[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
For the treatment of non-small cell lung cancer, the effects of Alimta were compared with those of docetaxel (another anticancer medicine) in one study involving 571 patients with locally advanced or metastatic disease who had received chemotherapy in the past. Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 <t>months</t> in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to disambiguate the word "months" in a medical context about survival time. The two senses are:
1. month%1:28:01:: - one of the twelve divisions of the calendar year (calendar month)
2. month%1:28:00:: - a time unit of approximately 30 days

The context is: "Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone."

Here, "months" refers to a duration of time - approximately 30 days each. It's measuring survival time, not referring to specific calendar months (like January, February, etc.). Even though survival time is roughly 9.3 x 30 days, the meaning is clearly a time unit/duration rather than calendar divisions.

In medical contexts, "survived for X months" always uses the time unit sense.

So the best sense is 2 (month%1:28:00::).

I need to return only a JSON object: {"sense_index": 2}.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the <t>treatment</t> of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content: We need choose sense index for "treatment" in context. The phrase "In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators." This is medical, care provided to improve situation especially medical procedures. Sense 1 is medical treatment. Sense 2 is management/handling, but not primarily medical? Here "treatment of patients" means medical treatment. So index 1. Return JSON only like {"sense_index":1}.

format: unknown

native_finish_reason: stop

provider: Ambient

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of <t>patients</t> with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to perform word sense disambiguation for the target word "patients" in the given context. I need to choose between two senses:
1. patient%1:18:00:: - "a person who requires medical care"
2. patient%1:10:00:: - "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause"

The context is about Alimta, a cancer medicine, and mentions "patients" multiple times. The target surface form "patients" appears in "In the treatment of <t>patients</t> with non-small cell lung cancer..."

This is clearly referring to people receiving medical treatment for a disease. It's the noun meaning "a person who requires medical care", not a grammatical/semantic role used in linguistics.

The first sense is indexed as 1 (patient%1:18:00::). The second is indexed as 2 (patient%1:10:00::).

I need to return only a JSON object: {"sense_index": 1}. The instructions say "Do not answer with a WordNet sense key." and "Return only a JSON object".

So the answer should be exactly:
{"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small <t>cell</t> lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to find which indexed sense the target word "cell" belongs to in the given context.

 The context is about medical studies, cancer treatments, specifically "non-small cell lung cancer".

 In medicine/biology, "cell" refers to the basic structural and functional unit of all organisms. This matches sense 2: "(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals"

 "Non-small cell lung cancer" is a type of lung cancer named based on the appearance of the cancer cells under a microscope. The cancer cells are larger than small cell lung cancer cells. So "cell" here clearly refers to biological cells.

 The answer should be sense_index 2.

 I need to return only a JSON object: {"sense_index": 2}

provider: Venice


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: effective
Target surface form: effective
Context:
Alimta was also compared with gemcitabine (another anticancer medicine), both in combination with cisplatin, in a study involving 1,725 patients who had not received chemotherapy for lung cancer in the past. In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as <t>effective</t> as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel.

Candidate senses:
1. sense_key=effective%3:00:00:: | definition=producing or capable of producing an intended result or having a striking effect; -LewisMumford | synonyms=effectual, efficacious | examples=an air-cooled motor was more effective than a witch's broomstick for rapid long-distance transportation; effective teaching methods
2. sense_key=effective%5:00:00:competent:00 | definition=able to accomplish a purpose; functioning effectively; -G.B.Shaw | synonyms=efficient | examples=people who will do nothing unless they get something out of it for themselves are often highly effective persons...; effective personnel
3. sense_key=effective%5:00:00:efficacious:00 | definition=works well as a means or remedy | examples=an effective reprimand; a lotion that is effective in cases of prickly heat
4. sense_key=effective%5:00:00:operative:00 | definition=exerting force or influence | synonyms=good, in effect, in force | examples=the law is effective immediately; a warranty good for two years
5. sense_key=effective%5:00:00:actual:00 | definition=existing in fact; not theoretical; real | examples=a decline in the effective demand; confused increased equipment and expenditure with the quantity of effective work done
6. sense_key=effective%5:00:00:operational:00 | definition=ready for service | examples=the fort was held by about 100 effective soldiers

