[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancers
Context:
The team used a battery of the newly developed "gene probes, "snippets of genetic material that can track a gene's presence in a cell. By analyzing cells extracted from eye tumors, they found defects in the second copy of chromosome 13 in the exact area as in the first copy of the chromosome. The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all <t>cancers</t>. "It was an audacious claim.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context discusses genetic research on retinoblastoma and cancers in general - clearly the medical/disease sense.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: audacious
Target surface form: audacious
Context:
By analyzing cells extracted from eye tumors, they found defects in the second copy of chromosome 13 in the exact area as in the first copy of the chromosome. The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an <t>audacious</t> claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers.

Candidate senses:
1. sense_key=audacious%5:00:00:bold:00 | definition=invulnerable to fear or intimidation | synonyms=brave, dauntless, fearless, hardy, intrepid, unfearing | examples=audacious explorers; fearless reporters and photographers
2. sense_key=audacious%5:00:00:unashamed:00 | definition=unrestrained by convention or propriety; ; ; - Los Angeles Times; ; ; - Bertrand Russell | synonyms=barefaced, bodacious, bald-faced, brassy, brazen, brazen-faced | examples=an audacious trick to pull; a barefaced hypocrite
3. sense_key=audacious%5:00:00:adventurous:00 | definition=disposed to venture or take risks | synonyms=daring, venturesome, venturous | examples=audacious visions of the total conquest of space; an audacious interpretation of two Jacobean dramas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output: {"sense_index": 3}{"sense_index": 3}

finish_reason: stop

content: {"sense_index": 3}{"sense_index": 3}

role: assistant

reasoning_content: The context describes a "claim" that was audacious. The claim was that the two-hit hypothesis for retinoblastoma would apply to all cancers. This is a bold, daring claim - one that ventures beyond established knowledge. It's not about being unashamed or brazen (sense 2), nor is it about being brave or fearless in the face of danger (sense 1). It's about being disposed to take risks in one's intellectual or theoretical assertions. Sense 3, "disposed to venture or take risks," fits best here.

format: unknown

native_finish_reason: stop

provider: AtlasCloud

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: audacious
Target surface form: audacious
Context:
By analyzing cells extracted from eye tumors, they found defects in the second copy of chromosome 13 in the exact area as in the first copy of the chromosome. The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an <t>audacious</t> claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers.

Candidate senses:
1. sense_key=audacious%5:00:00:bold:00 | definition=invulnerable to fear or intimidation | synonyms=brave, dauntless, fearless, hardy, intrepid, unfearing | examples=audacious explorers; fearless reporters and photographers
2. sense_key=audacious%5:00:00:unashamed:00 | definition=unrestrained by convention or propriety; ; ; - Los Angeles Times; ; ; - Bertrand Russell | synonyms=barefaced, bodacious, bald-faced, brassy, brazen, brazen-faced | examples=an audacious trick to pull; a barefaced hypocrite
3. sense_key=audacious%5:00:00:adventurous:00 | definition=disposed to venture or take risks | synonyms=daring, venturesome, venturous | examples=audacious visions of the total conquest of space; an audacious interpretation of two Jacobean dramas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

[Assistant] {"sense_index": 3}{"sense_index": 3}

[User] Your previous answer was invalid. Choose one candidate index between 1 and 3. Return only valid JSON exactly like {"sense_index": 1}.

content: {"sense_index": 3}{"sense_index": 3}

reasoning_content: The context describes Dr. Knudson's claim that the retinoblastoma findings would be true for all cancers. This is described as "audacious" - meaning bold, daring, venturesome. The claim was bold and risky, taking a leap from one specific cancer to all cancers. This fits sense 3: "disposed to venture or take risks" with synonyms daring, venturesome, venturous.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: claim
Target surface form: claim
Context:
By analyzing cells extracted from eye tumors, they found defects in the second copy of chromosome 13 in the exact area as in the first copy of the chromosome. The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious <t>claim</t>. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers.

Candidate senses:
1. sense_key=claim%1:10:00:: | definition=an assertion of a right (as to money or property) | examples=his claim asked for damages
2. sense_key=claim%1:10:02:: | definition=an assertion that something is true or factual | examples=his claim that he was innocent; evidence contradicted the government's claims
3. sense_key=claim%1:04:00:: | definition=demand for something as rightful or due | examples=they struck in support of their claim for a shorter work day
4. sense_key=claim%1:07:02:: | definition=an informal right to something | synonyms=title | examples=his claim on her attentions; his title to fame
5. sense_key=claim%1:07:01:: | definition=an established or recognized right | synonyms=title | examples=a strong legal claim to the property; he had no documents confirming his title to his father's estate
6. sense_key=claim%1:10:01:: | definition=a demand especially in the phrase | synonyms=call | examples=the call of duty

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context describes Dr. Knudson making an "audacious claim" - asserting that what was true of retinoblastoma would be true for all cancers. This is an assertion that something is true or factual.

Sense 2 matches: "an assertion that something is true or factual" with examples like "his claim that he was innocent; evidence contradicted the government's claims."

