[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: delay
Target surface form: delayed
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be <t>delayed</t> or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=delay%2:30:00:: | definition=cause to be slowed down or delayed | synonyms=detain, hold up | examples=Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform
2. sense_key=delay%2:42:00:: | definition=act later than planned, scheduled, or required | examples=Don't delay your application to graduate school or else it won't be considered
3. sense_key=delay%2:30:01:: | definition=stop or halt | synonyms=stay, detain | examples=Please stay the bloodshed!
4. sense_key=delay%2:30:05:: | definition=slow the growth or development of | synonyms=check, retard | examples=The brain damage will retard the child's language development

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "delayed" in the context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
The context is about medical treatment (Alimta).
The treatment should be delayed (slowed down, postponed, held up) or discontinued.
Let's look at the candidate senses:
1. sense_key=delay%2:30:00:: | definition=cause to be slowed down or delayed | synonyms=detain, hold up | examples=Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform
2. sense_key=delay%2:42:00:: | definition=act later than planned, scheduled, or required | examples=Don't delay your application to graduate school or else it won't be considered
3. sense_key=delay%2:30:01:: | definition=stop or halt | synonyms=stay, detain | examples=Please stay the bloodshed!
4. sense_key=delay%2:30:05:: | definition=slow the growth or development of | synonyms=check, retard | examples=The brain damage will retard the child's language development

In the context, "Treatment should be delayed" means the treatment is postponed or held up.
Sense 1: "cause to be slowed down or delayed" (detain, hold up). This fits "Treatment should be delayed" (held up, postponed).
Wait, "delay" as a transitive verb here: "Treatment should be delayed" (passive).
Sense 1: cause to be slowed down or delayed.
Sense 2: act later than planned, scheduled, or required. (Intransitive or transitive, but usually "delay your application").
Sense 1 fits "hold up" or "postpone".
Let's check the examples for Sense 1: "Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform".
In the context, "Treatment should be delayed" means the administration of the treatment is held up or postponed.
Sense 1 is the best fit.
Let's double check Sense 1 vs Sense 2.
Sense 1: cause to be slowed down or delayed.
Sense 2: act later than planned, scheduled, or required.
"delayed" in "Treatment should be delayed" is passive. The doctor delays the treatment. The doctor causes the treatment to be slowed down or delayed.
Therefore, Sense 1 is the most appropriate.
Wait, let's look at the synonyms for Sense 1: detain, hold up.
Synonyms for Sense 2: none listed, but "act later than planned".
"hold up" fits "delayed" in medical context (e.g., treatment is held up).
I will choose Sense 1.
Let's review the options.
1. sense_key=delay%2:30:00::
2. sense_key=delay%2:42:00::
3. sense_key=delay%2:30:01::
4. sense_key=delay%2:30:05::

Sense 1 is the best.
Context: "Treatment should be delayed or discontinued..."
This means the treatment is held up.
I will output {"sense_index": 1}.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: discontinue
Target surface form: discontinued
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or <t>discontinued</t>, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=discontinue%2:42:00:: | definition=put an end to a state or an activity | synonyms=stop, cease, give up, quit, lay off | examples=Quit teasing your little brother
2. sense_key=discontinue%2:42:01:: | definition=come to or be at an end | examples=the support from our sponsoring agency will discontinue after March 31
3. sense_key=discontinue%2:30:00:: | definition=prevent completion | synonyms=break, break off, stop | examples=stop the project; break off the negotiations

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
The target word is "discontinued" in the context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
The context is about stopping a medical treatment (an activity or state).
Sense 1: put an end to a state or an activity (stop, cease, give up, quit, lay off). Example: Quit teasing your little brother.
Sense 2: come to or be at an end. Example: the support from our sponsoring agency will discontinue after March 31.
Sense 3: prevent completion (break, break off, stop). Example: stop the project; break off the negotiations.

In the context, "Treatment should be delayed or discontinued" means to put an end to the treatment (an activity).
Sense 1 fits best: "put an end to a state or an activity".
Let's double check.
"discontinue" as a transitive verb here: "Treatment should be delayed or discontinued [by the doctor]".
Sense 1 is transitive: "put an end to a state or an activity".
Sense 2 is intransitive: "come to or be at an end".
Sense 3 is transitive: "prevent completion".
"discontinue treatment" means to stop the treatment. Sense 1 is the best fit.
Let's review the examples for Sense 1: "Quit teasing your little brother".
Synonyms: stop, cease, give up, quit, lay off.
Yes, "stop" or "cease" treatment.
Therefore, sense 1.
End of thought.

format: unknown

native_finish_reason: stop

provider: Alibaba

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the <t>dose</t> reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "dose".
Context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
The context is about the amount of medicine (Alimta, cisplatin) given to a patient.
Sense 1: a measured portion of medicine taken at any one time.
Sense 2: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
Wait, let's look at the context: "the dose reduced". This refers to the measured portion of medicine.
Is it sense 1 or sense 2?
Sense 1: a measured portion of medicine taken at any one time.
Sense 2: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
In WordNet, "dose" as a measured portion of medicine is sense 1.
Let's check the context again: "the recommended dose of Alimta is 500 mg... the dose reduced". This is a measured portion of medicine.
Wait, "dose" in WordNet:
dose%1:06:00:: a measured portion of medicine taken at any one time
dose%1:23:00:: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time
Actually, "dose" in the context of "the dose reduced" refers to the measured portion of medicine.
Let's see: "a measured portion of medicine taken at any one time" fits perfectly.
Let's consider "dose" in WordNet.
Sense 1: a measured portion of medicine taken at any one time.
Sense 2: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
Is there a difference? "medicine" vs "active agent". Alimta is a medicine.
I will choose sense 1.
Wait, let's look at the synonyms: dosage. Both have dosage.
But "measured portion of medicine" is exactly what "dose" means here.
Let's choose 1.
Wait, let's re-read carefully: "the dose reduced".
Sense 1: a measured portion of medicine taken at any one time.
I'll go with 1.
Let's double check if there's any other nuance. "dose" of Alimta. Alimta is a medicine.
So sense 1 is the best fit.
Another option: "dose" as in "quantity of an active agent". But "medicine" is more specific and fits "Alimta".
I will output 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduced
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose <t>reduced</t>, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question
3. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
4. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
5. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
6. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
7. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
8. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
9. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
10. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
11. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
12. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
13. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
14. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
15. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
16. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
17. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
18. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
19. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
20. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "Treatment should be delayed or discontinued, or the dose <t>reduced</t>, in patients whose blood counts are abnormal or who have certain other side effects."
The target word is "reduced".
The context talks about reducing the dose of a medicine.
Sense 1: cut down on; make a reduction in. Examples: reduce your daily fat intake; The employer wants to cut back health benefits.
Sense 8: lessen and make more modest. Examples: reduce one's standard of living.
Sense 9: make smaller. Examples: reduce an image.
Sense 1: "cut down on; make a reduction in" fits "reduce the dose".
Let's check the examples for sense 1: "reduce your daily fat intake". This is very similar to "reduce the dose".
Wait, sense 1 is "cut down on; make a reduction in".
Is there a better sense?
Sense 1: reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits.
Yes, "reduce the dose" means to cut down on the dose, make a reduction in the dose.
Let's double check.
"reduce the dose" -> cut down on the dose.
Sense 1 is the best fit.
Let's review the options.
1. cut down on; make a reduction in
8. lessen and make more modest
9. make smaller
19. lessen the strength or flavor of a solution or mixture
"reduce the dose" is a standard medical phrase meaning to cut down on the amount.
Sense 1 is the most appropriate.
I will output {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in <t>patients</t> whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "patients" in the context of medical treatment ("Alimta should only be given under the supervision of a doctor...", "calculated using the patient's height and weight", "patients should take a corticosteroid", "patients whose blood counts are abnormal").
The candidate senses are:
1. a person who requires medical care
2. the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause

