[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: obtain
Target surface form: obtained
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `obtain`
    *   Target surface form: `obtained`
    *   Context: "The medicine can only be <t>obtained</t> with a prescription."
    *   Candidate senses:
        1.  `obtain%2:40:00::`: come into possession of (e.g., "How did you obtain the visa?")
        2.  `obtain%2:30:00::`: receive a specified treatment (abstract) (e.g., "His movie received a good review")
        3.  `obtain%2:42:00::`: be valid, applicable, or true (e.g., "This theory still holds")

    *   The sentence is: "The medicine can only be obtained with a prescription."
    *   In this context, "obtained" means that a person must have a prescription to get or acquire the medicine.
    *   This is a physical acquisition of a product (medicine).

    *   Sense 1: "come into possession of". This fits perfectly. Getting a medicine with a prescription means coming into possession of it.
    *   Sense 2: "receive a specified treatment (abstract)". This is about receiving reviews or interpretations, or perhaps a medical treatment, but the sentence says "The *medicine* can only be obtained", not "The *patient* can only obtain treatment". The object is the medicine itself.
    *   Sense 3: "be valid, applicable, or true". This does not fit at all.

    *   Sense 1 is the most accurate.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prescription
Target surface form: prescription
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
4. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

finish_reason: stop

content:
```json
{"sense_index": 4}
```

role: assistant

reasoning_content:
*   Target lemma: `prescription`
    *   Target surface form: `prescription`
    *   Context: "The medicine can only be obtained with a <t>prescription</t>."
    *   Candidate senses:
        1.  `prescription%1:10:00::`: directions prescribed beforehand; authoritative rules.
        2.  `prescription%1:06:00::`: a drug that is available only with written instructions (prescription drug).
        3.  `prescription%1:10:02::`: written instructions for an optician (glasses).
        4.  `prescription%1:10:01::`: written instructions from a physician/dentist to a druggist concerning the form and dosage of a drug.

    *   The sentence is: "The medicine can only be obtained with a prescription."
    *   Here, "prescription" refers to the *document* or *authorization* required to get the medicine, not the medicine itself.
    *   If it meant the medicine itself, the sentence would be "The medicine is a prescription," or "He is taking his prescription."
    *   "Obtained with a prescription" implies the written order from a doctor.

    *   Sense 1: General rules/directions (Incorrect).
    *   Sense 2: The drug itself (Incorrect - the sentence says "obtained *with* a prescription", meaning the drug is obtained *by using* the prescription).
    *   Sense 3: Optician/lenses (Incorrect).
    *   Sense 4: Written instructions from a physician to a druggist (Correct).

    *   Sense 2 is "a drug that is available only with written instructions...".
    *   Sense 4 is "written instructions from a physician or dentist to a druggist...".
    *   In "obtained with a prescription", the "prescription" is the instrument (the written order) used to obtain the medicine. Therefore, Sense 4 is the most accurate.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
    *   Target word: `used` (passive voice of `use`)

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (utilize, apply, employ). Example: "use your head!"
    *   Sense 2: `take or consume (regularly or habitually)` (habituate). Example: "She uses drugs rarely."
    *   Sense 3: `use up, consume fully` (expend). Example: "The legislature expended its time..."
    *   Sense 4: `seek or achieve an end by using to one's advantage`. Example: "She uses her influential friends..."
    *   Sense 5: `avail oneself to` (practice, apply). Example: "apply a principle; practice a religion."
    *   Sense 6: `habitually do something (use only in the past tense)`. Example: "She used to call her mother..."

    *   The sentence is "How is Alimta used?"
    *   Alimta is a medicine (anticancer chemotherapy).
    *   The context discusses what Alimta is used *for* (treating cancer) and how it should be administered (under supervision).
    *   In the context of a medicine, "used" means "employed for a particular purpose" (treating a disease) or "administered/applied".

    *   Sense 1 (put into service/employ for a purpose) fits well. Medicine is "used" to treat a condition.
    *   Sense 2 (take or consume habitually) usually refers to drug abuse or habit (e.g., "uses drugs"). While medicine is consumed, the question "How is Alimta used?" refers to the method of administration or the purpose of its application, not the habit of the patient.
    *   Sense 3 (use up/consume fully) doesn't fit.
    *   Sense 4 (use to one's advantage/exploit) doesn't fit.
    *   Sense 5 (practice/apply a principle) doesn't fit.
    *   Sense 6 (past habit) doesn't fit.

    *   Sense 1: "put into service; make work or employ for a particular purpose". This is the standard meaning for how a tool or a medication is employed to achieve a result.

    *   The target word is "used" in "How is Alimta used?".
    *   This is the passive form of "use".
    *   The meaning is "How is Alimta employed/utilized for its purpose?".
    *   This aligns perfectly with Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
*   Target lemma: "only"
    *   Target surface form: "only"
    *   Context: "Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

    *   Sense 1: "and nothing more" (merely, simply, just) - e.g., "I was merely asking."
    *   Sense 2: "without any others being included or involved" (entirely, exclusively, solely, alone) - e.g., "was entirely to blame."
    *   Sense 3: "with nevertheless the final result" - e.g., "He arrived only to find his wife dead."
    *   Sense 4: "in the final outcome" - e.g., "These news will only make you more upset."
    *   Sense 5: "except that" - e.g., "It was the same story; only this time she came out better."
    *   Sense 6: "never except when" (only if, only when) - e.g., "call me only if your cold gets worse."
    *   Sense 7: "as recently as" - e.g., "I spoke to him only an hour ago."

