[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
When they found it last winter, Dr. Vogelstein was dubious that the search was over. His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of <t>cancer</t> formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: formation
Target surface form: formation
Context:
When they found it last winter, Dr. Vogelstein was dubious that the search was over. His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer <t>formation</t>, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too.

Candidate senses:
1. sense_key=formation%1:14:00:: | definition=an arrangement of people or things acting as a unit | examples=a defensive formation; a formation of planes
2. sense_key=formation%1:04:00:: | definition=the act of fabricating something in a particular shape | synonyms=shaping
3. sense_key=formation%1:04:01:: | definition=the act of forming or establishing something | synonyms=constitution, establishment, organization, organisation | examples=the constitution of a PTA group last year; it was the establishment of his reputation
4. sense_key=formation%1:17:00:: | definition=(geology) the geological features of the earth | synonyms=geological formation
5. sense_key=formation%1:06:00:: | definition=a particular spatial arrangement
6. sense_key=formation%1:22:00:: | definition=natural process that causes something to form | examples=the formation of gas in the intestine; the formation of crystals
7. sense_key=formation%1:04:02:: | definition=creation by mental activity | examples=the formation of sentences; the formation of memories

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

service_tier: default

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: say
Target surface form: says
Context:
When they found it last winter, Dr. Vogelstein was dubious that the search was over. His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "<t>says</t> Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too.

Candidate senses:
1. sense_key=say%2:32:00:: | definition=express in words | synonyms=state, tell | examples=He said that he wanted to marry her; tell me what is bothering you
2. sense_key=say%2:32:01:: | definition=report or maintain | synonyms=allege, aver | examples=He alleged that he was the victim of a crime; He said it was too late to intervene in the war
3. sense_key=say%2:32:03:: | definition=express a supposition | synonyms=suppose | examples=Let us say that he did not tell the truth; Let's say you had a lot of money--what would you do?
4. sense_key=say%2:42:00:: | definition=have or contain a certain wording or form | synonyms=read | examples=The passage reads as follows; What does the law say?
5. sense_key=say%2:32:04:: | definition=give instructions to or direct somebody to do something with authority | synonyms=order, tell, enjoin | examples=I said to him to go home; She ordered him to do the shopping
6. sense_key=say%2:32:02:: | definition=speak, pronounce, or utter in a certain way | synonyms=pronounce, articulate, enounce, sound out, enunciate | examples=She pronounces French words in a funny way; I cannot say `zip wire'
7. sense_key=say%2:32:07:: | definition=communicate or express nonverbally | examples=What does this painting say?; Did his face say anything about how he felt?
8. sense_key=say%2:32:15:: | definition=utter aloud | examples=She said `Hello' to everyone in the office
9. sense_key=say%2:32:13:: | definition=state as one's opinion or judgement; declare | examples=I say let's forget this whole business
10. sense_key=say%2:32:08:: | definition=recite or repeat a fixed text | examples=Say grace; She said her `Hail Mary'
11. sense_key=say%2:32:09:: | definition=indicate | examples=The clock says noon

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: leader
Target surface form: leader
Context:
When they found it last winter, Dr. Vogelstein was dubious that the search was over. His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a <t>leader</t> in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too.

Candidate senses:
1. sense_key=leader%1:18:00:: | definition=a person who rules or guides or inspires others
2. sense_key=leader%1:06:00:: | definition=a featured article of merchandise sold at a loss in order to draw customers | synonyms=drawing card, loss leader

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: evidence
Target surface form: Evidence
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. <t>Evidence</t> now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=evidence%1:09:00:: | definition=your basis for belief or disbelief; knowledge on which to base belief | synonyms=grounds | examples=the evidence that smoking causes lung cancer is very compelling
2. sense_key=evidence%1:10:01:: | definition=an indication that makes something evident | examples=his trembling was evidence of his fear
3. sense_key=evidence%1:10:00:: | definition=(law) all the means by which any alleged matter of fact whose truth is investigated at judicial trial is established or disproved

