[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
How has Alimta been studied? For the treatment of malignant pleural mesothelioma, Alimta has been studied in one main study in 456 patients who had not received chemotherapy for their disease before. The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the <t>patients</t> survived. What benefit has Alimta shown during the studies?

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text discussing studies on the drug Alimta for treating malignant pleural mesothelioma and non-small cell lung cancer. The specific sentence is: "In all three studies, the main measure of effectiveness was how long the <t>patients</t> survived."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause (linguistics term).

    *   The context is clearly medical. It discusses clinical trials, chemotherapy, cancer treatments, and survival rates of people participating in these studies.
    *   "the main measure of effectiveness was how long the patients survived" refers to the people receiving the treatment.

    *   Sense 1: "a person who requires medical care" fits perfectly.
    *   Sense 2: "the semantic role of an entity..." is a linguistic term (the "patient" in a sentence like "The ball was hit by the boy"). This is completely irrelevant to the medical context.

    *   The correct sense is Sense 1.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survive
Target surface form: survived
Context:
How has Alimta been studied? For the treatment of malignant pleural mesothelioma, Alimta has been studied in one main study in 456 patients who had not received chemotherapy for their disease before. The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients <t>survived</t>. What benefit has Alimta shown during the studies?

Candidate senses:
1. sense_key=survive%2:42:01:: | definition=continue to live through hardship or adversity | synonyms=last, live, live on, go, endure, hold up | examples=We went without water and food for 3 days; These superstitions survive in the backwaters of America
2. sense_key=survive%2:42:02:: | definition=continue in existence after (an adversity, etc.) | synonyms=pull through, pull round, come through, make it | examples=He survived the cancer against all odds
3. sense_key=survive%2:42:00:: | definition=support oneself | synonyms=exist, live, subsist | examples=he could barely exist on such a low wage; Can you live on $2000 a month in New York City?
4. sense_key=survive%2:42:03:: | definition=live longer than | synonyms=outlive, outlast | examples=She outlived her husband by many years

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

finish_reason: stop

content:
```json
{"sense_index": 1}
```

role: assistant

reasoning_content:
*   Target lemma: `survive`
    *   Target surface form: `survived`
    *   Context: "In all three studies, the main measure of effectiveness was how long the patients <t>survived</t>."
    *   Domain: Medical study (oncology - Alimta, chemotherapy, lung cancer, mesothelioma).
    *   Meaning: The duration of time the patients remained alive.

    *   Sense 1: `continue to live through hardship or adversity` (last, live, live on, go, endure, hold up). Example: "We went without water and food for 3 days".
    *   Sense 2: `continue in existence after (an adversity, etc.)` (pull through, pull round, come through, make it). Example: "He survived the cancer against all odds".
    *   Sense 3: `support oneself` (exist, live, subsist). Example: "he could barely exist on such a low wage".
    *   Sense 4: `live longer than` (outlive, outlast). Example: "She outlived her husband by many years".

    *   The sentence "how long the patients survived" refers to the length of time they stayed alive (overall survival is a standard endpoint in cancer trials).
    *   Sense 3 (support oneself) is clearly wrong.
    *   Sense 4 (live longer than) requires a comparison object (e.g., "survived their spouse"), which is not present here.
    *   Sense 2 (continue in existence after an adversity) usually implies getting *through* the event (e.g., "survived the crash", "survived the cancer"). While cancer is the adversity, "how long they survived" refers to the duration of life, not just the act of getting through the disease.
    *   Sense 1 (continue to live through hardship or adversity) includes "live" as a synonym and refers to continuing to live despite hardship. In medical contexts, "survival" (how long they survived) is often mapped to the general sense of continuing to live.

    *   Sense 1: "continue to live through hardship or adversity" (Synonyms: last, live, live on).
    *   Sense 2: "continue in existence after (an adversity, etc.)" (Synonyms: pull through, make it).
    *   In the phrase "how long the patients survived", the focus is on the duration of life (living), not the act of recovering or overcoming the disease (pulling through). If the sentence were "The patient survived the cancer," Sense 2 would be better. But "how long they survived" refers to the time they continued to live.

    *   Sense 1: "continue to live through hardship or adversity" -> "how long the patients [continued to live through the hardship of cancer]".
    *   Sense 2: "continue in existence after (an adversity, etc.)" -> "how long the patients [continued in existence after the adversity]". This doesn't fit the "how long" duration as well as "continue to live".

    Wait, let's look at the synonyms for Sense 1: "last, live, live on". "How long the patients lived" is a perfect paraphrase.

    Let's double-check Sense 2 again: "pull through, pull round, come through, make it". These are binary (you either make it or you don't). "How long" implies a duration of living.

    Therefore, Sense 1 is the best fit.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: benefit
Target surface form: benefit
Context:
For the treatment of malignant pleural mesothelioma, Alimta has been studied in one main study in 456 patients who had not received chemotherapy for their disease before. The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What <t>benefit</t> has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma.

Candidate senses:
1. sense_key=benefit%1:21:00:: | definition=financial assistance in time of need
2. sense_key=benefit%1:07:00:: | definition=something that aids or promotes well-being | synonyms=welfare | examples=for the benefit of all
3. sense_key=benefit%1:10:00:: | definition=a performance to raise money for a charitable cause

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `benefit`
    *   Target surface form: `benefit`
    *   Context: A medical text discussing clinical trials for a drug called Alimta. It asks, "What benefit has Alimta shown during the studies?" and answers that it "increased the survival time of patients."
    *   Candidate senses:
        1.  `benefit%1:21:00::`: financial assistance in time of need.
        2.  `benefit%1:07:00::`: something that aids or promotes well-being (synonym: welfare).
        3.  `benefit%1:10:00::`: a performance to raise money for a charitable cause.

    *   The context is about the effectiveness of a drug (Alimta) in increasing survival time for cancer patients.
    *   "Benefit" here refers to the positive outcome or advantage gained from the treatment.
    *   Sense 1 (financial assistance) is incorrect.
    *   Sense 3 (charity performance) is incorrect.
    *   Sense 2 (something that aids or promotes well-being) fits best, as increasing survival time is a positive outcome that promotes well-being/health.

    *   Sense 2: "something that aids or promotes well-being". This aligns with the medical benefit of increased survival.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: show
Target surface form: shown
Context:
For the treatment of malignant pleural mesothelioma, Alimta has been studied in one main study in 456 patients who had not received chemotherapy for their disease before. The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta <t>shown</t> during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma.