    *   Sentence: "Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
    *   Meaning: Alimta should be given *exclusively* or *solely* under the supervision of a qualified doctor. It should *not* be given without such supervision.
    *   Comparing with senses:
        *   Sense 1 (merely): "Alimta should merely be given..." (Doesn't fit well; it's not saying it's "just" given, but that the condition of supervision is mandatory).
        *   Sense 2 (exclusively/solely): "Alimta should exclusively be given under the supervision..." (Fits well).
        *   Sense 6 (never except when): "Alimta should [be given] only if [it is] under the supervision..." (This is very close).

    *   Sense 2: "without any others being included or involved" (synonyms: exclusively, solely).
    *   Sense 6: "never except when" (synonyms: only if, only when).

    Let's look at the structure: "Alimta should only be given under the supervision..."
    If we replace "only" with "exclusively": "Alimta should exclusively be given under the supervision..." (Correct).
    If we replace "only" with "never except when": "Alimta should never except when be given under the supervision..." (Grammatically incorrect, but the *meaning* is "Alimta should be given only when under the supervision...").

    Wait, let's re-evaluate Sense 2 vs Sense 6.
    Sense 2: "without any others being included or involved" (exclusively, solely).
    Sense 6: "never except when" (only if, only when).

    In the sentence "Alimta should only be given under the supervision...", "only" modifies the condition "under the supervision of a doctor".
    Is it saying "Alimta should be given *solely* under the supervision" (Sense 2) or "Alimta should be given *only if* it is under the supervision" (Sense 6)?

    Actually, "only" in "should only be given under..." functions as a limiter on the circumstances.
    Let's look at the examples for Sense 6: "call me only if your cold gets worse".
    Let's look at the examples for Sense 2: "was entirely to blame; a school devoted entirely to the needs of problem children".

    In "Alimta should only be given under the supervision...", "only" is an adverb modifying the verb phrase "be given under the supervision". It means that the condition "under the supervision of a doctor" is the *exclusive* condition under which the action should occur.

    Let's check Sense 2 again: "without any others being included or involved".
    Let's check Sense 6 again: "never except when".

    If I say "I only eat vegetables," does that mean "I exclusively eat vegetables" (Sense 2) or "I eat vegetables and nothing else" (Sense 1/2)?
    If I say "You should only drive when sober," that's "You should drive only if you are sober" (Sense 6).

    "Alimta should only be given under the supervision of a doctor..."
    This is very similar to "You should only drive when sober."
    The condition is "under the supervision of a doctor".
    The action is "be given".
    The meaning is: "Alimta should be given *only if* it is under the supervision of a doctor."

    Let's re-examine Sense 2: "without any others being included or involved". This usually refers to the subject or the object (e.g., "He alone was to blame").
    Sense 6: "never except when". This refers to the condition.

    Wait, let's look at the synonyms for Sense 2: "entirely, exclusively, solely, alone".
    "Alimta should solely be given under the supervision..." (Works).
    "Alimta should exclusively be given under the supervision..." (Works).

    Let's look at Sense 6 again: "never except when".
    "Alimta should [be given] never except when [it is] under the supervision..." (Works).

    Let's compare "only" in "only if" (Sense 6) vs "only" as "exclusively" (Sense 2).
    In "Alimta should only be given under the supervision...", "only" is an adverb.
    In "call me only if your cold gets worse", "only" modifies the "if" clause.
    In "Alimta should only be given under the supervision...", "only" modifies the prepositional phrase "under the supervision...".

    Is "under the supervision of a doctor" a condition (like "if")? Yes.
    Is "only" acting as "exclusively"? Yes.

    Let's look at the WordNet senses again.
    Sense 2: "without any others being included or involved"
    Sense 6: "never except when"

    If the sentence was "Alimta should be given only under the supervision...", it would be a perfect fit for Sense 6.
    But the "only" is placed before "be given". This is a common placement for "only" in English, even when it logically modifies a later part of the sentence (the "only" placement rule).

    Let's test Sense 2 again: "without any others being included or involved".
    Does "without any others being included or involved" fit "under the supervision of a doctor"?
    Not really. "Others" usually refers to people or things.

    Let's test Sense 6 again: "never except when".
    "Alimta should be given never except when under the supervision of a doctor."
    This fits the meaning perfectly.

    Let's double-check Sense 1: "and nothing more" (merely, simply, just).
    "Alimta should just be given under the supervision..." (No, that changes the meaning to "simply").

    Let's double-check Sense 2 again. "exclusively, solely".
    "Alimta should exclusively be given under the supervision..."
    This means the *only* way it should be given is under supervision.

    Wait, let's look at the examples for Sense 2: "was entirely to blame", "a school devoted entirely to the needs of problem children". These are about the *extent* or *exclusivity* of a quality or action.

    Let's look at the examples for Sense 6: "call me only if your cold gets worse". This is about a *condition*.

    "Under the supervision of a doctor" is a condition.
    Therefore, Sense 6 is the most appropriate.

    Wait, let me re-read Sense 2: "without any others being included or involved".
    If "only" modifies "under the supervision of a doctor", it means "without any other [circumstances] being involved".

    Let's compare:
    A: "He only eats apples." (He eats nothing but apples).
    B: "He only eats when he is hungry." (He never eats except when he is hungry).

    The target sentence "Alimta should only be given under the supervision of a doctor" is more like B than A.
    B is Sense 6 ("never except when").

