms: habituate).
    *   Sense 3: `use up, consume fully` (Synonyms: expend).
    *   Sense 4: `seek or achieve an end by using to one's advantage`.
    *   Sense 5: `avail oneself to` (Synonyms: practice, apply).
    *   Sense 6: `habitually do something (use only in the past tense)`.

    *   The sentence is: "Alimta is used together with cisplatin..."
    *   This means Alimta is *employed* or *utilized* as a treatment.
    *   It is not about consuming a drug habitually (Sense 2), using it up (Sense 3), manipulating someone/something for advantage (Sense 4), practicing a religion/principle (Sense 5), or a past habit (Sense 6).
    *   Sense 1 fits perfectly: "put into service; make work or employ for a particular purpose". In this case, the purpose is treating cancer.

    *   Sense 1: "put into service; make work or employ for a particular purpose" -> Alimta is employed for the purpose of treating cancer. (Correct)
    *   Sense 2: "take or consume (regularly or habitually)" -> While patients "use" drugs, the sentence "Alimta is used together with cisplatin" describes the *application* of the drug in a medical protocol, not the habit of the patient.
    *   Sense 3: "use up" -> Not applicable.
    *   Sense 4: "seek or achieve an end by using to one's advantage" -> This usually implies manipulation or exploitation. Not applicable.
    *   Sense 5: "avail oneself to" -> Not applicable.
    *   Sense 6: "habitually do something" -> Not applicable.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer <t>medicine</t>) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicine`
    *   Context: "Alimta is used together with cisplatin (another anticancer <t>medicine</t>)..."
    *   Candidate senses:
        1.  `medicine%1:09:00::`: branches of medical science (medical specialty).
        2.  `medicine%1:06:00::`: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).
        3.  `medicine%1:04:00::`: the learned profession (practice of medicine).
        4.  `medicine%1:04:02::`: punishment for one's actions (take your medicine).

    *   The sentence says "cisplatin (another anticancer medicine)".
    *   Cisplatin is a chemical substance used to treat cancer.
    *   This fits the definition of a medication or medicinal drug.

    *   Sense 1: Medical specialty (e.g., cardiology). Not applicable.
    *   Sense 2: Medication/drug. Fits perfectly.
    *   Sense 3: Profession/study (e.g., studying medicine). Not applicable.
    *   Sense 4: Punishment. Not applicable.

    *   The best sense is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the <t>cancer</t> is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: A medical description of the drug Alimta, used to treat pleural mesothelioma and non-small cell lung cancer. The specific sentence is: "Alimta is used together with cisplatin (another anticancer medicine) when the <t>cancer</t> is unresectable..."
    *   Candidate senses:
        1.  `cancer%1:26:00::`: malignant growth or tumor caused by abnormal and uncontrolled cell division.
        2.  `cancer%1:18:00::`: (astrology) a person born while the sun is in Cancer.
        3.  `cancer%1:17:00::`: a small zodiacal constellation.
        4.  `cancer%1:15:00::`: the fourth sign of the zodiac.
        5.  `cancer%1:05:00::`: type genus of the family Cancridae.

    *   The context is clearly medical, discussing a drug (Alimta), chemotherapy, malignant growths, and lung cancer.
    *   The word "cancer" refers to the disease being treated.

    *   Sense 1: Malignant growth/tumor (Medical). Matches perfectly.
    *   Sense 2: Astrology (Person). Incorrect.
    *   Sense 3: Astronomy (Constellation). Incorrect.
    *   Sense 4: Astrology (Zodiac sign). Incorrect.
    *   Sense 5: Biology (Genus of crabs). Incorrect.