Candidate senses:
1. sense_key=show%2:39:02:: | definition=give an exhibition of to an interested audience | synonyms=demo, exhibit, present, demonstrate | examples=She shows her dogs frequently; We will demo the new software in Washington
2. sense_key=show%2:31:00:: | definition=establish the validity of something, as by an example, explanation or experiment | synonyms=prove, demonstrate, establish, shew | examples=The experiment demonstrated the instability of the compound; The mathematician showed the validity of the conjecture
3. sense_key=show%2:32:00:: | definition=provide evidence for | synonyms=testify, bear witness, prove, evidence | examples=The blood test showed that he was the father; Her behavior testified to her incompetence
4. sense_key=show%2:39:00:: | definition=make visible or noticeable | examples=She showed her talent for cooking; Show me your etchings, please
5. sense_key=show%2:36:00:: | definition=show in, or as in, a picture | synonyms=picture, depict, render | examples=This scene depicts country life; the face of the child is rendered with much tenderness in this painting
6. sense_key=show%2:32:02:: | definition=give expression to | synonyms=express, evince | examples=She showed her disappointment
7. sense_key=show%2:32:01:: | definition=indicate a place, direction, person, or thing; either spatially or figuratively | synonyms=indicate, point, designate | examples=I showed the customer the glove section; He pointed to the empty parking space
8. sense_key=show%2:39:01:: | definition=be or become visible or noticeable | synonyms=show up | examples=His good upbringing really shows; The dirty side will show
9. sense_key=show%2:32:04:: | definition=indicate a certain reading; of gauges and instruments | synonyms=read, register, record | examples=The thermometer showed thirteen degrees below zero; The gauge read `empty'
10. sense_key=show%2:32:03:: | definition=give evidence of, as of records | examples=The diary shows his distress that evening
11. sense_key=show%2:38:00:: | definition=take (someone) to their seats, as in theaters or auditoriums | synonyms=usher | examples=The usher showed us to our seats
12. sense_key=show%2:33:00:: | definition=finish third or better in a horse or dog race | examples=he bet $2 on number six to show

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `show`
    *   Target surface form: `shown`
    *   Context: "What benefit has Alimta <t>shown</t> during the studies?"
    *   Surrounding context: The text discusses clinical studies of a drug (Alimta) for treating cancer, comparing its effectiveness (survival time) against other treatments.

    *   Sense 1: Give an exhibition (demo, exhibit). (Not applicable)
    *   Sense 2: Establish the validity of something, as by an example, explanation or experiment (prove, demonstrate). (Possible: The studies *demonstrated* a benefit).
    *   Sense 3: Provide evidence for (testify, bear witness, prove, evidence). (Possible: The results *provided evidence* for a benefit).
    *   Sense 4: Make visible or noticeable. (Not applicable)
    *   Sense 5: Show in a picture (depict). (Not applicable)
    *   Sense 6: Give expression to (express, evince). (Not applicable)
    *   Sense 7: Indicate a place, direction, person, or thing. (Not applicable)
    *   Sense 8: Be or become visible or noticeable. (Not applicable)
    *   Sense 9: Indicate a certain reading (gauges/instruments). (Not applicable)
    *   Sense 10: Give evidence of, as of records. (Possible, but usually refers to documents/diaries).
    *   Sense 11: Take someone to their seats (usher). (Not applicable)
    *   Sense 12: Finish third or better in a race. (Not applicable)

    *   The sentence is: "What benefit has Alimta shown during the studies?"
    *   This is asking about the results of clinical trials.
    *   Sense 2: "establish the validity of something, as by an example, explanation or experiment" (synonyms: prove, demonstrate).
    *   Sense 3: "provide evidence for" (synonyms: testify, bear witness, prove, evidence).
    *   Comparing Sense 2 and Sense 3:
        *   Sense 2 specifically mentions "experiment," which fits "studies" perfectly. "The experiment demonstrated the instability of the compound" is very similar to "The studies showed a benefit."
        *   Sense 3 is more general ("provide evidence for").
        *   In medical literature, when a drug "shows" a benefit in a study, it is demonstrating/establishing the validity of that benefit through the experimental process.

    *   Sense 2: "establish the validity of something, as by an example, explanation or experiment"
    *   Sense 3: "provide evidence for"
    *   Looking at the examples for Sense 2: "The experiment demonstrated the instability of the compound."
    *   Looking at the examples for Sense 3: "The blood test showed that he was the father."
    *   The context "during the studies" strongly aligns with the "experiment" part of Sense 2's definition.

    *   Wait, let me re-read Sense 3: "provide evidence for". A blood test provides evidence. A clinical study provides evidence.
    *   Let me re-read Sense 2: "establish the validity of something, as by an example, explanation or experiment".
    *   In the context of "What benefit has Alimta shown during the studies?", the drug itself is the subject. "Alimta has shown [a benefit]".
    *   If Alimta (the drug) is the subject, does it "establish the validity" (Sense 2) or "provide evidence for" (Sense 3)?
    *   Actually, usually, the *study* shows the benefit, or the *results* show the benefit. Here, the drug is the subject: "What benefit has Alimta shown...?"
    *   If we say "The drug showed a benefit," it means the drug *demonstrated* a benefit.
    *   Let's look at Sense 2 again: "establish the validity of something, as by an example, explanation or experiment".
    *   Let's look at Sense 3 again: "provide evidence for".
    *   Let's look at Sense 8: "be or become visible or noticeable". (No)
    *   Let's look at Sense 4: "make visible or noticeable". (No)

    *   Sense 2: "establish the validity of something, as by an example, explanation or experiment"
    *   Sense 3: "provide evidence for"
    *   Example for Sense 2: "The experiment demonstrated the instability of the compound." (Subject is the experiment).
    *   Example for Sense 3: "The blood test showed that he was the father." (Subject is the test).
    *   In the target sentence: "What benefit has Alimta shown...?" (Subject is the drug).
    *   If the drug is the subject, "Alimta showed a benefit" means the drug *demonstrated* a benefit.
    *   Is "demonstrate" a synonym for Sense 2? Yes.
    *   Is "prove" a synonym for Sense 2? Yes.
    *   Is "prove" a synonym for Sense 3? Yes.
    *   Is "evidence" a synonym for Sense 3? Yes.