The context clearly refers to people receiving medical care (patients of a doctor, taking medication, having blood counts, kidney problems).
Therefore, sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: blood_count
Target surface form: blood counts
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose <t>blood counts</t> are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=blood_count%1:23:00:: | definition=the number of red and white corpuscles in a blood sample
2. sense_key=blood_count%1:04:00:: | definition=the act of estimating the number of red and white corpuscles in a blood sample

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "blood counts" in the context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
The context refers to the number of red and white corpuscles in a blood sample, which is a measurable quantity (the number itself), not the act of estimating.
Sense 1: the number of red and white corpuscles in a blood sample.
Sense 2: the act of estimating the number of red and white corpuscles in a blood sample.
"whose blood counts are abnormal" refers to the number being abnormal, not the act of estimating.
Therefore, Sense 1 is the best fit.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: abnormal
Target surface form: abnormal
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are <t>abnormal</t> or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=abnormal%3:00:00:: | definition=not normal; not typical or usual or regular or conforming to a norm | synonyms=unnatural | examples=abnormal powers of concentration; abnormal amounts of rain
2. sense_key=abnormal%3:00:03:: | definition=departing from the normal in e.g. intelligence and development | examples=they were heartbroken when they learned their child was abnormal; an abnormal personality
3. sense_key=abnormal%5:00:00:immoderate:00 | definition=much greater than the normal | examples=abnormal profits; abnormal ambition

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "abnormal" in the context of "patients whose blood counts are abnormal".
The context is medical, referring to blood counts that are not normal, typical, or regular.
Sense 1: not normal; not typical or usual or regular or conforming to a norm. Synonyms: unnatural. Examples: abnormal powers of concentration; abnormal amounts of rain.
Sense 2: departing from the normal in e.g. intelligence and development. Examples: they were heartbroken when they learned their child was abnormal; an abnormal personality.
Sense 3: much greater than the normal. Examples: abnormal profits; abnormal ambition.

In the context of blood counts, "abnormal" means not normal, not typical, or not conforming to a norm (could be high or low, not necessarily "much greater").
Therefore, Sense 1 is the best fit.
Let's double check.
"abnormal blood counts" -> not normal, not typical or usual or regular or conforming to a norm.
Sense 1 fits perfectly.
Sense 2 is about intelligence/development.
Sense 3 is about "much greater than the normal", but blood counts can be abnormally low as well.
So Sense 1 is the correct choice.
The output format must be exactly {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: have
Target surface form: have
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who <t>have</t> certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=have%2:40:00:: | definition=have or possess, either in a concrete or an abstract sense | synonyms=have got, hold | examples=She has $1,000 in the bank; He has got two beautiful daughters
2. sense_key=have%2:42:00:: | definition=have as a feature | synonyms=feature | examples=This restaurant features the most famous chefs in France
3. sense_key=have%2:39:06:: | definition=go through (mental or physical states or experiences) | synonyms=experience, receive, get | examples=get an idea; experience vertigo
4. sense_key=have%2:40:04:: | definition=have ownership or possession of | synonyms=own, possess | examples=He owns three houses in Florida; How many cars does she have?
5. sense_key=have%2:30:00:: | definition=cause to move; cause to be in a certain position or condition | synonyms=get, let | examples=He got his squad on the ball; This let me in for a big surprise
6. sense_key=have%2:34:00:: | definition=serve oneself to, or consume regularly | synonyms=consume, ingest, take in, take | examples=Have another bowl of chicken soup!; I don't take sugar in my coffee
7. sense_key=have%2:41:00:: | definition=have a personal or business relationship with someone | examples=have a postdoc; have an assistant
8. sense_key=have%2:36:00:: | definition=organize or be responsible for | synonyms=hold, throw, make, give | examples=hold a reception; have, throw, or make a party
9. sense_key=have%2:40:01:: | definition=have left | examples=I have two years left; I don't have any money left
10. sense_key=have%2:42:12:: | definition=be confronted with | examples=What do we have here?; Now we have a fine mess
11. sense_key=have%2:30:01:: | definition=undergo | synonyms=experience | examples=The stocks had a fast run-up
12. sense_key=have%2:29:02:: | definition=suffer from; be ill with | examples=She has arthritis
13. sense_key=have%2:32:00:: | definition=cause to do; cause to act in a specified manner | synonyms=induce, stimulate, cause, get, make | examples=The ads induced me to buy a VCR; My children finally got me to buy a computer
14. sense_key=have%2:40:05:: | definition=receive willingly something given or offered | synonyms=accept, take | examples=The only girl who would have him was the miller's daughter; I won't have this dog in my house!
15. sense_key=have%2:40:03:: | definition=get something; come into possession of | synonyms=receive | examples=receive payment; receive a gift
16. sense_key=have%2:29:05:: | definition=undergo (as of injuries and illnesses) | synonyms=suffer, sustain, get | examples=She suffered a fracture in the accident; He had an insulin shock after eating three candy bars
17. sense_key=have%2:40:02:: | definition=achieve a point or goal | synonyms=get, make | examples=Nicklaus had a 70; The Brazilian team got 4 goals
18. sense_key=have%2:29:00:: | definition=cause to be born | synonyms=give birth, deliver, bear, birth | examples=My wife had twins yesterday!
19. sense_key=have%2:35:00:: | definition=have sex with; archaic use | synonyms=take | examples=He had taken this woman when she was most vulnerable

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who <t>have</t> certain other side effects."
The target word is "have".
The phrase is "have certain other side effects".
This means to suffer from or be ill with, or to undergo (as of injuries and illnesses).
Let's check the candidate senses:
12. sense_key=have%2:29:02:: | definition=suffer from; be ill with | examples=She has arthritis
16. sense_key=have%2:29:05:: | definition=undergo (as of injuries and illnesses) | synonyms=suffer, sustain, get | examples=She suffered a fracture in the accident; He had an insulin shock after eating three candy bars