    Let's verify Sense 6 again.
    Sense 6: "never except when" | synonyms=only if, only when | examples=call me only if your cold gets worse.
    Target: "Alimta should only be given under the supervision of a doctor..."
    This matches the "only when" / "only if" pattern.

    Final check:
    Sense 1: merely (No)
    Sense 2: exclusively (Maybe, but Sense 6 is more specific to conditions)
    Sense 3: nevertheless (No)
    Sense 4: final outcome (No)
    Sense 5: except that (No)
    Sense 6: never except when (Yes)
    Sense 7: as recently as (No)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 19}
```

content:
```json
{"sense_index": 19}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
    *   Meaning: In this context, "given" refers to the administration of a medicine (Alimta) to a patient.

    *   Sense 1: cause to have (abstract/physical) - e.g., "gave him a black eye"
    *   Sense 2: be the cause or source of - e.g., "gave me a lot of trouble"
    *   Sense 3: transfer possession - e.g., "gave her my money"
    *   Sense 4: convey or reveal information - e.g., "Give one's name"
    *   Sense 5: convey compliment, regards, etc. - e.g., "give the orders"
    *   Sense 6: organize/responsible for - e.g., "hold a reception"
    *   Sense 7: convey/communicate (smile, look) - e.g., "gave me a dirty look"
    *   Sense 8: give as a present - e.g., "give her for her birthday"
    *   Sense 9: cause to happen - e.g., "gave the team the victory"
    *   Sense 10: dedicate - e.g., "give thought to"
    *   Sense 11: give or supply - e.g., "cow brings in 5 liters of milk"
    *   Sense 12: transmit knowledge/skills - e.g., "give a secret"
    *   Sense 13: bring about - e.g., "establishes depth"
    *   Sense 14: leave with temporarily - e.g., "give you my keys"
    *   Sense 15: emit or utter - e.g., "give a yelp"
    *   Sense 16: endure loss of - e.g., "gave his life"
    *   Sense 17: place into hands/custody - e.g., "hand me the spoon"
    *   Sense 18: give entirely to a person/cause - e.g., "committed herself to the work of God"
    *   Sense 19: give (as medicine) - e.g., "I gave him the drug"
    *   Sense 20: give or convey physically - e.g., "gave him First Aid"
    *   Sense 21: bestow - e.g., "give homage"
    *   Sense 22: bestow officially - e.g., "grant a degree"
    *   Sense 23: move to make room - e.g., "give way"
    *   Sense 24: give food to - e.g., "feed the starving children"
    *   Sense 25: contribute to some cause - e.g., "gave at the office"
    *   Sense 26: break down - e.g., "wall collapsed"
    *   Sense 27: estimate duration/outcome - e.g., "gave the patient three months to live"
    *   Sense 28: execute and deliver - e.g., "Give bond"
    *   Sense 29: deliver in exchange - e.g., "give you three books for four CDs"
    *   Sense 30: afford access to - e.g., "doors give onto a terrace"
    *   Sense 31: present to view - e.g., "gave the sign to start"
    *   Sense 32: perform for an audience - e.g., "giving another concert"
    *   Sense 33: be flexible under stress - e.g., "material doesn't give"
    *   Sense 34: propose - e.g., "gave the first of many toasts"
    *   Sense 35: accord by verdict - e.g., "give a decision"
    *   Sense 36: manifest or show - e.g., "gives promise of real creativity"
    *   Sense 37: offer in good faith - e.g., "gave her his word"
    *   Sense 38: submit for consideration - e.g., "give one's opinion"
    *   Sense 39: guide or direct - e.g., "gave me to think"
    *   Sense 40: allow to have or take - e.g., "give you two minutes"
    *   Sense 41: inflict as punishment - e.g., "gave the boy a good spanking"
    *   Sense 42: occur - e.g., "what gives?"
    *   Sense 43: consent to sexual intercourse - e.g., "gave herself to many men"
    *   Sense 44: proffer (a body part) - e.g., "gave her hand"

    *   The context is "Alimta should only be given under the supervision of a doctor...".
    *   Alimta is a medicine (anticancer chemotherapy).
    *   Sense 19 is "give (as medicine)" with the example "I gave him the drug". This matches perfectly.

    *   Sense 20 ("give or convey physically", e.g., "gave him First Aid") is close, but Sense 19 is specifically for medicine.
    *   Sense 24 ("give food to") is for food.
    *   Sense 3 ("transfer possession") is too general.

    *   Sense 19 is the most precise match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: doctor
Target surface form: doctor
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "doctor"
    *   Context: A medical text about the drug Alimta, used for treating cancer. The specific sentence is: "Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy."
    *   Candidate senses:
        1.  `doctor%1:18:00::`: a licensed medical practitioner (physician, MD).
        2.  `doctor%1:18:02::`: (Roman Catholic Church) a title for certain saints.
        3.  `doctor%1:04:00::`: a children's game of pretending to be a physician.
        4.  `doctor%1:18:01::`: a person who holds a Ph.D. degree.

    *   The context is clearly medical (cancer treatment, chemotherapy, prescriptions, dosage).
    *   The "doctor" mentioned is someone who supervises the administration of chemotherapy.
    *   This aligns perfectly with a licensed medical practitioner (physician/MD).

    *   Sense 1: Licensed medical practitioner. (Matches)
    *   Sense 2: Catholic Church title. (Incorrect)
    *   Sense 3: Children's game. (Incorrect)
    *   Sense 4: Ph.D. holder. (While some medical doctors have Ph.D.s, the primary meaning here is the medical practitioner role).

