[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: every
Target surface form: every
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once <t>every</t> three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=every%5:00:00:all:00 | definition=(used of count nouns) each and all of the members of a group considered singly and without exception | examples=every person is mortal; every party is welcome
2. sense_key=every%5:00:02:all:00 | definition=each and all of a series of entities or intervals as specified | examples=every third seat; every two hours

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "every"
    *   Target surface form: "every"
    *   Context: "It is given once <t>every</t> three weeks as an intravenous infusion lasting 10 minutes."
    *   Candidate senses:
        1.  `every%5:00:00:all:00`: (used of count nouns) each and all of the members of a group considered singly and without exception. (Example: "every person is mortal")
        2.  `every%5:00:02:all:00`: each and all of a series of entities or intervals as specified. (Example: "every third seat; every two hours")

    *   The phrase is "every three weeks".
    *   "Three weeks" is a time interval.
    *   The sentence describes the frequency of administration (once every three weeks).

    *   Sense 1 refers to members of a group considered singly (e.g., every person).
    *   Sense 2 refers to a series of entities or *intervals* as specified (e.g., every two hours).

    *   "Every three weeks" fits perfectly with "each and all of a series of... intervals as specified".

    *   Sense 2 is the correct match.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: week
Target surface form: weeks
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three <t>weeks</t> as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=week%1:28:00:: | definition=any period of seven consecutive days | synonyms=hebdomad | examples=it rained for a week
2. sense_key=week%1:28:01:: | definition=hours or days of work in a calendar week | synonyms=workweek | examples=they worked a 40-hour week
3. sense_key=week%1:28:02:: | definition=a period of seven consecutive days starting on Sunday | synonyms=calendar week

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

finish_reason: stop

content:
```json
{"sense_index": 1}
```

role: assistant

reasoning_content:
*   Target lemma: `week`
    *   Target surface form: `weeks`
    *   Context: "It is given once every three <t>weeks</t> as an intravenous infusion lasting 10 minutes."
    *   Candidate senses:
        1.  `week%1:28:00::`: any period of seven consecutive days.
        2.  `week%1:28:01::`: hours or days of work in a calendar week (workweek).
        3.  `week%1:28:02::`: a period of seven consecutive days starting on Sunday (calendar week).

    *   The sentence describes a medical dosing schedule: "once every three weeks".
    *   This refers to a duration of time (3 * 7 days = 21 days).
    *   It does not refer to a workweek (sense 2).
    *   It does not specifically require the period to start on a Sunday (sense 3). It simply means a period of 21 days.

    *   Sense 1: "any period of seven consecutive days". This fits perfectly for a dosing interval.
    *   Sense 2: "hours or days of work". Incorrect.
    *   Sense 3: "starting on Sunday". Too specific. Medical dosing is based on the interval, not the calendar start day.

    *   Sense 1 is the most general and accurate description of a 7-day period used for counting intervals.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous <t>infusion</t> lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
2. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)
3. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)
4. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "infusion"
    *   Target surface form: "infusion"
    *   Context: "It is given once every three weeks as an intravenous infusion lasting 10 minutes."
    *   Candidate senses:
        1.  `infusion%1:27:00::`: a solution obtained by steeping or soaking a substance (usually in water) (e.g., tea).
        2.  `infusion%1:22:00::`: the process of extracting certain active properties by steeping or soaking.
        3.  `infusion%1:04:00::`: (medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues.
        4.  `infusion%1:04:01::`: the act of infusing or introducing a certain modifying element or quality (e.g., new talent).

    *   The context mentions "Alimta" (a medicine), "intravenous infusion", and "lasting 10 minutes".
    *   "Intravenous" means "within a vein".
    *   This clearly refers to the medical administration of a drug into a vein.

    *   Sense 1: Steeping/soaking (like tea). Incorrect.
    *   Sense 2: Process of extracting properties by steeping. Incorrect.
    *   Sense 3: (medicine) passive introduction of a substance into a vein. Correct.
    *   Sense 4: Introducing a quality/element (metaphorical). Incorrect.

    *   The best fit is sense 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: last
Target surface form: lasting
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion <t>lasting</t> 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=last%2:42:00:: | definition=persist for a specified period of time | synonyms=endure | examples=The bad weather lasted for three days
2. sense_key=last%2:42:01:: | definition=continue to live through hardship or adversity | synonyms=survive, live, live on, go, endure, hold up | examples=We went without water and food for 3 days; These superstitions survive in the backwaters of America

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `last`
    *   Target surface form: `lasting`
    *   Context: "...given once every three weeks as an intravenous infusion <t>lasting</t> 10 minutes."
    *   Candidate senses:
        1.  `last%2:42:00::`: persist for a specified period of time (synonym: endure; example: "The bad weather lasted for three days")
        2.  `last%2:42:01::`: continue to live through hardship or adversity (synonyms: survive, live; example: "We went without water and food for 3 days")

    *   The sentence describes the duration of an intravenous infusion: "an intravenous infusion lasting 10 minutes."
    *   This refers to the amount of time the process takes (duration).

    *   Sense 1: "persist for a specified period of time". This fits perfectly. The infusion persists/continues for 10 minutes.
    *   Sense 2: "continue to live through hardship or adversity". This does not fit. An infusion is not a living being experiencing hardship.

