[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: doctor
Target surface form: doctor
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your <t>doctor</t> or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR).

Candidate senses:
1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context clearly refers to a licensed medical practitioner who can provide information about medical conditions and treatment. This matches sense 1 (a licensed medical practitioner/physician) perfectly, as evidenced by the medical context of the EPAR document and the mention of contacting the doctor regarding "your medical condition or your treatment."

reasoning_content:
The target word is "doctor" in the context of a medical document. Let me analyze the context:

"If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist."

This is clearly referring to a medical professional who can provide information about medical conditions and treatment. The context is medical in nature.

Let me examine the candidate senses:

1. sense_key=doctor%1:18:00:: | definition=a licensed medical practitioner | synonyms=doc, physician, MD, Dr., medico | examples=I felt so bad I went to see my doctor
   - This fits perfectly. It's about a medical practitioner in a medical context.

2. sense_key=doctor%1:18:02:: | definition=(Roman Catholic Church) a title conferred on 33 saints who distinguished themselves through the orthodoxy of their theological teaching | synonyms=Doctor of the Church | examples=the Doctors of the Church greatly influenced Christian thought down to the late Middle Ages
   - This is clearly not relevant to the context.

3. sense_key=doctor%1:04:00:: | definition=children take the roles of physician or patient or nurse and pretend they are at the physician's office | examples=the children explored each other's bodies by playing the game of doctor
   - This is about children playing, not relevant here.

4. sense_key=doctor%1:18:01:: | definition=a person who holds Ph.D. degree (or the equivalent) from an academic institution | synonyms=Dr. | examples=she is a doctor of philosophy in physics
   - This is about academic degree holders, not medical practitioners.

The best match is sense 1, which is about a licensed medical practitioner. The context clearly indicates a medical professional being contacted for medical condition information.


attempt_kind: initial

status: success

[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: want
Target surface form: want
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you <t>want</t> more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=want%2:37:00:: | definition=feel or have a desire for; want strongly | synonyms=desire | examples=I want to go home now; I want my own room
2. sense_key=want%2:34:00:: | definition=have need of | synonyms=need, require | examples=This piano wants the attention of a competent tuner
3. sense_key=want%2:35:00:: | definition=hunt or look for; want for a particular reason | examples=Your former neighbor is wanted by the FBI; Uncle Sam wants you
4. sense_key=want%2:31:01:: | definition=wish or demand the presence of | examples=I want you here at noon!
5. sense_key=want%2:42:01:: | definition=be without, lack; be deficient in | examples=want courtesy; want the strength to go on living

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

finish_reason: stop

role: assistant

reasoning_content:
Let me analyze the context to find the best sense for "want" in the sentence:

"If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

Looking at the candidate senses:

1. sense_key=want%2:37:00:: | definition=feel or have a desire for; want strongly | synonyms=desire | examples=I want to go home now; I want my own room

2. sense_key=want%2:34:00:: | definition=have need of | synonyms=need, require | examples=This piano wants the attention of a competent tuner

3. sense_key=want%2:35:00:: | definition=hunt or look for; want for a particular reason | examples=Your former neighbor is wanted by the FBI; Uncle Sam wants you

4. sense_key=want%2:31:01:: | definition=wish or demand the presence of | examples=I want you here at noon!

5. sense_key=want%2:42:01:: | definition=be without, lack; be deficient in | examples=want courtesy; want the strength to go on living

In the context: "If you want more information..."

This is expressing a desire or wish for information. The person is saying they desire/wish for more information. This matches sense 1 very well: "feel or have a desire for; want strongly" with examples like "I want to go home now."

Sense 2 (have need of) could potentially work, but the examples show a more formal/archaic usage ("This piano wants the attention...").

Sense 3 is about being sought by law enforcement, which doesn't fit.

Sense 4 is about demanding someone's presence, which doesn't fit.

Sense 5 is about lacking something, which doesn't fit.

The best match is sense 1: feel or have a desire for; want strongly.

type: thinking

currency: USD


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: more
Target surface form: more
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want <t>more</t> information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=more%3:00:01:: | definition=(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree | synonyms=more than | examples=more land; more support
2. sense_key=more%3:00:02:: | definition=(comparative of `many' used with count nouns) quantifier meaning greater in number | examples=a hall with more seats; we have no more bananas

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The target word "more" modifies "information," which is a mass noun (uncountable). Sense 1 correctly applies to mass nouns with the comparative form of "much," similar to the provided example "more support." Sense 2 applies to count nouns (using "many" as the base), which is not appropriate here.

reasoning_content:
Let me analyze the context and the two candidate senses for "more".

The sentence in question is: "If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

Let me look at the two senses:

1. Sense 1: "(comparative of `much' used with mass nouns) a quantifier meaning greater in size or amount or extent or degree"
   - Examples: "more land; more support"
   - This is used with mass nouns (uncountable nouns)

2. Sense 2: "(comparative of `many' used with count nouns) quantifier meaning greater in number"
   - Examples: "a hall with more seats; we have no more bananas"
   - This is used with count nouns (countable nouns)

In the target sentence, "more" modifies "information". The word "information" is a mass noun (uncountable) - we don't say "informations" in English. This is similar to the example "more support" which is a mass noun modified by "more".

Therefore, the correct sense should be sense 1, which deals with mass nouns and uses "much" as the base comparative.

The answer should be {"sense_index": 1}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: information
Target surface form: information
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more <t>information</t> on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=information%1:10:00:: | definition=a message received and understood | synonyms=info
2. sense_key=information%1:09:00:: | definition=knowledge acquired through study or experience or instruction
3. sense_key=information%1:10:02:: | definition=formal accusation of a crime
4. sense_key=information%1:14:00:: | definition=a collection of facts from which conclusions may be drawn | synonyms=data | examples=statistical data
5. sense_key=information%1:07:00:: | definition=(communication theory) a numerical measure of the uncertainty of an outcome | synonyms=selective information, entropy | examples=the signal contained thousands of bits of information

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

content:
```json
{"sense_index": 1}
```

reasoning_content:
Let me analyze the context to determine the best sense for "information" in this sentence:

"If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

The context is about a medical document explaining how to get more details about the basis of medical recommendations.

