[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
1.  **Analyze the Target Word**: The target lemma is "use", and the surface form is "used". The specific context is: "How is Alimta <t>used</t>?" and the surrounding text describes the medical application of a drug (Alimta) for treating cancer.

2.  **Analyze the Context**:
    *   The text talks about a medicine called Alimta.
    *   The sentence "How is Alimta used?" asks about the method or procedure of applying/administering the medicine.
    *   The following sentence says: "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
    *   Previous sentences say: "Alimta is used to treat two types of cancer...", "Alimta is used together with cisplatin...".
    *   The core meaning here is employing a substance (the drug) for a specific purpose (treating cancer). It involves putting the drug into service for its intended medical purpose.

3.  **Evaluate Candidate Senses**:

    *   **Sense 1**: `use%2:34:01::` | definition="put into service; make work or employ for a particular purpose or for its inherent or natural purpose" | synonyms=utilize, utilise, apply, employ.
        *   *Analysis*: This fits perfectly. Using a drug to treat a disease is employing it for a particular purpose. The examples "use your head", "we only use Spanish at home" show general employment of things/abilities for a purpose.
        *   *Match*: Strong.

    *   **Sense 2**: `use%2:34:02::` | definition="take or consume (regularly or habitually)" | synonyms=habituate | examples="She uses drugs rarely".
        *   *Analysis*: While this involves drugs, "uses drugs" in this sense usually refers to substance abuse or taking a substance into the body. Here, the context is clinical/medical administration ("treat cancer", "given under supervision"). Sense 2 is more about the act of consumption (often with a connotation of recreational use or habitual taking), whereas the text is about the *application* of a medical treatment. However, one *does* "use" medicine. But compare Sense 1 ("apply", "employ") vs Sense 2 ("consume"). In the sentence "How is Alimta used?", the question is asking about the *procedure* (putting it into service), not just the act of swallowing it or the habit of taking it. The text explains the *purpose* (treating cancer). Sense 1 covers "employ for a particular purpose". Sense 2 is narrower (habitual consumption). Sense 1 is broader and fits the professional medical context of employing a tool/drug for a cure.

    *   **Sense 3**: `use%2:34:00::` | definition="use up, consume fully" | synonyms=expend.
        *   *Analysis*: This means to deplete resources. Not applicable here.

    *   **Sense 4**: `use%2:41:14::` | definition="seek or achieve an end by using to one's advantage".
        *   *Analysis*: This implies exploitation or maneuvering (e.g., "using friends"). Not applicable to a drug treating a disease.

    *   **Sense 5**: `use%2:41:04::` | definition="avail oneself to" | synonyms=practice, apply.
        *   *Analysis*: Examples are "apply a principle", "practice a religion". This is abstract. While "apply" is a synonym, Sense 1 is more concrete for physical objects/tools like medicine. Sense 1 has "apply" as a synonym too. Sense 1 is the general "put into service". Sense 5 is often for abstract concepts. Medicine is a concrete substance (in this context). Sense 1 is better.

    *   **Sense 6**: `use%2:41:03::` | definition="habitually do something (use only in the past tense)".
        *   *Analysis*: This is the "used to" construction (auxiliary verb). The context is "How is Alimta used?". This is passive voice ("be used"), not the auxiliary "used to" describing past habits. The form is "is used", which is passive voice of the lexical verb "use". Sense 6 is ruled out.

4.  **Refining the choice between Sense 1 and Sense 2**:
    *   Sense 1: "employ for a particular purpose". The text says Alimta is used *to treat* cancer. This indicates purpose.
    *   Sense 2: "take or consume". While patients take Alimta, the sentence "Alimta is used to treat..." focuses on the function/purpose of the agent (Alimta) rather than the patient's consumption habit. When asking "How is Alimta used?", one answers regarding dosage, combination, and administration method (employment). Therefore, Sense 1 is the correct linguistic classification for employing an agent for a function.

5.  **Conclusion**: Sense 1 is the best fit. The medicine is employed/applied for the purpose of treating cancer.

    *   Sense 1 matches "put into service" (the drug is put into service).
    *   Sense 1 matches "employ for a particular purpose" (treating cancer).
    *   Synonyms like "apply" fit the medical context (application of a treatment).

6.  **Final Output Generation**:
    *   Target sense: 1.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
Let me analyze the target word "only" in the given context:

The sentence is: "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

Let me consider each sense:

1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
- This sense means "and nothing more" or "merely/simply/just". For example, "I was merely asking" means I was just asking, nothing more.

2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
- This sense means "exclusively" or "solely" - meaning something is done by itself, without anything else being involved.

3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
- This sense is about a result that happens despite expectations, often translated as "only to".

4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
- This sense is about the ultimate outcome or consequence.

5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
- This sense is used to introduce an exception or contrast.

6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
- This sense is conditional, meaning something happens only under certain conditions.

