[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: alone
Target surface form: alone
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=alone%5:00:00:unsocial:00 | definition=isolated from others | examples=could be alone in a crowded room; was alone with her thoughts
2. sense_key=alone%5:00:00:unaccompanied:00 | definition=lacking companions or companionship | synonyms=lone, lonely, solitary | examples=he was alone when we met him; she is alone much of the time
3. sense_key=alone%5:00:00:exclusive:00 | definition=exclusive of anyone or anything else | synonyms=only | examples=she alone believed him; cannot live by bread alone
4. sense_key=alone%5:00:00:incomparable:00 | definition=radically distinctive and without equal | synonyms=unique, unequaled, unequalled, unparalleled | examples=he is alone in the field of microbiology; this theory is altogether alone in its penetration of the problem

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: "alone"
    *   Target surface form: "alone"
    *   Context: "...when the cancer is unresectable (cannot be removed by surgery <t>alone</t>) and malignant..."
    *   Candidate senses:
        1.  `unsocial`: isolated from others.
        2.  `unaccompanied`: lacking companions or companionship.
        3.  `exclusive`: exclusive of anyone or anything else (synonym: only).
        4.  `incomparable`: radically distinctive and without equal.

    *   The phrase is "cannot be removed by surgery alone".
    *   This means surgery *by itself* (without other treatments like chemotherapy or radiation) is not sufficient to remove the cancer.
    *   "Surgery alone" = "only surgery".

    *   Sense 1 (unsocial): Not applicable.
    *   Sense 2 (unaccompanied): Not applicable (surgery is not a person lacking companions).
    *   Sense 3 (exclusive): "exclusive of anyone or anything else", synonym "only". This fits perfectly: "cannot be removed by surgery only".
    *   Sense 4 (incomparable): Not applicable.

    *   Sense 3 is the correct fit.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spread
Target surface form: spread
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=spread%2:35:00:: | definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. sense_key=spread%2:35:07:: | definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
3. sense_key=spread%2:42:00:: | definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
4. sense_key=spread%2:35:03:: | definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
5. sense_key=spread%2:32:00:: | definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. sense_key=spread%2:32:02:: | definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. sense_key=spread%2:38:00:: | definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. sense_key=spread%2:38:02:: | definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. sense_key=spread%2:35:12:: | definition=cover by spreading something over | examples=spread the bread with cheese
10. sense_key=spread%2:35:13:: | definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

finish_reason: stop

content:
```json
{"sense_index": 2}
```

role: assistant

reasoning_content:
*   Target lemma: `spread`
    *   Target surface form: `spread`
    *   Context: "...malignant (has <t>spread</t>, or is likely to spread easily, to other parts of the body)..."
    *   Meaning: In the context of cancer (malignancy), "spread" refers to the movement of cancer cells from the primary site to other parts of the body (metastasis).

    *   Sense 1: distribute or disperse widely (active, e.g., invaders spread language).
    *   Sense 2: become distributed or widespread (intransitive, e.g., infection spread, optimism spread).
    *   Sense 3: spread across or over (e.g., oil spot spread across water).
    *   Sense 4: spread out or open from a closed state (e.g., open the map).
    *   Sense 5: cause to become widely known (e.g., spread information).
    *   Sense 6: become widely known and passed on (e.g., rumor spread).
    *   Sense 7: strew or distribute over an area (e.g., spread fertilizer).
    *   Sense 8: move outward (e.g., soldiers fanned out).
    *   Sense 9: cover by spreading something over (e.g., spread bread with cheese).
    *   Sense 10: distribute over a surface in a layer (e.g., spread cheese on bread).

    *   The context is medical: "malignant (has spread... to other parts of the body)".
    *   This describes a process where a disease (cancer) moves and establishes itself in new areas.
    *   Sense 2 ("become distributed or widespread") specifically lists "the infection spread" as an example. Cancer metastasis is analogous to an infection spreading.
    *   Sense 3 ("spread across or over") is more about surface area (oil spot).
    *   Sense 8 ("move outward") is more about physical movement of people or objects (soldiers).

