[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes."
The target word is "given" (lemma: give).
The context is about administering a medicine (Alimta) to a patient.
Let's look at the candidate senses.
Sense 19: give%2:40:19:: definition=give (as medicine) | examples=I gave him the drug
This perfectly matches the context of giving a medicine (Alimta) as an intravenous infusion.
Let's double check.
"It is given once every three weeks as an intravenous infusion lasting 10 minutes."
Sense 19: give (as medicine).
Yes, this is the exact sense.
Let's review the options.
19. sense_key=give%2:40:19:: | definition=give (as medicine) | examples=I gave him the drug
This is a perfect match.
I will return {"sense_index": 19}.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: once
Target surface form: once
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given <t>once</t> every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=once%4:02:00:: | definition=on one occasion | synonyms=one time, in one case | examples=once I ran into her
2. sense_key=once%4:02:02:: | definition=as soon as | examples=once we are home, we can rest
3. sense_key=once%4:02:01:: | definition=at a previous time | synonyms=formerly, at one time, erstwhile, erst | examples=at one time he loved her; her erstwhile writing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
The target word is "once" in the context: "It is given once every three weeks as an intravenous infusion lasting 10 minutes."
The context means "one time" every three weeks.
Let's look at the candidate senses:
1. sense_key=once%4:02:00:: | definition=on one occasion | synonyms=one time, in one case | examples=once I ran into her
2. sense_key=once%4:02:02:: | definition=as soon as | examples=once we are home, we can rest
3. sense_key=once%4:02:01:: | definition=at a previous time | synonyms=formerly, at one time, erstwhile, erst | examples=at one time he loved her; her erstwhile writing

"once every three weeks" means "one time" every three weeks.
Sense 1: "on one occasion", "one time". This fits perfectly.
Sense 2: "as soon as". Doesn't fit.
Sense 3: "at a previous time". Doesn't fit.

Therefore, the best sense is 1.
I will return {"sense_index": 1}.

format: unknown

native_finish_reason: stop

provider: Alibaba

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: every
Target surface form: every
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once <t>every</t> three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=every%5:00:00:all:00 | definition=(used of count nouns) each and all of the members of a group considered singly and without exception | examples=every person is mortal; every party is welcome
2. sense_key=every%5:00:02:all:00 | definition=each and all of a series of entities or intervals as specified | examples=every third seat; every two hours

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "every" in the context: "It is given once every three weeks as an intravenous infusion lasting 10 minutes."
The candidate senses are:
1. every%5:00:00:all:00: (used of count nouns) each and all of the members of a group considered singly and without exception (e.g., every person is mortal)
2. every%5:00:02:all:00: each and all of a series of entities or intervals as specified (e.g., every third seat; every two hours)

In the context, "every three weeks" refers to a series of intervals as specified.
This perfectly matches sense 2.
Therefore, the best indexed sense is 2.
I will return {"sense_index": 2}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: week
Target surface form: weeks
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three <t>weeks</t> as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=week%1:28:00:: | definition=any period of seven consecutive days | synonyms=hebdomad | examples=it rained for a week
2. sense_key=week%1:28:01:: | definition=hours or days of work in a calendar week | synonyms=workweek | examples=they worked a 40-hour week
3. sense_key=week%1:28:02:: | definition=a period of seven consecutive days starting on Sunday | synonyms=calendar week

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "weeks" in the context: "It is given once every three weeks as an intravenous infusion lasting 10 minutes."
The context refers to a period of seven consecutive days (a duration of time).
Sense 1: any period of seven consecutive days. Examples: "it rained for a week".
Sense 2: hours or days of work in a calendar week.
Sense 3: a period of seven consecutive days starting on Sunday.