7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago
- This sense indicates recency.

Now, in the context: "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

The word "only" here is indicating a restriction or limitation - Alimta should be given exclusively under the supervision of a qualified doctor. It means that this is the sole condition under which it should be given - no other conditions are acceptable.

This matches sense 2: "without any others being included or involved" with synonyms like "exclusively, solely, alone".

The meaning is: Alimta should be given solely/exclusively under the supervision of a qualified doctor - no other way of giving it is acceptable.

So the best indexed sense is 2.

format: unknown

native_finish_reason: stop

provider: DigitalOcean

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the context:**
    *   Sentence: "Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."
    *   Subject: "Alimta" (a medicine/drug).
    *   Verb: "given" (passive voice).
    *   Object (implicit in active voice): To a patient (implied by the context of treating cancer).
    *   Adverbial phrase: "under the supervision of a doctor..."
    *   Meaning: The drug Alimta is administered to patients. This is a medical context regarding the administration of a pharmaceutical product.

2.  **Evaluate the candidate senses:**

    *   *Sense 1 (cause to have...):* Too broad. "She gave him a black eye" is physical injury/casual. "Alimta" is a specific medicinal substance.
    *   *Sense 2 (be the cause or source of):* Not fitting. Alimta isn't a source of trouble in this context; it's being administered.
    *   *Sense 3 (transfer possession...):* "I gave her my money." A bit too generic. While possession is transferred, the medical context usually implies administration rather than a simple hand-over of ownership. You don't "own" the drug in the same way you own money; you receive a dose.
    *   *Sense 4 (convey or reveal information):* Incorrect.
    *   *Sense 5 (convey... compliment...):* Incorrect.
    *   *Sense 6 (organize...):* Incorrect.
    *   *Sense 7 (convey... smile...):* Incorrect.
    *   *Sense 8 (give as a present...):* Incorrect. Drugs aren't presents.
    *   *Sense 9 (cause to happen...):* Incorrect.
    *   *Sense 10 (dedicate...):* Incorrect.
    *   *Sense 11 (give or supply...):* "The cow brings in 5 liters of milk". Close, as in "supplying" a result. But Alimta isn't producing something like milk; it's being administered to a patient.
    *   *Sense 17 (place into the hands or custody of):* "hand me the spoon". This is the physical act of handing something over. While a nurse might hand a pill to a patient, "given" in a medical context (especially intravenous or serious chemotherapy) usually refers to the act of administration/treatment, not just the physical hand-off. However, it is a strong contender for "giving" objects.
    *   *Sense 19 (give (as medicine)):* Definition: "give (as medicine)". Example: "I gave him the drug".
        *   Context match: "Alimta" is a medicine (anticancer chemotherapy).
        *   Sentence: "Alimta should only be given..." matches "I gave him the drug".
        *   This sense specifically targets the medical administration of a drug. It fits perfectly.

3.  **Compare Sense 17 and Sense 19:**
    *   Sense 17 ("place into the hands or custody of") focuses on the physical transfer of an object.
    *   Sense 19 ("give (as medicine)") focuses on the administration of a medicinal substance.
    *   In the sentence "Alimta should only be given under the supervision of a doctor...", the emphasis is on the act of medical administration (likely an infusion or injection for chemotherapy, or at least a monitored event), not simply passing a bottle of pills across a counter. The example "I gave him the drug" aligns directly with "Alimta [a drug] ... given". Sense 19 is the specialized WordNet sense for this context.

4.  **Final verification:**
    *   Target: "given"
    *   Context: Medical administration of Alimta.
    *   Sense 19 definition: "give (as medicine)".
    *   Sense 19 example: "I gave him the drug".
    *   This is a precise match.

5.  **Construct the JSON:**
    *   The sense index for "give%2:40:13::" is 19.

provider: Novita


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: doctor
Target surface form: doctor
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the target word**: "doctor" (lemma: "doctor", surface form: "doctor").
2.  **Analyze the context**:
    *   The text discusses "Alimta", a medicine used to treat cancer.
    *   It mentions prescriptions, chemotherapy, and doses calculated by body surface area.
    *   Specific sentence: "Alimta should only be given under the supervision of a **doctor** who is qualified in the use of anticancer chemotherapy."
    *   The context clearly refers to a medical professional administering treatment.
3.  **Evaluate Candidate Senses**:
    *   *Sense 1*: "a licensed medical practitioner" (synonyms: doc, physician, MD, Dr., medico). This fits perfectly. The context talks about administering medicine, supervision of chemotherapy, and prescribing. This is the role of a medical doctor/physician.
    *   *Sense 2*: "(Roman Catholic Church) a title conferred on 33 saints..." This is a religious title, unrelated to administering chemotherapy drugs.
    *   *Sense 3*: "children take the roles of physician..." This refers to a game children play. It does not fit the serious medical context of administering Alimta.
    *   *Sense 4*: "a person who holds Ph.D. degree..." While someone with a Ph.D. might be involved in research, the context specifies "qualified in the use of anticancer chemotherapy" and supervising the administration of the drug to patients, which implies a medical doctor (MD) rather than just an academic Ph.D.
4.  **Select the best sense**: Sense 1 is the correct definition for a medical practitioner.
5.  **Format the output**: The user requested a JSON object with the key "sense_index". Sense 1 corresponds to index 1.

