[User]
Which numbered sense of "baby" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Either copy can make the proteins needed to control cell growth, so for cancer to arise, both copies must be impaired. A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a <t>baby</t>. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced.

Senses:
1. definition=a very young child (birth to 1 year) who has not yet begun to walk or talk | synonyms=babe, infant | examples=the baby began to cry again; she held the baby in her arms
2. definition=the youngest member of a group (not necessarily young) | examples=the baby of the family; the baby of the Supreme Court
3. definition=an immature childish person | synonyms=child | examples=he remained a child in practical matters as long as he lived; stop being a baby!
4. definition=an unborn child; a human fetus | examples=I felt healthy and very feminine carrying the baby; it was great to feel my baby moving about inside
5. definition=(slang) sometimes used as a term of address for attractive young women | synonyms=babe, sister
6. definition=a very young mammal | examples=baby rabbits
7. definition=a project of personal concern to someone | examples=this project is his baby

reasoning_content:
**Analyzing the Context of "Baby"**

Okay, so I'm looking at this text, and the word "baby" is used in the phrase "...after his mother had suffered the same fate when she was a baby." Right away, I need to pinpoint the correct denotation here. It's crucial for understanding the chronology of events. The phrase clearly indicates the mother experienced the "fate" *after* being born.

My first instinct is to consider the different senses of "baby." I quickly rule out sense 4, "an unborn child," because the phrasing implies she'd already been born and was *in* the world to experience the event. This leaves me with sense 1: "a very young child, from birth to one year old, not yet walking or talking." That’s the most logical fit. It's the most appropriate definition given the context, describing a period after birth when she would be susceptible to this kind of rare tumor. It’s a pretty straightforward disambiguation, all things considered.


attempt_kind: initial

status: success

[User]
Which numbered sense of "isolation" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the <t>isolation</t> of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=a state of separation between persons or groups
2. definition=a feeling of being disliked and alone
3. definition=the act of isolating something; setting something apart from others | synonyms=closing off
4. definition=(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
5. definition=a country's withdrawal from international politics | examples=he opposed a policy of American isolation

finish_reason: stop

role: assistant

reasoning_content:
**My Interpretation of "Isolation" in this Context**

Okay, the key word here is "isolation." Considering the context—specifically, "the isolation of the retinoblastoma tumor-suppressor gene"—my mind immediately goes to the scientific meaning. I know this is about genetics, so my focus is on the act of *separating* or *identifying* that specific gene.

I'm mentally running through the various senses of the word to make sure I'm on the right track. I quickly dismiss the interpersonal interpretations; sense 1 (separation between people) and sense 2 (a feeling of being alone) aren't relevant here. Sense 4, the psychiatric definition, is also a no-go. And while I see potential for applying sense 5 (international politics) somewhere in the future, that doesn't seem to apply in this specific situation.

That leaves sense 3, "the act of isolating something; setting something apart from others." Yep, that's the one. It's about taking that gene and making it distinct, extracting it, and separating it out so that we can study or manipulate it. That is the correct match and the appropriate technical definition for the situation.

type: thinking

service_tier: default

currency: USD


[User]
Which numbered sense of "become" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it <t>became</t> possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=enter or assume a certain state or condition | synonyms=go, get | examples=He became annoyed when he heard the bad news; It must be getting more serious
2. definition=undergo a change or development | synonyms=turn | examples=The water turned into ice; Her former friend became her worst enemy
3. definition=come into existence | examples=What becomes has duration
4. definition=enhance the appearance of | synonyms=suit | examples=Mourning becomes Electra; This behavior doesn't suit you!

reasoning_content:
**Analyzing the Shift in Possibility**

Okay, so the text starts with "...it became possible last January to find out...". My expert brain immediately hones in on that verb: "became." It's not just a word; it's a pivot point. We're looking at a transition, a shift in state. Let's break down those potential senses, shall we?

Sense 1, entering a specific state or condition, feels most apt. Think "He became annoyed." Fits like a glove. The phrase here is about entering a state of "possibility." That feels right. We're not talking about a fundamental change (Sense 2, like turning into something), nor the outright creation of something (Sense 3, coming into existence), and certainly not something superficial like "enhancing the appearance" (Sense 4). Nope, this is squarely about the *state* changing to allow for something new. That nuance is key.


[User]
Which numbered sense of "possible" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became <t>possible</t> last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=capable of happening or existing | examples=a breakthrough may be possible next year; anything is possible
2. definition=existing in possibility | synonyms=potential | examples=a potential problem; possible uses of nuclear power

reasoning_content:
Okay, here's my interpretation of that text, presented as a personal thought process, as requested:

**Deconstructing "Possible" in this Context**

Right, so the text flags the use of "possible" in the phrase "it became possible last January to find out what threat the Quinlan baby faced." My immediate thought is to drill down on that word. The implication, and the nuance I need to grasp here, lies in its specific meaning within the sentence. It's not just a general statement about feasibility, that "anything is possible" in a broad philosophical sense. Instead, it's about *capability*. The sentence states that finding out the threat was *capable of happening* starting last January. It's a shift in circumstance, a change in what was *able* to be done.

I'm making sure I'm not misinterpreting it as "existing in possibility," which would imply the *potential* for finding out the threat has always been there, just not realized. That's not the correct meaning here. The sentence signifies a distinct moment in time when the necessary conditions arose, making the investigation or discovery achievable, perhaps through a technological advancement, a change in regulations, or the availability of new information. It's the practical, "could be done" definition that's key here. This specificity is crucial for understanding the chronological progression of this event.


[User]
Which numbered sense of "last" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible <t>last</t> January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=immediately past | examples=last Thursday; the last chapter we read
2. definition=coming after all others in time or space or degree or being the only one remaining | examples=the last time I saw Paris; the last day of the month
3. definition=occurring at or forming an end or termination | synonyms=concluding, final, terminal | examples=his concluding words came as a surprise; the final chapter
4. definition=most unlikely or unsuitable | examples=the last person we would have suspected; the last man they would have chosen for the job
5. definition=occurring at the time of death | examples=his last words; the last rites
6. definition=conclusive in a process or progression | synonyms=final, net | examples=the final answer; a last resort
7. definition=highest in extent or degree | synonyms=utmost | examples=to the last measure of human endurance; whether they were accomplices in the last degree or a lesser one was...to be determined individually
8. definition=not to be altered or undone | synonyms=final | examples=the judge's decision is final; the arbiter will have the last say
9. definition=lowest in rank or importance | synonyms=last-place, lowest | examples=last prize; in last place

reasoning_content:
**Deconstructing "Last January"**

Okay, so the task at hand is to pinpoint the intended meaning of "last" in "last January." My immediate thought process goes like this: we're dealing with a temporal context. I need to figure out which meaning of "last" fits this situation. My knowledge of semantics allows me to immediately consider the most likely interpretation: does it refer to something immediately prior? Let's try it. "Last January" surely refers to the January just completed. Yep, that seems right. Therefore, sense 1, the meaning of 'immediately past', is the only accurate meaning in this instance.