The context "once every three weeks" refers to a duration of time, not specifically a calendar week starting on Sunday, nor a workweek.
Therefore, Sense 1 is the best fit.
Let's double check.
"once every three weeks" -> duration of 3 * 7 days.
Sense 1: any period of seven consecutive days.
Sense 3: a period of seven consecutive days starting on Sunday.
Sense 1 is the most appropriate for a duration.
I will output {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous <t>infusion</t> lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
2. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)
3. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)
4. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "infusion".
Context: "It is given once every three weeks as an intravenous <t>infusion</t> lasting 10 minutes."
This refers to the medical procedure of introducing a substance (a drug) into a vein.
Candidate senses:
1. solution obtained by steeping
2. process of extracting active properties by steeping
3. (medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues
4. the act of infusing or introducing a certain modifying element or quality

Sense 3 perfectly matches "intravenous infusion".
Therefore, the best indexed sense is 3.
I will return {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: last
Target surface form: lasting
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion <t>lasting</t> 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=last%2:42:00:: | definition=persist for a specified period of time | synonyms=endure | examples=The bad weather lasted for three days
2. sense_key=last%2:42:01:: | definition=continue to live through hardship or adversity | synonyms=survive, live, live on, go, endure, hold up | examples=We went without water and food for 3 days; These superstitions survive in the backwaters of America

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "lasting" (lemma: last).
Context: "It is given once every three weeks as an intravenous infusion lasting 10 minutes."
Sense 1: persist for a specified period of time (endure). Example: The bad weather lasted for three days.
Sense 2: continue to live through hardship or adversity (survive, live, live on, go, endure, hold up). Example: We went without water and food for 3 days.

In the context, "lasting 10 minutes" means persisting for a specified period of time.
Therefore, Sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: minute
Target surface form: minutes
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 <t>minutes</t>. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=minute%1:28:00:: | definition=a unit of time equal to 60 seconds or 1/60th of an hour | synonyms=min | examples=he ran a 4 minute mile
2. sense_key=minute%1:28:01:: | definition=an indefinitely short time | synonyms=moment, mo, second, bit | examples=wait just a moment; in a mo
3. sense_key=minute%1:28:02:: | definition=a particular point in time | synonyms=moment, second, instant | examples=the moment he arrived the party began
4. sense_key=minute%1:23:00:: | definition=a unit of angular distance equal to a 60th of a degree | synonyms=arcminute, minute of arc
5. sense_key=minute%1:10:00:: | definition=a short note | examples=the secretary keeps the minutes of the meeting
6. sense_key=minute%1:07:00:: | definition=distance measured by the time taken to cover it | synonyms=hour | examples=we live an hour from the airport; its just 10 minutes away

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "minutes" in the context: "It is given once every three weeks as an intravenous infusion lasting 10 <t>minutes</t>."
The context clearly refers to a unit of time equal to 60 seconds.
Candidate sense 1: "a unit of time equal to 60 seconds or 1/60th of an hour"
Candidate sense 2: "an indefinitely short time"
Candidate sense 3: "a particular point in time"
Candidate sense 4: "a unit of angular distance equal to a 60th of a degree"
Candidate sense 5: "a short note"
Candidate sense 6: "distance measured by the time taken to cover it"

Sense 1 is the best fit.
Index: 1.
JSON output: {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduce
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question
3. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
4. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
5. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
6. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
7. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
8. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
9. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
10. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
11. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
12. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
13. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
14. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
15. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
16. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
17. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
18. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
19. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
20. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "To reduce side effects, patients should take a corticosteroid and folic acid..."
The target word is "reduce".
The meaning is to cut down on, make a reduction in (the side effects).
Let's check the candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
This perfectly matches "reduce side effects" (cut down on side effects).

Let's check other senses:
8. lessen and make more modest (reduce one's standard of living)
19. lessen the strength or flavor of a solution or mixture (dilute)
1. is the best fit. "cut down on; make a reduction in".

Let's double check.
"To reduce side effects" -> to cut down on side effects.
Sense 1: cut down on; make a reduction in.
Yes, sense 1 is the most appropriate.
Context: "To reduce side effects, patients should take a corticosteroid and folic acid..."
Sense 1 fits perfectly.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: side_effect
Target surface form: side effects
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce <t>side effects</t>, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
2. sense_key=side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target lemma is "side_effect" and the surface form is "side effects".
Context: "To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta."
The context is about a medicine (Alimta) and its adverse effects.
Candidate sense 1: a secondary and usually adverse effect of a drug or therapy. Examples: severe headaches are one of the side effects of the drug.
Candidate sense 2: any adverse and unwanted secondary effect. Synonyms: fallout. Examples: a strategy to contain the fallout from the accounting scandal.

