[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: last
Target surface form: last
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then <t>last</t> spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=last%5:00:00:past:00 | definition=immediately past | examples=last Thursday; the last chapter we read
2. sense_key=last%3:00:00:: | definition=coming after all others in time or space or degree or being the only one remaining | examples=the last time I saw Paris; the last day of the month
3. sense_key=last%5:00:00:closing:00 | definition=occurring at or forming an end or termination | synonyms=concluding, final, terminal | examples=his concluding words came as a surprise; the final chapter
4. sense_key=last%5:00:00:unlikely:00 | definition=most unlikely or unsuitable | examples=the last person we would have suspected; the last man they would have chosen for the job
5. sense_key=last%5:00:00:dying:00 | definition=occurring at the time of death | examples=his last words; the last rites
6. sense_key=last%5:00:00:ultimate:00 | definition=conclusive in a process or progression | synonyms=final, net | examples=the final answer; a last resort
7. sense_key=last%5:00:00:high:02 | definition=highest in extent or degree | synonyms=utmost | examples=to the last measure of human endurance; whether they were accomplices in the last degree or a lesser one was...to be determined individually
8. sense_key=last%5:00:00:unalterable:00 | definition=not to be altered or undone | synonyms=final | examples=the judge's decision is final; the arbiter will have the last say
9. sense_key=last%5:00:00:worst:00 | definition=lowest in rank or importance | synonyms=last-place, lowest | examples=last prize; in last place

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Word "Last" in Context**

Okay, so the task is to decipher the meaning of "last" in "Then last spring, researchers reported finding a gene called p53..." Let's break this down. My initial thought is to consider the most likely senses in this particular context. I'll need to go through the available senses and quickly eliminate the less plausible ones.

First, "immediately past" seems like a strong contender, given the phrase "last spring." The example "last Thursday" feels spot-on. Then there's "coming after all others" – that could work if we're talking about the final spring of something, which could be relevant, but maybe not in this case. "Occurring at or forming an end" seems less likely, as does "most unlikely or unsuitable." "Occurring at the time of death," "conclusive in a process," and "highest in extent or degree" are clearly not applicable here. And the senses relating to unalterable and worst definitely don't fit.

Therefore, sense 1, "immediately past," is the clear winner: This is referring to the most recent spring, the spring that directly preceded the present moment. So, sense index 1 it is.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spring
Target surface form: spring
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last <t>spring</t>, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=spring%1:28:00:: | definition=the season of growth | synonyms=springtime | examples=the emerging buds were a sure sign of spring; he will hold office until the spring of next year
2. sense_key=spring%1:06:00:: | definition=a metal elastic device that returns to its shape or position when pushed or pulled or pressed | examples=the spring was broken
3. sense_key=spring%1:17:00:: | definition=a natural flow of ground water | synonyms=fountain, outflow, outpouring, natural spring
4. sense_key=spring%1:15:00:: | definition=a point at which water issues forth
5. sense_key=spring%1:07:00:: | definition=the elasticity of something that can be stretched and returns to its original length | synonyms=give, springiness
6. sense_key=spring%1:04:00:: | definition=a light, self-propelled movement upwards or forwards | synonyms=leap, leaping, saltation, bound, bounce

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
**Disambiguating "Spring" in Context**

Okay, so I'm looking at this phrase "last spring" and need to figure out which meaning of "spring" is being used. Let's see...I've got a few options here: the season, a metal device, a natural flow of water, a point where water comes out, the elasticity of something, or a quick movement. Given the sentence "Then last <t>spring</t>, researchers reported finding a gene called p53...", it's pretty obvious, even without context beyond the word itself, that we're talking about the season. No other sense fits the timeframe implied by "last."

So, that rules out all the other definitions. We're left with the first sense, which perfectly aligns with "the season of growth," also known as springtime. The other options really don't fit the sentence's narrative at all. Therefore, sense index 1, the seasonal one, is the definitive choice here. Case closed.

type: thinking

service_tier: default

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: report
Target surface form: reported
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers <t>reported</t> finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=report%2:32:00:: | definition=to give an account or representation of in words | synonyms=describe, account | examples=Discreet Italian police described it in a manner typically continental
2. sense_key=report%2:32:04:: | definition=announce as the result of an investigation or experience or finding | examples=Dozens of incidents of wife beatings are reported daily in this city; The team reported significant advances in their research
3. sense_key=report%2:32:03:: | definition=announce one's presence | examples=I report to work every day at 9 o'clock
4. sense_key=report%2:32:01:: | definition=make known to the authorities | examples=One student reported the other to the principal
5. sense_key=report%2:32:13:: | definition=be responsible for reporting the details of, as in journalism | synonyms=cover | examples=Snow reported on China in the 1950's; The cub reporter covered New York City
6. sense_key=report%2:32:02:: | definition=complain about; make a charge against | examples=I reported her to the supervisor

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Usage of "Reported"**

Okay, so I'm looking at the word "reported" in this sentence about the p53 gene: "Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous." My initial thought is to quickly consider the potential senses, to make sure I grasp the nuance here. I'm seeing a few possibilities, each with subtly different shades of meaning. We've got "to describe" or "account for," "to announce as a finding," "to announce one's presence," "to make known to the authorities," "to be responsible for reporting," and finally "to complain or charge."