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: now
Target surface form: now
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence <t>now</t> is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=now%4:02:05:: | definition=in the historical present; at this point in the narration of a series of past events | examples=President Kennedy now calls in the National Guard; Washington now decides to cross the Delaware
2. sense_key=now%4:02:00:: | definition=in these times; - Nancy Mitford | synonyms=nowadays, today | examples=it is solely by their language that the upper classes nowadays are distinguished; we now rarely see horse-drawn vehicles on city streets
3. sense_key=now%4:02:02:: | definition=used to preface a command or reproof or request | examples=now hear this!; now pay attention
4. sense_key=now%4:02:04:: | definition=at the present moment | synonyms=at present | examples=goods now on sale; the now-aging dictator
5. sense_key=now%4:02:01:: | definition=without delay or hesitation; with no time intervening | synonyms=immediately, instantly, straightaway, straight off, directly, right away | examples=he answered immediately; found an answer straightaway
6. sense_key=now%4:02:07:: | definition=(prefatory or transitional) indicates a change of subject or activity | examples=Now the next problem is...
7. sense_key=now%4:02:06:: | definition=in the immediate past | examples=told me just now

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: emerge
Target surface form: emerging
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is <t>emerging</t> that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=emerge%2:30:00:: | definition=come out into view, as from concealment | examples=Suddenly, the proprietor emerged from his office
2. sense_key=emerge%2:30:02:: | definition=come out of | synonyms=issue, come out, come forth, go forth, egress | examples=Water issued from the hole in the wall; The words seemed to come out by themselves
3. sense_key=emerge%2:30:01:: | definition=become known or apparent | examples=Some nice results emerged from the study
4. sense_key=emerge%2:38:00:: | definition=come up to the surface of or rise | examples=He felt new emotions emerge
5. sense_key=emerge%2:42:00:: | definition=happen or occur as a result of something | synonyms=come forth

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: involved
Target surface form: involved
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is <t>involved</t> in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=involved%3:00:00:: | definition=connected by participation or association or use | examples=we accomplished nothing, simply because of the large number of people involved; the problems involved
2. sense_key=involved%5:00:00:encumbered:00 | definition=entangled or hindered as if e.g. in mire | synonyms=mired | examples=the difficulties in which the question is involved; brilliant leadership mired in details and confusion
3. sense_key=involved%5:00:00:attached:01 | definition=emotionally involved
4. sense_key=involved%5:00:00:complex:00 | definition=highly complex or intricate and occasionally devious; ; ; ; ; ; ; ; - Sir Walter Scott | synonyms=Byzantine, convoluted, knotty, tangled, tortuous | examples=the Byzantine tax structure; Byzantine methods for holding on to his chairmanship
5. sense_key=involved%5:00:00:enclosed:00 | definition=enveloped | examples=a castle involved in mist; the difficulties in which the question is involved

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in <t>other</t> cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancers
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other <t>cancers</t>, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: too
Target surface form: too
Context:
His doubts stemmed from the fact that several years earlier a Princeton University researcher, Arnold Levine, had found in experiments with mice that a gene called p53 could transform normal cells into cancerous ones. The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, <t>too</t>. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies.

Candidate senses:
1. sense_key=too%4:02:00:: | definition=to a degree exceeding normal or proper limits | synonyms=excessively, overly, to a fault | examples=too big
2. sense_key=too%4:02:01:: | definition=in addition | synonyms=besides, also, likewise, as well | examples=he has a Mercedes, too

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: find
Target surface form: found
Context:
The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have <t>found</t> that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer.