The context explicitly mentions "medicine", "treatment with Alimta", "corticosteroid", "vitamin B12", "anti-emetic medicine". This perfectly matches sense 1: "a secondary and usually adverse effect of a drug or therapy".

Therefore, the best indexed sense is 1.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, <t>patients</t> should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "patients" in the context of medical treatment ("The medicine can only be obtained with a prescription... To reduce side effects, patients should take a corticosteroid...").
The candidate senses are:
1. a person who requires medical care
2. the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause

The context clearly refers to people receiving medical care (taking corticosteroids, folic acid, receiving injections, etc.).
Therefore, sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "type" in the context: "folic acid (a <t>type</t> of vitamin)".
The context is talking about a subdivision or kind of vitamin.
Let's look at the candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group...
4. sense_key=type%1:10:01:: | definition=printed characters
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol
6. sense_key=type%1:06:00:: | definition=a small metal block...

Sense 1 fits perfectly: "a subdivision of a particular kind of thing" -> "a type of vitamin".
I will output {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: injection
Target surface form: injections
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=injection%1:04:00:: | definition=the forceful insertion of a substance under pressure
2. sense_key=injection%1:27:00:: | definition=any solution that is injected (as into the skin) | synonyms=injectant
3. sense_key=injection%1:04:01:: | definition=the act of putting a liquid into the body by means of a syringe | synonyms=shot | examples=the nurse gave him a flu shot

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "injections" in the context: "receive injections of vitamin B12 during treatment with Alimta."
The context talks about receiving injections of vitamin B12.
Candidate senses:
1. injection%1:04:00:: - the forceful insertion of a substance under pressure
2. injection%1:27:00:: - any solution that is injected (as into the skin) | synonyms=injectant
3. injection%1:04:01:: - the act of putting a liquid into the body by means of a syringe | synonyms=shot | examples=the nurse gave him a flu shot

In the context, "receive injections of vitamin B12" refers to the act of putting a liquid into the body by means of a syringe (or the shot itself, but "receive injections" usually refers to the act or the shot). Wait, "receive injections" could be the act of putting a liquid into the body. Let's look at sense 3: "the act of putting a liquid into the body by means of a syringe".
Sense 2: "any solution that is injected". "receive injections of vitamin B12" -> receive the solution? Or receive the act? "receive injections" is like "receive shots".
Let's check the examples for sense 3: "the nurse gave him a flu shot". "receive injections" aligns with "receive shots".
Wait, sense 3 is "the act of putting a liquid into the body by means of a syringe".
Sense 2 is "any solution that is injected".
Is "injections" here the act or the solution? "receive injections of vitamin B12". You receive the shot (the act or the instance).
Let's consider "receive injections". "receive shots".
Sense 3: "the act of putting a liquid into the body by means of a syringe".
Let's choose 3.
Wait, let's re-read carefully: "receive injections of vitamin B12".
If it's the act, it's sense 3.
Let's check WordNet for "injection".
Sense 1: the forceful insertion of a substance under pressure.
Sense 2: any solution that is injected (as into the skin).
Sense 3: the act of putting a liquid into the body by means of a syringe.
"receive injections" -> receive the act of putting a liquid into the body. "receive a shot".
I will go with 3.
Let's double check if 3 is better than 2. "receive injections of vitamin B12" -> receive the shot. Yes, 3 is the most common sense for "receive an injection".
"the nurse gave him a flu shot" -> "receive injections".
I'll output 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during <t>treatment</t> with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "treatment" in the context of medical care: "receive injections of vitamin B12 during treatment with Alimta."
The context is about medical procedures, medicine, anticancer chemotherapy, dose, side effects, etc.
Sense 1: care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention.
Sense 2: the management of someone or something.
Sense 3: a manner of dealing with something artistically.
Sense 4: an extended communication dealing with some particular topic.