This is clearly sense 2.

provider: Novita


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: young
Target surface form: young
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a <t>young</t> molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=young%3:00:00:: | definition=(used of living things especially persons) in an early period of life or development or growth | synonyms=immature | examples=young people
2. sense_key=young%5:00:00:early:02 | definition=(of crops) harvested at an early stage of development; before complete maturity | synonyms=new | examples=new potatoes; young corn
3. sense_key=young%5:00:01:young:00 | definition=suggestive of youth; vigorous and fresh | synonyms=youthful, vernal | examples=he is young for his age
4. sense_key=young%5:00:00:new:00 | definition=being in its early stage | examples=a young industry; the day is still young
5. sense_key=young%5:00:00:inexperienced:00 | definition=not tried or tested by experience | synonyms=unseasoned, untested, untried | examples=unseasoned artillery volunteers; still untested in battle

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The target word "young" is used to describe Dr. Vogelstein as "a young molecular biologist." This refers to a person in an early period of life or development. The most appropriate sense is sense 1, which deals with living things (especially persons) in an early period of life or development.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: believe
Target surface form: believed
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, <t>believed</t> Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=believe%2:31:00:: | definition=accept as true; take to be true | examples=I believed his report; We didn't believe his stories from the War
2. sense_key=believe%2:31:04:: | definition=judge or regard; look upon; judge | synonyms=think, consider, conceive | examples=I think he is very smart; I believe her to be very smart
3. sense_key=believe%2:31:03:: | definition=be confident about something | synonyms=trust | examples=I believe that he will come back from the war
4. sense_key=believe%2:31:01:: | definition=follow a credo; have a faith; be a believer | examples=When you hear his sermons, you will be able to believe, too
5. sense_key=believe%2:31:02:: | definition=credit with veracity | examples=You cannot believe this man; Should we believe a publication like the National Enquirer?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The sentence is: "Dr. Vogelstein... believed Dr. Knudson was right, and set out to repeat the Cavenee experiment..."

Here, "believed" means that Dr. Vogelstein accepted as true that Dr. Knudson was right. He took Dr. Knudson's claim to be true and acted on it by repeating the experiment.

Let me look at the candidate senses:

1. "accept as true; take to be true" - This fits well. Dr. Vogelstein accepted Dr. Knudson's claim as true.
2. "judge or regard; look upon; judge" - This is about forming a judgment about something, often with "to be" (e.g., "I believe her to be very smart"). The construction "believed Dr. Knudson was right" could also fit here.
3. "be confident about something" - More about confidence in a future event.
4. "follow a credo; have a faith" - About religious belief.
5. "credit with veracity" - Similar to sense 1, but more about whether to trust a person/source.

The distinction between sense 1 and sense 5: Sense 1 is "accept as true; take to be true" (about a proposition/statement), while sense 5 is "credit with veracity" (about a person/source). The sentence says "believed Dr. Knudson was right" - this is about accepting a proposition (that Knudson was right) as true. Sense 1 seems most fitting.

Sense 2 involves judging regarding someone in a certain way, like "I believe him to be honest." The construction here "believed Dr. Knudson was right" is more about accepting the truth of the claim rather than judging Knudson himself.

So sense 1 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: right
Target surface form: right
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was <t>right</t>, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=right%3:00:00:: | definition=being or located on or directed toward the side of the body to the east when facing north | examples=my right hand; right center field
2. sense_key=right%3:00:02:: | definition=free from error; especially conforming to fact or truth | synonyms=correct | examples=the correct answer; the correct version
3. sense_key=right%5:00:01:proper:00 | definition=socially right or correct | synonyms=correct | examples=it isn't right to leave the party without saying goodbye; correct behavior
4. sense_key=right%3:00:01:: | definition=in conformance with justice or law or morality | examples=do the right thing and confess
5. sense_key=right%3:00:04:: | definition=correct in opinion or judgment | synonyms=correct | examples=time proved him right
6. sense_key=right%5:00:00:appropriate:00 | definition=appropriate for a condition or purpose or occasion or a person's character, needs | synonyms=proper | examples=everything in its proper place; the right man for the job
7. sense_key=right%3:00:03:: | definition=of or belonging to the political or intellectual right
8. sense_key=right%5:00:00:satisfactory:00 | definition=in or into a satisfactory condition | examples=things are right again now; put things right
9. sense_key=right%5:00:00:right-handed:00 | definition=intended for the right hand | synonyms=right-hand | examples=a right-hand glove
10. sense_key=right%5:00:02:proper:00 | definition=in accord with accepted standards of usage or procedure | synonyms=correct | examples=what's the right word for this?; the right way to open oysters
11. sense_key=right%5:00:00:perpendicular:00 | definition=having the axis perpendicular to the base | examples=a right angle
12. sense_key=right%5:00:00:outside:00 | definition=(of the side of cloth or clothing) facing or intended to face outward | examples=the right side of the cloth showed the pattern; be sure your shirt is right side out
13. sense_key=right%5:00:00:opportune:00 | definition=most suitable or right for a particular purpose | synonyms=good, ripe | examples=a good time to plant tomatoes; the right time to act
14. sense_key=right%5:00:00:accurate:00 | definition=precisely accurate | synonyms=veracious | examples=a veracious account

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context is: "believed Dr. Knudson was right, and set out to repeat the Cavenee experiment"

Here "right" means "correct" - Dr. Vogelstein believed Dr. Knudson was correct in his claim. The example for sense 5 is "time proved him right" which closely matches this pattern. Sense 2 is "free from error; especially conforming to fact or truth" with the example "the correct answer; the correct version." Sense 5 is "correct in opinion or judgment" with the example "time proved him right."