[User]
Which numbered sense of "find_out" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to <t>find out</t> what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=establish after a calculation, investigation, experiment, survey, or study | synonyms=determine, find, ascertain | examples=find the product of two numbers; The physicist who found the elusive particle won the Nobel Prize
2. definition=get to know or become aware of, usually accidentally | synonyms=learn, hear, get word, get wind, pick up, get a line | examples=I learned that she has two grown-up children; I see that you have been promoted
3. definition=find out, learn, or determine with certainty, usually by making an inquiry or other effort | synonyms=determine, check, see, ascertain, watch, learn | examples=I want to see whether she speaks French; See whether it works
4. definition=trap; especially in an error or in a reprehensible act | synonyms=catch out | examples=He was caught out; She was found out when she tried to cash the stolen checks

reasoning_content:
**Deconstructing the Phrase "Find Out"**

Okay, so the text uses "find out" in the context of a new test revealing a threat. My initial instinct is to go with Sense 3, which is about "learn or determine with certainty, usually by making an inquiry or other effort." That feels right: a test is an effort to learn something definitively.

But hold on, let's not jump to conclusions. Sense 1 in some definitions, includes phrases like "determine, find, ascertain." Since this involves a test, an *investigation* is afoot. I need to be more precise here. I recall, though, that some versions of Sense 1 also include "find out." Is that consistent?

Okay, let's consult WordNet directly. I'm really trying to capture the nuances of the phrase and how it's used. The WordNet definitions are crucial here.

Right. Checking WordNet 3.0 confirms my suspicion. *Here's the breakdown*:

*   **Sense 3:** "determine, check, find out, see, ascertain, watch, learn" (specifically matches "find out, learn, or determine with certainty") - this fits perfectly.
*   **Sense 2:** "learn, hear, get word, get wind, pick up, find out, get a line" (get to know or become aware of, usually accidentally) - this doesn't apply.
*   **Sense 4:** "catch out, find out" (trap; especially in an error or in a reprehensible act) - also doesn't apply.

So, Sense 3 is the core. The phrase "find out" *specifically* maps to Sense 3, which is exactly what's happening. We have a *process of inquiry* in this case, and the use of genetic probes confirms that a focused investigation is being undertaken. The choice is clear: I'll go with Sense 3.


[User]
Which numbered sense of "threat" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what <t>threat</t> the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=something that is a source of danger | synonyms=menace | examples=earthquakes are a constant threat in Japan
2. definition=a warning that something unpleasant is imminent | examples=they were under threat of arrest
3. definition=declaration of an intention or a determination to inflict harm on another | examples=his threat to kill me was quite explicit
4. definition=a person who inspires fear or dread | synonyms=terror, scourge | examples=he was the terror of the neighborhood

reasoning_content:
**Analyzing the "Threat" in this Context**

Okay, so the word "threat" here is used in relation to retinoblastoma, that rare eye cancer. My initial instinct is to hone in on the core meaning, and I'm finding that's the right move. Let's break it down by senses to be sure. First, is it referring to something that is a source of danger? That feels like a good fit, like an earthquake is a constant *menace* in Japan. Second, a warning of something unpleasant? Not quite. Third, is it a declaration of intent to harm? No. Fourth, is it a person who causes fear? Nope.

Yes, sense number one, something that is a source of danger, is the best interpretation. It fits the context; "what threat the Quinlan baby faced". That danger is the cancer itself, the risk of developing it. It's the inherent danger posed by the disease. So, that checks out; this is about the danger or risk. I’m happy with that. I've confirmed that the most appropriate definition is a source of danger.


[User]
Which numbered sense of "baby" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan <t>baby</t> faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=a very young child (birth to 1 year) who has not yet begun to walk or talk | synonyms=babe, infant | examples=the baby began to cry again; she held the baby in her arms
2. definition=the youngest member of a group (not necessarily young) | examples=the baby of the family; the baby of the Supreme Court
3. definition=an immature childish person | synonyms=child | examples=he remained a child in practical matters as long as he lived; stop being a baby!
4. definition=an unborn child; a human fetus | examples=I felt healthy and very feminine carrying the baby; it was great to feel my baby moving about inside
5. definition=(slang) sometimes used as a term of address for attractive young women | synonyms=babe, sister
6. definition=a very young mammal | examples=baby rabbits
7. definition=a project of personal concern to someone | examples=this project is his baby

reasoning_content:
**Analyzing the "Quinlan Baby" Reference**

Okay, so I'm presented with this text discussing a test conducted to assess the risk faced by the "Quinlan baby" due to the retinoblastoma gene. My first instinct is to unpack the context and the meaning of "baby." The text mentions the test's timing – "last January" – and refers to Will Quinlan as "little Will Quinlan" which suggests he's already born. It also says the test was performed even before Bonnie became pregnant in 1987. That helps narrow things down.

I need to nail down the precise meaning of "baby" here. There are a couple of relevant senses: a very young child (birth to 1 year), and an unborn child or fetus. The text's reference to "little Will Quinlan" and the comparison to "other children" strongly pushes me towards Sense 1. This phrasing feels more natural when referring to an infant who has been born. Even if the testing was prenatal, the term "baby" is often used to refer to their infant child as well.

I'm leaning heavily towards Sense 1: a very young child. The way it's used in the passage just feels the most natural fit. Now, let me quickly double-check the definitions. Yes, my initial assessment using wordnet is validated. The "Quinlan baby" reference more likely falls under the first sense – a very young child.


[User]
Which numbered sense of "face" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: A person who is born with one defective copy of a suppressor gene, or in whom one copy is damaged early in life, is especially prone to cancer because he need only lose the other copy for a cancer to develop. Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby <t>faced</t>. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer.