Candidate senses:
1. sense_key=find%2:40:02:: | definition=come upon, as if by accident; meet with | synonyms=happen, chance, bump, encounter | examples=We find this idea in Plato; I happened upon the most wonderful bakery not very far from here
2. sense_key=find%2:39:02:: | definition=discover or determine the existence, presence, or fact of | synonyms=detect, observe, discover, notice | examples=She detected high levels of lead in her drinking water; We found traces of lead in the paint
3. sense_key=find%2:40:00:: | definition=come upon after searching; find the location of something that was missed or lost | synonyms=regain | examples=Did you find your glasses?; I cannot find my gloves!
4. sense_key=find%2:32:00:: | definition=establish after a calculation, investigation, experiment, survey, or study | synonyms=determine, find out, ascertain | examples=find the product of two numbers; The physicist who found the elusive particle won the Nobel Prize
5. sense_key=find%2:31:10:: | definition=come to believe on the basis of emotion, intuitions, or indefinite grounds | synonyms=feel | examples=I feel that he doesn't like me; I find him to be obnoxious
6. sense_key=find%2:39:01:: | definition=perceive or be contemporaneous with | synonyms=witness, see | examples=We found Republicans winning the offices; You'll see a lot of cheating in this school
7. sense_key=find%2:40:01:: | definition=get something or somebody for a specific purpose | synonyms=line up, get hold, come up | examples=I found this gadget that will serve as a bottle opener; I got hold of these tools to fix our plumbing
8. sense_key=find%2:36:00:: | definition=make a discovery, make a new finding | synonyms=discover | examples=Roentgen discovered X-rays; Physicists believe they found a new elementary particle
9. sense_key=find%2:31:09:: | definition=make a discovery | synonyms=discover | examples=She found that he had lied to her; The story is false, so far as I can discover
10. sense_key=find%2:40:03:: | definition=obtain through effort or management | examples=She found the time and energy to take care of her aging parents; We found the money to send our sons to college
11. sense_key=find%2:32:01:: | definition=decide on and make a declaration about | synonyms=rule | examples=find someone guilty
12. sense_key=find%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, obtain, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
13. sense_key=find%2:39:05:: | definition=perceive oneself to be in a certain condition or place | examples=I found myself in a difficult situation; When he woke up, he found himself in a hospital room
14. sense_key=find%2:40:15:: | definition=get or find back; recover the use of | synonyms=recover, retrieve, regain | examples=She regained control of herself; She found her voice and replied quickly
15. sense_key=find%2:38:10:: | definition=succeed in reaching; arrive at | examples=The arrow found its mark
16. sense_key=find%2:30:13:: | definition=accept and make use of one's personality, abilities, and situation | synonyms=find oneself | examples=My son went to Berkeley to find himself

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: breast
Target surface form: breast
Context:
The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 <t>breast</t> tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer.

Candidate senses:
1. sense_key=breast%1:08:01:: | definition=the front of the trunk from the neck to the abdomen | synonyms=chest | examples=he beat his breast in anger
2. sense_key=breast%1:08:00:: | definition=either of two soft fleshy milk-secreting glandular organs on the chest of a woman | synonyms=bosom, knocker, boob, tit, titty
3. sense_key=breast%1:13:00:: | definition=meat carved from the breast of a fowl | synonyms=white meat
4. sense_key=breast%1:05:00:: | definition=the part of an animal's body that corresponds to a person's chest

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: copy
Target surface form: copy
Context:
The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one <t>copy</t> of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer.

Candidate senses:
1. sense_key=copy%1:10:00:: | definition=a reproduction of a written record (e.g. of a legal or school record) | synonyms=transcript
2. sense_key=copy%1:06:00:: | definition=a thing made to be similar or identical to another thing | examples=she made a copy of the designer dress; the clone was a copy of its ancestor
3. sense_key=copy%1:10:01:: | definition=matter to be printed; exclusive of graphical materials | synonyms=written matter
4. sense_key=copy%1:10:02:: | definition=material suitable for a journalistic account | examples=catastrophes make good copy

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spot
Target surface form: spot
Context:
The deletion Dr. Vogelstein found was in exactly the same spot as p53. But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the <t>spot</t> where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer.

Candidate senses:
1. sense_key=spot%1:15:01:: | definition=a point located with respect to surface features of some region | synonyms=topographic point, place | examples=this is a nice place for a picnic; a bright spot on a planet
2. sense_key=spot%1:10:01:: | definition=a short section or illustration (as between radio or tv programs or in a magazine) that is often used for advertising
3. sense_key=spot%1:07:02:: | definition=an outstanding characteristic | synonyms=point | examples=his acting was one of the high points of the movie
4. sense_key=spot%1:07:00:: | definition=a blemish made by dirt | synonyms=smudge, blot, daub, smear, smirch, slur | examples=he had a smudge on his cheek
5. sense_key=spot%1:07:01:: | definition=a small contrasting part of something | synonyms=speckle, dapple, patch, fleck, maculation | examples=a bald spot; a leopard's spots
6. sense_key=spot%1:10:00:: | definition=a section of an entertainment that is assigned to a specific performer or performance | examples=they changed his spot on the program
7. sense_key=spot%1:06:00:: | definition=a business establishment for entertainment | examples=night spot
8. sense_key=spot%1:04:01:: | definition=a job in an organization | synonyms=position, post, berth, office, billet, place | examples=he occupied a post in the treasury
9. sense_key=spot%1:26:00:: | definition=a slight attack of illness | synonyms=touch | examples=he has a touch of rheumatism
10. sense_key=spot%1:23:00:: | definition=a small piece or quantity of something | synonyms=bit | examples=a spot of tea; a bit of paper
11. sense_key=spot%1:10:02:: | definition=a mark on a die or on a playing card (shape depending on the suit) | synonyms=pip
12. sense_key=spot%1:06:01:: | definition=a lamp that produces a strong beam of light to illuminate a restricted area; used to focus attention of a stage performer | synonyms=spotlight
13. sense_key=spot%1:06:02:: | definition=a playing card with a specified number of pips on it to indicate its value | examples=an eight-spot
14. sense_key=spot%1:04:00:: | definition=an act that brings discredit to the person who does it | synonyms=blot, smear, smirch, stain | examples=he made a huge blot on his copybook