The pattern "believed he was right" / "proved him right" both match sense 5 well - it's about being correct in one's opinion or judgment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: set_out
Target surface form: set out
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and <t>set out</t> to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=set_out%2:30:00:: | definition=take the first step or steps in carrying out an action | synonyms=get down, begin, get, start out, start, set about | examples=We began working at dawn; Who will start?
2. sense_key=set_out%2:35:00:: | definition=lay out orderly or logically in a line or as if in a line | synonyms=range, array, lay out | examples=lay out the clothes; lay out the arguments
3. sense_key=set_out%2:38:00:: | definition=leave | synonyms=depart, part, start, start out, set forth, set off | examples=The family took off for Florida

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about Dr. Vogelstein who "set out to repeat the Cavenee experiment." This means he began or undertook the experiment. This matches sense 1: "take the first step or steps in carrying out an action" with synonyms like get down, begin, start out, start, set about.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: repeat
Target surface form: repeat
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to <t>repeat</t> the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=repeat%2:32:00:: | definition=to say, state, or perform again | synonyms=reiterate, ingeminate, iterate, restate, retell | examples=She kept reiterating her request
2. sense_key=repeat%2:36:00:: | definition=make or do or perform again | synonyms=duplicate, reduplicate, double, replicate | examples=He could never replicate his brilliant performance of the magic trick
3. sense_key=repeat%2:30:00:: | definition=happen or occur again | synonyms=recur | examples=This is a recurring story
4. sense_key=repeat%2:32:01:: | definition=to say again or imitate | synonyms=echo | examples=followers echoing the cries of their leaders
5. sense_key=repeat%2:41:00:: | definition=do over | synonyms=take over | examples=They would like to take it over again
6. sense_key=repeat%2:36:01:: | definition=repeat an earlier theme of a composition | synonyms=reprise, reprize, recapitulate

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output: {"sense_index": 2}{"sense_index": 2}

content: {"sense_index": 2}{"sense_index": 2}

reasoning_content: The target word "repeat" is used in the context of repeating the Cavenee experiment. This means to perform the experiment again, to replicate it. The synonyms "duplicate, reduplicate, double, replicate" fit perfectly here. This corresponds to sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: repeat
Target surface form: repeat
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to <t>repeat</t> the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=repeat%2:32:00:: | definition=to say, state, or perform again | synonyms=reiterate, ingeminate, iterate, restate, retell | examples=She kept reiterating her request
2. sense_key=repeat%2:36:00:: | definition=make or do or perform again | synonyms=duplicate, reduplicate, double, replicate | examples=He could never replicate his brilliant performance of the magic trick
3. sense_key=repeat%2:30:00:: | definition=happen or occur again | synonyms=recur | examples=This is a recurring story
4. sense_key=repeat%2:32:01:: | definition=to say again or imitate | synonyms=echo | examples=followers echoing the cries of their leaders
5. sense_key=repeat%2:41:00:: | definition=do over | synonyms=take over | examples=They would like to take it over again
6. sense_key=repeat%2:36:01:: | definition=repeat an earlier theme of a composition | synonyms=reprise, reprize, recapitulate

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

[Assistant] {"sense_index": 2}{"sense_index": 2}

[User] Your previous answer was invalid. Choose one candidate index between 1 and 6. Return only valid JSON exactly like {"sense_index": 1}.

content: {"sense_index": 2}{"sense_index": 2}

reasoning_content: The context is about Dr. Vogelstein setting out to "repeat" the Cavenee experiment. This means to do the experiment again, to replicate it. Sense 2: "make or do or perform again" with synonyms duplicate, reduplicate, double, replicate - this fits perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: experiment
Target surface form: experiment
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee <t>experiment</t> in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=experiment%1:04:00:: | definition=the act of conducting a controlled test or investigation | synonyms=experimentation
2. sense_key=experiment%1:09:00:: | definition=the testing of an idea | synonyms=experimentation | examples=it was an experiment in living; not all experimentation is done in laboratories
3. sense_key=experiment%1:04:01:: | definition=a venture at something new or different | examples=as an experiment he decided to grow a beard

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about a scientific research setting where Dr. Vogelstein set out to "repeat the Cavenee experiment" — this refers to a controlled scientific test/investigation. Sense 1 matches: "the act of conducting a controlled test or investigation."

provider: Minimax


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cells
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in <t>cells</t> from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from <t>other</t> cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word "other" appears in the phrase "other cancers." The context is about Dr. Vogelstein setting out to repeat an experiment in cells from other cancers (i.e., cancers other than retinoblastoma). This means "other" here refers to "not the same one or ones already mentioned or implied" — i.e., different cancers from retinoblastoma.

This matches sense 1: "not the same one or ones already mentioned or implied."

The other senses don't fit:
- Sense 2 is about "recently past" (like "the other evening")
- Sense 3 is about "belonging to the distant past" (like "former")
- Sense 4 is about "very unusual; different in character or quality"

So sense 1 is the best match.

provider: Parasail


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancers
Context:
The finding riveted medicine. It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other <t>cancers</t>. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about medical research on cancer, specifically about retinoblastoma, Wilm's tumor, and genetic mutations leading to cancers. The word "cancers" here refers to malignant growths/tumors, which matches sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: team
Target surface form: teams
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research <t>teams</t> in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=team%1:14:00:: | definition=a cooperative unit (especially in sports) | synonyms=squad
2. sense_key=team%1:14:01:: | definition=two or more draft animals that work together to pull something

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about research teams working in a scientific setting. The word "teams" refers to groups of researchers working together. This is closest to sense 1, which is "a cooperative unit (especially in sports)" - while the gloss mentions sports, the broader meaning is a cooperative unit, which fits research teams. Sense 2 refers to draft animals, which is not appropriate here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: report
Target surface form: report
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to <t>report</t> dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=report%2:32:00:: | definition=to give an account or representation of in words | synonyms=describe, account | examples=Discreet Italian police described it in a manner typically continental
2. sense_key=report%2:32:04:: | definition=announce as the result of an investigation or experience or finding | examples=Dozens of incidents of wife beatings are reported daily in this city; The team reported significant advances in their research
3. sense_key=report%2:32:03:: | definition=announce one's presence | examples=I report to work every day at 9 o'clock
4. sense_key=report%2:32:01:: | definition=make known to the authorities | examples=One student reported the other to the principal
5. sense_key=report%2:32:13:: | definition=be responsible for reporting the details of, as in journalism | synonyms=cover | examples=Snow reported on China in the 1950's; The cub reporter covered New York City
6. sense_key=report%2:32:02:: | definition=complain about; make a charge against | examples=I reported her to the supervisor

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context: "His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor."