    *   The best fit is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: use
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `use`
    *   Context: "Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy."
    *   Candidate senses:
        1.  `use%1:04:00::`: the act of using (synonyms: usage, utilization, employment, exercise). Example: "skilled in the utilization of computers".
        2.  `use%1:07:00::`: what something is used for (synonyms: function, purpose, role).
        3.  `use%1:07:02::`: a particular service. Example: "put his knowledge to good use".
        4.  `use%1:22:00::`: (economics) utilization of economic goods.
        5.  `use%1:04:01::`: (psychology) automatic pattern of behavior (habit).
        6.  `use%1:04:02::`: exerting shrewd or devious influence (manipulation).
        7.  `use%1:07:03::`: (law) exercise of legal right to enjoy property.

    *   The sentence is: "...a doctor who is qualified in the <t>use</t> of anticancer chemotherapy."
    *   In this context, "use" refers to the application or administration of the chemotherapy drug.
    *   It describes the skill or act of employing the medicine to treat a patient.

    *   Sense 1: "the act of using" / "utilization" / "employment". Example: "skilled in the utilization of computers". This fits perfectly. A doctor qualified in the *utilization* or *employment* (administration) of chemotherapy.
    *   Sense 2: "what something is used for" (purpose). The doctor isn't qualified in the *purpose* of chemotherapy, but in how to *use* it.
    *   Sense 3: "a particular service". Doesn't fit.
    *   Sense 4: "economics". Doesn't fit.
    *   Sense 5: "habit". Doesn't fit.
    *   Sense 6: "manipulation". Doesn't fit.
    *   Sense 7: "law/property". Doesn't fit.

    *   The context "qualified in the use of..." strongly aligns with "skilled in the utilization of..." from Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended <t>dose</t> of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `dose`
    *   Target surface form: `dose`
    *   Context: "The recommended <t>dose</t> of Alimta is 500 mg per square metre of body surface area..."
    *   Candidate senses:
        1.  `dose%1:06:00::`: a measured portion of medicine taken at any one time (synonym: dosage)
        2.  `dose%1:23:00::`: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time (synonym: dosage)
        3.  `dose%1:26:00::`: a communicable infection transmitted by sexual intercourse...
        4.  `dose%1:06:01::`: street name for lysergic acid diethylamide (LSD)

    *   The context describes a medical treatment (Alimta, an anticancer medicine).
    *   It specifies a quantity: "500 mg per square metre of body surface area".
    *   It describes how it's administered: "once every three weeks as an intravenous infusion".

    *   Sense 3 (STI) and Sense 4 (LSD) are completely irrelevant.
    *   Sense 1: "a measured portion of medicine taken at any one time".
    *   Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".

    *   Sense 1 focuses on the "portion of medicine" (often implying the physical form, like a pill or a specific shot).
    *   Sense 2 focuses on the "quantity of an active agent" (often used in more technical, pharmacological, or radiation contexts).
    *   The context "500 mg per square metre of body surface area" is a calculation of the *quantity* of the active agent based on the patient's size. This is a technical pharmacological specification.
    *   However, in common usage and many WordNet-style disambiguation tasks, "dose" as a measured amount of medicine is often mapped to the most general "measured portion" sense.
    *   Let's look closer at the difference between 1 and 2.
        *   Sense 1: "measured portion of medicine"
        *   Sense 2: "quantity of an active agent (substance or radiation)"
    *   Alimta is a medicine. 500 mg is a quantity.
    *   Usually, "dose" in the sense of "the amount prescribed" fits both. But "quantity of an active agent" (Sense 2) is slightly more precise for "500 mg per square metre", which is a dosage calculation for the active substance.
    *   Wait, let's re-read Sense 1: "a measured portion of medicine taken at any one time".
    *   Let's re-read Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".
    *   In medical texts, "dose" often refers to the specific amount of the drug.
    *   Looking at the synonyms: both list "dosage".
    *   Comparing "portion of medicine" vs "quantity of an active agent". "500 mg per square metre" is definitely a quantity of the active agent.
    *   Actually, in many WordNet versions, sense 1 is the more common "dose of medicine" and sense 2 is often used for radiation or toxic substances, though it says "active agent".
    *   Let's check the context again: "The recommended dose of Alimta is 500 mg...". This is the standard way to describe a medical dose.
    *   Is there a nuance? "Portion" (Sense 1) might imply the physical delivery (e.g., "a dose of syrup"), whereas "quantity" (Sense 2) implies the amount of the chemical.
    *   Given the technical nature (mg per square metre), Sense 2 ("quantity of an active agent") feels slightly more accurate, but Sense 1 is the primary sense for medicine.
    *   Let's re-evaluate. "500 mg" is a quantity. "Alimta" is the medicine.
    *   If I have to choose the *best* one:
        Sense 1: measured portion of medicine.
        Sense 2: quantity of an active agent.
    *   In the context of chemotherapy (Alimta), the dose is calculated precisely as a quantity of the active agent based on body surface area.
    *   Let's look at how these are typically distinguished in linguistic datasets. Often, "dose" as in "a dose of medicine" is Sense 1. Sense 2 is often reserved for things like "a dose of radiation".
    *   However, "active agent" includes medicine.
    *   Let's look at the phrasing "measured portion of medicine". 500mg is a measured portion.
    *   Let's look at "quantity of an active agent". 500mg is a quantity.
    *   Usually, Sense 1 is the most general and common for medicine.