Final check:
- Context: Medical treatment, chemotherapy.
- Word: doctor.
- Sense 1: Licensed medical practitioner.
- Fit: Perfect.
- Output format: JSON {"sense_index": 1}.

provider: Together


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: use
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
Let me analyze the context and the candidate senses for the target word "use" in the sentence:

"The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy."

Here, "use" appears in the phrase "qualified in the use of anticancer chemotherapy." This refers to the act or practice of administering/using the anticancer chemotherapy. It's talking about the action or practice of using the chemotherapy, not the purpose or function of it.

Let me check each sense:

1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers

This sense refers to "the act of using" with examples like "he warned against the use of narcotic drugs" and "skilled in the utilization of computers." The context is about being qualified in the use (act/practice) of anticancer chemotherapy. This seems to fit well.

2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?

This is about the purpose or function of something, not the act of using it. This doesn't fit well.

3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses

This refers to a particular service, which doesn't fit the context about chemotherapy.

4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily

This is specifically about economics and consumption, which doesn't fit the medical context.

5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair

This is about psychological habits, which doesn't fit the context.

6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous

This is about manipulation, which doesn't fit the context.

7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

This is a legal definition about property rights, which doesn't fit the medical context.

The best match is sense 1, which refers to "the act of using." The context talks about being qualified in the use (act/practice) of anticancer chemotherapy, similar to the example "skilled in the utilization of computers." Both refer to the act or practice of using something, not the purpose or function of it.

So the answer is {"sense_index":1}.

provider: DeepInfra


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended <t>dose</t> of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the Target Word and Context:**
    *   Target lemma: `dose`
    *   Target surface form: `dose`
    *   Context: The text discusses "Alimta," an anticancer medicine used with cisplatin. It mentions prescriptions, doctors, chemotherapy, and intravenous infusions. Specifically, the target sentence is: "The recommended *dose* of Alimta is 500 mg per square metre of body surface area..."

2.  **Analyze the Candidate Senses:**
    *   **Sense 1:** `dose%1:06:00::` | Definition: "a measured portion of medicine taken at any one time" | Synonyms: `dosage`. This refers specifically to *medicine*.
    *   **Sense 2:** `dose%1:23:00::` | Definition: "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time" | Synonyms: `dosage`. This is a broader definition including any active agent (substance or radiation), not just medicine.
    *   **Sense 3:** `dose%1:26:00::` | Definition: "a communicable infection..." | Synonyms: `venereal disease...`. This is unrelated to the context of administering chemotherapy.
    *   **Sense 4:** `dose%1:06:01::` | Definition: "street name for lysergic acid diethylamide" | Synonyms: `acid...`. This refers to LSD, irrelevant to the medical context of cancer treatment.

3.  **Evaluate Sense 1 vs. Sense 2:**
    *   The context is explicitly about a "medicine" (Alimta, cisplatin).
    *   Sense 1 specifies "medicine".
    *   Sense 2 specifies "active agent (substance or radiation)".
    *   In WordNet, the hierarchy (lexical file) often distinguishes between general substances and specific medicinal preparations.
    *   Sense 1 belongs to the "artifact" or "medicine" domain (lexicographer file 06: possession).
    *   Sense 2 belongs to the "substance" domain (lexicographer file 23: substance).
    *   Alimta is a specific pharmaceutical product (a medicine).
    *   While a medicine *is* an active agent, Sense 1 is the specialized sense for "medicine". In WSD, if a specific sense (medicine) exists and fits perfectly, it is usually preferred over a more general sense (active agent), especially when the synonym "dosage" is shared but the domain is specific.
    *   Let's check the definitions closely.
        *   Sense 1: "measured portion of medicine".
        *   Sense 2: "quantity of an active agent...".
    *   The context talks about a "prescription," "anticancer chemotherapy," and "medicine." The target phrase is "recommended dose of Alimta." Alimta is defined as a medicine in the text ("medicines for cancer").
    *   Therefore, Sense 1 is the most precise fit because the agent is explicitly identified as medicine. Sense 2 is hyper-hyponymous or a sibling that covers radiation and generic substances. Since Alimta is a medicine, Sense 1 is the intended meaning.

4.  **Conclusion:**
    *   Sense 1 is the correct choice.

