[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: affect
Target surface form: affecting
Context:
What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not <t>affecting</t> the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past.

Candidate senses:
1. sense_key=affect%2:30:00:: | definition=have an effect upon | synonyms=impact, bear upon, bear on, touch on, touch | examples=Will the new rules affect me?
2. sense_key=affect%2:29:00:: | definition=act physically on; have an effect upon | examples=the medicine affects my heart rate
3. sense_key=affect%2:42:00:: | definition=connect closely and often incriminatingly | synonyms=involve, regard | examples=This new ruling affects your business
4. sense_key=affect%2:32:00:: | definition=make believe with the intent to deceive | synonyms=feign, sham, pretend, dissemble | examples=He feigned that he was ill; He shammed a headache
5. sense_key=affect%2:37:00:: | definition=have an emotional or cognitive impact upon | synonyms=impress, move, strike | examples=This child impressed me as unusually mature; This behavior struck me as odd

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

The word "affecting" in this medical context describes the cancer acting upon or having a physical effect on the squamous cells. Sense 2 ("act physically on; have an effect upon") is the best match because it captures the physical/biological impact of the disease on tissue, similar to the provided example of medicine affecting heart rate. The cancer either is or is not affecting (acting upon) the squamous cells.

reasoning_content:
The target word is "affecting" in the context of medical information about Alimta cancer treatment. Let me look at the sentence:

"advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells"

In this medical context, "affecting" is being used to describe whether the cancer is impacting or acting upon the squamous cells. The meaning is about whether the cancer is having an effect on or impacting the squamous cells.

Let me examine each sense:

1. "have an effect upon" - This matches well. The cancer is not having an effect upon the squamous cells. Synonyms: impact, bear upon, bear on, touch on, touch. Example: "Will the new rules affect me?" - This is about rules having an effect on someone.

2. "act physically on; have an effect upon" - This also matches. The cancer acting physically on cells would fit. Example: "the medicine affects my heart rate" - This is about a substance having a physical effect.

3. "connect closely and often incriminatingly" - This doesn't fit the medical context.

4. "make believe with the intent to deceive" - This doesn't fit at all (pretend/feign).

5. "have an emotional or cognitive impact upon" - This is about emotional or cognitive impact, not physical impact on cancer.

Between senses 1 and 2:
- Sense 1: "have an effect upon" - general effect
- Sense 2: "act physically on; have an effect upon" - physical action

In the medical context of cancer affecting cells, sense 2 ("act physically on; have an effect upon") seems more appropriate because we're talking about a disease physically affecting tissue/cells, similar to how "the medicine affects my heart rate" in the example.

However, sense 1 is also a viable interpretation. But sense 2 is more specific to the physical/medical context where something acts upon something else.
Sense 2 is the strongest match here. The physical nature of cancer acting on cellular tissue aligns with the sense that emphasizes physical action, and the parallel to how medications affect bodily systems reinforces this interpretation. My answer is sense index 2.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is <t>used</t> in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context describes Alimta being employed or put into service for the purpose of treating cancer (in combination with cisplatin). This matches sense 1: "put into service; make work or employ for a particular purpose or for its inherent or natural purpose," which is exemplified by phrases like "use your head" and "use Spanish at home" where the word means to employ something for a specific purpose.

finish_reason: stop

role: assistant

reasoning_content:
Let me analyze the context to determine which sense of "use" is most appropriate.

The context is: "Alimta is used in combination with cisplatin in patients who have not been treated before..."

Looking at the sentence structure and meaning:
- Alimta is being employed/applied for the purpose of treating cancer
- It's describing what the medicine is administered for
- The meaning is "to employ for a particular purpose"

Let me examine each sense:

1. sense_key=use%2:34:01:: "put into service; make work or employ for a particular purpose or for its inherent or natural purpose" - This fits well. The medicine is being put into service/employed for the purpose of treating cancer.

2. sense_key=use%2:34:02:: "take or consume (regularly or habitually)" - This doesn't fit. We're not talking about consuming/taking the medicine habitually in this context.

3. sense_key=use%2:34:00:: "use up, consume fully" - This doesn't fit. We're not talking about consuming it fully.

4. sense_key=use%2:41:14:: "seek or achieve an end by using to one's advantage" - This has a manipulative connotation that doesn't apply here.

5. sense_key=use%2:41:04:: "avail oneself to" - This could work, but it's not as precise as sense 1.

6. sense_key=use%2:41:03:: "habitually do something (use only in the past tense)" - This is specifically for past tense habitual actions like "used to," which isn't the case here.

The best sense is clearly #1 (use%2:34:01::), which means "put into service; make work or employ for a particular purpose." The medicine is being employed/used for the purpose of treating cancer.