Senses:
1. definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes
2. definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring
3. definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond
4. definition=be opposite | examples=the facing page; the two sofas face each other
5. definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now
6. definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions
7. definition=turn so as to expose the face | examples=face a playing card
8. definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket
9. definition=cover the front or surface of | examples=The building was faced with beautiful stones

reasoning_content:
**Deconstructing the Phrase "The Threat the Baby Faced"**

Okay, so the sentence is "it became possible last January to find out what threat the Quinlan baby <t>faced</t>." My initial read is that "face" here refers to being confronted by something unpleasant, a threat in this case. Let's break down the possible senses to confirm and refine this understanding.

I'm thinking of these senses:
1.  Deal with something unpleasant head-on.
2.  Oppose, as in hostility or competition.
3.  Be oriented in a certain direction.
4.  Be opposite.
5.  Turn so as to face.
6.  Present someone with something.

Now, let's analyze each one in the context of the sentence. Sense 1, "deal with something unpleasant head-on," seems like the most obvious and appropriate fit. For example, "He faced the terrible consequences." Here, the baby is *facing* (dealing with/being confronted by) a threat. Yes, definitely, sense 1 is the correct one.


[User]
Which numbered sense of "use" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test <t>using</t> new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

reasoning_content:
**Deconstructing the Verb "Using"**

Okay, so the word we're dealing with here is "using," specifically in the phrase "A test using new 'genetic probes.'" My immediate thought is that this is about *application* – it's about the probes being *employed* in some way. Let's break this down further and define the senses so we can be precise, especially since precision is key in my field.

I'm thinking:

*   **Sense 1:** *put into service; make work or employ for a particular purpose.* This is it! Synonyms like utilize, apply, and employ are spot-on and fit the scientific context flawlessly. This is about *how* the probes function within the experiment.

*   **Sense 2:** *take or consume drugs.* Definitely not relevant. This is obviously not the correct meaning.

*   **Sense 3:** *use up, consume fully.* This doesn't resonate either. We're likely not talking about the probes being *consumed*, but rather *utilized*.

*   **Sense 4:** *seek or achieve an end by using to one's advantage.* While there might be an "advantage" in using the probes (better results, more efficiency), this sense isn't the primary focus.

*   **Sense 5:** *avail oneself to (practice a religion).* Complete mismatch, irrelevant.

*   **Sense 6:** *habitually do something (used to).* No, this is not a habit.

Therefore, Sense 1 is the unequivocal correct meaning here. It's about employing those genetic probes for the purposes of the experiment; making them work.


[User]
Which numbered sense of "new" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using <t>new</t> "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered | examples=a new law; new cars
2. definition=original and of a kind not seen before | synonyms=fresh, novel | examples=the computer produced a completely novel proof of a well-known theorem
3. definition=lacking training or experience | synonyms=raw | examples=the new men were eager to fight; raw recruits
4. definition=having no previous example or precedent or parallel | synonyms=unexampled | examples=a time of unexampled prosperity
5. definition=other than the former one(s); different | examples=they now have a new leaders; my new car is four years old but has only 15,000 miles on it
6. definition=unaffected by use or exposure | examples=it looks like new
7. definition=(of a new kind or fashion) gratuitously new | synonyms=newfangled | examples=newfangled ideas; she buys all these new-fangled machines and never uses them
8. definition=in use after medieval times | examples=New Eqyptian was the language of the 18th to 21st dynasties
9. definition=used of a living language; being the current stage in its development | synonyms=Modern | examples=Modern English; New Hebrew is Israeli Hebrew
10. definition=(of crops) harvested at an early stage of development; before complete maturity | synonyms=young | examples=new potatoes; young corn
11. definition=unfamiliar | examples=new experiences; experiences new to him

reasoning_content:
**Analyzing the "New" in "New Genetic Probes"**

Okay, so I'm seeing "new" pop up in this context, specifically with "new genetic probes." Immediately, I'm thinking about the implications. The text also mentions "emerging genetic tests" and "new findings" related to the retinoblastoma gene, so the concept of novelty is definitely central here.

My mind is jumping to the different senses of "new." We have the common sense – *recently* come into existence, like a new car or a new law. Then there's the second sense – original, something *novel*. With "new genetic probes", my initial instinct is that it's the first sense. These are probes that have been *recently* developed or discovered.

I'll check WordNet just to be sure. I'm leaning heavily towards the first sense being the more appropriate one, but it's always good to verify. My professional experience tells me that "new genetic probes" are best understood as tools that *just* came into being, not necessarily radically different in kind. They're newly *developed* tools. So yes, Sense 1 it is. The recent development of these tools is the key.


[User]
Which numbered sense of "genetic" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "<t>genetic</t> probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=occurring among members of a family usually by heredity | synonyms=familial, hereditary, inherited, transmitted, transmissible | examples=an inherited disease; familial traits
2. definition=of or relating to or produced by or being a gene | synonyms=genic, genetical | examples=genic combinations; genetic code
3. definition=pertaining to or referring to origin | examples=genetic history reconstructs the origins of a literary work
4. definition=of or relating to the science of genetics | synonyms=genetical | examples=genetic research

reasoning_content:
**Analyzing the Nuance of "Genetic Probes"**

Okay, so the text uses "genetic," specifically in the term "genetic probes." My initial thought, naturally, is that this is related to genes, which makes sense. I need to be precise, though. Let's delve into the different senses of "genetic." Ah, here we go, Sense 2 is key: "of or relating to or produced by or being a gene," with synonyms like "genic" and "genetical," and examples like "genetic code." Sense 4, on the other hand, deals with the broader science, "of or relating to the science of genetics," exemplified by "genetic research."

Aha! A "genetic probe" is, in essence, a tool designed to detect specific gene sequences. Therefore, it's clear: Sense 2 is the most appropriate, as it directly connects the probe to the gene itself. Let's confirm that. "Of or relating to or produced by or being a gene." A "genetic probe" *probes for* a gene – the verb is right there! Yep, Sense 2 is definitely the winner. That makes perfect sense.