5.  **Format Output:**
    *   JSON object: `{"sense_index": 1}`

provider: Baidu


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: mg
Target surface form: mg
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=mg%1:23:00:: | definition=one thousandth (1/1,000) gram | synonyms=milligram
2. sense_key=mg%1:27:00:: | definition=a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) | synonyms=magnesium, atomic number 12

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the Request:**
    *   Target lemma: "mg"
    *   Target surface form: "mg"
    *   Context: A medical text describing the dosage of the drug Alimta (pemetrexed). Specifically: "The recommended dose of Alimta is 500 mg per square metre of body surface area..."
    *   Candidate senses:
        *   Sense 1: milligram (unit of mass).
        *   Sense 2: magnesium (chemical element).
    *   Output format: JSON `{"sense_index": X}`.

2.  **Analyze the Context:**
    *   The sentence is: "The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area..."
    *   Keywords: "dose", "Alimta", "500", "per square metre".
    *   Meaning: The text discusses the quantity of a drug administered to a patient.
    *   Logic: Drugs are measured in units of mass (or concentration). "500 mg" refers to a specific mass of the active ingredient. It does not refer to the chemical element magnesium in this context (which would be a substance, not a unit of measurement).

3.  **Evaluate Candidate Senses:**
    *   **Sense 1 (milligram):** Definition: "one thousandth (1/1,000) gram". Synonyms: "milligram". This fits perfectly. Drug dosages are commonly measured in milligrams.
    *   **Sense 2 (magnesium):** Definition: "...ductile bivalent metallic element...". Synonyms: "magnesium". This does not fit the context of a dosage measurement unit. While drugs might contain elements, "500 mg" here is a unit quantifying the amount, not the element magnesium itself.

4.  **Select the Best Sense:**
    *   Sense 1 is clearly the correct interpretation of "mg" in a medical dosage context.

5.  **Format the Output:**
    *   The user requested only a JSON object.
    *   The index corresponds to the list numbering (1 or 2).
    *   Selected index: 1.

6.  **Final Output Generation:**
    *   `{"sense_index": 1}`


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the target word and context:**
    *   Target lemma: "body"
    *   Target surface form: "body"
    *   Context snippet: "The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight)."

2.  **Analyze the specific usage:**
    *   The phrase is "body surface area". This is a medical dosing calculation (BSA).
    *   It refers to the surface area of a living human organism (the patient).
    *   The context mentions "patient", "height and weight", "cancer", "medicine".
    *   It refers to the physical structure of the patient.

3.  **Evaluate the candidate senses:**

    *   **Sense 1:** `body%1:08:00::` | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure.
        *   This fits perfectly. "Body surface area" refers to the surface area of the entire physical structure of the patient. The calculation uses height and weight to determine the size of this organism.

    *   **Sense 2:** `body%1:14:00::` | definition=a group of persons associated by some common tie or occupation and regarded as an entity.
        *   Incorrect. This refers to a collective group (e.g., student body).

    *   **Sense 3:** `body%1:08:02::` | definition=a natural object consisting of a dead animal or person.
        *   Incorrect. The patient is alive (receiving chemotherapy).

    *   **Sense 4:** `body%1:17:00::` | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects.
        *   This is too abstract/generic. While a human body is a 3D object, in medical contexts referring to patients, the specific biological sense (organism) is preferred over the generic physical object sense. "Body surface area" specifically relates to the anatomy of the organism.

    *   **Sense 5:** `body%1:08:01::` | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk.
        *   Incorrect. Body surface area (BSA) includes the limbs, head, and trunk. It is the whole body.

    *   **Sense 6:** `body%1:14:02::` | definition=a collection of particulars considered as a system.
        *   Incorrect. (e.g., body of law).

    *   **Sense 7:** `body%1:07:00::` | definition=the property of holding together and retaining its shape.
        *   Incorrect. (e.g., consistency of dough).

    *   **Sense 8:** `body%1:10:00::` | definition=the central message of a communication.
        *   Incorrect.

    *   **Sense 9:** `body%1:07:01::` | definition=the main mass of a thing.
        *   Incorrect. Too vague.

    *   **Sense 10:** `body%1:06:01::` | definition=a resonating chamber in a musical instrument.
        *   Incorrect.

    *   **Sense 11:** `body%1:06:00::` | definition=the external structure of a vehicle.
        *   Incorrect.

4.  **Select the best match:**
    *   Sense 1 is the definition of "body" as the entire structure of an organism. "Body surface area" is a measurement of the external surface of this organism. Therefore, sense 1 is the correct choice.