Given the context, the primary focus seems to be on the *act* of presenting a new discovery. The researchers aren't just *describing* their work, they're not *complaining* or *announcing their presence*. I'm leaning heavily towards "announce as the result of an investigation or experience or finding." The example provided, "The team reported significant advances in their research," is a perfect parallel. It is a very close match and provides clarity. So, sense 2 is the most appropriate. The researchers have uncovered something and are presenting it. This really cements the correct interpretation, and I can move on, confident in my understanding of the sentence.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: find
Target surface form: finding
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported <t>finding</t> a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=find%2:40:02:: | definition=come upon, as if by accident; meet with | synonyms=happen, chance, bump, encounter | examples=We find this idea in Plato; I happened upon the most wonderful bakery not very far from here
2. sense_key=find%2:39:02:: | definition=discover or determine the existence, presence, or fact of | synonyms=detect, observe, discover, notice | examples=She detected high levels of lead in her drinking water; We found traces of lead in the paint
3. sense_key=find%2:40:00:: | definition=come upon after searching; find the location of something that was missed or lost | synonyms=regain | examples=Did you find your glasses?; I cannot find my gloves!
4. sense_key=find%2:32:00:: | definition=establish after a calculation, investigation, experiment, survey, or study | synonyms=determine, find out, ascertain | examples=find the product of two numbers; The physicist who found the elusive particle won the Nobel Prize
5. sense_key=find%2:31:10:: | definition=come to believe on the basis of emotion, intuitions, or indefinite grounds | synonyms=feel | examples=I feel that he doesn't like me; I find him to be obnoxious
6. sense_key=find%2:39:01:: | definition=perceive or be contemporaneous with | synonyms=witness, see | examples=We found Republicans winning the offices; You'll see a lot of cheating in this school
7. sense_key=find%2:40:01:: | definition=get something or somebody for a specific purpose | synonyms=line up, get hold, come up | examples=I found this gadget that will serve as a bottle opener; I got hold of these tools to fix our plumbing
8. sense_key=find%2:36:00:: | definition=make a discovery, make a new finding | synonyms=discover | examples=Roentgen discovered X-rays; Physicists believe they found a new elementary particle
9. sense_key=find%2:31:09:: | definition=make a discovery | synonyms=discover | examples=She found that he had lied to her; The story is false, so far as I can discover
10. sense_key=find%2:40:03:: | definition=obtain through effort or management | examples=She found the time and energy to take care of her aging parents; We found the money to send our sons to college
11. sense_key=find%2:32:01:: | definition=decide on and make a declaration about | synonyms=rule | examples=find someone guilty
12. sense_key=find%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, obtain, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
13. sense_key=find%2:39:05:: | definition=perceive oneself to be in a certain condition or place | examples=I found myself in a difficult situation; When he woke up, he found himself in a hospital room
14. sense_key=find%2:40:15:: | definition=get or find back; recover the use of | synonyms=recover, retrieve, regain | examples=She regained control of herself; She found her voice and replied quickly
15. sense_key=find%2:38:10:: | definition=succeed in reaching; arrive at | examples=The arrow found its mark
16. sense_key=find%2:30:13:: | definition=accept and make use of one's personality, abilities, and situation | synonyms=find oneself | examples=My son went to Berkeley to find himself