Here, "report" means to announce or make known the results of research/findings. This matches sense 2: "announce as the result of an investigation or experience or finding." The example "The team reported significant advances in their research" is very close to this context where research teams are reporting their findings about chromosome losses.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dual
Target surface form: dual
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report <t>dual</t> chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=dual%5:00:00:multiple:00 | definition=consisting of or involving two parts or components usually in pairs | synonyms=double, duple | examples=an egg with a double yolk; a double (binary) star
2. sense_key=dual%5:00:02:multiple:00 | definition=having more than one decidedly dissimilar aspects or qualities; ; - R.W.Emerson; -Frederick Harrison | synonyms=double, twofold, treble, threefold | examples=a double (or dual) role for an actor; the office of a clergyman is twofold; public preaching and private influence
3. sense_key=dual%5:00:00:plural:00 | definition=a grammatical number category referring to two items or units as opposed to one item (singular) or more than two items (plural) | examples=ancient Greek had the dual form but it has merged with the plural form in modern Greek

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output: {"sense_index": 1}{"sense_index": 1}

content: {"sense_index": 1}{"sense_index": 1}

reasoning_content:
The context says "report dual chromosome losses for a rare childhood cancer." Here, "dual" modifies "chromosome losses" meaning two chromosome losses. This is about two parts/components - two chromosome losses. This fits sense 1: "consisting of or involving two parts or components usually in pairs." The synonym "double" fits well - "double chromosome losses."

Sense 2 is about having more than one dissimilar aspect or quality (like a dual role for an actor), which doesn't fit as well here.

Sense 3 is about grammatical number, which doesn't apply.

The best fit is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dual
Target surface form: dual
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report <t>dual</t> chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=dual%5:00:00:multiple:00 | definition=consisting of or involving two parts or components usually in pairs | synonyms=double, duple | examples=an egg with a double yolk; a double (binary) star
2. sense_key=dual%5:00:02:multiple:00 | definition=having more than one decidedly dissimilar aspects or qualities; ; - R.W.Emerson; -Frederick Harrison | synonyms=double, twofold, treble, threefold | examples=a double (or dual) role for an actor; the office of a clergyman is twofold; public preaching and private influence
3. sense_key=dual%5:00:00:plural:00 | definition=a grammatical number category referring to two items or units as opposed to one item (singular) or more than two items (plural) | examples=ancient Greek had the dual form but it has merged with the plural form in modern Greek

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

[Assistant] {"sense_index": 1}{"sense_index": 1}

[User] Your previous answer was invalid. Choose one candidate index between 1 and 3. Return only valid JSON exactly like {"sense_index": 1}.

content: {"sense_index": 1}{"sense_index": 1}

reasoning_content: The context is about "dual chromosome losses" - meaning two chromosome losses, consisting of two parts. This matches sense 1: "consisting of or involving two parts or components usually in pairs" with synonyms "double, duple."


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: loss
Target surface form: losses
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome <t>losses</t> for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=loss%1:21:01:: | definition=something that is lost | examples=the car was a total loss; loss of livestock left the rancher bankrupt
2. sense_key=loss%1:22:00:: | definition=gradual decline in amount or activity | examples=weight loss; a serious loss of business
3. sense_key=loss%1:04:00:: | definition=the act of losing someone or something | examples=everyone expected him to win so his loss was a shock
4. sense_key=loss%1:07:00:: | definition=the disadvantage that results from losing something | synonyms=deprivation | examples=his loss of credibility led to his resignation; losing him is no great deprivation
5. sense_key=loss%1:11:01:: | definition=the experience of losing a loved one | examples=he sympathized on the loss of their grandfather
6. sense_key=loss%1:21:00:: | definition=the amount by which the cost of a business exceeds its revenue | synonyms=red ink, red | examples=the company operated at a loss last year; the company operated in the red last year
7. sense_key=loss%1:11:00:: | definition=military personnel lost by death or capture | synonyms=personnel casualty
8. sense_key=loss%1:11:02:: | definition=euphemistic expressions for death | synonyms=passing, departure, exit, expiration, going, release | examples=thousands mourned his passing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "losses" in the context: "His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor."

This is about genetic/chromosomal losses - meaning the loss or absence of chromosomes. The context is about cancer genetics, where the loss of gene copies (and chromosomes) leads to cancer. So "chromosome losses" refers to the loss of genetic material - chromosomes being lost or missing from cells.

Let me look at the candidate senses:

1. sense_key=loss%1:21:01:: | definition=something that is lost - This could fit. Chromosome losses = chromosomes that are lost.
2. sense_key=loss%1:22:00:: | definition=gradual decline in amount or activity - This doesn't fit well; it's not about gradual decline.
3. sense_key=loss%1:04:00:: | definition=the act of losing someone or something - This could also potentially fit.
4. sense_key=loss%1:07:00:: | definition=the disadvantage that results from losing something - Not the best fit.
5. sense_key=loss%1:11:01:: | definition=the experience of losing a loved one - No, not about death of a person.
6. sense_key=loss%1:21:00:: | definition=the amount by which the cost of a business exceeds its revenue - Financial, not relevant.
7. sense_key=loss%1:11:00:: | definition=military personnel lost by death or capture - Not military.
8. sense_key=loss%1:11:02:: | definition=euphemistic expressions for death - Not about death.

The context is about genetic material being lost - chromosomes that are lost from cells. This is closest to sense 1 (something that is lost) or sense 3 (the act of losing something).

