[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
2. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
3. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
4. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
5. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
6. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
7. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
8. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
9. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
10. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
11. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
12. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
13. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
14. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
15. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
16. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
17. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
18. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
19. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
20. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
21. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
22. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
23. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
24. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
25. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
26. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
27. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
28. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
29. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
30. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
31. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
32. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
33. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
34. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
35. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
36. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
37. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
38. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
39. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
40. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
41. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
42. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
43. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
44. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the "Give" Lemma in Context**

Okay, so the task at hand is to analyze the word "given," specifically as it relates to the lemma "give." The surface form is "given," which, in this context, appears in the phrase, "Alimta should only be given under the supervision...". This is interesting. "Alimta" is clearly a medication, an anticancer chemotherapy. Therefore, "given" in this instance likely refers to the act of administering or providing the medicine to a patient.

Let's look at the senses available. The second sense, specifically sense_key=give%2:40:13::, with the definition "give (as medicine)" and the example sentence "I gave him the drug" jumps out immediately. This fits the context perfectly. We have a medicine ("Alimta") being "given" to someone. The example sentence also perfectly matches the structure of the target sentence.

Excellent. That looks like the clear winner. Now, let's just confirm that it meets the necessary JSON formatting constraint. {"sense_index": 2} should do the trick. Done.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: doctor
Target surface form: doctor
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
2. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
3. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{
  "sense_index": 2
}
```

finish_reason: stop

content:
```json
{
  "sense_index": 2
}
```

role: assistant

reasoning_content:
**Analyzing the Context of "Doctor"**

Okay, so the target word is "doctor," and the surrounding text is all about Alimta, anticancer chemotherapy, and medical supervision. My initial thought process is to quickly consider the potential senses. I run through a quick mental inventory: could it be a children's game, a historical religious figure, or even someone with a Ph.D.? But that's quickly dismissed. The phrase "anticancer chemotherapy" and the mention of "supervision" are the keys here. This clearly points to a medical context.

Therefore, the only logical and, frankly, the only accurate sense is that of a licensed medical practitioner – a physician. Sense 2 nails it. No need to delve any further; the context provides a very clear and unambiguous definition. It's a straightforward case of word sense disambiguation, and I can move on.

type: thinking

service_tier: default

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: use
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
2. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat
5. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
6. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
7. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

content:
```json
{"sense_index": 6}
```

reasoning_content:
**Analyzing the "Use" Context**

Okay, so the target is "use," and the surface form is just "use" – straightforward enough. The context I'm given is "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy." Right away, I start to parse the possibilities, considering the typical senses of "use." I've got a list of potential interpretations: habit, economic utilization, a service, a legal right, function or purpose, the act of using, and even manipulation.

Given my understanding of medical contexts, the phrase "qualified in the use of" immediately leans towards some kind of practical application. The key here is "anticancer chemotherapy." Thinking this through, I'm leaning toward the act of employing, utilizing, or exercising the chemo. I need to make the right selection, here.

Scanning the definitions, sense 6, "the act of using," seems like the best fit. The synonyms like "usage," "utilization," "employment," and "exercise" are spot-on. Then I see the example, "skilled in the utilization of computers," and it's a perfect match for "qualified in the use of anticancer chemotherapy." That's the match I'm looking for. This is about skill, not a habit, not a purpose, not a service. It's about performing a specific action: administering the chemotherapy. Sense 6 is the clear winner here. I'm selecting sense 6.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended <t>dose</t> of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
2. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
3. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons
4. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Meaning of "Dose" in a Medical Context**

Okay, so I need to define "dose" within the context of Alimta. The text tells me it's a medicine, specifically an "anticancer medicine." My initial thought is to consider a few definitions. Candidate 2, "a measured portion of medicine taken at any one time" (synonyms: dosage), seems promising. Candidate 4, "the quantity of an active agent (substance or radiation) taken in or absorbed at any one time," also warrants consideration.

Given that Alimta is a drug, I'm leaning toward the idea of a measured portion. Wait... "anticancer medicine" cements that line of thinking. It can't be anything else, really.

I'm checking the definitions of the word “dose”. Sense 2's definition, "a measured portion of medicine taken at any one time," looks like a good match. Meanwhile, I am evaluating that "the quantity of an active agent."