5.  **Format the output:**
    *   The user wants a JSON object `{"sense_index": X}`.
    *   The chosen sense is index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: calculate
Target surface form: calculated
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (<t>calculated</t> using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=calculate%2:31:00:: | definition=make a mathematical calculation or computation | synonyms=cipher, cypher, compute, work out, reckon, figure
2. sense_key=calculate%2:31:03:: | definition=judge to be probable | synonyms=estimate, reckon, count on, figure, forecast
3. sense_key=calculate%2:40:00:: | definition=keep an account of | synonyms=account
4. sense_key=calculate%2:32:01:: | definition=predict in advance | synonyms=forecast
5. sense_key=calculate%2:31:02:: | definition=specifically design a product, event, or activity for a certain public | synonyms=aim, direct
6. sense_key=calculate%2:31:05:: | definition=have faith or confidence in | synonyms=count, bet, depend, look, reckon | examples=you can count on me to help you any time; Look to your friends for support

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
1.  **Analyze the Target Word:** The target lemma is "calculate", appearing as the past participle "calculated" in a passive construction ("...calculated using the patient's height and weight").

2.  **Analyze the Context:** The sentence is "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight)."
    *   The context describes a medical dosage determination.
    *   It involves a mathematical process: Body Surface Area (BSA) is derived from height and weight using a specific formula (like the Mosteller formula or Du Bois formula).
    *   The core meaning here is performing a computation based on inputs (height and weight) to get a result (body surface area).

3.  **Analyze the Candidate Senses:**

    *   **Sense 1:** `calculate%2:31:00::` | definition="make a mathematical calculation or computation" | synonyms="cipher, cypher, compute, work out, reckon, figure".
        *   *Analysis:* This fits perfectly. The text describes determining a numerical value (surface area) using inputs (height/weight). "Compute" is a strong synonym here.

    *   **Sense 2:** `calculate%2:31:03::` | definition="judge to be probable" | synonyms="estimate, reckon, count on, figure, forecast".
        *   *Analysis:* This implies uncertainty or probability (e.g., "I calculate the risks are high"). While BSA involves estimation in a physiological sense, in the context of the text, it is a precise mathematical derivation, not a judgment of probability.

    *   **Sense 3:** `calculate%2:40:00::` | definition="keep an account of" | synonyms="account".
        *   *Analysis:* This relates to bookkeeping or tracking items. Not relevant to deriving body surface area.

    *   **Sense 4:** `calculate%2:32:01::` | definition="predict in advance" | synonyms="forecast".
        *   *Analysis:* This is about future prediction. BSA calculation is a current measurement derivation, not a weather forecast or stock prediction.

    *   **Sense 5:** `calculate%2:31:02::` | definition="specifically design a product, event, or activity for a certain public" | synonyms="aim, direct".
        *   *Analysis:* This is usually used in contexts like "The program is calculated to appeal to teenagers." Not relevant here.

    *   **Sense 6:** `calculate%2:31:05::` | definition="have faith or confidence in" | synonyms="count, bet, depend, look, reckon".
        *   *Analysis:* This is idiomatic (e.g., "I calculate on your support"). Not relevant here.

4.  **Conclusion:** The text explicitly mentions deriving a number ("500 mg per square metre") using specific variables ("height and weight"). This is a mathematical computation. Sense 1 ("make a mathematical calculation or computation") matches this exactly.

5.  **Format Output:** The user requested a JSON object with the sense index.
    *   Sense 1 matches.
    *   JSON: `{"sense_index": 1}`.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: using
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated <t>using</t> the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the target word:**
    *   Target lemma: `use`
    *   Target surface form: `using`
    *   Context snippet: "...calculated using the patient s height and weight."

2.  **Analyze the context:**
    *   The sentence describes how a dose is calculated.
    *   "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight)."
    *   The height and weight are *employed* or *utilized* to perform a calculation.
    *   The subject (implied, the doctor or the method) is "putting into service" the data (height and weight) to achieve a result (body surface area).

3.  **Evaluate Candidate Senses:**

    *   **Sense 1:** `use%2:34:01::` | Definition: "put into service; make work or employ for a particular purpose or for its inherent or natural purpose" | Synonyms: utilize, utilise, apply, employ | Examples: "use your head!"; "we only use Spanish at home".
        *   *Analysis:* This fits perfectly. The calculation *employs* height and weight. It *utilizes* the data for a specific purpose (calculation). The structure "calculated using X" is synonymous with "calculated by employing X".

    *   **Sense 2:** `use%2:34:02::` | Definition: "take or consume (regularly or habitually)" | Synonyms: habituate | Examples: "She uses drugs rarely".
        *   *Analysis:* This refers to consumption or addiction. It does not fit the calculation context.

    *   **Sense 3:** `use%2:34:00::` | Definition: "use up, consume fully" | Synonyms: expend | Examples: "The legislature expended its time on school questions".
        *   *Analysis:* This refers to depletion. We are not "using up" the height and weight; we are employing them as variables.

    *   **Sense 4:** `use%2:41:14::` | Definition: "seek or achieve an end by using to one's advantage" | Examples: "She uses her influential friends to get jobs".
        *   *Analysis:* This implies exploitation or instrumentalizing someone/something for personal gain (often negative connotation or specific agency). While "using data" is instrumental, this sense usually targets "using *someone*". More importantly, Sense 1 is the general "employ" sense, which is the standard sense for "using X to calculate Y". Sense 4 is more about leveraging a resource/asset for an advantage, often personified or strategic. Here, it's a standard functional application.