[User]
Which numbered sense of "show" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "<t>showed</t> that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=give an exhibition of to an interested audience | synonyms=demo, exhibit, present, demonstrate | examples=She shows her dogs frequently; We will demo the new software in Washington
2. definition=establish the validity of something, as by an example, explanation or experiment | synonyms=prove, demonstrate, establish, shew | examples=The experiment demonstrated the instability of the compound; The mathematician showed the validity of the conjecture
3. definition=provide evidence for | synonyms=testify, bear witness, prove, evidence | examples=The blood test showed that he was the father; Her behavior testified to her incompetence
4. definition=make visible or noticeable | examples=She showed her talent for cooking; Show me your etchings, please
5. definition=show in, or as in, a picture | synonyms=picture, depict, render | examples=This scene depicts country life; the face of the child is rendered with much tenderness in this painting
6. definition=give expression to | synonyms=express, evince | examples=She showed her disappointment
7. definition=indicate a place, direction, person, or thing; either spatially or figuratively | synonyms=indicate, point, designate | examples=I showed the customer the glove section; He pointed to the empty parking space
8. definition=be or become visible or noticeable | synonyms=show up | examples=His good upbringing really shows; The dirty side will show
9. definition=indicate a certain reading; of gauges and instruments | synonyms=read, register, record | examples=The thermometer showed thirteen degrees below zero; The gauge read `empty'
10. definition=give evidence of, as of records | examples=The diary shows his distress that evening
11. definition=take (someone) to their seats, as in theaters or auditoriums | synonyms=usher | examples=The usher showed us to our seats
12. definition=finish third or better in a horse or dog race | examples=he bet $2 on number six to show

reasoning_content:
Here's my analysis of the word "showed" in the provided context, framed as my own thought process:

**Deconstructing "Showed" in a Genetic Context**

Okay, the word "showed" is being used in a precise scientific context: "...a test using new 'genetic probes' showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene..." My immediate thought is, how is this word functioning here? It's key to how the entire sentence communicates an important scientific finding.

The context is crucial; we are talking about a test, specifically one that likely involves genetic analysis. "Showed" here isn't just a casual observation. It signifies that the test results provided empirical evidence, a measurable outcome, which led to a conclusion.

So, I need to check my understanding. It indicates that the test *demonstrated* something, effectively *proved* or *provided evidence* for a conclusion. I can consider the third sense of the definition I am most familiar with as I review this: "provide evidence for" - it is the best match. This is right in line with how we understand this sort of testing within this field. The synonyms confirm this; *testify*, *bear witness*, *prove*, and *evidence* are all perfectly valid in this setting. The example provided, "The blood test showed that he was the father," is directly analogous. It’s a very clean fit with the genetic test scenario described. Therefore, the usage is entirely appropriate and precise.


[User]
Which numbered sense of "little" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that <t>little</t> Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=limited or below average in number or quantity or magnitude or extent | synonyms=small | examples=a little dining room; a little house
2. definition=(quantifier used with mass nouns) small in quantity or degree; not much or almost none or (with `a') at least some | synonyms=slight | examples=little rain fell in May; gave it little thought
3. definition=(of children and animals) young, immature | synonyms=small | examples=what a big little boy you are; small children
4. definition=(informal) small and of little importance | synonyms=fiddling, footling, lilliputian, niggling, piddling, piffling | examples=a fiddling sum of money; a footling gesture
5. definition=(of a voice) faint | synonyms=small | examples=a little voice; a still small voice
6. definition=low in stature; not tall | synonyms=short | examples=he was short and stocky; short in stature
7. definition=lowercase | synonyms=minuscule, small | examples=little a; small a
8. definition=small in a way that arouses feelings (of tenderness or its opposite depending on the context) | examples=a nice little job; bless your little heart

reasoning_content:
Okay, here's my interpretation of that thought process, from an expert's perspective:

**Deconstructing "Little Will Quinlan"**

Alright, let's break this down. The term "little" – specifically in "little Will Quinlan" – immediately flags a specific semantic field. My initial thought process zeroes in on that usage; we're dealing with a young, likely infant or very young child. The phrase is a direct reference to a baby, a minor. My expertise allows me to quickly categorise this under the sense of "little" associated with children, not adults. The primary context here is a state of immaturity or youthfulness. That definition allows me to contextualize the phrase accurately and rapidly.


[User]
Which numbered sense of "inherit" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not <t>inherited</t> a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=obtain from someone after their death | examples=I inherited a castle from my French grandparents
2. definition=receive from a predecessor | examples=The new chairman inherited many problems from the previous chair
3. definition=receive by genetic transmission | examples=I inherited my good eyesight from my mother

reasoning_content:
Here's my understanding of the sentence, framed as my own thought process:

**Decoding Genetic Inheritance in Retinoblastoma**

Okay, I'm parsing this sentence about little Will Quinlan. The key here, and what I'm immediately grasping, is the focus on genetic tests, cancer susceptibility, and specifically, the retinoblastoma tumor-suppressor gene. The language implies that a genetic test, or some form of analysis, has been conducted or is being discussed. The phrase "had not inherited a damaged retinoblastoma suppressor gene" is critical. Given my background, I immediately connect that "inherited" is the crucial term in this instance. Thinking about the various meanings of "inherit," the most relevant here is sense 3, the classic definition: "to receive by genetic transmission". The focus is on the mechanism of inheritance. Therefore, Will *didn't* receive this particular genetic variant. He's in the clear, genetically speaking.


[User]
Which numbered sense of "damaged" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a <t>damaged</t> retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=harmed or injured or spoiled | examples=I won't buy damaged goods; the storm left a wake of badly damaged buildings
2. definition=being unjustly brought into disrepute | synonyms=discredited | examples=a discredited politician; her damaged reputation

reasoning_content:
**Analyzing the Nuances of "Damaged" in a Biological Context**

Okay, so I'm presented with the word "damaged" in the phrase "...damaged retinoblastoma suppressor gene." My immediate task is to nail down the precise meaning within this context. The key lies in understanding the biological implications here. I need to distinguish between the potential senses: "harmed or injured or spoiled" versus "being unjustly brought into disrepute."

Given my expertise, the correct interpretation is unequivocally the first sense. A "damaged gene," in the context of genetics and cellular biology, denotes a gene that has undergone some sort of alteration – a defect, mutation, or spoiling – that impairs its normal function. The idea of a gene's reputation being "discredited" is completely irrelevant here. We're dealing with a tangible biological entity whose structural or functional integrity has been compromised. Therefore, the "damage" refers to a defect within the gene itself. Case closed!