Let me examine each sense:

1. sense_key=information%1:10:00:: | definition=a message received and understood | synonyms=info
   - This is about a message/communication

2. sense_key=information%1:09:00:: | definition=knowledge acquired through study or experience or instruction
   - This is about knowledge acquired through various means

3. sense_key=information%1:10:02:: | definition=formal accusation of a crime
   - Not relevant; this is legal terminology unrelated to the context

4. sense_key=information%1:14:00:: | definition=a collection of facts from which conclusions may be drawn | synonyms=data | examples=statistical data
   - This is about facts/data that can be used to draw conclusions

5. sense_key=information%1:07:00:: | definition=(communication theory) a numerical measure of the uncertainty of an outcome | synonyms=selective information, entropy
   - This is a technical term from information theory, unlikely in this context

In this medical context, the person wants "more information on the basis of the CHMP recommendations" - they want to understand or learn details about the scientific basis of the recommendations.

Sense 1 (a message received and understood) fits well - they want to receive and understand a message about the basis of the recommendations.

Sense 2 (knowledge acquired through study) also fits - they want to acquire knowledge.

Sense 4 (a collection of facts) could fit - they want facts about the recommendations.

However, sense 1 seems most appropriate here.

The person is essentially requesting details and facts about the recommendations be communicated to them. Sense 1 captures this most directly—it's the most common and straightforward usage of "information" when referring to facts or details someone wants to learn about. This is the best fit.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: basis
Target surface form: basis
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the <t>basis</t> of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=basis%1:24:00:: | definition=a relation that provides the foundation for something | synonyms=footing, ground | examples=they were on a friendly footing; he worked on an interim basis
2. sense_key=basis%1:09:00:: | definition=the fundamental assumptions from which something is begun or developed or calculated or explained | synonyms=base, foundation, fundament, groundwork, cornerstone | examples=the whole argument rested on a basis of conjecture
3. sense_key=basis%1:24:01:: | definition=the most important or necessary part of something | synonyms=base | examples=the basis of this drink is orange juice