    *   Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: minute
Target surface form: minutes
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 <t>minutes</t>. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=minute%1:28:00:: | definition=a unit of time equal to 60 seconds or 1/60th of an hour | synonyms=min | examples=he ran a 4 minute mile
2. sense_key=minute%1:28:01:: | definition=an indefinitely short time | synonyms=moment, mo, second, bit | examples=wait just a moment; in a mo
3. sense_key=minute%1:28:02:: | definition=a particular point in time | synonyms=moment, second, instant | examples=the moment he arrived the party began
4. sense_key=minute%1:23:00:: | definition=a unit of angular distance equal to a 60th of a degree | synonyms=arcminute, minute of arc
5. sense_key=minute%1:10:00:: | definition=a short note | examples=the secretary keeps the minutes of the meeting
6. sense_key=minute%1:07:00:: | definition=distance measured by the time taken to cover it | synonyms=hour | examples=we live an hour from the airport; its just 10 minutes away

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `minute`
    *   Target surface form: `minutes`
    *   Context: "...an intravenous infusion lasting 10 <t>minutes</t>."
    *   Candidate senses:
        1.  `minute%1:28:00::`: unit of time equal to 60 seconds or 1/60th of an hour.
        2.  `minute%1:28:01::`: an indefinitely short time.
        3.  `minute%1:28:02::`: a particular point in time.
        4.  `minute%1:23:00::`: unit of angular distance.
        5.  `minute%1:10:00::`: a short note (minutes of a meeting).
        6.  `minute%1:07:00::`: distance measured by time.

    *   The phrase is "lasting 10 minutes".
    *   This refers to a duration of time.
    *   "10 minutes" clearly refers to the unit of time (60 seconds each).

    *   Sense 1: "a unit of time equal to 60 seconds or 1/60th of an hour". This fits perfectly.
    *   Sense 2: "an indefinitely short time". Not applicable (it's a specific number, 10).
    *   Sense 3: "a particular point in time". Not applicable (it's a duration).
    *   Sense 4: "unit of angular distance". Not applicable.
    *   Sense 5: "a short note". Not applicable.
    *   Sense 6: "distance measured by the time taken". Not applicable.

    *   The best sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduce
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question
3. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
4. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
5. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
6. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
7. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
8. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
9. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
10. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
11. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
12. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
13. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
14. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
15. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
16. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
17. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
18. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
19. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
20. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `reduce`
    *   Target surface form: `reduce`
    *   Context: "To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid..."
    *   Meaning: In this context, "reduce side effects" means to make the side effects less severe, less frequent, or smaller in number/intensity.

    *   1: cut down on; make a reduction in (e.g., reduce fat intake) - *Possible, but usually refers to quantity of something consumed or a budget.*
    *   2: make less complex (e.g., reduce a problem) - *Incorrect.*
    *   3: bring to humbler or weaker state or condition (e.g., reduced to slavery) - *Incorrect.*
    *   4: simplify mathematical equation - *Incorrect.*
    *   5: lower in grade or rank - *Incorrect.*
    *   6: be the essential element (boil down) - *Incorrect.*
    *   7: reduce in size; reduce physically (shrink) - *Incorrect.*
    *   8: lessen and make more modest (e.g., reduce standard of living) - *Incorrect.*
    *   9: make smaller (scale down an image) - *Incorrect.*
    *   10: remove oxygen (chemistry) - *Incorrect.*
    *   11: narrow or limit (e.g., reduce influx) - *Incorrect.*
    *   12: put down by force (repress) - *Incorrect.*
    *   13: undergo meiosis - *Incorrect.*
    *   14: reposition a broken bone - *Incorrect.*
    *   15: destress a sound - *Incorrect.*
    *   16: reduce in scope while retaining essential elements (abridge) - *Incorrect.*
    *   17: be cooked until little liquid is left - *Incorrect.*
    *   18: cook until little liquid is left - *Incorrect.*
    *   19: lessen strength or flavor of a solution (dilute) - *Incorrect.*
    *   20: take off weight - *Incorrect.*

    *   Wait, looking back at the senses provided, none of them explicitly say "lessen the severity or intensity of symptoms/effects." Let's re-examine Sense 1.
    *   Sense 1: "cut down on; make a reduction in" (Synonyms: cut down, cut back, trim). Example: "reduce your daily fat intake".
    *   Is there a better one?
    *   Sense 11: "narrow or limit" (Synonyms: tighten). Example: "reduce the influx of foreigners".
    *   Sense 8: "lessen and make more modest". Example: "reduce one's standard of living".
    *   Sense 9: "make smaller". Example: "reduce an image".

    Let's look at the options again. "Reduce side effects" means to make them less severe or to decrease their occurrence.
    Sense 1: "cut down on; make a reduction in". This is the most general sense of "making something less".

    Let's double-check if I missed any.
    Sense 1: cut down on; make a reduction in.
    Sense 8: lessen and make more modest.
    Sense 11: narrow or limit.

    In medical contexts, "reducing side effects" usually means decreasing their frequency or severity. "Cut down on" or "make a reduction in" (Sense 1) fits this general meaning of decreasing the amount or intensity of something.