    *   Let's think about the usage "The drug showed improvement." This usually means the drug *demonstrated* improvement.
    *   Sense 2: "establish the validity of something, as by an example, explanation or experiment".
    *   Sense 3: "provide evidence for".
    *   In medical contexts, "showed a benefit" is almost always synonymous with "demonstrated a benefit."
    *   Sense 2's definition "establish the validity... by... experiment" fits the "studies" context perfectly.

    *   Sense 2: establish validity via experiment.
    *   Sense 3: provide evidence for.
    *   If the drug is the subject, it's demonstrating the benefit.
    *   Let's check Sense 2 synonyms: prove, demonstrate, establish.
    *   Let's check Sense 3 synonyms: testify, bear witness, prove, evidence.
    *   "Alimta demonstrated a benefit" (Sense 2) vs "Alimta provided evidence for a benefit" (Sense 3).
    *   "Demonstrated" feels more natural here.

    *   Wait, let me look at Sense 3 again. "The blood test showed that he was the father." The blood test is the evidence.
    *   In "What benefit has Alimta shown during the studies?", Alimta is the thing being tested. The *results* of the studies show the benefit. But the phrasing "Alimta has shown" is a common shorthand for "The use of Alimta has shown" or "Alimta has demonstrated".
    *   If we use "demonstrate" (Sense 2), it fits well.

    *   Sense 2: establish validity by experiment.
    *   Sense 3: provide evidence for.
    *   Looking at the examples again:
        *   Sense 2: "The experiment demonstrated the instability of the compound."
        *   Sense 3: "The blood test showed that he was the father."
    *   The "experiment" in Sense 2 is the *means* of showing. In the target sentence, the "studies" are the means.
    *   The "blood test" in Sense 3 is the *source* of the evidence.
    *   In "What benefit has Alimta shown during the studies?", Alimta is the subject, and the studies are the context.
    *   This is a bit tricky. Let's try to replace "shown" with the synonyms.
        *   "What benefit has Alimta demonstrated during the studies?" (Sense 2) - Very natural.
        *   "What benefit has Alimta evidenced during the studies?" (Sense 3) - Less natural.
        *   "What benefit has Alimta proven during the studies?" (Sense 2/3) - Natural.

    *   Sense 2 is specifically about establishing validity through an experiment. Clinical studies are experiments.

    *   Sense 2: establish validity via experiment.
    *   Sense 3: provide evidence for.
    *   Sense 10: give evidence of, as of records.
    *   Sense 2 seems the most precise for a clinical study context.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: study
Target surface form: studies
Context:
For the treatment of malignant pleural mesothelioma, Alimta has been studied in one main study in 456 patients who had not received chemotherapy for their disease before. The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the <t>studies</t>? Alimta increased the survival time of patients with malignant pleural mesothelioma.

Candidate senses:
1. sense_key=study%1:04:00:: | definition=a detailed critical inspection | synonyms=survey
2. sense_key=study%1:09:03:: | definition=applying the mind to learning and understanding a subject (especially by reading) | synonyms=work | examples=mastering a second language requires a lot of work; no schools offer graduate study in interior design
3. sense_key=study%1:10:00:: | definition=a written document describing the findings of some individual or group | synonyms=report, written report | examples=this accords with the recent study by Hill and Dale
4. sense_key=study%1:09:04:: | definition=a state of deep mental absorption | examples=she is in a deep study
5. sense_key=study%1:06:00:: | definition=a room used for reading and writing and studying | examples=he knocked lightly on the closed door of the study
6. sense_key=study%1:09:02:: | definition=a branch of knowledge | synonyms=discipline, subject, subject area, subject field, field, field of study | examples=in what discipline is his doctorate?; teachers should be well trained in their subject
7. sense_key=study%1:06:01:: | definition=preliminary drawing for later elaboration | synonyms=sketch | examples=he made several studies before starting to paint
8. sense_key=study%1:09:01:: | definition=attentive consideration and meditation | synonyms=cogitation | examples=after much cogitation he rejected the offer
9. sense_key=study%1:18:00:: | definition=someone who memorizes quickly and easily (as the lines for a part in a play) | examples=he is a quick study
10. sense_key=study%1:10:01:: | definition=a composition intended to develop one aspect of the performer's technique | examples=a study in spiccato bowing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `study`
    *   Target surface form: `studies`
    *   Context: The text describes clinical trials for a drug called Alimta. It mentions "one main study in 456 patients", "one study involving 571 patients", and "a study involving 1,725 patients". It then asks, "What benefit has Alimta shown during the <t>studies</t>?"
    *   The word "studies" refers back to these clinical trials/investigations.

    *   Sense 1: `study%1:04:00` - a detailed critical inspection (synonym: survey).
    *   Sense 2: `study%1:09:03` - applying the mind to learning and understanding a subject (synonym: work).
    *   Sense 3: `study%1:10:00` - a written document describing the findings of some individual or group (synonyms: report, written report).
    *   Sense 4: `study%1:09:04` - a state of deep mental absorption.
    *   Sense 5: `study%1:06:00` - a room used for reading and writing and studying.
    *   Sense 6: `study%1:09:02` - a branch of knowledge (synonym: discipline).
    *   Sense 7: `study%1:06:01` - preliminary drawing for later elaboration (synonym: sketch).
    *   Sense 8: `study%1:09:01` - attentive consideration and meditation (synonym: cogitation).
    *   Sense 9: `study%1:18:00` - someone who memorizes quickly and easily.
    *   Sense 10: `study%1:10:01` - a composition intended to develop one aspect of the performer's technique.

    *   The context describes clinical trials. A clinical trial is a systematic investigation/inspection to evaluate a drug.
    *   Sense 1 ("a detailed critical inspection") fits the process of the clinical trial.
    *   Sense 3 ("a written document describing the findings") fits the report of the trial.
    *   In medical contexts, "a study" often refers to both the investigation itself and the resulting report.
    *   Looking at the phrasing: "Alimta has been studied in one main study in 456 patients", "one study involving 571 patients", "a study involving 1,725 patients". These refer to the *investigations* (the trials).
    *   "What benefit has Alimta shown during the studies?" refers to the period/process of the investigations.
    *   Comparing Sense 1 and Sense 3:
        *   Sense 1: "a detailed critical inspection" (survey).
        *   Sense 3: "a written document describing the findings" (report).
    *   While the results are written in a report, the "benefit shown during the studies" refers to the actual trials/investigations conducted on the patients.
    *   Wait, let's re-evaluate Sense 1 vs Sense 3. In many WordNet-based WSD tasks, "study" in the sense of a scientific research project is often mapped to the "detailed critical inspection" or "written report" depending on the specific nuance.
    *   Let's look at Sense 1 again: "a detailed critical inspection".
    *   Let's look at Sense 3 again: "a written document describing the findings".
    *   The sentence "What benefit has Alimta shown during the studies?" suggests the process/investigation.
    *   However, in common usage, "a study" in medicine is the research project.
    *   Let's check if there's a better fit.
    *   Sense 1 (inspection/survey) is closer to the act of investigating.
    *   Sense 3 (report) is the document.
    *   Usually, "clinical study" = "clinical trial" = "detailed critical inspection" of a drug's effect.