Wait, "have certain other side effects". Side effects are like illnesses or conditions.
Sense 12: suffer from; be ill with.
Sense 16: undergo (as of injuries and illnesses).
Let's look at the phrasing: "who have certain other side effects".
Is it "suffer from; be ill with" (12) or "undergo" (16)?
"have side effects" is very similar to "have arthritis" (12).
Let's check WordNet for "have side effects".
Actually, "have" + illness/symptom is usually sense 12 (suffer from; be ill with).
Let's see: "She has arthritis" -> sense 12.
"have certain other side effects" -> suffer from certain other side effects.
Let's consider sense 12 vs 16.
Sense 12: suffer from; be ill with.
Sense 16: undergo (as of injuries and illnesses).
"have side effects" is a state of suffering from them.
Let's check if there is a more specific sense.
"have" + "side effects" -> suffer from.
I will choose 12.
Wait, let's re-read 12: "suffer from; be ill with".
Let's re-read 16: "undergo (as of injuries and illnesses)".
"have side effects" is more like "suffer from" than "undergo". "Undergo" is more like "have an insulin shock" or "suffer a fracture".
I'll go with 12.
Let's double check.
"patients whose blood counts are abnormal or who have certain other side effects."
"have" = suffer from.
Yes, 12 is the best fit.
Another option: 1. have or possess, either in a concrete or an abstract sense. But 12 is more specific to medical conditions/side effects.
I will output 12.
Wait, let's look at 12 again. "suffer from; be ill with".
Is "side effects" an illness? Yes, in this context, it's a medical condition they suffer from.
I'll output 12.
Let's review 16: "undergo (as of injuries and illnesses)". "He had an insulin shock".
"have side effects" is a state, not an event like "undergo". So 12 is better.
I'll output 12.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: certain
Target surface form: certain
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have <t>certain</t> other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=certain%5:00:00:definite:00 | definition=definite but not specified or identified | examples=set aside a certain sum each week; to a certain degree
2. sense_key=certain%3:00:02:: | definition=having or feeling no doubt or uncertainty; confident and assured | synonyms=sure | examples=felt certain of success; was sure (or certain) she had seen it
3. sense_key=certain%3:00:01:: | definition=established beyond doubt or question; definitely known | examples=what is certain is that every effect must have a cause; it is certain that they were on the bus
4. sense_key=certain%3:00:03:: | definition=certain to occur; destined or inevitable; ; ; - Benjamin Franklin | synonyms=sure | examples=he was certain to fail; his fate is certain
5. sense_key=certain%3:00:05:: | definition=established irrevocably | synonyms=sealed | examples=his fate is sealed
6. sense_key=certain%5:00:00:reliable:00 | definition=reliable in operation or effect | synonyms=sure | examples=a quick and certain remedy; a sure way to distinguish the two
7. sense_key=certain%5:00:00:careful:00 | definition=exercising or taking care great enough to bring assurance | synonyms=sure | examples=be certain to disconnect the iron when you are through; be sure to lock the doors

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "certain" in the context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
Here, "certain" means "definite but not specified or identified".
Let's check the candidate senses:
1. sense_key=certain%5:00:00:definite:00 | definition=definite but not specified or identified | examples=set aside a certain sum each week; to a certain degree
2. sense_key=certain%3:00:02:: | definition=having or feeling no doubt or uncertainty; confident and assured
3. sense_key=certain%3:00:01:: | definition=established beyond doubt or question; definitely known
4. sense_key=certain%3:00:03:: | definition=certain to occur; destined or inevitable
5. sense_key=certain%3:00:05:: | definition=established irrevocably
6. sense_key=certain%5:00:00:reliable:00 | definition=reliable in operation or effect
7. sense_key=certain%5:00:00:careful:00 | definition=exercising or taking care great enough to bring assurance

In the context, "certain other side effects" means specific but unspecified side effects. This matches sense 1: "definite but not specified or identified".

Let's double check.
"certain other side effects" -> specific side effects, but not named here.
Sense 1: definite but not specified or identified.
Yes, sense 1 is the best fit.
Context: "who have certain other side effects."
Sense 1 fits perfectly.
Let's review the format: {"sense_index": 1}.
Done.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain <t>other</t> side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "other" in the context: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
The word "other" here means "not the same one or ones already mentioned or implied".
Let's check the candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Sense 1 fits perfectly: "certain other side effects" means side effects not already mentioned (like abnormal blood counts).
Therefore, the best indexed sense is 1.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: side_effect
Target surface form: side effects
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other <t>side effects</t>. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
2. sense_key=side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target lemma is "side_effect" and the surface form is "side effects".
Context: "To reduce side effects, patients should take a corticosteroid and folic acid... Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
This is clearly about the secondary and usually adverse effect of a drug or therapy.
Candidate sense 1: side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
Candidate sense 2: side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Sense 1 is the best fit because it specifically mentions "drug or therapy", which perfectly matches the context of Alimta (a drug/chemotherapy).

Therefore, the sense index is 1.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: use
Context:
The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for <t>use</t> in patients with moderate or severe kidney problems. For more information, see the Summary of Product Characteristics (also part of the EPAR).

Candidate senses:
1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "use" in the context: "Alimta is not recommended for <t>use</t> in patients with moderate or severe kidney problems."
The context is about the administration or application of a drug (Alimta) in patients.
Let's look at the candidate senses:
1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role
3. sense_key=use%1:07:02:: | definition=a particular service
4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing
5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior
6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence
7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property

Sense 1: "the act of using" - "the use of narcotic drugs" is very similar to "use in patients".
Let's check the context again: "Alimta is not recommended for use in patients with moderate or severe kidney problems."
This means the act of using the drug in these patients.
Sense 1 fits perfectly.
Let's double check.
"use of narcotic drugs" -> "use in patients"
Yes, sense 1 is the best fit.
Sense 1 index is 1.
End of thought.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in <t>patients</t> with moderate or severe kidney problems. For more information, see the Summary of Product Characteristics (also part of the EPAR).

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "patients" in the context of medical treatment ("The recommended dose of Alimta is 500 mg per square metre of body surface area... To reduce side effects, patients should take a corticosteroid...").
The context clearly refers to people who require medical care.
Candidate sense 1: "a person who requires medical care" (patient%1:18:00::)
Candidate sense 2: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" (patient%1:10:00::)

Sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: moderate
Target surface form: moderate
Context:
The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with <t>moderate</t> or severe kidney problems. For more information, see the Summary of Product Characteristics (also part of the EPAR).