    Let's compare Sense 1 and Sense 11.
    Sense 1: "cut down on; make a reduction in"
    Sense 11: "narrow or limit"

    "Reduce side effects" is more about decreasing the amount/severity than "narrowing" or "limiting" them in the sense of a boundary.

    Let's look at Sense 1 again. "reduce your daily fat intake". This is reducing the quantity. Side effects can be quantified (number of occurrences) or their intensity can be reduced.

    Is there any other sense?
    Sense 8: "lessen and make more modest". This doesn't fit "side effects".

    Actually, looking at WordNet (the source of these senses), "reduce" often has a general sense of "make smaller or less in amount, degree, or size". Sense 1 ("cut down on; make a reduction in") is the closest match among the provided options for decreasing the occurrence or severity of side effects.

    Wait, let me re-read the senses one more time.
    1. cut down on; make a reduction in
    2. make less complex
    3. bring to humbler or weaker state
    4. simplify mathematical equation
    5. lower in grade or rank
    6. be the essential element
    7. reduce in size; reduce physically
    8. lessen and make more modest
    9. make smaller
    10. remove oxygen
    11. narrow or limit
    12. put down by force
    13. undergo meiosis
    14. reposition a broken bone
    15. destress a sound
    16. reduce in scope
    17. be cooked until little liquid is left
    18. cook until little liquid is left
    19. lessen strength or flavor of a solution
    20. take off weight

    Sense 1 is the most plausible. "Make a reduction in [the side effects]".

    Let's check if "reduce" in "reduce side effects" could be Sense 11 ("narrow or limit"). "Limit side effects" is a common phrase, but "reduce" usually means to make them less severe.

    Let's check Sense 1 again. "cut down on; make a reduction in". This is the most general "decrease" sense.

    Comparing Sense 1 and Sense 9:
    Sense 1: cut down on; make a reduction in.
    Sense 9: make smaller (scale down an image).
    Sense 1 is better for abstract things like "side effects" or "fat intake".

    Comparing Sense 1 and Sense 8:
    Sense 8: lessen and make more modest (standard of living).
    Sense 1 is better.

    Final check: "To reduce side effects" -> "To make a reduction in side effects" (Sense 1).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: side_effect
Target surface form: side effects
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce <t>side effects</t>, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
2. sense_key=side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `side_effect`
    *   Target surface form: `side effects`
    *   Context: A medical text describing the use of Alimta (anticancer chemotherapy), mentioning dosage, administration, and the use of corticosteroids, folic acid, and vitamin B12 to reduce "side effects".
    *   Candidate senses:
        1.  `side_effect%1:26:00::`: a secondary and usually adverse effect of a drug or therapy.
        2.  `side_effect%1:19:00::`: any adverse and unwanted secondary effect (synonym: fallout).

    *   The context is explicitly about a medicine (Alimta), chemotherapy, and medical treatment.
    *   The phrase "To reduce side effects, patients should take a corticosteroid..." clearly refers to the adverse effects caused by the drug/therapy.

    *   Sense 1 specifically mentions "a drug or therapy".
    *   Sense 2 is a more general "any adverse and unwanted secondary effect" (like political or social fallout).

    *   Sense 1 is the precise fit for a medical context involving drugs.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, <t>patients</t> should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text describing the administration of the drug Alimta. Specifically: "To reduce side effects, <t>patients</t> should take a corticosteroid and folic acid..."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The context is clearly medical.
    *   The sentence "To reduce side effects, patients should take a corticosteroid..." refers to people receiving medical treatment (Alimta).
    *   Sense 1 describes a person requiring medical care.
    *   Sense 2 describes a linguistic/semantic role (the "patient" in a sentence).

    *   Sense 1 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `type`
    *   Target surface form: `type`
    *   Context: "...patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin), and receive injections of vitamin B12 during treatment with Alimta."
    *   Candidate senses:
        1.  `type%1:09:00::`: a subdivision of a particular kind of thing (e.g., "what type of sculpture do you prefer?")
        2.  `type%1:18:00::`: a person of a specified kind (usually with many eccentricities)
        3.  `type%1:14:01::`: (biology) the taxonomic group whose characteristics are used to define the next higher taxon
        4.  `type%1:10:01::`: printed characters
        5.  `type%1:10:00::`: all of the tokens of the same symbol
        6.  `type%1:06:00::`: a small metal block bearing a raised character on one end

    *   The phrase is "a type of vitamin".
    *   Folic acid is a specific kind or category within the broader group of vitamins.
    *   This matches the definition "a subdivision of a particular kind of thing".

    *   Sense 1: "a subdivision of a particular kind of thing" - Fits perfectly.
    *   Sense 2: "a person of a specified kind" - Does not fit (folic acid is not a person).
    *   Sense 3: "(biology) the taxonomic group..." - This is a very specific biological/taxonomic meaning, not the general "kind of" meaning used here.
    *   Sense 4: "printed characters" - Does not fit.
    *   Sense 5: "all of the tokens of the same symbol" - Does not fit.
    *   Sense 6: "a small metal block..." - Does not fit.