    *   Sense 1: `study%1:04:00` (detailed critical inspection)
    *   Sense 3: `study%1:10:00` (written document)
    *   The context says "Alimta has been studied in one main study in 456 patients". This refers to the trial.
    *   "What benefit has Alimta shown during the studies?"
    *   If it were the document, it would be "in the studies" (meaning in the reports). "During the studies" strongly implies the duration of the investigation.
    *   Therefore, Sense 1 is a better fit than Sense 3.

    *   Wait, let me double-check WordNet's typical mapping for "scientific study".
    *   Often, "study" as in "a research study" is mapped to `study%1:04:00` (detailed critical inspection).
    *   Let's re-read Sense 1: "a detailed critical inspection".
    *   Let's re-read Sense 3: "a written document describing the findings".
    *   "During the studies" -> The time period of the investigation.
    *   Sense 1 fits "investigation" better than Sense 3 fits "document".

    *   Sense 1: detailed critical inspection.
    *   Sense 3: written document.
    *   Context: "one main study in 456 patients", "one study involving 571 patients", "a study involving 1,725 patients".
    *   These are clinical trials. A clinical trial is an inspection/investigation.
    *   "During the studies" = during the trials.
    *   Sense 1 is the most appropriate.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: increase
Target surface form: increased
Context:
The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta <t>increased</t> the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone.

Candidate senses:
1. sense_key=increase%2:30:00:: | definition=become bigger or greater in amount | examples=The amount of work increased
2. sense_key=increase%2:30:02:: | definition=make bigger or more | examples=The boss finally increased her salary; The university increased the number of students it admitted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `increase`
    *   Target surface form: `increased`
    *   Context: "Alimta <t>increased</t> the survival time of patients with malignant pleural mesothelioma."
    *   Candidate senses:
        1.  `increase%2:30:00::` (intransitive): become bigger or greater in amount.
        2.  `increase%2:30:02::` (transitive): make bigger or more.

    *   Sentence: "Alimta increased the survival time of patients..."
    *   Subject: "Alimta" (the drug)
    *   Verb: "increased"
    *   Object: "the survival time of patients"

    *   Sense 1 is intransitive (the subject itself becomes bigger). Example: "The amount of work increased."
    *   Sense 2 is transitive (the subject makes something else bigger). Example: "The boss finally increased her salary."

    *   In the context, "Alimta" (the subject) is acting upon "the survival time" (the object) to make it longer/greater.
    *   This matches the transitive usage described in Sense 2.

    *   Sense 2 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survival
Target surface form: survival
Context:
The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the <t>survival</t> time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone.

Candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
3. sense_key=survival%1:04:00:: | definition=something that survives

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `survival`
    *   Target surface form: `survival`
    *   Context: "Alimta increased the <t>survival</t> time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months..."
    *   Candidate senses:
        1.  `survival%1:26:00::`: a state of surviving; remaining alive (synonym: endurance)
        2.  `survival%1:22:00::`: a natural process resulting in the evolution of organisms best adapted to the environment (synonyms: survival of the fittest, natural selection, selection)
        3.  `survival%1:04:00::`: something that survives

    *   The context discusses medical studies on cancer treatments (Alimta, cisplatin, docetaxel, gemcitabine).
    *   The specific phrase is "increased the survival time of patients".
    *   This refers to the duration for which patients remained alive.

    *   Sense 1: "a state of surviving; remaining alive". This fits perfectly with "survival time" (the duration of the state of remaining alive).
    *   Sense 2: "a natural process resulting in the evolution of organisms..." (Natural selection). This is a biological/evolutionary concept and does not fit the medical context of patient survival.
    *   Sense 3: "something that survives". This refers to an entity (e.g., "the survival of a species" or "a survival from the 18th century"). The context is about the *time* spent alive, not a specific entity that survived.

    *   Sense 1 is the only one that describes the state of remaining alive, which is exactly what "survival time" refers to in a clinical trial.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: time
Target surface form: time
Context:
The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival <t>time</t> of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone.

Candidate senses:
1. sense_key=time%1:11:00:: | definition=an instance or single occasion for some event | synonyms=clip | examples=this time he succeeded; he called four times
2. sense_key=time%1:28:05:: | definition=a period of time considered as a resource under your control and sufficient to accomplish something | examples=take time to smell the roses; I didn't have time to finish
3. sense_key=time%1:28:00:: | definition=an indefinite period (usually marked by specific attributes or activities) | examples=he waited a long time; the time of year for planting
4. sense_key=time%1:28:06:: | definition=a suitable moment | examples=it is time to go
5. sense_key=time%1:03:00:: | definition=the continuum of experience in which events pass from the future through the present to the past
6. sense_key=time%1:11:01:: | definition=a person's experience on a particular occasion | examples=he had a time holding back the tears; they had a good time together
7. sense_key=time%1:28:03:: | definition=a reading of a point in time as given by a clock | synonyms=clock time | examples=do you know what time it is?; the time is 10 o'clock
8. sense_key=time%1:28:04:: | definition=the fourth coordinate that is required (along with three spatial dimensions) to specify a physical event | synonyms=fourth dimension
9. sense_key=time%1:07:01:: | definition=rhythm as given by division into parts of equal duration | synonyms=meter, metre
10. sense_key=time%1:28:01:: | definition=the period of time a prisoner is imprisoned | synonyms=prison term, sentence | examples=he served a prison term of 15 months; his sentence was 5 to 10 years

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `time`
    *   Target surface form: `time`
    *   Context: "Alimta increased the survival <t>time</t> of patients with malignant pleural mesothelioma."
    *   Surrounding context: "Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone."