Candidate senses:
1. sense_key=moderate%3:00:00:: | definition=being within reasonable or average limits; not excessive or extreme | examples=moderate prices; a moderate income
2. sense_key=moderate%5:00:00:mild:00 | definition=not extreme | synonyms=temperate | examples=a moderate penalty; temperate in his response to criticism
3. sense_key=moderate%5:00:00:temperate:00 | definition=marked by avoidance of extravagance or extremes | synonyms=restrained | examples=moderate in his demands; restrained in his response

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "moderate" in the context: "Alimta is not recommended for use in patients with moderate or severe kidney problems."
The senses are:
1. moderate%3:00:00:: (being within reasonable or average limits; not excessive or extreme)
2. moderate%5:00:00:mild:00 (not extreme)
3. moderate%5:00:00:temperate:00 (marked by avoidance of extravagance or extremes)

Wait, "moderate or severe kidney problems".
Sense 1: being within reasonable or average limits; not excessive or extreme.
Sense 2: not extreme.
Sense 3: marked by avoidance of extravagance or extremes.

Let's look at the part of speech. "moderate" is an adjective here.
Sense 1 is an adjective (3:00:00).
Sense 2 is an adjective (5:00:00).
Sense 3 is an adjective (5:00:00).

Wait, "moderate" in medical contexts usually means "not extreme" or "average".
Let's check the examples:
Sense 1: moderate prices; a moderate income.
Sense 2: a moderate penalty; temperate in his response to criticism.
Sense 3: moderate in his demands; restrained in his response.

"moderate or severe kidney problems" -> "moderate" here means "not extreme" or "average".
Is it sense 1 or sense 2?
Sense 1: being within reasonable or average limits; not excessive or extreme.
Sense 2: not extreme.

Let's look at WordNet.
moderate (adj)
1. moderate - being within reasonable or average limits; not excessive or extreme; "moderate prices"; "a moderate income"
2. moderate - not extreme; "a moderate penalty"; "temperate in his response to criticism"
3. moderate - marked by avoidance of extravagance or extremes; "moderate in his demands"; "restrained in his response"

In "moderate or severe kidney problems", it's a degree of severity. "moderate" means not extreme, but more than mild.
Wait, "moderate" as in "moderate or severe" is often sense 1 or 2.
Let's consider "moderate" meaning "not extreme" (sense 2).
Or "being within reasonable or average limits" (sense 1).
Actually, "moderate" in medical terms (mild, moderate, severe) usually aligns with "not extreme" or "average".
Let's check the synsets.
Sense 1: moderate (adj) - being within reasonable or average limits; not excessive or extreme.
Sense 2: moderate (adj) - not extreme.

Wait, if it's "moderate or severe", it's a scale.
Is there a better fit?
Let's search for "moderate" in WordNet.
Sense 1: moderate (adj) - being within reasonable or average limits; not excessive or extreme.
Sense 2: moderate (adj) - not extreme.

Let's look at the context: "moderate or severe kidney problems".
"moderate" here means "not extreme" (as opposed to severe, which is extreme).
Wait, "moderate" in "moderate or severe" is an adjective.
Let's choose sense 1 because "moderate" as a degree (mild, moderate, severe) is often mapped to "being within reasonable or average limits; not excessive or extreme" or "not extreme".
Actually, "moderate" meaning "not extreme" is sense 2.
Let's re-read the definitions.
1. being within reasonable or average limits; not excessive or extreme
2. not extreme
3. marked by avoidance of extravagance or extremes

"moderate kidney problems" -> not extreme kidney problems.
Wait, "moderate" in medical contexts is often sense 1.
Let's check if there is a specific WordNet sense for "moderate" as in "moderate pain" or "moderate disease".
In WordNet, "moderate" (adj) has:
1. moderate - being within reasonable or average limits; not excessive or extreme; "moderate prices"; "a moderate income"
2. moderate - not extreme; "a moderate penalty"; "temperate in his response to criticism"
3. moderate - marked by avoidance of extravagance or extremes; "moderate in his demands"; "restrained in his response"

"moderate or severe" -> "moderate" is the opposite of severe (extreme). So "not extreme" (sense 2) might be the best fit.
Wait, "moderate" in "moderate or severe" means it's in the middle. "being within reasonable or average limits" (sense 1) might be better because it implies a middle ground.
Let's consider "moderate" as "not extreme".
Actually, "moderate" in "moderate or severe" is often sense 1.
Let's look at similar examples. "moderate pain" -> sense 1 or 2?
"moderate" (adj) - being within reasonable or average limits; not excessive or extreme.
I will go with sense 1.
Wait, let's think if "moderate" in "moderate or severe" is sense 1.
"moderate" = average, not excessive.
Let's choose 1.
Wait, "moderate" in "moderate or severe" could be sense 1.
Let's check sense 1: "being within reasonable or average limits; not excessive or extreme".
Sense 2: "not extreme".
I'll output 1.
Let's reconsider. "moderate" in "moderate or severe" is a degree. "moderate" means "not extreme" but also "average".
I'll go with 1.
Wait, "moderate" in "moderate or severe" is often sense 1.
Let's choose 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: severe
Target surface form: severe
Context:
The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or <t>severe</t> kidney problems. For more information, see the Summary of Product Characteristics (also part of the EPAR).

Candidate senses:
1. sense_key=severe%5:00:00:intense:00 | definition=intensely or extremely bad or unpleasant in degree or quality | synonyms=terrible, wicked | examples=severe pain; a severe case of flu
2. sense_key=severe%5:00:00:strong:00 | definition=very strong or vigorous | synonyms=hard, knockout | examples=strong winds; a hard left to the chin
3. sense_key=severe%5:00:00:plain:01 | definition=severely simple | synonyms=austere, stark, stern | examples=a stark interior
4. sense_key=severe%5:00:02:nonindulgent:00 | definition=unsparing and uncompromising in discipline or judgment; - H.G.Wells | synonyms=spartan | examples=a parent severe to the pitch of hostility; a hefty six-footer with a rather severe mien
5. sense_key=severe%5:00:00:critical:03 | definition=causing fear or anxiety by threatening great harm | synonyms=dangerous, grave, grievous, serious, life-threatening | examples=a dangerous operation; a grave situation
6. sense_key=severe%5:00:01:bad:00 | definition=very bad in degree or extent | examples=a severe worldwide depression; the house suffered severe damage

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "severe" in the context: "Alimta is not recommended for use in patients with moderate or severe kidney problems."
The context is about medical conditions, specifically "kidney problems".
Let's evaluate the candidate senses:
1. intensely or extremely bad or unpleasant in degree or quality (severe pain, severe case of flu)
2. very strong or vigorous (strong winds)
3. severely simple (stark interior)
4. unsparing and uncompromising in discipline or judgment (severe mien)
5. causing fear or anxiety by threatening great harm (dangerous, grave, grievous, serious, life-threatening)
6. very bad in degree or extent (severe worldwide depression, severe damage)

Wait, "severe kidney problems" - is it sense 1 or sense 5 or sense 6?
Let's look at sense 1: "intensely or extremely bad or unpleasant in degree or quality" -> "severe case of flu". This matches "severe kidney problems" (a severe case of a medical condition).
Let's look at sense 5: "causing fear or anxiety by threatening great harm" -> "dangerous, grave, grievous, serious, life-threatening". "severe kidney problems" could be serious.
Let's look at sense 6: "very bad in degree or extent" -> "severe worldwide depression; the house suffered severe damage".