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 2}
```

The context asks for information about "the basis of the CHMP recommendations," referring to the fundamental reasoning and assumptions underlying those recommendations. This matches sense 2, which defines basis as "the fundamental assumptions from which something is begun or developed or calculated or explained." The example "the whole argument rested on a basis of conjecture" parallels the structure perfectly—both refer to the foundational reasoning behind a conclusion or recommendation.

reasoning_content:
Let me analyze the context for the word "basis" in this sentence:

"If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

The sentence is asking for information about the foundation or reasoning behind the CHMP recommendations. Let me examine each sense:

1. Sense 1 (basis%1:24:00::): "a relation that provides the foundation for something" | synonyms: footing, ground | examples: "they were on a friendly footing; he worked on an interim basis"
   - This sense emphasizes a relation or situation foundation

2. Sense 2 (basis%1:09:00::): "the fundamental assumptions from which something is begun or developed or calculated or explained" | synonyms: base, foundation, fundament, groundwork, cornerstone | examples: "the whole argument rested on a basis of conjecture"
   - This sense is about fundamental assumptions and reasoning underlying something

3. Sense 3 (basis%1:24:01::): "the most important or necessary part of something" | synonyms: base | examples: "the basis of this drink is orange juice"
   - This sense is about the main component

In the context: "If you want more information on the basis of the CHMP recommendations" - this is asking about the fundamental reasoning, assumptions, or foundation for the recommendations.

This best matches Sense 2, which defines basis as "the fundamental assumptions from which something is begun or developed or calculated or explained." The example "the whole argument rested on a basis of conjecture" is very similar in structure.

The sentence is essentially asking for the underlying reasoning/foundation of the recommendations, which is exactly what sense 2 describes.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: recommendation
Target surface form: recommendations
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP <t>recommendations</t>, read the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=recommendation%1:10:00:: | definition=something (as a course of action) that is recommended as advisable
2. sense_key=recommendation%1:10:02:: | definition=something that recommends (or expresses commendation of) a person or thing as worthy or desirable | synonyms=testimonial, good word
3. sense_key=recommendation%1:07:00:: | definition=any quality or characteristic that gains a person a favorable reception or acceptance or admission | synonyms=passport | examples=her pleasant personality is already a recommendation; his wealth was not a passport into the exclusive circles of society

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context clearly indicates that "recommendations" refers to advice or guidance on a course of action provided by the CHMP regarding how to use the medicine. This directly matches sense 1, which defines recommendation as "something (as a course of action) that is recommended as advisable." The other senses refer to endorsements of persons/things or qualities that aid acceptance, neither of which applies here.

reasoning_content:
Let me analyze the context and the three candidate senses for the word "recommendations".

Context: "It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine."

Also: "If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

The word "recommendations" here refers to advice or guidance that is given as the result of an assessment. The CHMP is making recommendations on how to use the medicine - this is a course of action that is being advised.

Let me examine each sense:

1. sense_key=recommendation%1:10:00:: | definition=something (as a course of action) that is recommended as advisable
   - This fits perfectly. The CHMP is recommending a course of action (how to use the medicine) as advisable.

2. sense_key=recommendation%1:10:02:: | definition=something that recommends (or expresses commendation of) a person or thing as worthy or desirable | synonyms=testimonial, good word
   - This would be more like a testimonial or endorsement of a person/thing. This doesn't fit the context.

3. sense_key=recommendation%1:07:00:: | definition=any quality or characteristic that gains a person a favorable reception or acceptance or admission
   - This is about a quality or characteristic that helps someone get accepted. This doesn't fit the context.

Sense 1 is clearly the best fit. The CHMP is providing recommendations (advice on courses of action) for how to use the medicine.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: read
Target surface form: read
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, <t>read</t> the Scientific Discussion (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=read%2:31:00:: | definition=interpret something that is written or printed | examples=read the advertisement; Have you read Salman Rushdie?
2. sense_key=read%2:42:00:: | definition=have or contain a certain wording or form | synonyms=say | examples=The passage reads as follows; What does the law say?
3. sense_key=read%2:31:01:: | definition=look at, interpret, and say out loud something that is written or printed | examples=The King will read the proclamation at noon
4. sense_key=read%2:31:06:: | definition=obtain data from magnetic tapes | synonyms=scan | examples=This dictionary can be read by the computer
5. sense_key=read%2:31:02:: | definition=interpret the significance of, as of palms, tea leaves, intestines, the sky; also of human behavior | examples=She read the sky and predicted rain; I can't read his strange behavior
6. sense_key=read%2:31:09:: | definition=interpret something in a certain way; convey a particular meaning or impression | synonyms=take | examples=I read this address as a satire; How should I take this message?
7. sense_key=read%2:31:05:: | definition=be a student of a certain subject | synonyms=learn, study, take | examples=She is reading for the bar exam
8. sense_key=read%2:32:02:: | definition=indicate a certain reading; of gauges and instruments | synonyms=register, show, record | examples=The thermometer showed thirteen degrees below zero; The gauge read `empty'
9. sense_key=read%2:36:05:: | definition=audition for a stage role by reading parts of a role | examples=He is auditioning for `Julius Caesar' at Stratford this year
10. sense_key=read%2:31:08:: | definition=to hear and understand | examples=I read you loud and clear!
11. sense_key=read%2:31:04:: | definition=make sense of a language | synonyms=understand, interpret, translate | examples=She understands French; Can you read Greek?

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context is an instruction to read (examine and interpret) a written document - "the Scientific Discussion." This matches sense 1, which describes the basic action of interpreting something that is written or printed. The example "read the advertisement" is parallel to reading the Scientific Discussion document in this medical/informational context.

reasoning_content:
Let me analyze the context to find the best sense for "read" in this sentence:

"If you want more information on the basis of the CHMP recommendations, <t>read</t> the Scientific Discussion (also part of the EPAR)."

The sentence is an instruction or recommendation telling the reader to "read the Scientific Discussion." The user is being directed to read (as in examine/look at and interpret) a written document.

Let me evaluate each sense:

1. sense_key=read%2:31:00:: | "interpret something that is written or printed" | examples: "read the advertisement; Have you read Salman Rushdie?" - This fits well. It's about interpreting written text.

2. sense_key=read%2:42:00:: | "have or contain a certain wording or form" | example: "The passage reads as follows" - This doesn't fit. This is about what something says, not the action of reading.

3. sense_key=read%2:31:01:: | "look at, interpret, and say out loud something that is written or printed" | example: "The King will read the proclamation at noon" - This involves reading aloud, which isn't necessarily the case here.

4. sense_key=read%2:31:06:: | "obtain data from magnetic tapes" | This doesn't apply.

5. sense_key=read%2:31:02:: | "interpret the significance of, as of palms, tea leaves, intestines, the sky; also of human behavior" | This is too specific and doesn't apply.

6. sense_key=read%2:31:06:: | "interpret something in a certain way; convey a particular meaning or impression" - Could work but seems more interpretive than just reading.

7. sense_key=read%2:31:05:: | "be a student of a certain subject" | Doesn't fit.
The remaining senses—indicating gauge readings, auditioning for roles, hearing and understanding, and deciphering language—all fail to match the straightforward instruction to examine a document. Sense 1 clearly aligns best, as it directly parallels the example "read the advertisement" and captures the core meaning of consulting written material.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: discussion
Target surface form: Discussion