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: say
Target surface form: say
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists <t>say</t> that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=say%2:32:00:: | definition=express in words | synonyms=state, tell | examples=He said that he wanted to marry her; tell me what is bothering you
2. sense_key=say%2:32:01:: | definition=report or maintain | synonyms=allege, aver | examples=He alleged that he was the victim of a crime; He said it was too late to intervene in the war
3. sense_key=say%2:32:03:: | definition=express a supposition | synonyms=suppose | examples=Let us say that he did not tell the truth; Let's say you had a lot of money--what would you do?
4. sense_key=say%2:42:00:: | definition=have or contain a certain wording or form | synonyms=read | examples=The passage reads as follows; What does the law say?
5. sense_key=say%2:32:04:: | definition=give instructions to or direct somebody to do something with authority | synonyms=order, tell, enjoin | examples=I said to him to go home; She ordered him to do the shopping
6. sense_key=say%2:32:02:: | definition=speak, pronounce, or utter in a certain way | synonyms=pronounce, articulate, enounce, sound out, enunciate | examples=She pronounces French words in a funny way; I cannot say `zip wire'
7. sense_key=say%2:32:07:: | definition=communicate or express nonverbally | examples=What does this painting say?; Did his face say anything about how he felt?
8. sense_key=say%2:32:15:: | definition=utter aloud | examples=She said `Hello' to everyone in the office
9. sense_key=say%2:32:13:: | definition=state as one's opinion or judgement; declare | examples=I say let's forget this whole business
10. sense_key=say%2:32:08:: | definition=recite or repeat a fixed text | examples=Say grace; She said her `Hail Mary'
11. sense_key=say%2:32:09:: | definition=indicate | examples=The clock says noon

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: often
Target surface form: often
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer <t>often</t> strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=often%4:02:00:: | definition=many times at short intervals | synonyms=frequently, oftentimes, oft, ofttimes | examples=we often met over a cup of coffee
2. sense_key=often%4:02:01:: | definition=frequently or in great quantities | synonyms=much, a great deal | examples=I don't drink much; I don't travel much
3. sense_key=often%4:02:02:: | definition=in many cases or instances

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: strike
Target surface form: strikes
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often <t>strikes</t> multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=strike%2:35:00:: | definition=deliver a sharp blow, as with the hand, fist, or weapon | examples=The teacher struck the child; the opponent refused to strike
2. sense_key=strike%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=affect, impress, move | examples=This child impressed me as unusually mature; This behavior struck me as odd
3. sense_key=strike%2:35:01:: | definition=hit against; come into sudden contact with | synonyms=hit, impinge on, run into, collide with | examples=The car hit a tree; He struck the table with his elbow
4. sense_key=strike%2:33:00:: | definition=make a strategic, offensive, assault against an enemy, opponent, or a target | synonyms=hit | examples=The Germans struck Poland on Sept. 1, 1939; We must strike the enemy's oil fields
5. sense_key=strike%2:32:00:: | definition=indicate (a certain time) by striking | examples=The clock struck midnight; Just when I entered, the clock struck
6. sense_key=strike%2:35:02:: | definition=affect or afflict suddenly, usually adversely | synonyms=hit | examples=We were hit by really bad weather; He was stricken with cancer when he was still a teenager
7. sense_key=strike%2:41:00:: | definition=stop work in order to press demands | synonyms=walk out | examples=The auto workers are striking for higher wages; The employees walked out when their demand for better benefits was not met
8. sense_key=strike%2:42:00:: | definition=touch or seem as if touching visually or audibly | synonyms=fall, shine | examples=Light fell on her face; The sun shone on the fields
9. sense_key=strike%2:41:02:: | definition=attain | synonyms=come to | examples=The horse finally struck a pace
10. sense_key=strike%2:35:03:: | definition=produce by manipulating keys or strings of musical instruments, also metaphorically | synonyms=hit | examples=The pianist strikes a middle C; strike `z' on the keyboard
11. sense_key=strike%2:30:00:: | definition=cause to form (an electric arc) between electrodes of an arc lamp | examples=strike an arc
12. sense_key=strike%2:40:00:: | definition=find unexpectedly | synonyms=fall upon, come upon, light upon, chance upon, come across, chance on | examples=the archeologists chanced upon an old tomb; she struck a goldmine
13. sense_key=strike%2:36:00:: | definition=produce by ignition or a blow | examples=strike fire from the flintstone; strike a match
14. sense_key=strike%2:35:08:: | definition=remove by erasing or crossing out or as if by drawing a line | synonyms=scratch, expunge, excise | examples=Please strike this remark from the record; scratch that remark
15. sense_key=strike%2:39:00:: | definition=cause to experience suddenly | synonyms=hit, come to | examples=Panic struck me; An interesting idea hit her
16. sense_key=strike%2:38:02:: | definition=drive something violently into a location | synonyms=hit | examples=he hit his fist on the table; she struck her head on the low ceiling
17. sense_key=strike%2:38:08:: | definition=occupy or take on | synonyms=assume, take, take up | examples=He assumes the lotus position; She took her seat on the stage
18. sense_key=strike%2:36:02:: | definition=form by stamping, punching, or printing | synonyms=mint, coin | examples=strike coins; strike a medal
19. sense_key=strike%2:35:10:: | definition=smooth with a strickle | synonyms=strickle | examples=strickle the grain in the measure
20. sense_key=strike%2:35:09:: | definition=pierce with force | examples=The bullet struck her thigh; The icy wind struck through our coats
21. sense_key=strike%2:31:00:: | definition=arrive at after reckoning, deliberating, and weighing | examples=strike a balance; strike a bargain