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 We need answer JSON with sense_index. Need disambiguate "effective" in sentence: "In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators." This is about medicinal efficacy. Candidates: 1 producing/capable of producing intended result or striking effect (air-cooled motor, teaching methods). synonyms effectual, efficacious. 2 able to accomplish a purpose; functioning effectively; efficient. 3 works well as a means or remedy (an effective reprimand; lotion effective in cases of prickly heat). 4 legal in force. 5 actual. 6 operational. In biomedical context, drug as effective as comparators means producing intended therapeutic result. Sense 1 or 3? Sense 1 definition producing or capable of producing an intended result or having a striking effect. Sense 3 definition works well as a means or remedy. For medicine, "effective" means producing intended result (efficacious). Sense 1 synonyms include efficacious. Sense 3 is possibly a satellite of efficacious with examples reprimand and lotion. The context is treatment; perhaps best sense is sense 1? Need compare. Fine-grained WSD. Let's inspect candidates. Sense 1: adjective effective (producing or capable of producing an intended result or having a striking effect). Examples: air-cooled motor, teaching methods. Sense 3: adjective satellite effective (works well as a means or remedy). Examples reprimand, lotion in prickly heat. This is a more specific sense about remedy/means, closely tied to medical treatment? "works well as a means or remedy" is for treatments/penalties. "Alimta was as effective as comparators in treatment" - the intended result is making patients survive longer. It could fit sense 1 broad intended result. But sense 3 specifically "means or remedy" maybe narrower and more apt for drug. However sense 3 in WordNet is satellite of efficacious? Let's understand WordNet structure. "effective%5:00:00:efficacious:00" means satellite adjective related to efficacious, definition "works well as a means or remedy". So it is a sense of effective used to describe a means/remedy. That's exactly a drug as a remedy. But would "effective" in "as effective as comparators" mean "works well as a means or remedy"? Hmm, "comparators" are other medicines. "Alimta was as effective as the comparators" means it worked equally well as a treatment. Sense 3: "works well as a means or remedy" captures that. Sense 1: producing intended result, could also work, but examples not about remedy; sense 1 is a basic sense "producing or capable of producing an intended result or having a striking effect". Let's examine fine-grained distinction. Many WSD resources might map "effective" in medical efficacy context to sense 1? Let's think semantically. If a drug is effective, it is efficacious (capable of producing intended result) -> sense 1 synonyms include effectual, efficacious. Sense 3 is a refinement of efficacious? Actually in WordNet, "efficacious" is separate adjective core with senses "marked by qualities giving capacity to produce intended result" etc. The satellite effective under efficacious? Wait definitions: sense 1 = effective%3:00:00::; sense 3 = effective%5:00:00:efficacious:00. A satellite of efficacious, derived from "effective" with meaning "works well as a means or remedy". This is a sub-sense of "efficacious". Examples: "an effective reprimand; a lotion that is effective in cases of prickly heat". These are things that work well as a means to an end, especially remedy. Drug is a remedy. So sense 3 appropriate. But "as effective as the comparators" may not strongly emphasize "means or remedy" but comparison of efficacy. Both comparators are also remedies. "Alimta was as effective as the comparators" means Alimta worked equally well as a remedy/medicine. Which sense index to output? We must choose single best. Need decide robustly. Let's explore potential mappings from existing corpora. WordNet sense 1 of "effective" is highly frequent for general "producing intended result". Sense 3 is specific to "works well as means/remedy". In biomedical text "treatment ... effective" may be mapped to sense 1 because the phrase "effective in the treatment" = producing desired result? Some annotated dataset might use sense 3 for "effective treatment". Let's reason from definitions and examples.

Candidate 1 definition: "producing or capable of producing an intended result or having a striking effect". That is the salient sense when describing a medicine that produces intended therapeutic effect. Its synonyms: effectual, efficacious. This sense encompasses efficacy, including medical. Candidate 3 definition: "works well as a means or remedy". This is a more specific sense of effective, perhaps labeled as efficacious. It appears suitable for things used as a means/remedy (reprimand, lotion). "Alimta" is a medicine; treatment is a remedy; thus sense 3 could be better. But sense 1 also includes efficacious and intended result. Which one is more precise? If fine-grained, sense 3 is a satellite sense; choosing it would mean interpreting "effective" as "works well as a remedy". Yet WordNet constructs satellites to refine head adjectives. Effective head sense (3:00:00) = producing intended result. Satellite under "efficacious" (5:00:00:efficacious:00) = works well as a means or remedy. It seems sense 1 might actually be the head sense for efficacious as adjective cluster "effective, effectual, efficacious". Wait in WordNet, the head synset effective%3:00:00 includes effectual, efficacious. The satellite under efficacious includes effective again? Check WordNet: There is adjective synset "efficacious, effectual, effective(a)" as head? Actually WordNet often has cluster where "effective" is similar to "efficacious". The sense key formatting: adjective satellites contain a head_ptr. For effective%5:00:00:efficacious:00, head adjective is efficacious, meaning it's a satellite of "efficacious" cluster. But there is also "effective%3:00:00::" as head. So "effective" has both head and satellite senses. The satellite sense definition might apply when "effective" means "works well as a means or remedy". In the context "Alimta was as effective as comparators", which might correspond to head sense because not explicitly "remedy"? However the topic is medicine.

Instruction: Use context, examples, synonyms. Also do not hedge. The target surface is "effective" in a sentence about a drug's benefit during studies. It is talking about efficacy comparing medicines. The best specific available sense is likely 3 "works well as a means or remedy" because Alimta is a remedy/medicine. But candidate 1 "producing or capable of producing an intended result" also includes intended result of treatment. Let's see examples: Candidate 1 examples include air-cooled motor for transportation, teaching methods. Candidate 3 examples include lotion effective in cases of prickly heat. The latter is much closer to a medicine being effective for a disease. This strongly suggests sense 3 is the best.

However, sense 1 synonyms include "efficacious". Candidate 3 definition literally "works well as a means or remedy". A drug is a remedy. So sense 3 is closer to "producing a therapeutic effect". The word "effective" in drug comparisons is almost always about efficacy; sense 3 is specialized. I think answer index 3.

Let's double-check whether "as effective as comparators" is a general efficacy comparison and perhaps in WSD annotations would choose sense 1 due to its frequency and gloss. But the prompt says fine-grained; use examples. Example of candidate 3 includes "lotion effective in cases of prickly heat" (medical/cosmetic treatment), matching most. Candidate 1 examples are mechanical and teaching. So sense 3 is better due to domain match. Output only JSON.

Need ensure final JSON exact: {"sense_index": 3}. No explanation.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In <t>patients</t> who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to perform Word Sense Disambiguation on the target word "patients" in context. The target lemma is "patient" and surface form is "patients".

Candidate senses:
1. patient%1:18:00:: - a person who requires medical care (example: "the number of emergency patients has grown rapidly")
2. patient%1:10:00:: - semantic role (example: affected/patient role)

Looking at the context, this is a medical/pharmaceutical text about clinical studies of Alimta. The sentence is "In <t>patients</t> who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel."