    *   The best fit is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: injection
Target surface form: injections
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=injection%1:04:00:: | definition=the forceful insertion of a substance under pressure
2. sense_key=injection%1:27:00:: | definition=any solution that is injected (as into the skin) | synonyms=injectant
3. sense_key=injection%1:04:01:: | definition=the act of putting a liquid into the body by means of a syringe | synonyms=shot | examples=the nurse gave him a flu shot

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `injection`
    *   Target surface form: `injections`
    *   Context: "...patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta."
    *   Candidate senses:
        1.  `injection%1:04:00::`: the forceful insertion of a substance under pressure (General physical process).
        2.  `injection%1:27:00::`: any solution that is injected (as into the skin) (The substance itself).
        3.  `injection%1:04:01::`: the act of putting a liquid into the body by means of a syringe (The medical procedure/shot).

    *   The sentence says patients "receive injections of vitamin B12".
    *   "Receive injections" typically refers to the medical act/procedure of being given a shot.
    *   Sense 1 is too general (forceful insertion under pressure).
    *   Sense 2 refers to the solution (the injectant). While one could "receive a solution", the phrase "receive injections" almost always refers to the act/event of the shot.
    *   Sense 3 specifically mentions "the act of putting a liquid into the body by means of a syringe" and provides the synonym "shot". "Receive shots of vitamin B12" is a perfect paraphrase.

    *   Sense 3 is the most precise fit for the medical context of receiving a treatment via syringe.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during <t>treatment</t> with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "treatment"
    *   Context: A medical text describing the use of Alimta (an anticancer chemotherapy drug), dosage, administration, and side effect management. The specific phrase is "receive injections of vitamin B12 during <t>treatment</t> with Alimta."
    *   Candidate senses:
        1.  `treatment%1:04:00`: care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury).
        2.  `treatment%1:04:01`: the management of someone or something (handling).
        3.  `treatment%1:07:00`: a manner of dealing with something artistically.
        4.  `treatment%1:10:00`: an extended communication dealing with some particular topic (discussion).

    *   The context is clearly medical: "medicine", "prescription", "anticancer chemotherapy", "dose", "intravenous infusion", "side effects", "corticosteroid", "folic acid", "vitamin B12".
    *   The phrase "during treatment with Alimta" refers to the period during which the patient is receiving the medical care/drug to treat their condition.

    *   Sense 1: "care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury)". This fits perfectly.
    *   Sense 2: "the management of someone or something". Too general; doesn't capture the medical aspect as well as Sense 1.
    *   Sense 3: "manner of dealing with something artistically". Irrelevant.
    *   Sense 4: "an extended communication". Irrelevant.

    *   The best fit is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is <t>given</t> with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 19}
```

content:
```json
{"sense_index": 19}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "When Alimta is <t>given</t> with cisplatin, an anti-emetic medicine... should also be given..."
    *   Meaning: In this medical context, "given" refers to the administration of a drug (Alimta) to a patient.

    *   Sense 1: cause to have (black eye, cold) - No.
    *   Sense 2: be the cause or source of (trouble, information) - No.
    *   Sense 3: transfer possession (money, lessons) - No.
    *   Sense 4: convey or reveal information (name) - No.
    *   Sense 5: convey compliment, regards, etc. - No.
    *   Sense 6: organize/responsible for (party) - No.
    *   Sense 7: convey/communicate (smile, look) - No.
    *   Sense 8: give as a present - No.
    *   Sense 9: cause to happen (victory) - No.
    *   Sense 10: dedicate (thought, priority) - No.
    *   Sense 11: give or supply (milk, crop) - No.
    *   Sense 12: transmit knowledge/skills - No.
    *   Sense 13: bring about (establish depth) - No.
    *   Sense 14: leave with temporarily - No.
    *   Sense 15: emit or utter (gulp, yelp) - No.
    *   Sense 16: endure loss of (life) - No.
    *   Sense 17: place into hands/custody (hand me the spoon) - No.
    *   Sense 18: give entirely to a person/cause - No.
    *   Sense 19: give (as medicine) - Example: "I gave him the drug". This matches perfectly.
    *   Sense 20: give or convey physically (First Aid, punch) - Close, but Sense 19 is specific to medicine.
    *   Sense 21: bestow (homage, thanks) - No.
    *   Sense 22: bestow officially (degree, divorce) - No.
    *   Sense 23: move to make room - No.
    *   Sense 24: give food to (feed) - No.
    *   Sense 25: contribute to some cause - No.
    *   Sense 26: break down (collapse) - No.
    *   Sense 27: estimate duration/outcome - No.
    *   Sense 28: execute and deliver (bond) - No.
    *   Sense 29: deliver in exchange - No.
    *   Sense 30: afford access to (door opens to) - No.
    *   Sense 31: present to view (sign) - No.
    *   Sense 32: perform for an audience (concert) - No.
    *   Sense 33: be flexible under stress - No.
    *   Sense 34: propose (toast) - No.
    *   Sense 35: accord by verdict - No.
    *   Sense 36: manifest or show (promise, evidence) - No.
    *   Sense 37: offer in good faith (word) - No.
    *   Sense 38: submit for consideration (opinion, excuse) - No.
    *   Sense 39: guide or direct - No.
    *   Sense 40: allow to have or take - No.
    *   Sense 41: inflict as punishment - No.
    *   Sense 42: occur (what gives?) - No.
    *   Sense 43: consent to sexual intercourse - No.
    *   Sense 44: proffer (body part) - No.