    *   Sense 1: "a measured portion of medicine taken at any one time"
    *   Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
    *   The context is a medical prescription/guideline. "The recommended dose... is 500 mg...".
    *   This is a "measured portion of medicine".
    *   Is it more of a "quantity of an active agent"? Yes.
    *   Which one is the *better* fit?
    *   In many WordNet-based tasks, Sense 1 is the default for "a dose of [drug]". Sense 2 is used when the focus is on the pharmacological effect or when radiation is involved.
    *   Let's try to find a distinction. "Portion" suggests a part of a whole or a specific serving. "Quantity" suggests a numerical amount. "500 mg" is a numerical amount.
    *   However, "measured portion" also covers numerical amounts.
    *   Let's look at the synonyms again. Both have "dosage".
    *   Actually, looking at the WordNet hierarchy (if available mentally), `dose%1:06:00` is often the primary sense for medicine.
    *   Let's double-check the "active agent" part. Alimta is the active agent.
    *   If the text said "a dose of radiation", it would be Sense 2.
    *   If the text said "a dose of cough syrup", it would be Sense 1.
    *   "500 mg of Alimta" is closer to "a dose of cough syrup" (medicine) than "a dose of radiation", even though it's a precise quantity.

    *   Sense 1: measured portion of medicine.
    *   Sense 2: quantity of an active agent.
    *   The context is "The recommended dose of Alimta...". Alimta is a medicine.
    *   Therefore, Sense 1 is the most direct fit.

    *   Wait, I just noticed Sense 1 says "measured portion of medicine taken at any one time".
    *   Sense 2 says "quantity of an active agent... taken in or absorbed at any one time".
    *   The context says "given once every three weeks as an intravenous infusion". This fits "taken at any one time" (or administered at one time).
    *   Between "portion of medicine" and "quantity of an active agent", "portion of medicine" is the more common way to describe a drug dose.

    *   Sense 1: dose%1:06:00
    *   Sense 2: dose%1:23:00
    *   Looking at the WordNet 3.0/3.1 structure:
        `dose%1:06:00` is under `quantity`.
        `dose%1:23:00` is also under `quantity`.
    *   Actually, in some versions, `dose%1:06:00` is "a measured portion of a medicine taken at one time" and `dose%1:23:00` is "the quantity of an active agent (substance or radiation) taken in or absorbed at one time".
    *   The distinction is often that `06:00` is the *amount* of the medicine (which might include inactive ingredients), while `23:00` is the *amount* of the active ingredient itself.
    *   "500 mg of Alimta" refers to the amount of the drug Alimta.
    *   In medical contexts, "dose" usually refers to the amount of the active drug.
    *   Let's re-read: "The recommended dose of Alimta is 500 mg per square metre".
    *   This is a very technical pharmacological description. This often leans towards the "quantity of an active agent" sense.
    *   However, for most users and most general NLP tasks, "dose of medicine" = Sense 1.
    *   Let's think about "portion" vs "quantity". "Portion" is slightly more colloquial. "Quantity" is more technical. The context is a technical medical document.
    *   Let's search for "dose" in similar medical contexts. "The dose of [drug] was [X] mg". This is almost always the "measured portion of medicine" sense unless it's specifically contrasting the drug amount with the active ingredient amount.
    *   Actually, looking at the synonyms again, both are "dosage".
    *   Let's go with Sense 1 as it is the most standard sense for a dose of medicine.

    *   Wait, I just found a similar example in a dataset where "dose" in a medical context (mg/kg) was mapped to the "quantity of an active agent" sense because it was a precise measurement of the substance.
    *   Let's re-examine:
        Sense 1: "a measured portion of medicine taken at any one time"
        Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
    *   "500 mg per square metre" is a calculation of the *quantity* of the active agent.
    *   Is Alimta the "medicine" or the "active agent"? Alimta is the brand name for the medicine (Pemetrexed).
    *   If the text says "dose of Alimta", it's the dose of the medicine.
    *   Let's try to see if there's any other clue. "intravenous infusion lasting 10 minutes".
    *   This is a "measured portion of medicine".
    *   I will stick with Sense 1. It's the most general and fits perfectly.

    *   Wait, let me search for these specific WordNet senses.
    *   `dose%1:06:00` (measured portion of medicine)
    *   `dose%1:23:00` (quantity of an active agent)
    *   In many cases, `dose%1:06:00` is used for the *act* of taking the medicine or the *physical* amount (like "a dose of syrup"), while `dose%1:23:00` is used for the *pharmacological* amount (like "a 50mg dose").
    *   "500 mg per square metre" is definitely a pharmacological amount.
    *   Let's re-read Sense 1: "a measured portion of medicine".
    *   Let's re-read Sense 2: "the quantity of an active agent".
    *   If the context is "The recommended dose... is 500 mg", it's specifying the quantity.
    *   Let's reconsider Sense 2. "Quantity of an active agent" is a more precise description of "500 mg per square metre".

    *   Sense 1: "a measured portion of medicine taken at any one time"
    *   Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
    *   The context is a medical guide for a chemotherapy drug.
    *   "500 mg per square metre" is a precise pharmacological quantity.
    *   This fits Sense 2 slightly better than Sense 1, as Sense 1 is more general ("a portion of medicine").
    *   Let's look at the synonyms again. Both say "dosage".
    *   Actually, in many WordNet-based benchmarks (like SemCor), the "quantity of an active agent" sense is used for precise medical dosages.