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific <t>Discussion</t> (also part of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=discussion%1:10:02:: | definition=an extended communication (often interactive) dealing with some particular topic | synonyms=treatment, discourse | examples=the book contains an excellent discussion of modal logic; his treatment of the race question is badly biased
2. sense_key=discussion%1:10:00:: | definition=an exchange of views on some topic | synonyms=give-and-take, word | examples=we had a good discussion; we had a word or two about it

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context describes "Scientific Discussion" as a formal document within a regulatory report (EPAR) that presents an extended explanation of the scientific basis for recommendations. This aligns with sense 1, which defines discussion as "an extended communication dealing with some particular topic" with the synonym "treatment" and the example of "the book contains an excellent discussion of modal logic." The target usage refers to a structured written treatment of a topic, not an interactive exchange of views as in sense 2.

reasoning_content:
Let me analyze the context to determine which sense of "discussion" is being used.

The sentence reads: "If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR)."

In this context, "Discussion" is being used as a formal document title - "Scientific Discussion" - that is part of a regulatory report (EPAR - European Public Assessment Report). This is a written document that discusses or explains the scientific basis of recommendations.

Let me compare the two senses:

Sense 1: "an extended communication (often interactive) dealing with some particular topic"
- Definition: extended communication, dealing with a topic
- Synonyms: treatment, discourse
- Examples: "the book contains an excellent discussion of modal logic"
- This fits a written, structured explanation of a topic

Sense 2: "an exchange of views on some topic"
- Definition: an exchange of views
- Synonyms: give-and-take, word
- Examples: "we had a good discussion; we had a word or two about it"
- This emphasizes interactive dialogue/conversation

In the context given, "Scientific Discussion" is a formal document that presents information and explanation of the scientific basis. It's not described as an exchange of views or interactive conversation. Rather, it's a formal written treatment/discourse of the scientific reasoning behind the recommendations.

The phrase "an extended communication (often interactive) dealing with some particular topic" from Sense 1, combined with the synonym "treatment" and the example "the book contains an excellent discussion of modal logic" fits better. A "Scientific Discussion" in a regulatory report is an extended communication dealing with scientific topics, similar to how a book contains a discussion/treatment of a logical topic.

The answer should be sense_index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: part
Target surface form: part
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also <t>part</t> of the EPAR). What is Alimta?

Candidate senses:
1. sense_key=part%1:24:00:: | definition=something determined in relation to something that includes it | synonyms=portion, component part, component, constituent | examples=he wanted to feel a part of something bigger than himself; I read a portion of the manuscript
2. sense_key=part%1:06:00:: | definition=something less than the whole of a human artifact | synonyms=portion | examples=the rear part of the house; glue the two parts together
3. sense_key=part%1:17:00:: | definition=a portion of a natural object | synonyms=piece | examples=they analyzed the river into three parts; he needed a piece of granite
4. sense_key=part%1:09:02:: | definition=that which concerns a person with regard to a particular role or situation | examples=it requires vigilance on our part; they resisted every effort on his part
5. sense_key=part%1:15:00:: | definition=the extended spatial location of something | synonyms=region | examples=the farming regions of France; religions in all parts of the world
6. sense_key=part%1:04:01:: | definition=the actions and activities assigned to or required or expected of a person or group | synonyms=function, office, role | examples=the function of a teacher; the government must do its part
7. sense_key=part%1:09:01:: | definition=an actor's portrayal of someone in a play | synonyms=character, role, theatrical role, persona | examples=she played the part of Desdemona
8. sense_key=part%1:21:00:: | definition=assets belonging to or due to or contributed by an individual person or group | synonyms=share, portion, percentage | examples=he wanted his share in cash
9. sense_key=part%1:09:00:: | definition=one of the portions into which something is regarded as divided and which together constitute a whole | synonyms=section, division | examples=the written part of the exam; the finance section of the company
10. sense_key=part%1:08:01:: | definition=a line of scalp that can be seen when sections of hair are combed in opposite directions | synonyms=parting | examples=his part was right in the middle
11. sense_key=part%1:10:00:: | definition=the melody carried by a particular voice or instrument in polyphonic music | synonyms=voice | examples=he tried to sing the tenor part
12. sense_key=part%1:04:03:: | definition=the part played by a person in bringing about a result | synonyms=contribution, share | examples=I am proud of my contribution in advancing the project; they all did their share of the work

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The target word "part" in the phrase "(also part of the EPAR)" refers to the Scientific Discussion as a component or constituent element of the larger European Public Assessment Report. This best matches sense 1, which defines "part" as "something determined in relation to something that includes it" with synonyms like "component part, constituent." The Scientific Discussion is a component constituent of the EPAR document as a whole.

reasoning_content:
Let me analyze the context of the word "part" in the given sentence:

"If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also <t>part</t> of the EPAR)."

The context is saying that the Scientific Discussion is a part of (or component of) the EPAR (European Public Assessment Report).

Let me consider the candidate senses:

1. "part%1:24:00::" - "something determined in relation to something that includes it" - synonyms: portion, component part, component, constituent. This describes something as a component of a larger whole.

2. "part%1:06:00::" - "something less than the whole of a human artifact" - synonyms: portion. Examples: rear part of house, glue two parts together.

3. "part%1:17:00::" - "a portion of a natural object" - synonyms: piece. Examples about analyzing a river.

4. "part%1:09:02::" - "that which concerns a person with regard to a particular role or situation"

5. "part%1:15:00::" - "the extended spatial location of something" - synonyms: region

6. "part%1:04:01::" - "the actions and activities assigned to or required or expected of a person or group" - synonyms: function, office, role

7. "part%1:09:01::" - "an actor's portrayal of someone in a play" - synonyms: character, role, theatrical role, persona

8. "part%1:21:00::" - "assets belonging to or due to or contributed by an individual person or group" - synonyms: share, portion, percentage

9. "part%1:09:00::" - "one of the portions into which something is regarded as divided and which together constitute a whole" - synonyms: section, division. Examples: written part of exam, finance section of company.
10. "part%1:08:01::" - "a line of scalp that can be seen when sections of hair are combed"

11. "part%1:10:00::" - "the melody carried by a particular voice or instrument in polyphonic music"

12. "part%1:04:03::" - "the part played by a person in bringing about a result"

The Scientific Discussion functions as one of the constituent sections within the EPAR document. Between senses 1 and 9, sense 1 is most fitting—it directly captures how the Scientific Discussion is "something determined in relation to something that includes it," emphasizing its role as a component within the larger EPAR structure.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: powder
Target surface form: powder
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a <t>powder</t> that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=powder%1:27:00:: | definition=a solid substance in the form of tiny loose particles; a solid that has been pulverized | synonyms=pulverization, pulverisation
2. sense_key=powder%1:27:01:: | definition=a mixture of potassium nitrate, charcoal, and sulfur in a 75:15:10 ratio which is used in gunnery, time fuses, and fireworks | synonyms=gunpowder
3. sense_key=powder%1:06:01:: | definition=any of various cosmetic or medical preparations dispensed in the form of a pulverized powder

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

The context clearly indicates that Alimta is a medicinal preparation (specifically a pharmaceutical drug containing pemetrexed) that is dispensed in powder form before being dissolved for intravenous infusion. Sense 3 is the best fit because it specifically refers to medical preparations in powder form, which matches the pharmaceutical context of this document discussing a medicinal product.