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 8}
```

content:
```json
{"sense_index": 8}
```

reasoning_content:
**Analyzing the Sense of "Finding"**

Alright, let's break this down. The target is the word "finding" in the phrase "researchers reported finding a gene called p53." My initial approach, as always, is to consider the potential senses of "find."

I'm presented with a list of candidates, and my mind immediately starts comparing them. We have "come upon by accident," "detect," "regain," "establish after investigation," and so on. But right away, Sense 8 and Sense 4 stand out. Sense 8, "make a discovery, make a new finding," seems promising, as does Sense 4, which is about establishing something via investigation. However, these two are similar.

The examples are key. Let's compare the examples for those two and look at the WordNet entries. Ah, here's an interesting point: WordNet actually lists "Physicists believe they found a new elementary particle" as an example of *both*! This prompts a closer look at the subtle differences. Is it about discovering something new or is it about establishing an already existing entity?

I delve into the WordNet definitions. Sense 8 defines it as "make a discovery, make a new finding," and Sense 4 focuses on "establish after a calculation, investigation, experiment, survey, or study." Hmm, does the sentence, "researchers reported finding a gene called p53" fall into discovery or establishing the entity?

The key lies in the context. The surrounding text mentions a "discovery" explicitly and references another discovery. This points clearly towards a novel finding of an entity which is analogous to a new particle or X-rays.

So, when I consider the sentence "researchers reported finding a gene called p53," the most accurate sense is clearly Sense 8, which is: "make a discovery, make a new finding". "Finding a gene" is equivalent to "discovering a gene." This is a discovery of a novel entity in science.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: call
Target surface form: called
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene <t>called</t> p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=call%2:32:02:: | definition=assign a specified (usually proper) proper name to | synonyms=name | examples=They named their son David; The new school was named after the famous Civil Rights leader
2. sense_key=call%2:32:00:: | definition=ascribe a quality to or give a name of a common noun that reflects a quality | examples=He called me a bastard; She called her children lazy and ungrateful
3. sense_key=call%2:32:01:: | definition=get or try to get into communication (with someone) by telephone | synonyms=telephone, call up, phone, ring | examples=I tried to call you all night; Take two aspirin and call me in the morning
4. sense_key=call%2:32:09:: | definition=utter a sudden loud cry | synonyms=shout, shout out, cry, yell, scream, holler | examples=she cried with pain when the doctor inserted the needle; I yelled to her from the window but she couldn't hear me
5. sense_key=call%2:32:05:: | definition=order, request, or command to come | synonyms=send for | examples=She was called into the director's office; Call the police!
6. sense_key=call%2:41:00:: | definition=pay a brief visit | synonyms=visit, call in | examples=The mayor likes to call on some of the prominent citizens
7. sense_key=call%2:41:04:: | definition=call a meeting; invite or command to meet | examples=The Wannsee Conference was called to discuss the `Final Solution'; The new dean calls meetings every week
8. sense_key=call%2:32:13:: | definition=read aloud to check for omissions or absentees | examples=Call roll
9. sense_key=call%2:32:04:: | definition=send a message or attempt to reach someone by radio, phone, etc.; make a signal to in order to transmit a message | examples=Hawaii is calling!; A transmitter in Samoa was heard calling
10. sense_key=call%2:32:03:: | definition=utter a characteristic note or cry | examples=bluejays called to one another
11. sense_key=call%2:42:09:: | definition=stop or postpone because of adverse conditions, such as bad weather | examples=call a football game
12. sense_key=call%2:41:14:: | definition=greet, as with a prescribed form, title, or name | synonyms=address | examples=He always addresses me with `Sir'; Call me Mister
13. sense_key=call%2:41:12:: | definition=make a stop in a harbour | examples=The ship will call in Honolulu tomorrow
14. sense_key=call%2:40:09:: | definition=demand payment of (a loan) | synonyms=call in | examples=Call a loan
15. sense_key=call%2:40:05:: | definition=make a demand, as for a card or a suit or a show of hands | synonyms=bid | examples=He called his trump
16. sense_key=call%2:38:00:: | definition=give the calls (to the dancers) for a square dance | synonyms=call off
17. sense_key=call%2:32:06:: | definition=indicate a decision in regard to | examples=call balls and strikes behind the plate
18. sense_key=call%2:32:10:: | definition=make a prediction about; tell in advance | synonyms=predict, foretell, prognosticate, forebode, anticipate, promise | examples=Call the outcome of an election
19. sense_key=call%2:32:12:: | definition=require the presentation of for redemption before maturation | examples=Call a bond
20. sense_key=call%2:32:07:: | definition=challenge (somebody) to make good on a statement; charge with or censure for an offense | examples=He deserves to be called on that
21. sense_key=call%2:32:08:: | definition=declare in the capacity of an umpire or referee | examples=call a runner out
22. sense_key=call%2:32:11:: | definition=lure by imitating the characteristic call of an animal | examples=Call ducks
23. sense_key=call%2:32:15:: | definition=order or request or give a command for | examples=The unions called a general strike for Sunday
24. sense_key=call%2:32:14:: | definition=order, summon, or request for a specific duty or activity, work, role | examples=He was already called 4 times for jury duty; They called him to active military duty
25. sense_key=call%2:31:13:: | definition=utter in a loud voice or announce | examples=He called my name; The auctioneer called the bids
26. sense_key=call%2:31:00:: | definition=challenge the sincerity or truthfulness of | examples=call the speaker on a question of fact
27. sense_key=call%2:31:05:: | definition=consider or regard as being | examples=I would not call her beautiful
28. sense_key=call%2:29:05:: | definition=rouse somebody from sleep with a call | examples=I was called at 5 A.M. this morning

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Meaning of "Called" in Context**

Okay, so we've got this sentence: "researchers reported finding a gene called p53..." My focus here is on the word "called". Let's dissect this using the definitions. The goal is pinpointing the exact meaning of "called" in this context.

It's clear, based on the definitions provided, that "called" isn't being used in the sense of assigning a quality or considering the gene to be something, which would be sense 2 or 27. Those don't fit at all. There's no implication of ascribing a quality or regarding the gene as something in this statement.

Instead, the phrase "a gene called p53" clearly indicates that "p53" is the proper name, the designation, the label assigned to this gene. This is a straightforward case of nomenclature. The researchers found a gene and they *named* it "p53". Therefore, I'm confident that the intended meaning corresponds directly to sense 1: assigning a proper name. This is a clear and simple instance of the definition that encompasses the concept of assigning a specified (usually proper) proper name to, or naming. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: impair
Target surface form: impaired
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if <t>impaired</t>, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=impair%2:30:00:: | definition=make worse or less effective | examples=His vision was impaired
2. sense_key=impair%2:30:01:: | definition=make imperfect | synonyms=mar, spoil, deflower, vitiate | examples=nothing marred her beauty

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Meaning of "Impaired" in a Biological Context**

Okay, so I'm looking at this use of "impaired" in relation to the p53 gene and its role in cancer development. My initial thought process is to consider the possible senses of "impaired." I have two main candidates from my WordNet knowledge.

Sense 1: "make worse or less effective." This seems to fit, especially when we're talking about a gene's function. The example "His vision was impaired" immediately brings to mind a functional deficit.

Sense 2: "make imperfect," with synonyms like "mar," "spoil," etc. This suggests a deviation from an ideal state, which *could* work, but it leans more toward aesthetics or a sort of corrupted "purity," which isn't the primary focus here.

The key is that the context describes the gene being "damaged" and leading to cancerous transformation. This suggests a loss of function. If the p53 gene is "impaired," it directly causes healthy cells to become cancerous. That's a clear indication of a diminished capability – making the gene "less effective" at its job. The text explicitly says it is "damaged." So, "make worse or less effective" really clicks with what's happening.

I’m now verifying this using WordNet. Looking at examples in WordNet gives greater clarity. Comparing "His vision was impaired" (functional impairment) with "nothing marred her beauty" (aesthetic imperfection) solidifies my choice. Clearly, in this scenario, where a gene's normal function is disrupted, Sense 1 – "make worse or less effective" – is far more accurate and pertinent. This is a clear case of functional impairment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: turn
Target surface form: turns
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, <t>turns</t> healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=turn%2:38:00:: | definition=change orientation or direction, also in the abstract sense | examples=Turn towards me; The mugger turned and fled before I could see his face
2. sense_key=turn%2:30:04:: | definition=undergo a transformation or a change of position or action | synonyms=change state | examples=We turned from Socialism to Capitalism; The people turned against the President when he stole the election
3. sense_key=turn%2:42:00:: | definition=undergo a change or development | synonyms=become | examples=The water turned into ice; Her former friend became her worst enemy
4. sense_key=turn%2:38:02:: | definition=cause to move around or rotate | examples=turn a key; turn your palm this way
5. sense_key=turn%2:30:00:: | definition=change to the contrary | synonyms=change by reversal, reverse | examples=The trend was reversed; the tides turned against him
6. sense_key=turn%2:38:03:: | definition=pass to the other side of | synonyms=move around | examples=turn the corner; move around the obstacle
7. sense_key=turn%2:30:03:: | definition=pass into a condition gradually, take on a specific property or attribute; become | synonyms=grow | examples=The weather turned nasty; She grew angry
8. sense_key=turn%2:35:08:: | definition=let (something) fall or spill from a container | synonyms=release | examples=turn the flour onto a plate
9. sense_key=turn%2:38:04:: | definition=move around an axis or a center | examples=The wheels are turning
10. sense_key=turn%2:38:01:: | definition=cause to move around a center so as to show another side of | synonyms=turn over | examples=turn a page of a book
11. sense_key=turn%2:38:06:: | definition=to send or let go | examples=They turned away the crowd at the gate of the governor's mansion
12. sense_key=turn%2:36:00:: | definition=to break and turn over earth especially with a plow | synonyms=plow, plough | examples=Farmer Jones plowed his east field last week; turn the earth in the Spring
13. sense_key=turn%2:35:06:: | definition=shape by rotating on a lathe or cutting device or a wheel | examples=turn the legs of the table; turn the clay on the wheel
14. sense_key=turn%2:30:09:: | definition=change color | examples=In Vermont, the leaves turn early
15. sense_key=turn%2:29:00:: | definition=twist suddenly so as to sprain | synonyms=twist, sprain, wrench, wrick, rick | examples=wrench one's ankle; The wrestler twisted his shoulder
16. sense_key=turn%2:42:13:: | definition=cause to change or turn into something different;assume new characteristics | examples=The princess turned the frog into a prince by kissing him; The alchemists tried to turn lead into gold
17. sense_key=turn%2:41:10:: | definition=accomplish by rotating | examples=turn a somersault; turn cartwheels
18. sense_key=turn%2:40:13:: | definition=get by buying and selling | examples=the company turned a good profit after a year
19. sense_key=turn%2:38:13:: | definition=cause to move along an axis or into a new direction | examples=turn your face to the wall; turn the car around
20. sense_key=turn%2:38:14:: | definition=channel one's attention, interest, thought, or attention toward or away from something | examples=The pedophile turned to boys for satisfaction; people turn to mysticism at the turn of a millennium
21. sense_key=turn%2:35:11:: | definition=cause (a plastic object) to assume a crooked or angular form | synonyms=flex, bend, deform, twist | examples=bend the rod; twist the dough into a braid
22. sense_key=turn%2:35:10:: | definition=alter the functioning or setting of | examples=turn the dial to 10; turn the heat down
23. sense_key=turn%2:33:13:: | definition=direct at someone | examples=She turned a smile on me; They turned their flashlights on the car
24. sense_key=turn%2:32:14:: | definition=have recourse to or make an appeal or request for help or information to | synonyms=call on | examples=She called on her Representative to help her; She turned to her relatives for help
25. sense_key=turn%2:30:01:: | definition=go sour or spoil | synonyms=sour, ferment, work | examples=The milk has soured; The wine worked
26. sense_key=turn%2:30:14:: | definition=become officially one year older | examples=She is turning 50 this year

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 16}
```