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: member
Target surface form: members
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple <t>members</t> of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=member%1:18:00:: | definition=one of the persons who compose a social group (especially individuals who have joined and participate in a group organization) | synonyms=fellow member | examples=only members will be admitted; a member of the faculty
2. sense_key=member%1:24:00:: | definition=anything that belongs to a set or class | examples=snakes are members of the class Reptilia; members of the opposite sex
3. sense_key=member%1:08:00:: | definition=an external body part that projects from the body | synonyms=extremity, appendage | examples=it is important to keep the extremities warm
4. sense_key=member%1:14:00:: | definition=an organization that is a member of another organization (especially a state that belongs to a group of nations) | examples=the library was a member of the interlibrary loan association; Canada is a member of the United Nations
5. sense_key=member%1:08:01:: | definition=the male organ of copulation (`member' is a euphemism) | synonyms=penis, phallus

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: certain
Target surface form: certain
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of <t>certain</t> families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=certain%5:00:00:definite:00 | definition=definite but not specified or identified | examples=set aside a certain sum each week; to a certain degree
2. sense_key=certain%3:00:02:: | definition=having or feeling no doubt or uncertainty; confident and assured | synonyms=sure | examples=felt certain of success; was sure (or certain) she had seen it
3. sense_key=certain%3:00:01:: | definition=established beyond doubt or question; definitely known | examples=what is certain is that every effect must have a cause; it is certain that they were on the bus
4. sense_key=certain%3:00:03:: | definition=certain to occur; destined or inevitable; ; ; - Benjamin Franklin | synonyms=sure | examples=he was certain to fail; his fate is certain
5. sense_key=certain%3:00:05:: | definition=established irrevocably | synonyms=sealed | examples=his fate is sealed
6. sense_key=certain%5:00:00:reliable:00 | definition=reliable in operation or effect | synonyms=sure | examples=a quick and certain remedy; a sure way to distinguish the two
7. sense_key=certain%5:00:00:careful:00 | definition=exercising or taking care great enough to bring assurance | synonyms=sure | examples=be certain to disconnect the iron when you are through; be sure to lock the doors