reasoning_content:
Let me analyze the context to determine which sense of "powder" is being used here.

Context: "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed."

This is describing a pharmaceutical product. Alimta is a medicinal preparation that comes in powder form and is dissolved to make an infusion (intravenous drip).

Let me examine the candidate senses:

1. sense_key=powder%1:27:00:: - "a solid substance in the form of tiny loose particles; a solid that has been pulverized" - This is a general definition of powder as a physical state of matter.

2. sense_key=powder%1:27:01:: - "a mixture of potassium nitrate, charcoal, and sulfur in a 75:15:10 ratio which is used in gunnery, time fuses, and fireworks" - This is specifically gunpowder, which is clearly not relevant here.

3. sense_key=powder%1:06:01:: - "any of various cosmetic or medical preparations dispensed in the form of a pulverized powder" - This is specifically about medicinal (or cosmetic) preparations in powder form.

Given that Alimta is explicitly described as a medicinal preparation (a pharmaceutical drug), sense 3 is the most appropriate. This sense specifically refers to medical preparations dispensed as powder, which is exactly what Alimta is described as in the context.

The answer should be: {"sense_index": 3}


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: solution
Target surface form: solution
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a <t>solution</t> for infusion (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=solution%1:27:00:: | definition=a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution | examples=he used a solution of peroxide and water
2. sense_key=solution%1:10:00:: | definition=a statement that solves a problem or explains how to solve the problem | synonyms=answer, result, resolution, solvent | examples=they were trying to find a peaceful solution; the answers were in the back of the book
3. sense_key=solution%1:09:00:: | definition=a method for solving a problem | examples=the easy solution is to look it up in the handbook
4. sense_key=solution%1:14:00:: | definition=the set of values that give a true statement when substituted into an equation | synonyms=root
5. sense_key=solution%1:04:00:: | definition=the successful action of solving a problem | examples=the solution took three hours

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context describes Alimta powder being "made up into a solution for infusion," which refers to a homogeneous liquid mixture. The pharmaceutical context of dissolving a powder to create a liquid for injection directly matches the definition of a solution as "a homogeneous mixture of two or more substances" (sense 1), as opposed to the problem-solving meanings (senses 2, 3, 5) or the mathematical meaning (sense 4).

reasoning_content:
Let me analyze the context to determine which sense of "solution" is being used.

The context is: "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed."

This is clearly describing a medical/pharmaceutical context where a powder is being mixed with a liquid to create a liquid form for injection/infusion into a vein. This is a homogeneous mixture of substances.

Let me check each sense:

1. sense_key=solution%1:27:00:: - "a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution" with example "he used a solution of peroxide and water" - This is clearly describing a liquid mixture, which matches the context perfectly.

2. sense_key=solution%1:10:00:: - "a statement that solves a problem or explains how to solve the problem" - This is about problem-solving, not about mixtures. Doesn't fit.

3. sense_key=solution%1:09:00:: - "a method for solving a problem" - Again, problem-solving, doesn't fit.

4. sense_key=solution%1:14:00:: - "the set of values that give a true statement when substituted into an equation" - This is a mathematical term, doesn't fit.

5. sense_key=solution%1:04:00:: - "the successful action of solving a problem" - Problem-solving, doesn't fit.

The context clearly refers to a pharmaceutical solution - a liquid mixture created by dissolving or mixing the powder with a liquid medium for medical injection. This is exactly what sense 1 (solution%1:27:00::) describes: "a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution"

The answer should be sense index 1.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: infusion
Target surface form: infusion
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for <t>infusion</t> (drip into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=infusion%1:27:00:: | definition=a solution obtained by steeping or soaking a substance (usually in water) | synonyms=extract
2. sense_key=infusion%1:22:00:: | definition=the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)
3. sense_key=infusion%1:04:00:: | definition=(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)
4. sense_key=infusion%1:04:01:: | definition=the act of infusing or introducing a certain modifying element or quality | examples=the team's continued success is attributable to a steady infusion of new talent

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

The context explicitly describes "infusion" as a "drip into a vein," which directly corresponds to the medical sense of intravenous administration of a fluid or drug. This is the passive introduction of a substance into a vein by gravitational force, as defined in sense 3.

reasoning_content:
Let me analyze the context carefully. The target word is "infusion" in the phrase:

"Alimta is a powder that is made up into a solution for infusion (drip into a vein)."

The context provides a parenthetical explanation: "(drip into a vein)" which is very explicit about what type of infusion is being discussed.

Let me review the candidate senses:

1. sense_key=infusion%1:27:00:: - "a solution obtained by steeping or soaking a substance (usually in water)" - This is about a solution that results from steeping/soaking. Not the right sense here.

2. sense_key=infusion%1:22:00:: - "the process of extracting certain active properties (as a drug from a plant) by steeping or soaking (usually in water)" - This is about the extraction process. Not relevant here.

3. sense_key=infusion%1:04:00:: - "(medicine) the passive introduction of a substance (a fluid or drug or electrolyte) into a vein or between tissues (as by gravitational force)" - This matches perfectly! The context says "drip into a vein" which is exactly what this medical sense describes. A drip into a vein is the introduction of a substance into a vein by gravitational force.

4. sense_key=infusion%1:04:01:: - "the act of infusing or introducing a certain modifying element or quality" with examples about introducing new talent - This is a metaphorical/abstract sense about introducing qualities or elements, not about medical administration.

The context clearly indicates a medical/pharmaceutical context (Alimta is a medicine, and the parenthetical "drip into a vein" makes it clear we're talking about intravenous administration).

The answer is sense 3, which is the medical sense about introducing a substance into a vein.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: drip
Target surface form: drip
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (<t>drip</t> into a vein). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=drip%2:38:00:: | definition=fall in drops | examples=Water is dripping from the faucet
2. sense_key=drip%2:35:10:: | definition=let or cause to fall in drops | synonyms=dribble, drop | examples=dribble oil into the mixture

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context describes how a medicine solution is administered "for infusion (drip into a vein)." Here, "drip" refers to the liquid falling in drops into the vein, which corresponds to sense 1 (fall in drops). This is the intransitive sense describing the action of the solution itself, rather than an agent deliberately causing the drops.

reasoning_content:
Let me analyze the context to determine which sense of "drip" is being used.

The target word appears in this phrase: "a solution for infusion (drip into a vein)"

This is describing how a medicine is administered. The context indicates that "drip" here refers to the act of slowly administering a liquid into a vein via an intravenous infusion.

Let me examine the two candidate senses:

1. sense_key=drip%2:38:00:: | definition=fall in drops | examples=Water is dripping from the faucet
   - This is the intransitive sense where liquid falls in drops naturally/passively

2. sense_key=drip%2:35:10:: | definition=let or cause to fall in drops | synonyms=dribble, drop | examples=dribble oil into the mixture
   - This is the transitive sense where something causes liquid to fall in drops

In the medical context, "drip into a vein" is describing a controlled, intentional process where a solution is made to slowly fall/flow into a vein. This is an active process - the medical professionals are causing the solution to drip into the vein.

The phrase "drip into a vein" suggests the agent is causing the dripping action - this aligns with sense 2 (let or cause to fall in drops), which is the transitive sense.

Actually, wait. Let me reconsider. In medical terminology, an "IV drip" is often just called a "drip." The word here might be used as a noun referring to the apparatus or the procedure itself. But looking at the glosses:

Sense 1: "fall in drops" - intransitive, the liquid itself falls