    *   Sense 2: "become distributed or widespread" | synonyms: propagate | examples: "the infection spread".
    *   This fits perfectly with the medical context of cancer spreading to other parts of the body.

currency: USD

source: unavailable


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: likely
Target surface form: likely
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=likely%3:00:00:: | definition=has a good chance of being the case or of coming about | examples=these services are likely to be available to us all before long; she is likely to forget
2. sense_key=likely%3:00:04:: | definition=likely but not certain to be or become true or real | synonyms=probable | examples=a likely result; he foresaw a probable loss
3. sense_key=likely%5:00:00:prospective:00 | definition=expected to become or be; in prospect | synonyms=potential | examples=potential clients
4. sense_key=likely%5:00:00:credible:00 | definition=within the realm of credibility | examples=not a very likely excuse

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `likely`
    *   Target surface form: `likely`
    *   Context: "...malignant (has spread, or is <t>likely</t> to spread easily, to other parts of the body)..."
    *   Candidate senses:
        1.  `likely%3:00:00::`: has a good chance of being the case or of coming about (e.g., "likely to be available", "likely to forget").
        2.  `likely%3:00:04::`: likely but not certain to be or become true or real (synonym: probable; e.g., "a likely result").
        3.  `likely%5:00:00:prospective:00`: expected to become or be; in prospect (synonym: potential; e.g., "potential clients").
        4.  `likely%5:00:00:credible:00`: within the realm of credibility (e.g., "not a very likely excuse").

    *   The phrase is "is likely to spread easily".
    *   This describes a probability or a chance that the cancer will spread.
    *   It fits the pattern "is likely to [verb]".

    *   Sense 1: "has a good chance of being the case or of coming about". Example: "she is likely to forget". This matches the grammatical structure ("is likely to spread") and the meaning (probability of an event occurring).
    *   Sense 2: "likely but not certain to be or become true or real". Synonym: "probable". Example: "a likely result". This is usually used as an adjective modifying a noun (attributive use).
    *   Sense 3: "expected to become or be; in prospect". Synonym: "potential". Example: "potential clients". This is also typically attributive.
    *   Sense 4: "within the realm of credibility". Example: "not a very likely excuse". This refers to plausibility, not probability of occurrence.

    *   The context "is likely to spread" is a predicative use of "likely" meaning "probable" or "having a good chance".
    *   Sense 1 specifically provides the example "she is likely to forget", which mirrors the structure "is likely to spread".

    *   Sense 1: "has a good chance of... coming about" -> "is likely to spread". (Perfect fit)
    *   Sense 2: "probable" (usually attributive, e.g., "a likely result").
    *   Sense 3: "potential" (attributive, e.g., "potential clients").
    *   Sense 4: "credible" (plausible).

    Sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spread
Target surface form: spread
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=spread%2:35:00:: | definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. sense_key=spread%2:35:07:: | definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
3. sense_key=spread%2:42:00:: | definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
4. sense_key=spread%2:35:03:: | definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
5. sense_key=spread%2:32:00:: | definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. sense_key=spread%2:32:02:: | definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. sense_key=spread%2:38:00:: | definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. sense_key=spread%2:38:02:: | definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. sense_key=spread%2:35:12:: | definition=cover by spreading something over | examples=spread the bread with cheese
10. sense_key=spread%2:35:13:: | definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `spread`
    *   Target surface form: `spread`
    *   Context: "...malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body)..."
    *   Meaning: In the context of cancer (malignancy), "spread" refers to the movement of cancer cells from the primary site to other parts of the body (metastasis).

    *   Sense 1: distribute or disperse widely (active, e.g., invaders spreading language).
    *   Sense 2: become distributed or widespread (intransitive, e.g., infection spread, optimism spread).
    *   Sense 3: spread across or over (e.g., oil spot spread across water).
    *   Sense 4: spread out or open from a closed state (e.g., open the map).
    *   Sense 5: cause to become widely known (e.g., spread information).
    *   Sense 6: become widely known and passed on (e.g., rumor spread).
    *   Sense 7: strew or distribute over an area (e.g., spread fertilizer).
    *   Sense 8: move outward (e.g., soldiers fanned out).
    *   Sense 9: cover by spreading something over (e.g., spread bread with cheese).
    *   Sense 10: distribute over a surface in a layer (e.g., spread cheese on bread).

    *   The context is medical: cancer spreading to other parts of the body.
    *   This is an intransitive use (the cancer spreads).
    *   Sense 2 ("become distributed or widespread") specifically lists "the infection spread" as an example. Cancer metastasis is very similar to an infection spreading throughout the body.
    *   Sense 3 ("spread across or over") is more about surface area (oil spot).
    *   Sense 8 ("move outward") is more about physical movement of a group (soldiers).

    *   Sense 2: "become distributed or widespread" | synonyms: propagate | examples: "the infection spread".
    *   This fits perfectly with the medical context of cancer cells moving and establishing themselves in other parts of the body.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: easily
Target surface form: easily
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=easily%4:02:01:: | definition=with ease (`easy' is sometimes used informally for `easily') | synonyms=easy | examples=she was easily excited; was easily confused
2. sense_key=easily%4:02:06:: | definition=without question | examples=easily the best book she's written
3. sense_key=easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "easily"
    *   Target surface form: "easily"
    *   Context: "...malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body)..."
    *   Candidate senses:
        1.  `easily%4:02:01::`: with ease (e.g., "easily excited", "easily confused").
        2.  `easily%4:02:06::`: without question (e.g., "easily the best book").
        3.  `easily%4:02:05::`: indicating high probability; in all likelihood (e.g., "could easily have ended in disaster").