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: family
Target surface form: families
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain <t>families</t>, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=family%1:14:02:: | definition=a social unit living together | synonyms=household, house, home, menage | examples=he moved his family to Virginia; It was a good Christian household
2. sense_key=family%1:14:00:: | definition=primary social group; parents and children | synonyms=family unit | examples=he wanted to have a good job before starting a family
3. sense_key=family%1:14:04:: | definition=a collection of things sharing a common attribute | synonyms=class, category | examples=there are two classes of detergents
4. sense_key=family%1:14:01:: | definition=people descended from a common ancestor | synonyms=family line, folk, kinfolk, kinsfolk, sept, phratry | examples=his family has lived in Massachusetts since the Mayflower
5. sense_key=family%1:18:00:: | definition=a person having kinship with another or others | synonyms=kin, kinsperson | examples=he's kin; he's family
6. sense_key=family%1:14:03:: | definition=(biology) a taxonomic group containing one or more genera | examples=sharks belong to the fish family
7. sense_key=family%1:14:06:: | definition=a loose affiliation of gangsters in charge of organized criminal activities | synonyms=syndicate, crime syndicate, mob
8. sense_key=family%1:14:05:: | definition=an association of people who share common beliefs or activities | synonyms=fellowship | examples=the message was addressed not just to employees but to every member of the company family; the church welcomed new members into its fellowship

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: inherit
Target surface form: inherited
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when <t>inherited</t> in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=inherit%2:40:00:: | definition=obtain from someone after their death | examples=I inherited a castle from my French grandparents
2. sense_key=inherit%2:40:02:: | definition=receive from a predecessor | examples=The new chairman inherited many problems from the previous chair
3. sense_key=inherit%2:40:01:: | definition=receive by genetic transmission | examples=I inherited my good eyesight from my mother

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: damaged
Target surface form: damaged
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a <t>damaged</t> form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=damaged%3:00:00:: | definition=harmed or injured or spoiled | examples=I won't buy damaged goods; the storm left a wake of badly damaged buildings
2. sense_key=damaged%5:00:00:disreputable:00 | definition=being unjustly brought into disrepute | synonyms=discredited | examples=a discredited politician; her damaged reputation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: form
Target surface form: form
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged <t>form</t>, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=form%1:10:00:: | definition=the phonological or orthographic sound or appearance of a word that can be used to describe or identify something | synonyms=word form, signifier, descriptor | examples=the inflected forms of a word can be represented by a stem and a list of inflections to be attached
2. sense_key=form%1:09:01:: | definition=a category of things distinguished by some common characteristic or quality | synonyms=kind, sort, variety | examples=sculpture is a form of art; what kinds of desserts are there?
3. sense_key=form%1:09:00:: | definition=a perceptual structure | synonyms=shape, pattern | examples=the composition presents problems for students of musical form; a visual pattern must include not only objects but the spaces between them
4. sense_key=form%1:07:01:: | definition=any spatial attributes (especially as defined by outline) | synonyms=shape, configuration, contour, conformation | examples=he could barely make out their shapes
5. sense_key=form%1:08:00:: | definition=alternative names for the body of a human being | synonyms=human body, physical body, material body, soma, build, figure | examples=Leonardo studied the human body; he has a strong physique
6. sense_key=form%1:03:00:: | definition=the spatial arrangement of something as distinct from its substance | synonyms=shape | examples=geometry is the mathematical science of shape
7. sense_key=form%1:07:00:: | definition=the visual appearance of something or someone | synonyms=shape, cast | examples=the delicate cast of his features
8. sense_key=form%1:10:01:: | definition=a printed document with spaces in which to write | examples=he filled out his tax form
9. sense_key=form%1:14:02:: | definition=(biology) a group of organisms within a species that differ in trivial ways from similar groups | synonyms=variant, strain, var. | examples=a new strain of microorganisms
10. sense_key=form%1:10:02:: | definition=an arrangement of the elements in a composition or discourse | examples=the essay was in the form of a dialogue; he first sketches the plot in outline form
11. sense_key=form%1:07:03:: | definition=a particular mode in which something is manifested | examples=his resentment took the form of extreme hostility
12. sense_key=form%1:26:00:: | definition=(physical chemistry) a distinct state of matter in a system; matter that is identical in chemical composition and physical state and separated from other material by the phase boundary | synonyms=phase | examples=the reaction occurs in the liquid phase of the system
13. sense_key=form%1:14:00:: | definition=a body of students who are taught together | synonyms=class, grade, course | examples=early morning classes are always sleepy
14. sense_key=form%1:07:02:: | definition=an ability to perform well | examples=he was at the top of his form; the team was off form last night
15. sense_key=form%1:06:00:: | definition=a life-size dummy used to display clothes | synonyms=mannequin, manikin, mannikin, manakin
16. sense_key=form%1:06:01:: | definition=a mold for setting concrete | examples=they built elaborate forms for pouring the foundation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: woman
Target surface form: women
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose <t>women</t> to the cancer. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=woman%1:18:00:: | definition=an adult female person (as opposed to a man) | synonyms=adult female | examples=the woman kept house while the man hunted
2. sense_key=woman%1:18:01:: | definition=a female person who plays a significant role (wife or mistress or girlfriend) in the life of a particular man | examples=he was faithful to his woman
3. sense_key=woman%1:18:02:: | definition=a human female employed to do housework | synonyms=charwoman, char, cleaning woman, cleaning lady | examples=the char will clean the carpet; I have a woman who comes in four hours a day while I write
4. sense_key=woman%1:14:00:: | definition=women as a class | synonyms=womanhood, fair sex | examples=it's an insult to American womanhood; woman is the glory of creation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
But Mr. Levine had said the p53 gene caused cancer by promoting growth, whereas the Johns Hopkins scientists were looking for a gene that suppressed growth. Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the <t>cancer</t>. The p53 gene has just been implicated in lung cancer.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: implicate
Target surface form: implicated
Context:
Despite that, when the Johns Hopkins scientists compared the gene they had found in the human cancer cells with the Mr. Levine's p53 gene they found the two were identical; it turned out that in Mr. Levine's cancer studies, he had unknowingly been observing a damaged form of p53 -- a cancer-suppressing gene. The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been <t>implicated</t> in lung cancer. In a report out last week, John Minna and colleagues at the National Cancer Institute say that about half the cells taken from lung cancer tissue they tested are missing this gene.

