[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: spread
Target surface form: spread
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=spread%2:35:00:: | definition=distribute or disperse widely | synonyms=distribute | examples=The invaders spread their language all over the country
2. sense_key=spread%2:35:07:: | definition=become distributed or widespread | synonyms=propagate | examples=the infection spread; Optimism spread among the population
3. sense_key=spread%2:42:00:: | definition=spread across or over | synonyms=overspread | examples=A big oil spot spread across the water
4. sense_key=spread%2:35:03:: | definition=spread out or open from a closed or folded state | synonyms=unfold, spread out, open | examples=open the map; spread your arms
5. sense_key=spread%2:32:00:: | definition=cause to become widely known | synonyms=circulate, circularize, circularise, distribute, disseminate, propagate | examples=spread information; circulate a rumor
6. sense_key=spread%2:32:02:: | definition=become widely known and passed on | synonyms=go around, circulate | examples=the rumor spread; the story went around in the office
7. sense_key=spread%2:38:00:: | definition=strew or distribute over an area | synonyms=scatter, spread out | examples=He spread fertilizer over the lawn; scatter cards across the table
8. sense_key=spread%2:38:02:: | definition=move outward | synonyms=diffuse, spread out, fan out | examples=The soldiers fanned out
9. sense_key=spread%2:35:12:: | definition=cover by spreading something over | examples=spread the bread with cheese
10. sense_key=spread%2:35:13:: | definition=distribute over a surface in a layer | examples=spread cheese on a piece of bread

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given the context: "Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to <t>spread</t> easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before". The target word is "spread" in the phrase "likely to spread easily, to other parts of the body". This refers to the spread of cancer, meaning the cancer metastasizes. The sense needed is the intransitive sense of "spread": to become distributed or widespread, especially of a disease or condition. Looking at the candidates:

1. distribute or disperse widely (transitive)
2. become distributed or widespread (intransitive) – example: "the infection spread", which fits cancer spreading.
3. spread across or over (like a liquid)
4. unfold
5. cause to become widely known (transitive)
6. become widely known (of rumors)
7. strew or distribute over an area (transitive)
8. move outward (intransitive, like soldiers fanning out)
9. cover by spreading something over
10. distribute over a surface in a layer

Sense 2 seems best: definition "become distributed or widespread", synonyms "propagate", example "the infection spread". Cancer is like an infection, it spreads. Sense 3 is more about physical spreading over a surface, but not necessarily metastasis. Sense 8 is about moving outward, but the example is soldiers fanning out, which might be less fitting than sense 2's focus on widespread distribution. Sense 2 specifically mentions "the infection spread", which parallels the cancer context. So I'll go with sense_index


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: easily
Target surface form: easily
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread <t>easily</t>, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=easily%4:02:01:: | definition=with ease (`easy' is sometimes used informally for `easily') | synonyms=easy | examples=she was easily excited; was easily confused
2. sense_key=easily%4:02:06:: | definition=without question | examples=easily the best book she's written
3. sense_key=easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
We are asked: "Target lemma: easily" and "Target surface form: easily" in the context about Alimta. The target word is "easily" in the phrase "has spread, or is likely to spread easily, to other parts of the body". We need to choose the best sense among three candidates.

Let's analyze the context: "when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body)". Here, "easily" modifies "spread" and means "with little difficulty" or "readily". The cancer spreads easily to other parts of the body.

Candidate senses:
1. easily%4:02:01:: | definition=with ease | synonyms=easy | examples=she was easily excited; was easily confused. This sense conveys "with ease, without difficulty".
2. easily%4:02:06:: | definition=without question | examples=easily the best book she's written. This is an absolute superlative usage, like "undoubtedly".
3. easily%4:02:05:: | definition=indicating high probability; in all likelihood | synonyms=well | examples=I might well do it; a mistake that could easily have ended in disaster. This sense indicates probability, like "it could easily happen".

In the medical context, "spread easily" means the cancer spreads with little difficulty, i.e., it readily metastasizes. It's not about probability (sense 3) or without question (sense 2). It is about the ease of spreading. The example from sense 1: "was easily confused" matches "spread easily": the cancer is easily spread. So sense 1 is the best fit.