type: thinking

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{
  "sense_index": 1
}
```

The target word "patients" in this medical context refers to people who require medical care (specifically those being treated for cancer with Alimta). This is the standard lexical sense of "patient" as a noun denoting a person receiving medical treatment, not the grammatical/semantic role sense.

reasoning_content:
Let me analyze the target word "patients" in this context.

The sentence is: "Alimta is used in combination with cisplatin in <t>patients</t> who have not been treated before..."

Now let me examine the two candidate senses:

1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
   - This refers to a person who requires medical care, someone who is being treated for a disease or condition
   - This is the common meaning of "patient" in a medical context

2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role
   - This is a grammatical/semantic role definition
   - This refers to the thematic role in linguistics

In the given context "Alimta is used in combination with cisplatin in patients who have not been treated before", the word "patients" clearly refers to people who require medical care - specifically people being treated for cancer with Alimta.

This is sense 1: a person who requires medical care.

The answer should be: {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treated
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been <t>treated</t> before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

The context is clearly medical/therapeutic. The sentence discusses patients who have not been treated (medically) before with chemotherapy. Sense 3 "provide treatment for" with its example "The doctor treated my broken leg" is the direct parallel—providing medical care or therapy to remedy a medical condition. This matches perfectly with the medical treatment scenario described in the passage about treating cancer patients with Alimta.

reasoning_content:
Let me analyze the context to determine which sense of "treat" is being used.

The sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

In this context, "treated" refers to providing medical treatment/therapy for a medical condition (cancer). The context is clearly about medical treatment - the drug Alimta is used to treat cancer, and the sentence is discussing patients who have not been given chemotherapy before (i.e., not been treated for cancer yet).

Let me evaluate each sense:

1. sense_key=treat%2:41:00:: - "interact in a certain way" - Not applicable here. This is about how to interact with someone.

2. sense_key=treat%2:30:01:: - "subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition" - This could work, but it's more about processing/preparing something.

3. sense_key=treat%2:29:00:: - "provide treatment for" - This is clearly the right one! Examples include "The doctor treated my broken leg" which is directly parallel to using Alimta to treat cancer. The synonyms include "care for" which fits perfectly with medical treatment.

4. sense_key=treat%2:32:00:: - "act on verbally or in some form of artistic expression" - Not applicable.

5. sense_key=treat%2:40:00:: - "provide with a gift or entertainment" - Not applicable.

6. sense_key=treat%2:34:00:: - "provide with choice or abundant food or drink" - Not applicable.

7. sense_key=treat%2:32:03:: - "engage in negotiations in order to reach an agreement" - Not applicable.
8. sense_key=treat%2:31:00:: - "regard or consider in a specific way" - Not applicable.

The answer is sense #3: "provide treatment for." This directly matches the medical context where patients receive therapeutic intervention for cancer, just as a doctor treats a broken leg.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: patient
Target surface form: patients
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in <t>patients</t> who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=patient%1:18:00:: | definition=a person who requires medical care | examples=the number of emergency patients has grown rapidly
2. sense_key=patient%1:10:00:: | definition=the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause | synonyms=affected role, patient role

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context clearly refers to "patients" as people who require medical care for cancer treatment. The text discusses Alimta being used in patients with specific medical conditions and treatment histories, which aligns with the definition "a person who requires medical care" rather than a linguistic semantic role.

reasoning_content:
Let me analyze the context to determine which sense of "patient" (patients) is being used.

The sentence is: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

The two candidate senses are:

1. Sense 1 (patient%1:18:00::): "a person who requires medical care" - Example: "the number of emergency patients has grown rapidly"

2. Sense 2 (patient%1:10:00::): "the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause" - Synonyms: affected role, patient role

In the context given, "patients" refers to people who are receiving medical treatment for cancer. The context is clearly about medical treatment - Alimta is used to treat certain types of cancer in patients (people with cancer who need medical care).

Sense 1 is the straightforward interpretation: "patients" = people who require medical care (specifically, cancer patients in this case).

Sense 2 is a linguistic/grammatical sense referring to the semantic role of an entity in a clause. This is not what's being used here - the text isn't discussing grammar or linguistic roles.

The correct answer is Sense 1, which is the most straightforward and contextually appropriate. The word "patients" in this medical text clearly refers to people who require medical care.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: type
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another <t>type</t> of chemotherapy in the past. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The word "type" in this context refers to a "subdivision of a particular kind of thing" - specifically, a kind or category of chemotherapy. The phrase "another type of chemotherapy" is asking about a different category or kind of chemotherapy treatment, which directly parallels the given example "what type of sculpture do you prefer?"

reasoning_content:
Let me analyze the context for the word "type" in this passage.

The sentence reads: "Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past."

Here, "type" is being used to refer to a category or kind of chemotherapy. The context is asking "what type of chemotherapy" - meaning what kind or category of chemotherapy treatment.

Let me examine the candidate senses:

1. "a subdivision of a particular kind of thing" - with the example "what type of sculpture do you prefer?" - This is clearly about kinds or categories of things. This fits perfectly with the context where we're talking about different kinds/categories of chemotherapy.

2. "a person of a specified kind (usually with many eccentricities)" - This is about people with certain characteristics. Not relevant here.

3. "(biology) the taxonomic group whose characteristics are used to define the next higher taxon" - This is a specific biological/taxonomic term. Not relevant here.

4. "printed characters" - About typography/printing. Not relevant.

5. "all of the tokens of the same symbol" - About linguistics/typography. Not relevant.

6. "a small metal block bearing a raised character on one end" - About physical printing blocks. Not relevant.

The best match is clearly sense 1, which defines "type" as "a subdivision of a particular kind of thing" with the example "what type of sculpture do you prefer?" This is the exact same usage pattern - asking about what type/kind/category of something.

The answer should be sense_index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: past
Target surface form: past
Context:
Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the <t>past</t>. The medicine can only be obtained with a prescription.

Candidate senses:
1. sense_key=past%1:28:00:: | definition=the time that has elapsed | synonyms=past times, yesteryear | examples=forget the past
2. sense_key=past%1:28:01:: | definition=a earlier period in someone's life (especially one that they have reason to keep secret) | examples=reporters dug into the candidate's past
3. sense_key=past%1:10:00:: | definition=a verb tense that expresses actions or states in the past | synonyms=past tense

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The target word "past" in the phrase "in the past" refers to the time that has already elapsed or gone by. The sentence indicates that these patients received chemotherapy at an earlier time before the present. This matches sense 1 ("the time that has elapsed"), not sense 2 (which is about a personal biographical history) or sense 3 (which concerns grammar).

reasoning_content:
Let me analyze the context to determine which sense of "past" is being used.

The sentence is: "...and on its own in patients who have received another type of chemotherapy in the past."

Here, "in the past" means "previously" or "before now" - it's referring to an earlier time period when these patients received chemotherapy.

Let me examine each sense:

1. **sense 1: "the time that has elapsed" | definition with examples "forget the past"**
   - This refers to the general time that has gone by, the period of time before the present
   - Synonyms: past times, yesteryear
   - The phrase "in the past" fits this meaning - it refers to the time period that has already happened