    *   The phrase is "likely to spread easily".
    *   "Spread easily" in a medical context (cancer metastasis) means that the process of spreading happens with little resistance or effort, or is a characteristic of the disease's nature (it doesn't require much for it to happen).
    *   Let's compare the senses:
        *   Sense 1: "with ease". If cancer spreads "easily", it means it does so without much difficulty/resistance. This fits the general meaning of "easily" as an adverb of manner.
        *   Sense 2: "without question". "Likely to spread without question" doesn't fit the grammatical structure or the meaning here.
        *   Sense 3: "indicating high probability; in all likelihood". "Likely to spread in all likelihood" is redundant ("likely" and "easily" both meaning probability).

    *   "Likely to spread easily"
    *   "Likely" already covers the probability aspect.
    *   "Easily" describes *how* it spreads (with ease, without much resistance).
    *   Example from Sense 1: "she was easily excited" (it didn't take much to excite her). Similarly, "cancer spreads easily" (it doesn't take much for it to spread).

    *   Sense 1: with ease. (Correct)
    *   Sense 2: without question. (Incorrect)
    *   Sense 3: high probability. (Incorrect, as "likely" is already present).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "other"
    *   Target surface form: "other"
    *   Context: "...malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body)..."
    *   Candidate senses:
        1.  `other%3:00:00::`: not the same one or ones already mentioned or implied.
        2.  `other%5:00:00:past:00`: recently past.
        3.  `other%5:00:02:past:00`: belonging to the distant past.
        4.  `other%5:00:00:strange:00`: very unusual; different in character or quality from the normal or expected.

    *   The phrase is "other parts of the body".
    *   In this context, "other" refers to parts of the body that are different from the original site of the cancer (the lungs/pleural mesothelioma).
    *   It means "additional" or "different from the one already mentioned".

    *   Sense 1: "not the same one or ones already mentioned or implied". This fits perfectly. The "parts of the body" are not the same as the original site of the cancer.
    *   Sense 2: "recently past". Does not fit.
    *   Sense 3: "belonging to the distant past". Does not fit.
    *   Sense 4: "very unusual". Does not fit.