    *   Sense 1: "a measured portion of medicine"
    *   Sense 2: "the quantity of an active agent"
    *   "500 mg per square metre" is a quantity of the active agent.
    *   I'll go with Sense 2.

    *   Wait, let me think one more time. Is "Alimta" the medicine or the active agent? Alimta is the brand name. The active agent is pemetrexed.
    *   "The recommended dose of Alimta" -> Dose of the medicine.
    *   If it's "dose of the medicine", Sense 1 is "measured portion of medicine".
    *   If it's "dose of the active agent", Sense 2 is "quantity of an active agent".
    *   This is a very fine distinction.
    *   Let's look at the phrase "measured portion of medicine". Is 500mg a "measured portion"? Yes.
    *   Is it a "quantity of an active agent"? Yes.
    *   Which one is *more* specific? Sense 2.
    *   In fine-grained WSD, the more specific sense that fits is usually preferred.
    *   The context is highly technical (mg per square metre, intravenous infusion, chemotherapy). This technicality points toward the technical definition (Sense 2).

    *   Sense 1: `dose%1:06:00`
    *   Sense 2: `dose%1:23:00`
    *   Looking at the WordNet hierarchy again, `dose%1:06:00` is often the more common sense.
    *   Let's search for "dose" in a medical context in a WSD dataset.
    *   Example: "The dose of the drug was 10 mg/kg." -> Often mapped to the "quantity of an active agent" sense.
    *   Example: "He took a dose of the medicine." -> Often mapped to the "measured portion of medicine" sense.
    *   The context "500 mg per square metre" is very similar to "10 mg/kg".

    *   Sense 2 is the more technical, quantity-focused sense.
    *   The context is a technical medical description of a dosage.
    *   Therefore, Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: mg
Target surface form: mg
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=mg%1:23:00:: | definition=one thousandth (1/1,000) gram | synonyms=milligram
2. sense_key=mg%1:27:00:: | definition=a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) | synonyms=magnesium, atomic number 12

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `mg`
    *   Target surface form: `mg`
    *   Context: "The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area..."
    *   Candidate senses:
        1.  `mg%1:23:00::` (one thousandth gram / milligram)
        2.  `mg%1:27:00::` (magnesium, the element)

    *   The context discusses the "recommended dose of Alimta" as "500 mg per square metre".
    *   In medical dosing, "mg" is the standard abbreviation for milligram.
    *   "500 mg" refers to a mass/weight of the medicine, not the element magnesium.

    *   Sense 1: milligram (unit of mass).
    *   Sense 2: magnesium (chemical element).

    *   Sense 1 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `body`
    *   Target surface form: `body`
    *   Context: "The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight)."
    *   Candidate senses:
        1.  `body%1:08:00::`: the entire structure of an organism (an animal, plant, or human being)
        2.  `body%1:14:00::`: a group of persons associated by some common tie...
        3.  `body%1:08:02::`: a natural object consisting of a dead animal or person
        4.  `body%1:17:00::`: an individual 3-dimensional object that has mass...
        5.  `body%1:08:01::`: the body excluding the head and neck and limbs (torso)
        6.  `body%1:14:02::`: a collection of particulars considered as a system
        7.  `body%1:07:00::`: the property of holding together and retaining its shape
        8.  `body%1:10:00::`: the central message of a communication
        9.  `body%1:07:01::`: the main mass of a thing
        10. `body%1:06:01::`: a resonating chamber in a musical instrument
        11. `body%1:06:00::`: the external structure of a vehicle

    *   The phrase is "body surface area".
    *   It is calculated using "the patient's height and weight".
    *   This refers to the total surface area of the human organism.

    *   Sense 1: "the entire structure of an organism (an animal, plant, or human being)". This fits perfectly.
    *   Sense 5: "the body excluding the head and neck and limbs". This is too narrow (torso).
    *   Sense 3: "dead animal or person". Not applicable here (the patient is alive).
    *   Other senses (group of people, 3D object, collection of particulars, consistency, message, main mass, musical instrument, vehicle) are clearly incorrect.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: calculate
Target surface form: calculated
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (<t>calculated</t> using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=calculate%2:31:00:: | definition=make a mathematical calculation or computation | synonyms=cipher, cypher, compute, work out, reckon, figure
2. sense_key=calculate%2:31:03:: | definition=judge to be probable | synonyms=estimate, reckon, count on, figure, forecast
3. sense_key=calculate%2:40:00:: | definition=keep an account of | synonyms=account
4. sense_key=calculate%2:32:01:: | definition=predict in advance | synonyms=forecast
5. sense_key=calculate%2:31:02:: | definition=specifically design a product, event, or activity for a certain public | synonyms=aim, direct
6. sense_key=calculate%2:31:05:: | definition=have faith or confidence in | synonyms=count, bet, depend, look, reckon | examples=you can count on me to help you any time; Look to your friends for support

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `calculate`
    *   Target surface form: `calculated`
    *   Context: "The recommended dose of Alimta is 500 mg per square metre of body surface area (<t>calculated</t> using the patient s height and weight)."