Candidate senses:
1. sense_key=implicate%2:42:01:: | definition=bring into intimate and incriminating connection | examples=He is implicated in the scheme to defraud the government
2. sense_key=implicate%2:42:00:: | definition=impose, involve, or imply as a necessary accompaniment or result | synonyms=entail | examples=What does this move entail?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: report
Target surface form: report
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a <t>report</t> out last week, John Minna and colleagues at the National Cancer Institute say that about half the cells taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=report%1:10:03:: | definition=a written document describing the findings of some individual or group | synonyms=study, written report | examples=this accords with the recent study by Hill and Dale
2. sense_key=report%1:10:01:: | definition=the act of informing by verbal report | synonyms=account | examples=he heard reports that they were causing trouble; by all accounts they were a happy couple
3. sense_key=report%1:10:00:: | definition=a short account of the news | synonyms=news report, story, account, write up | examples=the report of his speech; the story was on the 11 o'clock news
4. sense_key=report%1:11:00:: | definition=a sharp explosive sound (especially the sound of a gun firing) | examples=they heard a violent report followed by silence
5. sense_key=report%1:10:04:: | definition=a written evaluation of a student's scholarship and deportment | synonyms=report card | examples=his father signed his report card
6. sense_key=report%1:10:02:: | definition=an essay (especially one written as an assignment) | synonyms=composition, paper, theme | examples=he got an A on his composition
7. sense_key=report%1:09:00:: | definition=the general estimation that the public has for a person | synonyms=reputation | examples=he acquired a reputation as an actor before he started writing; he was a person of bad report

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: last
Target surface form: last
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a report out <t>last</t> week, John Minna and colleagues at the National Cancer Institute say that about half the cells taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=last%5:00:00:past:00 | definition=immediately past | examples=last Thursday; the last chapter we read
2. sense_key=last%3:00:00:: | definition=coming after all others in time or space or degree or being the only one remaining | examples=the last time I saw Paris; the last day of the month
3. sense_key=last%5:00:00:closing:00 | definition=occurring at or forming an end or termination | synonyms=concluding, final, terminal | examples=his concluding words came as a surprise; the final chapter
4. sense_key=last%5:00:00:unlikely:00 | definition=most unlikely or unsuitable | examples=the last person we would have suspected; the last man they would have chosen for the job
5. sense_key=last%5:00:00:dying:00 | definition=occurring at the time of death | examples=his last words; the last rites
6. sense_key=last%5:00:00:ultimate:00 | definition=conclusive in a process or progression | synonyms=final, net | examples=the final answer; a last resort
7. sense_key=last%5:00:00:high:02 | definition=highest in extent or degree | synonyms=utmost | examples=to the last measure of human endurance; whether they were accomplices in the last degree or a lesser one was...to be determined individually
8. sense_key=last%5:00:00:unalterable:00 | definition=not to be altered or undone | synonyms=final | examples=the judge's decision is final; the arbiter will have the last say
9. sense_key=last%5:00:00:worst:00 | definition=lowest in rank or importance | synonyms=last-place, lowest | examples=last prize; in last place