[User]
Which numbered sense of "face" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, <t>faced</t> no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=deal with (something unpleasant) head on | synonyms=confront, face up | examples=You must confront your problems; He faced the terrible consequences of his mistakes
2. definition=oppose, as in hostility or a competition | synonyms=confront | examples=You must confront your opponent; Jackson faced Smith in the boxing ring
3. definition=be oriented in a certain direction, often with respect to another reference point; be opposite to | synonyms=front, look | examples=The house looks north; My backyard look onto the pond
4. definition=be opposite | examples=the facing page; the two sofas face each other
5. definition=turn so as to face; turn the face in a certain direction | examples=Turn and face your partner now
6. definition=present somebody with something, usually to accuse or criticize | synonyms=confront, present | examples=We confronted him with the evidence; He was faced with all the evidence and could no longer deny his actions
7. definition=turn so as to expose the face | examples=face a playing card
8. definition=line the edge (of a garment) with a different material | examples=face the lapels of the jacket
9. definition=cover the front or surface of | examples=The building was faced with beautiful stones

reasoning_content:
**Deconstructing the Word "Faced"**

Okay, so I'm looking at this phrase: "faced no more risk than other children." Immediately, my mind zeroes in on "faced." It's a key word, and its meaning here is crucial for understanding the whole sentence. "Faced," in this context, isn't about physical opposition or being presented with something. My professional brain starts to run through the semantic field, and I see it's about *dealing* with something unpleasant, right? Like, being *confronted* by a situation, a danger, a risk.

Specifically, it leans towards my understanding of Sense 1: dealing with something unpleasant head-on. Consider: "You must *confront* your problems." or "He *faced* the terrible consequences of his mistakes." The baby, in this instance, didn't have to *deal with*, be subjected to, or be *confronted* by any more risk than any other child. That's the core of it. We're talking about direct experience, the baby not *experiencing* the risk, not in the direct experience as mentioned in Sense 1.


[User]
Which numbered sense of "more" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no <t>more</t> risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree | synonyms=more than | examples=more land; more support
2. definition=(comparative of `many' used with count nouns) quantifier meaning greater in number | examples=a hall with more seats; we have no more bananas

reasoning_content:
**Analyzing the Nuance of "More" in Risk Assessment**

Okay, let's break this down. The phrase that caught my attention is "faced no more risk than other children." Immediately, I'm zeroing in on "more." We're dealing with "risk" here, and "risk" in this context is functioning as a mass noun – it's a measure, an extent, a degree of something. It's not countable.

Now, considering the implications of "more" – it can act as a comparative for both "much" (with mass nouns, indicating degree) and "many" (with count nouns, indicating number). But here, it's clear. "No more risk" isn't about counting individual risks; it's about the amount or degree of risk. We're asking whether there is more risk than another child.

Therefore, the first sense – the comparative of "much," pertaining to greater size, amount, extent, or degree – is the correct interpretation. We're not discussing *a greater number* of risks; we're concerned with the *level* of risk. This semantic distinction is critical for accurate risk assessment and interpretation.


[User]
Which numbered sense of "risk" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more <t>risk</t> than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=a source of danger; a possibility of incurring loss or misfortune | synonyms=hazard, jeopardy, peril, endangerment | examples=drinking alcohol is a health hazard
2. definition=a venture undertaken without regard to possible loss or injury | synonyms=peril, danger | examples=he saw the rewards but not the risks of crime; there was a danger he would do the wrong thing
3. definition=the probability of becoming infected given that exposure to an infectious agent has occurred | synonyms=risk of infection
4. definition=the probability of being exposed to an infectious agent | synonyms=risk of exposure

reasoning_content:
**Deconstructing the Concept of Risk**

Okay, so the word is "risk," and the phrase is "faced no more risk than other children of developing the rare cancer." Let's break this down. First, a quick sense check. I need to be sure I'm using the correct definition. My immediate sense is that there are a few possibilities: a source of danger, a possibility of incurring loss or misfortune (that's a hazard or peril, essentially), then perhaps a venture. Hmm, there are also a couple that relate to infection probabilities.

Cancer, obviously, is not infectious, so I can immediately rule out those definitions related to probabilities of infection. That leaves me with the first two. Now, between "a source of danger" and "a venture undertaken without regard to possible loss or injury," it seems pretty clear. "Risk" here means the **possibility of incurring misfortune** – getting cancer. It’s not a deliberate venture, so it cannot be the second meaning. The first definition is the most appropriate. Simple.


[User]
Which numbered sense of "other" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than <t>other</t> children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. definition=recently past | examples=the other evening
3. definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

reasoning_content:
**Analyzing the Nuances of "Other"**

Okay, so I'm dissecting this sentence, "…faced no more risk than other children of developing the rare cancer." My immediate focus is on the word "other." It's crucial for understanding the scope of comparison here, and my brain is already sifting through the possible interpretations.

First, I consider Sense 1: "not the same one or ones already mentioned or implied." Yep, that's the clear winner. "Other" here clearly refers to children *besides* the specific child, Will Quinlan, who was previously mentioned. No ambiguity there.

Then, I quickly dismiss the other senses. Sense 2, "recently past" (like "the other evening")? Completely irrelevant to this context. Sense 3, "belonging to the distant past"? Nope. And Sense 4, "very unusual"? Also a mismatch. "Other" is definitely functioning in a basic comparative sense in this sentence. It is a straightforward use of an ordinal term. This is straightforward semantics, and the nuances are obvious given the text. I am going to move on from this piece, as it is simple.


[User]
Which numbered sense of "child" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other <t>children</t> of developing the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=a young person of either sex | synonyms=kid, youngster, minor, shaver, nipper, small fry | examples=she writes books for children; they're just kids
2. definition=a human offspring (son or daughter) of any age | synonyms=kid | examples=they had three children; they were able to send their kids to college
3. definition=an immature childish person | synonyms=baby | examples=he remained a child in practical matters as long as he lived; stop being a baby!
4. definition=a member of a clan or tribe | examples=the children of Israel

reasoning_content:
**Analyzing the Nuances of "Children" in Context**

Okay, here's what's running through my head as I break down this sentence: "...faced no more risk than other children of developing the rare cancer." My initial thought is that "children" is being used in a broader sense, comparing Will Quinlan (a baby) to other young people in general. I want to make sure I'm precise with my understanding here, so I'm drilling down on the word "children."

I consider the two main senses of the word. Sense 1: a young person of either sex, which feels right. Then Sense 2: a human offspring, son or daughter, of any age. It's that phrase "other children" that's key. It's not about the parent-child relationship *per se*, it's about the age demographic.