In this context, "patients" clearly refers to people receiving medical treatment (chemotherapy/Alimta/docetaxel). This is the medical sense. It is NOT a semantic role/linguistics term.

Therefore, sense 1 is the best fit.

provider: Parasail


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the <t>past</t>, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need choose best sense for word "past" in context. Context is medical document: "In patients who had received chemotherapy in the past". Sense options: 1 time that has elapsed/ past times, yesteryear. 2 earlier period in someone's life (especially secret). 3 verb tense. Here "in the past" idiomatic adverb phrase means previously, at some earlier time. Candidate 1 best: the time that has elapsed. Could also arguably sense 2? Candidate 2 is earlier period in someone's life, secret-like, not appropriate for medical treatment history. So answer {"sense_index": 1}.

provider: DeepInfra


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: average
Target surface form: average
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the <t>average</t> survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=average%5:00:02:normal:01 | definition=approximating the statistical norm or average or expected value | synonyms=mean | examples=the average income in New England is below that of the nation; of average height for his age
2. sense_key=average%5:00:00:common:01 | definition=lacking special distinction, rank, or status; commonly encountered | synonyms=ordinary | examples=average people; the ordinary (or common) man in the street
3. sense_key=average%5:00:00:ordinary:00 | definition=lacking exceptional quality or ability | synonyms=fair, mediocre, middling | examples=a novel of average merit; only a fair performance of the sonata
4. sense_key=average%5:00:00:moderate:00 | definition=around the middle of a scale of evaluation | synonyms=intermediate, medium | examples=an orange of average size; intermediate capacity
5. sense_key=average%5:00:03:normal:01 | definition=relating to or constituting the most frequent value in a distribution | synonyms=modal | examples=the modal age at which American novelists reach their peak is 30
6. sense_key=average%5:00:01:normal:01 | definition=relating to or constituting the middle value of an ordered set of values (or the average of the middle two in a set with an even number of values) | synonyms=median | examples=the median value of 17, 20, and 36 is 20; the median income for the year was $15,000

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "average" in context. They want me to choose the single best indexed sense from the 6 candidates provided.

Instructions need to be followed strictly:
1. Choose single best indexed sense
2. Use context, synonyms, and examples
3. Do not answer with WordNet sense key
4. Return only JSON object exactly like {"sense_index": 3}

The target surface form "average" appears in the context: "the average survival time was 8.3 months with Alimta" and "the average survival time was 10.3 months in both groups".

Definition options:
1. approximating the statistical norm or average or expected value; synonyms=mean
2. lacking special distinction; synonyms=ordinary
3. lacking exceptional quality; synonyms=fair, mediocre, middling
4. around middle of scale; synonyms=intermediate, medium
5. relating to most frequent value; synonyms=modal
6. relating to middle value; synonyms=median

In the context, "average survival time" refers to mean survival time - a statistical average computed by summing values and dividing by number of patients. This matches sense 1 (mean). The other usages in the text also refer to statistical averages.

The text: "Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months..." clearly statistical mean.

The target specifically is "the average survival time was 8.3 months with Alimta" - also statistical mean/average.

So sense_index = 1.

Need to return only JSON object exactly like {"sense_index": 3} but with 1. Since instructions say "Return only a JSON object exactly like {"sense_index": 3}", I should output just that line with index value 1. No extra text.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survival
Target surface form: survival
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average <t>survival</t> time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
3. sense_key=survival%1:04:00:: | definition=something that survives

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need answer JSON only. Need choose sense for "survival" in context. Context: medical, survival time, how long patients survived. Candidate senses: 1 state of surviving; remaining alive (endurance). 2 natural process evolution. 3 something that survives. The phrase "average survival time" refers to duration of remaining alive, state of surviving. So sense 1. Need output JSON exactly {"sense_index": 1}. Ensure no extra text.

provider: Cloudflare


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: time
Target surface form: time
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival <t>time</t> was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=time%1:11:00:: | definition=an instance or single occasion for some event | synonyms=clip | examples=this time he succeeded; he called four times
2. sense_key=time%1:28:05:: | definition=a period of time considered as a resource under your control and sufficient to accomplish something | examples=take time to smell the roses; I didn't have time to finish
3. sense_key=time%1:28:00:: | definition=an indefinite period (usually marked by specific attributes or activities) | examples=he waited a long time; the time of year for planting
4. sense_key=time%1:28:06:: | definition=a suitable moment | examples=it is time to go
5. sense_key=time%1:03:00:: | definition=the continuum of experience in which events pass from the future through the present to the past
6. sense_key=time%1:11:01:: | definition=a person's experience on a particular occasion | examples=he had a time holding back the tears; they had a good time together
7. sense_key=time%1:28:03:: | definition=a reading of a point in time as given by a clock | synonyms=clock time | examples=do you know what time it is?; the time is 10 o'clock
8. sense_key=time%1:28:04:: | definition=the fourth coordinate that is required (along with three spatial dimensions) to specify a physical event | synonyms=fourth dimension
9. sense_key=time%1:07:01:: | definition=rhythm as given by division into parts of equal duration | synonyms=meter, metre
10. sense_key=time%1:28:01:: | definition=the period of time a prisoner is imprisoned | synonyms=prison term, sentence | examples=he served a prison term of 15 months; his sentence was 5 to 10 years

