[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the target word "given" (lemma "give") in the provided context.

 Context analysis:
 The text is about medical usage of a drug called Alimta. The specific sentence containing the target word is: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be <t>given</t> before or after the cisplatin dose."

 The target word "given" here refers to administering medicine/drugs to patients. It's about transferring possession of something concrete (medicine, fluids) to somebody (the patient) in a medical context.

 Looking at the candidate senses:

 1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
 - This is about causing someone to have something, but the examples suggest causing conditions (black eye, cold), not administering medication.

 2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
 - This is about being the source of something abstract like trouble or information.

 3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
 - This is a general transfer of possession. While medicine could fit here, there's a more specific sense for medicine.

 4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
 - Not relevant here.

 5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
 - About conveying abstract things like compliments.

 6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
 - Not relevant.

 7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
 - Not relevant.

 8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
 - This is about gifting, not medical administration.

 9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
 - About causing outcomes.

 10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
 - Not relevant.

 11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
 - This is about producing/supplying, not administering to a patient.

 12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
 - About transmitting knowledge.

 13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
 - Not relevant.

 14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
 - About temporary custody.

 15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
 - Not relevant.

 16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
 - Not relevant.

 17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
 - This is about physically handing something over.

 18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
 - Not relevant.

 19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
 - This is specifically about giving medicine/drugs. The example "I gave him the drug" matches perfectly with the context of giving anti-emetic medicine and fluids (intravenously or orally) to a patient.

 20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
 - This is about physical actions like first aid or punching. While medicine could be physical, sense 19 is more specific.

 21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
 - Not relevant.

 22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
 - Not relevant.

 23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
 - Not relevant.

 24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
 - This is specifically about food. While fluids could be considered similar, medicine is not food.

 25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
 - Not relevant.

 26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
 - Not relevant.

 27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
 - Not relevant.

 28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
 - Not relevant.

 29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
 - Not relevant.

 30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
 - Not relevant.

 31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
 - Not relevant.

 32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
 - Not relevant.

 33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
 - Not relevant.

 34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
 - Not relevant.

 35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
 - Not relevant.

 36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
 - Not relevant.

 37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
 - Not relevant.

 38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
 - Not relevant.

 39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
 - Not relevant.

 40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
 - Not relevant.

 41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
 - Not relevant.

 42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
 - Not relevant.

 43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
 - Not relevant.

 44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
 - Not relevant.

 The best match is clearly sense 19: "give (as medicine)" with the example "I gave him the drug". The context is explicitly about giving medicine (anti-emetic medicine and fluids) to patients in a medical setting.

 The index for this sense in the list is 19.

 Wait, I need to check the indexing. The user lists them as:
 1. sense_key=give%2:40:03::
 2. sense_key=give%2:40:05::
 ...
 19. sense_key=give%2:40:13::

 So the index is 19.

 Let me double-check if any other sense could be better.
 Sense 3: "transfer possession of something concrete or abstract to somebody" - This is a hypernym of sense 19. Sense 19 is more specific and therefore better for WSD when available.
 Sense 20: "give or convey physically" - This could apply to giving first aid or medicine, but sense 19 is specifically for medicine.
 Sense 24: "give food to" - Fluids might be close to food, but anti-emetic medicine is definitely not food, and the context is clearly medical administration.

 Therefore, sense 19 is the correct choice.

 The output should be: {"sense_index": 19}


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: before
Target surface form: before
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given <t>before</t> or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=before%4:02:03:: | definition=earlier in time; previously | synonyms=earlier | examples=I had known her before; as I said before
2. sense_key=before%4:02:01:: | definition=at or in the front | synonyms=ahead, in front | examples=I see the lights of a town ahead; the road ahead is foggy

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "before" in the given context.

 Context analysis:
 The sentence is: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose."

 Here, "before" is used in a temporal sense - referring to time. The medicines should be given earlier in time than the cisplatin dose, or after it.

 Candidate sense 1: "earlier in time; previously" - This fits the temporal meaning. The anti-emetic and fluids should be given earlier in time relative to the cisplatin dose.

 Candidate sense 2: "at or in the front" - This is a spatial meaning (ahead, in front). This doesn't fit because we're talking about the timing of medication administration, not physical position.

 The context clearly involves a temporal sequence: giving medication at a time point that precedes the cisplatin dose.

 Therefore, sense 1 is the correct choice.

 The sense key for sense 1 is before%4:02:03::, which corresponds to sense_index 1 in the list provided.

 I need to return: {"sense_index": 1}

format: unknown

native_finish_reason: stop

provider: StreamLake

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: after
Target surface form: after
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=after%4:02:01:: | definition=happening at a time subsequent to a reference time | synonyms=subsequently, later, afterwards, afterward, later on | examples=he apologized subsequently; he's going to the store but he'll be back here later
2. sense_key=after%4:02:00:: | definition=behind or in the rear | examples=and Jill came tumbling after

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "after" in a specific context.

Context analysis:
The sentence is: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or <t>after</t> the cisplatin dose."

Here, "after" refers to a temporal relationship - the administration of medicines/fluids should happen subsequent to (in time) the cisplatin dose, as opposed to before it.

Candidate sense analysis:
1. sense_key=after%4:02:01:: | definition=happening at a time subsequent to a reference time | synonyms=subsequently, later, afterwards, afterward, later on | examples=he apologized subsequently; he's going to the store but he'll be back here later
- This sense is temporal, indicating time sequence
- Synonyms like "subsequently", "later", "afterwards" all indicate temporal succession
- Fits the medical context where treatments are sequenced in time

2. sense_key=after%4:02:00:: | definition=behind or in the rear | examples=and Jill came tumbling after
- This sense is spatial, indicating physical position (behind)
- Example "Jill came tumbling after" refers to physical movement/position
- Does not fit the temporal context of drug administration timing

The context clearly involves timing of medical treatments (before or after the cisplatin dose), so sense 1 is the correct choice.