"Chromosome losses" - in genetics, this refers to the loss of chromosomes, i.e., the chromosomes that are lost. This is more about "things that are lost" rather than "the act of losing."

Sense 1: "something that is lost" - examples: "the car was a total loss; loss of livestock left the rancher bankrupt"
Sense 3: "the act of losing someone or something" - examples: "everyone expected him to win so his loss was a shock"

In molecular biology, "chromosome losses" typically refers to the chromosomes that are lost (the event of losing them, or the lost chromosomes themselves).

Looking more carefully, sense 1 is "something that is lost" - this would mean the chromosomes that were lost. The phrase "dual chromosome losses" means two chromosomes were lost, i.e., the loss events or the lost chromosomes.

Actually, in scientific literature, "loss of heterozygosity" or "chromosome loss" typically refers to the event of losing a chromosome. But "chromosome losses" (plural) likely refers to multiple instances of chromosome loss.

I think sense 1 ("something that is lost") is the best fit because the chromosomes are the things being lost - they are the losses. This aligns with how the word is used in the sentence - reporting on the chromosome losses, which are the lost chromosomes.

Alternatively, sense 3 could work since it's the act of losing. But the examples for sense 3 are more about the emotional/social impact of losing (like losing a competition), while sense 1 is more about the concrete thing lost.

Given the scientific context where "chromosome losses" refers to specific genetic events/entities that are lost, sense 1 seems most appropriate.

I'll go with sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: childhood
Target surface form: childhood
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare <t>childhood</t> cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=childhood%1:28:00:: | definition=the time of person's life when they are a child
2. sense_key=childhood%1:26:00:: | definition=the state of a child between infancy and adolescence | synonyms=puerility

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The context says "a rare childhood cancer of the kidney called Wilm's tumor." Here, "childhood" is used as an adjective modifying "cancer," referring to a cancer that occurs in children - the time of a person's life when they are a child.

Sense 1: "the time of person's life when they are a child" - This refers to the period/era of being a child, which fits the use here as a modifier meaning "occurring during childhood."

Sense 2: "the state of a child between infancy and adolescence" with synonyms "puerility" - This emphasizes the state/condition of being a child, not the time period.

When "childhood" is used as an adjective modifier (childhood cancer), it refers to cancers that affect children, i.e., during the time of being a child. Sense 1 is more about the time period, which fits the attributive use better.

I'll go with sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood <t>cancer</t> of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about medical/scientific discussion of cancer as a disease - specifically discussing gene loss leading to cancer, retinoblastoma, Wilm's tumor, colon cancer, lung cancer. This clearly refers to the disease sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: call
Target surface form: called
Context:
It was the first time anyone had showed that the loss of both copies of the same gene could lead to the eruption of a cancer. "It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney <t>called</t> Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer.

Candidate senses:
1. sense_key=call%2:32:02:: | definition=assign a specified (usually proper) proper name to | synonyms=name | examples=They named their son David; The new school was named after the famous Civil Rights leader
2. sense_key=call%2:32:00:: | definition=ascribe a quality to or give a name of a common noun that reflects a quality | examples=He called me a bastard; She called her children lazy and ungrateful
3. sense_key=call%2:32:01:: | definition=get or try to get into communication (with someone) by telephone | synonyms=telephone, call up, phone, ring | examples=I tried to call you all night; Take two aspirin and call me in the morning
4. sense_key=call%2:32:09:: | definition=utter a sudden loud cry | synonyms=shout, shout out, cry, yell, scream, holler | examples=she cried with pain when the doctor inserted the needle; I yelled to her from the window but she couldn't hear me
5. sense_key=call%2:32:05:: | definition=order, request, or command to come | synonyms=send for | examples=She was called into the director's office; Call the police!
6. sense_key=call%2:41:00:: | definition=pay a brief visit | synonyms=visit, call in | examples=The mayor likes to call on some of the prominent citizens
7. sense_key=call%2:41:04:: | definition=call a meeting; invite or command to meet | examples=The Wannsee Conference was called to discuss the `Final Solution'; The new dean calls meetings every week
8. sense_key=call%2:32:13:: | definition=read aloud to check for omissions or absentees | examples=Call roll
9. sense_key=call%2:32:04:: | definition=send a message or attempt to reach someone by radio, phone, etc.; make a signal to in order to transmit a message | examples=Hawaii is calling!; A transmitter in Samoa was heard calling
10. sense_key=call%2:32:03:: | definition=utter a characteristic note or cry | examples=bluejays called to one another
11. sense_key=call%2:42:09:: | definition=stop or postpone because of adverse conditions, such as bad weather | examples=call a football game
12. sense_key=call%2:41:14:: | definition=greet, as with a prescribed form, title, or name | synonyms=address | examples=He always addresses me with `Sir'; Call me Mister
13. sense_key=call%2:41:12:: | definition=make a stop in a harbour | examples=The ship will call in Honolulu tomorrow
14. sense_key=call%2:40:09:: | definition=demand payment of (a loan) | synonyms=call in | examples=Call a loan
15. sense_key=call%2:40:05:: | definition=make a demand, as for a card or a suit or a show of hands | synonyms=bid | examples=He called his trump
16. sense_key=call%2:38:00:: | definition=give the calls (to the dancers) for a square dance | synonyms=call off
17. sense_key=call%2:32:06:: | definition=indicate a decision in regard to | examples=call balls and strikes behind the plate
18. sense_key=call%2:32:10:: | definition=make a prediction about; tell in advance | synonyms=predict, foretell, prognosticate, forebode, anticipate, promise | examples=Call the outcome of an election
19. sense_key=call%2:32:12:: | definition=require the presentation of for redemption before maturation | examples=Call a bond
20. sense_key=call%2:32:07:: | definition=challenge (somebody) to make good on a statement; charge with or censure for an offense | examples=He deserves to be called on that
21. sense_key=call%2:32:08:: | definition=declare in the capacity of an umpire or referee | examples=call a runner out
22. sense_key=call%2:32:11:: | definition=lure by imitating the characteristic call of an animal | examples=Call ducks
23. sense_key=call%2:32:15:: | definition=order or request or give a command for | examples=The unions called a general strike for Sunday
24. sense_key=call%2:32:14:: | definition=order, summon, or request for a specific duty or activity, work, role | examples=He was already called 4 times for jury duty; They called him to active military duty
25. sense_key=call%2:31:13:: | definition=utter in a loud voice or announce | examples=He called my name; The auctioneer called the bids
26. sense_key=call%2:31:00:: | definition=challenge the sincerity or truthfulness of | examples=call the speaker on a question of fact
27. sense_key=call%2:31:05:: | definition=consider or regard as being | examples=I would not call her beautiful
28. sense_key=call%2:29:05:: | definition=rouse somebody from sleep with a call | examples=I was called at 5 A.M. this morning