The sentence confirms this: "The recommended dose of Alimta is 500 mg..." Right, it's referring to a specific portion of medicine. Sense 2 fits perfectly: a measured portion of medicine taken at any one time. That's the most appropriate fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: mg
Target surface form: mg
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=mg%1:27:00:: | definition=a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) | synonyms=magnesium, atomic number 12
2. sense_key=mg%1:23:00:: | definition=one thousandth (1/1,000) gram | synonyms=milligram

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Meaning of "mg" in Context**

Okay, so the target is "mg," and that's also the surface form – simple enough. Now, I need to figure out what it *means* here. The context is this phrase about the "recommended dose of Alimta is 500 mg per square metre of body surface area..." Right away, my mind jumps to the two likely senses: is it magnesium, or is it milligram?

Given this pharmaceutical setting, this is a dosing instruction, isn't it? Well, given my knowledge in the field, "mg" almost always means "milligram" in this sort of context, as it's a standard unit of measurement for drug dosages. So, sense number two, milligram, is the obvious and correct interpretation. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
2. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
3. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
4. sense_key=body%1:07:01:: | definition=the main mass of a thing
5. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
6. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
7. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
8. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
9. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted
10. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
11. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

content:
```json
{"sense_index": 3}
```

reasoning_content:
**Analyzing the Meaning of "Body" in Context**

Okay, so the target word here is "body," and the phrase is "body surface area" within the context of Alimta dosage. Let's break this down. My mind immediately goes through the potential senses, considering them as I would if I were analyzing the word in a semantic task.

First, I consider the possibility of a "resonating chamber," but that doesn't fit at all. Then I think about the torso, or "body excluding head/neck/limbs," but that seems too narrow. The "main mass" or a "collection of particulars" are also possibilities, but quickly dismissed as not quite right. "Individual 3-dimensional object" is another tempting, but ultimately wrong option. I also dismiss "group of persons," "property of holding together," "external structure of a vehicle," "central message of a communication," and "dead animal or person" as completely irrelevant in this medical context.

Thinking further, the best interpretation has to be "the entire structure of an organism." It just clicks – that's what's needed for calculating a surface area relevant to drug dosage. The patient's entire physical being, their complete form, is what the calculation is based on. Therefore, sense number 3 – the entire structure of an organism, as a human being - is the clearest and most accurate. That is the indexed sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: calculate
Target surface form: calculated
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (<t>calculated</t> using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=calculate%2:32:01:: | definition=predict in advance | synonyms=forecast
2. sense_key=calculate%2:31:05:: | definition=have faith or confidence in | synonyms=count, bet, depend, look, reckon | examples=you can count on me to help you any time; Look to your friends for support
3. sense_key=calculate%2:31:00:: | definition=make a mathematical calculation or computation | synonyms=cipher, cypher, compute, work out, reckon, figure
4. sense_key=calculate%2:31:03:: | definition=judge to be probable | synonyms=estimate, reckon, count on, figure, forecast
5. sense_key=calculate%2:40:00:: | definition=keep an account of | synonyms=account
6. sense_key=calculate%2:31:02:: | definition=specifically design a product, event, or activity for a certain public | synonyms=aim, direct

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Verb "Calculate" in Context**

Okay, so the word I'm focusing on is "calculate," specifically as it appears in the surface form "calculated." My context is a sentence about determining a drug dose based on body surface area, which itself is *calculated* using height and weight. This is a pretty straightforward math problem – we're determining a numerical value based on some input variables.

Let's look at the candidate senses. I've got "predict in advance," "have faith or confidence in," "make a mathematical calculation," "judge to be probable," "keep an account of," and "specifically design." Hmm, immediately, the third sense, "make a mathematical calculation or computation," jumps out. This *must* be the intended meaning.

"Calculated using the patient's height and weight." This is directly referencing the act of computing the body surface area with a mathematical formula and patient specific values. It's a clear fit! Let me quickly double-check that sense's definition and synonyms: `calculate%2:31:00::` means "make a mathematical calculation or computation" with synonyms like "cipher," "compute," and "figure." Yep, absolutely spot on. The context perfectly supports the numerical computation sense of the verb.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: using
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated <t>using</t> the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
2. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
3. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
4. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
5. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Deconstructing "Using" in Context**

Alright, the target word is "using" and the surrounding text is "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient's height and weight)." My initial reaction is to consider the possible senses – always the first step. I quickly run through the likely candidates: "use up," "avail oneself to," "seek or achieve an end by using," "take or consume," "put into service," and the habitual sense of "used to."

Given the context of a calculation involving patient height and weight, the less metaphorical options are going to be more likely. "Use up" and "take or consume" are clearly out. "Avail oneself to" is a possibility but feels a bit strained. Similarly, "seek or achieve an end by using" feels less direct. The habitual "used to" is obviously wrong here.

That leaves "put into service; make work or employ for a particular purpose." This seems highly probable. The phrase "calculated *using* the patient's height and weight" strongly suggests *employing* those measurements as part of a calculation process. So, it's essentially "utilizing" or "applying" them.

Let me just confirm. Okay, let's substitute "employing" for "using". "The recommended dose...calculated *employing* the patient's height and weight." Yes, that works perfectly. It means we are making use of the values in the calculation, which is the correct sense. It's definitely sense number 5.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patient
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the <t>patient</t> s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role
2. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing "Patient" in Medical Context**