Wait, "severe" in medical contexts (like "severe kidney problems", "severe case of flu") is often sense 1.
Let's check the examples for sense 1: "severe pain; a severe case of flu". "severe kidney problems" is very similar to "a severe case of flu".
Let's check sense 5: "a dangerous operation; a grave situation".
Let's check sense 6: "a severe worldwide depression; the house suffered severe damage".

Is "severe kidney problems" more like "severe case of flu" (sense 1) or "severe damage" (sense 6)?
"severe" modifying a medical condition or disease is typically sense 1.
Let's re-read sense 1: "intensely or extremely bad or unpleasant in degree or quality".
Synonyms: terrible, wicked.
Examples: severe pain; a severe case of flu.

Wait, WordNet has:
severe (adj)
1. intensely or extremely bad or unpleasant in degree or quality; "severe pain"; "a severe case of flu"
2. very strong or vigorous; "strong winds"; "a hard left to the chin"; "a severe beating"
3. severely simple; "a stark interior"
4. unsparing and uncompromising in discipline or judgment; "a parent severe to the pitch of hostility"; "a hefty six-footer with a rather severe mien"; "a strict teacher"
5. causing fear or anxiety by threatening great harm; "a dangerous operation"; "a grave situation"; "a grave illness"; "grievous bodily harm"; "a serious wound"; "a serious turn of events"; "a severe case of pneumonia"; "a life-threatening disease"

Wait, "a severe case of pneumonia" is in sense 5!
Let's check the examples for sense 5: "a dangerous operation; a grave situation; a grave illness; grievous bodily harm; a serious wound; a serious turn of events; a severe case of pneumonia; a life-threatening disease".
Ah! "a severe case of pneumonia" is in sense 5.
Wait, let's look at the candidate senses provided in the prompt:
1. sense_key=severe%5:00:00:intense:00 | definition=intensely or extremely bad or unpleasant in degree or quality | synonyms=terrible, wicked | examples=severe pain; a severe case of flu
5. sense_key=severe%5:00:00:critical:03 | definition=causing fear or anxiety by threatening great harm | synonyms=dangerous, grave, grievous, serious, life-threatening | examples=a dangerous operation; a grave situation

Wait, the prompt says:
1. sense_key=severe%5:00:00:intense:00 | definition=intensely or extremely bad or unpleasant in degree or quality | synonyms=terrible, wicked | examples=severe pain; a severe case of flu
5. sense_key=severe%5:00:00:critical:03 | definition=causing fear or anxiety by threatening great harm | synonyms=dangerous, grave, grievous, serious, life-threatening | examples=a dangerous operation; a grave situation

Wait, in WordNet, "severe" has:
- severe (adj) 1: intensely or extremely bad or unpleasant in degree or quality ("severe pain"; "a severe case of flu")
- severe (adj) 5: causing fear or anxiety by threatening great harm ("a dangerous operation"; "a grave situation"; "a grave illness"; "grievous bodily harm"; "a serious wound"; "a serious turn of events"; "a severe case of pneumonia"; "a life-threatening disease")

Is "severe kidney problems" sense 1 or sense 5?
"moderate or severe kidney problems"
In medical terminology, "moderate or severe" is a standard grading of severity (degree or extent).
Sense 1: "intensely or extremely bad or unpleasant in degree or quality"
Sense 6: "very bad in degree or extent" ("a severe worldwide depression"; "the house suffered severe damage")

Let's look at sense 1 again. "severe case of flu". "severe kidney problems" is a medical condition.
But wait, "moderate or severe" implies a scale of degree.
Sense 1: "intensely or extremely bad or unpleasant in degree or quality"
Sense 6: "very bad in degree or extent"

Let's check WordNet 3.1 for "severe":
1. intensely or extremely bad or unpleasant in degree or quality; "severe pain"; "a severe case of flu"
2. very strong or vigorous; "strong winds"; "a hard left to the chin"; "a severe beating"
3. severely simple; "a stark interior"
4. unsparing and uncompromising in discipline or judgment; "a parent severe to the pitch of hostility"; "a hefty six-footer with a rather severe mien"; "a strict teacher"
5. causing fear or anxiety by threatening great harm; "a dangerous operation"; "a grave situation"; "a grave illness"; "grievous bodily harm"; "a serious wound"; "a serious turn of events"; "a severe case of pneumonia"; "a life-threatening disease"
6. very bad in degree or extent; "a severe worldwide depression"; "the house suffered severe damage"

Is "severe kidney problems" sense 1 or 5 or 6?
"moderate or severe kidney problems"
"severe" here means "very bad in degree or extent" or "intensely or extremely bad in degree or quality".
Actually, "severe" in "moderate or severe" is often mapped to sense 1 or 6.
Let's consider "severe case of flu" (sense 1). "severe kidney problems" is very similar to "severe case of flu".
Wait, sense 1 has "severe case of flu".
Sense 5 has "severe case of pneumonia".
What is the difference between "severe case of flu" and "severe case of pneumonia"?
In WordNet, "severe case of flu" is sense 1. "severe case of pneumonia" is sense 5.
Why? Because pneumonia is life-threatening (causing fear or anxiety by threatening great harm), whereas flu is just unpleasant/bad in degree.
Kidney problems can be life-threatening, but "moderate or severe kidney problems" is a standard medical classification of degree.
Let's look at sense 1: "intensely or extremely bad or unpleasant in degree or quality".
Let's look at sense 6: "very bad in degree or extent".
"moderate or severe" -> degree.
Is it sense 1 or 6?
"severe kidney problems" -> "severe" modifies "kidney problems".
"severe pain" (1), "severe case of flu" (1).
"severe worldwide depression" (6), "severe damage" (6).
"severe kidney problems" is a medical condition, like "severe case of flu". So sense 1 is highly likely.

Let's rethink: does "severe" in "moderate or severe" mean "very bad in degree or extent" (sense 6)?
"moderate or severe" is a scale of degree.
Sense 1: "intensely or extremely bad or unpleasant in degree or quality"
Sense 6: "very bad in degree or extent"
Actually, in many WSD datasets, "severe" in medical contexts like "severe pain", "severe case of flu", "severe kidney problems" is sense 1.
Let's check the synonyms for sense 1: terrible, wicked.
Synonyms for sense 6: none listed in the prompt, but maybe "bad".
Wait, the prompt says:
1. sense_key=severe%5:00:00:intense:00 | definition=intensely or extremely bad or unpleasant in degree or quality | synonyms=terrible, wicked | examples=severe pain; a severe case of flu
6. sense_key=severe%5:00:01:bad:00 | definition=very bad in degree or extent | examples=a severe worldwide depression; the house suffered severe damage

"severe kidney problems" -> is it "intensely or extremely bad or unpleasant in degree or quality" or "very bad in degree or extent"?
"severe" in "moderate or severe" is about the extent/degree of the problem.
But "severe case of flu" is also about the degree of the case.
Let's search for "severe kidney problems" in WordNet or similar datasets.
In SemEval or similar, "severe" modifying a disease/condition is often sense 1.
"severe pain" (1)
"severe case of flu" (1)
"severe kidney problems" is a condition.
Let's choose sense 1.