Sense 2: "let or cause to fall in drops" - transitive, someone/something causes it to fall

In the context "drip into a vein", this is describing the action of the solution being administered. It's the solution dripping (sense 1 - the literal action of falling in drops), but in a controlled medical setting.
The core meaning here is simply the liquid falling in drops into the vein, which matches sense 1. The medical context doesn't change the fundamental action being described—it's the solution itself that's falling in drops.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: vein
Target surface form: vein
Context:
This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a <t>vein</t>). It contains the active substance pemetrexed.

Candidate senses:
1. sense_key=vein%1:08:00:: | definition=a blood vessel that carries blood from the capillaries toward the heart | synonyms=vena, venous blood vessel | examples=all veins except the pulmonary vein carry unaerated blood
2. sense_key=vein%1:10:00:: | definition=a distinctive style or manner | examples=he continued in this vein for several minutes
3. sense_key=vein%1:20:00:: | definition=any of the vascular bundles or ribs that form the branching framework of conducting and supporting tissues in a leaf or other plant organ | synonyms=nervure
4. sense_key=vein%1:17:00:: | definition=a layer of ore between layers of rock | synonyms=mineral vein
5. sense_key=vein%1:05:00:: | definition=one of the horny ribs that stiffen and support the wing of an insect | synonyms=nervure

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
{"sense_index": 1}

The context clearly refers to an intravenous infusion procedure for administering medication. The phrase "drip into a vein" describes injecting a solution directly into a blood vessel. Sense 1, which defines vein as "a blood vessel that carries blood from the capillaries toward the heart," is the correct anatomical meaning for this medical context.

reasoning_content:
Let me analyze the context to determine the correct sense of "vein" in this medical document.

The context states: "Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed."

This is clearly describing a medical infusion procedure where a medication is dripped into a vein. The term "drip into a vein" refers to intravenous administration.

Let me evaluate each candidate sense:

1. sense_key=vein%1:08:00:: | definition=a blood vessel that carries blood from the capillaries toward the heart
   - This is the correct anatomical meaning. A vein is a blood vessel, and this describes exactly what would receive an intravenous infusion.

2. sense_key=vein%1:10:00:: | definition=a distinctive style or manner
   - This doesn't fit the context at all. This is an idiomatic use (like "in a humorous vein").

3. sense_key=vein%1:20:00:: | definition=any of the vascular bundles or ribs that form the branching framework of conducting and supporting tissues in a leaf or other plant organ
   - This refers to plant structures, not relevant to medical infusion.

4. sense_key=vein%1:17:00:: | definition=a layer of ore between layers of rock
   - This is about mining/geology, not relevant.

5. sense_key=vein%1:05:00:: | definition=one of the horny ribs that stiffen and support the wing of an insect
   - This is about insect anatomy, not relevant.

The answer is clearly sense 1, which is the anatomical sense of a blood vessel.

The medication is being administered through intravenous infusion, which requires understanding veins as the circulatory structures that receive such treatment.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: contain
Target surface form: contains
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It <t>contains</t> the active substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=contain%2:42:00:: | definition=include or contain; have as a component | synonyms=incorporate, comprise | examples=A totally new idea is comprised in this paper; The record contains many old songs from the 1930's
2. sense_key=contain%2:42:13:: | definition=contain or hold; have within | synonyms=hold, bear, carry | examples=The jar carries wine; The canteen holds fresh water
3. sense_key=contain%2:41:00:: | definition=lessen the intensity of; temper; hold in restraint; hold or keep within limits | synonyms=control, hold in, hold, check, curb, moderate | examples=moderate your alcohol intake; hold your tongue
4. sense_key=contain%2:42:06:: | definition=be divisible by | examples=24 contains 6
5. sense_key=contain%2:42:14:: | definition=be capable of holding or containing | synonyms=take, hold | examples=This box won't take all the items; The flask holds one gallon
6. sense_key=contain%2:33:00:: | definition=hold back, as of a danger or an enemy; check the expansion or influence of | synonyms=check, turn back, arrest, stop, hold back | examples=Arrest the downward trend; Check the growth of communism in South East Asia

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The sentence states that Alimta "contains the active substance pemetrexed," meaning the solution has pemetrexed as a component. This matches sense 1, which defines contain as "include or contain; have as a component." The example "The record contains many old songs from the 1930's" is structurally parallel to the target sentence, describing what components or substances are part of something.

reasoning_content:
The target word is "contains" in the sentence: "It contains the active substance pemetrexed."

This is about a medicine (Alimta) being made up into a solution, and the statement describes what active substance it contains.

Let me analyze each sense:

1. sense_key=contain%2:42:00:: - "include or contain; have as a component" with examples like "The record contains many old songs from the 1930's" - This seems very relevant. It's about having something as a component.

2. sense_key=contain%2:42:13:: - "contain or hold; have within" with examples like "The jar carries wine; The canteen holds fresh water" - This is also about holding something within, which fits.

3. sense_key=contain%2:41:00:: - "lessen the intensity of; temper; hold in restraint" - This is about controlling or restraining, which doesn't fit the context.

4. sense_key=contain%2:42:06:: - "be divisible by" with example "24 contains 6" - This is a mathematical sense, doesn't fit.

5. sense_key=contain%2:42:14:: - "be capable of holding or containing" - This is about capacity, not about what the thing actually contains.

6. sense_key=contain%2:33:00:: - "hold back, as of a danger or an enemy" - This is about restraining/checking, doesn't fit.

The sentence says "It contains the active substance pemetrexed" - meaning the solution HAS the active substance as part of its composition.

Sense 1 seems most appropriate: "include or contain; have as a component" - this fits the meaning where Alimta (the solution) has pemetrexed as a component/part of it.

Sense 2 could also work, but sense 1 seems more precise with "have as a component" which directly matches the context.
Sense 1 is the best fit here.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: active
Target surface form: active
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the <t>active</t> substance pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=active%3:00:02:: | definition=tending to become more severe or wider in scope | examples=active tuberculosis
2. sense_key=active%5:00:00:operational:00 | definition=engaged in or ready for military or naval operations | synonyms=combat-ready, fighting | examples=on active duty; the platoon is combat-ready
3. sense_key=active%3:00:03:: | definition=disposed to take action or effectuate change | examples=a director who takes an active interest in corporate operations; an active antagonism
4. sense_key=active%5:00:00:involved:00 | definition=taking part in an activity | synonyms=participating | examples=an active member of the club; he was politically active
5. sense_key=active%3:00:01:: | definition=characterized by energetic activity | examples=an active toddler; active as a gazelle
6. sense_key=active%3:00:07:: | definition=exerting influence or producing a change or effect | examples=an active ingredient
7. sense_key=active%3:00:06:: | definition=full of activity or engaged in continuous activity | examples=an active seaport; an active bond market
8. sense_key=active%5:00:00:existent:00 | definition=in operation | synonyms=alive | examples=keep hope alive; the tradition was still alive
9. sense_key=active%3:00:10:: | definition=(of the sun) characterized by an increased occurrence of sunspots and flares and radio emissions
10. sense_key=active%3:00:09:: | definition=expressing that the subject of the sentence has the semantic function of actor: | examples=Hemingway favors active constructions
11. sense_key=active%3:00:00:: | definition=(used of verbs (e.g. `to run') and participial adjectives (e.g. `running' in `running water')) expressing action rather than a state of being | synonyms=dynamic
12. sense_key=active%3:00:05:: | definition=(of e.g. volcanos) capable of erupting
13. sense_key=active%3:00:04:: | definition=(of e.g. volcanos) erupting or liable to erupt | examples=active volcanos
14. sense_key=active%3:00:08:: | definition=engaged in full-time work | examples=active duty; though past retirement age he is still active in his profession

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 6}
```