2. **sense 2: "a earlier period in someone's life (especially one that they have reason to keep secret)" | example "reporters dug into the candidate's past"**
   - This is more specific to personal history or biographical information
   - It's used with the connotation of something potentially hidden or controversial
   - This doesn't fit the medical context here

3. **sense 3: "a verb tense that expresses actions or states in the past"**
   - This is a grammatical sense
   - This doesn't apply here since "past" is being used as a noun, not referring to grammar

The context is: patients who have received another type of chemotherapy "in the past"

This clearly means "at an earlier time" or "previously" - referring to the period of time before the present moment. This is sense 1, which is about the general time that has elapsed, not about someone's personal history (sense 2) or grammar (sense 3).

The answer is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: medicine
Target surface form: medicine
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The <t>medicine</t> can only be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=medicine%1:09:00:: | definition=the branches of medical science that deal with nonsurgical techniques | synonyms=medical specialty
2. sense_key=medicine%1:06:00:: | definition=(medicine) something that treats or prevents or alleviates the symptoms of disease | synonyms=medication, medicament, medicinal drug
3. sense_key=medicine%1:04:00:: | definition=the learned profession that is mastered by graduate training in a medical school and that is devoted to preventing or alleviating or curing diseases and injuries | synonyms=practice of medicine | examples=he studied medicine at Harvard
4. sense_key=medicine%1:04:02:: | definition=punishment for one's actions | synonyms=music | examples=you have to face the music; take your medicine

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

The target word "medicine" in the context refers to Alimta, a pharmaceutical drug used to treat cancer. The sentence "The medicine can only be obtained with a prescription" clearly indicates that "medicine" is being used to mean a drug or medication that treats disease, which corresponds to sense 2: "something that treats or prevents or alleviates the symptoms of disease" with synonyms medication, medicament, medicinal drug.

reasoning_content:
Looking at the context, the passage is about Alimta, which is a cancer drug. The sentence "The medicine can only be obtained with a prescription" is referring to the drug/medication being discussed.

Let me analyze each sense:

1. sense_key=medicine%1:09:00:: - "the branches of medical science that deal with nonsurgical techniques" - This is about fields of medical science, not applicable here.

2. sense_key=medicine%1:06:00:: - "(medicine) something that treats or prevents or alleviates the symptoms of disease" with synonyms "medication, medicament, medicinal drug" - This is the sense referring to a drug or medication that treats disease. This perfectly matches the context where "medicine" refers to the pharmaceutical drug being discussed.

3. sense_key=medicine%1:04:00:: - "the learned profession that is mastered by graduate training in a medical school..." - This refers to the medical profession or practice, not a drug.

4. sense_key=medicine%1:04:02:: - "punishment for one's actions" - This is clearly not applicable.

The context is clearly about a pharmaceutical drug (Alimta), and the sentence "The medicine can only be obtained with a prescription" is referring to this drug. This is sense 2, which defines medicine as "something that treats or prevents or alleviates the symptoms of disease" with synonyms like "medication" and "medicinal drug."

The answer should be sense index 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can <t>only</t> be obtained with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

The word "only" in "The medicine can only be obtained with a prescription" means that a prescription is the exclusive or sole means of obtaining the medicine. No other method is available. This matches sense 2: "without any others being included or involved" with synonyms "exclusively, solely" - indicating that the prescription requirement is the single, exclusive way to obtain the medication.

reasoning_content:
Let me analyze the context where "only" appears:

"The medicine can only be obtained with a prescription."

This means that the medicine can be obtained in one way: with a prescription. There are no other ways to obtain it. It's not available without a prescription.

Let me look at the candidate senses:

1. "and nothing more" / "merely, simply, just, but" - This would mean "The medicine can merely be obtained..." or "The medicine can simply be obtained..." This doesn't quite fit the context.

2. "without any others being included or involved" / "entirely, exclusively, solely, alone" - This would mean the medicine is exclusively obtained with a prescription, or solely obtained with a prescription. This fits well - it means there's no other way to obtain it.

3. "with nevertheless the final result" - This doesn't fit. It's used for phrases like "He arrived only to find..."

4. "in the final outcome" - This doesn't fit the context well.

5. "except that" - This doesn't fit.

6. "never except when" / "only if, only when" - This would be more like "call me only if..." but the sentence structure doesn't match this usage.

7. "as recently as" - This doesn't fit at all.

The best match is sense 2: "without any others being included or involved" with synonyms "entirely, exclusively, solely, alone". The sentence means the medicine can be obtained exclusively/solely with a prescription - there's no other way to obtain it. This is the sense of restriction or limitation to one option.

Actually, let me reconsider. Sense 1 "and nothing more" with synonyms "merely, simply, just" could also work. The sentence could mean "The medicine can be obtained with nothing more than a prescription" or "The medicine can merely be obtained with a prescription."

But sense 2 with "exclusively, solely" seems more precise - it emphasizes that a prescription is the only means, not just that nothing more is needed. It conveys the restriction more clearly.
Sense 2 captures the intended meaning best. The exclusive nature of requiring a prescription—that there's no alternative method—aligns with how "solely" and "exclusively" function in this context.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: obtain
Target surface form: obtained
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be <t>obtained</t> with a prescription. How is Alimta used?

Candidate senses:
1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation; His movie received a good review
3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context describes how to acquire or come into possession of the medicine: "The medicine can only be obtained with a prescription." This directly matches sense 1 (come into possession of). Sense 2 involves abstract treatment/reception, and sense 3 concerns validity or applicability—neither of which fit this concrete, practical description of acquiring medication through a prescription.

reasoning_content:
Let me analyze the context and the candidate senses for the word "obtained".

The sentence is: "The medicine can only be obtained with a prescription."

Let me examine each sense:

1. sense_key=obtain%2:40:00:: | definition=come into possession of | examples=How did you obtain the visa?
   - This sense means acquiring or getting something into one's possession
   - "The medicine can only be obtained with a prescription" means you can only come into possession of the medicine by getting a prescription
   - This fits very well

2. sense_key=obtain%2:30:00:: | definition=receive a specified treatment (abstract) | synonyms=receive, get, find, incur | examples=These aspects of civilization do not find expression or receive an interpretation
   - This is about receiving abstract treatment or interpretation
   - The examples talk about abstract concepts receiving treatment
   - This doesn't fit as well in the concrete context of getting medicine

3. sense_key=obtain%2:42:00:: | definition=be valid, applicable, or true | synonyms=prevail, hold | examples=This theory still holds
   - This is about something being valid or true
   - "The medicine can only be obtained..." doesn't mean "the medicine can only be valid"
   - This doesn't fit at all

The context is clearly about acquiring or getting medicine - you need a prescription to get/acquire it. This is the most concrete and direct sense of "obtain" meaning "come into possession of."

The answer should be sense index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: prescription
Target surface form: prescription
Context:
It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a <t>prescription</t>. How is Alimta used?

Candidate senses:
1. sense_key=prescription%1:10:00:: | definition=directions prescribed beforehand; the action of prescribing authoritative rules or directions | examples=I tried to follow her prescription for success
2. sense_key=prescription%1:06:00:: | definition=a drug that is available only with written instructions from a doctor or dentist to a pharmacist | synonyms=prescription drug, prescription medicine, ethical drug | examples=he told the doctor that he had been taking his prescription regularly
3. sense_key=prescription%1:10:02:: | definition=written instructions for an optician on the lenses for a given person
4. sense_key=prescription%1:10:01:: | definition=written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 4}
```