    *   Sense 1: an instance or single occasion (e.g., "this time he succeeded").
    *   Sense 2: a period of time as a resource (e.g., "take time to smell the roses").
    *   Sense 3: an indefinite period (usually marked by specific attributes or activities) (e.g., "he waited a long time").
    *   Sense 4: a suitable moment (e.g., "it is time to go").
    *   Sense 5: the continuum of experience (the general concept of time).
    *   Sense 6: a person's experience on a particular occasion (e.g., "they had a good time").
    *   Sense 7: a reading of a point in time as given by a clock (e.g., "what time is it?").
    *   Sense 8: the fourth coordinate (physics).
    *   Sense 9: rhythm/meter.
    *   Sense 10: prison term.

    *   The phrase is "survival time".
    *   "Survival time" refers to the duration of time a patient survives after a diagnosis or treatment.
    *   Looking at the candidate senses:
        *   Sense 1 (instance) - No.
        *   Sense 2 (resource) - No.
        *   Sense 3 (an indefinite period / period marked by specific attributes) - This fits best. "Survival time" is a period of time marked by the attribute of survival.
        *   Sense 4 (suitable moment) - No.
        *   Sense 5 (continuum) - No.
        *   Sense 6 (experience) - No.
        *   Sense 7 (clock reading) - No.
        *   Sense 8 (fourth dimension) - No.
        *   Sense 9 (rhythm) - No.
        *   Sense 10 (prison term) - No.

    *   Sense 3: "an indefinite period (usually marked by specific attributes or activities)".
    *   Example: "he waited a long time".
    *   In "survival time", the "period" is the duration of survival. This is a standard way WordNet categorizes durations of specific states or activities.

    *   Is there a better sense?
    *   Sense 5 is the abstract concept.
    *   Sense 3 is a specific duration/period.
    *   "Survival time" is a duration (12.1 months). Sense 3 is the most appropriate for a duration of time.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The effects of Alimta in combination with cisplatin were compared with those of cisplatin alone. For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of <t>patients</t> with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text discussing the effects of Alimta and cisplatin on people with non-small cell lung cancer and malignant pleural mesothelioma.
    *   Specific sentence: "Alimta increased the survival time of <t>patients</t> with malignant pleural mesothelioma."

    *   Sense 1: `patient%1:18:00::` | definition: "a person who requires medical care" | examples: "the number of emergency patients has grown rapidly"
    *   Sense 2: `patient%1:10:00::` | definition: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" | synonyms: "affected role, patient role"

    *   The context is clearly medical.
    *   The word "patients" refers to people with lung cancer or mesothelioma who are receiving treatment (Alimta, cisplatin).
    *   This matches Sense 1 ("a person who requires medical care").
    *   Sense 2 is a linguistic term (semantic role), which is completely irrelevant to the medical context.

    *   Sense 1 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: Patients
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. <t>Patients</t> receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `Patients`
    *   Context: A medical text discussing clinical trials for Alimta (an anticancer medicine) for non-small cell lung cancer and malignant pleural mesothelioma. The sentence is: "<t>Patients</t> receiving Alimta and cisplatin survived for an average of 12.1 months..."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent... (linguistic term).

    *   The context is clearly medical. It discusses cancer treatments, chemotherapy, survival times, and people receiving medication.
    *   "Patients receiving Alimta and cisplatin" refers to the people being treated in the study.

    *   Sense 1: "a person who requires medical care" fits perfectly.
    *   Sense 2: "the semantic role of an entity..." is a linguistic term used in grammar/semantics. This is completely irrelevant to the context.

    *   The correct sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survive
Target surface form: survived
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin <t>survived</t> for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=survive%2:42:01:: | definition=continue to live through hardship or adversity | synonyms=last, live, live on, go, endure, hold up | examples=We went without water and food for 3 days; These superstitions survive in the backwaters of America
2. sense_key=survive%2:42:02:: | definition=continue in existence after (an adversity, etc.) | synonyms=pull through, pull round, come through, make it | examples=He survived the cancer against all odds
3. sense_key=survive%2:42:00:: | definition=support oneself | synonyms=exist, live, subsist | examples=he could barely exist on such a low wage; Can you live on $2000 a month in New York City?
4. sense_key=survive%2:42:03:: | definition=live longer than | synonyms=outlive, outlast | examples=She outlived her husband by many years

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `survive`
    *   Target surface form: `survived`
    *   Context: "Patients receiving Alimta and cisplatin <t>survived</t> for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone."
    *   Contextual clues: The text discusses cancer treatment, "survival time," and the duration patients lived after treatment.

    *   Sense 1: `continue to live through hardship or adversity` (e.g., "survive in the backwaters", "went without water"). Focuses on enduring a difficult situation.
    *   Sense 2: `continue in existence after (an adversity, etc.)` (e.g., "survived the cancer"). Focuses on the outcome of surviving a specific event/disease.
    *   Sense 3: `support oneself` (e.g., "live on $2000 a month"). Focuses on financial/material subsistence.
    *   Sense 4: `live longer than` (e.g., "outlived her husband"). Focuses on relative longevity.

    *   The sentence says "survived for an average of 12.1 months".
    *   This refers to the length of time they continued to live.
    *   Sense 1 ("continue to live through hardship or adversity") fits the general idea of living despite a disease.
    *   Sense 2 ("continue in existence after (an adversity, etc.)") usually implies surviving the *entirety* of the event (e.g., "He survived the cancer" means he is now cancer-free or lived through the crisis). In this context, they didn't necessarily "survive the cancer" (since they died after 12.1 months), but they "survived" (continued to live) for a certain period.
    *   Sense 3 is irrelevant (financial).
    *   Sense 4 is irrelevant (not comparing one person's lifespan to another specific person's).

    *   Sense 1: "continue to live through hardship or adversity". Synonyms: last, live, live on, go, endure.
    *   Sense 2: "continue in existence after (an adversity, etc.)". Synonyms: pull through, pull round, come through, make it.
    *   In medical literature, "overall survival" or "patients survived for X months" refers to the duration of life.
    *   Looking at Sense 1 again: "continue to live through hardship or adversity". The cancer is the adversity.
    *   Looking at Sense 2 again: "continue in existence after (an adversity, etc.)". This usually means surviving the *event* (recovery).
    *   The phrase "survived for an average of 12.1 months" describes the act of continuing to live.

    *   Sense 1: "continue to live through hardship or adversity" (last, live, live on).
    *   Sense 2: "continue in existence after (an adversity, etc.)" (pull through, make it).
    *   If a patient "survived for 12 months," they didn't "pull through" (Sense 2) the cancer; they lived for 12 months *despite* it.
    *   Therefore, Sense 1 is the most accurate description of "continuing to live" during a period of adversity.