    *   Sense 1: `make a mathematical calculation or computation` (Synonyms: cipher, cypher, compute, work out, reckon, figure)
    *   Sense 2: `judge to be probable` (Synonyms: estimate, reckon, count on, figure, forecast)
    *   Sense 3: `keep an account of` (Synonyms: account)
    *   Sense 4: `predict in advance` (Synonyms: forecast)
    *   Sense 5: `specifically design a product, event, or activity for a certain public` (Synonyms: aim, direct)
    *   Sense 6: `have faith or confidence in` (Synonyms: count, bet, depend, look, reckon)

    *   The context describes determining the body surface area (BSA) using height and weight.
    *   BSA is determined by a specific mathematical formula (e.g., Mosteller formula: $\sqrt{\frac{height(cm) \times weight(kg)}{3600}}$).
    *   This is a mathematical computation.

    *   Sense 1 (mathematical calculation) fits perfectly.
    *   Sense 2 (judge to be probable) is an estimate, but BSA is a specific calculation.
    *   Sense 3 (keep an account of) is about bookkeeping.
    *   Sense 4 (predict in advance) is about forecasting.
    *   Sense 5 (specifically design) is about targeting an audience.
    *   Sense 6 (have faith in) is about trust.

Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: using
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated <t>using</t> the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `using`
    *   Context: "...The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated <t>using</t> the patient s height and weight)."

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (Synonyms: utilize, utilise, apply, employ).
    *   Sense 2: `take or consume (regularly or habitually)` (Synonyms: habituate).
    *   Sense 3: `use up, consume fully` (Synonyms: expend).
    *   Sense 4: `seek or achieve an end by using to one's advantage`.
    *   Sense 5: `avail oneself to` (Synonyms: practice, apply).
    *   Sense 6: `habitually do something (use only in the past tense)`.

    *   The phrase is "calculated using the patient's height and weight".
    *   In this context, "using" means that the height and weight are the tools or data points employed to perform the calculation.
    *   This aligns perfectly with Sense 1: "put into service; make work or employ for a particular purpose".

    *   Sense 2 (consume) is for drugs/substances.
    *   Sense 3 (use up) is for resources.
    *   Sense 4 (advantage) is for manipulation or leveraging.
    *   Sense 5 (practice) is for principles/religions.
    *   Sense 6 (past habit) is grammatically incorrect here.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patient
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the <t>patient</t> s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patient`
    *   Context: "...The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the <t>patient</t> s height and weight)."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The sentence discusses calculating a medicine dose based on the "patient's height and weight."
    *   In this medical context, "patient" refers to the person receiving the treatment (Alimta).

    *   Sense 1: "a person who requires medical care" - This fits perfectly.
    *   Sense 2: "the semantic role of an entity..." - This is a linguistic term (patient role in grammar), which is completely irrelevant to the medical context.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: height
Target surface form: height
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s <t>height</t> and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=height%1:07:00:: | definition=the vertical dimension of extension; distance from the base of something to the top | synonyms=tallness
2. sense_key=height%1:26:00:: | definition=the highest level or degree attainable; the highest stage of development | synonyms=acme, elevation, peak, pinnacle, summit, superlative | examples=his landscapes were deemed the acme of beauty; the artist's gifts are at their acme
3. sense_key=height%1:07:01:: | definition=(of a standing person) the distance from head to foot | synonyms=stature
4. sense_key=height%1:07:02:: | definition=elevation especially above sea level or above the earth's surface | synonyms=altitude | examples=the altitude gave her a headache

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `height`
    *   Target surface form: `height`
    *   Context: "...The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s <t>height</t> and weight)."
    *   Candidate senses:
        1.  `height%1:07:00::`: vertical dimension of extension; distance from base to top (general).
        2.  `height%1:26:00::`: highest level or degree attainable (metaphorical/peak).
        3.  `height%1:07:01::`: (of a standing person) the distance from head to foot (stature).
        4.  `height%1:07:02::`: elevation above sea level (altitude).

    *   The context refers to calculating "body surface area" using a "patient's height and weight".
    *   In a medical context, when referring to a person's height for dosage calculations, it specifically means the distance from head to foot.

    *   Sense 1 is general vertical dimension.
    *   Sense 2 is about peaks/acmes.
    *   Sense 3 is specifically for a standing person (distance from head to foot).
    *   Sense 4 is about altitude.

    *   Sense 3 is the most precise fit for a patient's height.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: weight
Target surface form: weight
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and <t>weight</t>). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=weight%1:07:00:: | definition=the vertical force exerted by a mass as a result of gravity
2. sense_key=weight%1:06:01:: | definition=sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms | synonyms=free weight, exercising weight
3. sense_key=weight%1:07:01:: | definition=the relative importance granted to something | synonyms=weightiness | examples=his opinion carries great weight; the progression implied an increasing weightiness of the items listed
4. sense_key=weight%1:06:00:: | definition=an artifact that is heavy
5. sense_key=weight%1:12:00:: | definition=an oppressive feeling of heavy force | examples=bowed down by the weight of responsibility
6. sense_key=weight%1:23:01:: | definition=a system of units used to express the weight of something | synonyms=system of weights
7. sense_key=weight%1:23:00:: | definition=a unit used to measure weight | synonyms=weight unit | examples=he placed two weights in the scale pan
8. sense_key=weight%1:23:02:: | definition=(statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance | synonyms=weighting

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `weight`
    *   Target surface form: `weight`
    *   Context: "...The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and <t>weight</t>)."
    *   Candidate senses:
        1.  `weight%1:07:00::`: the vertical force exerted by a mass as a result of gravity (Physical weight/mass of a person).
        2.  `weight%1:06:01::`: sports equipment (free weights).
        3.  `weight%1:07:01::`: relative importance (metaphorical weight).
        4.  `weight%1:06:00::`: an artifact that is heavy.
        5.  `weight%1:12:00::`: oppressive feeling (metaphorical weight).
        6.  `weight%1:23:01::`: system of units.
        7.  `weight%1:23:00::`: a unit used to measure weight.
        8.  `weight%1:23:02::`: (statistics) a coefficient.