Thus, the answer is sense index 1.

format: unknown

native_finish_reason: stop

provider: StreamLake

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: other
Target surface form: other
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=other%3:00:00:: | definition=not the same one or ones already mentioned or implied; - the White Queen | examples=today isn't any other day; the construction of highways and other public works
2. sense_key=other%5:00:00:past:00 | definition=recently past | examples=the other evening
3. sense_key=other%5:00:02:past:00 | definition=belonging to the distant past | synonyms=early, former | examples=the early inhabitants of Europe; former generations
4. sense_key=other%5:00:00:strange:00 | definition=very unusual; different in character or quality from the normal or expected; - Lance Morrow | examples=a strange, other dimension...where his powers seemed to fail

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to perform Word Sense Disambiguation for the word "other" in the given context. We must choose the best indexed sense among the four provided.

Let's analyze the context: "Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to <t>other</t> parts of the body)". Here, "other" refers to additional parts of the body besides the original site. It means "different parts" or "not the same one already mentioned". Sense 1: "not the same one or ones already mentioned or implied". The example given: "today isn't any other day; the construction of highways and other public works" fits because "other public works" means additional ones not already mentioned. In the medical context, "other parts of the body" means parts not already affected by the cancer. The sense is "not the same one already mentioned". The other senses: sense 2 (recently past) doesn't fit; sense 3 (distant past) doesn't fit; sense 4 (very unusual, different in character) doesn't fit, as it refers to strange or abnormal, which is not the case here.

Therefore, the correct sense is sense index 1.

Now, format as JSON: {"sense_index": 1}

provider: Baidu


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: parts
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other <t>parts</t> of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to choose the best sense for "parts" in the context: "has spread, or is likely to spread easily, to other parts of the body". The target lemma is part, surface form parts. The context is about cancer spreading to other parts of the body. "Parts of the body" refers to anatomical regions or locations. Let's check candidate senses:

1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript. This is abstract: part as a component of a whole, but not necessarily spatial. "Parts of the body" is spatial, physical locations.

2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together. This is for artifacts (human-made). Body parts are not artifacts.

3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite. This is for natural objects, like rivers, rocks. Body parts are parts of a living organism, which might be considered natural objects. However, the definition says "a portion of a natural object". The human body could be seen as a natural object. But is there a more specific sense? Let's check others.

4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part. Not relevant.

5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world. This is about regions, areas, locations. "Parts of the body" could be regions of the body. Example: "religions in all parts of the world" maps to "parts of the body" as spatial locations. This seems plausible.

6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | not relevant.

7. sense_key=part%1:09:01:: | definition=an actor's portrayal... not relevant.

8. sense_key=part%1:21:00:: | assets... share, not relevant.

9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company. This is for conceptual divisions, like parts of an exam, parts of a company. Could "parts of the body" be seen as divisions of the body? Possibly, but body parts are natural physical parts, not conceptual divisions. The example "the written part of the exam" suggests a functional division.

10. sense_key=part%1:08:01:: | hair parting, not relevant.

11. sense_key=part%1:10:00:: | music, not relevant.

12. sense_key=part%1:04:03:: | contribution, not relevant.

The two most relevant seem to be 3 and 5. Sense 3: "a portion of a natural object" with example "they analyzed the river into three parts". The body is a natural object. Sense 5: "the extended spatial location of something" with example "religions in all parts of the world". In the context, "spread to other parts of the body" refers to spreading to different regions/locations within the body. It is spatial. The phrase "parts of the body" is common, and WordNet likely has a specific sense for body parts? Actually, there is a sense "body part" as a separate noun. But here the word is "part". In WordNet, the sense "region" is often used for geographical areas. The example "religions in all parts of the world" is about locations. For the body, "other parts of the body" means other anatomical regions. So sense 5 (region) seems appropriate. Sense 3 (piece of a natural object) might be used for a piece of a physical object, like a piece of granite. But "parts of the body" doesn't imply the body is chopped into pieces; it's about spatial locations. I'll go with sense 5.

Thus, the best indexed sense is 5.

provider: Fireworks


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the <t>body</t>), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to perform word sense disambiguation for the target word "body" in the given context. The context is about the drug Alimta and its use in treating cancer. Specifically, the sentence containing the target is: "Alimta is used together with cisplatin when the cancer is unresectable and malignant (has spread, or is likely to spread easily, to other parts of the body)". So "body" here refers to the human body, the physical structure of a person. We need to select the best indexed sense from the provided list.