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need answer only JSON with sense_index. We need choose among senses 1-10 for target surface "time" in context: "the average survival time was 8.3 months..." The phrase "survival time" means period/duration of time patients survived. It's an indefinite period marked by specific attribute (survival duration). Candidate sense 3: "an indefinite period (usually marked by specific attributes or activities)" examples: "he waited a long time; the time of year for planting". Survival time fits: an indefinite period marked by the duration of survival. Sense 2 is "period of time considered as a resource under your control and sufficient to accomplish something" - no. Sense 10 prison term - no. Sense 5 continuum experience - abstract concept not here. Sense 1 instance/occasion - no. So best = 3. Return JSON.

provider: Moonshot AI


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 <t>months</t> with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need choose sense for "months" in context: a duration of survival time: average of 12.1 months, 9.3 months. These are lengths of time, not specific calendar months. Candidate sense 2 = approximately 30 days as time unit. Sense 1 = calendar months. The target surface is plural months, in measurement of duration. Best indexed sense likely sense 2 (month%1:28:00). Need return JSON exactly {"sense_index": 2}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: compare
Target surface form: compared
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, <t>compared</t> with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=compare%2:31:00:: | definition=examine and note the similarities or differences of | examples=John compared his haircut to his friend's; We compared notes after we had both seen the movie
2. sense_key=compare%2:42:00:: | definition=be comparable | examples=This car does not compare with our line of Mercedes
3. sense_key=compare%2:31:01:: | definition=consider or describe as similar, equal, or analogous | synonyms=liken, equate | examples=We can compare the Han dynasty to the Romans; You cannot equate success in financial matters with greed
4. sense_key=compare%2:32:00:: | definition=to form the comparative or superlative form on an adjective or adverb

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 We need answer as JSON {"sense_index": N}. Need choose sense for target 'compared' in context. Context: phrase "compared with 9.3 months in those receiving cisplatin alone", "compared with 7.9 months with docetaxel." It sets up comparison of survival times. Sense 1: examine and note similarities or differences of. Sense 3: consider or describe as similar, equal, or analogous; synonyms liken, equate. Compared with in numerical/statistical contrast is likely sense 1 (examine/note similarities/differences). "Compared with X" = compared notes. Other uses: compare to (liken), compare with (note differences). In WordNet, compare%2:31:00:: is verb examine and note similarities or differences of. compare%2:31:01:: is liken/equate. The context is statistical comparison of survival times, noting difference. So best index = 1.

Also there is compare%2:32:00 grammar. Not relevant.

Return JSON only.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
In all three studies, the main measure of effectiveness was how long the patients survived. What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 <t>months</t> with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need answer JSON with sense_index. Need choose between 1 and 2 for "months" in context of survival time average 7.9 months. The two senses: 1 calendar month (one of twelve divisions), 2 time unit of approximately 30 days. In medical survival durations, "months" refers to time units of approx 30 days, not calendar months divisions. So sense 2. Return {"sense_index": 2}. Ensure only JSON.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In <t>patients</t> who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need perform fine-grained WSD for lemma patient, surface patients, context is medical study: survival time, chemotherapy. Candidate sense1 = person requiring medical care, sense2 = semantic role patient. Obviously context literally medical patients. Need answer JSON {"sense_index": 1} only. Ensure no extra text.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the <t>past</t>, the average survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We need perform WSD. Target: "past" in clinical context: "In patients who had not received chemotherapy in the past". Need choose among three senses. Let's examine.

1. past as noun: the time that has elapsed; past times, yesteryear; forget the past. This is a general temporal noun meaning previous time. Sense key 1:28:00. Definition "the time that has elapsed". Example: forget the past.

2. past as noun: earlier period in someone's life (especially they have reason to keep secret). Used for biographical hidden past. Not relevant.

3. past as noun: verb tense; past tense. Not grammatical tense context, but temporal reference.

Context: "received chemotherapy in the past". Means previously/in prior time. Which sense 1 fits. Sense 1 definition matches. Sense 2 generally refers to a person's life and can include hidden aspects; but "chemotherapy in the past" is not someone's life history itself, it's just earlier time. Therefore sense 1. Need answer only JSON {"sense_index": 1}. Ensure format exact.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: average
Target surface form: average
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the <t>average</t> survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=average%5:00:02:normal:01 | definition=approximating the statistical norm or average or expected value | synonyms=mean | examples=the average income in New England is below that of the nation; of average height for his age
2. sense_key=average%5:00:00:common:01 | definition=lacking special distinction, rank, or status; commonly encountered | synonyms=ordinary | examples=average people; the ordinary (or common) man in the street
3. sense_key=average%5:00:00:ordinary:00 | definition=lacking exceptional quality or ability | synonyms=fair, mediocre, middling | examples=a novel of average merit; only a fair performance of the sonata
4. sense_key=average%5:00:00:moderate:00 | definition=around the middle of a scale of evaluation | synonyms=intermediate, medium | examples=an orange of average size; intermediate capacity
5. sense_key=average%5:00:03:normal:01 | definition=relating to or constituting the most frequent value in a distribution | synonyms=modal | examples=the modal age at which American novelists reach their peak is 30
6. sense_key=average%5:00:01:normal:01 | definition=relating to or constituting the middle value of an ordered set of values (or the average of the middle two in a set with an even number of values) | synonyms=median | examples=the median value of 17, 20, and 36 is 20; the median income for the year was $15,000

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need choose best WordNet sense index for target "average" in phrase "average survival time". Context describes statistical average of survival time months, mean values (12.1 months etc). WordNet senses: 1=approximating statistical norm/average/expected value; synonyms mean. 5=modal. 6=median. Which specific sense for "average" as adjective in "average survival time"? It likely refers to "average" as mean, sense 1. Need return JSON {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survival
Target surface form: survival
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average <t>survival</t> time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
3. sense_key=survival%1:04:00:: | definition=something that survives

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform word sense disambiguation for the target lemma "survival" in the given context. I need to choose from 3 candidate senses and return a JSON object with the sense index.