The user wants the output as: {"sense_index": 1} (referring to the first indexed sense in the list provided)

Wait, looking carefully at the candidate senses:
- The first one listed is sense_key=after%4:02:01::
- The second one is sense_key=after%4:02:00::

So sense_index should be 1 for the first one (temporal) or 2 for the second one (spatial).

Given the context is temporal, the answer is sense_index: 1.

The user explicitly says "Return only a JSON object exactly like {"sense_index": 3}" - so I need to return {"sense_index": 1} or {"sense_index": 2} depending on which one is correct.

Since the temporal sense is listed first (index 1), the answer is {"sense_index": 1}.

Double-checking the WordNet sense keys:
- after%4:02:01:: is indeed the temporal sense (subsequently)
- after%4:02:00:: is the spatial sense (behind)

Yes, in WordNet:
- after%4:02:00:: = behind or in the rear
- after%4:02:01:: = happening at a time subsequent to a reference time

The context is clearly temporal (before or after the dose - temporal sequence), so index 1 is correct.

Final check: The user said "Choose the single best indexed sense" and the candidates are numbered 1 and 2. So I should return {"sense_index": 1}.

provider: Moonshot AI


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the word "dose" in the given context.

 Context analysis:
 The text is about Alimta (a chemotherapy drug) and how it's administered. The specific sentence containing the target word is: "When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin <t>dose</t>."

 The context is clearly medical/pharmaceutical. It's talking about administering cisplatin (another chemotherapy drug) and giving other medicines before or after the cisplatin "dose".

 Candidate sense analysis:

 1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
    - This refers to a physical portion of medicine (the artifact/substance itself)
    - "taken" suggests oral administration or consumption by the patient
    - In the context, cisplatin is given intravenously (based on earlier context about Alimta being given as intravenous infusion), so "taken" might not fit perfectly, but "portion of medicine" could work

 2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
    - This refers to the quantity/amount of substance
    - "taken in or absorbed" - again suggests entering the body
    - This is more abstract than sense 1 (quantity vs physical portion)
    - In medical contexts, "dose" often refers to the amount/quantity administered

 3. sense_key=dose%1:26:00:: | definition=a communicable infection... (venereal disease)
    - This is clearly wrong. Context is about chemotherapy drugs, not STDs.

 4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide (LSD)
    - This is slang for LSD. Context is about cisplatin (a platinum-based chemotherapy drug), not LSD.

 So it's between sense 1 and sense 2.

 Sense 1 (dose%1:06:00::): This is under noun.artifact (1:06), referring to a physical thing - "a measured portion of medicine" - the actual pills or liquid volume.

 Sense 2 (dose%1:23:00::): This is under noun.quantity (1:23), referring to "the quantity of an active agent" - the amount, measurement.

 In the context: "before or after the cisplatin dose" - here, "dose" refers to the administration/quantity of cisplatin given to the patient. In medical contexts, especially with intravenous drugs like cisplatin, "dose" typically refers to the quantity administered (e.g., 75 mg/m²), not the physical substance itself.

 However, looking at the glosses:
 - Sense 1: "a measured portion of medicine taken at any one time"
 - Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"

 Both mention "taken" which might imply oral, but sense 2 mentions "substance or radiation" which is broader and includes IV drugs.

 Actually, looking carefully at WordNet:
 - dose%1:06:00:: is "a measured portion of medicine taken at any one time" - this is the physical form (the pills, the injection fluid)
 - dose%1:23:00:: is "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time" - this is the measurement/amount

 In the sentence: "before or after the cisplatin dose" - this is referring to the administration event or the amount given. In medical writing, when we say "the cisplatin dose", we usually mean the quantity/amount of cisplatin being administered.

 But let's look at the examples in the context:
 - "The recommended dose of Alimta is 500 mg per square metre..." - here dose clearly means quantity/measurement (500 mg...)
 - "Treatment should be delayed or discontinued, or the dose reduced..." - here "dose reduced" clearly refers to reducing the quantity/amount

 So in the target sentence "before or after the cisplatin dose", it's consistent with this usage - referring to the quantity/administration of cisplatin.

 Between sense 1 and 2:
 Sense 2 seems more appropriate because:
 1. It emphasizes "quantity" which matches the earlier mention of "500 mg per square metre"
 2. It includes "substance" which covers the medicine
 3. Sense 1 emphasizes "portion" which is more concrete/physical

 However, looking at actual WordNet usage:
 - dose%1:06:00:: (artifact) - examples might include "take your dose"
 - dose%1:23:00:: (quantity) - examples might include "a dose of radiation"

 In chemotherapy contexts, "dose" is definitely a quantity (noun.quantity).

 Also, looking at the synonyms: both have "dosage" as a synonym.

 Actually, checking WordNet structure:
 - dose%1:06:00:: is the first sense (artifact)
 - dose%1:23:00:: is the second sense (quantity)

 In many WSD datasets, for "dose of medicine" contexts, sense 2 (quantity) is often the correct one when referring to the amount, while sense 1 might be used when referring to the physical pills.

 But in the phrase "cisplatin dose", it's referring to the administration of the specific quantity of cisplatin.

 Let me reconsider the glosses carefully:
 Sense 1: "a measured portion of medicine taken at any one time"
 Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time"

 The key difference is "portion" (physical) vs "quantity" (abstract measurement).

 In "before or after the cisplatin dose", we are talking about the time relative to when the cisplatin is administered. This refers to the event of giving the quantity of drug.

 However, looking at the broader context:
 - "The recommended dose... is 500 mg" - clearly quantity (sense 2)
 - "the dose reduced" - clearly quantity (sense 2)
 - "the cisplatin dose" - should be consistent with the above

 Therefore, sense 2 (dose%1:23:00::) is the best choice.

 Wait, I should verify the sense indices. The user lists:
 1. sense_key=dose%1:06:00::
 2. sense_key=dose%1:23:00::
 3. sense_key=dose%1:26:00::
 4. sense_key=dose%1:06:01::

 So index 2 corresponds to dose%1:23:00::.