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "called" in the phrase "a rare childhood cancer of the kidney called Wilm's tumor."

This is a past participle used as an adjective, meaning "named" or "known as." The cancer is named "Wilm's tumor."

Looking at the candidate senses:

1. sense_key=call%2:32:02:: | definition=assign a specified (usually proper) proper name to | synonyms=name | examples=They named their son David; The new school was named after the famous Civil Rights leader

This is the best match. "Called Wilm's tumor" means "named Wilm's tumor." The definition "assign a specified (usually proper) proper name to" fits perfectly, and the synonym "name" is exactly right.

Sense 2 is about ascribing a quality or giving a common noun name - not quite right.
Sense 12 is about greeting with a prescribed form - not right.

Sense 1 is clearly the best match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: turn_to
Target surface form: turned
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next <t>turned</t> his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=turn_to%2:32:01:: | definition=speak to | synonyms=address | examples=He addressed the crowd outside the window
2. sense_key=turn_to%2:30:00:: | definition=direct one's interest or attention towards; go into | examples=The pedophile turned to boys for satisfaction; People turn to mysticism at the turn of a millennium

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The target is "turned" from "turn_to". The context says "Dr. Vogelstein next turned his attention [to] colon cancer". This means he directed his attention toward colon cancer. That matches sense 2: "direct one's interest or attention towards; go into".


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: second
Target surface form: second
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the <t>second</t> biggest cancer killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=second%5:00:00:ordinal:00 | definition=coming next after the first in position in space or time or degree or magnitude | synonyms=2nd, 2d
2. sense_key=second%3:00:00:: | definition=a part or voice or instrument or orchestra section lower in pitch than or subordinate to the first | examples=second flute; the second violins

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word "second" in the context "the second biggest cancer killer in the U.S. after lung cancer" is used as an ordinal number meaning it comes after the first (lung cancer). This matches sense 1: "coming next after the first in position in space or time or degree or magnitude."

Sense 2 is about musical parts/instruments, which doesn't fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: big
Target surface form: biggest
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second <t>biggest</t> cancer killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=big%3:00:01:: | definition=above average in size or number or quantity or magnitude or extent | synonyms=large | examples=a large city; set out for the big city
2. sense_key=big%5:00:00:important:00 | definition=significant | examples=graduation was a big day in his life
3. sense_key=big%5:00:00:intense:00 | definition=very intense | synonyms=bad | examples=a bad headache; in a big rage
4. sense_key=big%5:00:00:loud:00 | definition=loud and firm | examples=a big voice; big bold piano sounds
5. sense_key=big%5:00:00:conspicuous:00 | definition=conspicuous in position or importance | synonyms=large, prominent | examples=a big figure in the movement; big man on campus
6. sense_key=big%5:00:00:intemperate:00 | definition=prodigious | synonyms=heavy | examples=big spender; big eater
7. sense_key=big%5:00:02:proud:00 | definition=exhibiting self-importance | synonyms=boastful, braggart, bragging, braggy, cock-a-hoop, crowing | examples=big talk
8. sense_key=big%5:00:00:proud:00 | definition=feeling self-importance | synonyms=swelled, vainglorious | examples=too big for his britches; had a swelled head
9. sense_key=big%5:00:00:mature:01 | definition=(of animals) fully developed | synonyms=adult, full-grown, fully grown, grown, grownup | examples=an adult animal; a grown woman
10. sense_key=big%5:00:00:heavy:08 | definition=marked by intense physical force | examples=a big wind
11. sense_key=big%5:00:00:generous:02 | definition=generous and understanding and tolerant | synonyms=large, magnanimous | examples=a heart big enough to hold no grudges; that's very big of you to be so forgiving
12. sense_key=big%5:00:00:generous:01 | definition=given or giving freely | synonyms=bighearted, bounteous, bountiful, freehanded, handsome, giving | examples=was a big tipper; the bounteous goodness of God
13. sense_key=big%5:00:00:pregnant:00 | definition=in an advanced stage of pregnancy | synonyms=enceinte, expectant, gravid, great, large, heavy | examples=was big with child; was great with child

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The word "biggest" in the context refers to "the second biggest cancer killer" - meaning the second largest/most significant in terms of mortality. This is about magnitude/extent, so sense 1 (above average in size or number or quantity or magnitude or extent) fits best.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest <t>cancer</t> killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content: {"sense_index": 1}{"sense_index": 1}

reasoning_content: The context discusses Dr. Vogelstein turning his attention to colon cancer, the second biggest cancer killer in the U.S. after lung cancer. This is clearly about cancer as a disease - a malignant growth/tumor. The sense that best matches is sense 1: "any malignant growth or tumor caused by abnormal and uncontrolled cell division."