content:
```json
{"sense_index": 16}
```

reasoning_content:
**Analyzing the Semantic Nuances of "Turns"**

Okay, so the target is "turns" in that p53 context. My immediate thought is, alright, this is definitely the transitive/causative "turns" – a gene, if impaired, *causes* something to become something else. The subject is the p53 gene (in its impaired state), the direct object is "healthy colon cells," and "cancerous" is functioning as an object complement, describing the resulting state. Basically, it's causing a transformation.

Now, let's nail down the specific sense. I need to make sure I'm precise. Let me quickly run through the candidates in my mental lexicon. There's sense 16: "cause to change or turn into something different; assume new characteristics." Examples like "the princess turned the frog into a prince," which hits the causative nail right on the head. Then we have sense 7: "pass into a condition gradually; become," that's more intransitive. Sense 3 "undergo a change or development" - also intransitive, and Sense 2: "undergo a transformation or a change of position or action" also an intransitive use.

Right, in this "turns healthy colon cells cancerous" scenario, it's clearly transitive. The gene is the agent, the cells are the patient, and "cancerous" is the resulting attribute. Sense 16 fits like a glove. It’s explicitly about causing a change, about *making* something become something else.  The princess turning the frog, the alchemists turning lead – it’s a direct parallel. That is the winning sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: healthy
Target surface form: healthy
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns <t>healthy</t> colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=healthy%3:00:00:: | definition=having or indicating good health in body or mind; free from infirmity or disease | examples=a rosy healthy baby; staying fit and healthy
2. sense_key=healthy%5:00:00:sound:00 | definition=financially secure and functioning well | examples=a healthy economy
3. sense_key=healthy%5:00:00:wholesome:00 | definition=promoting health; healthful; ; ; ; ; - C.B.Davis | synonyms=salubrious, good for you | examples=a healthy diet; clean healthy air
4. sense_key=healthy%5:00:00:reasonable:00 | definition=exercising or showing good judgment | synonyms=intelligent, levelheaded, sound | examples=healthy scepticism; a healthy fear of rattlesnakes
5. sense_key=healthy%5:00:00:considerable:00 | definition=large in amount or extent or degree | synonyms=goodly, goodish, hefty, respectable, sizable, sizeable | examples=it cost a considerable amount; a goodly amount

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**My Analysis of "Healthy" in Context**

Okay, so the target word is "healthy" within the phrase "...turns healthy colon cells cancerous." My task is to determine the correct sense of "healthy" from the provided options. Let's see what we've got.

The senses offered are: physical well-being, financial stability, promoting health (wholesome), good judgment, and large amount.

Considering "healthy colon cells," it's instantly apparent we're dealing with cellular biology. We're talking about cells transitioning into a cancerous state. Therefore, it's pretty clear that we're referring to cells that are, at the outset, normal, disease-free, and functioning as they should. We're dealing with the literal, biological state of being.

The first sense, "having or indicating good health in body or mind; free from infirmity or disease," is the only one that truly aligns with this context. It's the only definition related to the physical state of the cells. The others are completely irrelevant. Financial security? Judgement? Size? Nope.

So, the best choice is undoubtedly sense 1. The implication of "healthy colon cells" is explicitly that they're free from disease and functioning as they should, which sense 1 captures perfectly. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: colon
Target surface form: colon
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy <t>colon</t> cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=colon%1:08:00:: | definition=the part of the large intestine between the cecum and the rectum; it extracts moisture from food residues before they are excreted
2. sense_key=colon%1:23:01:: | definition=the basic unit of money in El Salvador; equal to 100 centavos | synonyms=El Salvadoran colon
3. sense_key=colon%1:23:00:: | definition=the basic unit of money in Costa Rica; equal to 100 centimos | synonyms=Costa Rican colon
4. sense_key=colon%1:15:00:: | definition=a port city at the Caribbean entrance to the Panama Canal | synonyms=Aspinwall
5. sense_key=colon%1:10:00:: | definition=a punctuation mark (:) used after a word introducing a series or an example or an explanation (or after the salutation of a business letter)

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
Okay, here's my take on those thoughts, framed as my own:

**Analyzing "Colon" in Context**

Alright, the target word is "colon," and the surrounding text mentions "healthy colon cells" turning cancerous. That immediately hones in on a specific meaning, so I'm quickly filtering through potential senses. Let's see... I've got a few candidates:

*   The obvious one – the large intestine, which I'm pretty sure is sense key `colon%1:08:00::`. It's the part that deals with moisture extraction from food residues. This seems spot on, given the "healthy colon cells" bit.
*   Then we have two currencies: the Salvadoran Colón, or `colon%1:23:01::`, and the Costa Rican Colón, `colon%1:23:00::`. Not relevant in any way to the word “cells” or research, so definitely out.
*   There's also a city in Panama, identified as `colon%1:15:00::`. Again, doesn’t make sense in this context.
*   Finally, there's the punctuation mark, `colon%1:10:00::`. Obviously, a punctuation mark has nothing to do with cells or cancer research, so this isn't relevant either.

Given the context of biology and cells, it's irrefutable that sense `colon%1:08:00::` is the correct sense. It's the only one that meshes with the concept of cell health and cancer. This is a pretty straightforward disambiguation.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cells
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon <t>cells</t> cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Identifying the Correct Sense of "Cells"**

Okay, so I need to pinpoint the right meaning of "cells" in this sentence: "Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon <t>cells</t> cancerous." Let's break down the candidate senses I've got. Hmm, a honeycomb cell, that's sense 1. Electric cells, sense 3, are definitely out. Then there are political cadres (sense 4), mobile phones (sense 5), cells for monks/nuns (sense 6), and prison cells (sense 7) - none of those seem relevant. But, "healthy colon cells cancerous"... that screams biology. It has to be the basic unit of living organisms, sense 2! Therefore, sense 2 is the correct one. The index is 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancerous
Target surface form: cancerous
Context:
Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded. "It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells <t>cancerous</t>. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers.