The context indicates that Alimta "can only be obtained with a prescription," referring to the written authorization and instructions from a physician concerning drug dosage and administration. This matches sense 4, which specifically defines prescription as "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient."

reasoning_content:
Let me analyze the context to determine which sense of "prescription" is being used.

The sentence is: "The medicine can only be obtained with a prescription."

This is clearly referring to a medicine/drug that requires a doctor's authorization to obtain. Let me look at each sense:

1. sense_key=prescription%1:10:00:: - "directions prescribed beforehand; the action of prescribing authoritative rules or directions" - This is too general and doesn't specifically relate to medicine.

2. sense_key=prescription%1:06:00:: - "a drug that is available only with written instructions from a doctor or dentist to a pharmacist" - This matches the context. The text is saying the medicine can only be obtained with a prescription, meaning it requires doctor's written instructions.

3. sense_key=prescription%1:10:02:: - "written instructions for an optician on the lenses for a given person" - This is specifically for eyeglasses/contact lenses, not applicable here.

4. sense_key=prescription%1:10:01:: - "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient" - This is also about medical prescriptions, written instructions for drugs.

Both senses 2 and 4 seem relevant. Let me think more carefully:

Sense 2 defines prescription as "a drug that is available only with written instructions from a doctor or dentist to a pharmacist" - This seems to define prescription as the drug itself that requires a prescription.

Sense 4 defines prescription as "written instructions from a physician or dentist to a druggist concerning the form and dosage of a drug to be issued to a given patient" - This defines prescription as the written instructions themselves.

In the context "The medicine can only be obtained with a prescription," the word "prescription" refers to the written authorization/instructions from a doctor needed to obtain the medicine. This better matches sense 4, which describes the written instructions from a physician.
The phrase "with a prescription" points to the document or authorization itself rather than describing the drug's status. Sense 4 captures this distinction—it's the actual written instructions from a physician that one needs to present, not simply a reference to a drug that happens to require authorization.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
What is Alimta used for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta <t>used</t>? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context is asking "How is Alimta used?" in a medical treatment scenario. The word "used" here means to employ or apply the drug for a particular purpose (treating cancer). This matches sense 1: "put into service; make work or employ for a particular purpose." The synonyms like "utilize," "apply," and "employ" all fit naturally in this medical context.

reasoning_content:
Let me analyze the context to determine which sense of "used" best fits.

The context is: "How is Alimta used?"

This is a medical document about Alimta, a cancer drug. The sentence is asking "How is Alimta used?" - in other words, how is this medicine applied/employed in medical treatment?

Let me examine each sense:

1. sense_key=use%2:34:01:: "put into service; make work or employ for a particular purpose" - This means to employ something for a specific purpose. The drug is being employed/applied for treating cancer. This seems very relevant.

2. sense_key=use%2:34:02:: "take or consume (regularly or habitually)" - This is about consuming substances like drugs regularly. While Alimta is taken, the question is asking HOW it's used (administered), not about consuming it habitually.

3. sense_key=use%2:34:00:: "use up, consume fully" - This is about consuming/expending something completely. Not the right sense.

4. sense_key=use%2:41:14:: "seek or achieve an end by using to one's advantage" - This is about manipulating something to one's advantage. Doesn't fit here.