    *   Wait, let me re-read Sense 1 and 2.
    *   Sense 1: "continue to live through hardship or adversity"
    *   Sense 2: "continue in existence after (an adversity, etc.)"
    *   Example for Sense 1: "We went without water and food for 3 days".
    *   Example for Sense 2: "He survived the cancer against all odds".
    *   In the target sentence: "Patients... survived for an average of 12.1 months".
    *   This is describing the *duration* of their life.
    *   Sense 1's synonyms include "live" and "last". "Patients lived for an average of 12.1 months."
    *   Sense 2's synonyms include "pull through" and "make it". "Patients pulled through for an average of 12.1 months" doesn't make sense.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: average
Target surface form: average
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an <t>average</t> of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=average%1:09:00:: | definition=a statistic describing the location of a distribution | synonyms=norm | examples=it set the norm for American homes
2. sense_key=average%1:24:00:: | definition=(sports) the ratio of successful performances to opportunities
3. sense_key=average%1:09:01:: | definition=an intermediate scale value regarded as normal or usual | examples=he is about average in height; the snowfall this month is below average

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `average`
    *   Target surface form: `average`
    *   Context: "Patients receiving Alimta and cisplatin survived for an <t>average</t> of 12.1 months, compared with 9.3 months in those receiving cisplatin alone."
    *   Candidate senses:
        1.  `average%1:09:00::`: a statistic describing the location of a distribution (synonym: norm).
        2.  `average%1:24:00::`: (sports) the ratio of successful performances to opportunities.
        3.  `average%1:09:01::`: an intermediate scale value regarded as normal or usual.

    *   The sentence describes a clinical study result: "survived for an average of 12.1 months".
    *   In this context, "average" refers to a calculated statistical value (likely the mean or median survival time) derived from a group of patients.

    *   Sense 1: "a statistic describing the location of a distribution". This fits perfectly. The mean survival time is a statistic describing the central tendency (location) of the survival distribution of the patient group.
    *   Sense 2: "(sports) the ratio of successful performances to opportunities". This is clearly incorrect.
    *   Sense 3: "an intermediate scale value regarded as normal or usual". This refers to being "average" in height or "below average" snowfall (meaning typical/ordinary). While related, the context here is a specific statistical calculation from a study, not a general description of being "ordinary".

    *   The context is a medical study reporting a specific number (12.1 months) as the "average". This is a statistical measure.
    *   Sense 1 is the statistical definition.
    *   Sense 3 is the "ordinary/typical" definition.
    *   In "survived for an average of 12.1 months", "average" is used as a noun referring to the mean/median value.

    *   Sense 1: "a statistic describing the location of a distribution" -> Fits "average of 12.1 months".
    *   Sense 3: "an intermediate scale value regarded as normal or usual" -> Fits "he is about average in height".

    The usage in the text is clearly the statistical one.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 <t>months</t>, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `month`
    *   Target surface form: `months`
    *   Context: "Patients receiving Alimta and cisplatin survived for an average of 12.1 <t>months</t>, compared with 9.3 months in those receiving cisplatin alone."
    *   Candidate senses:
        1.  `month%1:28:01::`: one of the twelve divisions of the calendar year (calendar month).
        2.  `month%1:28:00::`: a time unit of approximately 30 days.

    *   The context refers to "an average of 12.1 months" and "9.3 months".
    *   These are measurements of duration (survival time), not specific calendar months (like January or February).
    *   "12.1 months" is a quantity of time, not a specific division of a calendar year.

    *   Sense 1 (calendar month) refers to the named months of the year.
    *   Sense 2 (time unit) refers to a duration of approximately 30 days.

    *   The usage "12.1 months" clearly indicates a duration/time unit.

    *   Sense index: 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: compare
Target surface form: compared
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, <t>compared</t> with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=compare%2:31:00:: | definition=examine and note the similarities or differences of | examples=John compared his haircut to his friend's; We compared notes after we had both seen the movie
2. sense_key=compare%2:42:00:: | definition=be comparable | examples=This car does not compare with our line of Mercedes
3. sense_key=compare%2:31:01:: | definition=consider or describe as similar, equal, or analogous | synonyms=liken, equate | examples=We can compare the Han dynasty to the Romans; You cannot equate success in financial matters with greed
4. sense_key=compare%2:32:00:: | definition=to form the comparative or superlative form on an adjective or adverb

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `compare`
    *   Target surface form: `compared`
    *   Context: "Patients receiving Alimta and cisplatin survived for an average of 12.1 months, <t>compared</t> with 9.3 months in those receiving cisplatin alone."

    *   Sense 1: `examine and note the similarities or differences of` (e.g., "John compared his haircut to his friend's"). This is the active process of analyzing two things.
    *   Sense 2: `be comparable` (e.g., "This car does not compare with our line of Mercedes"). This refers to the quality of being similar or equal in value/quality.
    *   Sense 3: `consider or describe as similar, equal, or analogous` (synonyms: liken, equate).
    *   Sense 4: `to form the comparative or superlative form on an adjective or adverb`. (Grammatical sense).

    *   The sentence is: "Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone."
    *   Here, "compared with" is used to contrast two sets of data (12.1 months vs 9.3 months).
    *   It's not about "forming a comparative" (Sense 4).
    *   It's not about "being comparable" in the sense of quality/value (Sense 2).
    *   It's not exactly "likening" or "equating" (Sense 3).
    *   It is the act of examining/noting the difference between two values.

    *   Sense 1: "examine and note the similarities or differences of".
    *   In the context of scientific reporting, "compared with" is a standard way to present a contrast between two groups to highlight a difference. This fits the "note the similarities or differences of" part of Sense 1.

    *   Sense 1: "examine and note the similarities or differences of" -> Fits perfectly.
    *   Sense 2: "be comparable" -> Usually used as "doesn't compare" or "compares well". Not the case here.
    *   Sense 3: "consider or describe as similar, equal, or analogous" -> This is more about metaphors or analogies (likening).
    *   Sense 4: Grammatical. Not applicable.

    *   The phrase "compared with" in this context is a participial phrase used to introduce a contrast. The underlying meaning is that the author is noting the difference between the two survival times. This aligns with Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 <t>months</t> in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `month`
    *   Target surface form: `months`
    *   Context: "...Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 <t>months</t> in those receiving cisplatin alone."
    *   Candidate senses:
        1.  `month%1:28:01::`: one of the twelve divisions of the calendar year (calendar month).
        2.  `month%1:28:00::`: a time unit of approximately 30 days.