 But let me double-check if there's any ambiguity with sense 1. Could "cisplatin dose" refer to the physical injection? The text says "given before or after the cisplatin dose". If it were the physical portion, it might be "given before or after the cisplatin" (the drug itself). But "dose" here emphasizes the measured amount being administered.

 Also, cisplatin is given intravenously, not "taken" orally (though WordNet glosses use "taken" loosely sometimes).

 Actually, looking at WordNet examples for these senses (if I recall):
 - For dose%1:06:00:: (artifact): "he took his dose of medicine"
 - For dose%1:23:00:: (quantity): "a dose of penicillin", "radiation dose"

 In medical contexts involving specific drugs like cisplatin, and especially when discussing timing relative to administration, sense 2 (quantity) is standard.

 Also, the fact that earlier in the text it mentions "The recommended dose... 500 mg" which is clearly a quantity/measurement, establishes that "dose" in this text is being used in the quantity sense.

 Therefore, the answer should be sense_index: 2.

 Wait, I need to be careful. The user asks for the "single best indexed sense" and to return {"sense_index": 3} (as an example format).

 So I should return {"sense_index": 2}.

 But let me reconsider one more time. Is there any chance sense 1 is correct?
 "before or after the cisplatin dose" - could this mean before or after the physical portion of cisplatin is given? Yes, but the distinction in WordNet is subtle. However, given that:
 1. The text explicitly mentions "500 mg" as a dose earlier
 2. The text mentions "the dose reduced" - reduction applies to quantity, not the physical artifact (though you could reduce the portion size)
 3. Cisplatin is a substance/active agent

 Sense 2 specifically mentions "active agent (substance or radiation)" which fits cisplatin perfectly (it's a chemical substance). Sense 1 mentions "medicine" which is broader but implies the physical form.

 In WordNet, sense 2 (quantity) is the hypernym of sense 1? No, actually they are co-hyponyms or related differently. Let me think... actually in WordNet, dosage is the quantity, and dose can be either the quantity or the physical thing.

 Actually, looking at the hierarchy:
 - dose%1:06:00:: is under artifact -> instrumentality -> container (roughly, as a portion)
 - dose%1:23:00:: is under quantity -> measure -> indefinite quantity

 Given the context is about calculating "500 mg per square metre" and "dose reduced", this is clearly the quantity sense.

 Final decision: sense_index 2.

provider: ModelRun


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: Treatment
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. <t>Treatment</t> should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "treatment" in the given context.

 Context analysis:
 - The text is about a medical drug called Alimta (used for anticancer chemotherapy)
 - It describes dosing, administration, and management of the drug
 - The specific sentence containing the target word: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
 - This is clearly referring to medical treatment/care provided to patients

 Candidate sense analysis:
 1. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
    - This fits perfectly. The context is about medical care (Alimta chemotherapy), delaying or discontinuing the medical procedure based on patient condition.

 2. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
    - While "management" could loosely fit, the specific context is medical care, not general management or handling. The examples show non-medical contexts (prisoners, sewage).

 3. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture
    - This is about artistic treatment, clearly not relevant to the medical context.

 4. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse
    - This is about verbal/written discussion of a topic, not medical care.

 The context is clearly medical: "anticancer chemotherapy", "patients", "blood counts", "side effects", "dose". The word "treatment" here refers to the medical care being provided (the chemotherapy treatment with Alimta).

 Therefore, sense 1 is the correct choice.

 The user wants the output as: {"sense_index": 1}

provider: AtlasCloud


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: delay
Target surface form: delayed
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be <t>delayed</t> or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=delay%2:30:00:: | definition=cause to be slowed down or delayed | synonyms=detain, hold up | examples=Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform
2. sense_key=delay%2:42:00:: | definition=act later than planned, scheduled, or required | examples=Don't delay your application to graduate school or else it won't be considered
3. sense_key=delay%2:30:01:: | definition=stop or halt | synonyms=stay, detain | examples=Please stay the bloodshed!
4. sense_key=delay%2:30:05:: | definition=slow the growth or development of | synonyms=check, retard | examples=The brain damage will retard the child's language development

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to perform Word Sense Disambiguation for the word "delayed" in the given context.

 Context analysis:
 - The text is about medical treatment with Alimta (a chemotherapy drug)
 - The specific sentence: "Treatment should be <t>delayed</t> or discontinued, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."
 - This means that the administration of treatment should be postponed or put off until later (or stopped entirely) if certain conditions are met.

 Candidate sense analysis:

 1. sense_key=delay%2:30:00:: | definition=cause to be slowed down or delayed | synonyms=detain, hold up
    - This is a transitive sense where someone causes something to be delayed.
    - Example: "Traffic was delayed by the bad weather"
    - In our context, treatment is being delayed (passive voice), but the meaning is about postponing the treatment, not necessarily "causing to be slowed down" in the sense of hindering progress. However, this could fit if we think of it as causing the treatment schedule to be pushed back.

 2. sense_key=delay%2:42:00:: | definition=act later than planned, scheduled, or required
    - This seems to be intransitive or about the act of delaying.
    - Example: "Don't delay your application..."
    - This sense seems to fit well with the idea of postponing treatment - acting later than the scheduled time.

 3. sense_key=delay%2:30:01:: | definition=stop or halt | synonyms=stay, detain
    - Example: "Please stay the bloodshed!"
    - This seems archaic or specific to certain contexts. "Stay" here means to stop. While "discontinued" in the context means to stop, "delayed" doesn't mean permanently stopped, it means postponed. So this is not the right sense.

 4. sense_key=delay%2:30:05:: | definition=slow the growth or development of | synonyms=check, retard
    - Example: "The brain damage will retard the child's language development"
    - This is about slowing development/growth, not postponing a scheduled medical treatment.

 Now comparing sense 1 and sense 2:

 Sense 1 (delay%2:30:00::): "cause to be slowed down or delayed" - This is the transitive verb meaning to make something happen later than expected. The examples show "Traffic was delayed" (passive) and "she delayed the work" (active).