    *   Sense 19: "give (as medicine)" with example "I gave him the drug".
    *   The context is "When Alimta is given with cisplatin...", where Alimta and cisplatin are chemotherapy drugs. This is a direct match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic <t>medicine</t> (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicine`
    *   Context: "...an anti-emetic <t>medicine</t> (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `medicine%1:09:00::`: branches of medical science (medical specialty).
        2.  `medicine%1:06:00::`: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).
        3.  `medicine%1:04:00::`: the learned profession (practice of medicine).
        4.  `medicine%1:04:02::`: punishment for one's actions (take your medicine).

    *   The context refers to an "anti-emetic medicine" used to "prevent vomiting" given alongside "cisplatin" (a chemotherapy drug).
    *   This clearly refers to a drug or medication.

    *   Sense 1: Medical science/specialty (Incorrect).
    *   Sense 2: Medication/medicinal drug (Correct).
    *   Sense 3: Medical profession (Incorrect).
    *   Sense 4: Punishment (Incorrect).

    *   The best sense is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to <t>prevent</t> vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `prevent`
    *   Target surface form: `prevent`
    *   Context: "...an anti-emetic medicine (to <t>prevent</t> vomiting) and fluids (to prevent dehydration)..."
    *   Candidate senses:
        1.  `prevent%2:41:01::`: keep from happening or arising; make impossible (synonyms: forestall, foreclose, preclude, forbid).
        2.  `prevent%2:41:00::`: stop (someone or something) from doing something or being in a certain state (synonyms: keep).

    *   "prevent vomiting"
    *   "prevent dehydration"
    *   In both cases, the goal is to stop a condition (vomiting, dehydration) from occurring or starting.

    *   Sense 1: "keep from happening or arising; make impossible". This fits "prevent vomiting" and "prevent dehydration" well.
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state". This often implies an agent or a process already in motion (e.g., "prevent the cancer from spreading").

    *   Sense 1 focuses on the *occurrence* of the event (preventing the event from happening).
    *   Sense 2 focuses on *stopping* an entity from acting or being in a state.
    *   "Vomiting" and "dehydration" are events/conditions that the medicine/fluids are intended to keep from happening in the first place.

    *   Sense 1: "keep from happening or arising" -> "keep vomiting from happening".
    *   Sense 2: "stop (someone or something) from doing something" -> "stop the patient from vomiting".

    Wait, let's look at the examples:
    *   Sense 1: "Your role in the projects precludes your involvement..." (makes it impossible).
    *   Sense 2: "We must prevent the cancer from spreading" (stop it from doing something).

    Comparing "prevent vomiting" to "prevent the cancer from spreading":
    "Vomiting" is the action/event. "Prevent vomiting" means to keep the act of vomiting from happening.
    "Prevent dehydration" means to keep the state of dehydration from arising.

    Looking at the definitions again:
    Sense 1: "keep from happening or arising"
    Sense 2: "stop (someone or something) from doing something or being in a certain state"

    "Vomiting" can be seen as the "something" (the event) happening.
    "Dehydration" can be seen as the "certain state".

    However, "prevent vomiting" is a classic example of keeping an event from happening (Sense 1). "Prevent dehydration" is keeping a state from arising (Sense 1).

    Let's re-evaluate Sense 2: "stop (someone or something) from doing something". This usually takes an object (the person/thing being stopped). "Prevent the patient from vomiting". In the text, it's "prevent vomiting" (direct object is the action).

    If the object is the action/event itself ("vomiting"), Sense 1 ("keep from happening") is more precise.

    Sense 1: keep from happening or arising.
    Sense 2: stop (someone or something) from doing something.

    "Prevent vomiting" -> keep vomiting from happening. (Sense 1)
    "Prevent dehydration" -> keep dehydration from arising. (Sense 1)

    If it were "prevent the patient from vomiting", it would be Sense 2.

    Therefore, Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: fluid
Target surface form: fluids
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and <t>fluids</t> (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=fluid%1:27:02:: | definition=a substance that is fluid at room temperature and pressure
2. sense_key=fluid%1:27:00:: | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `fluid`
    *   Target surface form: `fluids`
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and <t>fluids</t> (to prevent dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `fluid%1:27:02::`: a substance that is fluid at room temperature and pressure.
        2.  `fluid%1:27:00::`: continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas.

    *   The context describes a medical treatment (chemotherapy with Alimta and cisplatin).
    *   The specific phrase is "fluids (to prevent dehydration)".
    *   In a medical context, "giving fluids" refers to administering liquids (usually saline or other intravenous solutions) to keep the patient hydrated.

    *   Sense 1: "a substance that is fluid at room temperature and pressure". This is a more specific definition often used in chemistry or physics to describe the state of a substance.
    *   Sense 2: "continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas". This is a broader definition of what a fluid is.

    *Wait*, let me re-examine the WordNet senses provided.
    Sense 1: `fluid%1:27:02::` - a substance that is fluid at room temperature and pressure.
    Sense 2: `fluid%1:27:00::` - continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas.

    Actually, looking at how "fluids" is used in medicine (IV fluids), it refers to liquids.
    Sense 2 defines fluid as "a liquid or a gas".
    Sense 1 defines it as "a substance that is fluid at room temperature and pressure".