    *   Sense 1 is the only one that makes sense in the context of "other parts of the body".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: parts
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 5}
```

content:
```json
{"sense_index": 5}
```

reasoning_content:
*   Target lemma: `part`
    *   Target surface form: `parts`
    *   Context: "...malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body)..."

    *   Sense 1: something determined in relation to something that includes it (portion, component part).
    *   Sense 2: something less than the whole of a human artifact (portion).
    *   Sense 3: a portion of a natural object (piece).
    *   Sense 4: that which concerns a person with regard to a particular role or situation.
    *   Sense 5: the extended spatial location of something (region).
    *   Sense 6: actions and activities assigned to or required of a person or group (function, role).
    *   Sense 7: an actor's portrayal (character, role).
    *   Sense 8: assets belonging to or due to an individual (share, portion).
    *   Sense 9: one of the portions into which something is regarded as divided (section, division).
    *   Sense 10: a line of scalp (parting).
    *   Sense 11: melody carried by a particular voice (voice).
    *   Sense 12: the part played by a person in bringing about a result (contribution).

    *   The phrase is "other parts of the body".
    *   The "body" is a natural object.
    *   "Parts of the body" refers to regions or portions of the body.

    *   Sense 3: "a portion of a natural object" (synonym: piece). Example: "they analyzed the river into three parts".
    *   Sense 5: "the extended spatial location of something" (synonym: region). Example: "the farming regions of France; religions in all parts of the world".
    *   Sense 9: "one of the portions into which something is regarded as divided and which together constitute a whole" (synonym: section, division). Example: "the written part of the exam".

    *   Sense 5 ("the extended spatial location of something", synonym "region") fits very well with "parts of the body" (meaning different regions of the body).
    *   Sense 3 ("a portion of a natural object") is also a possibility, but "parts of the body" usually refers to regions/areas rather than "pieces" (which implies something broken off or a discrete physical chunk).
    *   Sense 9 ("one of the portions into which something is regarded as divided") is more about conceptual or structural divisions (like sections of an exam).

    *   "parts of the world" (Sense 5) is very similar to "parts of the body".
    *   "parts of the body" refers to regions/areas.

    *   Sense 5: "the extended spatial location of something" | synonyms=region | examples=the farming regions of France; religions in all parts of the world.
    *   This matches "parts of the body" perfectly.

    *   Sense 3: "a portion of a natural object" | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite. (This feels more like a physical piece/fragment).
    *   Sense 9: "one of the portions into which something is regarded as divided" | synonyms=section, division. (This is more about logical or structural division).

    Sense 5 is the best fit for "parts of the body" in the context of cancer spreading to other regions.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: "body"
    *   Target surface form: "body"
    *   Context: "...malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>)..."
    *   The context is medical, discussing cancer (pleural mesothelioma, non-small cell lung cancer) and its spread (metastasis) to other parts of the human body.

    *   Sense 1: "the entire structure of an organism (an animal, plant, or human being)" - Fits perfectly.
    *   Sense 2: "a group of persons associated by some common tie..." - Doesn't fit.
    *   Sense 3: "a natural object consisting of a dead animal or person" - Doesn't fit (the patient is alive).
    *   Sense 4: "an individual 3-dimensional object that has mass..." - Too general (usually used for physics/astronomy).
    *   Sense 5: "the body excluding the head and neck and limbs" (torso) - Too specific; cancer spreads to the whole body, not just the torso.
    *   Sense 6: "a collection of particulars considered as a system" - Doesn't fit.
    *   Sense 7: "the property of holding together and retaining its shape" - Doesn't fit.
    *   Sense 8: "the central message of a communication" - Doesn't fit.
    *   Sense 9: "the main mass of a thing" - Too general.
    *   Sense 10: "a resonating chamber in a musical instrument" - Doesn't fit.
    *   Sense 11: "the external structure of a vehicle" - Doesn't fit.

    *   The context refers to the human body as a biological organism.
    *   Sense 1 ("the entire structure of an organism") is the most accurate description.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical description of the drug Alimta, mentioning its use in "patients who have not received chemotherapy" and "patients who have not been treated before".
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The context is clearly medical: "Alimta is used to treat two types of cancer... in patients who have not received chemotherapy".
    *   The word "patients" refers to the people receiving the medical treatment (Alimta).

    *   Sense 1: "a person who requires medical care" - This fits perfectly.
    *   Sense 2: "the semantic role of an entity..." - This is a linguistic term (patient role in grammar), which is completely irrelevant to the medical context.

    *   The correct sense is Sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicines
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicines`
    *   Context: "...patients who have not received chemotherapy (<t>medicines</t> for cancer) before..."
    *   Candidate senses:
        1.  `medicine%1:09:00::`: branches of medical science (medical specialty).
        2.  `medicine%1:06:00::`: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).
        3.  `medicine%1:04:00::`: the learned profession (practice of medicine).