Wait, looking at the exact phrase "moderate or severe kidney problems", "severe" is the opposite of "moderate".
"moderate" means average in amount, intensity, quality, or degree.
"severe" means very great in degree.
Sense 1: "intensely or extremely bad or unpleasant in degree or quality"
Sense 6: "very bad in degree or extent"
Is there a difference?
"severe damage" (6)
"severe depression" (6)
"severe pain" (1)
"severe case of flu" (1)
"severe kidney problems" is closer to "severe case of flu" (a medical condition) than to "severe damage" or "severe depression" (though depression can be medical, worldwide depression is economic).
I will go with sense 1.

Let's double check sense 1 vs sense 5.
Sense 5: "causing fear or anxiety by threatening great harm" -> "a severe case of pneumonia".
Kidney problems can be serious, but "moderate or severe" is a standard grading. "Severe" here just means high degree, not necessarily "threatening great harm" in the specific sense of sense 5, although it could be. But "moderate or severe" pairs them as degrees.
I'll bet on sense 1.

Let's review the prompt's candidate 1:
1. sense_key=severe%5:00:00:intense:00 | definition=intensely or extremely bad or unpleasant in degree or quality | synonyms=terrible, wicked | examples=severe pain; a severe case of flu

Candidate 6:
6. sense_key=severe%5:00:01:bad:00 | definition=very bad in degree or extent | examples=a severe worldwide depression; the house suffered severe damage

"severe kidney problems" -> "severe" is an adjective describing the kidney problems.
"severe case of flu" is a very close match to "severe kidney problems". Both are medical conditions described by their severity.
Therefore, sense 1 is the best fit.
Another option: sense 1 is "intense", sense 6 is "bad". "severe" in medical terms is often "intense" or "extreme" in degree.
I will choose 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: problem
Target surface form: problems
Context:
The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney <t>problems</t>. For more information, see the Summary of Product Characteristics (also part of the EPAR).

Candidate senses:
1. sense_key=problem%1:26:00:: | definition=a state of difficulty that needs to be resolved | synonyms=job | examples=she and her husband are having problems; it is always a job to contact him
2. sense_key=problem%1:10:00:: | definition=a question raised for consideration or solution | examples=our homework consisted of ten problems to solve
3. sense_key=problem%1:09:00:: | definition=a source of difficulty | synonyms=trouble | examples=one trouble after another delayed the job; what's the problem?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "problems" in the context: "Alimta is not recommended for use in patients with moderate or severe kidney problems."
The context refers to medical conditions or difficulties related to the kidneys.
Let's evaluate the candidate senses:
1. sense_key=problem%1:26:00:: | definition=a state of difficulty that needs to be resolved | synonyms=job | examples=she and her husband are having problems; it is always a job to contact him
2. sense_key=problem%1:10:00:: | definition=a question raised for consideration or solution | examples=our homework consisted of ten problems to solve
3. sense_key=problem%1:09:00:: | definition=a source of difficulty | synonyms=trouble | examples=one trouble after another delayed the job; what's the problem?

Wait, "kidney problems" means a state of difficulty or a source of difficulty.
Let's look at sense 1: "a state of difficulty that needs to be resolved" (e.g., having problems).
Sense 3: "a source of difficulty" (e.g., one trouble after another).
Is "kidney problems" a state of difficulty or a source of difficulty?
Actually, in WordNet, "problem" as a medical condition or a state of difficulty is often sense 1.
Let's check the examples: "she and her husband are having problems" -> state of difficulty.
"one trouble after another delayed the job" -> source of difficulty.
"moderate or severe kidney problems" -> a state of difficulty (medical condition).
Wait, "kidney problems" is a state of difficulty that needs to be resolved (or managed).
Let's consider "problem" in WordNet:
1. problem (a state of difficulty that needs to be resolved) "she and her husband are having problems"; "it is always a job to contact him"
2. problem (a question raised for consideration or solution) "our homework consisted of ten problems to solve"
3. problem (a source of difficulty) "one trouble after another delayed the job"; "what's the problem?"

"Kidney problems" is a state of difficulty (a medical issue).
Let's see: "having problems" -> state of difficulty.
"moderate or severe kidney problems" -> state of difficulty.
I will choose sense 1.
Wait, let's re-read sense 1: "a state of difficulty that needs to be resolved".
Sense 3: "a source of difficulty".
Is a kidney problem a source of difficulty or a state of difficulty?
"patients with moderate or severe kidney problems" -> patients who have a state of difficulty (medical condition).
I'll go with 1.
Let's double check. "kidney problems" = medical problems. Medical problems are states of difficulty.
Yes, sense 1.
Let's review the examples for sense 1: "she and her husband are having problems".
"having kidney problems" fits perfectly with "having problems".
Therefore, sense 1 is the best fit.
Another option: sense 3 "a source of difficulty". "What's the problem?" "One trouble after another".
"Kidney problems" is a condition, a state of difficulty.
I will output 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: more
Target surface form: more
Context:
It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems. For <t>more</t> information, see the Summary of Product Characteristics (also part of the EPAR). How does Alimta work?

Candidate senses:
1. sense_key=more%3:00:01:: | definition=(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree | synonyms=more than | examples=more land; more support
2. sense_key=more%3:00:02:: | definition=(comparative of `many' used with count nouns) quantifier meaning greater in number | examples=a hall with more seats; we have no more bananas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "more" in the context: "For <t>more</t> information, see the Summary of Product Characteristics (also part of the EPAR)."
The phrase is "more information".
"Information" is a mass noun.
Sense 1: (comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree. Examples: more land; more support.
Sense 2: (comparative of `many' used with count nouns) quantifier meaning greater in number. Examples: a hall with more seats; we have no more bananas.

Since "information" is a mass noun, "more" here is the comparative of "much" used with mass nouns.
Therefore, Sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: information
Target surface form: information
Context:
It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems. For more <t>information</t>, see the Summary of Product Characteristics (also part of the EPAR). How does Alimta work?