Let me analyze the context:
- The text is about a medical study of Alimta (a cancer drug)
- It discusses "survival time" of patients
- It compares how long patients survived on different treatments
- "In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups"
- "patients whose cancer was not affecting squamous cells had longer survival times"

The relevant meaning here is about patients remaining alive for a period of time after treatment.

Looking at the candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
   - This fits the medical context of patient survival time - the state of surviving, remaining alive
   - Noun state/condition

2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
   - This is about evolutionary/natural selection, doesn't fit medical patient survival

3. sense_key=survival%1:04:00:: | definition=something that survives
   - This is about an object/thing that remains, not about living/being alive

The context is clearly about patients remaining alive for X months after treatment. This matches sense 1: "a state of surviving; remaining alive" with synonym "endurance."

I should choose sense_index 1 and format as JSON exactly like {"sense_index": 1}.

provider: Together


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: time
Target surface form: time
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival <t>time</t> was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=time%1:11:00:: | definition=an instance or single occasion for some event | synonyms=clip | examples=this time he succeeded; he called four times
2. sense_key=time%1:28:05:: | definition=a period of time considered as a resource under your control and sufficient to accomplish something | examples=take time to smell the roses; I didn't have time to finish
3. sense_key=time%1:28:00:: | definition=an indefinite period (usually marked by specific attributes or activities) | examples=he waited a long time; the time of year for planting
4. sense_key=time%1:28:06:: | definition=a suitable moment | examples=it is time to go
5. sense_key=time%1:03:00:: | definition=the continuum of experience in which events pass from the future through the present to the past
6. sense_key=time%1:11:01:: | definition=a person's experience on a particular occasion | examples=he had a time holding back the tears; they had a good time together
7. sense_key=time%1:28:03:: | definition=a reading of a point in time as given by a clock | synonyms=clock time | examples=do you know what time it is?; the time is 10 o'clock
8. sense_key=time%1:28:04:: | definition=the fourth coordinate that is required (along with three spatial dimensions) to specify a physical event | synonyms=fourth dimension
9. sense_key=time%1:07:01:: | definition=rhythm as given by division into parts of equal duration | synonyms=meter, metre
10. sense_key=time%1:28:01:: | definition=the period of time a prisoner is imprisoned | synonyms=prison term, sentence | examples=he served a prison term of 15 months; his sentence was 5 to 10 years

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need answer JSON only. Need choose best sense for "time" in sentence: "the average survival time was 10.3 months in both groups." Context about survival time, survival times. It's a period/duration. Candidate senses: 1 instance/occasion (clip). 2 period as resource. 3 indefinite period marked by specific attributes/activities. 4 suitable moment. 5 continuum. 6 experience. 7 clock time. 8 fourth dimension. 9 rhythm. 10 prison term. Survival time means duration of survival, a period of time. Which WordNet sense best? sense 3: an indefinite period (usually marked by specific attributes or activities); examples "he waited a long time; the time of year for planting". Survival time fits: period marked by attribute (survival). Sense 2: a period of time considered as a resource under your control and sufficient to accomplish something; not resource. Sense 1: instance/single occasion; no. Sense 7: clock reading; no. So index 3. Need output JSON exactly {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: month
Target surface form: months
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 <t>months</t> in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=month%1:28:01:: | definition=one of the twelve divisions of the calendar year | synonyms=calendar month | examples=he paid the bill last month
2. sense_key=month%1:28:00:: | definition=a time unit of approximately 30 days | examples=he was given a month to pay the bill

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need choose best indexed sense for target lemma month in form months. Let's analyze. The context is about survival time in months: "average survival time was 10.3 months in both groups." This refers to time units of approximately 30 days. Sense 2: month%1:28:00:: "a time unit of approximately 30 days". Sense 1: calendar month "one of the twelve divisions..." e.g., "last month", names of months. In survival studies, "months" are time units, not calendar months like January. Even though a period could be calendar month, used as duration measure. The surface "10.3 months" strongly suggests approximate 30-day time units, not "tenth month" or division of year. So sense_index 2. Need return JSON exactly {"sense_index": 2}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: group
Target surface form: groups
Context:
What benefit has Alimta shown during the studies? Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both <t>groups</t>. However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator.

Candidate senses:
1. sense_key=group%1:03:00:: | definition=any number of entities (members) considered as a unit | synonyms=grouping
2. sense_key=group%1:27:00:: | definition=(chemistry) two or more atoms bound together as a single unit and forming part of a molecule | synonyms=radical, chemical group
3. sense_key=group%1:09:00:: | definition=a set that is closed, associative, has an identity element and every element has an inverse | synonyms=mathematical group

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to perform Word Sense Disambiguation for the target word "groups" in the given context. Let me analyze the sentence where "groups" appears:

"In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both <t>groups</t>."

Here, "groups" refers to the two sets of patients being compared in the study: those receiving Alimta and those receiving the comparator. This is a collection of entities (patients) considered as a unit.

Let me evaluate the candidate senses:

1. group%1:03:00:: - "any number of entities (members) considered as a unit" - This fits perfectly. The "groups" are sets of patients.
2. group%1:27:00:: - "(chemistry) two or more atoms bound together as a single unit and forming part of a molecule" - This is chemistry-specific and doesn't fit.
3. group%1:09:00:: - "a set that is closed, associative, has an identity element and every element has an inverse" - This is a mathematical group and doesn't fit the context of patient groups in a clinical study.