5. sense_key=use%2:41:04:: "avail oneself to" - This means to make use of or employ something. Could fit, but less direct.

6. sense_key=use%2:41:03:: "habitually do something (use only in the past tense)" - This is for past habitual actions like "used to call". Doesn't fit the question "How is Alimta used?"

The best fit is sense 1: "put into service; make work or employ for a particular purpose." The medicine is being employed/put into service for the purpose of treating cancer. The synonyms "utilize, apply, employ" all work perfectly with this context - "How is Alimta utilized/applied/employed?"
Sense 1 is the correct answer.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: only
Target surface form: only
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should <t>only</t> be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=only%4:02:02:: | definition=and nothing more | synonyms=merely, simply, just, but | examples=I was merely asking; it is simply a matter of time
2. sense_key=only%4:02:01:: | definition=without any others being included or involved | synonyms=entirely, exclusively, solely, alone | examples=was entirely to blame; a school devoted entirely to the needs of problem children
3. sense_key=only%4:02:00:: | definition=with nevertheless the final result | examples=He arrived only to find his wife dead; We won only to lose again in the next round
4. sense_key=only%4:02:04:: | definition=in the final outcome | examples=These news will only make you more upset
5. sense_key=only%4:02:06:: | definition=except that | examples=It was the same story; only this time she came out better
6. sense_key=only%4:02:03:: | definition=never except when | synonyms=only if, only when | examples=call me only if your cold gets worse
7. sense_key=only%4:02:05:: | definition=as recently as | examples=I spoke to him only an hour ago

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

The word "only" in the sentence "Alimta should only be given under the supervision of a doctor..." means that the medicine should be administered EXCLUSIVELY or SOLELY under medical supervision. This matches sense 2, which has the definition "without any others being included or involved" with synonyms "entirely, exclusively, solely, alone." The context indicates that no other conditions or circumstances should apply—the only acceptable way to administer Alimta is under a qualified doctor's supervision.

reasoning_content:
Let me analyze the context and the target word "only" in the sentence:

"Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

The word "only" here means that Alimta should be given EXCLUSIVELY or SOLELY under the supervision of a qualified doctor. It indicates that no other condition should apply - the only way it should be given is under this supervision.

Let me examine the candidate senses:

1. sense 1: "and nothing more" - synonyms: merely, simply, just, but. This means "to a limited extent" or "that is all"
   Example: "I was merely asking"

2. sense 2: "without any others being included or involved" - synonyms: entirely, exclusively, solely, alone
   Examples: "was entirely to blame; a school devoted entirely to the needs of problem children"

3. sense 3: "with nevertheless the final result" - This is about a contrasting or ironic result
   Example: "He arrived only to find his wife dead"

4. sense 4: "in the final outcome" - Examples: "These news will only make you more upset"

5. sense 5: "except that" - Example: "It was the same story; only this time she came out better"

6. sense 6: "never except when" - This means "if and only if"
   Example: "call me only if your cold gets worse"

7. sense 7: "as recently as" - This is about time
   Example: "I spoke to him only an hour ago"

In the context: "Alimta should only be given under the supervision of a doctor..."

This means the medicine should be given EXCLUSIVELY or SOLELY under the supervision of a doctor. This is the meaning of sense 2 - "without any others being included or involved" with synonyms "entirely, exclusively, solely, alone".