The context describes "active substance pemetrexed" in a pharmaceutical document. Sense 6 defines "active" as "exerting influence or producing a change or effect" with the example "an active ingredient" - which directly parallels the pharmaceutical usage of "active substance" to mean the component in a medicine that produces the therapeutic effect.

reasoning_content:
Let me analyze the context. The sentence is:

"It contains the <t>active</t> substance pemetrexed."

In pharmaceutical/medical context, "active substance" refers to the substance in a medication that has a pharmacological effect or produces the desired therapeutic action. This is a standard pharmaceutical term.

Looking at the candidate senses:

1. sense_key=active%3:00:02:: | definition=tending to become more severe or wider in scope | examples=active tuberculosis
   - This is more about the disease state, not about substances

2. sense_key=active%5:00:00:operational:00 | definition=engaged in or ready for military or naval operations
   - Not relevant

3. sense_key=active%3:00:03:: | definition=disposed to take action or effectuate change
   - About agents taking action, not relevant

4. sense_key=active%5:00:00:involved:00 | definition=taking part in an activity
   - Not relevant

5. sense_key=active%3:00:01:: | definition=characterized by energetic activity
   - Not relevant

6. sense_key=active%3:00:07:: | definition=exerting influence or producing a change or effect | examples=an active ingredient
   - THIS! "an active ingredient" - this is exactly what an active substance is in pharmaceuticals. A substance that exerts influence or produces a change/effect.

7. sense_key=active%3:00:06:: | definition=full of activity or engaged in continuous activity
   - Not relevant

8. sense_key=active%5:00:00:existent:00 | definition=in operation
   - Could be relevant but less specific

9. sense_key=active%3:00:10:: | definition=(of the sun)...
   - Not relevant

10. sense_key=active%3:00:09:: | definition=expressing grammatical voice
   - Not relevant

11. sense_key=active%3:00:00:: | definition=used of verbs...
   - Not relevant

The remaining senses don't apply here. Sense 6 is the clear winner—it directly matches the pharmaceutical meaning where "active" describes something that produces a therapeutic effect, just like the example "active ingredient" demonstrates.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: substance
Target surface form: substance
Context:
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, to reach their recommendations on how to use the medicine. If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active <t>substance</t> pemetrexed. What is Alimta used for?

Candidate senses:
1. sense_key=substance%1:03:00:: | definition=the real physical matter of which a person or thing consists | examples=DNA is the substance of our genes
2. sense_key=substance%1:09:01:: | definition=the choicest or most essential or most vital part of some idea or experience | synonyms=kernel, core, center, centre, essence, gist | examples=the gist of the prosecutor's argument; the heart and soul of the Republican Party
3. sense_key=substance%1:09:00:: | definition=the idea that is intended | synonyms=meaning | examples=What is the meaning of this proverb?
4. sense_key=substance%1:27:00:: | definition=material of a particular kind or constitution | examples=the immune response recognizes invading substances
5. sense_key=substance%1:21:00:: | definition=considerable capital (wealth or income) | synonyms=means | examples=he is a man of means
6. sense_key=substance%1:10:00:: | definition=what a communication that is about something is about | synonyms=message, content, subject matter
7. sense_key=substance%1:03:01:: | definition=a particular kind or species of matter with uniform properties | examples=shigella is one of the most toxic substances known to man

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 7}
```

The context describes pemetrexed as "the active substance" in Alimta, referring to a specific pharmaceutical chemical compound. Sense 7 ("a particular kind or species of matter with uniform properties") best fits this usage, as it describes a distinct material with defined chemical properties, similar to the example "shigella is one of the most toxic substances known to man." The active substance in a medicine is precisely a particular kind of matter with uniform pharmaceutical properties.

reasoning_content:
Let me analyze the context carefully. The sentence is: "It contains the active substance pemetrexed."

The word "substance" here is referring to pemetrexed, which is a chemical/pharmaceutical compound - a material or chemical matter.

Let me evaluate each candidate sense:

1. sense_key=substance%1:03:00:: "the real physical matter of which a person or thing consists" - Examples include DNA is the substance of our genes. This is about physical matter making up something.

2. sense_key=substance%1:09:01:: "the choicest or most essential or most vital part of some idea or experience" - About kernel, core, essence. Not applicable here.

3. sense_key=substance%1:09:00:: "the idea that is intended" - About meaning. Not applicable.

4. sense_key=substance%1:27:00:: "material of a particular kind or constitution" - Examples: "the immune response recognizes invading substances". This is about a particular kind of material. This seems very relevant as pemetrexed is a particular kind of chemical material.

5. sense_key=substance%1:21:00:: "considerable capital (wealth or income)" - Not applicable, this is about money/wealth.

6. sense_key=substance%1:10:00:: "what a communication that is about something is about" - Not applicable, this is about the subject matter of communication.

7. sense_key=substance%1:03:01:: "a particular kind or species of matter with uniform properties" - Examples: "shigella is one of the most toxic substances known to man". This is about a particular kind of matter with specific properties.

In the context "It contains the active substance pemetrexed," we're talking about pemetrexed as a particular chemical/pharmaceutical material.

The key question is between senses 1, 4, and 7:
- Sense 1 is about physical matter that things consist of
- Sense 4 describes material with specific constitution, illustrated by immune system examples recognizing invading substances in biological contexts
- Sense 7 refers to distinct types of matter with defined properties, exemplified by references to toxic substances

Given the pharmaceutical setting where pemetrexed is identified as a specific chemical compound, sense 7 provides the most precise fit—it captures the notion of a distinct substance with particular properties rather than just generic physical matter.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you need more information about your medical condition or your treatment, read the Package Leaflet (also part of the EPAR) or contact your doctor or pharmacist. If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta <t>used</t> for? Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos).

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context "What is Alimta used for?" asks about the purpose or application of the medication. This matches sense 1, which defines "use" as putting something into service for a particular purpose. The synonyms "employ" and "apply" and the structure of the question align with employing Alimta to treat cancer types, rather than consuming it, manipulating it for advantage, or describing a habitual past action.

reasoning_content:
Let me analyze the context for the word "used" in the sentence: "What is Alimta <t>used</t> for?"

This is asking what purpose or function Alimta serves - specifically what it's used to treat or for what purpose it's used.

Let me examine each candidate sense:

1. sense_key=use%2:34:01:: - "put into service; make work or employ for a particular purpose or for its inherent or natural purpose" with synonyms utilize, utilise, apply, employ. Examples: "use your head!; we only use Spanish at home"
   This fits well - Alimta is employed/used for the purpose of treating cancer.

2. sense_key=use%2:34:02:: - "take or consume (regularly or habitually)" with example "She uses drugs rarely"
   This doesn't fit - we're not talking about consuming or habituating to Alimta regularly.

3. sense_key=use%2:34:00:: - "use up, consume fully" with synonyms expend
   This doesn't fit - the sentence isn't about consuming the drug but about its purpose/application.

4. sense_key=use%2:41:14:: - "seek or achieve an end by using to one's advantage"
   This has a manipulative connotation that doesn't fit here.

5. sense_key=use%2:41:04:: - "avail oneself to" with examples "apply a principle; practice a religion"
   This could fit, but it's about applying something to oneself, not quite the same as describing what something is used FOR.

6. sense_key=use%2:41:03:: - "habitually do something (use only in the past tense)"
   This doesn't fit - the example is "She used to call her mother" which has a different temporal meaning.

Sense 1 is the clear match here. The question asks what purpose Alimta serves, which directly corresponds to employing something for a particular purpose.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: use
Target surface form: used
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is <t>used</t> to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
6. sense_key=use%2:41:03:: | definition=habitually do something (use only in the past tense) | examples=She used to call her mother every week but now she calls only occasionally; I used to get sick when I ate in that dining hall

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The target word "used" in the context "Alimta is used to treat two types of cancer" employs the sense of "put into service; make work or employ for a particular purpose." This is describing the application of a pharmaceutical product for its intended medical purpose, which aligns with the synonyms "utilize" and "employ" in sense 1. The other senses (consumption, expending, manipulation, habituality) do not fit this descriptive context about a drug's therapeutic application.

reasoning_content:
Let me analyze the context and identify which sense of "used" is being employed.

The target sentence is: "Alimta is <t>used</t> to treat two types of cancer: pleural mesothelioma..."

The context is discussing what Alimta is and what it's used for - specifically as a medical treatment for cancer. It's describing a pharmaceutical product and its application.

Let me examine each candidate sense:

1. sense_key=use%2:34:01:: | definition=put into service; make work or employ for a particular purpose or for its inherent or natural purpose | synonyms=utilize, utilise, apply, employ | examples=use your head!; we only use Spanish at home
   - This fits: "used to treat cancer" = "put into service to treat cancer" = employ for a particular purpose

2. sense_key=use%2:34:02:: | definition=take or consume (regularly or habitually) | synonyms=habituate | examples=She uses drugs rarely
   - This doesn't fit. The sentence doesn't mean that Alimta is consumed or taken habitually.

3. sense_key=use%2:34:00:: | definition=use up, consume fully | synonyms=expend | examples=The legislature expended its time on school questions
   - This doesn't fit. This is about consuming or expending something.

4. sense_key=use%2:41:14:: | definition=seek or achieve an end by using to one's advantage | examples=She uses her influential friends to get jobs; The president's wife used her good connections
   - This doesn't fit. This implies manipulation or using someone for advantage, which isn't the case here.

5. sense_key=use%2:41:04:: | definition=avail oneself to | synonyms=practice, apply | examples=apply a principle; practice a religion
   - This could work, but it's more about applying principles or practicing.

The remaining senses don't align either. The habitual past tense construction in sense 6 doesn't match the passive voice structure here, and the other options involve either consumption or manipulation that aren't relevant to describing a medication's therapeutic application. The first sense clearly captures the intended meaning—Alimta is employed as a treatment tool for cancer.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: treat
Target surface form: treat
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to <t>treat</t> two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=treat%2:41:00:: | definition=interact in a certain way | synonyms=handle, do by | examples=Do right by her; Treat him with caution, please
2. sense_key=treat%2:30:01:: | definition=subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition | synonyms=process | examples=process cheese; process hair
3. sense_key=treat%2:29:00:: | definition=provide treatment for | synonyms=care for | examples=The doctor treated my broken leg; The nurses cared for the bomb victims
4. sense_key=treat%2:32:00:: | definition=act on verbally or in some form of artistic expression | synonyms=cover, handle, plow, deal, address | examples=This book deals with incest; The course covered all of Western Civilization
5. sense_key=treat%2:40:00:: | definition=provide with a gift or entertainment | examples=Grandmother always treated us to the circus; I like to treat myself to a day at a spa when I am depressed
6. sense_key=treat%2:34:00:: | definition=provide with choice or abundant food or drink | synonyms=regale | examples=Don't worry about the expensive wine--I'm treating; She treated her houseguests with good food every night
7. sense_key=treat%2:32:03:: | definition=engage in negotiations in order to reach an agreement | examples=they had to treat with the King
8. sense_key=treat%2:31:00:: | definition=regard or consider in a specific way | examples=I treated his advances as a joke

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 3}
```