 Sense 2 (delay%2:42:00::): "act later than planned, scheduled, or required" - This seems to be the intransitive sense or the sense where the subject is the one doing the delaying in terms of timing.

 Looking at the context: "Treatment should be delayed" - this is passive voice. The treatment is the object being acted upon. It should be made to happen later than scheduled.

 In WordNet:
 - delay%2:30:00:: is the verb "delay" meaning to cause a delay, detain, hold up.
 - delay%2:42:00:: is the verb "delay" meaning to act later than planned.

 Actually, looking at WordNet structure:
 - delay%2:30:00:: is usually the transitive sense: "cause to be slowed down or delayed"
 - delay%2:42:00:: is usually the intransitive sense: "act later than planned, scheduled, or required"

 In the sentence "Treatment should be delayed", we have a passive construction. The treatment is being caused to be postponed. This aligns with sense 1 (transitive, passive).

 However, let's look more carefully at the glosses and examples:

 Sense 1: "cause to be slowed down or delayed" - synonyms: detain, hold up. Examples: "Traffic was delayed by the bad weather; she delayed the work that she didn't want to perform"
 - This fits "Treatment should be delayed" - the treatment should be caused to be delayed/postponed.

 Sense 2: "act later than planned, scheduled, or required" - Example: "Don't delay your application..."
 - This is about the subject acting later. If we said "The doctor should delay", this might fit, but "Treatment should be delayed" puts treatment as the object being postponed, not the subject acting later.

 Actually, looking at the example for sense 2: "Don't delay your application" - here "delay" is transitive too. So both can be transitive.

 Let me reconsider the WordNet senses properly:

 In WordNet 3.0/3.1:
 - delay (v) 1: cause to be slowed down or delayed; "Traffic was delayed by the bad weather"; "she delayed the work that she didn't want to perform"
 - delay (v) 2: act later than planned, scheduled, or required; "Don't delay your application to graduate school or else it won't be considered"
 - delay (v) 3: stop or halt; "Please stay the bloodshed!"
 - delay (v) 4: slow the growth or development of; "The brain damage will retard the child's language development"

 Sense 2's example "Don't delay your application" shows it can be used transitively too. But the gloss "act later than planned..." suggests the core meaning is about the timing of the action.

 However, in medical contexts, when we say "treatment was delayed", we mean it was postponed to a later time. This is closer to sense 1 (causing it to be later) or sense 2 (acting later).

 But sense 1 focuses on "slowed down or delayed" - the "delayed" in the gloss is circular. The key is "cause to be slowed down" vs "act later than planned".

 In "Treatment should be delayed", the treatment is the thing being scheduled. If it's delayed, it's being caused to occur at a later time than originally planned.

 Sense 1 seems to be the best fit because:
 1. It's the most common sense for "delay" when referring to postponing events/procedures
 2. The passive construction "be delayed" matches the passive example in sense 1 ("Traffic was delayed")
 3. Sense 2's gloss "act later than planned" focuses on the actor's behavior, whereas here the treatment itself is being postponed

 Wait, looking at sense 2 again: "act later than planned, scheduled, or required". If treatment is delayed, it is acting (occurring) later than planned. But treatment doesn't "act", it "is administered".

 Actually, looking carefully at the examples:
 - Sense 1: "Traffic was delayed" - traffic is not an actor, it's the thing being affected. This is parallel to "Treatment should be delayed".
 - Sense 2: "Don't delay your application" - here the person is delaying the application (postponing submission), or the application is being made to occur later.

 But the key distinction in WordNet is:
 - Sense 1 (delay%2:30:00::) belongs to the "change" verb class (causing a change in timing)
 - Sense 2 (delay%2:42:00::) belongs to... actually I need to check the lexicographer files.

 delay%2:30:00:: - verb.change (cause to change)
 delay%2:42:00:: - verb.social? No, let me check.

 Actually, looking at standard WordNet:
 - delay%2:30:00:: is in verb.change (cause to be slowed down)
 - delay%2:42:00:: is in verb.social? No, it's also verb.change? Or verb.cognition?

 Wait, the sense keys provided are:
 1. delay%2:30:00::
 2. delay%2:42:00::
 3. delay%2:30:01::
 4. delay%2:30:05::

 The second number is the lexicographer file number:
 - 30 = verb.change
 - 42 = verb.social? No, 42 is verb.social in some versions? Actually:
   - 29 = verb.body
   - 30 = verb.change
   - 31 = verb.cognition
   - ...
   - 41 = verb.possession
   - 42 = verb.social

 So sense 2 is in verb.social, which usually involves interactions between people. But "delay your application" could fit there.

 However, sense 1 (verb.change) is about causing a change in state (the state of being delayed).

 In the medical context, "treatment should be delayed" means the administration of treatment should be postponed. This is causing the treatment to occur at a later time than originally scheduled. This fits sense 1 best.

 Sense 3 is clearly wrong (stop/halt).
 Sense 4 is about retarding development, not postponing a scheduled event.

 So it's between 1 and 2.

 Sense 1: "cause to be slowed down or delayed" - focuses on the causation of the delay.
 Sense 2: "act later than planned" - focuses on the timing of the action.

 In "Treatment should be delayed", the treatment is the object of the delaying. Someone (the doctor) should cause the treatment to be delayed (postponed). This is sense 1.

 Also, the example "Traffic was delayed" is very similar to "Treatment should be delayed" - both are passive, both refer to events/processes being postponed.

 Therefore, the best sense is 1.

 Wait, I should double-check if there's any nuance I'm missing. In medical contexts, "delayed" often means "postponed" or "deferred". This is sense 1.

 Sense 2 might be interpreted as "the patient should delay (seeking treatment)" but that's not what the text says. It says "Treatment should be delayed" - the treatment itself is the object.

 So I'll go with sense 1.

provider: Phala


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: discontinue
Target surface form: discontinued
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or <t>discontinued</t>, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=discontinue%2:42:00:: | definition=put an end to a state or an activity | synonyms=stop, cease, give up, quit, lay off | examples=Quit teasing your little brother
2. sense_key=discontinue%2:42:01:: | definition=come to or be at an end | examples=the support from our sponsoring agency will discontinue after March 31
3. sense_key=discontinue%2:30:00:: | definition=prevent completion | synonyms=break, break off, stop | examples=stop the project; break off the negotiations

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "discontinued" in the given context. The target lemma is "discontinue" and the surface form is "discontinued".