"Other children" would clearly translate to "other young people." So, if it’s comparing him to other *young* people, and not explicitly to offspring in a parent-child relationship, Sense 1 seems the stronger fit. It is implying that, but not explicitly.

Let's double-check again. The context supports that it's "other kids" or "other young people" and the word "children" would translate best to "young people" or "kids" in that phrase. No, Sense 1 continues to hold firm.


[User]
Which numbered sense of "develop" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of <t>developing</t> the rare cancer. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=make something new, such as a product or a mental or artistic creation | examples=Her company developed a new kind of building material that withstands all kinds of weather; They developed a new technique
2. definition=work out | synonyms=evolve, germinate | examples=We have developed a new theory of evolution
3. definition=gain through experience | synonyms=acquire, evolve | examples=I acquired a strong aversion to television; Children must develop a sense of right and wrong
4. definition=come to have or undergo a change of (physical features and attributes) | synonyms=grow, produce, get, acquire | examples=He grew a beard; The patient developed abdominal pains
5. definition=come into existence; take on form or shape | synonyms=originate, arise, rise, uprise, spring up, grow | examples=A new religious movement originated in that country; a love that sprang up from friendship
6. definition=change the use of and make available or usable | synonyms=build up | examples=develop land; The country developed its natural resources
7. definition=elaborate, as of theories and hypotheses | synonyms=explicate, formulate | examples=Could you develop the ideas in your thesis
8. definition=create by training and teaching | synonyms=train, prepare, educate | examples=The old master is training world-class violinists; we develop the leaders for the future
9. definition=be gradually disclosed or unfolded; become manifest | examples=The plot developed slowly
10. definition=grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment | examples=A flower developed on the branch; The country developed into a mighty superpower
11. definition=become technologically advanced | synonyms=modernize, modernise | examples=Many countries in Asia are now developing at a very fast pace; Viet Nam is modernizing rapidly
12. definition=cause to grow and differentiate in ways conforming to its natural development | synonyms=make grow | examples=The perfect climate here develops the grain; He developed a new kind of apple
13. definition=generate gradually | examples=We must develop more potential customers; develop a market for the new mobile phone
14. definition=grow emotionally or mature | synonyms=grow | examples=The child developed beautifully in her new kindergarten; When he spent a summer at camp, the boy grew noticeably and no longer showed some of his old adolescent behavior
15. definition=make visible by means of chemical solutions | examples=Please develop this roll of film for me
16. definition=superimpose a three-dimensional surface on a plane without stretching, in geometry
17. definition=move one's pieces into strategically more advantageous positions | examples=Spassky developed quickly
18. definition=move into a strategically more advantageous position | examples=develop the rook
19. definition=elaborate by the unfolding of a musical idea and by the working out of the rhythmic and harmonic changes in the theme | examples=develop the melody and change the key
20. definition=happen | synonyms=break, recrudesce | examples=Report the news as it develops; These political movements recrudesce from time to time
21. definition=expand in the form of a series | examples=Develop the function in the following form

reasoning_content:
**Analyzing the Nuances of "Developing"**

Okay, so the key word here is "developing," specifically in the phrase "developing the rare cancer." My initial instinct is to consider all possibilities. But I need to pinpoint the *specific* meaning within this particular context. It's not about developing a technology or an idea; it's about the cancer itself.

Right, let's break it down. I'm going to consult the definition. The phrase suggests something changing – a physical attribute, a state. Ah, here's Sense 4: "come to have or undergo a change of (physical features and attributes)." That's the one! It's about *acquiring* something, like a physical condition, for example: "The patient developed abdominal pains." Bingo.

Now, let's quickly eliminate the other senses, just to be sure. Sense 3, "gain through experience," doesn't fit the context; it’s more mental or emotional, related to human growth and learning. Sense 5, "come into existence," is intransitive and doesn’t quite match the active sense of acquiring the cancer. So, yes, Sense 4 is definitely the most accurate and precise. The patient is *acquiring* the cancer. This definition is spot on for the phrase “developing the rare cancer.”


[User]
Which numbered sense of "cancer" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Emerging genetic tests will be able to spot such cancer-susceptible individuals, ushering in what some scientists believe is a new age of predictive cancer diagnosis. Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare <t>cancer</t>. "It made our New Year, "says Mr. Quinlan.

Senses:
1. definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. definition=type genus of the family Cancridae | synonyms=genus Cancer

reasoning_content:
**Analyzing the Word "Cancer"**

Okay, the word in question is "cancer." My immediate thought process here is to drill down to the relevant meaning within the provided context. I see references to "retinoblastoma," "tumor," and "damaged gene," along with mention of a higher "risk than other children of developing the rare cancer." This clearly points towards the disease itself. I can immediately disregard the astrological, zodiac, and crab-related senses. That narrows it down considerably. My focus is unequivocally on the first sense: "any malignant growth or tumor caused by abnormal and uncontrolled cell division..." Yes, that's the precise definition that fits this scenario. We are talking about the medical condition.


[User]
Which numbered sense of "make" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It <t>made</t> our New Year, "says Mr. Quinlan. This test was the first to predict reliably whether an individual could expect to develop cancer.