Let's examine the candidate senses:
1. the entire structure of an organism (an animal, plant, or human being) - this fits perfectly. The cancer spreads to other parts of the human body.
2. a group of persons - not relevant.
3. a dead body - not relevant.
4. an individual 3-dimensional object that has mass - could be a celestial body, not relevant.
5. the body excluding the head and neck and limbs (torso) - not appropriate; the context refers to the whole body, not just the torso.
6. a collection of particulars considered as a system - like "body of law", not relevant.
7. property of holding together and retaining its shape - consistency, not relevant.
8. central message of a communication - not relevant.
9. the main mass of a thing - not relevant.
10. resonating chamber in a musical instrument - not relevant.
11. external structure of a vehicle - not relevant.

So the best sense is sense_index 1. The instruction says: "Do not answer with a WordNet sense key. Return only a JSON object exactly like {"sense_index": 3}." So we output {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in <t>patients</t> who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are given the target lemma "patient" and the surface form "patients". The context is about Alimta, a cancer treatment, and mentions "patients" who have certain types of cancer and have or have not received chemotherapy. Clearly, it refers to people receiving medical care. Sense 1 is "a person who requires medical care" with example "the number of emergency patients has grown rapidly". Sense 2 is a linguistic/semantic role, completely irrelevant here. So the best sense is sense 1. Return as JSON.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicines
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (<t>medicines</t> for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are asked to disambiguate "medicines" in the context: "Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable ... in patients who have not received chemotherapy (<t>medicines</t> for cancer) before ...". The target is "<t>medicines</t>" inside the parentheses. The context says: "chemotherapy (<t>medicines</t> for cancer)". So it's referring to drugs used to treat cancer. Sense 2 is: (medicine) something that treats or prevents or alleviates the symptoms of disease, synonyms medication, medicament, medicinal drug. That fits perfectly. Sense 1 is medical specialty, sense 3 is practice of medicine, sense 4 is punishment. So clearly sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for <t>cancer</t>) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are asked to choose the best sense for "cancer" in the context. The target surface form is "cancer" and the lemma is "cancer". The context is about Alimta, a medicine used to treat two types of cancer: pleural mesothelioma and non-small cell lung cancer. The sentence with the tag "<t>cancer</t>" is: "in patients who have not received chemotherapy (medicines for <t>cancer</t>) before". So the word "cancer" here refers to the disease. We have five candidate senses. Sense 1 is "any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream". That fits perfectly: the disease cancer. The other senses are astrological (2, 3, 4) and a genus of crab (5). Clearly, sense 1 is correct. Return JSON: {"sense_index": 1}.

provider: Alibaba


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: advanced
Target surface form: advanced
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before <t>advanced</t> or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=advanced%5:00:00:precocious:00 | definition=farther along in physical or mental development | examples=the child's skeletal age was classified as `advanced'; children in the advanced classes in elementary school read far above grade average
2. sense_key=advanced%5:00:00:late:02 | definition=comparatively late in a course of development | examples=the illness had reached an advanced stage; an advanced state of exhaustion
3. sense_key=advanced%5:00:00:progressive:01 | definition=ahead of the times | synonyms=forward-looking, innovative, modern | examples=the advanced teaching methods; had advanced views on the subject
4. sense_key=advanced%5:00:02:high:02 | definition=at a higher level in training or knowledge or skill | examples=an advanced degree; an advanced text in physics
5. sense_key=advanced%5:00:00:high-tech:00 | definition=ahead in development; complex or intricate | synonyms=sophisticated | examples=advanced technology; a sophisticated electronic control system
6. sense_key=advanced%5:00:00:late:00 | definition=far along in time | synonyms=ripe | examples=a man of advanced age; advanced in years
7. sense_key=advanced%5:00:00:civilized:00 | definition=(of societies) highly developed especially in technology or industry | examples=advanced societies; an advanced country technologically
8. sense_key=advanced%5:00:00:front:00 | definition=situated ahead or going before | synonyms=advance, in advance | examples=an advance party; at that time the most advanced outpost was still east of the Rockies

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are given a target lemma "advanced" with context: "in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer". The phrase is "advanced or metastatic non-small cell lung cancer". Here "advanced" describes the state of the cancer. It means the cancer is at an advanced stage of development. This matches sense 2: "comparatively late in a course of development" with example "the illness had reached an advanced stage". That sense is about being late in development, like a disease. Sense 1 is about physical/mental development (precocious). Sense 3 is about being innovative/modern. Sense 4 is about higher level in training/knowledge. Sense 5 is about high-tech/complex. Sense 6 is about age. Sense 7 is about societies. Sense 8 is about spatial position (advance party). So clearly sense 2 fits best. The instruction says return only a JSON object with sense_index. The sense list is numbered 1 to 8. So answer is 2.