Context analysis:
The sentence is: "Treatment should be delayed or <t>discontinued</t>, or the dose reduced, in patients whose blood counts are abnormal or who have certain other side effects."

This is a medical context about Alimta (a chemotherapy drug). The sentence discusses what should happen to the treatment when patients have abnormal blood counts or side effects. The options are: delay it, discontinue it, or reduce the dose.

Candidate senses:
1. discontinue%2:42:00:: - put an end to a state or an activity (synonyms: stop, cease, give up, quit, lay off)
2. discontinue%2:42:01:: - come to or be at an end (example: support will discontinue after March 31)
3. discontinue%2:30:00:: - prevent completion (synonyms: break, break off, stop; examples: stop the project; break off the negotiations)

Analysis:
- Sense 1 (discontinue%2:42:00::): This means to actively stop or cease an activity. In the context, the doctor would actively stop the treatment. This fits well with "put an end to a state or an activity" - the treatment is the activity being ended.
- Sense 2 (discontinue%2:42:01::): This is intransitive - "come to or be at an end". The example shows "support will discontinue" - the subject is the thing ending itself. In our context, "Treatment should be discontinued" - this is passive voice, but implies an agent (doctor) discontinuing it. However, sense 2 seems more like something that ends on its own or reaches its end naturally.
- Sense 3 (discontinue%2:30:00::): "prevent completion" - this seems different from stopping treatment. Preventing completion would mean stopping something before it's finished, but medical treatment is often ongoing/periodic rather than having a fixed "completion" point in the way a project does. While you could argue treatment has a course, "discontinue" in medical contexts usually means "stop administering" rather than "prevent from being completed".

Comparing senses 1 and 2:
Sense 1 is transitive: "put an end to [something]"
Sense 2 is intransitive: "come to an end"

In the sentence "Treatment should be discontinued", we have passive voice. The agent (doctor) would discontinue the treatment. This aligns with sense 1 (put an end to an activity). The treatment is the activity being ended by the medical professional.

Sense 2 would be more like "The treatment will discontinue after 3 weeks" (the treatment itself comes to an end).

Also, looking at the synonyms:
Sense 1: stop, cease, give up, quit, lay off
Sense 3: break, break off, stop

In medical contexts, "discontinue medication" or "discontinue treatment" almost always maps to sense 1 - the deliberate cessation of an ongoing activity.

The example for sense 1: "Quit teasing your little brother" - this is an imperative to stop an ongoing activity.
The example for sense 2: "the support from our sponsoring agency will discontinue after March 31" - this is about something ending, not being actively stopped by an external agent in the same way (though agencies can decide to end support, the syntax emphasizes the support itself ending).

The example for sense 3: "stop the project; break off the negotiations" - these are about preventing completion.

In the medical context, discontinuing treatment means stopping the administration of the drug, not necessarily preventing its completion (since treatment regimens can be open-ended or adjusted). The most straightforward interpretation is "put an end to" the treatment activity.

Therefore, sense 1 (discontinue%2:42:00::) is the best choice.

Wait, I need to check the sense indices. The user asks for a JSON object like {"sense_index": 3}. Looking at the candidate senses:
1. sense_key=discontinue%2:42:00::
2. sense_key=discontinue%2:42:01::
3. sense_key=discontinue%2:30:00::

So if I choose sense 1, the index is 1. If sense 2, index is 2. If sense 3, index is 3.

I believe sense 1 is correct.

Let me double-check WordNet definitions to be sure.
discontinue%2:42:00:: - "put an end to a state or an activity" - This is the transitive sense.
discontinue%2:42:01:: - "come to or be at an end" - This is the intransitive sense.

In "Treatment should be discontinued", the verb is used transitively in the passive voice. The subject (treatment) is having something done to it by an implied agent (the doctor). The doctor puts an end to the treatment. This is sense 1.

Sense 2 would be active intransitive: "The treatment discontinued" (meaning it came to an end).

Therefore, sense_index should be 1.

Actually, looking at the example for sense 2 again: "the support from our sponsoring agency will discontinue after March 31" - here "discontinue" is used intransitively (the support is the subject and it discontinues).

In our target sentence, "Treatment should be discontinued" - treatment is the subject of a passive verb. The active form would be "[The doctor] should discontinue treatment". This is clearly transitive.

Sense 1 is transitive: "put an end to [something]"
Sense 3 is also transitive: "prevent completion [of something]"

Between 1 and 3:
Sense 1 is about stopping an activity or state.
Sense 3 is about preventing completion.

Medical treatment is an ongoing activity. Stopping it is "putting an end to an activity". It's not necessarily about "preventing completion" because treatment doesn't always have a predefined completion point that we're interrupting - it might be ongoing maintenance therapy that is being stopped due to side effects.

Also, "discontinue" in pharmacological contexts is standardly sense 1.

Final check: The synonyms for sense 1 include "stop, cease, give up, quit, lay off". "Stop treatment" or "cease treatment" fit perfectly. "Give up treatment" or "quit treatment" are less formal but mean the same.
For sense 3: "break treatment", "break off treatment" - "break off" is possible but less standard than simply "stop".

Therefore, sense 1 is the correct choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the <t>dose</t> reduced, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the word "dose" in the given context.

Let me analyze the context:
The text is about Alimta, a chemotherapy drug. It mentions:
- "The recommended dose of Alimta is 500 mg per square metre..."
- "Treatment should be delayed or discontinued, or the <t>dose</t> reduced, in patients whose blood counts are abnormal..."

The target word "dose" appears in the phrase "the dose reduced" referring to reducing the amount of medication given to patients.

Now let's look at the candidate senses:

1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
   - This refers to a physical portion of medicine. In the context, "dose" is being reduced, which could fit, but let's check others.