Sense 1 is clearly the best fit for medical treatment.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is <t>given</t> with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is about a drug, Alimta, being administered to patients.
"Alimta should only be given under the supervision of a doctor..."
"It is given once every three weeks as an intravenous infusion..."
"When Alimta is given with cisplatin..."
The target word is "given".
Sense 19: give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
This perfectly matches the context of administering a drug/medicine.
Let's double check.
Sense 19: "give (as medicine)"
Context: "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
Yes, this is exactly giving as medicine.
Sense 19 is the best fit.
Let's review the options.
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
This is a perfect match.
I will return {"sense_index": 19}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic <t>medicine</t> (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "medicine" in the context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The context refers to an "anti-emetic medicine", which is a substance used to treat or prevent symptoms of disease (vomiting).
Sense 1: branches of medical science (nonsurgical techniques)
Sense 2: something that treats or prevents or alleviates the symptoms of disease (medication, medicament, medicinal drug)
Sense 3: the learned profession
Sense 4: punishment

Sense 2 is the best fit.
Index: 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to <t>prevent</t> vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "prevent" in the context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The phrase is "to prevent vomiting".
Sense 1: keep from happening or arising; make impossible (forestall, foreclose, preclude, forbid).
Sense 2: stop (someone or something) from doing something or being in a certain state (keep).

"prevent vomiting" means to keep vomiting from happening or arising.
Let's look at the synonyms: forestall, preclude.
Is it sense 1 or sense 2?
Sense 1: keep from happening or arising; make impossible. (e.g., preclude involvement)
Sense 2: stop (someone or something) from doing something or being in a certain state. (e.g., prevent the cancer from spreading, kept me from falling asleep).

Wait, "prevent vomiting" - vomiting is an event or state.
Let's check the examples.
Sense 1: keep from happening or arising; make impossible.
Sense 2: stop (someone or something) from doing something or being in a certain state.

"prevent vomiting" -> keep vomiting from happening.
Is vomiting "someone or something doing something"? No, it's an event.
"keep from happening or arising" fits "prevent vomiting" better.
Let's re-read Sense 1: "keep from happening or arising; make impossible"
Sense 2: "stop (someone or something) from doing something or being in a certain state"

Vomiting is an event, so "keep from happening" (Sense 1) is a better fit than "stop someone from doing something" (Sense 2).
Wait, "prevent dehydration" - dehydration is a state.
But "prevent vomiting" is the target.
Let's consider "prevent" in WordNet.
prevent%2:41:01:: keep from happening or arising; make impossible
prevent%2:41:00:: stop (someone or something) from doing something or being in a certain state

Actually, "prevent" + noun (vomiting, dehydration) usually maps to "keep from happening or arising".
Let's check the examples for Sense 1: "My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project"
Examples for Sense 2: "We must prevent the cancer from spreading; His snoring kept me from falling asleep"

Wait, "prevent vomiting" -> keep vomiting from happening.
Is it sense 1? Yes, "keep from happening or arising".
Let's double check.
"prevent" + gerund/noun (vomiting) -> keep from happening.
I will choose sense 1.
Wait, let's look at the synonyms for sense 1: forestall, foreclose, preclude, forbid.
Synonyms for sense 2: keep.
"prevent vomiting" -> keep vomiting from happening.
Actually, if I look at "prevent" in WordNet:
prevent v
1. keep from happening or arising; make impossible; "My sense of tact forbids an honest answer"; "Your role in the projects precludes your involvement in the competitive project"
2. stop (someone or something) from doing something or being in a certain state; "We must prevent the cancer from spreading"; "His snoring kept me from falling asleep"

"prevent vomiting" -> keep from happening.
I'll go with 1.
Let's reconsider. "prevent vomiting" is to keep it from happening.
Yes, 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: fluid
Target surface form: fluids
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and <t>fluids</t> (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=fluid%1:27:02:: | definition=a substance that is fluid at room temperature and pressure
2. sense_key=fluid%1:27:00:: | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "fluids" in the context of medical treatment: "an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The context talks about giving fluids to prevent dehydration.
Sense 1: a substance that is fluid at room temperature and pressure.
Sense 2: continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas.