provider: SiliconFlow


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cell
Target surface form: cell
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=cell%1:06:03:: | definition=any small compartment | examples=the cells of a honeycomb
2. sense_key=cell%1:03:00:: | definition=(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
3. sense_key=cell%1:06:00:: | definition=a device that delivers an electric current as the result of a chemical reaction | synonyms=electric cell
4. sense_key=cell%1:14:00:: | definition=a small unit serving as part of or as the nucleus of a larger political movement | synonyms=cadre
5. sense_key=cell%1:06:04:: | definition=a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver | synonyms=cellular telephone, cellular phone, cellphone, mobile phone
6. sense_key=cell%1:06:02:: | definition=small room in which a monk or nun lives | synonyms=cubicle
7. sense_key=cell%1:06:01:: | definition=a room where a prisoner is kept | synonyms=jail cell, prison cell

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are given the target lemma "cell" and surface form "cell" within the context: "advanced or metastatic non-small <t>cell</t> lung cancer that is not affecting the squamous cells." The target word is "cell" as part of "non-small cell lung cancer." The context mentions cancer, specifically "non-small cell lung cancer" and "squamous cells." This clearly refers to biological cells, i.e., the basic structural and functional unit of living organisms. The definition for sense 2 is: "(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals." This matches perfectly. Other senses: 1 is about compartments like honeycomb; 3 is electric cell; 4 is political; 5 is mobile phone; 6 is monk's room; 7 is prison cell. None fit. Thus, sense_index is 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given a target word "affect" with surface form "affecting" in a specific context. The context is about a drug Alimta used to treat cancer, and the sentence states: "advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells." So, here "affecting" means the cancer is not impacting or involving the squamous cells. The sense needed is about having an effect or influence on something. Let's evaluate the candidate senses:

1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
   - This is a general sense of having an effect. Could fit.

2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
   - This is more about physically acting on something, like a medicine affecting a body part. The cancer is not exactly acting physically on squamous cells in the same way a medicine acts on heart rate. The cancer is more "involving" or "impacting" those cells. However, cancer affecting cells could be physical. But note that the context says "cancer that is not affecting the squamous cells" meaning the cancer does not involve those cells. This sense might also be plausible.

3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
   - This sense includes "involve" as a synonym, and the example "This new ruling affects your business" suggests a connection or involvement. In the medical context, "cancer not affecting squamous cells" likely means the cancer does not involve those cells. This sense seems very fitting: "connect closely and often incriminatingly" aligns with cancer involving certain cell types. The synonym "involve" is key. This is a specific sense of affect meaning to involve or concern.

4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
   - Clearly not relevant.

5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd
   - Emotional impact is not relevant here.

Now, between senses 1, 2, and 3, we need to pick the best. Sense 1 is broad: "have an effect upon". Sense 2 is more physical: "act physically on". Sense 3 is "connect closely and often incriminatingly" with synonym "involve". In medical contexts, when describing cancer subtypes, they often use "affecting" to mean "involving" or "arising in" specific cells. For example, "squamous cell carcinoma affects squamous cells" means it involves those cells. So sense 3 with "involve" as a direct synonym seems most precise. Sense 1 could work, but it's very generic. Sense 2 emphasizes physical action, which is also plausible, but the gloss for sense 3 explicitly includes "involve" which is commonly used in medical descriptions. Let's check WordNet for these senses. The sense_key format: affect%2:30:00:: (sense 1) is a very general sense. Sense 3 (affect%2:42:00::) is often used in legal/business contexts to mean "to pertain to or involve". In medical writing, "affect" meaning "to involve or attack (a part of the body)" is common. For example, "the disease affects the lungs." That specific medical meaning is often listed in dictionaries. WordNet's sense 3 with definition "connect closely and often incriminatingly" might be capturing this idea of involvement, albeit with a legalistic tone. But the example "This new ruling affects your business" is about a ruling involving your business. Similarly, cancer involving squamous cells. I think sense 3 is the best match.