    *   **Sense 5:** `use%2:41:04::` | Definition: "avail oneself to" | Synonyms: practice, apply | Examples: "apply a principle"; "practice a religion".
        *   *Analysis:* This is about following a custom, principle, or method. You don't "avail oneself to" height and weight in this context. You employ them.

    *   **Sense 6:** `use%2:41:03::` | Definition: "habitually do something (use only in the past tense)" | Examples: "She used to call her mother...".
        *   *Analysis:* This is the "used to" construction (auxiliary verb usage). The target form is "using" (present participle), so this sense is grammatically impossible.

4.  **Conclusion:**
    *   Sense 1 is the standard transitive verb meaning "to employ or utilize something for a purpose."
    *   In the phrase "calculated using the patient's height and weight," the height and weight are the instruments/data employed to perform the calculation.
    *   Sense 1 is the best fit.

5.  **Final Output Formulation:**
    *   The prompt asks for a JSON object with the sense index.
    *   Sense 1 corresponds to index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patient
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the <t>patient</t> s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the Request:**
    *   Target lemma: "patient"
    *   Target surface form: "patient"
    *   Context: A text describing the usage of the drug Alimta for lung cancer patients. The specific target token is in the phrase "...calculated using the <t>patient</t> s height and weight".
    *   Candidate senses:
        1.  `patient%1:18:00::`: A person who requires medical care. (Example: "the number of emergency patients has grown rapidly").
        2.  `patient%1:10:00::`: The semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause. (Synonyms: affected role, patient role).
    *   Output format: JSON `{"sense_index": N}`.

2.  **Analyze the Context:**
    *   The text is about a medical drug (Alimta) and its administration.
    *   The sentence containing the target word: "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient's height and weight)."
    *   The word "patient" here refers to the person receiving the medical treatment (the person whose height and weight are used to calculate the dosage).
    *   The broader context mentions "patients who have not received chemotherapy", "patients who have not been treated before", etc.

3.  **Analyze the Senses:**
    *   **Sense 1 (`patient%1:18:00::`):** Definition: "a person who requires medical care".
        *   Does this fit? Yes. The context is about calculating a dose for a specific person receiving medical treatment. The word "patient" here is a noun referring to the sick or treated person. This is the standard, everyday medical definition of "patient".
    *   **Sense 2 (`patient%1:10:00::`):** Definition: "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause".
        *   Does this fit? No. This is a linguistic/semantic role definition (like "subject", "object", "agent", "patient"). It describes a grammatical function or a thematic relation in linguistics. For example, in the sentence "John hit the ball," the ball is the patient (semantic role). While the entity in the text *is* the semantic patient of the treatment verbs (receiving the drug), the word "patient" in the text is not being used *to denote* the semantic role. It is being used as a lexical noun to denote the person.
        *   Contrast: If the text were "In this sentence, 'the dog' plays the patient," then Sense 2 would be appropriate. Here, the text is "calculated using the patient's height and weight," referring to the human being.

4.  **Compare and Decide:**
    *   The word "patient" in "the patient's height and weight" refers to the human being receiving medical attention.
    *   Sense 1 matches "person requiring medical care".
    *   Sense 2 matches a linguistic abstraction (thematic role).
    *   The text is a medical instruction/information leaflet, not a linguistic treatise.
    *   Therefore, Sense 1 is the correct choice.

5.  **Formulate Output:**
    *   The index for the chosen sense is 1.
    *   JSON format: `{"sense_index": 1}`.

provider: StreamLake


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: height
Target surface form: height
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s <t>height</t> and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=height%1:07:00:: | definition=the vertical dimension of extension; distance from the base of something to the top | synonyms=tallness
2. sense_key=height%1:26:00:: | definition=the highest level or degree attainable; the highest stage of development | synonyms=acme, elevation, peak, pinnacle, summit, superlative | examples=his landscapes were deemed the acme of beauty; the artist's gifts are at their acme
3. sense_key=height%1:07:01:: | definition=(of a standing person) the distance from head to foot | synonyms=stature
4. sense_key=height%1:07:02:: | definition=elevation especially above sea level or above the earth's surface | synonyms=altitude | examples=the altitude gave her a headache

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the Context:** The target word is "height". The sentence is: "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight)."
    *   The context talks about calculating body surface area (BSA).
    *   BSA calculation requires the patient's physical measurements.
    *   The measurements listed are "height and weight".
    *   This clearly refers to the physical stature of a human being.