The answer should be sense 2.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: give
Target surface form: given
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be <t>given</t> under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=give%2:40:03:: | definition=cause to have, in the abstract sense or physical sense | examples=She gave him a black eye; The draft gave me a cold
2. sense_key=give%2:40:05:: | definition=be the cause or source of | synonyms=yield, afford | examples=He gave me a lot of trouble; Our meeting afforded much interesting information
3. sense_key=give%2:40:00:: | definition=transfer possession of something concrete or abstract to somebody | examples=I gave her my money; can you give me lessons?
4. sense_key=give%2:40:07:: | definition=convey or reveal information | examples=Give one's name
5. sense_key=give%2:32:01:: | definition=convey, as of a compliment, regards, attention, etc.; bestow | synonyms=pay | examples=Don't pay him any mind; give the orders
6. sense_key=give%2:36:02:: | definition=organize or be responsible for | synonyms=hold, throw, have, make | examples=hold a reception; have, throw, or make a party
7. sense_key=give%2:32:00:: | definition=convey or communicate; of a smile, a look, a physical gesture | synonyms=throw | examples=Throw a glance; She gave me a dirty look
8. sense_key=give%2:40:01:: | definition=give as a present; make a gift of | synonyms=gift, present | examples=What will you give her for her birthday?
9. sense_key=give%2:36:03:: | definition=cause to happen or be responsible for | synonyms=yield | examples=His two singles gave the team the victory
10. sense_key=give%2:31:02:: | definition=dedicate | synonyms=pay, devote | examples=give thought to; give priority to
11. sense_key=give%2:36:00:: | definition=give or supply | synonyms=render, yield, return, generate | examples=The cow brings in 5 liters of milk; This year's crop yielded 1,000 bushels of corn
12. sense_key=give%2:40:09:: | definition=transmit (knowledge or skills) | synonyms=impart, leave, pass on | examples=give a secret to the Russians; leave your name and address here
13. sense_key=give%2:36:01:: | definition=bring about | synonyms=establish | examples=The trompe l'oeil-illusion establishes depth
14. sense_key=give%2:40:02:: | definition=leave with; give temporarily | examples=Can I give you my keys while I go in the pool?; Can I give you the children for the weekend?
15. sense_key=give%2:41:00:: | definition=emit or utter | examples=Give a gulp; give a yelp
16. sense_key=give%2:40:10:: | definition=endure the loss of | synonyms=sacrifice | examples=He gave his life for his children; I gave two sons to the war
17. sense_key=give%2:40:06:: | definition=place into the hands or custody of | synonyms=pass, hand, reach, pass on, turn over | examples=hand me the spoon, please; Turn the files over to me, please
18. sense_key=give%2:32:03:: | definition=give entirely to a specific person, activity, or cause | synonyms=dedicate, consecrate, commit, devote | examples=She committed herself to the work of God; give one's talents to a good cause
19. sense_key=give%2:40:13:: | definition=give (as medicine) | examples=I gave him the drug
20. sense_key=give%2:40:14:: | definition=give or convey physically | synonyms=apply | examples=She gave him First Aid; I gave him a punch in the nose
21. sense_key=give%2:32:02:: | definition=bestow | synonyms=render | examples=give homage; render thanks
22. sense_key=give%2:40:11:: | definition=bestow, especially officially | synonyms=grant | examples=grant a degree; give a divorce
23. sense_key=give%2:38:00:: | definition=move in order to make room for someone for something | synonyms=move over, give way, ease up, yield | examples=The park gave way to a supermarket; `Move over,' he told the crowd
24. sense_key=give%2:34:00:: | definition=give food to | synonyms=feed | examples=Feed the starving children in India; don't give the child this tough meat
25. sense_key=give%2:40:08:: | definition=contribute to some cause | synonyms=contribute, chip in, kick in | examples=I gave at the office
26. sense_key=give%2:38:13:: | definition=break down, literally or metaphorically | synonyms=collapse, fall in, cave in, give way, break, founder | examples=The wall collapsed; The business collapsed
27. sense_key=give%2:31:00:: | definition=estimate the duration or outcome of something | examples=He gave the patient three months to live; I gave him a very good chance at success
28. sense_key=give%2:41:10:: | definition=execute and deliver | examples=Give bond
29. sense_key=give%2:40:12:: | definition=deliver in exchange or recompense | examples=I'll give you three books for four CDs
30. sense_key=give%2:40:15:: | definition=afford access to | synonyms=afford, open | examples=the door opens to the patio; The French doors give onto a terrace
31. sense_key=give%2:36:13:: | definition=present to view | examples=He gave the sign to start
32. sense_key=give%2:36:12:: | definition=perform for an audience | examples=Pollini is giving another concert in New York
33. sense_key=give%2:35:00:: | definition=be flexible under stress of physical force | synonyms=yield | examples=This material doesn't give
34. sense_key=give%2:34:10:: | definition=propose | examples=He gave the first of many toasts at the birthday party
35. sense_key=give%2:32:11:: | definition=accord by verdict | examples=give a decision for the plaintiff
36. sense_key=give%2:32:08:: | definition=manifest or show | examples=This student gives promise of real creativity; The office gave evidence of tampering
37. sense_key=give%2:32:15:: | definition=offer in good faith | examples=He gave her his word
38. sense_key=give%2:32:14:: | definition=submit for consideration, judgment, or use | examples=give one's opinion; give an excuse
39. sense_key=give%2:32:09:: | definition=guide or direct, as by behavior of persuasion | examples=You gave me to think that you agreed with me
40. sense_key=give%2:32:07:: | definition=allow to have or take | examples=I give you two minutes to respond
41. sense_key=give%2:32:10:: | definition=inflict as a punishment | examples=She gave the boy a good spanking; The judge gave me 10 years
42. sense_key=give%2:30:13:: | definition=occur | examples=what gives?
43. sense_key=give%2:29:11:: | definition=consent to engage in sexual intercourse with a man | examples=She gave herself to many men
44. sense_key=give%2:29:10:: | definition=proffer (a body part) | examples=She gave her hand to her little sister