Okay, so I'm presented with "patient" as the lemma and surface form, and the context is a medical dosage recommendation for Alimta. The provided context screams *medical* application, specifically dealing with dosage calculation based on height and weight. Immediately, my mind jumps to the two potential senses: the general "affected entity" sense versus the *medical* sense of a person needing care.

Given the context of a drug dosage, calculating based on body surface area, it's a no-brainer. The "affected entity" sense is too broad here. We're explicitly talking about a person *receiving* medical intervention. The second sense, "a person who requires medical care," is the clear and only logical interpretation. No need for further deep analysis; the context perfectly aligns with sense 2. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: height
Target surface form: height
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s <t>height</t> and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=height%1:26:00:: | definition=the highest level or degree attainable; the highest stage of development | synonyms=acme, elevation, peak, pinnacle, summit, superlative | examples=his landscapes were deemed the acme of beauty; the artist's gifts are at their acme
2. sense_key=height%1:07:01:: | definition=(of a standing person) the distance from head to foot | synonyms=stature
3. sense_key=height%1:07:02:: | definition=elevation especially above sea level or above the earth's surface | synonyms=altitude | examples=the altitude gave her a headache
4. sense_key=height%1:07:00:: | definition=the vertical dimension of extension; distance from the base of something to the top | synonyms=tallness

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Meaning of "Height"**

Okay, the target word is "height," and the surrounding text mentions a medication dose calculated based on body surface area, using the patient's height and weight. My expertise immediately tells me this is likely a straightforward application of the word, but I need to be precise. Let's see... the candidate senses are: "highest level/degree," "distance from head to foot," "elevation above sea level," and "vertical dimension of extension."

Immediately, sense 2 jumps out: "(of a standing person) the distance from head to foot (stature)." That's precisely what's needed for calculating body surface area – it's referring to the patient's physical stature. To be extra certain, I need to confirm the context.

"Calculated using the patient's height and weight..." Yes, the context explicitly implies a physical attribute of a person. Sense 2 fits perfectly. This is the patient's stature. No ambiguity here. I'm returning sense index 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: weight
Target surface form: weight
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and <t>weight</t>). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=weight%1:07:00:: | definition=the vertical force exerted by a mass as a result of gravity
2. sense_key=weight%1:23:02:: | definition=(statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance | synonyms=weighting
3. sense_key=weight%1:23:01:: | definition=a system of units used to express the weight of something | synonyms=system of weights
4. sense_key=weight%1:06:00:: | definition=an artifact that is heavy
5. sense_key=weight%1:07:01:: | definition=the relative importance granted to something | synonyms=weightiness | examples=his opinion carries great weight; the progression implied an increasing weightiness of the items listed
6. sense_key=weight%1:23:00:: | definition=a unit used to measure weight | synonyms=weight unit | examples=he placed two weights in the scale pan
7. sense_key=weight%1:06:01:: | definition=sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms | synonyms=free weight, exercising weight
8. sense_key=weight%1:12:00:: | definition=an oppressive feeling of heavy force | examples=bowed down by the weight of responsibility

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Meaning of "Weight" in Context**

Okay, so the target is "weight", the surface form is "weight", and the context is about calculating a drug dosage based on a patient's height and weight. My immediate thought is, "Okay, this is about the patient's *physical* weight, not some abstract concept." The text explicitly mentions "body surface area" and how it's calculated using both. That strongly suggests we're dealing with the physical property of mass affected by gravity.

Candidate 1, *weight%1:07:00:: the vertical force exerted by a mass as a result of gravity*, feels like the obvious fit, but I always need to be thorough. I'll quickly check the other candidates to be certain. "Heavy artifact" (candidate 4) and sports equipment (candidate 7) and oppressive feeling (candidate 8) are all clearly irrelevant here. Statistics, systems of units, and units of measurement are possibilities (candidates 2, 3, and 6) but seem like a reach in this context where "height and weight" are paired to measure a patient. Importance (candidate 5) doesn't even make sense here, so it's a non-starter.

Let me just quickly confirm that the sense in candidate 1 is the standard physical property. Yes, that is standard, I'm confident. I'm going to choose the physical property definition, weight%1:07:00::. It is, undoubtedly, the vertical force exerted by a mass as a result of gravity. This is about the patient's body weight.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is <t>given</t> once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
2. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
3. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
4. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
5. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
6. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
7. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
8. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
9. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
10. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
11. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
12. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
13. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
14. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
15. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
16. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
17. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
18. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
19. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
20. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
21. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
22. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
23. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
24. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
25. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
26. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister
27. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
28. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
29. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
32. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
33. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
34. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
35. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
36. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
37. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
38. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
39. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
40. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
41. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
42. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
43. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
44. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 31}
```