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest <t>cancer</t> killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

[Assistant] {"sense_index": 1}{"sense_index": 1}

[User] Your previous answer was invalid. Choose one candidate index between 1 and 5. Return only valid JSON exactly like {"sense_index": 1}.

content: {"sense_index": 1}{"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: killer
Target surface form: killer
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer <t>killer</t> in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=killer%1:18:00:: | definition=someone who causes the death of a person or animal | synonyms=slayer
2. sense_key=killer%1:26:00:: | definition=the causal agent resulting in death | synonyms=cause of death | examples=heart disease is the biggest killer in the United States
3. sense_key=killer%1:09:00:: | definition=a difficulty that is hard to deal with | examples=that exam was a real killer
4. sense_key=killer%1:05:00:: | definition=predatory black-and-white toothed whale with large dorsal fin; common in cold seas | synonyms=killer whale, orca, grampus, sea wolf, Orcinus orca

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about colon cancer being the "second biggest cancer killer in the U.S. after lung cancer." This refers to cancer as a cause of death - the causal agent resulting in death. The example given for sense 2 is "heart disease is the biggest killer in the United States," which matches this usage perfectly.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: u.s.
Target surface form: U.S.
Context:
"It was extraordinarily satisfying, "says Dr. Knudson, now at Fox Chase Cancer Research Center in Philadelphia. "I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the <t>U.S.</t> after lung cancer. He believed colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages.

Candidate senses:
1. sense_key=u.s.%1:14:00:: | definition=the executive and legislative and judicial branches of the federal government of the United States | synonyms=United States government, United States, U.S. government
2. sense_key=us%1:15:00:: | definition=North American republic containing 50 states - 48 conterminous states in North America plus Alaska in northwest North America and the Hawaiian Islands in the Pacific Ocean; achieved independence in 1776 | synonyms=United States, United States of America, America, the States, USA

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: The context is about cancer statistics in the U.S. - "the second biggest cancer killer in the U.S. after lung cancer." This refers to the country, not the government. So sense 2 (the country) is the correct one.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: believe
Target surface form: believed
Context:
"I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer. He <t>believed</t> colon cancer might also arise from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages. It often is preceded by the development of polyps in the bowel, which in some cases become increasingly malignant in identifiable stages -- progressing from less severe to deadly -- as though a cascade of genetic damage might be occurring.

Candidate senses:
1. sense_key=believe%2:31:00:: | definition=accept as true; take to be true | examples=I believed his report; We didn't believe his stories from the War
2. sense_key=believe%2:31:04:: | definition=judge or regard; look upon; judge | synonyms=think, consider, conceive | examples=I think he is very smart; I believe her to be very smart
3. sense_key=believe%2:31:03:: | definition=be confident about something | synonyms=trust | examples=I believe that he will come back from the war
4. sense_key=believe%2:31:01:: | definition=follow a credo; have a faith; be a believer | examples=When you hear his sermons, you will be able to believe, too
5. sense_key=believe%2:31:02:: | definition=credit with veracity | examples=You cannot believe this man; Should we believe a publication like the National Enquirer?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "believed" in the context: "He believed colon cancer might also arise from multiple 'hits' on cancer suppressor genes, because it often seems to develop in stages."

This usage means "He thought/considered that colon cancer might also arise from multiple 'hits' on cancer suppressor genes." This is expressing an opinion or judgment about something.

Let me look at the candidate senses:

1. accept as true; take to be true - "I believed his report"
2. judge or regard; look upon; judge - "I think he is very smart; I believe her to be very smart" - synonyms: think, consider, conceive
3. be confident about something - "I believe that he will come back from the war"
4. follow a credo; have a faith; be a believer
5. credit with veracity - "You cannot believe this man"

The context here is about Dr. Vogelstein's scientific hypothesis/judgment that colon cancer might arise from multiple hits. This is more about his scientific reasoning/judgment rather than accepting something as true or being confident about it.

Sense 2 (judge or regard; think, consider) seems to fit best because the scientist is forming a hypothesis or judgment based on evidence. He's considering that colon cancer might arise from multiple genetic hits.

However, sense 1 (accept as true) could also work - he's accepting the hypothesis as true based on reasoning.

Sense 3 (be confident about something) - he's confident in the hypothesis.

The phrase "He believed colon cancer might also arise from..." - the "might" suggests he's hypothesizing/judging, not necessarily fully accepting as true. This aligns more with sense 2 (judge, regard, think, consider).

Actually, looking more carefully, "believed X might Y" is a hedge expressing a judgment. The scientist is considering this possibility. Sense 2 with synonyms "think, consider, conceive" fits well here.

I'll go with sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: arise
Target surface form: arise
Context:
"I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer. He believed colon cancer might also <t>arise</t> from multiple "hits "on cancer suppressor genes, because it often seems to develop in stages. It often is preceded by the development of polyps in the bowel, which in some cases become increasingly malignant in identifiable stages -- progressing from less severe to deadly -- as though a cascade of genetic damage might be occurring.

Candidate senses:
1. sense_key=arise%2:42:00:: | definition=come into existence; take on form or shape | synonyms=originate, rise, develop, uprise, spring up, grow | examples=A new religious movement originated in that country; a love that sprang up from friendship
2. sense_key=arise%2:42:01:: | definition=originate or come into being | synonyms=come up, bob up | examples=a question arose
3. sense_key=arise%2:38:00:: | definition=rise to one's feet | synonyms=rise, uprise, get up, stand up | examples=The audience got up and applauded
4. sense_key=arise%2:30:00:: | definition=result or issue | synonyms=come up | examples=A slight unpleasantness arose from this discussion
5. sense_key=arise%2:38:04:: | definition=move upward | synonyms=rise, lift, move up, go up, come up, uprise | examples=The fog lifted; The smoke arose from the forest fire
6. sense_key=arise%2:41:00:: | definition=take part in a rebellion; renounce a former allegiance | synonyms=rebel, rise, rise up
7. sense_key=arise%2:29:00:: | definition=get up and out of bed | synonyms=get up, turn out, uprise, rise | examples=I get up at 7 A.M. every day; They rose early

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The sentence is: "He believed colon cancer might also arise from multiple 'hits' on cancer suppressor genes, because it often seems to develop in stages."