Sense 1 is clearly the best choice. The answer should be a JSON object with the sense_index. Since sense 1 comes first in the candidate list, the index is 1.

Note: The user says "Return only a JSON object exactly like {"sense_index": 3}." This is just an example format. I need to return {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: however
Target surface form: However
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. <t>However</t>, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=however%4:02:00:: | definition=despite anything to the contrary (usually following a concession) | synonyms=nevertheless, withal, still, yet, all the same, even so | examples=although I'm a little afraid, however I'd like to try it; while we disliked each other, nevertheless we agreed
2. sense_key=however%4:02:04:: | definition=by contrast; on the other hand | examples=the first part was easy; the second, however, took hours
3. sense_key=however%4:02:02:: | definition=to whatever degree or extent | examples=The results, however general, are important; they have begun, however reluctantly, to acknowledge the legitimacy of some of the opposition's concerns
4. sense_key=however%4:02:01:: | definition=in whatever way or manner | examples=Victory, however it was brought about, was sweet; however he did it, it was very clever

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We need disambiguate 'however' in this context. Context: ... Treatment results show Alimta effective/non-small cell lung cancer etc, <t>However</t>, in both studies, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator. This is introducing a contrast relative to previous info. Probably sense 4:02:04 by contrast; on the other hand. Because sentence: The previous data show comparable or equivalent survival (some comparisons). However, in both studies, non-squamous patients had longer survival with Alimta. It is contrasting, by contrast/on the other hand. Sense key 4:02:04. Need output JSON with sense_index: number? The indexes? Candidate senses listed 1,2,3,4. User wants {"sense_index": 3}. Wait the third sense in list is sense_key %4:02:02:: definition to whatever degree..., which is sense_index 3. But the intended correct sense is however%4:02:04:: which is listed as 2? Actually list:
1. %4:02:00:: definition despite...
2. %4:02:04:: definition by contrast...
3. %4:02:02:: to whatever degree
4. %4:02:01:: in whatever way
So sense_index corresponds to the candidate number? Maybe yes. The example says {"sense_index": 3} but they want choose based on normalized WordNet sense numbering? Need be careful: "Return only a JSON object exactly like {"sense_index": 3}". The number should be the index of the chosen sense. The sense_key includes sense lexicographer numbering after %4:02:xx. Could be ambiguous: should we output 2 (candidate order) or 4 (based on WordNet offset)? User says Candidates senses numbered 1-4. The required format uses example index 3. Likely "sense_index" is the candidate number from list. So for correct sense (by contrast), candidate number 2. However the example JSON with 3 is just illustrative; not necessarily the answer. So output {"sense_index": 2}. Need ensure non-hedging. Return only JSON.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: study
Target surface form: studies
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both <t>studies</t>, patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=study%1:04:00:: | definition=a detailed critical inspection | synonyms=survey
2. sense_key=study%1:09:03:: | definition=applying the mind to learning and understanding a subject (especially by reading) | synonyms=work | examples=mastering a second language requires a lot of work; no schools offer graduate study in interior design
3. sense_key=study%1:10:00:: | definition=a written document describing the findings of some individual or group | synonyms=report, written report | examples=this accords with the recent study by Hill and Dale
4. sense_key=study%1:09:04:: | definition=a state of deep mental absorption | examples=she is in a deep study
5. sense_key=study%1:06:00:: | definition=a room used for reading and writing and studying | examples=he knocked lightly on the closed door of the study
6. sense_key=study%1:09:02:: | definition=a branch of knowledge | synonyms=discipline, subject, subject area, subject field, field, field of study | examples=in what discipline is his doctorate?; teachers should be well trained in their subject
7. sense_key=study%1:06:01:: | definition=preliminary drawing for later elaboration | synonyms=sketch | examples=he made several studies before starting to paint
8. sense_key=study%1:09:01:: | definition=attentive consideration and meditation | synonyms=cogitation | examples=after much cogitation he rejected the offer
9. sense_key=study%1:18:00:: | definition=someone who memorizes quickly and easily (as the lines for a part in a play) | examples=he is a quick study
10. sense_key=study%1:10:01:: | definition=a composition intended to develop one aspect of the performer's technique | examples=a study in spiccato bowing

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 We need perform WSD for target lemma study surface form studies. Context is a medical/pharma paragraph. "However, in both studies, patients whose cancer was not affecting squamous cells had longer survival times..." We need choose one of 10 indexed senses. Let's map the candidate sense_key list to indices. They are listed 1-10. The target usage: "studies" referring to clinical trials/research investigations? The senses: 1: detailed critical inspection, survey. 3: written document describing findings; examples "this accords with the recent study by Hill and Dale". But here "in both studies" refers maybe to clinical trials, i.e., pieces of research (reports). Which sense best? In WordNet, study%1:10:00 is "a written document describing the findings of some individual or group" syn report written report. However clinical trials could be "study%1:04:00"? Let's examine. sense 1 definition detailed critical inspection, survey. Example? Not given. A clinical trial/study is an investigation/research. WordNet includes "survey" maybe. But the phrase "recent study by Hill and Dale" example matches written document. The context: "in both studies, patients ..." In medical context, "studies" could refer to research studies (pieces of research) whose findings are described. But the sentence says "in both studies, patients... had longer survival times". That references the research investigations as contexts/environments, not solely the written documents. Need decide between sense 1 and 3.