content:
```json
{"sense_index": 31}
```

reasoning_content:
**Analyzing the Usage of "Given"**

Okay, so the target word is "give", specifically the past participle "given", and the sentence is "It is given once every three weeks as an intravenous infusion lasting 10 minutes." My immediate thought is, this is likely a medical or pharmaceutical context. "Given" here isn't about, say, gifting something.

I need to nail down the precise meaning. Let's see... looking at the senses, I'm expecting something related to administration, perhaps even dosage.

Ah, there it is: sense 31, with the sense key `give%2:40:13::` – "give (as medicine)"! The definition is "give (as medicine)," and the example "I gave him the drug" perfectly aligns with how "given" is used here. Alimta, the drug, is being "given" as an infusion. That's a textbook match. I can confidently classify the usage based on this sense.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: once
Target surface form: once
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given <t>once</t> every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=once%4:02:01:: | definition=at a previous time | synonyms=formerly, at one time, erstwhile, erst | examples=at one time he loved her; her erstwhile writing
2. sense_key=once%4:02:00:: | definition=on one occasion | synonyms=one time, in one case | examples=once I ran into her
3. sense_key=once%4:02:02:: | definition=as soon as | examples=once we are home, we can rest

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Usage of "Once"**

Okay, here's the breakdown. The word I need to understand is "once" in that sentence: "It is given once every three weeks as an intravenous infusion lasting 10 minutes." My mind immediately jumps to a few possible meanings: "at a previous time," "on one occasion," or even "as soon as."

Since the phrase is "once *every three weeks*," the intended meaning is clearly about frequency. It's referring to something happening periodically. Thinking this through, "once every three weeks" means "one time every three weeks." That directly maps onto the sense of "on one occasion" – sense 2. It’s definitely not "formerly" (sense 1), nor "as soon as" (sense 3). Those would change the meaning completely.

Therefore, sense 2 is the correct one. The word "once" here indicates a single instance within a defined time period. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: every
Target surface form: every
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once <t>every</t> three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=every%5:00:02:all:00 | definition=each and all of a series of entities or intervals as specified | examples=every third seat; every two hours
2. sense_key=every%5:00:00:all:00 | definition=(used of count nouns) each and all of the members of a group considered singly and without exception | examples=every person is mortal; every party is welcome

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Usage of "Every"**

Okay, so I'm dissecting the word "every" in the context of "once every three weeks." My initial thought is to pinpoint the exact semantic role this "every" is playing here. I have two candidate definitions in mind.

Candidate 1 frames "every" as referring to "each and all of a series of entities or intervals as specified." Excellent, that immediately jumps out as a strong possibility, it fits examples like "every third seat" or "every two hours" which are exactly the kind of phrases that I'm looking to contextualize.

Candidate 2 defines "every" as it relates to a whole "group considered singly and without exception". This option seems too broad. Phrases like "every person is mortal" or "every party is welcome" are not the correct framing, as those cases are about group membership, not cycles or repetition.