2.  **Analyze the Candidate Senses:**
    *   **Sense 1:** "the vertical dimension of extension; distance from the base of something to the top" (synonyms: tallness).
        *   This is the general geometric definition. It applies to buildings, trees, mountains, etc. While a person has a height, this sense is less specific than Sense 3 regarding human subjects.
    *   **Sense 2:** "the highest level or degree attainable; the highest stage of development" (synonyms: acme, peak, etc.).
        *   This is metaphorical. "The height of fashion." Not applicable here.
    *   **Sense 3:** "(of a standing person) the distance from head to foot" (synonyms: stature).
        *   This is the specific definition for human height. The context mentions a "patient". "Stature" is a perfect synonym in this medical context. The definition explicitly mentions "standing person" and "distance from head to foot".
    *   **Sense 4:** "elevation especially above sea level or above the earth's surface" (synonyms: altitude).
        *   This refers to geographical location. "Flying at a great height." Not applicable to a patient's measurement.

3.  **Compare and Select:**
    *   Sense 1 is the hypernym (general term).
    *   Sense 3 is the hyponym (specific term for humans).
    *   In Word Sense Disambiguation, if a specific sense exists for the context (human stature), it is usually preferred over the general geometric sense.
    *   The phrase "patient's height" strongly correlates with Sense 3's definition "(of a standing person)".

4.  **Formulate the Output:**
    *   The best sense is Sense 3.
    *   The required output format is a JSON object: `{"sense_index": 3}`.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: weight
Target surface form: weight
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and <t>weight</t>). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=weight%1:07:00:: | definition=the vertical force exerted by a mass as a result of gravity
2. sense_key=weight%1:06:01:: | definition=sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms | synonyms=free weight, exercising weight
3. sense_key=weight%1:07:01:: | definition=the relative importance granted to something | synonyms=weightiness | examples=his opinion carries great weight; the progression implied an increasing weightiness of the items listed
4. sense_key=weight%1:06:00:: | definition=an artifact that is heavy
5. sense_key=weight%1:12:00:: | definition=an oppressive feeling of heavy force | examples=bowed down by the weight of responsibility
6. sense_key=weight%1:23:01:: | definition=a system of units used to express the weight of something | synonyms=system of weights
7. sense_key=weight%1:23:00:: | definition=a unit used to measure weight | synonyms=weight unit | examples=he placed two weights in the scale pan
8. sense_key=weight%1:23:02:: | definition=(statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance | synonyms=weighting

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
1.  **Analyze the target word and context:**
    *   Target lemma: weight
    *   Target surface form: weight
    *   Context: "...calculated using the patient s height and weight."
    *   Domain: Medical/Pharmacological instructions for dosing.
    *   Meaning: The "weight" here refers to the patient's body mass or heaviness, used to calculate body surface area (BSA) for dosage determination.

2.  **Analyze the candidate senses:**

    *   *Sense 1:* `weight%1:07:00::` | definition=the vertical force exerted by a mass as a result of gravity.
        *   This is the physics definition ($W = mg$). While related to body mass, in a medical context regarding a patient's weight, we are usually referring to the measure of mass (often used interchangeably with mass in common parlance), but technically, this definition describes the force. However, in WordNet hierarchies, this sense often covers the general concept of how heavy something is. Let's look at other options to see if there is a better fit for "body weight".

    *   *Sense 2:* `weight%1:06:01::` | definition=sports equipment used in calisthenic exercises...
        *   Clearly incorrect. No dumbbells involved.

    *   *Sense 3:* `weight%1:07:01::` | definition=the relative importance granted to something.
        *   Figurative meaning. Incorrect.

    *   *Sense 4:* `weight%1:06:00::` | definition=an artifact that is heavy.
        *   Refers to an object (like a paperweight). Incorrect.

    *   *Sense 5:* `weight%1:12:00::` | definition=an oppressive feeling of heavy force.
        *   Figurative/Emotional. Incorrect.

    *   *Sense 6:* `weight%1:23:01::` | definition=a system of units used to express the weight of something.
        *   Refers to the *system* (e.g., imperial system), not the value itself. Incorrect.

    *   *Sense 7:* `weight%1:23:00::` | definition=a unit used to measure weight.
        *   Refers to the *unit* (e.g., a pound, a kilogram), not the quantity. Incorrect.

    *   *Sense 8:* `weight%1:23:02::` | definition=(statistics) a coefficient assigned to elements...
        *   Statistical/Mathematical term, but specific to frequency distributions. Not "body weight".