Candidate sense 1 synonyms: survey. Could be "a detailed critical inspection". That generally maps to "study" as a careful examination/investigation. Candidate sense 3 synonyms report, written report; examples: "this accords with the recent study by Hill and Dale". Here studies are perhaps clinical studies, research projects, synonymous with "trials". WordNet sense 1:04:00 maybe "a detailed critical inspection" includes "survey". It can refer to an investigation. In WSD, sense 1 likely covers "a study was conducted". Sense 3 covers "according to a study by X" (document). The context: "In both studies" with survival times measured; these are the clinical trials described. The studies are investigations; not written documents. Therefore best sense is likely sense 1.

But let's check WordNet index semantics. study%1:04:00 senses under noun Tops? Actually study is noun:1:04? The first sense is "a detailed critical inspection." (also survey). This is an act; survey. Sense 1:10:00 written document report. The target "studies" here described in context: Alimta increased survival. Patients receiving... In the treatment... etc. "However, in both studies..." It refers back to two studies/trials: one in malignant pleural mesothelioma, one in non-small cell lung cancer? Actually paragraphs describe clinical trials/studies. It says "However, in both studies, patients whose cancer was not affecting squamous cells..." This definitely refers to the clinical studies/research investigations. So choose sense_index: 1.

We need output JSON exactly {"sense_index": n}. Ensure no extra text.

Let's confirm no other sense more apt. Sense 8: attentive consideration and meditation. No. Sense 9: someone quick study. No. Sense 6: branch of knowledge. No. Sense 2: applying mind to learning. No. So between 1 and 3. The word "studies" can denote research papers, but context is "patients in both studies". More likely investigation. So answer 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, <t>patients</t> whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need perform WSD for lemma patient surface patients in context. We need choose between two candidate senses: patient%1:18:00:: (person requiring medical care) and patient%1:10:00:: (semantic role). Context: drug Alimta survival time of patients with malignant pleural mesothelioma. It is clearly human patients receiving treatment, people who require medical care. So sense 1. Return JSON {"sense_index":1}. Ensure no extra text.

provider: Novita


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, patients whose <t>cancer</t> was not affecting squamous cells had longer survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need respond with JSON only. Need choose sense index for "cancer" in given medical context. The context: patients whose cancer was not affecting squamous cells ... patients whose cancer was affecting squamous cells. That's malignant disease sense 1. Need output {"sense_index": 1}. No extra text.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not <t>affecting</t> squamous cells had longer survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We need choose single best indexed sense for target lemma affect surface form affecting in context. Need disambiguate. Context: medical oncology, Alimta, patients whose cancer was not affecting squamous cells had longer survival times; patients whose cancer was affecting squamous cells had shorter survival times. Meaning: cancer affecting squamous cells = cancer involves/has an effect on squamous cells? In medicine, "affecting" often means involved, present in, involving. WordNet sense 1 "have an effect upon" includes impact. Sense 2 "act physically on; have an effect upon" more concrete physically. Sense 3 "connect closely and often incriminatingly" synonyms involve, regard, example ruling affects business. Sense 2 possibly most direct because cancer (disease) physically acting on squamous cells. But the phrase "cancer was affecting squamous cells" could mean cancer is affecting/having an effect on/harming squamous cells.

Let's evaluate candidates:
1 have an effect upon | synonyms impact, bear upon, bear on, touch on, touch | examples Will the new rules affect me? (generic)
2 act physically on; have an effect upon | no synonyms | examples the medicine affects my heart rate (physical/chemical effect on body/cells)
3 connect closely and often incriminatingly | synonyms involve, regard | examples This new ruling affects your business (relate to concern)
4 deception no
5 emotional/cognitive impact: examples This child impressed me... no.

We need choose best indexed sense. Fine-grained WordNet sense idx. Context: cancer cells tissue. "affecting squamous cells" means acting physically on them? Hmm. Could also be "involving" (cancer affecting squamous cells involves them). In medical literature, "affecting" X = involving X, i.e., located in or involving tissue/organ. WordNet sense 1 generic "have an effect upon" also fits. Which is better? Let's inspect WordNet hierarchy. The index 2 likely a hyponym of 1? Actually affect%2:30:00 and affect%2:29:00 under verb? WordNet sense structures: affect v senses: 1. have an effect upon (2:30:00); 2. act physically on; have an effect upon (2:29:00); 3. connect closely... (2:42:00); 4. make believe...; 5. have emotional... ? Wait verbs lexicographer files codes: 29 body actions? 42 is stative? 30 is verb.contact? 37 verb.emotion? Hmm. Let's consider examples.

Sentence "patients whose cancer was affecting squamous cells" - not active agent but passive voice cancer affecting cells. In medicine, "tumour affecting the lung" means tumour located in/involving the lung. WordNet 3 "connect closely and often incriminatingly" synonyms involve, regard. Could be more like "affects" = concerns/involves? Example "This new ruling affects your business" = concerns. Medical text often uses "patients with cancer affecting the skin" to mean cancer involving the skin. However definition "connect closely and often incriminatingly" seems not right connotation in medicine. The synonym "involve" is exactly medical usage. The relation is: if a disease affects an organ, it involves that organ? Let's think.

In WSD, glosses are schematic. The task likely is to differentiate senses. Here target word "affecting" in context "cancer was not affecting squamous cells". The intended sense probably sense 2: act physically on; have an effect upon (medicine affects my heart rate). Because it describes a pathological process acting on cells. Yet sense 1 generic "have an effect upon" is also applicable, but sense 2 is more specific (physical action). Fine-grained WSD prefers more specific if context. The sentence concerns cancer biologically affecting cells. Examples: "the medicine affects my heart rate". Heart rate vs squamous cells. So sense 2.