Candidate senses:
1. sense_key=cancerous%5:00:00:malignant:02 | definition=relating to or affected with cancer | examples=a cancerous growth
2. sense_key=cancerous%5:00:00:malign:00 | definition=like a cancer; an evil that grows and spreads | examples=remorse was cancerous within him; pornography is cancerous to the moral development of our children

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Disambiguating "Cancerous" in the Context of Cell Transformation**

Okay, so I need to nail down the precise meaning of "cancerous" in this phrase: "...turns healthy colon cells cancerous." My goal is to determine the correct sense for this word. I've got two candidates to consider. The first, sense_key=cancerous%5:00:00:malignant:02, relates to *being* or *being affected by* cancer. Its definition is pretty straightforward: "relating to or affected with cancer," and the example "a cancerous growth" aligns perfectly with the biological nature of the context.

Then there's the second contender, sense_key=cancerous%5:00:00:malign:00, which defines "cancerous" as something "like a cancer; an evil that grows and spreads." The definition of this sense is more metaphorical. Examples provided, such as "remorse was cancerous within him," highlight an abstract concept rather than a biological process.

Considering the context, which explicitly mentions "healthy colon cells," it's clear we're dealing with a biological transformation, not a metaphor. The phrase is discussing cells that undergo a process that would cause cancer. So, sense 1, the medical sense, is the clear winner here. I'll flag sense 1 (relating to or affected with cancer) as the intended meaning, and the sense index is 1. That's the correct interpretation.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: report
Target surface form: report
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that <t>report</t>, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=report%1:10:03:: | definition=a written document describing the findings of some individual or group | synonyms=study, written report | examples=this accords with the recent study by Hill and Dale
2. sense_key=report%1:10:01:: | definition=the act of informing by verbal report | synonyms=account | examples=he heard reports that they were causing trouble; by all accounts they were a happy couple
3. sense_key=report%1:10:00:: | definition=a short account of the news | synonyms=news report, story, account, write up | examples=the report of his speech; the story was on the 11 o'clock news
4. sense_key=report%1:11:00:: | definition=a sharp explosive sound (especially the sound of a gun firing) | examples=they heard a violent report followed by silence
5. sense_key=report%1:10:04:: | definition=a written evaluation of a student's scholarship and deportment | synonyms=report card | examples=his father signed his report card
6. sense_key=report%1:10:02:: | definition=an essay (especially one written as an assignment) | synonyms=composition, paper, theme | examples=he got an A on his composition
7. sense_key=report%1:09:00:: | definition=the general estimation that the public has for a person | synonyms=reputation | examples=he acquired a reputation as an actor before he started writing; he was a person of bad report

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Deconstructing the Meaning of "Report"**

Alright, let's break this down. The target word is "report" in this sentence: "Soon after that <t>report</t>, two other research teams uncovered evidence..." The context is clear: "researchers reported finding a gene...". So, what kind of "report" are we talking about here? It's a scientific context, and I need to determine the most accurate sense of "report" based on the provided options.

My initial thought is to explore the first sense: "a written document describing the findings of some individual or group." The synonyms "study" and "written report" immediately resonate. Considering the phrase "researchers reported finding a gene," the "report" is likely a published scientific paper or study detailing their findings. The example "this accords with the recent study by Hill and Dale" is perfectly aligned. "Soon after that report" strongly suggests the subsequent research builds upon or reacts to this published work.

But let me consider other options to be absolutely sure. Could it be Sense 3: "a short account of the news"? The passage is from an article, and news reports on scientific findings are common. However, the connection between "researchers reported finding a gene" and "Soon after that report" points more to the *source* of that news, the original scientific study. It makes more sense that this "report" is the study itself, rather than a news story about it, in this specific sentence. In scientific literature and reporting *about* science, the primary "report" would typically be the paper itself.

I'm now confident that Sense 1 is the best fit. It's a "written document describing the findings of some individual or group" – essentially a study or written report. The synonyms "study" and "written report" strengthen this interpretation. The researchers *published* their findings. "Soon after that study" fits perfectly within the scientific context. That's it. It's sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two <t>other</t> research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Usage of "Other"**

Okay, the target word is "other" and it's used in the phrase "two other research teams." Let's break this down. The core of my analysis focuses on selecting the correct sense of the word.

Looking at the candidate senses, the first one, **other%3:00:00::**, seems like the most promising. It describes something *not the same* as what's already been discussed or implied. The example provided solidifies this direction - "not any *other* day". In our case, "two *other* research teams" has to mean two teams *distinct from* the team that just reported their findings.

The other senses are quickly eliminated. Sense 2 and 3, dealing with "recently past" and "distant past" respectively, are clearly irrelevant. Sense 4, which deals with something *unusual*, also doesn't fit the context. The sentence isn't suggesting these are strange or unusual teams. It is a straightforward statement about teams distinct from the first.

Therefore, sense 1 is the clear winner. "Two other research teams" is a simple and clear way of saying there were two teams *in addition* to the previous one, distinct from the initial reporting group.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: team
Target surface form: teams
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research <t>teams</t> uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=team%1:14:00:: | definition=a cooperative unit (especially in sports) | synonyms=squad
2. sense_key=team%1:14:01:: | definition=two or more draft animals that work together to pull something

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Nuances of "Teams"**

Alright, let's break this down. The target word is "teams" – plural, and of course, a core concept in my field. The phrase in question is "two other research teams uncovered evidence". I immediately start sifting through my mental lexicon of possibilities. My first thought is the most common sense of "team": that cooperative unit, especially as we see it in sports, which I'll tag as team%1:14:00::. Then there's the more archaic sense, team%1:14:01::, referencing draft animals.

Given the context of "research teams", it's a no-brainer. We're dealing with a group of researchers working collaboratively. The draft animal sense is obviously irrelevant here. Sense 1, the cooperative unit sense, is the only logical interpretation. Simple enough.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: evidence
Target surface form: evidence
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered <t>evidence</t> that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=evidence%1:09:00:: | definition=your basis for belief or disbelief; knowledge on which to base belief | synonyms=grounds | examples=the evidence that smoking causes lung cancer is very compelling
2. sense_key=evidence%1:10:01:: | definition=an indication that makes something evident | examples=his trembling was evidence of his fear
3. sense_key=evidence%1:10:00:: | definition=(law) all the means by which any alleged matter of fact whose truth is investigated at judicial trial is established or disproved

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Meaning of "Evidence"**

Okay, the target word is "evidence" within this specific sentence about cancer research. Let's see... the sentence is: "Soon after that report, two other research teams uncovered <t>evidence</t> that the same damaged p53 gene is present in tissue from lung and breast cancers."