    *   The context refers to "12.1 months" and "9.3 months".
    *   These are measurements of survival time (duration).
    *   "12.1 months" is not referring to a specific calendar month (like January or February) or a specific division of a specific year. It is referring to a quantity of time.

    *   Sense 1: "one of the twelve divisions of the calendar year" (e.g., "last month"). This is a specific calendar division.
    *   Sense 2: "a time unit of approximately 30 days". This is a measure of duration.

    *   The usage "9.3 months" clearly indicates a duration of time, not a specific calendar month. Therefore, Sense 2 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the <t>treatment</t> of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "treatment"
    *   Context: "In the <t>treatment</t> of patients with non-small cell lung cancer, Alimta was as effective as the comparators."
    *   Surrounding context: Discussion of anticancer medicines (Alimta, gemcitabine, cisplatin, docetaxel), chemotherapy, survival time, and patients with lung cancer.

    *   Sense 1: "care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury)" (Synonym: intervention).
    *   Sense 2: "the management of someone or something" (Synonym: handling; Examples: handling of prisoners, treatment of water sewage).
    *   Sense 3: "a manner of dealing with something artistically" (Example: treatment of space in architecture).
    *   Sense 4: "an extended communication (often interactive) dealing with some particular topic" (Synonyms: discussion, discourse).

    *   The context is explicitly medical ("patients with non-small cell lung cancer", "anticancer medicine", "chemotherapy").
    *   "Treatment" here refers to the medical care/procedure provided to the patients to treat their cancer.
    *   This aligns perfectly with Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of <t>patients</t> with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text discussing clinical trials for Alimta (an anticancer medicine) involving people with lung cancer and malignant pleural mesothelioma.
    *   Specific sentence: "In the treatment of <t>patients</t> with non-small cell lung cancer, Alimta was as effective as the comparators."

    *   Sense 1: `patient%1:18:00::` | definition: "a person who requires medical care" | examples: "the number of emergency patients has grown rapidly"
    *   Sense 2: `patient%1:10:00::` | definition: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" | synonyms: "affected role, patient role"

    *   The context is clearly medical.
    *   "patients with non-small cell lung cancer" refers to people receiving medical treatment for a disease.
    *   This matches Sense 1 ("a person who requires medical care").
    *   Sense 2 is a linguistic term (semantic role), which is completely irrelevant to the context of cancer treatment.

    *   Sense 1 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small <t>cell</t> lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "cell"
    *   Target surface form: "cell"
    *   Context: "...In the treatment of patients with non-small <t>cell</t> lung cancer, Alimta was as effective as the comparators..."
    *   Candidate senses:
        1.  Small compartment (honeycomb).
        2.  (Biology) Basic structural and functional unit of all organisms.
        3.  Electric current device.
        4.  Political movement unit (cadre).
        5.  Mobile phone.
        6.  Monk/nun room.
        7.  Prisoner room.

    *   The phrase is "non-small cell lung cancer".
    *   "Lung cancer" refers to a disease of the lungs.
    *   "Non-small cell" describes the type of cancer, specifically referring to the size and type of the cancer cells (biological units).

    *   Sense 2: "(biology) the basic structural and functional unit of all organisms..." fits perfectly with the medical context of cancer (which is a disease of cells).

    *   Sense 1 (compartment), 3 (electric), 4 (political), 5 (phone), 6 (monk), 7 (prison) are all irrelevant to lung cancer.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: effective
Target surface form: effective
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as <t>effective</t> as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=effective%3:00:00:: | definition=producing or capable of producing an intended result or having a striking effect; -LewisMumford | synonyms=effectual, efficacious | examples=an air-cooled motor was more effective than a witch's broomstick for rapid long-distance transportation; effective teaching methods
2. sense_key=effective%5:00:00:competent:00 | definition=able to accomplish a purpose; functioning effectively; -G.B.Shaw | synonyms=efficient | examples=people who will do nothing unless they get something out of it for themselves are often highly effective persons...; effective personnel
3. sense_key=effective%5:00:00:efficacious:00 | definition=works well as a means or remedy | examples=an effective reprimand; a lotion that is effective in cases of prickly heat
4. sense_key=effective%5:00:00:operative:00 | definition=exerting force or influence | synonyms=good, in effect, in force | examples=the law is effective immediately; a warranty good for two years
5. sense_key=effective%5:00:00:actual:00 | definition=existing in fact; not theoretical; real | examples=a decline in the effective demand; confused increased equipment and expenditure with the quantity of effective work done
6. sense_key=effective%5:00:00:operational:00 | definition=ready for service | examples=the fort was held by about 100 effective soldiers

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target word: "effective"
    *   Context: "In the treatment of patients with non-small cell lung cancer, Alimta was as <t>effective</t> as the comparators."
    *   Surrounding context: The text discusses clinical studies of a medicine (Alimta) compared to others (gemcitabine, cisplatin, docetaxel). It mentions "the main measure of effectiveness was how long the patients survived."

    *   Sense 1: producing or capable of producing an intended result or having a striking effect (general). Synonyms: effectual, efficacious.
    *   Sense 2: able to accomplish a purpose; functioning effectively (often applied to people/personnel). Synonym: efficient.
    *   Sense 3: works well as a means or remedy (specifically mentions "remedy" and "lotion").
    *   Sense 4: exerting force or influence (laws, warranties).
    *   Sense 5: existing in fact; not theoretical; real (effective demand).
    *   Sense 6: ready for service (soldiers).

    *   The context is medical treatment (Alimta, a medicine).
    *   The word "effective" refers to how well the medicine worked as a remedy/treatment for lung cancer.
    *   Sense 3 specifically mentions "works well as a means or remedy" and gives an example of a "lotion that is effective in cases of prickly heat." This aligns perfectly with a medicine's efficacy in treating a disease.
    *   Sense 1 is a broader version of Sense 3.
    *   Sense 2 is more about efficiency/competence.
    *   Senses 4, 5, and 6 are completely irrelevant.

    *   Sense 1: General "producing an intended result."
    *   Sense 3: Specific to "means or remedy."
    *   Since Alimta is a medicine (a remedy), Sense 3 is the most precise fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In <t>patients</t> who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text discussing the effectiveness of a drug (Alimta) on survival times for people with various cancers (malignant pleural mesothelioma, non-small cell lung cancer).
    *   Target sentence: "In <t>patients</t> who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel."