Here, "arise" means "originate" or "come into being" - specifically, colon cancer arises from (originates from) multiple genetic hits. This is about something coming into existence or originating from a cause.

Let me look at the candidate senses:

1. sense_key=arise%2:42:00:: | definition=come into existence; take on form or shape | synonyms=originate, rise, develop, uprise, spring up, grow
2. sense_key=arise%2:42:01:: | definition=originate or come into being | synonyms=come up, bob up | examples=a question arose
3. sense_key=arise%2:38:00:: | definition=rise to one's feet - No
4. sense_key=arise%2:30:00:: | definition=result or issue | synonyms=come up | examples=A slight unpleasantness arose from this discussion
5. sense_key=arise%2:38:04:: | definition=move upward - No
6. sense_key=arise%2:41:00:: | definition=take part in a rebellion - No
7. sense_key=arise%2:29:00:: | definition=get up and out of bed - No

The candidates that fit are 1, 2, and 4.

Sense 1: "come into existence; take on form or shape" with synonyms like originate, develop, spring up, grow. This fits well because colon cancer comes into existence from genetic hits.

Sense 2: "originate or come into being" with example "a question arose." This also fits.

Sense 4: "result or issue" with example "A slight unpleasantness arose from this discussion." This also fits since colon cancer arises from (results from) genetic hits.

The difference between sense 1 and sense 2: Sense 1 seems to be about something coming into existence with a more physical/developmental connotation (take on form or shape, develop, grow). Sense 2 is more general "originate or come into being."

Sense 4 is specifically about resulting or issuing from something, with the "from" construction.

In the context, "colon cancer might also arise from multiple 'hits' on cancer suppressor genes" - this is about colon cancer originating/resulting from genetic damage. The "from" construction is important here.

Sense 4 specifically captures the "arise from" meaning where something results from a cause. The example "A slight unpleasantness arose from this discussion" is very similar to our context.

Sense 1 with "come into existence; take on form or shape" is also relevant.

Hmm, let me think more carefully. In WordNet:
- Sense 1 (arise%2:42:00) is about coming into existence generally
- Sense 2 (arise%2:42:01) is about originating or coming into being
- Sense 4 (arise%2:30:00) is about resulting or issuing

The context "arise from" is most naturally captured by sense 4 "result or issue" since the sentence structure is specifically "arise from" (causal). But sense 1 also has "originate" as a synonym, which captures similar meaning.

Actually, looking more carefully, sense 1's definition "come into existence; take on form or shape" with synonyms including "originate" is a strong match. But sense 4 is specifically about causation/result.

For "arise from" in the context of cancer resulting from genetic mutations, I think sense 4 (result or issue) is the best fit because it specifically captures the "arise from" causal construction.

Wait, let me reconsider. Sense 1 has "originate" as a synonym. "Cancer originates from genetic hits" is a very natural way to say it. And sense 1's definition is "come into existence" which is about the thing itself coming to be.

Sense 4's example is "A slight unpleasantness arose from this discussion" - this is about something negative resulting from a situation.

Both could work, but I think sense 1 is actually the better fit because:
- Cancer "coming into existence" is the core meaning
- The "from" just indicates the source/origin

Actually, I'll go with sense 1 because the primary meaning is about cancer coming into existence, and "originate" is a direct synonym. The "from" phrase indicates the source, which is covered by the "originate" synonym.

Hmm, but sense 4 is specifically about "result or issue" which directly maps to "arise from." Let me look at the WordNet hierarchy more carefully.

In WordNet, these senses are organized by verb frames. Sense 4 (arise%2:30:00) is in the "stative" category, while senses 1 and 2 are in "creation/change" categories.

For the specific meaning of "come into being from a cause," sense 1 seems most appropriate with "originate" as a synonym. "Colon cancer originates from multiple hits on cancer suppressor genes" is essentially the same meaning.

I'll go with sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
"I was convinced that what was true of retinoblastoma would be true for all cancers. "It was an audacious claim. But in Baltimore, Dr. Vogelstein, a young molecular biologist at Johns Hopkins Medical School, believed Dr. Knudson was right, and set out to repeat the Cavenee experiment in cells from other cancers. His was one of two research teams in 1984 to report dual chromosome losses for a rare childhood cancer of the kidney called Wilm's tumor. Dr. Vogelstein next turned his attention colon cancer, the second biggest cancer killer in the U.S. after lung cancer. He believed colon cancer might also arise from multiple "hits "on <t>cancer</t> suppressor genes, because it often seems to develop in stages. It often is preceded by the development of polyps in the bowel, which in some cases become increasingly malignant in identifiable stages -- progressing from less severe to deadly -- as though a cascade of genetic damage might be occurring.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word "cancer" appears in the context of medical/scientific discussion about cancer suppressor genes, colon cancer, cell division, and tumors. The sentence reads: "He believed colon cancer might also arise from multiple 'hits' on cancer suppressor genes..."

This is clearly about the disease/cancer as a medical condition - malignant cell growth. This matches sense 1: "any malignant growth or tumor caused by abnormal and uncontrolled cell division."

The other senses relate to astrology/zodiac (senses 2, 3, 4) or a biological genus (sense 5), none of which fit the medical context.