2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
   - This refers to the quantity/amount of a substance. The context mentions "500 mg per square metre" which is a quantity measurement, and "the dose reduced" implies reducing the quantity.

3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact...
   - This is clearly wrong. This is the "dose" as slang for venereal disease (likely from "a dose of clap" or similar archaic usage). Not relevant here.

4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide...
   - This is slang for LSD. Not relevant in a medical chemotherapy context.

So it's between sense 1 and sense 2.

Sense 1 (dose%1:06:00::): "a measured portion of medicine taken at any one time" - This is in the noun.artifact (06) lexicographer file, referring to a physical thing.

Sense 2 (dose%1:23:00::): "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time" - This is in the noun.quantity (23) lexicographer file, referring to an amount/measurement.

In the context:
- "The recommended dose of Alimta is 500 mg per square metre..." - This is clearly referring to a quantity (500 mg), not a physical portion.
- "the dose reduced" - You reduce a quantity/measurement, not necessarily a physical portion in the sense of a pill or distinct object.

Also, looking at the WordNet hierarchy:
- Sense 1 is under noun.artifact (physical objects)
- Sense 2 is under noun.quantity (amounts, quantities)

Given that the text specifies "500 mg per square metre" and talks about calculating based on body surface area, this is clearly referring to a quantity/measurement of the drug, not a physical artifact.

Therefore, sense 2 (dose%1:23:00::) is the best fit.

Wait, let me double-check the WordNet sense keys to make sure I have the right indices.

The user provides:
1. sense_key=dose%1:06:00::
2. sense_key=dose%1:23:00::
3. sense_key=dose%1:26:00::
4. sense_key=dose%1:06:01::

So:
- Index 1: dose%1:06:00:: (measured portion of medicine)
- Index 2: dose%1:23:00:: (quantity of active agent)
- Index 3: dose%1:26:00:: (venereal disease)
- Index 4: dose%1:06:01:: (LSD)

The context is clearly medical, referring to the amount of Alimta (a chemotherapy drug) to be administered. The phrase "500 mg per square metre" indicates a quantity. While "dose" can refer to the physical medicine itself (sense 1), in medical contexts involving specific measurements like mg/m², it typically refers to the quantity (sense 2).

Also, the phrase "the dose reduced" makes more sense with a quantity than with a physical portion (though both could work). But the specific mention of "500 mg" strongly points to the quantity sense.

Therefore, the answer should be sense_index: 2.

Wait, I need to be careful. Let me check if there's any distinction I'm missing.

Sense 1: "a measured portion of medicine taken at any one time" - This could be interpreted as the amount prescribed/administered.
Sense 2: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time" - This emphasizes the quantity aspect.

Actually, looking at standard WSD datasets and how these senses are distinguished:
- Sense 1 often refers to the specific formulation/administration unit (like "take one dose of the syrup")
- Sense 2 refers to the amount/quantity concept (like "a high dose of radiation" or "500mg dose")

Given "500 mg per square metre", this is definitely the quantity sense (sense 2).

Also, looking at the synonyms: both have "dosage", but that doesn't help distinguish them.

The key is the hypernym hierarchy:
- 06 = noun.artifact (physical objects)
- 23 = noun.quantity

Since 500 mg is a measurement of quantity, not a physical object per se, sense 2 is correct.

Final check: Could sense 1 be correct? "A measured portion of medicine" - 500 mg could be considered a measured portion. But WordNet distinguishes between the physical portion (artifact) and the quantity. Given the mathematical calculation involved (per square metre of body surface area), this is treating dose as a quantitative measure.

Also, in the sentence "the dose reduced", you can reduce a quantity (sense 2) or reduce a portion (sense 1), but given the context of calculating based on body surface area and blood counts, it's the quantitative amount that matters.

Therefore, sense 2 is the best choice.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduced
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose <t>reduced</t>, in patients whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question
3. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
4. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
5. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
6. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
7. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
8. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
9. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
10. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
11. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
12. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
13. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
14. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
15. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
16. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
17. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
18. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
19. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
20. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation (WSD) for the word "reduced" in the given context. The target lemma is "reduce" and the surface form is "reduced".

 Let me analyze the context:
 - The text is about a medical treatment (Alimta, an anticancer chemotherapy drug)
 - It discusses dosing: "The recommended dose of Alimta is 500 mg per square metre..."
 - It mentions: "Treatment should be delayed or discontinued, or the dose <t>reduced</t>, in patients whose blood counts are abnormal or who have certain other side effects."

 So the context is about reducing the dose of medication. This means decreasing the amount/quantity of the dose.

 Now let's look at the candidate senses:

 1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
    - This seems to fit well. "Make a reduction in" applies to reducing a dose.

 2. sense_key=reduce%2:30:06:: | definition=make less complex
    - Not relevant here. Dose reduction isn't about complexity.

 3. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition
    - This is about humbling or weakening someone/something in a social/status sense, not about medication dosage.

 4. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation
    - Not relevant.

 5. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation
    - Not relevant to medication dosage.

 6. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down
    - Not relevant.

 7. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink
    - This is about physical size reduction. While dose could be seen as a quantity, this is more about physical dimensions (like shrinking a sweater).

 8. sense_key=reduce%2:40:00:: | definition=lessen and make more modest
    - "Lessen" could work, but "make more modest" suggests lifestyle or standards, not medical dosage.

 9. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down
    - This could work too. "Make smaller" or "scale down" a dose.

 10. sense_key=reduce%2:30:03:: | definition=chemistry term (remove oxygen...)
     - Not relevant.

 11. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten
     - This is about limiting scope/influx, not reducing quantity of a dose.

 12. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation
     - Not relevant.

 13. sense_key=reduce%2:35:00:: | definition=undergo meiosis
     - Biological process, not relevant.

 14. sense_key=reduce%2:35:01:: | definition=reposition a broken bone
     - Medical but wrong context.

 15. sense_key=reduce%2:30:12:: | definition=destress and weaken a sound
     - Phonetics, not relevant.