Therefore, I'll choose sense_index 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given a target lemma "use", surface form "used", and the context. The target is highlighted as <t>used</t> in the sentence: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

We need to choose the best indexed sense from the candidates. The context is medical/pharmaceutical: Alimta (a medication) is used for treating cancer. The target "used" refers to the purpose/application of the drug. So the sense is about employing something for a particular purpose. Let's examine the candidates:

1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

In the context, "Alimta is used in combination with cisplatin..." clearly means that Alimta is employed or utilized for a medical purpose. It is not about consuming (sense 2), using up (sense 3), exploiting (sense 4), practicing (sense 5), or the habitual past tense construction (sense 6, which would be "used to" but here it's "is used", passive voice). So sense 1 fits best: put into service, employ for a purpose.

Thus, the best indexed sense is 1.

Return JSON: {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content: We are asked to disambiguate "patient" in the given context. The target lemma is "patient", the surface form is "patients". The context is a medical text from the EMA (European Medicines Agency) about the drug Alimta. The sentence: "Alimta is used in combination with cisplatin in patients who have not been treated before..." The target word is "patients". Clearly, this refers to people receiving medical treatment. Sense 1: a person who requires medical care. Sense 2: a linguistic semantic role. The context is medical, so sense 1 is correct. Return JSON with sense_index:

provider: DigitalOcean


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treated
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to perform word sense disambiguation for the target lemma "treat" with surface form "treated" in the given context. We need to choose the single best indexed sense among 8 candidates. The context is about a medicine Alimta used to treat cancer. The specific sentence: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past." The word "treated" refers to patients who haven't received treatment before. In medical context, "treat" means providing medical care, therapy, or intervention. Looking at the senses:

1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Sense 3 is explicitly about providing treatment for, especially medical: "provide treatment for", synonyms "care for", examples: "The doctor treated my broken leg; The nurses cared for the bomb victims". This perfectly matches the medical context where patients are treated with chemotherapy. Sense 2 is about subjecting to a process or treatment, but it's more about processing things like cheese or hair, not medical care. Sense 3 is the most direct. Also, the phrase "patients who have not been treated before" clearly means they haven't received medical treatment. So index 3 is correct.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given a sentence: "The medicine can only be obtained with a prescription." The target word is "patients" in the context of the whole passage. The word appears in the phrase: "in patients who have not received chemotherapy... and on its own in patients who have received another type of chemotherapy in the past." The candidate senses are: sense 1 (a person who requires medical care) and sense 2 (the semantic role of an entity affected by the action). Clearly, in this medical context, "patients" refers to people receiving medical treatment. Sense 1 fits perfectly. Sense 2 is a linguistic term, not applicable here. So the best indexed sense is 1.

Now, the output must be a JSON object with the key "sense_index" and an integer value. So: {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to perform word sense disambiguation for the target word "type" in the given context. The context is: "...and on its own in patients who have received another type of chemotherapy in the past." We need to choose the best indexed sense from the candidates.

Let's examine the context: "another type of chemotherapy" – here, "type" refers to a category or kind of chemotherapy. It's about a subdivision of a particular kind of thing. So sense 1 seems appropriate: "a subdivision of a particular kind of thing". The example for sense 1: "what type of sculpture do you prefer?" fits with this usage.

Other senses: sense 2 refers to a person (character), sense 3 is biology-specific, sense 4 is printed characters, sense 5 is tokens of a symbol, sense 6 is a metal block for printing. None of these fit the context of a type of chemotherapy. So the best index is 1.

Thus, the JSON output: {"sense_index":


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to choose the best sense for "past" in the context: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past." The target surface form is "past".

Candidate senses:
1. the time that has elapsed (synonyms: past times, yesteryear; example: forget the past)
2. a earlier period in someone's life (especially one that they have reason to keep secret) (example: reporters dug into the candidate's past)
3. a verb tense that expresses actions or states in the past (synonym: past tense)

In the context, "past" is used in the phrase "in the past", referring to a time before the present. It means previously, or in a time that has already elapsed. The sentence is contrasting patients who have not been treated before with those who have received chemotherapy previously. So "past" refers to a general time before now, not specifically a verb tense or a secret earlier period. Sense 1 is the most appropriate: the time that has elapsed. Sense 2 is too specific and carries a connotation of secrecy, which is not implied. Sense 3 is a grammatical term, irrelevant here.