        4.  `medicine%1:04:02::`: punishment for one's actions (take your medicine).

    *   The sentence says "chemotherapy (medicines for cancer)".
    *   Chemotherapy consists of drugs/medications used to treat cancer.
    *   This matches the definition of "something that treats or prevents or alleviates the symptoms of disease" (medication, medicinal drug).

    *   Sense 1: Medical specialty (e.g., cardiology). Not applicable.
    *   Sense 2: Medication/drug. Fits perfectly.
    *   Sense 3: The profession/study of medicine. Not applicable.
    *   Sense 4: Punishment. Not applicable.

    *   The best sense is index 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `cancer`
    *   Target surface form: `cancer`
    *   Context: A medical description of the drug Alimta, used to treat "two types of cancer: pleural mesothelioma", "anticancer medicine", "malignant", "chemotherapy (medicines for <t>cancer</t>)".
    *   Candidate senses:
        1.  `cancer%1:26:00::`: malignant growth or tumor caused by abnormal and uncontrolled cell division.
        2.  `cancer%1:18:00::`: (astrology) person born while the sun is in Cancer.
        3.  `cancer%1:17:00::`: zodiacal constellation.
        4.  `cancer%1:15:00::`: fourth sign of the zodiac.
        5.  `cancer%1:05:00::`: type genus of the family Cancridae.

    *   The context is clearly medical, discussing a drug (Alimta), chemotherapy, malignant growths, and lung cancer.
    *   Sense 1 describes a malignant growth or tumor, which fits perfectly.
    *   Senses 2, 3, and 4 are astrological/astronomical.
    *   Sense 5 is biological (genus of crabs).

    *   Sense 1 is the only one that fits the medical context.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: advanced
Target surface form: advanced
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=advanced%5:00:00:precocious:00 | definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average
2. sense_key=advanced%5:00:00:late:02 | definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
3. sense_key=advanced%5:00:00:progressive:01 | definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
4. sense_key=advanced%5:00:02:high:02 | definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
5. sense_key=advanced%5:00:00:high-tech:00 | definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
6. sense_key=advanced%5:00:00:late:00 | definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
7. sense_key=advanced%5:00:00:civilized:00 | definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
8. sense_key=advanced%5:00:00:front:00 | definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `advanced`
    *   Target surface form: `advanced`
    *   Context: "...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells."
    *   Wait, looking closer at the context: "...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer..."
    *   Actually, the sentence structure seems slightly garbled in the provided text: "...in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer..."
    *   Wait, let me re-read: "Alimta is used together with cisplatin... in patients who have not received chemotherapy (medicines for cancer) before [for] advanced or metastatic non-small cell lung cancer..." (The word "for" seems missing, but the meaning is clear: it's describing the stage of the cancer).

    *   Sense 1: precocious (physical/mental development in children) - No.
    *   Sense 2: late (comparatively late in a course of development, e.g., "illness had reached an advanced stage") - Yes, this fits medical contexts where a disease has progressed.
    *   Sense 3: progressive (ahead of the times, innovative) - No.
    *   Sense 4: high (higher level in training/knowledge) - No.
    *   Sense 5: high-tech (complex/intricate technology) - No.
    *   Sense 6: late (far along in time, e.g., "advanced age") - No.
    *   Sense 7: civilized (highly developed societies) - No.
    *   Sense 8: front (situated ahead) - No.

    *   The context is "advanced or metastatic non-small cell lung cancer".
    *   "Advanced" here refers to the stage of the cancer (it has progressed significantly).
    *   Sense 2: "comparatively late in a course of development" with the example "the illness had reached an advanced stage". This is a perfect match.

    *   Sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "cell"
    *   Target surface form: "cell"
    *   Context: "...advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells."
    *   Candidate senses:
        1.  Small compartment (honeycomb).
        2.  (Biology) Basic structural and functional unit of all organisms.
        3.  Electric current device (battery).
        4.  Political movement unit (cadre).
        5.  Mobile phone.
        6.  Monk/nun room.
        7.  Prisoner room.

    *   The context discusses "non-small cell lung cancer" and "squamous cells."
    *   This is clearly a medical/biological context referring to the biological units that make up tissues in the body.

    *   Sense 2: "(biology) the basic structural and functional unit of all organisms..." matches perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `affect`
    *   Target surface form: `affecting`
    *   Context: "...advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells."
    *   Meaning: The cancer is not impacting or involving the squamous cells.

    *   Sense 1: `have an effect upon` (general impact). Example: "Will the new rules affect me?"
    *   Sense 2: `act physically on; have an effect upon`. Example: "the medicine affects my heart rate".
    *   Sense 3: `connect closely and often incriminatingly` (synonyms: involve, regard). Example: "This new ruling affects your business".
    *   Sense 4: `make believe with the intent to deceive` (feign).
    *   Sense 5: `have an emotional or cognitive impact upon` (impress, move).

    *   The context is medical: "non-small cell lung cancer that is not affecting the squamous cells."