Is there any chance they want sense 3? It includes involve. The context sentence: "patients whose cancer was not affecting squamous cells had longer survival times if they received Alimta than if they received comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times." They are classifying cancers by histological type: squamous vs non-squamous. Actually non-small cell lung cancer histology: squamous and non-squamous. So "cancer affecting squamous cells" means squamous cell carcinoma, i.e., cancer of squamous cells. Does "affecting" here mean "involving" the squamous cells? Yes. However, in drug labels, phrase "cancer affecting squamous cells" is a weird way to say "squamous cell cancer" maybe. But they literally mean the cancer affects (impacts/involves) squamous cells. Which WordNet sense? Sense 2 generic physical, or sense 3 involve.

Let's see definitions more precisely. Because WordNet includes affect%2:29:00:: as "act physically on; have an effect upon" with one example. Gloss exactly includes "act physically on" and "have an effect upon". In context, cancer acting physically on squamous cells (growing in them) is plausible. Sense 3 "connect closely and often incriminatingly" is more about legal/financial personal relevance. Medical texts do say "affect" as "to attack or infect, as a disease" e.g., "polio affects children". But WordNet doesn't have a sense specifically 'disease affects part of body' actually maybe sense 2? "the medicine affects my heart rate". It may be the key: the verb affect meaning to produce a change in something, to influence. That is sense 1 maybe. Sense 2 might be a hyponym for physical effect. Since cells are physical entities, sense 2.

Which indexed sense is "single best"? Need output JSON with sense_index. Could be 2 or 1. Let's decide.

Consider candidate examples mapping:
- Sense 1 example "Will the new rules affect me?" abstract rules affecting person.
- Sense 2 example "the medicine affects my heart rate" substance/chemical/physical agent has effect on physiological process/cells.
- Sense 3 example "This new ruling affects your business" concerns/involves entity.

In "cancer affecting squamous cells", the cancer is not a medicine but disease. It produces physical effect on cells. So sense 2's domain fits. It is more specific than sense 1. So choose 2.

Need output exactly {"sense_index": 2} with no extra text. Ensure valid JSON only.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: long
Target surface form: longer
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had <t>longer</t> survival times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=long%3:00:02:: | definition=primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified | examples=a long life; a long boring speech
2. sense_key=long%3:00:01:: | definition=primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified | examples=a long road; a long distance
3. sense_key=long%5:00:00:tall:00 | definition=of relatively great height; - Sherwood Anderson | examples=a race of long gaunt men; looked out the long French windows
4. sense_key=long%3:00:00:: | definition=good at remembering | synonyms=retentive, recollective, tenacious | examples=a retentive mind; tenacious memory
5. sense_key=long%3:00:05:: | definition=holding securities or commodities in expectation of a rise in prices | examples=is long on coffee; a long position in gold
6. sense_key=long%3:00:04:: | definition=(of speech sounds or syllables) of relatively long duration | examples=the English vowel sounds in `bate', `beat', `bite', `boat', `boot' are long
7. sense_key=long%5:00:00:unsound:00 | definition=involving substantial risk | examples=long odds
8. sense_key=long%5:00:00:provident:00 | definition=planning prudently for the future | synonyms=farseeing, farsighted, foresighted, foresightful, prospicient, longsighted | examples=large goals that required farsighted policies; took a long view of the geopolitical issues
9. sense_key=long%5:00:00:abundant:00 | definition=having or being more than normal or necessary: | examples=long on brains; in long supply

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need choose best WordNet sense for "longer" (target surface comparative of long). Context: patients had longer survival times if received Alimta than comparator. Survival times are temporal durations. Candidate lists: sense 1 primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified. Examples a long life; a long boring speech. That's temporal/extension in duration. Sense 2 is spatial. Sense 9 abundant/having more than normal but examples "long on brains". This context is duration, not abundantly supplied. Comparative longer fits sense 1. Need output JSON object exactly like {"sense_index": 3}. Since target sense is index 1? The candidate senses numbered 1-9 in the list. We need use "sense_index": 1. Ensure no extra text.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: survival
Target surface form: survival
Context:
Alimta increased the survival time of patients with malignant pleural mesothelioma. Patients receiving Alimta and cisplatin survived for an average of 12.1 months, compared with 9.3 months in those receiving cisplatin alone. In the treatment of patients with non-small cell lung cancer, Alimta was as effective as the comparators. In patients who had received chemotherapy in the past, the average survival time was 8.3 months with Alimta, compared with 7.9 months with docetaxel. In patients who had not received chemotherapy in the past, the average survival time was 10.3 months in both groups. However, in both studies, patients whose cancer was not affecting squamous cells had longer <t>survival</t> times if they received Alimta than if they received the comparator. In contrast, patients whose cancer was affecting squamous cells had shorter survival times if they received Alimta.

Candidate senses:
1. sense_key=survival%1:26:00:: | definition=a state of surviving; remaining alive | synonyms=endurance
2. sense_key=survival%1:22:00:: | definition=a natural process resulting in the evolution of organisms best adapted to the environment | synonyms=survival of the fittest, natural selection, selection
3. sense_key=survival%1:04:00:: | definition=something that survives

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We need determine best sense. user gave context with target word "survival" in sentence about survival times in cancer patients receiving Alimta. Candidate senses: 1 survival%1:26:00:: state of surviving; remaining alive; synonyms endurance. 2 natural process selection. 3 something that survives. Here "survival times" means duration patients remain alive. Schematic gloss sense 1 a state of surviving; remaining alive fits. Answer JSON only {"sense_index": 1}. Just return final.