Therefore, "every three weeks" is clearly an interval, a cyclical occurrence. That makes candidate 1 the superior match. Case closed.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: week
Target surface form: weeks
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three <t>weeks</t> as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=week%1:28:02:: | definition=a period of seven consecutive days starting on Sunday | synonyms=calendar week
2. sense_key=week%1:28:00:: | definition=any period of seven consecutive days | synonyms=hebdomad | examples=it rained for a week
3. sense_key=week%1:28:01:: | definition=hours or days of work in a calendar week | synonyms=workweek | examples=they worked a 40-hour week

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Meaning of "Weeks"**

Okay, so the target is "week," and it appears as "weeks" in the sentence "It is given once every three weeks as an intravenous infusion lasting 10 minutes." My expert intuition immediately kicks in, and I start breaking down the possibilities.

I see three potential interpretations: a calendar week starting on Sunday (Candidate 1), any period of seven consecutive days (Candidate 2), or a workweek (Candidate 3). The context, however, is a medical one – specifically, discussing the timing of an infusion.

Given this medical setting and the phrase "every three weeks," I'm almost certain we're talking about a *regular interval* of time. I know from experience that in medical contexts like this, intervals are typically described in terms of straightforward 7-day periods, not specific calendar weeks that begin on a Sunday, or working hours. The focus is on the *duration* of the interval. Therefore, the best, and most clinically relevant, interpretation is Candidate 2: "any period of seven consecutive days."


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous <t>infusion</t> lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent
2. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)
3. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
4. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

content:
```json
{"sense_index": 4}
```

reasoning_content:
**My Analysis of "Infusion" in a Medical Context**

Okay, so the word is "infusion," and the context is an "intravenous infusion lasting 10 minutes." Right away, my mind jumps to a medical procedure. The phrase "intravenous" is key – it points directly to introducing something into a vein.

Let's break down the potential meanings, just to be thorough. The first sense that comes to mind is metaphorical: the act of *infusing* a quality or element, a general concept of modification. However, that feels less precise in this setting. Sense two brings up extracting properties, which while somewhat relevant is not the primary definition at play. Sense three is a solution obtained by steeping, as in tea. Again, not fitting the description well.

Then, there's sense four, which is *it*: the passive introduction of a substance—a fluid, drug, or electrolyte—into a vein or between tissues. "Intravenous infusion" *is* specifically a medical term describing the introduction of a substance directly into a vein. That nails it. The timeframe of 10 minutes suggests a controlled and relatively rapid delivery of a substance. No need to look further. Sense four is the relevant one, and it's quite clear-cut in this situation.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: last
Target surface form: lasting
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion <t>lasting</t> 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=last%2:42:01:: | definition=continue to live through hardship or adversity | synonyms=survive, live, live on, go, endure, hold up | examples=We went without water and food for 3 days; These superstitions survive in the backwaters of America
2. sense_key=last%2:42:00:: | definition=persist for a specified period of time | synonyms=endure | examples=The bad weather lasted for three days

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Target Word "Lasting"**

Okay, so the task is to pinpoint the specific meaning of "lasting" in this context. The target word, the lemma is "last," and the context is "...It is given once every three weeks as an intravenous infusion lasting 10 minutes." Alright, let's break this down systematically.

First, I consider the possible senses. Sense 1, "continue to live through hardship or adversity," doesn't fit at all. We're talking about an infusion, not survival. That's immediately discarded.

Now, Sense 2: "persist for a specified period of time," for example, "The bad weather lasted for three days." Bingo! An infusion "lasting 10 minutes" clearly refers to its duration. It's a precise temporal measurement.

Therefore, the only reasonable interpretation here, as I see it, is Sense 2: the infusion's persistence within a specific timeframe - its 10-minute duration. The correct sense is confirmed as a match.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: minute
Target surface form: minutes
Context:
Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 <t>minutes</t>. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta.