    *   In medical terminology, when a disease "affects" an organ or cell type, it means it is present in, involves, or acts physically upon that part of the body.
    *   Sense 2 ("act physically on; have an effect upon") specifically mentions medicine affecting heart rate, which is a physical/biological effect.
    *   Sense 1 is more general.
    *   Sense 3 ("connect closely and often incriminatingly") is more about legal or business involvement.
    *   Sense 4 and 5 are completely irrelevant.

    *   Sense 1: General effect.
    *   Sense 2: Physical/biological effect.
    *   In the context of cancer "affecting" cells, it is a physical/biological process. Sense 2 is the most precise fit for medical/biological contexts.

    *   Wait, let me re-read Sense 2: "act physically on; have an effect upon".
    *   Let me re-read Sense 1: "have an effect upon".
    *   Usually, in medical contexts (disease affecting an organ), it means the disease is present in or impacting that organ.
    *   Comparing Sense 1 and Sense 2: Sense 2 is more specific to physical/biological action.

    *   "non-small cell lung cancer that is not affecting the squamous cells."
    *   This means the cancer does not involve or impact the squamous cells.
    *   Sense 2: "act physically on; have an effect upon" (Example: medicine affects heart rate).
    *   Sense 1: "have an effect upon" (Example: rules affect me).
    *   Sense 2 is clearly the intended meaning for biological/medical impact.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `use`
    *   Target surface form: `used`
    *   Context: "Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before..."
    *   General context: A medical description of a drug (Alimta) and its application for treating cancer.

    *   Sense 1: `put into service; make work or employ for a particular purpose or for its inherent or natural purpose` (Synonyms: utilize, utilise, apply, employ).
    *   Sense 2: `take or consume (regularly or habitually)` (Synonyms: habituate).
    *   Sense 3: `use up, consume fully` (Synonyms: expend).
    *   Sense 4: `seek or achieve an end by using to one's advantage`.
    *   Sense 5: `avail oneself to` (Synonyms: practice, apply).
    *   Sense 6: `habitually do something (use only in the past tense)`.

    *   The sentence is: "Alimta is used in combination with cisplatin..."
    *   This means Alimta is *employed* or *utilized* as a treatment.
    *   It is not about consuming a drug habitually (Sense 2), using it up (Sense 3), using someone/something to one's advantage (Sense 4), practicing a religion/principle (Sense 5), or a past habit (Sense 6).
    *   Sense 1 fits perfectly: "put into service; make work or employ for a particular purpose". In this case, the purpose is treating cancer.

    *   Sense 1: "put into service; make work or employ for a particular purpose" -> Alimta is employed for the purpose of treating cancer. (Correct)
    *   Sense 2: "take or consume (regularly or habitually)" -> This usually refers to the *person* using the drug (e.g., "He uses Alimta"), not the drug being used. (Incorrect)
    *   Sense 3: "use up, consume fully" -> Not applicable. (Incorrect)
    *   Sense 4: "seek or achieve an end by using to one's advantage" -> This usually implies manipulation or strategic use of a person or resource. (Incorrect)
    *   Sense 5: "avail oneself to" -> Not applicable. (Incorrect)
    *   Sense 6: "habitually do something (past tense)" -> Not applicable. (Incorrect)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical description of the drug Alimta, mentioning its use in treating cancer in "patients who have not received chemotherapy" and "patients who have not been treated before".
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The context is clearly medical ("Alimta", "cancer", "chemotherapy", "prescription").
    *   The word "patients" refers to the people receiving the treatment.
    *   Sense 1 describes a person requiring medical care.
    *   Sense 2 describes a linguistic/semantic role (the "patient" in a sentence).

    *   Sense 1 is the correct fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treated
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
*   Target lemma: `treat`
    *   Target surface form: `treated`
    *   Context: "Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past."
    *   Domain: Medical/Pharmaceutical (cancer treatment).

    *   Sense 1: interact in a certain way (handle, do by) - *Incorrect*
    *   Sense 2: subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition (process) - *Often used for materials (e.g., treated wood, processed cheese).*
    *   Sense 3: provide treatment for (care for) - *Used for medical treatment of patients.*
    *   Sense 4: act on verbally or in some form of artistic expression (cover, handle) - *Incorrect*
    *   Sense 5: provide with a gift or entertainment - *Incorrect*
    *   Sense 6: provide with choice or abundant food or drink (regale) - *Incorrect*
    *   Sense 7: engage in negotiations - *Incorrect*
    *   Sense 8: regard or consider in a specific way - *Incorrect*

    *   The context refers to patients receiving chemotherapy for cancer.
    *   "patients who have not been treated before" means patients who have not received medical treatment for their condition.
    *   Sense 3 ("provide treatment for") fits perfectly. Sense 2 ("subject to a process") is more about industrial or chemical processing of materials, though it mentions "remedying a condition," the primary medical sense for patients is Sense 3.

    *   Sense 3: "provide treatment for" / "care for" / "The doctor treated my broken leg".
    *   This matches the context of patients receiving cancer medication.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `patient`
    *   Target surface form: `patients`
    *   Context: A medical text describing the use of the drug Alimta for treating cancer. The specific sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past."
    *   Candidate senses:
        1.  `patient%1:18:00::`: a person who requires medical care.