 16. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract
     - This is about abridging text or shortening scope, not about reducing a numeric quantity like dosage.

 17. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left
     - Cooking, not relevant.

 18. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left
     - Cooking, not relevant.

 19. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution
     - This is about diluting, which is different from reducing the dose amount.

 20. sense_key=reduce%2:29:00:: | definition=take off weight
     - Personal weight loss, not relevant.

 Now comparing sense 1 and sense 9:
 - Sense 1: "cut down on; make a reduction in" - examples include "reduce your daily fat intake", "cut back health benefits"
 - Sense 9: "make smaller" - example "reduce an image", synonym "scale down"

 In medical contexts, when we talk about reducing a dose, we typically mean decreasing the amount/quantity. Both could fit, but sense 1 ("make a reduction in", "cut down on") seems more appropriate for the context of reducing medication dosage. The example "reduce your daily fat intake" is analogous to reducing a drug dose - both involve decreasing the quantity of something consumed/administered.

 Sense 9 with "scale down" is more about physical size or proportion (like reducing an image), though it can be used for quantities.

 Also, looking at WordNet's organization:
 - Sense 1 (reduce%2:30:00::) is the first sense, often the most common/general one.
 - The gloss "cut down on; make a reduction in" fits perfectly with "reduce the dose".

 Let me verify the WordNet sense keys to make sure I understand the indexing:
 The format is reduce%2:30:00:: where the numbers represent lexicographer files and sense numbers.

 Actually, looking carefully at the candidate list, they are numbered 1-20 in the prompt, but these don't necessarily correspond to the WordNet sense numbers. The user asks for "sense_index" which likely refers to the number in the list (1-20).

 So I need to choose between index 1 and index 9 primarily.

 Index 1: "cut down on; make a reduction in" - This is about reducing intake, consumption, or amount of something. The examples show reducing fat intake and cutting back benefits.

 Index 9: "make smaller" - This is more about physical dimensions or scaling.

 In the medical context of "the dose reduced", we are talking about decreasing the quantity of medication given. This aligns better with sense 1 (making a reduction in the amount) than sense 9 (making physically smaller).

 Also, sense 8 mentions "lessen and make more modest" which is close but "make more modest" makes it less suitable for a technical medical context.

 Therefore, sense 1 (index 1) appears to be the best choice.

 Wait, let me double-check sense 30:00 vs others. The key reduce%2:30:00:: corresponds to the first one in my analysis.

 Actually, looking at the list again:
 1. sense_key=reduce%2:30:00::
 9. sense_key=reduce%2:30:04::

 In WordNet, reduce%2:30:00:: is indeed "cut down on; make a reduction in".
 And reduce%2:30:04:: is "make smaller".

 But in the context of drug dosing, "reduce the dose" means to decrease the amount, which is exactly "make a reduction in".

 I should confirm: is there any sense about reducing quantity specifically? Sense 1 seems to cover that with "make a reduction in".

 Also, looking at the example for sense 1: "reduce your daily fat intake" - this is exactly parallel to reducing a drug dose (daily drug intake).

 So the answer should be index 1.

 But wait, I should check if there's any other sense that might fit better. Sense 30:05 is "reduce in size; reduce physically" which might seem relevant, but that's about physical size (like shrinking clothes), not about decreasing a numerical quantity.

 Sense 30:04 "make smaller" with example "reduce an image" is also about size/scaling.

 So yes, sense 1 is the best fit.

 The JSON format should be: {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in <t>patients</t> whose blood counts are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
 The user wants me to perform Word Sense Disambiguation for the word "patients" in the given context.

 Target lemma: patient
 Target surface form: patients
 Context: Medical text about Alimta (a chemotherapy drug) and its administration to people undergoing treatment.

 Candidate senses:
 1. patient%1:18:00:: - "a person who requires medical care" (noun, person)
 2. patient%1:10:00:: - "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" (linguistic term, patient role)

 Analysis:
 - The context is clearly medical: "Alimta", "anticancer chemotherapy", "body surface area", "blood counts", "kidney problems", etc.
 - The word "patients" refers to people receiving medical treatment.
 - Sense 1 matches perfectly: "a person who requires medical care"
 - Sense 2 is a technical linguistic term (thematic role/patient role in grammar), which doesn't fit this medical context about actual people receiving drug treatment.

 Examples provided for sense 1: "the number of emergency patients has grown rapidly" - this confirms it's about medical patients.

 Therefore, the correct sense is sense 1 (patient%1:18:00::).

 The user wants the output as JSON: {"sense_index": 1}

 Wait, let me check the sense keys again to make sure I'm identifying the index correctly. The user lists:
 1. sense_key=patient%1:18:00:: ...
 2. sense_key=patient%1:10:00:: ...

 So sense_index should be 1.

 Important constraints:
 - Do not answer with a WordNet sense key
 - Return only a JSON object exactly like {"sense_index": 3}
 - Choose the single best indexed sense
 - Do not hedge

 So my answer should be: {"sense_index": 1}

provider: DigitalOcean


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: blood_count
Target surface form: blood counts
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose <t>blood counts</t> are abnormal or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=blood_count%1:23:00:: | definition=the number of red and white corpuscles in a blood sample
2. sense_key=blood_count%1:04:00:: | definition=the act of estimating the number of red and white corpuscles in a blood sample

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation on the target phrase "blood counts" in the given context.

 Target lemma: blood_count
 Target surface form: blood counts
 Context: Medical text about Alimta (a chemotherapy drug) treatment. The specific sentence is: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose <t>blood counts</t> are abnormal or who have certain other side effects."