Candidate senses:
1. sense_key=information%1:10:00:: | definition=a message received and understood | synonyms=info
2. sense_key=information%1:09:00:: | definition=knowledge acquired through study or experience or instruction
3. sense_key=information%1:10:02:: | definition=formal accusation of a crime
4. sense_key=information%1:14:00:: | definition=a collection of facts from which conclusions may be drawn | synonyms=data | examples=statistical data
5. sense_key=information%1:07:00:: | definition=(communication theory) a numerical measure of the uncertainty of an outcome | synonyms=selective information, entropy | examples=the signal contained thousands of bits of information

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "information" in the context: "For more information, see the Summary of Product Characteristics (also part of the EPAR)."
The context is about medical instructions, specifically referring to a document (Summary of Product Characteristics) that contains facts, details, or data about the drug Alimta.
Let's evaluate the candidate senses:
1. a message received and understood (info)
2. knowledge acquired through study or experience or instruction
3. formal accusation of a crime
4. a collection of facts from which conclusions may be drawn (data)
5. (communication theory) a numerical measure of the uncertainty of an outcome

"For more information" in this context refers to a collection of facts or details about the product, which aligns with sense 4: "a collection of facts from which conclusions may be drawn" (synonyms: data).
Wait, "knowledge acquired through study or experience or instruction" (sense 2) or "a collection of facts from which conclusions may be drawn" (sense 4).
Let's look at similar contexts. "For more information, see..." usually refers to data or facts provided in a document.
Sense 4: "a collection of facts from which conclusions may be drawn" (data).
Let's check sense 1: "a message received and understood".
Sense 2: "knowledge acquired through study or experience or instruction".
Sense 4 is often used for "information" in the sense of data, facts, details provided in a document. "For more information" -> "For more data/facts".
Let's consider "information" as "a collection of facts from which conclusions may be drawn".
Is it sense 4? Yes, "data" is a good synonym here. "For more data, see the Summary..."
Let's double check sense 4.
Definition: a collection of facts from which conclusions may be drawn.
Synonyms: data.
Examples: statistical data.
In "For more information, see the Summary of Product Characteristics", it means "For more facts/details/data".
I will choose sense 4.
Wait, let's consider sense 1: "a message received and understood". No.
Sense 2: "knowledge acquired through study or experience or instruction". No, it's not about personal knowledge.
Sense 4 fits best.
Let's review the prompt: "Return only a JSON object exactly like {"sense_index": 3}."
So {"sense_index": 4}.
Let's confirm.
"For more information, see the Summary of Product Characteristics"
Information here means facts, details, data.
Sense 4: a collection of facts from which conclusions may be drawn.
Yes.
End of thought.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: see
Target surface form: see
Context:
It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems. For more information, <t>see</t> the Summary of Product Characteristics (also part of the EPAR). How does Alimta work?

Candidate senses:
1. sense_key=see%2:39:00:: | definition=perceive by sight or have the power to perceive by sight | examples=You have to be a good observer to see all the details; Can you see the bird in that tree?
2. sense_key=see%2:31:01:: | definition=perceive (an idea or situation) mentally | synonyms=understand, realize, realise | examples=Now I see!; I just can't see your point
3. sense_key=see%2:39:02:: | definition=perceive or be contemporaneous with | synonyms=witness, find | examples=We found Republicans winning the offices; You'll see a lot of cheating in this school
4. sense_key=see%2:36:00:: | definition=imagine; conceive of; see in one's mind | synonyms=visualize, visualise, envision, project, fancy, figure | examples=I can't see him on horseback!; I can see what will happen
5. sense_key=see%2:31:00:: | definition=deem to be | synonyms=consider, reckon, view, regard | examples=She views this quite differently from me; I consider her to be shallow
6. sense_key=see%2:31:02:: | definition=get to know or become aware of, usually accidentally | synonyms=learn, hear, get word, get wind, pick up, find out | examples=I learned that she has two grown-up children; I see that you have been promoted
7. sense_key=see%2:39:03:: | definition=see or watch | synonyms=watch, view, catch, take in | examples=view a show on television; This program will be seen all over the world
8. sense_key=see%2:38:00:: | definition=come together | synonyms=meet, run into, encounter, run across, come across | examples=I'll probably see you at the meeting; How nice to see you again!
9. sense_key=see%2:32:00:: | definition=find out, learn, or determine with certainty, usually by making an inquiry or other effort | synonyms=determine, check, find out, ascertain, watch, learn | examples=I want to see whether she speaks French; See whether it works
10. sense_key=see%2:31:03:: | definition=be careful or certain to do something; make certain of something | synonyms=check, insure, see to it, ensure, control, ascertain | examples=He verified that the valves were closed; See that the curtains are closed
11. sense_key=see%2:41:11:: | definition=go to see for professional or business reasons | examples=You should see a lawyer; We had to see a psychiatrist
12. sense_key=see%2:41:12:: | definition=go to see for a social visit | examples=I went to see my friend Mary the other day
13. sense_key=see%2:41:10:: | definition=go to see a place, as for entertainment | synonyms=visit | examples=We went to see the Eiffel Tower in the morning
14. sense_key=see%2:41:14:: | definition=take charge of or deal with | synonyms=attend, take care, look | examples=Could you see about lunch?; I must attend to this matter
15. sense_key=see%2:35:09:: | definition=receive as a specified guest | examples=the doctor will see you now; The minister doesn't see anybody before noon
16. sense_key=see%2:41:00:: | definition=date regularly; have a steady relationship with | synonyms=go steady, go out, date | examples=Did you know that she is seeing an older man?; He is dating his former wife again!
17. sense_key=see%2:39:05:: | definition=see and understand, have a good eye | examples=The artist must first learn to see
18. sense_key=see%2:31:08:: | definition=deliberate or decide | examples=See whether you can come tomorrow; let's see--which movie should we see tonight?
19. sense_key=see%2:39:11:: | definition=observe as if with an eye | examples=The camera saw the burglary and recorded it
20. sense_key=see%2:39:13:: | definition=observe, check out, and look over carefully or inspect | synonyms=examine | examples=The customs agent examined the baggage; I must see your passport before you can enter the country
21. sense_key=see%2:39:12:: | definition=go or live through | synonyms=experience, go through | examples=We had many trials to go through; he saw action in Viet Nam
22. sense_key=see%2:38:03:: | definition=accompany or escort | synonyms=escort | examples=I'll see you to the door
23. sense_key=see%2:33:00:: | definition=match or meet | examples=I saw the bet of one of my fellow players
24. sense_key=see%2:31:13:: | definition=make sense of; assign a meaning to | synonyms=interpret, construe | examples=What message do you see in this letter?; How do you interpret his behavior?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "For more information, <t>see</t> the Summary of Product Characteristics (also part of the EPAR)."
The word "see" here means to consult, look at, or refer to a document for information.
Let's check the candidate senses.
1. perceive by sight
2. perceive mentally
3. perceive or be contemporaneous with
4. imagine
5. deem to be
6. get to know
7. see or watch
8. come together
9. find out, learn, or determine with certainty, usually by making an inquiry or other effort (synonyms: determine, check, find out, ascertain, watch, learn) - "I want to see whether she speaks French; See whether it works"
10. be careful or certain to do something
11. go to see for professional reasons
12. go to see for a social visit
13. go to see a place
14. take charge of or deal with
15. receive as a specified guest
16. date regularly
17. see and understand
18. deliberate or decide
19. observe as if with an eye
20. observe, check out, and look over carefully or inspect (synonyms: examine) - "I must see your passport before you can enter the country"
Wait, "see" in "see the Summary of Product Characteristics" means to look at, consult, or examine.
Let's re-read sense 20: "observe, check out, and look over carefully or inspect" synonyms: examine. Examples: "The customs agent examined the baggage; I must see your passport before you can enter the country".
Is there a better sense?
What about sense 9: "find out, learn, or determine with certainty, usually by making an inquiry or other effort" synonyms: determine, check, find out, ascertain, watch, learn. Examples: "I want to see whether she speaks French; See whether it works".
Wait, "see the Summary of Product Characteristics" means to look at or consult.
Let's check sense 20: "observe, check out, and look over carefully or inspect".
Is there a sense for "consult"?
Let's look at sense 20 again. "observe, check out, and look over carefully or inspect".
What about sense 1? "perceive by sight or have the power to perceive by sight".
What about sense 7? "see or watch" (view a show).
What about sense 20? "observe, check out, and look over carefully or inspect".
Let's consider "see" as in "see the manual". This is often mapped to "examine" or "look at".
Wait, sense 20: "observe, check out, and look over carefully or inspect" synonyms: examine.
Let's check sense 20. "I must see your passport before you can enter the country."
Is there another sense?
"see" meaning "consult" or "refer to".
Let's look at the options.
1. perceive by sight
2. perceive mentally
3. perceive or be contemporaneous with
4. imagine
5. deem to be
6. get to know
7. see or watch
8. come together
9. find out, learn, or determine with certainty
10. be careful or certain
11. go to see for professional
12. go to see for social
13. go to see a place
14. take charge of
15. receive as a specified guest
16. date regularly
17. see and understand
18. deliberate or decide
19. observe as if with an eye
20. observe, check out, and look over carefully or inspect
21. go or live through
22. accompany or escort
23. match or meet
24. make sense of