        2.  `patient%1:10:00::`: the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause.

    *   The word "patients" refers to people receiving treatment (chemotherapy) for cancer.
    *   This clearly aligns with the definition "a person who requires medical care."
    *   It does not refer to a linguistic/semantic role (the "patient" role in grammar).

    *   Sense 1: Medical patient. (Correct)
    *   Sense 2: Linguistic patient role. (Incorrect)


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `type`
    *   Target surface form: `type`
    *   Context: "...and on its own in patients who have received another <t>type</t> of chemotherapy in the past."
    *   Candidate senses:
        1.  `type%1:09:00::`: a subdivision of a particular kind of thing (e.g., "what type of sculpture do you prefer?")
        2.  `type%1:18:00::`: a person of a specified kind (usually with many eccentricities)
        3.  `type%1:14:01::`: (biology) the taxonomic group whose characteristics are used to define the next higher taxon
        4.  `type%1:10:01::`: printed characters
        5.  `type%1:10:00::`: all of the tokens of the same symbol
        6.  `type%1:06:00::`: a small metal block bearing a raised character on one end

    *   The sentence is: "...and on its own in patients who have received another type of chemotherapy in the past."
    *   Here, "type of chemotherapy" refers to a category or kind of chemotherapy treatment.

    *   Sense 1: "a subdivision of a particular kind of thing" - This fits perfectly. Chemotherapy is the "kind of thing," and there are different "types" (subdivisions) of it.
    *   Sense 2: "a person of a specified kind" - Incorrect.
    *   Sense 3: "(biology) the taxonomic group..." - Incorrect.
    *   Sense 4: "printed characters" - Incorrect.
    *   Sense 5: "all of the tokens of the same symbol" - Incorrect.
    *   Sense 6: "a small metal block..." - Incorrect.

    *   The word "type" in "another type of chemotherapy" clearly means a category or variety. Sense 1 is the only one that matches this meaning.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
*   Target lemma: `past`
    *   Target surface form: `past`
    *   Context: "...and on its own in patients who have received another type of chemotherapy in the <t>past</t>."
    *   Candidate senses:
        1.  `past%1:28:00::`: the time that has elapsed (synonyms: past times, yesteryear; example: forget the past).
        2.  `past%1:28:01::`: an earlier period in someone's life (especially one that they have reason to keep secret) (example: reporters dug into the candidate's past).
        3.  `past%1:10:00::`: a verb tense that expresses actions or states in the past (synonyms: past tense).

    *   The sentence is: "...patients who have received another type of chemotherapy in the past."
    *   "In the past" here refers to a time before the current moment, specifically referring to the medical history of the patients.

    *   Sense 3 (verb tense) is completely irrelevant.
    *   Sense 2 (earlier period in someone's life, often secret) is too specific and carries a connotation of secrets/scandals ("reporters dug into..."). While it is an earlier period in their life, it's not used in the "secret" or "personal history" sense here; it's a general temporal reference.
    *   Sense 1 (the time that has elapsed) fits best. "In the past" is a common idiom meaning "at some time or times before now."

    *   Sense 1: "the time that has elapsed" -> "in the past" (at a previous time).
    *   Sense 2: "a earlier period in someone's life (especially one that they have reason to keep secret)" -> Not applicable.
    *   Sense 3: "a verb tense" -> Not applicable.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: `medicine`
    *   Target surface form: `medicine`
    *   Context: "It contains the active substance pemetrexed... Alimta is used to treat two types of cancer... Alimta is used together with cisplatin (another anticancer medicine)... The <t>medicine</t> can only be obtained with a prescription."
    *   Candidate senses:
        1.  `medicine%1:09:00::`: branches of medical science (medical specialty).
        2.  `medicine%1:06:00::`: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug).
        3.  `medicine%1:04:00::`: the learned profession (practice of medicine).
        4.  `medicine%1:04:02::`: punishment for one's actions (take your medicine).

    *   The context discusses "Alimta", a substance containing "pemetrexed", used to treat cancer.
    *   It mentions "another anticancer medicine" (referring to cisplatin).
    *   It states "The <t>medicine</t> can only be obtained with a prescription."
    *   This clearly refers to a drug or medication.

    *   Sense 1: Medical science/specialty (Incorrect).
    *   Sense 2: Medication/medicinal drug (Correct).
    *   Sense 3: Medical profession (Incorrect).
    *   Sense 4: Punishment (Incorrect).

    *   The best fit is sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
*   Target lemma: "only"
    *   Target surface form: "only"
    *   Context: "The medicine can <t>only</t> be obtained with a prescription."

    *   Sense 1: "and nothing more" (merely, simply, just, but) - e.g., "I was merely asking."
    *   Sense 2: "without any others being included or involved" (entirely, exclusively, solely, alone) - e.g., "was entirely to blame."
    *   Sense 3: "with nevertheless the final result" - e.g., "He arrived only to find his wife dead."
    *   Sense 4: "in the final outcome" - e.g., "These news will only make you more upset."
    *   Sense 5: "except that" - e.g., "It was the same story; only this time she came out better."
    *   Sense 6: "never except when" (only if, only when) - e.g., "call me only if your cold gets worse."
    *   Sense 7: "as recently as" - e.g., "I spoke to him only an hour ago."

    *   "The medicine can only be obtained with a prescription."
    *   This means the medicine is obtained *exclusively* with a prescription, or *never except when* there is a prescription.
    *   Let's compare Sense 2 and Sense 6.