My initial thought is to consider the different senses this word might have. I've got three options here, and I need to carefully evaluate each one.

Sense 1 defines "evidence" as "your basis for belief or disbelief; knowledge on which to base belief." The synonyms are "grounds," and there's an example: "the evidence that smoking causes lung cancer is very compelling." Hmm, that example is interesting. It directly relates "evidence" to a claim or scientific fact.

Sense 2 gives us "an indication that makes something evident," and the example is "his trembling was evidence of his fear." This feels a bit less precise in this context, but I'll hold on to it for now.

Sense 3 is the legal definition, related to a judicial trial. That's clearly not relevant here.

Now, let's go back to the sentence. The researchers "uncovered *evidence* that the same damaged p53 gene is present..." The crucial phrase is "evidence that [clause]." It suggests that the "evidence" provides the *basis* for the claim that the gene is present. Sense 1 fits this syntax perfectly. It represents the scientific grounds for this claim. The discovery serves as support for belief. Sense 2 feels weaker and more general in this context.

Therefore, my best analysis is that Sense 1 is the most appropriate. It's the most syntactically and semantically accurate fit, describing the scientific basis for the researchers' conclusion.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: same
Target surface form: same
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the <t>same</t> damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=same%3:00:02:: | definition=same in identity | examples=the same man I saw yesterday; never wore the same dress twice
2. sense_key=same%3:00:00:: | definition=closely similar or comparable in kind or quality or quantity or degree | examples=curtains the same color as the walls; two girls of the same age
3. sense_key=same%3:00:04:: | definition=equal in amount or value | synonyms=like | examples=like amounts; equivalent amounts
4. sense_key=same%5:00:00:unchanged:00 | definition=unchanged in character or nature | examples=the village stayed the same; his attitude is the same as ever

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Meaning of "Same" in a Scientific Context**

Okay, so I'm presented with this sentence: "Soon after that report, two other research teams uncovered evidence that the *same* damaged p53 gene is present in tissue from lung and breast cancers." My mind immediately goes to the word "same," and I need to be precise. In my field, accuracy is everything.

I start by considering the possible senses of "same". I've got a few options: *same in identity*, *closely similar*, *equal in amount*, or *unchanged*. My initial gut tells me it's not simply "similar." It's almost certainly not "equal in amount," or "unchanged." The important distinction is between "the exact same entity" versus "a similar entity."

I see two potentially applicable senses and focus on those. I start to weigh sense 1 against sense 2. Is it the *same* gene, identically, or just *a* similar gene?

The key phrase is "the *same* damaged p53 gene". Given the context of a specific gene, I start to lean towards identity. I've got to consider this carefully: "the same damaged p53 gene" Is it a single distinct gene or just another, similar one? That word "the" is critical here: "the same [type of] gene", or identical token? The phrase "the same [type of] gene" or identical entity?

I recall the examples: "the same man I saw yesterday" vs "the same color". The way the word is used in English is important. "The same man" refers to an individual I've identified previously. "The same color" suggests a comparable characteristic, a quality, not a concrete entity.

I circle back to sense 1 and its key phrases: "the same man I saw yesterday" or "never wore the same dress twice." That's the one! It's about *identity*. This is a match for the situation. It's not just *a* similar gene, it is the *identical* gene.

Therefore, sense 1 is definitely the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: damaged
Target surface form: damaged
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same <t>damaged</t> p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=damaged%3:00:00:: | definition=harmed or injured or spoiled | examples=I won't buy damaged goods; the storm left a wake of badly damaged buildings
2. sense_key=damaged%5:00:00:disreputable:00 | definition=being unjustly brought into disrepute | synonyms=discredited | examples=a discredited politician; her damaged reputation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
Here's my analysis of the word "damaged" in this context:

**Determining the Appropriate Sense Index**

Okay, so I need to figure out the best sense index for "damaged" in this phrase: "damaged p53 gene." The task is straightforward, but I have to be precise. The system gives me two options. Let's break them down.

Sense 1: "harmed or injured or spoiled." This definition immediately resonates with the biological context. A "damaged gene" implies that it's dysfunctional or has undergone some kind of detrimental change that impairs its normal function. The examples provided—"damaged goods," "damaged buildings"—further support this interpretation of impairment or defect. This aligns perfectly with the idea of a mutated or malfunctioning gene.

Sense 2: "being unjustly brought into disrepute," which is synonymous with "discredited." This definition relates to reputation or credibility. It doesn't fit the biological context at all. A gene isn't a person or entity that can be "discredited." The context is about biological harm.

Therefore, sense 1 is clearly the correct choice. The "damaged p53 gene" is referring to a gene that is impaired, harmed, or mutated, not one whose reputation has been sullied. The definition associated with sense 1 fits better in this instance.

The required output is: `{"sense_index": 1}`


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: present
Target surface form: present
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is <t>present</t> in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=present%3:00:01:: | definition=temporal sense; intermediate between past and future; now existing or happening or in consideration | examples=the present leader; articles for present use
2. sense_key=present%3:00:02:: | definition=being or existing in a specified place | examples=the murderer is present in this room; present at the wedding

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
Here's my thought process, distilled:

**Analyzing "Present" in Context**

Okay, the target word is "present," and it's used in the sentence about the p53 gene. My initial step is to identify the possible senses. We've got two contenders: the temporal sense (now, current) and the locative sense (being in a place). Given the context – “…evidence that the same damaged p53 gene is present in tissue…” – the temporal meaning just doesn't fit. We're not talking about something happening *now*, but rather something *existing* in a particular location. Therefore, the locative meaning ("being or existing in a specified place") is the only viable interpretation. So, it's clear that present%3:00:02:: is the correct sense to use here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: tissue
Target surface form: tissue
Context:
"It turns out that studying a tragic but uncommon tumor made possible some fundamental insights about the most basic workings of cancer, "says Samuel Broder, director of the National Cancer Institute. "All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in <t>tissue</t> from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year.

Candidate senses:
1. sense_key=tissue%1:08:00:: | definition=part of an organism consisting of an aggregate of cells having a similar structure and function
2. sense_key=tissue%1:27:02:: | definition=a soft thin (usually translucent) paper | synonyms=tissue paper

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Semantic Landscape of "Tissue"**

Okay, so the task is clear: I need to pinpoint the intended meaning of "tissue" in that specific sentence about p53 genes. My brain immediately starts sifting through the potential senses. I've got two primary contenders: the biological "tissue" – that organized collection of cells with a shared function – and, of course, the paper-based "tissue."