Wait, looking at WordNet:
fluid%1:27:02:: "a substance that is fluid at room temperature and pressure" (e.g., bodily fluids, intravenous fluids).
fluid%1:27:00:: "continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas"

In medical contexts, "fluids" usually refers to bodily fluids or intravenous fluids, which are substances that are fluid at room temperature and pressure.
Let's check the examples for fluid%1:27:02::.
"bodily fluids"
"intravenous fluids"
Yes, "fluids" in the context of preventing dehydration refers to intravenous fluids or drinking fluids, which are substances that are fluid at room temperature and pressure.
Sense 1 is "a substance that is fluid at room temperature and pressure".
Sense 2 is "continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas".

Let's look at the distinction.
Sense 1: fluid%1:27:02:: (substance that is fluid at room temperature and pressure)
Sense 2: fluid%1:27:00:: (continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas)

In WordNet, "fluid" as a noun:
1. continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas
2. a substance that is fluid at room temperature and pressure

Wait, "fluids" to prevent dehydration. This is a substance (like saline solution) that is fluid at room temperature and pressure.
Let's consider "fluids" in WordNet.
Is it sense 1 or sense 2?
Sense 1 in the prompt is: sense_key=fluid%1:27:02:: | definition=a substance that is fluid at room temperature and pressure
Sense 2 in the prompt is: sense_key=fluid%1:27:00:: | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

Actually, "fluids" (plural) often maps to "a substance that is fluid at room temperature and pressure" (e.g., bodily fluids, intravenous fluids).
Let's check WordNet for "fluids".
"fluid" noun:
1. continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas
2. a substance that is fluid at room temperature and pressure

In medical contexts, "fluids" (like IV fluids) is sense 2 in WordNet (which is sense 1 in the prompt's list, wait: prompt says:
1. sense_key=fluid%1:27:02:: | definition=a substance that is fluid at room temperature and pressure
2. sense_key=fluid%1:27:00:: | definition=continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas

Yes, sense 1 in the prompt is fluid%1:27:02::.
Let's choose 1.
Wait, let's think if "fluids" to prevent dehydration is "a substance that is fluid at room temperature and pressure". Yes, IV fluids.
I will output 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prevent
Target surface form: prevent
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to <t>prevent</t> dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=prevent%2:41:01:: | definition=keep from happening or arising; make impossible | synonyms=forestall, foreclose, preclude, forbid | examples=My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project
2. sense_key=prevent%2:41:00:: | definition=stop (someone or something) from doing something or being in a certain state | synonyms=keep | examples=We must prevent the cancer from spreading; His snoring kept me from falling asleep

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "prevent" in the context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The context is about keeping something (vomiting, dehydration) from happening or arising.
Sense 1: keep from happening or arising; make impossible. Synonyms: forestall, foreclose, preclude, forbid.
Sense 2: stop (someone or something) from doing something or being in a certain state. Synonyms: keep. Examples: We must prevent the cancer from spreading; His snoring kept me from falling asleep.

In the context, "prevent vomiting" and "prevent dehydration" means keeping them from happening or arising.
Sense 1 fits "keep from happening or arising".
Sense 2 is more about stopping someone/something from doing something or being in a certain state (e.g., prevent the cancer from spreading).
Wait, "prevent vomiting" -> keep vomiting from happening.
Let's check the examples for Sense 1: "My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project".
Wait, sense 1 is "keep from happening or arising; make impossible".
Sense 2 is "stop (someone or something) from doing something or being in a certain state".
"prevent dehydration" -> keep dehydration from happening.
Is it sense 1 or sense 2?
"prevent" in WordNet:
prevent%2:41:01:: keep from happening or arising; make impossible
prevent%2:41:00:: stop (someone or something) from doing something or being in a certain state