    In medical terminology, "fluids" almost always refers to liquids (water, saline, etc.).
    Sense 2 is the general definition of a fluid (liquid or gas).
    Sense 1 is a slightly different way of saying it's a substance that behaves as a fluid under standard conditions.

    Let's look at the WordNet hierarchy if possible (mentally).
    `fluid%1:27:00` is the top-level definition of a fluid (liquid or gas).
    `fluid%1:27:02` is a substance that is fluid at room temperature and pressure.

    In the context of "giving fluids to prevent dehydration", we are talking about the *substances* (the liquids) being administered.

    Let's compare:
    - "Give the patient fluids" -> Give the patient liquids.
    - Is a liquid "continuous amorphous matter that tends to flow" (Sense 2) or "a substance that is fluid at room temperature and pressure" (Sense 1)?

    Usually, when "fluids" is used as a count noun (plural "fluids"), it refers to specific types of liquid substances (e.g., bodily fluids, IV fluids).
    Sense 1 ("a substance that is fluid...") fits the count noun usage better ("fluids" = substances that are fluid).
    Sense 2 ("continuous amorphous matter...") is more of a mass noun definition describing the nature of the state of matter.

    Let's double-check:
    Sense 1: "a substance that is fluid at room temperature and pressure"
    Sense 2: "continuous amorphous matter that tends to flow..."

    If I say "The patient needs fluids", I mean they need liquid substances.
    Sense 1 describes the substance. Sense 2 describes the matter/state.

    In medical contexts, "IV fluids" are substances.

    Let's re-read:
    Sense 1: `fluid%1:27:02::` | definition=a substance that is fluid at room temperature and pressure
    Sense 2: `fluid%1:27:00::` | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

    If the context is "fluids (to prevent dehydration)", it refers to the liquid substances administered. Sense 1 is the most appropriate for "substances".

    Wait, let me think again. Is "fluid" in "IV fluids" referring to the general category of liquids/gases or specifically to substances that are liquid?
    Dehydration is prevented by liquids. Liquids are substances that are fluid at room temperature.

    Let's look at the WordNet structure for `fluid`:
    - fluid (n)
        - fluid%1:27:00 (liquid or gas)
        - fluid%1:27:02 (substance that is fluid at room temperature and pressure)

    Actually, in many WordNet-based datasets, the "substance" definition (Sense 1 here) is used for specific liquids (like "bodily fluids" or "hydraulic fluid"), while the "matter" definition (Sense 2) is the general physical definition.

    "Fluids (to prevent dehydration)" refers to the liquid substances being infused.

    Let's check if there's any other nuance.
    Sense 1: a substance that is fluid at room temperature and pressure.
    Sense 2: continuous amorphous matter that tends to flow...

    If you are giving "fluids", you are giving "substances". You aren't giving "continuous amorphous matter".

    Therefore, Sense 1 is the better fit for the count noun "fluids" in a medical context.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to <t>prevent</t> dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `prevent`
    *   Target surface form: `prevent`
    *   Context: "...and fluids (to <t>prevent</t> dehydration) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `prevent%2:41:01::`: keep from happening or arising; make impossible (forestall, foreclose, preclude, forbid).
        2.  `prevent%2:41:00::`: stop (someone or something) from doing something or being in a certain state (keep).

    *   The phrase is "to prevent dehydration".
    *   Dehydration is a state or a condition.
    *   The goal is to stop the patient from entering the state of dehydration.

    *   Sense 1: "keep from happening or arising; make impossible". This often refers to events or occurrences (e.g., "prevent an accident").
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state". This specifically mentions "being in a certain state".

    *   Dehydration is a state.
    *   "Prevent dehydration" means stopping the person from being in the state of dehydration.
    *   Comparing the examples:
        *   Sense 1: "Your role... precludes your involvement" (making an action impossible).
        *   Sense 2: "prevent the cancer from spreading" (stopping a process/state change).
    *   Actually, looking closer at Sense 1 ("keep from happening or arising") vs Sense 2 ("stop... from... being in a certain state").
    *   Dehydration is both an event (happening) and a state (being dehydrated).
    *   However, Sense 2 explicitly mentions "being in a certain state".
    *   Let's re-evaluate.
    *   Sense 1: "keep from happening or arising".
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state".
    *   In "prevent dehydration", the object is "dehydration" (the state itself).
    *   If the sentence were "prevent the patient from becoming dehydrated", it would clearly be Sense 2.
    *   If the sentence is "prevent dehydration", it's treating dehydration as the thing to be kept from happening.
    *   Wait, let's look at the synonyms.
        *   Sense 1: forestall, foreclose, preclude.
        *   Sense 2: keep.
    *   "Keep dehydration" doesn't make sense. "Preclude dehydration" makes some sense.
    *   Let's look at the examples again.
        *   Sense 1: "My sense of tact forbids an honest answer" (prevents the answer from happening).
        *   Sense 2: "prevent the cancer from spreading" (stops the cancer from doing something).
    *   Actually, "prevent dehydration" is very similar to "prevent the cancer from spreading" in terms of stopping a negative medical condition from occurring/progressing.
    *   Wait, "prevent dehydration" -> stop the state of dehydration from arising.
    *   Sense 1: "keep from happening or arising".
    *   Sense 2: "stop (someone or something) from doing something or being in a certain state".
    *   In "prevent dehydration", the object is the state itself. In Sense 2, the object is the *person/thing* who is stopped from being in the state.
    *   Example Sense 2: "prevent the cancer from spreading" (Object: cancer).
    *   Example Sense 2: "kept me from falling asleep" (Object: me).
    *   In "prevent dehydration", the object is "dehydration".
    *   Therefore, it fits Sense 1 ("keep [dehydration] from happening or arising") better than Sense 2 ("stop [dehydration] from... being in a certain state").