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: week
Target surface form: week
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a report out last <t>week</t>, John Minna and colleagues at the National Cancer Institute say that about half the cells taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=week%1:28:00:: | definition=any period of seven consecutive days | synonyms=hebdomad | examples=it rained for a week
2. sense_key=week%1:28:01:: | definition=hours or days of work in a calendar week | synonyms=workweek | examples=they worked a 40-hour week
3. sense_key=week%1:28:02:: | definition=a period of seven consecutive days starting on Sunday | synonyms=calendar week

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: say
Target surface form: say
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a report out last week, John Minna and colleagues at the National Cancer Institute <t>say</t> that about half the cells taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=say%2:32:00:: | definition=express in words | synonyms=state, tell | examples=He said that he wanted to marry her; tell me what is bothering you
2. sense_key=say%2:32:01:: | definition=report or maintain | synonyms=allege, aver | examples=He alleged that he was the victim of a crime; He said it was too late to intervene in the war
3. sense_key=say%2:32:03:: | definition=express a supposition | synonyms=suppose | examples=Let us say that he did not tell the truth; Let's say you had a lot of money--what would you do?
4. sense_key=say%2:42:00:: | definition=have or contain a certain wording or form | synonyms=read | examples=The passage reads as follows; What does the law say?
5. sense_key=say%2:32:04:: | definition=give instructions to or direct somebody to do something with authority | synonyms=order, tell, enjoin | examples=I said to him to go home; She ordered him to do the shopping
6. sense_key=say%2:32:02:: | definition=speak, pronounce, or utter in a certain way | synonyms=pronounce, articulate, enounce, sound out, enunciate | examples=She pronounces French words in a funny way; I cannot say `zip wire'
7. sense_key=say%2:32:07:: | definition=communicate or express nonverbally | examples=What does this painting say?; Did his face say anything about how he felt?
8. sense_key=say%2:32:15:: | definition=utter aloud | examples=She said `Hello' to everyone in the office
9. sense_key=say%2:32:13:: | definition=state as one's opinion or judgement; declare | examples=I say let's forget this whole business
10. sense_key=say%2:32:08:: | definition=recite or repeat a fixed text | examples=Say grace; She said her `Hail Mary'
11. sense_key=say%2:32:09:: | definition=indicate | examples=The clock says noon

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: about
Target surface form: about
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a report out last week, John Minna and colleagues at the National Cancer Institute say that <t>about</t> half the cells taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=about%4:02:00:: | definition=(of quantities) imprecise but fairly close to correct | synonyms=approximately, close to, just about, some, roughly, more or less | examples=lasted approximately an hour; in just about a minute
2. sense_key=about%4:02:06:: | definition=all around or on all sides | synonyms=around | examples=dirty clothes lying around (or about); let's look about for help
3. sense_key=about%4:02:01:: | definition=in the area or vicinity | synonyms=around | examples=a few spectators standing about; hanging around
4. sense_key=about%4:02:04:: | definition=used of movement to or among many different places or in no particular direction | synonyms=around | examples=wandering about with no place to go; people were rushing about
5. sense_key=about%4:02:02:: | definition=in or to a reversed position or direction | synonyms=around | examples=about face; suddenly she turned around
6. sense_key=about%4:02:03:: | definition=in rotation or succession | examples=turn about is fair play
7. sense_key=about%4:02:05:: | definition=(of actions or states) slightly short of or not quite accomplished; all but | synonyms=almost, most, nearly, near, nigh, virtually | examples=the job is (just) about done; the baby was almost asleep when the alarm sounded

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cells
Context:
The discovery "suddenly puts an obscure gene right in the cockpit of cancer formation, "says Robert Weinberg, a leader in cancer-gene research at Whitehead Institute in Cambridge, Mass. Evidence now is emerging that the p53 suppressor gene is involved in other cancers, too. Researchers in Edinburgh, Scotland, have found that in 23 of 38 breast tumors, one copy of chromosome 17 was mutated at the spot where gene p53 lies. The scientists say that since breast cancer often strikes multiple members of certain families, the gene, when inherited in a damaged form, may predispose women to the cancer. The p53 gene has just been implicated in lung cancer. In a report out last week, John Minna and colleagues at the National Cancer Institute say that about half the <t>cells</t> taken from lung cancer tissue they tested are missing this gene. There also are reports from several labs, as yet unpublished, of missing p53 genes in tissue taken from kidney, brain and skin cancers.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.