"prevent vomiting" -> keep vomiting from happening.
"prevent dehydration" -> keep dehydration from happening.
This aligns perfectly with "keep from happening or arising".
Let's choose sense 1.
Wait, let's look at the synonyms for sense 1: forestall, foreclose, preclude, forbid.
Synonyms for sense 2: keep.
"prevent dehydration" -> keep dehydration from happening.
Actually, "prevent" in the sense of "keep from happening or arising" is often used for events or states like vomiting, dehydration, disease, etc.
Let's consider "prevent" in WordNet.
Sense 1: keep from happening or arising; make impossible.
Sense 2: stop (someone or something) from doing something or being in a certain state.
"prevent vomiting" -> keep vomiting from happening.
I will go with sense 1.
Wait, let's re-read the examples for sense 1: "My sense of tact forbids an honest answer; Your role in the projects precludes your involvement in the competitive project".
Examples for sense 2: "We must prevent the cancer from spreading; His snoring kept me from falling asleep".
"prevent dehydration" is more like "keep from happening or arising".
Let's choose 1.
Wait, "prevent" (keep from happening or arising) is sense 1.
Let's double check.
"prevent vomiting" -> keep vomiting from happening.
Yes, sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dehydration
Target surface form: dehydration
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent <t>dehydration</t>) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dehydration%1:26:00:: | definition=dryness resulting from the removal of water | synonyms=desiccation
2. sense_key=dehydration%1:26:01:: | definition=depletion of bodily fluids
3. sense_key=dehydration%1:22:00:: | definition=the process of extracting moisture | synonyms=desiccation, drying up, evaporation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "dehydration".
Context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The context is about medical treatment, specifically giving fluids to prevent the depletion of bodily fluids in a patient.
Candidate senses:
1. dryness resulting from the removal of water (desiccation)
2. depletion of bodily fluids
3. the process of extracting moisture (desiccation, drying up, evaporation)

Sense 2 is "depletion of bodily fluids", which perfectly matches the medical context of giving fluids to a patient to prevent dehydration.

Therefore, the best indexed sense is 2.
I will return {"sense_index": 2}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is about administering a drug (Alimta) to a patient.
"Alimta should only be given under the supervision of a doctor..."
"It is given once every three weeks as an intravenous infusion..."
"When Alimta is given with cisplatin, an anti-emetic medicine... and fluids... should also be given before or after the cisplatin dose."

The target word is "given" in the context of administering medicine.
Let's look at the candidate senses.
Sense 19: give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug

This perfectly matches the context of giving a drug/medicine.
Let's double check.
"give (as medicine)" -> "I gave him the drug"
Context: "Alimta should only be given under the supervision of a doctor..."
"given" here means administered as medicine.

Sense 19 is the exact match.
Let's review the options.
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug

Yes, this is the one.
Context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose."
This is giving medicine.
Sense 19 is the best fit.
I will return {"sense_index": 19}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: before
Target surface form: before
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=before%4:02:03:: | definition=earlier in time; previously | synonyms=earlier | examples=I had known her before; as I said before
2. sense_key=before%4:02:01:: | definition=at or in the front | synonyms=ahead, in front | examples=I see the lights of a town ahead; the road ahead is foggy

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "before".
Context: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
The word "before" here means earlier in time, previously, or prior to the cisplatin dose.
Candidate senses:
1. sense_key=before%4:02:03:: | definition=earlier in time; previously | synonyms=earlier | examples=I had known her before; as I said before
2. sense_key=before%4:02:01:: | definition=at or in the front | synonyms=ahead, in front | examples=I see the lights of a town ahead; the road ahead is foggy

Sense 1 fits perfectly, as it refers to time (earlier in time).
Sense 2 refers to space (at or in the front).

Therefore, the best indexed sense is 1.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: after
Target surface form: after
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=after%4:02:01:: | definition=happening at a time subsequent to a reference time | synonyms=subsequently, later, afterwards, afterward, later on | examples=he apologized subsequently; he's going to the store but he'll be back here later
2. sense_key=after%4:02:00:: | definition=behind or in the rear | examples=and Jill came tumbling after

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "after".
Context: "...should also be given before or after the cisplatin dose."
This means happening at a time subsequent to a reference time (the cisplatin dose).
Sense 1: happening at a time subsequent to a reference time. Synonyms: subsequently, later, afterwards, afterward, later on.
Sense 2: behind or in the rear.