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 19}
```

The context describes administering Alimta (a medicine) under medical supervision. Sense 19 explicitly defines "give (as medicine)" with the example "I gave him the drug," which perfectly matches the scenario of a medical professional administering a pharmaceutical treatment to a patient.

reasoning_content:
Let me analyze the context of "given" in this sentence:

"Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

In this context, "given" refers to administering a medicine/drug. It's about providing or administering Alimta to a patient.

Looking at the candidate senses, I need to find which one best describes administering medicine:

Sense 19: "give (as medicine)" - "I gave him the drug" - This is the most specific and direct match! It explicitly states it's about giving as medicine.

Other related senses:
- Sense 3: "transfer possession of something concrete or abstract to somebody" - This is more general
- Sense 14: "leave with; give temporarily" - Not quite right
- Sense 17: "place into the hands or custody of" - Could work but not as specific

Sense 19 is clearly the best match because it's specifically about administering medicine, which is exactly what the context describes - giving Alimta (a medicine) to patients.

The answer should be sense_index: 19


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: doctor
Target surface form: doctor
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a <t>doctor</t> who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context makes clear that "doctor" refers to a licensed medical practitioner who is qualified in administering anticancer chemotherapy. This matches sense 1 (a licensed medical practitioner), which is the standard usage in medical contexts. The other senses are not applicable: sense 2 refers to Catholic Church saints, sense 3 refers to children's pretend play, and sense 4 refers to academic doctorate holders.

reasoning_content:
Let me analyze the context for the word "doctor" in this sentence:

"Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

The context is about a cancer treatment medication (Alimta) being administered. The sentence states that it should be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. This clearly refers to a medical professional who administers cancer treatment.

Looking at the candidate senses:

1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
   - This is a licensed medical practitioner. This fits the context perfectly - someone who is qualified and can supervise medical treatment.

2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching
   - This is about saints in the Roman Catholic Church. This doesn't fit the context at all.

3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office
   - This is about children's play/game. This doesn't fit the medical context.

4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution
   - This is about someone with a Ph.D. degree. While some medical doctors have PhDs, the context is specifically about someone who administers cancer chemotherapy, which refers to a medical practitioner, not necessarily someone with a Ph.D.

The best fit is sense 1, which describes a "licensed medical practitioner" - this is exactly what is meant in the context of administering cancer medication under medical supervision.
The answer is {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: use
Context:
Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the <t>use</t> of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight).

Candidate senses:
1. sense_key=use%1:04:00:: | definition=the act of using | synonyms=usage, utilization, utilisation, employment, exercise | examples=he warned against the use of narcotic drugs; skilled in the utilization of computers
2. sense_key=use%1:07:00:: | definition=what something is used for | synonyms=function, purpose, role | examples=the function of an auger is to bore holes; ballet is beautiful but what use is it?
3. sense_key=use%1:07:02:: | definition=a particular service | examples=he put his knowledge to good use; patrons have their uses
4. sense_key=use%1:22:00:: | definition=(economics) the utilization of economic goods to satisfy needs or in manufacturing | synonyms=consumption, economic consumption, usance, use of goods and services | examples=the consumption of energy has increased steadily
5. sense_key=use%1:04:01:: | definition=(psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition | synonyms=habit | examples=owls have nocturnal habits; she had a habit twirling the ends of her hair
6. sense_key=use%1:04:02:: | definition=exerting shrewd or devious influence especially for one's own advantage | synonyms=manipulation | examples=his manipulation of his friends was scandalous
7. sense_key=use%1:07:03:: | definition=(law) the exercise of the legal right to enjoy the benefits of owning property | synonyms=enjoyment | examples=we were given the use of his boat

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The target phrase "qualified in the use of anticancer chemotherapy" refers to expertise in the **act of applying or employing** anticancer chemotherapy. This matches sense 1 ("the act of using"), which has synonyms like "usage," "utilization," and "employment." The context is about the application/administration of the treatment, not its purpose (sense 2), a particular service (sense 3), or any other sense.

reasoning_content:
Let me analyze the context to determine the best sense for "use" in the phrase "qualified in the use of anticancer chemotherapy."

The sentence is: "Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy."

Here, "use" refers to how something is applied or employed - specifically, it's about the application or employment of anticancer chemotherapy. The doctor needs to be qualified in the application/employment of this treatment.

Let me review the candidate senses:

1. use%1:04:00:: - "the act of using" with synonyms usage, utilization, employment, exercise. This refers to the act of applying or employing something.

2. use%1:07:00:: - "what something is used for" - the function or purpose. Not about the act itself.

3. use%1:07:02:: - "a particular service" - not fitting here.

4. use%1:22:00:: - economic/consumption sense - not applicable.

5. use%1:04:01:: - psychology/habit sense - not applicable.

6. use%1:04:02:: - manipulation sense - not applicable.

7. use%1:07:03:: - legal right sense - not applicable.

The context clearly points to sense 1, which is "the act of using" or "utilization/employment." The phrase "qualified in the use of anticancer chemotherapy" means qualified in the application/employment/utilization of this treatment. This matches the definition and examples given for sense 1.

Sense 1 is the best fit. The answer should be {"sense_index": 1}.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: dose
Target surface form: dose
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended <t>dose</t> of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
Looking at the context, the sentence is: "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes."

This is clearly discussing a measured quantity of medicine (Alimta) that is to be taken/administered to a patient. The dose is specified as 500 mg per square metre of body surface area.

Let me analyze the candidate senses:

1. sense_key=dose%1:06:00:: | definition=a measured portion of medicine taken at any one time | synonyms=dosage
   - This refers to a measured portion of medicine taken at any one time. The context is about the recommended dose of Alimta, which is a medicine.

2. sense_key=dose%1:23:00:: | definition=the quantity of an active agent (substance or radiation) taken in or absorbed at any one time | synonyms=dosage
   - This is similar but broader, referring to any active agent including radiation.

3. sense_key=dose%1:26:00:: | definition=a communicable infection transmitted by sexual intercourse or genital contact | synonyms=venereal disease, VD, venereal infection, social disease, Cupid's itch, Cupid's disease
   - This is clearly not relevant. This is referring to a sexually transmitted disease.

4. sense_key=dose%1:06:01:: | definition=street name for lysergic acid diethylamide | synonyms=acid, back breaker, battery-acid, dot, Elvis, loony toons
   - This is slang for LSD, not relevant to the medical context.