Thus, sense index 1 is correct.

provider: AtlasCloud


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to disambiguate "medicine" in the context: "The <t>medicine</t> can only be obtained with a prescription." The context is about Alimta, a drug used to treat cancer. It mentions "anticancer medicine" and "chemotherapy (medicines for cancer)". The target word "medicine" refers to the drug itself, Alimta, which is a medication. Looking at the candidate senses:
1. medical specialty (the branch of science)
2. medication, medicament, medicinal drug (something that treats or prevents disease)
3. practice of medicine (the profession)
4. punishment (like "take your medicine")

Clearly, in this context, "medicine" means the drug (Alimta) that requires a prescription. So sense 2 is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given: Target lemma: only, target surface form: only. Context: "The medicine can <t>only</t> be obtained with a prescription." So the sentence is: "The medicine can only be obtained with a prescription."

We need to choose the best indexed sense from the list. Let's analyze each sense:

1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

In the context, "only" modifies "can be obtained". The meaning is that the medicine can be obtained exclusively with a prescription, i.e., it requires a prescription and nothing else suffices. It implies a restriction: the sole way to obtain it is with a prescription. So "only" here means "exclusively" or "solely", indicating that without a prescription, it cannot be obtained. It does not mean "merely" or "simply" (sense 1) because that would downplay the action ("merely obtained"), which doesn't fit. It is about the condition of prescription being the only way.

Sense 2: "without any others being included or involved" and synonyms: entirely, exclusively, solely, alone. Example: "was entirely to blame" where the blame is solely on that person. Our sentence: "can only be obtained with a prescription" means "can be obtained exclusively with a prescription", which fits the idea of exclusivity.

Sense 1: "and nothing more" like "I was merely asking" implies that it was just asking, nothing more serious. That doesn't fit here because we're not saying the action of obtaining is merely that, but that the condition is exclusive.

Sense 6: "never except when" (only if, only when) is similar but it's a conjunction. In this sentence, "only" is an adverb modifying "can be obtained", not a conjunction. It doesn't introduce a condition clause per se. "The medicine can only be obtained with a prescription" is equivalent to "The medicine can only be obtained if you have a prescription." But the structure here uses "only" as an adverb, not "only if" as a conjunction. However, the meaning is basically "only with a prescription" implying the condition. But sense 6 defines "only" as "never except when" and gives synonyms "only if, only when", which are used as subordinators. In the sentence, "only" is not directly "only if"; it's just "only" modifying the verb phrase. Typically, "only" in such contexts is an adverb meaning "solely" or "exclusively". For example, in "You can only enter with a ticket", "only" is an adverb. So sense 2 seems more directly applicable.

Sense 2 includes the synonym "exclusively" and "solely". In the sentence, it's "only" meaning that the prescription is the exclusive means of obtaining it. So I'd pick sense 2.

Check others: Sense 3 is about a final result that is unexpected (only to find...). Not this. Sense 4: "in the final outcome" like "These news will only make you more upset" meaning the ultimate effect. Not this. Sense 5: "except that" as in "It was the same story; only this time..." Not this. Sense 7: "as recently as" - "only an hour ago" - not this.

Thus sense 2 is the best.

So answer: {"sense_index": 2}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: obtain
Target surface form: obtained
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to perform Word Sense Disambiguation for the target word "obtained" in the given context. The target surface form is "obtained" and the lemma is "obtain". We need to choose the best indexed sense from the three candidates.

First, understand the context: The target sentence is: "The medicine can only be obtained with a prescription."

So, we are talking about obtaining a medicine. The meaning is that you can only get the medicine if you have a prescription.

Now, evaluate the three candidate senses:

1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
This sense means to acquire or get physical possession of something. It fits well: obtaining a medicine with a prescription means getting possession of the medicine.

2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
This sense is about receiving a treatment or something abstract like an expression or review. The examples show "find expression", "receive an interpretation", "His movie received a good review". It is not about physically obtaining an object. In the context, we are talking about getting a physical medicine, not receiving a treatment in an abstract sense. The medicine is a physical item that you obtain, not a treatment that you receive in the sense of "undergo". However, one might argue that "obtained with a prescription" could mean "received treatment" but the phrasing "obtained with a prescription" strongly suggests possession: you go to a pharmacy and get the medicine. Also, the synonyms include "receive", "get", but the definition says "receive a specified treatment (abstract)". The context is concrete: the medicine, which is a tangible thing. So sense 2 is less appropriate.