The context clearly refers to time (before or after the dose).
Therefore, sense 1 is the correct sense.
I will return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "dose" in the context of "cisplatin <t>dose</t>".
The context is about medical treatment, specifically chemotherapy (Alimta, cisplatin).
The sentence says: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."
Here, "dose" refers to the quantity of an active agent (cisplatin) taken in or absorbed at any one time.
Let's look at the candidate senses:
1. dose%1:06:00:: - a measured portion of medicine taken at any one time
2. dose%1:23:00:: - the quantity of an active agent (substance or radiation) taken in or absorbed at any one time
3. dose%1:26:00:: - a communicable infection transmitted by sexual intercourse
4. dose%1:06:01:: - street name for lysergic acid diethylamide

Wait, "cisplatin dose" refers to the quantity of the active agent (cisplatin) administered.
Is it sense 1 or sense 2?
Sense 1: a measured portion of medicine taken at any one time.
Sense 2: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time.
In WordNet, "dose" as a quantity of an active agent (substance or radiation) is sense 2.
Let's check the context: "the cisplatin dose". Cisplatin is an active agent (substance).
Wait, "dose" in "cisplatin dose" could be sense 2.
Let's re-read the definitions.
1. a measured portion of medicine taken at any one time
2. the quantity of an active agent (substance or radiation) taken in or absorbed at any one time

Actually, "dose" in "cisplatin dose" is the quantity of the active agent.
Let's see: "the recommended dose of Alimta is 500 mg per square metre..."
"before or after the cisplatin dose."
Is it 1 or 2?
In WordNet, "dose" (quantity of an active agent) is often used for radiation or chemical substances.
Let's check WordNet for "dose".
dose.n.01: a measured portion of medicine taken at any one time
dose.n.02: the quantity of an active agent (substance or radiation) taken in or absorbed at any one time

Wait, "cisplatin" is a medicine, but it's also an active agent.
Let's look at similar examples. "radiation dose" -> sense 2.
"medicine dose" -> sense 1.
But "cisplatin" is a medicine. However, "active agent (substance or radiation)" fits "cisplatin" well.
Let's consider "dose" in "cisplatin dose".
Is it 1 or 2?
Let's search for "dose" in medical contexts. "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time" is often used for things like "lethal dose", "radiation dose", "toxic dose".
"a measured portion of medicine taken at any one time" is for "take a dose of cough syrup".
Here, "cisplatin dose" refers to the administration of the substance.
Wait, let's look at the synonyms.
Sense 1: dosage
Sense 2: dosage
Both have dosage as a synonym.
Let's look at the exact wording: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".
"cisplatin" is a substance.
Let's choose sense 2 because "cisplatin" is an active agent/substance, and "dose" here refers to the quantity administered.
Wait, let's re-evaluate. "a measured portion of medicine taken at any one time" vs "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".
In the sentence: "before or after the cisplatin dose."
Could it be 2? Yes, "active agent (substance or radiation)".
Let's check if there is a more specific match.
"cisplatin" is a chemical substance used in chemotherapy.
I will go with 2.
Wait, let's think if 1 is better. "medicine" is explicitly in 1. Cisplatin is a medicine.
But "active agent (substance or radiation)" is more technical and fits "cisplatin" (a chemical substance).
Let's choose 2.
Actually, in many WSD datasets, "dose" of a specific chemical or radiation is sense 2.
Let's choose 2.
Wait, "dose" in "cisplatin dose" -> "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time".
Let's double check.
"the recommended dose of Alimta is 500 mg..." -> this is a measured portion of medicine.
"before or after the cisplatin dose" -> this is the quantity of the active agent.
I'll output 2.
Let's reconsider 1. "a measured portion of medicine taken at any one time". Cisplatin is a medicine.
But "active agent (substance or radiation)" is a broader and more precise fit for "cisplatin" in a chemotherapy context where it's referred to as an active agent.
I will bet on 2.
Let's review the prompt: "Do not answer with a WordNet sense key. Return only a JSON object exactly like {"sense_index": 3}."
I will output {"sense_index": 2}.
Wait, is "cisplatin" considered a medicine or an active agent? It's both, but "active agent (substance or radiation)" is the exact definition for dose in pharmacology/toxicology when referring to the substance itself.
Let's go with 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: Treatment
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. <t>Treatment</t> should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "Treatment" in the context of medical care: "To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. ... Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
This clearly refers to medical procedures or applications intended to relieve illness or injury.
Sense 1: care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention.
Sense 2: the management of someone or something.
Sense 3: a manner of dealing with something artistically.
Sense 4: an extended communication.

Sense 1 is the best fit.
I will return {"sense_index": 1}.