"see the Summary of Product Characteristics" -> look at, consult, examine.
Sense 20: "observe, check out, and look over carefully or inspect" (examine).
Is there any other sense?
Maybe sense 9: "find out, learn, or determine with certainty, usually by making an inquiry or other effort" (check, find out). "See whether it works".
But "see the Summary" is a direct object, not a clause. "See the Summary" = "Examine the Summary" or "Look at the Summary".
Sense 20 fits "examine" or "look over".
Let's check if there is a "consult" sense. No.
Let's check sense 20: "observe, check out, and look over carefully or inspect".
Could it be sense 1? "perceive by sight". "see the Summary" -> read/look at.
In WordNet, "see" as in "see the manual" is often sense 20 (examine) or sense 1 (perceive by sight).
Wait, "see" in "see the Summary of Product Characteristics" means to refer to it, to look at it.
Let's look at sense 20: "observe, check out, and look over carefully or inspect". Synonyms: examine.
Let's look at sense 1: "perceive by sight or have the power to perceive by sight".
Let's look at sense 7: "see or watch".
Let's look at sense 20 again. "I must see your passport before you can enter the country." This is "examine".
"see the Summary of Product Characteristics" -> examine the summary.
Is there a better fit?
What about sense 9? "find out, learn, or determine with certainty, usually by making an inquiry or other effort".
"see the Summary" -> to find out more information. "For more information, see the Summary..."
This is a very common phrase: "For more information, see [document]".
Does "see" here mean "examine" (20) or "find out" (9)?
Actually, "see" in "see page 5" or "see the manual" is often mapped to "examine" or "look at".
Let's check WordNet for "see" + document.
"see" (examine) - "I must see your passport".
"see" (perceive by sight) - "see the bird".
"see" (find out) - "see whether it works".
I think sense 20 is the best fit for "see the Summary of Product Characteristics" because it means to look at or examine the document.
Wait, let's consider sense 20: "observe, check out, and look over carefully or inspect".
Is there a sense for "consult"? No.
Let's consider sense 20.
Let's consider sense 1. "perceive by sight".
Let's consider sense 20. "observe, check out, and look over carefully or inspect".
Let's consider sense 9. "find out, learn, or determine with certainty, usually by making an inquiry or other effort".
"For more information, see the Summary..." -> "For more information, examine the Summary..." or "For more information, look at the Summary...".
I will go with sense 20.
Wait, let's look at sense 20 again. "observe, check out, and look over carefully or inspect".
Is "see the Summary" really "inspect"?
Maybe sense 1? "perceive by sight".
Let's search my internal knowledge for "For more information, see".
In many WSD datasets, "see" in "see the manual" or "see page X" is often sense 20 (examine) or sense 1 (perceive by sight).
Let's look at the synonyms for sense 20: examine.
Can you "examine" the Summary of Product Characteristics? Yes.
What about sense 9? "check, find out". "For more information, check the Summary..."
"check" is a synonym for sense 9.
"find out" is a synonym for sense 9.
"For more information, find out the Summary..." - no.
"For more information, check the Summary..." - yes.
But "see" is the verb. "see the Summary".
Let's look at sense 20: "observe, check out, and look over carefully or inspect".
"check out" is a synonym for sense 20.
"look over" is a synonym for sense 20.
"see the Summary" = "look over the Summary".
I think sense 20 is the most appropriate.
Let's double check sense 20.
"observe, check out, and look over carefully or inspect"
Examples: "The customs agent examined the baggage; I must see your passport before you can enter the country"
Yes, "see your passport" is very similar to "see the Summary". You are being directed to look at it.
I will choose sense 20.
Wait, let's consider sense 1. "perceive by sight". "see the Summary" -> read it. Reading is perceiving by sight. But "see" here is more active, like "consult".
Sense 20 is "examine".
Let's consider sense 20.
I'll output 20.
Let me reconsider sense 20 vs sense 1.
If I say "see the attached file", it means "look at" or "examine".
Sense 20: "observe, check out, and look over carefully or inspect".
I am confident in 20.
Let's review the options.
1. perceive by sight
20. observe, check out, and look over carefully or inspect
I will go with 20.
Wait, could it be 9? "find out, learn, or determine with certainty, usually by making an inquiry or other effort". Synonyms: determine, check, find out, ascertain, watch, learn.
"For more information, see the Summary..." -> "For more information, check the Summary..."
But "see" takes a direct object "the Summary". Sense 9 usually takes a clause: "see whether it works", "see if she speaks French".
Sense 20 takes a direct object: "see your passport", "examine the baggage".
So sense 20 is syntactically and semantically a better fit.
I will choose 20.