3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds
This sense is completely unrelated. It means "holds true" or "prevails". In the context, "The medicine can only be obtained with a prescription" does not mean the medicine is valid or holds with a prescription. It means you can get it. So sense 3 is clearly wrong.

Thus, sense 1 is the best match: "come into possession of". The example "How did you obtain the visa?" parallels obtaining a medicine: both are about getting something tangible (visa document, medicine). So I'll select sense 1.

Now, format as JSON: {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prescription
Target surface form: prescription
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
4. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are asked to choose the best sense for "prescription" in the given context. Let's analyze the context: "The medicine can only be obtained with a prescription." This refers to the requirement of a written instruction from a doctor to obtain the medicine. The candidate senses:

1. Directions prescribed beforehand; authoritative rules. Not relevant.
2. A drug available only with written instructions. This is a noun referring to the drug itself, not the document. Example: "he told the doctor that he had been taking his prescription regularly" – here, "prescription" means the medicine. But in the context, "with a prescription" means the document/instruction, not the drug itself. "Obtained with a prescription" means you need a written order from a doctor.
3. Written instructions for an optician on lenses. Not relevant.
4. Written instructions from a physician to a druggist concerning the form and dosage of a drug. This matches exactly: the document that allows you to obtain the medicine.

So sense 4 is the best. The phrase "with a prescription" means using a written order from a doctor. Sense 4 defines that. Sense 2 is the drug itself, but you don't obtain the medicine with a drug; you obtain it with a written order. So answer is sense 4.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
We are given the target lemma "use" and the surface form "used" in the context. The context is about Alimta, a medicine used to treat cancer. We need to disambiguate the sense of "used" in the specific sentence: "How is Alimta used?" But note that the target is the whole lemma "use" and the surface form "used" appears in several places. The prompt says "Target surface form: used" and the context includes "How is Alimta <t>used</t>?" So the specific instance is the one with the tag. So we need to choose the sense for that occurrence: "How is Alimta used?" meaning in what manner or for what purpose is it employed.

Now, look at the candidate senses:

1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home

2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely

3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions

4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections

5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion

6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

We are to choose the best indexed sense for the target word in context. The sentence is "How is Alimta used?" This is a medical question about the method of administering a drug. It means "in what way is Alimta utilized/employed?" Or more specifically, how is it administered? But the sense is about employing something for a purpose.

Sense 1: "put into service; make work or employ for a particular purpose or for its inherent or natural purpose." That fits perfectly: Alimta is a medicine put into service to treat cancer. The question "How is Alimta used?" asks about its administration or application. Synonyms include "utilize, utilise, apply, employ." This is the most common sense of "use" for objects.

Sense 2: "take or consume (regularly or habitually)" with example "She uses drugs rarely." This is for consumption of substances, especially drugs, but it emphasizes habitual use. The question "How is Alimta used?" is not about habitual consumption but about the manner of administration. The context says "How is Alimta used?" and then explains that it should be given under supervision. It might be about the method of administration. Sense 2 is specific to drugs, but it implies regular/habitual use. The question is not about frequency but about the procedure.

Sense 3: "use up, consume fully" like "expend." That doesn't fit; Alimta isn't being used up entirely.

Sense 4: "seek or achieve an end by using to one's advantage" like using influential friends. Not applicable.

Sense 5: "avail oneself to" like "apply a principle" or "practice a religion." Doesn't fit.

Sense 6: "habitually do something (use only in the past tense)" like "used to call." This is the "used to" auxiliary, not the main verb "use". Here it's "used" as past participle of "use" in passive voice: "is used". So not sense 6.

So sense 1 is the clear winner. Sense 2 might be tempting because it's about drugs, but "use" in medical contexts for drugs can have both senses. However, the question "How is Alimta used?" is asking about the method of employment, not about habitual consumption. For example, "How is insulin used?" would mean how to inject it, not "how does one consume insulin regularly." Also, the synonyms for sense 2 are "habituate," and the example is "She uses drugs rarely," which is about the act of taking drugs. But I think sense 1 covers the general employment of a medicine: "apply or employ for a particular purpose." Indeed, medical English often uses "use" in sense 1 for drugs. For instance, "This medicine is used to treat headaches" is sense 1. So sense 1 is best.

Thus, we pick sense index 1.

Return JSON: {"sense_index": 1}