Senses:
1. definition=engage in | synonyms=do | examples=make love, not war; make an effort
2. definition=give certain properties to something | synonyms=get | examples=get someone mad; She made us look silly
3. definition=make or cause to be or to become | synonyms=create | examples=make a mess in one's office; create a furor
4. definition=cause to do; cause to act in a specified manner | synonyms=induce, stimulate, cause, have, get | examples=The ads induced me to buy a VCR; My children finally got me to buy a computer
5. definition=give rise to; cause to happen or occur, not always intentionally | synonyms=cause, do | examples=cause a commotion; make a stir
6. definition=create or manufacture a man-made product | synonyms=produce, create | examples=We produce more cars than we can sell; The company has been making toys for two centuries
7. definition=make, formulate, or derive in the mind | synonyms=draw | examples=I draw a line here; draw a conclusion
8. definition=compel or make somebody or something to act in a certain way | examples=People cannot be made to integrate just by passing a law!; Heat makes you sweat
9. definition=create by artistic means | synonyms=create | examples=create a poem; Schoenberg created twelve-tone music
10. definition=earn on some commercial or business transaction; earn as salary or wages | synonyms=gain, take in, clear, earn, realize, realise | examples=How much do you make a month in your new job?; She earns a lot in her new job
11. definition=create or design, often in a certain way | synonyms=do | examples=Do my room in blue; I did this piece in wood to express my love for the forest
12. definition=to compose or represent: | synonyms=form, constitute | examples=This wall forms the background of the stage setting; The branches made a roof
13. definition=reach a goal, e.g., | synonyms=reach, get to, progress to | examples=make the first team; We made it!
14. definition=be or be capable of being changed or made into | examples=He makes a great host; He will make a fine father
15. definition=make by shaping or bringing together constituents | examples=make a dress; make a cake
16. definition=perform or carry out | examples=make a decision; make a move
17. definition=make by combining materials and parts | synonyms=construct, build | examples=this little pig made his house out of straw; Some eccentric constructed an electric brassiere warmer
18. definition=change from one form into another | examples=make water into wine; make lead into gold
19. definition=act in a certain way so as to acquire | examples=make friends; make enemies
20. definition=charge with a function; charge to be | synonyms=name, nominate | examples=She was named Head of the Committee; She was made president of the club
21. definition=achieve a point or goal | synonyms=have, get | examples=Nicklaus had a 70; The Brazilian team got 4 goals
22. definition=reach a destination, either real or abstract | synonyms=reach, attain, hit, arrive at, gain | examples=We hit Detroit by noon; The water reached the doorstep
23. definition=institute, enact, or establish | synonyms=lay down, establish | examples=make laws
24. definition=carry out or commit | examples=make a mistake; commit a faux-pas
25. definition=form by assembling individuals or constituents | examples=Make a quorum
26. definition=organize or be responsible for | synonyms=hold, throw, have, give | examples=hold a reception; have, throw, or make a party
27. definition=put in order or neaten | synonyms=make up | examples=make the bed; make up a room
28. definition=head into a specified direction | synonyms=take | examples=The escaped convict took to the hills; We made for the mountains
29. definition=have a bowel movement | synonyms=stool, defecate, shit, take a shit, take a crap, ca-ca | examples=The dog had made in the flower beds
30. definition=undergo fabrication or creation | examples=This wool makes into a nice sweater
31. definition=be suitable for | examples=Wood makes good furniture
32. definition=add up to | examples=four and four make eight
33. definition=amount to | examples=This salary increase makes no difference to my standard of living
34. definition=constitute the essence of | examples=Clothes make the man
35. definition=appear to begin an activity | examples=He made to speak but said nothing in the end; She made as if to say hello to us
36. definition=proceed along a path | synonyms=work | examples=work one's way through the crowd; make one's way into the forest
37. definition=reach in time | examples=We barely made the plane
38. definition=gather and light the materials for | examples=make a fire
39. definition=prepare for eating by applying heat | synonyms=cook, fix, ready, prepare | examples=Cook me dinner, please; can you make me an omelette?
40. definition=induce to have sex | synonyms=seduce, score | examples=Harry finally seduced Sally; Did you score last night?
41. definition=assure the success of | examples=A good review by this critic will make your play!
42. definition=represent fictitiously, as in a play, or pretend to be or act like | synonyms=pretend, make believe | examples=She makes like an actress
43. definition=consider as being | examples=It wasn't the problem some people made it
44. definition=calculate as being | examples=I make the height about 100 feet
45. definition=cause to be enjoyable or pleasurable | examples=make my day
46. definition=favor the development of | examples=Practice makes the winner
47. definition=develop into | examples=He will make a splendid father!
48. definition=behave in a certain way | examples=make merry
49. definition=eliminate urine | synonyms=urinate, piddle, puddle, micturate, piss, pee | examples=Again, the cat had made on the expensive rug

reasoning_content:
**Analyzing the Etymology of "Made"**

Alright, let's break this down. The core of understanding this usage of "made" lies in its origin: "It made our New Year." This isn't just about creation; it's about the causative aspect – the thing *caused* our New Year to be enjoyable, successful, a pleasurable experience. It's essentially an assurance of its success.

Focusing on the definition, I'm going through my mental lexicon. Let's see... a definition that aligns perfectly is: "cause to be enjoyable or pleasurable." And the examples seal the deal: "make my day." Bingo. "It made our New Year" is precisely analogous to "make my day." The semantics are spot-on. We are looking at a clear demonstration of the causal link between the subject and the positive emotional response. It's a textbook case.


[User]
Which numbered sense of "say" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: Bill and Bonnie Quinlan are among the first beneficiaries of the new findings. The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "<t>says</t> Mr. Quinlan. This test was the first to predict reliably whether an individual could expect to develop cancer.

Senses:
1. definition=express in words | synonyms=state, tell | examples=He said that he wanted to marry her; tell me what is bothering you
2. definition=report or maintain | synonyms=allege, aver | examples=He alleged that he was the victim of a crime; He said it was too late to intervene in the war
3. definition=express a supposition | synonyms=suppose | examples=Let us say that he did not tell the truth; Let's say you had a lot of money--what would you do?
4. definition=have or contain a certain wording or form | synonyms=read | examples=The passage reads as follows; What does the law say?
5. definition=give instructions to or direct somebody to do something with authority | synonyms=order, tell, enjoin | examples=I said to him to go home; She ordered him to do the shopping
6. definition=speak, pronounce, or utter in a certain way | synonyms=pronounce, articulate, enounce, sound out, enunciate | examples=She pronounces French words in a funny way; I cannot say `zip wire'
7. definition=communicate or express nonverbally | examples=What does this painting say?; Did his face say anything about how he felt?
8. definition=utter aloud | examples=She said `Hello' to everyone in the office
9. definition=state as one's opinion or judgement; declare | examples=I say let's forget this whole business
10. definition=recite or repeat a fixed text | examples=Say grace; She said her `Hail Mary'
11. definition=indicate | examples=The clock says noon

reasoning_content:
**Analyzing the Verb "Says" in a Quotation**

Okay, so I'm looking at the sentence: "'It made our New Year,' says Mr. Quinlan." My initial instinct is that "says" here is simply a speech tag, meaning Mr. Quinlan is "expressing in words" that sentiment. That's usually the go-to meaning in these contexts, a basic way of introducing a direct quote. Let me double-check my assumptions. I need to make sure I'm not missing a nuance, even though it seems straightforward.