Given the context – we're talking about lung and breast *cancers* and a damaged gene being *present* within it – the biological definition is, without a doubt, the correct one. The idea of paper tissue doesn't even enter the realm of possibility here. It's a slam dunk. So, that's candidate sense number one – the biological tissue – that's the winner.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: most
Target surface form: most
Context:
"All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the <t>most</t> common and lethal forms of the disease, collectively killing almost 200,000 Americans a year. Right now about a dozen laboratories, in the U.S., Canada and Britain, are racing to unmask other suspected tumor-suppressing genes.

Candidate senses:
1. sense_key=most%4:02:00:: | definition=used to form the superlative | synonyms=to the highest degree | examples=the king cobra is the most dangerous snake
2. sense_key=most%4:02:01:: | definition=very | examples=a most welcome relief
3. sense_key=most%4:02:02:: | definition=(of actions or states) slightly short of or not quite accomplished; all but | synonyms=about, almost, nearly, near, nigh, virtually | examples=the job is (just) about done; the baby was almost asleep when the alarm sounded

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Nuances of "Most" in Cancer Mortality Statistics**

Okay, so I'm looking at the word "most" in this sentence: "Colon, lung and breast cancers are the *most* common and lethal forms of the disease..." My immediate thought is, which sense of "most" are we dealing with here? Let's break it down.

First, I consider the possible senses: the superlative, like "the *most* dangerous," a general intensifier, like "a *most* welcome relief," or something implying near completion, such as "almost" or "nearly."

Given the context – "the *most* common and lethal forms" – the superlative sense is the only logical choice. We're not saying the cancers are "very" common and lethal (that would be sense 2), nor are we implying they're *almost* common and lethal (that's sense 3). The phrase uses the structure "the + most + [adjective]," which is a classic superlative. The word is clearly used to indicate the highest degree of commonality and lethality.

So, the appropriate sense here is definitely the first one, represented by the sense key `most%4:02:00::`. It's used to form the superlative. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: common
Target surface form: common
Context:
"All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most <t>common</t> and lethal forms of the disease, collectively killing almost 200,000 Americans a year. Right now about a dozen laboratories, in the U.S., Canada and Britain, are racing to unmask other suspected tumor-suppressing genes.

Candidate senses:
1. sense_key=common%3:00:02:: | definition=belonging to or participated in by a community as a whole; public | examples=for the common good; common lands are set aside for use by all members of a community
2. sense_key=common%3:00:01:: | definition=having no special distinction or quality; widely known or commonly encountered; average or ordinary or usual | examples=the common man; a common sailor
3. sense_key=common%5:00:00:shared:00 | definition=common to or shared by two or more parties | synonyms=mutual | examples=a common friend; the mutual interests of management and labor
4. sense_key=common%5:00:00:familiar:02 | definition=commonly encountered | synonyms=usual | examples=a common (or familiar) complaint; the usual greeting
5. sense_key=common%5:00:00:informal:02 | definition=being or characteristic of or appropriate to everyday language | synonyms=vernacular, vulgar | examples=common parlance; a vernacular term
6. sense_key=common%5:00:00:lowborn:00 | definition=of or associated with the great masses of people | synonyms=plebeian, vulgar, unwashed | examples=the common people in those days suffered greatly; behavior that branded him as common
7. sense_key=common%5:00:00:inferior:02 | definition=of low or inferior quality or value; - Shakespeare | synonyms=coarse | examples=of what coarse metal ye are molded; produced...the common cloths used by the poorer population
8. sense_key=common%5:00:00:unrefined:01 | definition=lacking refinement or cultivation or taste | synonyms=coarse, rough-cut, uncouth, vulgar | examples=he had coarse manners but a first-rate mind; behavior that branded him as common
9. sense_key=common%5:00:00:ordinary:00 | definition=to be expected; standard | examples=common decency

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
**Analyzing the Sense of "Common" in a Medical Context**

Okay, so I'm presented with the word "common" in the phrase "most common and lethal forms of the disease." My task is to pin down the best sense index for "common" in this sentence, and I have a list of candidate senses to work from. Let's see...

I start by considering sense 4: "commonly encountered." The definition and example, "a common (or familiar) complaint," immediately grabs my attention. In a medical context, "complaint" can absolutely mean an ailment or condition. So, "a common complaint" = a widespread illness. This seems promising.

Next, I look at sense 2: "having no special distinction or quality; widely known or commonly encountered; average or ordinary or usual." The examples here, "the common man; a common sailor," point towards "common" as in "not exceptional" or "ordinary." The "average" or "usual" aspects do align with common, but I need to make a firm decision.

WordNet distinguishes between "common#a#1" (belonging to a community) and "common#a#2" (having no special distinction or quality). So, I return to common%5:00:00:familiar:02.

I dig a little deeper. I remind myself of the synset for familiar, that it means "well known or easily recognized" and also: "common, usual ('commonly encountered')." This reinforces the relevance of "commonly encountered." I also double-check, but find that WordNet doesn't have a direct "frequent" satellite under common.

Now I have a clearer picture. "The most common forms of the disease" directly translates to the *most commonly encountered* forms. A disease is common when it is found often in the population.

Focusing on the definition and examples, sense 4's "commonly encountered" and "a common complaint" seems like a direct hit. I remind myself that "complaint" in English can absolutely refer to a medical disorder or illness.

Returning to sense 2: "having no special distinction or quality; widely known or commonly encountered; average or ordinary or usual." Examples include "the common man," "a common sailor," which emphasizes average, not exceptional.

In this medical context, it's clear: "most common and lethal forms of the disease" directly means that those forms are *most commonly encountered* in the population. So, sense 4, common%5:00:00:familiar:02, is the correct and most specific sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: form
Target surface form: forms
Context:
"All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal <t>forms</t> of the disease, collectively killing almost 200,000 Americans a year. Right now about a dozen laboratories, in the U.S., Canada and Britain, are racing to unmask other suspected tumor-suppressing genes.