    *   Sense 1: prevent [event/condition] from happening.
    *   Sense 2: prevent [person/thing] from [action/state].
    *   Context: "prevent dehydration".
    *   Object = dehydration (the condition).
    *   This matches Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dehydration
Target surface form: dehydration
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent <t>dehydration</t>) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dehydration%1:26:00:: | definition=dryness resulting from the removal of water | synonyms=desiccation
2. sense_key=dehydration%1:26:01:: | definition=depletion of bodily fluids
3. sense_key=dehydration%1:22:00:: | definition=the process of extracting moisture | synonyms=desiccation, drying up, evaporation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "dehydration"
    *   Context: "...and fluids (to prevent <t>dehydration</t>) should also be given before or after the cisplatin dose."
    *   Candidate senses:
        1.  `dehydration%1:26:00::`: dryness resulting from the removal of water (synonym: desiccation).
        2.  `dehydration%1:26:01::`: depletion of bodily fluids.
        3.  `dehydration%1:22:00::`: the process of extracting moisture (synonyms: desiccation, drying up, evaporation).

    *   The context is medical (Alimta, chemotherapy, cisplatin, intravenous infusion, fluids).
    *   The phrase "fluids (to prevent dehydration)" refers to giving a patient fluids to prevent the loss or depletion of water/fluids from their body.

    *   Sense 1: "dryness resulting from the removal of water" (more general or chemical/physical).
    *   Sense 2: "depletion of bodily fluids" (specifically medical/biological).
    *   Sense 3: "the process of extracting moisture" (a process, like industrial drying).