Both senses 1 and 2 are relevant. Sense 1 is specifically about medicine, while sense 2 is more general (active agent could be medicine, radiation, etc.). In this context, since we're talking about a measured portion of medicine (Alimta), sense 1 seems most appropriate.
The correct answer is sense 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: mg
Target surface form: mg
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 <t>mg</t> per square metre of body surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=mg%1:23:00:: | definition=one thousandth (1/1,000) gram | synonyms=milligram
2. sense_key=mg%1:27:00:: | definition=a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) | synonyms=magnesium, atomic number 12

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context clearly indicates a pharmaceutical dosage measurement: "The recommended dose of Alimta is 500 mg per square metre of body surface area." This refers to milligrams as a unit of mass measurement, not to magnesium the chemical element. In medical contexts, drug doses are always expressed in mass units like milligrams.

reasoning_content:
Let me analyze the context for the word "mg" (milligrams or magnesium).

From the context: "The recommended dose of Alimta is 500 mg per square metre of body surface area"

This is clearly referring to a measurement of medicine dosage. The number "500 mg" in the context of a pharmaceutical dose indicates a mass measurement, not a chemical element.

Let me look at the two candidate senses:

1. sense_key=mg%1:23:00:: | definition=one thousandth (1/1,000) gram | synonyms=milligram
   - This is the unit of measurement (milligram)

2. sense_key=mg%1:27:00:: | definition=a light silver-white ductile bivalent metallic element... | synonyms=magnesium, atomic number 12
   - This is the chemical element magnesium

In the context of "500 mg per square metre of body surface area" in a medical/pharmaceutical setting, this is definitely referring to milligrams as a unit of measurement, not the element magnesium. A dose would never be expressed as "500 magnesium atoms per square metre" - that doesn't make sense medically.

The answer should be sense 1 (milligram/one thousandth gram).


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: body
Target surface form: body
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of <t>body</t> surface area (calculated using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire
2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity | examples=the whole body filed out of the auditorium; the student body
3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person | synonyms=dead body | examples=they found the body in the lake
4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects | examples=heavenly body
5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs | synonyms=torso, trunk | examples=they moved their arms and legs and bodies
6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system | examples=a body of law; a body of doctrine
7. sense_key=body%1:07:00:: | definition=the property of holding together and retaining its shape | synonyms=consistency, consistence, eubstance | examples=wool has more body than rayon; when the dough has enough consistency it is ready to bake
8. sense_key=body%1:10:00:: | definition=the central message of a communication | examples=the body of the message was short
9. sense_key=body%1:07:01:: | definition=the main mass of a thing
10. sense_key=body%1:06:01:: | definition=a resonating chamber in a musical instrument (as the body of a violin) | synonyms=soundbox
11. sense_key=body%1:06:00:: | definition=the external structure of a vehicle | examples=the body of the car was badly rusted

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context "body surface area" refers to the entire physical structure of the human organism, which is used to calculate the medication dosage. This matches sense 1 (the entire structure of an organism), not sense 5 (which refers only to torso/trunk excluding head and limbs), nor any other sense.

reasoning_content:
Let me analyze the context of "body" in this medical text.

The sentence is: "The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient's height and weight)."

This is referring to "body surface area" which is a medical term. The body here is referring to the physical human organism - the entire structure of the body. However, looking more carefully at the meaning:

1. sense_key=body%1:08:00:: | definition=the entire structure of an organism (an animal, plant, or human being) | synonyms=organic structure, physical structure | examples=he felt as if his whole body were on fire

This is referring to the entire organism/structure. "Body surface area" is a measure that encompasses the entire external surface of the human body, so this refers to the whole physical structure of the organism.

2. sense_key=body%1:14:00:: | definition=a group of persons associated by some common tie or occupation and regarded as an entity - NOT relevant

3. sense_key=body%1:08:02:: | definition=a natural object consisting of a dead animal or person - NOT relevant

4. sense_key=body%1:17:00:: | definition=an individual 3-dimensional object that has mass and that is distinguishable from other objects - Could fit, but too general

5. sense_key=body%1:08:01:: | definition=the body excluding the head and neck and limbs - This is torso/trunk, NOT the whole body

6. sense_key=body%1:14:02:: | definition=a collection of particulars considered as a system - NOT relevant

The correct answer is sense 1 - "the entire structure of an organism" because "body surface area" refers to the total external surface area of the entire human organism.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: calculate
Target surface form: calculated
Context:
Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells. Alimta is used in combination with cisplatin in patients who have not been treated before, and on its own in patients who have received another type of chemotherapy in the past. The medicine can only be obtained with a prescription. How is Alimta used? Alimta should only be given under the supervision of a doctor who is qualified in the use of anticancer chemotherapy. The recommended dose of Alimta is 500 mg per square metre of body surface area (<t>calculated</t> using the patient s height and weight). It is given once every three weeks as an intravenous infusion lasting 10 minutes.

Candidate senses:
1. sense_key=calculate%2:31:00:: | definition=make a mathematical calculation or computation | synonyms=cipher, cypher, compute, work out, reckon, figure
2. sense_key=calculate%2:31:03:: | definition=judge to be probable | synonyms=estimate, reckon, count on, figure, forecast
3. sense_key=calculate%2:40:00:: | definition=keep an account of | synonyms=account
4. sense_key=calculate%2:32:01:: | definition=predict in advance | synonyms=forecast
5. sense_key=calculate%2:31:02:: | definition=specifically design a product, event, or activity for a certain public | synonyms=aim, direct
6. sense_key=calculate%2:31:05:: | definition=have faith or confidence in | synonyms=count, bet, depend, look, reckon | examples=you can count on me to help you any time; Look to your friends for support

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

reasoning_content:
Let me analyze the context where "calculated" is used:

"The recommended dose of Alimta is 500 mg per square metre of body surface area (calculated using the patient's height and weight)."

Here, "calculated" is used in the sense of performing a mathematical computation or determination based on the patient's height and weight to determine the body surface area. This is clearly referring to a mathematical calculation.

Looking at the candidate senses:
1. "make a mathematical calculation or computation" - synonyms include cipher, cypher, compute, work out, reckon, figure. This fits perfectly.
2. "judge to be probable" - This is about estimation or probability judgment, not fitting here.
3. "keep an account of" - This is about accounting, not applicable.
4. "predict in advance" - This is about forecasting, not applicable.
5. "specifically design a product, event, or activity for a certain public" - This is about design/targeting, not applicable.
6. "have faith or confidence in" - This is about trust/confidence, not applicable.

The context clearly shows that "calculated" means to perform a mathematical calculation or computation based on height and weight. This is sense 1.

The answer should be {"sense_index": 1}