Candidate senses:
1. sense_key=form%1:10:00:: | definition=the phonological or orthographic sound or appearance of a word that can be used to describe or identify something | synonyms=word form, signifier, descriptor | examples=the inflected forms of a word can be represented by a stem and a list of inflections to be attached
2. sense_key=form%1:09:01:: | definition=a category of things distinguished by some common characteristic or quality | synonyms=kind, sort, variety | examples=sculpture is a form of art; what kinds of desserts are there?
3. sense_key=form%1:09:00:: | definition=a perceptual structure | synonyms=shape, pattern | examples=the composition presents problems for students of musical form; a visual pattern must include not only objects but the spaces between them
4. sense_key=form%1:07:01:: | definition=any spatial attributes (especially as defined by outline) | synonyms=shape, configuration, contour, conformation | examples=he could barely make out their shapes
5. sense_key=form%1:08:00:: | definition=alternative names for the body of a human being | synonyms=human body, physical body, material body, soma, build, figure | examples=Leonardo studied the human body; he has a strong physique
6. sense_key=form%1:03:00:: | definition=the spatial arrangement of something as distinct from its substance | synonyms=shape | examples=geometry is the mathematical science of shape
7. sense_key=form%1:07:00:: | definition=the visual appearance of something or someone | synonyms=shape, cast | examples=the delicate cast of his features
8. sense_key=form%1:10:01:: | definition=a printed document with spaces in which to write | examples=he filled out his tax form
9. sense_key=form%1:14:02:: | definition=(biology) a group of organisms within a species that differ in trivial ways from similar groups | synonyms=variant, strain, var. | examples=a new strain of microorganisms
10. sense_key=form%1:10:02:: | definition=an arrangement of the elements in a composition or discourse | examples=the essay was in the form of a dialogue; he first sketches the plot in outline form
11. sense_key=form%1:07:03:: | definition=a particular mode in which something is manifested | examples=his resentment took the form of extreme hostility
12. sense_key=form%1:26:00:: | definition=(physical chemistry) a distinct state of matter in a system; matter that is identical in chemical composition and physical state and separated from other material by the phase boundary | synonyms=phase | examples=the reaction occurs in the liquid phase of the system
13. sense_key=form%1:14:00:: | definition=a body of students who are taught together | synonyms=class, grade, course | examples=early morning classes are always sleepy
14. sense_key=form%1:07:02:: | definition=an ability to perform well | examples=he was at the top of his form; the team was off form last night
15. sense_key=form%1:06:00:: | definition=a life-size dummy used to display clothes | synonyms=mannequin, manikin, mannikin, manakin
16. sense_key=form%1:06:01:: | definition=a mold for setting concrete | examples=they built elaborate forms for pouring the foundation

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Usage of "Forms"**

Okay, the target word here is "forms" in that cancer sentence. It's clearly about different manifestations of the disease, so the relevant context is "forms of the disease." My immediate thought is to check the various senses of "forms" to ensure the correct one is being used.

Let's see. Sense 2 sounds promising: a "category of things distinguished by some common characteristic or quality." The synonyms listed – kind, sort, variety – immediately resonate. The example provided ("sculpture is a form of art") solidifies that this could be a good fit.

Moving on, sense 11, "a particular mode in which something is manifested," could also be a consideration but seems less directly applicable in this context. It suggests a way something expresses itself, like "his resentment took the form of hostility." I feel that isn't as relevant to describing *types* of cancer.

Finally, Sense 9, "(biology) a group of organisms within a species that differ in trivial ways from similar groups," is clearly wrong. Cancer isn't a group of organisms *within* a species; it's a disease. I can quickly rule that out.

So, I'm confident. Sense 2 it is. "Colon, lung and breast cancers are the most common and lethal forms [kinds, varieties] of the disease" – the word clearly refers to "kind, sort, variety". It's a perfect match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: kill
Target surface form: killing
Context:
"All this may not be obvious to the public, which is concerned about advances in treatment, but I am convinced this basic research will begin showing results there soon. "To date, scientists have fingered two of these cancer-suppressors. Dr. Dryja made his retinoblastoma discovery in 1986. Then last spring, researchers reported finding a gene called p53 which, if impaired, turns healthy colon cells cancerous. Soon after that report, two other research teams uncovered evidence that the same damaged p53 gene is present in tissue from lung and breast cancers. Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively <t>killing</t> almost 200,000 Americans a year. Right now about a dozen laboratories, in the U.S., Canada and Britain, are racing to unmask other suspected tumor-suppressing genes.

Candidate senses:
1. sense_key=kill%2:35:00:: | definition=cause to die; put to death, usually intentionally or knowingly | examples=This man killed several people when he tried to rob a bank; The farmer killed a pig for the holidays
2. sense_key=kill%2:41:01:: | definition=thwart the passage of | synonyms=shoot down, defeat, vote down, vote out | examples=kill a motion; he shot down the student's proposal
3. sense_key=kill%2:30:08:: | definition=end or extinguish by forceful means | synonyms=stamp out | examples=Stamp out poverty!
4. sense_key=kill%2:42:00:: | definition=be fatal | examples=cigarettes kill; drunken driving kills
5. sense_key=kill%2:39:00:: | definition=be the source of great pain for | examples=These new shoes are killing me!
6. sense_key=kill%2:37:00:: | definition=overwhelm with hilarity, pleasure, or admiration | examples=The comedian was so funny, he was killing me!
7. sense_key=kill%2:35:06:: | definition=hit with so much force as to make a return impossible, in racket games | examples=She killed the ball
8. sense_key=kill%2:35:05:: | definition=hit with great force | examples=He killed the ball
9. sense_key=kill%2:35:02:: | definition=deprive of life | examples=AIDS has killed thousands in Africa
10. sense_key=kill%2:35:01:: | definition=cause the death of, without intention | examples=She was killed in the collision of three cars
11. sense_key=kill%2:34:00:: | definition=drink down entirely | synonyms=toss off, pop, bolt down, belt down, pour down, down | examples=He downed three martinis before dinner; She killed a bottle of brandy that night
12. sense_key=kill%2:30:00:: | definition=mark for deletion, rub off, or erase | synonyms=obliterate, wipe out | examples=kill these lines in the President's speech
13. sense_key=kill%2:30:04:: | definition=tire out completely | examples=The daily stress of her work is killing her
14. sense_key=kill%2:30:03:: | definition=cause to cease operating | examples=kill the engine
15. sense_key=kill%2:30:02:: | definition=destroy a vitally essential quality of or in | examples=Eating artichokes kills the taste of all other foods

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 9}
```

content:
```json
{"sense_index": 9}
```

reasoning_content:
**Analyzing the Semantics of "Kill"**

Okay, so I'm looking at the word "kill" in this context: "Colon, lung and breast cancers are the most common and lethal forms of the disease, collectively killing almost 200,000 Americans a year." My first step is, of course, to consider the possible senses. I've got a whole list here, and it's a good range, from the literal "cause to die" to the more figurative senses like "tire out" or "overwhelm with hilarity". I'm seeing everything from the direct "put to death" to more abstract meanings like "mark for deletion".

I immediately zero in on the definitions, and I'm looking for the best semantic fit. I see that definition 9, "kill%2:35:02:: - deprive of life", jumps out at me, especially with the example provided: "AIDS has killed thousands in Africa". The core concept is, of course, the removal of life. That matches this context. The language used, a disease is "killing" people. I can make a strong argument that sense 9 is the precise, intended meaning here.