 Candidate senses:
 1. sense_key=blood_count%1:23:00:: | definition=the number of red and white corpuscles in a blood sample
 2. sense_key=blood_count%1:04:00:: | definition=the act of estimating the number of red and white corpuscles in a blood sample

 Let me analyze the context:
 - The text discusses chemotherapy treatment (Alimta)
 - It mentions that treatment should be modified (delayed, discontinued, or dose reduced) based on whether patients' "blood counts" are abnormal
 - In medical contexts, when monitoring chemotherapy patients, doctors check the patient's blood cell counts (numbers of red blood cells, white blood cells, platelets) to determine if it's safe to continue treatment
 - The phrase "blood counts are abnormal" refers to the numerical values/results of the blood test, not the act of performing the test itself
 - If the counts (numbers) are too low (abnormal), treatment is delayed

 Sense 1 refers to the actual number/quantity of cells (the result/measurement).
 Sense 2 refers to the procedure/act of counting (the process).

 In the context "patients whose blood counts are abnormal", we are talking about the results/values being abnormal, not the procedure being abnormal. You wouldn't say "the act of estimating is abnormal" in this context. You would say "the numbers are abnormal."

 Therefore, Sense 1 is the correct choice.

 The sense index would be 1.

 Wait, let me double-check the sense keys:
 - sense_key=blood_count%1:23:00:: - This looks like the first sense (noun, usually 1:23 refers to a specific lexical file or sense number)
 - sense_key=blood_count%1:04:00:: - This is the second sense

 Actually, looking at WordNet sense key format: lemma%lexfile:lexid:headword:headid
 But the user has provided them as:
 1. sense_key=blood_count%1:23:00::
 2. sense_key=blood_count%1:04:00::

 So index 1 is the first one listed, index 2 is the second one listed.

 The question asks for the "sense_index" in the JSON. Based on the formatting of the candidate senses, they are numbered 1 and 2.

 Sense 1: the number of red and white corpuscles (the result)
 Sense 2: the act of estimating (the process)

 Context: "blood counts are abnormal" - This clearly refers to the numerical values, not the act of counting. In medical terminology, "blood counts" refers to the CBC (Complete Blood Count) results - the actual numbers.

 Therefore, the answer should be {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: abnormal
Target surface form: abnormal
Context:
Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose. Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are <t>abnormal</t> or who have certain other side effects. Alimta is not recommended for use in patients with moderate or severe kidney problems.

Candidate senses:
1. sense_key=abnormal%3:00:00:: | definition=not normal; not typical or usual or regular or conforming to a norm | synonyms=unnatural | examples=abnormal powers of concentration; abnormal amounts of rain
2. sense_key=abnormal%3:00:03:: | definition=departing from the normal in e.g. intelligence and development | examples=they were heartbroken when they learned their child was abnormal; an abnormal personality
3. sense_key=abnormal%5:00:00:immoderate:00 | definition=much greater than the normal | examples=abnormal profits; abnormal ambition

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The user wants me to perform Word Sense Disambiguation for the word "abnormal" in the given context.

 Context analysis:
 The text is about a medical drug called Alimta (pemetrexed). It discusses dosing, administration, and when treatment should be modified. The specific sentence is: "Treatment should be delayed or discontinued, or the dose reduced, in patients whose blood counts are <t>abnormal</t> or who have certain other side effects."

 So "abnormal" here refers to blood counts that are not within the normal range - they are atypical, unusual, or not conforming to the norm for healthy blood counts.

 Candidate sense analysis:

 1. sense_key=abnormal%3:00:00:: | definition=not normal; not typical or usual or regular or conforming to a norm | synonyms=unnatural | examples=abnormal powers of concentration; abnormal amounts of rain
    - This is the general sense of "not normal" or deviating from the norm.
    - Blood counts being abnormal fits this - they are not typical/usual/regular/conforming to the norm.
    - Examples include "abnormal amounts of rain" which is similar to abnormal blood counts (quantities that deviate from normal).

 2. sense_key=abnormal%3:00:03:: | definition=departing from the normal in e.g. intelligence and development | examples=they were heartbroken when they learned their child was abnormal; an abnormal personality
    - This sense is specifically about intelligence and development, personality.
    - The context is about blood counts, not intelligence or development.
    - This is too specific and doesn't fit.

 3. sense_key=abnormal%5:00:00:immoderate:00 | definition=much greater than the normal | examples=abnormal profits; abnormal ambition
    - This sense means "much greater than normal" - implying excess or immoderate.
    - While blood counts could be high, they could also be low (abnormal could mean either too high or too low).
    - The definition specifies "much greater than the normal" which is more specific than just "not normal."
    - Blood counts being abnormal in medical context usually means outside the reference range (either high or low), not specifically "much greater."
    - Also, the examples "abnormal profits" and "abnormal ambition" suggest excessive amounts, whereas blood counts could be abnormally low as well.

 Comparison:
 Sense 1 is the general "not normal" sense that applies to blood counts being outside the normal range.
 Sense 2 is specifically about psychological/developmental abnormalities.
 Sense 3 is about being excessive/immoderate.

 In medical contexts, "abnormal blood counts" means the values are outside the normal reference range - they are not typical, usual, or regular. This matches sense 1.

 The word "unnatural" as a synonym might seem odd for blood counts, but in the schematic WordNet sense, "abnormal" here clearly means "not conforming to a norm" (the normal range).

 Therefore, sense 1 (abnormal%3:00:00::) is the correct choice.

 Wait, I need to check the sense indices. The user asks for a JSON with "sense_index". Looking at the candidates:
 1. sense_key=abnormal%3:00:00::
 2. sense_key=abnormal%3:00:03::
 3. sense_key=abnormal%5:00:00:immoderate:00

 So the indices are 1, 2, and 3 as listed.

 I should choose sense_index: 1.

 Let me double-check sense 3. Could "abnormal blood counts" mean "much greater than normal"? In some contexts, maybe, but typically abnormal blood counts in chemotherapy monitoring refers to any deviation from normal - could be leukopenia (low white blood cells), thrombocytopenia (low platelets), etc. So it's not specifically "much greater." Also, the definition of sense 3 says "much greater than the normal" which is clearly about excess, whereas medical "abnormal" is about deviation from normal range in either direction.

 Sense 2 is clearly wrong as it's about intelligence/development.

 So sense 1 is definitely correct.

 The output should be: {"sense_index": 1}