    *   The best sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: remove
Target surface form: removed
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be <t>removed</t> by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=remove%2:30:00:: | definition=remove something concrete, as by lifting, pushing, or taking off, or remove something abstract | synonyms=take, take away, withdraw | examples=remove a threat; remove a wrapper
2. sense_key=remove%2:41:00:: | definition=remove from a position or an office
3. sense_key=remove%2:40:00:: | definition=dispose of | synonyms=get rid of | examples=Get rid of these old shoes!; The company got rid of all the dead wood
4. sense_key=remove%2:41:02:: | definition=cause to leave | synonyms=take out, move out | examples=The teacher took the children out of the classroom
5. sense_key=remove%2:38:00:: | definition=shift the position or location of, as for business, legal, educational, or military purposes | synonyms=transfer | examples=He removed his children to the countryside; Remove the troops to the forest surrounding the city
6. sense_key=remove%2:30:01:: | definition=go away or leave | synonyms=absent | examples=He absented himself
7. sense_key=remove%2:41:01:: | definition=kill intentionally and with premeditation | synonyms=murder, slay, hit, dispatch, bump off, off | examples=The mafia boss ordered his enemies murdered
8. sense_key=remove%2:30:02:: | definition=get rid of something abstract | synonyms=take away | examples=The death of her mother removed the last obstacle to their marriage; God takes away your sins

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `remove`
    *   Target surface form: `removed`
    *   Context: "...when the cancer is unresectable (cannot be <t>removed</t> by surgery alone)..."

    *   Sense 1: remove something concrete (lifting, pushing, taking off) or abstract. Synonyms: take, take away, withdraw. Examples: remove a threat, remove a wrapper.
    *   Sense 2: remove from a position or office.
    *   Sense 3: dispose of. Synonyms: get rid of. Examples: Get rid of these old shoes.
    *   Sense 4: cause to leave. Synonyms: take out, move out.
    *   Sense 5: shift position/location (transfer).
    *   Sense 6: go away or leave.
    *   Sense 7: kill intentionally (murder).
    *   Sense 8: get rid of something abstract.

    *   The context is medical: "cancer is unresectable (cannot be removed by surgery alone)".
    *   "Removed by surgery" refers to the physical extraction of a tumor or cancerous tissue from the body.
    *   This is a concrete action (taking something out of the body).

    *   Sense 1: "remove something concrete, as by lifting, pushing, or taking off". This fits the physical extraction of a tumor.
    *   Sense 3: "dispose of" / "get rid of". While surgery "gets rid of" the cancer, "remove" in a surgical context specifically refers to the physical act of taking it out.
    *   Sense 7: "kill intentionally". Not applicable to a tumor in this sense.
    *   Sense 8: "get rid of something abstract". Cancer is concrete.

    *   Sense 1 is the most accurate description of surgical removal (taking something concrete out).

    *   Sense 1: remove something concrete... (e.g., remove a wrapper).
    *   Surgical removal of a tumor is the removal of a concrete object from a location.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: surgery
Target surface form: surgery
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by <t>surgery</t> alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=surgery%1:09:00:: | definition=the branch of medical science that treats disease or injury by operative procedures | examples=he is professor of surgery at the Harvard Medical School
2. sense_key=surgery%1:06:01:: | definition=a room where a doctor or dentist can be consulted | examples=he read the warning in the doctor's surgery
3. sense_key=surgery%1:06:00:: | definition=a room in a hospital equipped for the performance of surgical operations | synonyms=operating room, OR, operating theater, operating theatre | examples=great care is taken to keep the operating rooms aseptic
4. sense_key=surgery%1:04:01:: | definition=a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body | synonyms=operation, surgical operation, surgical procedure, surgical process | examples=they will schedule the operation as soon as an operating room is available; he died while undergoing surgery

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
*   Target lemma: `surgery`
    *   Target surface form: `surgery`
    *   Context: "...when the cancer is unresectable (cannot be removed by <t>surgery</t> alone)..."
    *   Candidate senses:
        1.  `surgery%1:09:00::`: branch of medical science (academic/field).
        2.  `surgery%1:06:01::`: doctor's office/consultation room.
        3.  `surgery%1:06:00::`: operating room (physical location).
        4.  `surgery%1:04:01::`: medical procedure involving an incision (the act of operating).

    *   The phrase is "cannot be removed by surgery alone".
    *   "Removed by surgery" refers to the *act* or *procedure* of removing a tumor, not the field of science, the doctor's office, or the operating room itself.
    *   Comparing with sense 4: "a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body". This fits perfectly.

    *   Sense 1: Field of study (Incorrect).
    *   Sense 2: Office (Incorrect).
    *   Sense 3: Operating room (Incorrect).
    *   Sense 4: Medical procedure (Correct).