Candidate senses:
1. sense_key=minute%1:28:00:: | definition=a unit of time equal to 60 seconds or 1/60th of an hour | synonyms=min | examples=he ran a 4 minute mile
2. sense_key=minute%1:10:00:: | definition=a short note | examples=the secretary keeps the minutes of the meeting
3. sense_key=minute%1:07:00:: | definition=distance measured by the time taken to cover it | synonyms=hour | examples=we live an hour from the airport; its just 10 minutes away
4. sense_key=minute%1:28:01:: | definition=an indefinitely short time | synonyms=moment, mo, second, bit | examples=wait just a moment; in a mo
5. sense_key=minute%1:23:00:: | definition=a unit of angular distance equal to a 60th of a degree | synonyms=arcminute, minute of arc
6. sense_key=minute%1:28:02:: | definition=a particular point in time | synonyms=moment, second, instant | examples=the moment he arrived the party began

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Usage of "Minutes"**

Okay, the target word is "minutes," with the base form being "minute." The context sentence is: "It is given once every three weeks as an intravenous infusion lasting 10 minutes." My initial thought is that this is straightforward, but let's be methodical.

I'm presented with several senses: a unit of time (sense 1), distance (sense 3), a short time (sense 4), and a specific point in time (sense 6). Given that the sentence describes an "intravenous infusion lasting 10 minutes," it's almost certainly referring to duration – a period of time. Sense 3, distance, doesn't fit at all. Sense 4, an indefinitely short time, seems incorrect. Sense 6, a particular point in time, also doesn't fit the context of something *lasting*. The definition for sense 1, "a unit of time equal to 60 seconds or 1/60th of an hour," seems like the most probable option.

To confirm this, I’m going to consider it. With the specific phrasing "lasting 10 minutes," the meaning is unambiguously the unit of time, and the definition provided seems to match perfectly. The definition lines up exactly with the duration of the infusion. Yes, sense 1 is definitely the correct sense here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: reduce
Target surface form: reduce
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To <t>reduce</t> side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=reduce%2:30:00:: | definition=cut down on; make a reduction in | synonyms=cut down, cut back, trim, trim down, trim back, cut | examples=reduce your daily fat intake; The employer wants to cut back health benefits
2. sense_key=reduce%2:30:02:: | definition=cook until very little liquid is left | synonyms=boil down, concentrate | examples=The cook reduced the sauce by boiling it for a long time
3. sense_key=reduce%2:30:05:: | definition=reduce in size; reduce physically | synonyms=shrink | examples=Hot water will shrink the sweater; Can you shrink this image?
4. sense_key=reduce%2:30:04:: | definition=make smaller | synonyms=scale down | examples=reduce an image
5. sense_key=reduce%2:30:01:: | definition=narrow or limit | synonyms=tighten | examples=reduce the influx of foreigners
6. sense_key=reduce%2:29:00:: | definition=take off weight | synonyms=melt off, lose weight, slim, slenderize, thin, slim down
7. sense_key=reduce%2:30:10:: | definition=be cooked until very little liquid is left | synonyms=boil down, decoct, concentrate | examples=The sauce should reduce to one cup
8. sense_key=reduce%2:30:12:: | definition=destress and thus weaken a sound when pronouncing it
9. sense_key=reduce%2:30:08:: | definition=reduce in scope while retaining essential elements | synonyms=abridge, foreshorten, abbreviate, shorten, cut, contract | examples=The manuscript must be shortened
10. sense_key=reduce%2:40:00:: | definition=lessen and make more modest | examples=reduce one's standard of living
11. sense_key=reduce%2:30:11:: | definition=be the essential element | synonyms=come down, boil down | examples=The proposal boils down to a compromise
12. sense_key=reduce%2:35:01:: | definition=reposition (a broken bone after surgery) back to its normal site
13. sense_key=reduce%2:40:04:: | definition=simplify the form of a mathematical equation of expression by substituting one term for another
14. sense_key=reduce%2:37:00:: | definition=lower in grade or rank or force somebody into an undignified situation | examples=She reduced her niece to a servant
15. sense_key=reduce%2:35:00:: | definition=undergo meiosis | examples=The cells reduce
16. sense_key=reduce%2:30:03:: | definition=to remove oxygen from a compound, or cause to react with hydrogen or form a hydride, or to undergo an increase in the number of electrons | synonyms=deoxidize, deoxidise
17. sense_key=reduce%2:30:09:: | definition=lessen the strength or flavor of a solution or mixture | synonyms=dilute, thin, thin out, cut | examples=cut bourbon
18. sense_key=reduce%2:41:00:: | definition=bring to humbler or weaker state or condition | examples=He reduced the population to slavery
19. sense_key=reduce%2:41:03:: | definition=put down by force or intimidation | synonyms=repress, quash, keep down, subdue, subjugate | examples=The government quashes any attempt of an uprising; China keeps down her dissidents very efficiently
20. sense_key=reduce%2:30:06:: | definition=make less complex | examples=reduce a problem to a single question