3.  **Re-evaluating Sense 1 vs the lack of a specific "body weight" sense:**
    *   The candidates provided are limited.
    *   Sense 1 defines "weight" as "the vertical force exerted by a mass as a result of gravity". This is the scientific definition. In WordNet 3.0/3.1, this sense (`weight%1:07:00::`) is often the top-level definition for the physical property of weight.
    *   Is there a sense for "body weight" or "measure of heaviness"?
    *   Let's check the definitions again.
        *   Sense 1 is a physical attribute.
        *   Sense 4 is an artifact.
        *   Sense 7 is a unit.
    *   In standard WordNet, the "heaviness" or "amount that something weighs" falls under Sense 1 (`weight%1:07:00::`). Even though the definition mentions gravity and force, the hyponyms often include things related to specific weights, but the core concept of "a person's weight" maps to the physical property defined in Sense 1.
    *   Let's verify the hierarchy or usage. If I say "I want to lose weight", I am referring to the physical quantity. If I say "measure height and weight", I am referring to the physical property.
    *   The definition "the vertical force exerted by a mass..." is technically accurate for the physics concept, but in common and medical usage, this node represents the physical property of being heavy.
    *   None of the other senses fit. Sense 4 is an object ("an artifact"). Sense 7 is a unit of measurement. Sense 6 is a system.
    *   Therefore, Sense 1 is the correct choice among the options, representing the physical property of weight.

4.  **Double Check:**
    *   Context: "patient s height and weight".
    *   Target: Physical property/mass.
    *   Candidate 1: "the vertical force exerted by a mass as a result of gravity". This is the standard WordNet definition for the physical quantity "weight".
    *   Is there any ambiguity with "an artifact that is heavy"? No, a patient is not an artifact used for weighing down things.
    *   Is there any ambiguity with "unit"? No, the text says "weight" (the attribute), not "kilograms" (the unit).

    *   Conclusion: Sense 1 is the intended sense in the WordNet structure for the physical property.

5.  **Final Selection:**
    *   Index 1.

    *   Let's double-check the index mapping.
    *   1 -> weight%1:07:00:: (vertical force...)
    *   2 -> weight%1:06:01:: (sports equipment)
    *   3 -> weight%1:07:01:: (relative importance)
    *   4 -> weight%1:06:00:: (artifact)
    *   5 -> weight%1:12:00:: (oppressive feeling)
    *   6 -> weight%1:23:01:: (system of units)
    *   7 -> weight%1:23:00:: (unit)
    *   8 -> weight%1:23:02:: (statistics)

    *   The context describes the patient's physical weight. In WordNet, the physical attribute of weight is defined as "the vertical force exerted by a mass as a result of gravity" (Sense 1). While the definition is physics-oriented, this is the synset used for the general concept of weight (heaviness).

    *   Example check: WordNet examples for Sense 1 usually include things like "he threw his weight around" or similar. Wait, actually, let's look at how WordNet distinguishes "mass" vs "weight". WordNet often conflates them in usage examples.
    *   Regardless, Sense 1 is the only candidate describing the physical phenomenon/attribute. Sense 4 is an object. Sense 7 is a unit.
    *   Therefore, Index 1 is the correct answer.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
The target word is "given" in the context:
"It is given once every three weeks as an intravenous infusion lasting 10 minutes."

Let me analyze this context:
- The subject is "It" referring to "Alimta" which is a medicine/drug
- The action is administering the medicine intravenously
- The context is about medical treatment - giving/administering a drug to a patient

Let me look at the candidate senses:

1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
- This is about causing someone to have something, not quite right for administering medicine

2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
- Not about causing something, it's about administering

3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
- This is about transferring possession, not quite right for medical administration

4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
- Not about information

5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
- Not about compliments or regards

6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
- Not about organizing

7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
- Not about gestures

8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
- Not about gifts

9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
- Not about causing events

10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
- Not about dedication

11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
- This is about supplying/producing something, not quite right

12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
- Not about knowledge or skills

13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
- Not about bringing about

14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
- Not about temporary giving

15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
- Not about emitting sounds

16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
- Not about sacrifice

17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
- This could work but it's more about physical handing over

18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
- Not about dedication

19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
- This is exactly about administering medicine! The example "I gave him the drug" matches the context perfectly.

20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
- This could also work for physical administration, but sense 19 is more specific

21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
- Not about bestowing

22. sense_key=give:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
- Not about official bestowal

23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
- Not about moving

24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
- Not about food

25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
- Not about contribution

26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
- Not about collapsing

27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
- Not about estimation

28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
- Not about execution

29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
- Not about exchange

30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
- Not about access

31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
- Not about presenting

32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
- Not about performance

33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
- Not about flexibility

34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
- Not about proposing

35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
- Not about verdicts

36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
- Not about manifesting

37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
- Not about offering in good faith

38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
- Not about submitting

39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
- Not about guiding

40. sense_key=give%2:32:10:: | definition=allow to have or take | examples=I give you two minutes to respond
- Not about allowing

41. sense_key=give%2:32:07:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
- Not about punishment

42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
- Not about occurring

43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
- Not about sex

44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
- Not about proffering body parts

The clear best match is sense 19: sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug

The context is about administering Alimta (a chemotherapy medicine) to patients intravenously. Sense 19 explicitly mentions "give (as medicine)" with the example "I gave him the drug" which perfectly matches this medical administration context.