I quickly check the possible senses of "says," mentally running through the options. There's "express in words" (Sense 1), which fits perfectly. I could consider "utter aloud" (Sense 8), but that's less precise. Often, when quoting, we're focusing on the *content* of what's said, not just the act of speaking.

Let me verify this against a more authoritative source. Ah, yes, WordNet confirms it: Sense 1 is indeed "express in words." WordNet is fairly comprehensive in this regard. So I quickly review WordNet's senses: it's not "report or maintain", not "express a supposition", not "have or contain a certain wording", or "give instructions". It's not "speak, pronounce", not "communicate nonverbally", not "utter aloud", not "state as one's opinion", not "recite", or "indicate". It's pretty conclusive: "express in words" is the most applicable definition. The context makes it clear. So, yes, it's definitely Sense 1. This is a clear-cut case.


[User]
Which numbered sense of "first" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan. This test was the <t>first</t> to predict reliably whether an individual could expect to develop cancer. Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded.

Senses:
1. definition=preceding all others in time or space or degree | examples=the first house on the right; the first day of spring
2. definition=indicating the beginning unit in a series | synonyms=1st
3. definition=serving to set in motion | synonyms=inaugural, initiative, initiatory, maiden | examples=the magazine's inaugural issue; the initiative phase in the negotiations
4. definition=serving to begin | synonyms=beginning | examples=the beginning canto of the poem; the first verse
5. definition=ranking above all others | synonyms=foremost, world-class | examples=was first in her class; the foremost figure among marine artists
6. definition=highest in pitch or chief among parts or voices or instruments or orchestra sections | examples=first soprano; the first violin section

reasoning_content:
**Analyzing the "First" Claim**

Okay, so the text says this test was the *first* to reliably predict cancer development. My immediate thought is, alright, let's break down that "first." It's not just a casual descriptor; it's a claim about its place in history. My initial understanding is that it was the earliest – chronologically, it came before any other test with this capability. That's the most straightforward interpretation.

Let me just quickly run through the different senses of "first" to be sure. There's the temporal sense, like being *before* everything else, which seems spot-on here. Then there's the ordinal sense, like "1st" in a sequence – "the first step," or in a list of items; that would be if we were looking at a series of tests, not quite right. There are a few others: a starting point, initiating something, ranking or highest in some quality. None of those seem to fit the context as well as the initial temporal understanding. It's the chronological order that matters most here: this test was the initial breakthrough, the pioneering one. Therefore, the first sense is the best.


[User]
Which numbered sense of "individual" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan. This test was the first to predict reliably whether an <t>individual</t> could expect to develop cancer. Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded.

Senses:
1. definition=a human being | synonyms=person, someone, somebody, mortal, soul | examples=there was too much for one person to do
2. definition=a single organism

reasoning_content:
**Deconstructing the Term "Individual"**

Okay, so I'm looking at this text, and the word "individual" is used, and I need to clarify what that means, especially in the context of cancer prediction. The immediate thought is, it's referring to a human. Let's make sure we're on the right track. The word "individual" has a couple of definitions – one, the general sense of a human being, a person, a soul, which is what I'm guessing is relevant here. The second sense, referring to a single organism, is correct in that a human is an organism, but it's too broad for this specific context. In medicine and testing, we’re talking about a patient, a person.

To confirm my interpretation, I'll replace "individual" with the closest term. If I’m looking at "whether an individual could expect to develop cancer", I should be able to replace "individual" with "person". So I'll check that: "whether a person could expect to develop cancer". Bingo. It makes perfect sense that in this context the word is used to describe a human being.


[User]
Which numbered sense of "expect" (marked with <t></t>) is used in the context below? Return only the number of the correct sense.

Context: The Dedham, Mass., couple knew even before Bonnie became pregnant in 1987 that any child of theirs had a 50% chance of being at risk for retinoblastoma, an eye cancer that occurs about once every 20,000 births. Mr. Quinlan, 30 years old, knew he carried a damaged gene, having lost an eye to the rare tumor when he was only two months old -- after his mother had suffered the same fate when she was a baby. Because of the isolation of the retinoblastoma tumor-suppressor gene, it became possible last January to find out what threat the Quinlan baby faced. A test using new "genetic probes "showed that little Will Quinlan had not inherited a damaged retinoblastoma supressor gene and, therefore, faced no more risk than other children of developing the rare cancer. "It made our New Year, "says Mr. Quinlan. This test was the first to predict reliably whether an individual could <t>expect</t> to develop cancer. Equally important, the initial discovery of the gene that controls retinal cell growth, made by a Boston doctor named Thaddeus Dryja, has opened a field of cancer study, which in recent months has exploded.

Senses:
1. definition=regard something as probable or likely | synonyms=anticipate | examples=The meteorologists are expecting rain for tomorrow
2. definition=consider obligatory; request and expect | synonyms=ask, require | examples=We require our secretary to be on time; Aren't we asking too much of these children?
3. definition=look forward to the probable occurrence of | synonyms=look, await, wait | examples=We were expecting a visit from our relatives; She is looking to a promotion
4. definition=consider reasonable or due | examples=I'm expecting a full explanation as to why these files were destroyed
5. definition=look forward to the birth of a child | examples=She is expecting in March
6. definition=be pregnant with | synonyms=have a bun in the oven, bear, carry, gestate | examples=She is bearing his child; The are expecting another child in January

reasoning_content:
**Analyzing the Nuances of "Expect"**

Okay, so the task is to decipher the meaning of "expect" in that particular sentence: "This test was the first to predict reliably whether an individual could expect to develop cancer." My immediate thought is to consider the various shades of meaning that word holds, given how context-dependent it is.

First, I quickly break it down. I know "expect" can mean to *anticipate*, which, in this case, would align with regarding something as probable or likely. Hmm, "expect to develop cancer"... yeah, that fits remarkably well. It's about looking ahead and believing something will happen.

Then I quickly check the other possibilities, just to be sure. Does it mean to consider something obligatory? No, that doesn't gel with this context. Could it mean looking forward to something, like a visit or promotion? Definitely not. Does it imply considering something reasonable or due, like expecting an explanation? Again, not a good fit. And the pregnancy-related senses are entirely off-base here.

Therefore, after running through the available definitions, I'm confident that the intended meaning is the first one - to regard something as probable or likely. "Expect to develop cancer" perfectly encapsulates the idea of anticipating a future outcome, based on the test's predictive power. The other senses are easily ruled out as being inappropriate to the sentence in question.