    *   Sense 2 is the precise medical definition for the loss of water from the body, which is what "fluids" are given to prevent in a clinical setting.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 19}
```

reasoning_content:
*   Target lemma: `give`
    *   Target surface form: `given`
    *   Context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose."
    *   The context is about medical treatment, specifically administering medications (Alimta, cisplatin, anti-emetic medicine, and fluids).

    *   Sense 1: cause to have (abstract/physical) - e.g., "gave him a black eye"
    *   Sense 2: be the cause or source of - e.g., "gave me a lot of trouble"
    *   Sense 3: transfer possession - e.g., "gave her my money"
    *   Sense 4: convey or reveal information - e.g., "Give one's name"
    *   Sense 5: convey compliment, regards, etc. - e.g., "give the orders"
    *   Sense 6: organize/responsible for - e.g., "hold a reception"
    *   Sense 7: convey/communicate (smile, look) - e.g., "gave me a dirty look"
    *   Sense 8: give as a present - e.g., "give her for her birthday"
    *   Sense 9: cause to happen - e.g., "gave the team the victory"
    *   Sense 10: dedicate - e.g., "give thought to"
    *   Sense 11: give or supply - e.g., "cow brings in 5 liters of milk"
    *   Sense 12: transmit knowledge/skills - e.g., "give a secret"
    *   Sense 13: bring about - e.g., "establishes depth"
    *   Sense 14: leave with temporarily - e.g., "give you my keys"
    *   Sense 15: emit or utter - e.g., "give a yelp"
    *   Sense 16: endure loss of - e.g., "gave his life"
    *   Sense 17: place into hands/custody - e.g., "hand me the spoon"
    *   Sense 18: give entirely to a person/cause - e.g., "give one's talents"
    *   Sense 19: give (as medicine) - e.g., "I gave him the drug"
    *   Sense 20: give or convey physically (apply) - e.g., "gave him First Aid"
    *   Sense 21: bestow (render thanks) - e.g., "give homage"
    *   Sense 22: bestow officially (grant) - e.g., "grant a degree"
    *   Sense 23: move to make room - e.g., "give way"
    *   Sense 24: give food to (feed) - e.g., "feed the starving children"
    *   Sense 25: contribute to some cause - e.g., "gave at the office"
    *   Sense 26: break down - e.g., "wall collapsed"
    *   Sense 27: estimate duration/outcome - e.g., "gave the patient three months to live"
    *   Sense 28: execute and deliver - e.g., "Give bond"
    *   Sense 29: deliver in exchange - e.g., "give you three books for four CDs"
    *   Sense 30: afford access to - e.g., "doors give onto a terrace"
    *   Sense 31: present to view - e.g., "gave the sign to start"
    *   Sense 32: perform for an audience - e.g., "giving another concert"
    *   Sense 33: be flexible under stress - e.g., "material doesn't give"
    *   Sense 34: propose - e.g., "gave the first of many toasts"
    *   Sense 35: accord by verdict - e.g., "give a decision"
    *   Sense 36: manifest or show - e.g., "gives promise"
    *   Sense 37: offer in good faith - e.g., "gave her his word"
    *   Sense 38: submit for consideration - e.g., "give one's opinion"
    *   Sense 39: guide or direct - e.g., "gave me to think"
    *   Sense 40: allow to have or take - e.g., "give you two minutes"
    *   Sense 41: inflict as punishment - e.g., "gave the boy a good spanking"
    *   Sense 42: occur - e.g., "what gives?"
    *   Sense 43: consent to sexual intercourse - e.g., "gave herself to many men"
    *   Sense 44: proffer (a body part) - e.g., "gave her hand"

    *   The target word "given" is used in the context of administering medicine ("anti-emetic medicine... and fluids... should also be given").
    *   Sense 19 specifically says "give (as medicine)" and provides the example "I gave him the drug".

    *   Sense 19 is a perfect match for the context of administering medication.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: before
Target surface form: before
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=before%4:02:03:: | definition=earlier in time; previously | synonyms=earlier | examples=I had known her before; as I said before
2. sense_key=before%4:02:01:: | definition=at or in the front | synonyms=ahead, in front | examples=I see the lights of a town ahead; the road ahead is foggy

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "before"
    *   Target surface form: "before"
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose."
    *   Candidate senses:
        1.  `before%4:02:03::` (earlier in time; previously)
        2.  `before%4:02:01::` (at or in the front)

    *   The sentence discusses the timing of administering medication ("given before or after the cisplatin dose").
    *   "Before" here refers to a temporal sequence (time), not a physical position (front).

    *   Sense 1: "earlier in time; previously" - This fits perfectly.
    *   Sense 2: "at or in the front" - This refers to spatial position, which is incorrect here.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: after
Target surface form: after
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=after%4:02:01:: | definition=happening at a time subsequent to a reference time | synonyms=subsequently, later, afterwards, afterward, later on | examples=he apologized subsequently; he's going to the store but he'll be back here later
2. sense_key=after%4:02:00:: | definition=behind or in the rear | examples=and Jill came tumbling after

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "after"
    *   Target surface form: "after"
    *   Context: "...an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose."
    *   Candidate senses:
        1.  `after%4:02:01::`: happening at a time subsequent to a reference time (subsequently, later).
        2.  `after%4:02:00::`: behind or in the rear.

    *   The sentence discusses the timing of administering medicine: "given before or after the cisplatin dose."
    *   "Before" and "after" here refer to temporal sequence (time).
    *   Sense 1 refers to time ("happening at a time subsequent to a reference time").
    *   Sense 2 refers to spatial position ("behind or in the rear").

    *   The context is clearly temporal (timing of medication), not spatial.
    *   Therefore, Sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `dose`
    *   Target surface form: `dose`
    *   Context: A medical text describing the administration of Alimta and cisplatin (chemotherapy). Specifically: "...before or after the cisplatin <t>dose</t>."
    *   Candidate senses:
        1.  `dose%1:06:00::`: a measured portion of medicine taken at any one time (synonym: dosage).
        2.  `dose%1:23:00::`: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time (synonym: dosage).
        3.  `dose%1:26:00::`: a communicable infection transmitted by sexual intercourse...
        4.  `dose%1:06:01::`: street name for LSD.

    *   The context is clearly medical/pharmacological.
    *   "cisplatin dose" refers to the specific amount of the drug cisplatin administered to the patient.
    *   Sense 3 (STD) and Sense 4 (LSD) are completely irrelevant.
    *   Comparing Sense 1 and Sense 2:
        *   Sense 1: "a measured portion of medicine taken at any one time"
        *   Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"
    *   In medical contexts, "dose" often refers to the specific amount given (the portion).
    *   Looking at the context again: "The recommended dose of Alimta is 500 mg per square metre... before or after the cisplatin dose."
    *   Sense 1 is the most common definition for a specific administration of a medicine. Sense 2 is slightly more technical/general (active agent/radiation).
    *   Usually, in WordNet, `dose%1:06:00` is the standard "measured portion of medicine".

    *   Sense 1: `dose%1:06:00` - a measured portion of medicine taken at any one time.
    *   Sense 2: `dose%1:23:00` - the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
    *   Wait, let me re-evaluate. Is there a subtle difference?
    *   "Measured portion" (Sense 1) vs "Quantity of an active agent" (Sense 2).
    *   In the context of chemotherapy (cisplatin), it's a measured portion of the medicine.
    *   Let's check common usage in WSD datasets or WordNet hierarchies.
    *   Actually, looking at the provided senses:
        1. `dose%1:06:00`
        2. `dose%1:23:00`
    *   In many WordNet versions, `dose%1:06:00` is the primary sense for a medical dose.

    *   Context: "...before or after the cisplatin dose."
    *   This refers to the specific instance/amount of the drug administered.
    *   Sense 1 fits perfectly.

    *   Sense 1: a measured portion of medicine taken at any one time.
    *   Sense 2: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
    *   While very similar, Sense 1 is the more direct fit for "a dose of [medicine]". Sense 2 is often used in toxicology or radiation therapy (e.g., "a dose of radiation"). Since cisplatin is a medicine, Sense 1 is the most natural fit.

    *   Sense 1: `dose%1:06:00`
    *   Sense 2: `dose%1:23:00`
    *   Sense 3: `dose%1:26:00`
    *   Sense 4: `dose%1:06:01`
    *   The index for `dose%1:06:00` is 1.