    *   Sense 1: `patient%1:18:00::` | definition: "a person who requires medical care" | examples: "the number of emergency patients has grown rapidly"
    *   Sense 2: `patient%1:10:00::` | definition: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" | synonyms: "affected role, patient role"

    *   The context is clearly medical.
    *   The "patients" mentioned are people receiving chemotherapy and cancer treatments.
    *   This aligns perfectly with Sense 1 ("a person who requires medical care").
    *   Sense 2 is a linguistic term (semantic role), which is completely irrelevant to the context of cancer treatment and survival rates.

    *   Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the <t>past</t>, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `past`
    *   Target surface form: `past`
    *   Context: "In patients who had received chemotherapy in the <t>past</t>, the average survival time was 8.3 months with Alimta..."
    *   Candidate senses:
        1.  `past%1:28:00::`: the time that has elapsed (synonyms: past times, yesteryear; example: forget the past).
        2.  `past%1:28:01::`: an earlier period in someone's life (especially one that they have reason to keep secret) (example: reporters dug into the candidate's past).
        3.  `past%1:10:00::`: a verb tense that expresses actions or states in the past (synonyms: past tense).

    *   The phrase is "in the past".
    *   It refers to a time before the current study/treatment period.
    *   It describes patients who had previously received chemotherapy.

    *   Sense 3 (verb tense) is completely irrelevant.
    *   Sense 2 (earlier period in life, often secret) is too specific and doesn't fit the medical context of previous treatment.
    *   Sense 1 (the time that has elapsed) fits best. "In the past" is a common idiom meaning "at a previous time" or "during the time that has elapsed".

    *   Sense 1: "the time that has elapsed". This is the general meaning of "the past" as a period of time before now.

    *   The target word "past" in "in the past" refers to the time before the current point of reference. This aligns with sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: average
Target surface form: average
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the <t>average</t> survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=average%5:00:02:normal:01 | definition=approximating the statistical norm or average or expected value | synonyms=mean | examples=the average income in New England is below that of the nation; of average height for his age
2. sense_key=average%5:00:00:common:01 | definition=lacking special distinction, rank, or status; commonly encountered | synonyms=ordinary | examples=average people; the ordinary (or common) man in the street
3. sense_key=average%5:00:00:ordinary:00 | definition=lacking exceptional quality or ability | synonyms=fair, mediocre, middling | examples=a novel of average merit; only a fair performance of the sonata
4. sense_key=average%5:00:00:moderate:00 | definition=around the middle of a scale of evaluation | synonyms=intermediate, medium | examples=an orange of average size; intermediate capacity
5. sense_key=average%5:00:03:normal:01 | definition=relating to or constituting the most frequent value in a distribution | synonyms=modal | examples=the modal age at which American novelists reach their peak is 30
6. sense_key=average%5:00:01:normal:01 | definition=relating to or constituting the middle value of an ordered set of values (or the average of the middle two in a set with an even number of values) | synonyms=median | examples=the median value of 17, 20, and 36 is 20; the median income for the year was $15,000

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `average`
    *   Target surface form: `average`
    *   Context: "In patients who had received chemotherapy in the past, the <t>average</t> survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel."
    *   Usage: "average survival time"

    *   Sense 1: `average%5:00:02:normal:01` - approximating the statistical norm or average or expected value (synonym: mean). Example: "the average income in New England".
    *   Sense 2: `average%5:00:00:common:01` - lacking special distinction, rank, or status; commonly encountered (synonym: ordinary). Example: "average people".
    *   Sense 3: `average%5:00:00:ordinary:00` - lacking exceptional quality or ability (synonym: fair, mediocre). Example: "a novel of average merit".
    *   Sense 4: `average%5:00:00:moderate:00` - around the middle of a scale of evaluation (synonym: intermediate, medium). Example: "an orange of average size".
    *   Sense 5: `average%5:00:03:normal:01` - relating to or constituting the most frequent value in a distribution (synonym: modal). Example: "the modal age...".
    *   Sense 6: `average%5:00:01:normal:01` - relating to or constituting the middle value of an ordered set of values (synonym: median). Example: "the median value...".

    *   The context discusses clinical study results: "survival time was 8.3 months".
    *   In medical studies, "average survival time" typically refers to the mean (the sum of survival times divided by the number of patients).
    *   Sense 1 specifically mentions "approximating the statistical norm or average or expected value" and lists "mean" as a synonym.
    *   Sense 5 is "modal" (most frequent).
    *   Sense 6 is "median" (middle value).
    *   While "average" can sometimes be used loosely for median or mode, in the context of reporting survival times in a clinical trial summary, it almost always refers to the mean (Sense 1).

    *   Sense 1: Mean/Statistical norm. (Fits perfectly)
    *   Sense 2: Ordinary people. (Incorrect)
    *   Sense 3: Mediocre quality. (Incorrect)
    *   Sense 4: Medium size. (Incorrect)
    *   Sense 5: Modal. (Less likely than mean)
    *   Sense 6: Median. (Less likely than mean)

    *   The phrase "average survival time" is a standard way to describe the mean survival time in a population.

    *   Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survival
Target surface form: survival
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average <t>survival</t> time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
3. sense_key=survival%1:04:00:: | definition=something that survives

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "survival"
    *   Target surface form: "survival"
    *   Context: "In patients who had received chemotherapy in the past, the average <t>survival</t> time was 8.3 months with Alimta, compared with 7.9 months with docetaxel."
    *   Candidate senses:
        1.  `survival%1:26:00::`: a state of surviving; remaining alive (synonym: endurance)
        2.  `survival%1:22:00::`: a natural process resulting in the evolution of organisms best adapted to the environment (synonyms: survival of the fittest, natural selection, selection)
        3.  `survival%1:04:00::`: something that survives

    *   The context discusses medical studies on the effectiveness of a drug (Alimta).
    *   It mentions "how long the patients survived," "increased the survival time," and "the average survival time was 8.3 months."
    *   In this context, "survival" refers to the state of remaining alive after a diagnosis or treatment.

    *   Sense 1: "a state of surviving; remaining alive". This fits perfectly. "Survival time" is the duration of the state of remaining alive.
    *   Sense 2: "a natural process resulting in the evolution of organisms...". This is about Darwinian evolution. Not applicable.
    *   Sense 3: "something that survives". This refers to an object or person that has survived (e.g., "the only survival of a lost civilization"). Not applicable.

    *   The best fit is Sense 1.