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 1}
```

reasoning_content:
**Analyzing the Meaning of "Reduce" in a Clinical Context**

Okay, so the sentence reads, "...patients should take a corticosteroid to *reduce* side effects..." My task is to determine the precise meaning of "reduce" here. The target is "reduce" acting upon "side effects," so it's about diminishing the severity or occurrence of those effects. Immediately, the sense of lessening or decreasing comes to mind. Let's delve into the senses.

Looking at the definitions, sense 1, "cut down on; make a reduction in," seems the most appropriate. Synonyms like "cut back," "trim down," etc., all point to a decrease, which aligns with my understanding of mitigating side effects.

Let me explore other possibilities. Perhaps sense 10, "lessen and make more modest," could fit. However, "reduce one's standard of living" doesn't seem to apply to side effects. No, it's not a change in lifestyle.

Thinking more carefully, could it be a question of making something smaller, sense 4 "make smaller (scale down)"? No, this is not about diminishing the *size* of the effects. It is about a decrease in their *magnitude*.

So, sense 1, "cut down on; make a reduction in," appears to be the most relevant and precise. Let's verify: "To reduce side effects" directly translates to "to make a reduction in side effects." Yes, that holds up perfectly. Sense 1 is the clear winner.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: side_effect
Target surface form: side effects
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce <t>side effects</t>, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=side_effect%1:26:00:: | definition=a secondary and usually adverse effect of a drug or therapy | examples=severe headaches are one of the side effects of the drug
2. sense_key=side_effect%1:19:00:: | definition=any adverse and unwanted secondary effect | synonyms=fallout | examples=a strategy to contain the fallout from the accounting scandal

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{
  "sense_index": 1
}
```

content:
```json
{
  "sense_index": 1
}
```

reasoning_content:
**Analyzing the Nuances of "Side Effects"**

Okay, so the target term is "side effects." My immediate focus is on the context: it mentions Alimta, which, as a chemotherapy expert, I instantly recognize as an anticancer drug. That narrows the field significantly. The text specifies "to reduce side effects" and links this to specific interventions like corticosteroids, folic acid, and vitamin B12 injections *during* Alimta treatment.

Let's break down the potential senses. I'm presented with two definitions: first, "a secondary and usually adverse effect of a drug or therapy," and second, "any adverse and unwanted secondary effect." While both are valid, the context strongly leans towards the first. The link to an anticancer chemotherapy agent is the key. The phrase "To reduce side effects" implies a treatment response to mitigate a drug's negative effects. The interventions listed—corticosteroids, folic acid, and B12—are commonly used to manage the adverse consequences of chemotherapy specifically. I can immediately discard the general definition of any unwanted secondary effect, as it does not capture the specific nature of a drug’s reaction on the body.

Therefore, sense one, "a secondary and usually adverse effect of a drug or therapy," is the most precise and applicable in this instance. It perfectly captures the clinical relevance we're dealing with here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, <t>patients</t> should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role
2. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Context of "Patients"**

Okay, so the target word is "patients," and my goal is to figure out which sense of the word is being used here. The surrounding text mentions "Alimta," a medicine administered under a doctor's supervision, and details about dosage and side effect management. The key phrases are "recommended dose," "reduce side effects," and "during treatment with Alimta."

Given this medical context, it's pretty clear that sense 2, "a person who requires medical care," is the intended meaning. While "patient" can have other meanings, like in linguistics as a semantic role, that's completely irrelevant here. The discussion of dosages, corticosteroids, and side effects screams "medical context." No need to overthink this; it's a straightforward application of domain knowledge. We're talking about individuals receiving medical treatment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a <t>type</t> of vitamin), and receive injections of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
2. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
3. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up
6. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the Meaning of "Type"**

Okay, so the target is "type" and, naturally, the surface form is "type" too. The context is pretty straightforward: "...patients should take a corticosteroid and folic acid (a type of vitamin)..." My initial assessment is that "type" here indicates a subdivision or a specific *kind* of something. Folic acid is being described as belonging to the broader category of vitamins.