        *   Sense 2: "without any others being included or involved" (exclusively, solely). "The medicine can exclusively be obtained with a prescription." (Fits well).
        *   Sense 6: "never except when" (only if, only when). "The medicine can be obtained only if there is a prescription." (Fits very well).

    *   Wait, let's look at the phrasing again: "can <t>only</t> be obtained with a prescription."
    *   Is it "exclusively" (Sense 2) or "never except when" (Sense 6)?
    *   Sense 6 is often used as a conjunction or in a conditional clause ("only if", "only when"). In the sentence "The medicine can only be obtained with a prescription," "only" is an adverb modifying the verb phrase "be obtained with a prescription."
    *   Let's re-examine Sense 2: "without any others being included or involved" (exclusively, solely).
    *   Let's re-examine Sense 1: "and nothing more" (merely, simply, just). "The medicine can just be obtained with a prescription" (Doesn't fit the meaning).

    *   Let's look at Sense 2 again: "without any others being included or involved" (synonyms: entirely, exclusively, solely, alone).
    *   If we substitute "exclusively": "The medicine can exclusively be obtained with a prescription." This makes sense.
    *   If we substitute "solely": "The medicine can solely be obtained with a prescription." This also makes sense.

    *   Let's look at Sense 6 again: "never except when" (synonyms: only if, only when).
    *   "The medicine can [never except when] be obtained with a prescription." This doesn't fit the grammatical structure as well as Sense 2 does, although the *meaning* is similar. Sense 6 is usually used as "only if" or "only when".

    *   Wait, let's look at the examples for Sense 2: "was entirely to blame; a school devoted entirely to the needs of problem children". These are about exclusivity.
    *   Let's look at the examples for Sense 6: "call me only if your cold gets worse". This is a conditional.

    *   In "The medicine can only be obtained with a prescription," "only" restricts the condition under which the medicine can be obtained.
    *   Is it "exclusively" (Sense 2) or "never except when" (Sense 6)?
    *   Actually, "only" in "can only be obtained with a prescription" is often categorized as "solely" or "exclusively".

    *   Let's double-check Sense 2 again: "without any others being included or involved".
    *   If the only way to get the medicine is with a prescription, then no other ways are involved.

    *   Let's check Sense 1: "and nothing more" (merely, simply, just). "The medicine can merely be obtained with a prescription." (No).

    *   Let's re-evaluate Sense 6: "never except when". "The medicine can [only] be obtained with a prescription." This is essentially saying "The medicine can be obtained only if you have a prescription."

    *   Comparing Sense 2 (exclusively) and Sense 6 (never except when):
        Sense 2: "The medicine can exclusively be obtained with a prescription."
        Sense 6: "The medicine can be obtained only if you have a prescription."

    *   In the sentence "The medicine can only be obtained with a prescription," "only" is an adverb. Sense 2's synonyms (exclusively, solely) are adverbs. Sense 6's synonyms (only if, only when) are conjunctions.

    *   Therefore, Sense 2 is the better fit grammatically and semantically.

    *   Wait, let me look at Sense 2 again. "without any others being included or involved".
    *   Example: "was entirely to blame" (no one else was to blame).
    *   Example: "a school devoted entirely to the needs of problem children" (no other needs were the focus).
    *   In "The medicine can only be obtained with a prescription," the "only" modifies the condition "with a prescription." It means no other condition (like buying it over the counter) is possible. This fits "exclusively" or "solely".

    *   Let's check Sense 6 again. "never except when". Example: "call me only if your cold gets worse". This is a conditional. "The medicine can only be obtained with a prescription" is also a conditional statement (If you obtain the medicine, then you must have a prescription).

    *   However, "only" in "can only be obtained" is an adverb. Sense 2's synonyms (exclusively, solely) are adverbs. Sense 6's synonyms (only if, only when) are conjunctions.

    *   Let's re-read Sense 2: "without any others being included or involved".
    *   Let's re-read Sense 6: "never except when".

    *   If I say "I only eat vegetables," does that mean "I exclusively eat vegetables" (Sense 2) or "I eat vegetables never except when..." (Sense 6)? It means "I exclusively eat vegetables."

    *   Similarly, "The medicine can only be obtained with a prescription" means "The medicine can exclusively be obtained with a prescription."

    *   Sense 2 seems the most accurate.

    *   Sense 1: merely/simply (No)
    *   Sense 2: exclusively/solely (Yes)
    *   Sense 3: nevertheless (No)
    *   Sense 4: final outcome (No)
    *   Sense 5: except that (No)
    *   Sense 6: only if/only when (No, this is usually a conjunction)
    *   Sense 7: as recently as (No)

    *   Wait, let me double-check Sense 6 one more time. "never except when".
    *   "The medicine can only be obtained with a prescription."
    *   Could "only" here be a shortened form of "only if it is"?
    *   "The medicine can [only] be obtained with a prescription."
    *   If we replace "only" with "solely": "The medicine can solely be obtained with a prescription." (Correct)
    *   If we replace "only" with "exclusively": "The medicine can exclusively be obtained with a prescription." (Correct)

    *   Let's look at Sense 2 again. "without any others being included or involved".
    *   In this case, "others" would be "other ways of obtaining the medicine".

    *   Let's look at Sense 6 again. "never except when".
    *   "The medicine can [never except when] be obtained with a prescription." (This doesn't quite work grammatically).

    *   Therefore, Sense 2 is the strongest candidate.