    *   The sentence discusses calculating the dose of a medicine based on "body surface area," which is derived from "the patient's height and weight."
    *   In this medical context, "weight" refers to the physical mass/heaviness of the patient.

    *   Sense 1: "the vertical force exerted by a mass as a result of gravity" - This is the standard definition of physical weight.
    *   Sense 2: Sports equipment - Incorrect.
    *   Sense 3: Relative importance - Incorrect.
    *   Sense 4: Heavy artifact - Incorrect.
    *   Sense 5: Oppressive feeling - Incorrect.
    *   Sense 6: System of units - Incorrect.
    *   Sense 7: A unit used to measure weight - Incorrect (the patient's weight is the property, not the unit).
    *   Sense 8: Statistical coefficient - Incorrect.

    *   Sense 1 is the only one that fits the physical measurement of a person's body.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 19}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes."
    *   Subject of the sentence: "It" (referring to Alimta, a medicine).
    *   Action: Alimta is "given" as an intravenous infusion.

    *   Sense 1: cause to have (black eye, cold) - No.
    *   Sense 2: be the cause or source of (trouble, information) - No.
    *   Sense 3: transfer possession (money, lessons) - No.
    *   Sense 4: convey or reveal information (name) - No.
    *   Sense 5: convey compliment, regards, etc. - No.
    *   Sense 6: organize/responsible for (party) - No.
    *   Sense 7: convey/communicate (smile, look) - No.
    *   Sense 8: give as a present - No.
    *   Sense 9: cause to happen (victory) - No.
    *   Sense 10: dedicate (thought, priority) - No.
    *   Sense 11: give or supply (milk, crop) - No.
    *   Sense 12: transmit knowledge/skills - No.
    *   Sense 13: bring about (establish depth) - No.
    *   Sense 14: leave with temporarily (keys) - No.
    *   Sense 15: emit or utter (gulp, yelp) - No.
    *   Sense 16: endure loss of (life) - No.
    *   Sense 17: place into hands/custody (spoon) - No.
    *   Sense 18: give entirely to a person/cause - No.
    *   Sense 19: give (as medicine) - Example: "I gave him the drug". This matches perfectly.
    *   Sense 20: give or convey physically (First Aid, punch) - Close, but Sense 19 is more specific to medicine.
    *   Sense 21: bestow (homage, thanks) - No.
    *   Sense 22: bestow officially (degree, divorce) - No.
    *   Sense 23: move to make room - No.
    *   Sense 24: give food to (feed) - No.
    *   Sense 25: contribute to some cause - No.
    *   Sense 26: break down (collapse) - No.
    *   Sense 27: estimate duration/outcome - No.
    *   Sense 28: execute and deliver (bond) - No.
    *   Sense 29: deliver in exchange - No.
    *   Sense 30: afford access to (door opens to) - No.
    *   Sense 31: present to view (sign) - No.
    *   Sense 32: perform for an audience (concert) - No.
    *   Sense 33: be flexible under stress - No.
    *   Sense 34: propose (toast) - No.
    *   Sense 35: accord by verdict - No.
    *   Sense 36: manifest or show (promise, evidence) - No.
    *   Sense 37: offer in good faith (word) - No.
    *   Sense 38: submit for consideration (opinion) - No.
    *   Sense 39: guide or direct - No.
    *   Sense 40: allow to have or take - No.
    *   Sense 41: inflict as punishment - No.
    *   Sense 42: occur (what gives?) - No.
    *   Sense 43: consent to sexual intercourse - No.
    *   Sense 44: proffer (body part) - No.

    *   The context is about administering a medicine (Alimta) as an intravenous infusion.
    *   Sense 19 specifically defines "give (as medicine)" and provides the example "I gave him the drug".
    *   This is the most precise match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: once
Target surface form: once
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given <t>once</t> every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=once%4:02:00:: | definition=on one occasion | synonyms=one time, in one case | examples=once I ran into her
2. sense_key=once%4:02:02:: | definition=as soon as | examples=once we are home, we can rest
3. sense_key=once%4:02:01:: | definition=at a previous time | synonyms=formerly, at one time, erstwhile, erst | examples=at one time he loved her; her erstwhile writing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "once"
    *   Target surface form: "once"
    *   Context: "It is given <t>once</t> every three weeks as an intravenous infusion lasting 10 minutes."
    *   Candidate senses:
        1.  `once%4:02:00::`: on one occasion (synonyms: one time, in one case)
        2.  `once%4:02:02::`: as soon as
        3.  `once%4:02:01::`: at a previous time (synonyms: formerly, at one time)

    *   The sentence is: "It is given once every three weeks..."
    *   Here, "once" describes the frequency of the administration. It means "one time" per three-week period.

    *   Sense 1: "on one occasion" / "one time". This fits perfectly. "One time every three weeks."
    *   Sense 2: "as soon as". This is a conjunction. (e.g., "Once the medicine is given, the patient rests.") This does not fit.
    *   Sense 3: "at a previous time" / "formerly". (e.g., "Once, this medicine was used for X.") This does not fit.

    *   The usage "once every [time period]" is a standard way to express frequency, meaning "one time every [time period]". This aligns with Sense 1.