Let's quickly run through the senses and eliminate the non-fitting definitions:

*   **Sense 1** (*type%1:10:00:: all of the tokens of the same symbol*) is clearly wrong. Not relevant.
*   **Sense 2** (*type%1:14:01:: (biology) the taxonomic group...*) This is biological taxonomy, also incorrect.
*   **Sense 3** (*type%1:18:00:: a person of a specified kind*) is clearly wrong. Not relevant.
*   **Sense 4** (*type%1:10:01:: printed characters*) refers to printed characters. Not relevant.
*   **Sense 5** (*type%1:06:00:: a small metal block*) refers to metal blocks. Not relevant.

That leaves **Sense 6** (*type%1:09:00:: a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?*). This one nails it. The example sentence provided solidifies the fit. It perfectly captures the relationship between folic acid and vitamins – folic acid is a specific kind *of* vitamin. Sense 6 is the clear winner here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: injection
Target surface form: injections
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive <t>injections</t> of vitamin B12 during treatment with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=injection%1:27:00:: | definition=any solution that is injected (as into the skin) | synonyms=injectant
2. sense_key=injection%1:04:00:: | definition=the forceful insertion of a substance under pressure
3. sense_key=injection%1:04:01:: | definition=the act of putting a liquid into the body by means of a syringe | synonyms=shot | examples=the nurse gave him a flu shot

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
**Analyzing the "Injection" Context**

Okay, so the target is "injection," and the surface form is "injections" – pretty straightforward so far. The context is "receive injections of vitamin B12 during treatment..." My immediate thought is, does "receive injections" refer to the solution itself or the *act* of administering it? Thinking about it, "receive injections" strongly suggests the act – like receiving shots.

Alright, let's examine the candidate senses:

1.  *Injection%1:27:00:* This is about the *injectant* itself, the solution.
2.  *Injection%1:04:00:* This is the *forceful insertion* of the substance, a more general process.
3.  *Injection%1:04:01:* This specifically describes the *act* of putting liquid into the body with a syringe – the "shot."

The phrase "receive injections of vitamin B12" has strong parallels to "giving him a flu shot." They are receiving the *administration* of the medicine. Could it be the substance? Not likely. We usually say "receive shots". "Shots" are a synonym for sense 3. Therefore, sense 3 is the best fit.

Let me think this through one more time. The context is: "...receive injections of vitamin B12...". "Injections" here is the *act* of administering vitamin B12 via syringe. The synonym "shot" fits perfectly here: "receive shots of vitamin B12." That works. And then, "receive injectants of vitamin B12"? No, this seems very bad. That leaves us with sense 3, which is the perfect solution.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treatment
Target surface form: treatment
Context:
The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes. To reduce side effects, patients should take a corticosteroid and folic acid (a type of vitamin), and receive injections of vitamin B12 during <t>treatment</t> with Alimta. When Alimta is given with cisplatin, an anti-emetic medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.

Candidate senses:
1. sense_key=treatment%1:04:01:: | definition=the management of someone or something | synonyms=handling | examples=the handling of prisoners; the treatment of water sewage
2. sense_key=treatment%1:04:00:: | definition=care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) | synonyms=intervention
3. sense_key=treatment%1:10:00:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=discussion, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased
4. sense_key=treatment%1:07:00:: | definition=a manner of dealing with something artistically | examples=his treatment of space borrows from Italian architecture

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

content:
```json
{"sense_index": 2}
```

reasoning_content:
**Analyzing the Meaning of "Treatment" in a Medical Context**

Okay, so the word I'm focusing on is "treatment," and it's used in relation to taking Alimta medication. My immediate task is to nail down the precise meaning. Let's see... I've got a few potential senses in my mental dictionary.

First, "treatment" as management or handling. Doesn't quite feel right in this context, does it? We're not just *managing* a thing, we're doing something specific *to* a patient.

Next, we have "care provided to improve a situation," particularly medical procedures. Ah, now we're getting warmer! This one specifically mentions "medical procedures or applications that are intended to relieve illness or injury," which directly aligns with the idea of administering Alimta, a chemotherapeutic agent. That sounds promising.

Then there’s "an extended communication dealing with a topic" – essentially, a discussion. Obviously wrong. Not a good fit at all.

Finally, "a manner of dealing with something artistically." Also not appropriate here.

Therefore, the second sense – "care provided to improve a situation," especially medical procedures – is undoubtedly the correct one. The context of Alimta as a medication makes it clear that we're talking about medical intervention to alleviate illness. This is definitely the interpretation I'll be using.