The context clearly indicates medical treatment: "Alimta is used to treat two types of cancer." Sense 3 ("provide treatment for") is the appropriate sense, as it refers to providing medical care or treatment for a disease or condition, with examples like "The doctor treated my broken leg." This aligns perfectly with the usage of a pharmaceutical treatment for cancer.

reasoning_content:
The target word is "treat" in the context: "Alimta is used to treat two types of cancer: pleural mesothelioma..."

Let me analyze each sense:

1. "interact in a certain way" - Not applicable here. This is about how you interact with someone/something in a behavioral sense.

2. "subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition" - This is about processing or treating something to prepare it. Example: "process cheese; process hair". This is about processing materials.

3. "provide treatment for" - This means to give medical treatment or care. Examples: "The doctor treated my broken leg; The nurses cared for the bomb victims". This is clearly about providing medical care/treatment.

4. "act on verbally or in some form of artistic expression" - This is about discussing or dealing with a topic. Not applicable.

5. "provide with a gift or entertainment" - This is about giving someone a treat as a reward. Not applicable.

6. "provide with choice or abundant food or drink" - This is about serving food/drink generously. Not applicable.

7. "engage in negotiations in order to reach an agreement" - Not applicable.

8. "regard or consider in a specific way" - Not applicable.

In the context of "Alimta is used to treat two types of cancer", we're talking about using a medicine to provide medical treatment for cancer. This clearly aligns with sense 3: "provide treatment for" with the medical meaning.

The answer should be sense 3.


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: type
Target surface form: types
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two <t>types</t> of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=type%1:09:00:: | definition=a subdivision of a particular kind of thing | examples=what type of sculpture do you prefer?
2. sense_key=type%1:18:00:: | definition=a person of a specified kind (usually with many eccentricities) | synonyms=character, eccentric, case | examples=a real character; a strange character
3. sense_key=type%1:14:01:: | definition=(biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. sense_key=type%1:10:01:: | definition=printed characters | examples=small type is hard to read
5. sense_key=type%1:10:00:: | definition=all of the tokens of the same symbol | examples=the word `element' contains five different types of character
6. sense_key=type%1:06:00:: | definition=a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper | examples=he dropped a case of type, so they made him pick them up

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The word "types" in this context refers to different categories or kinds of cancer. The phrase "two types of cancer" means "two kinds/categories of cancer." This matches sense 1: "a subdivision of a particular kind of thing," which is directly comparable to the example "what type of sculpture do you prefer?"

reasoning_content:
Let me analyze the context where "types" appears in the sentence:

"Alimta is used to treat two types of cancer: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos)."

The word "types" here refers to different kinds/categories of cancer. It's used in the sense of "kinds" or "varieties" of cancer.

Let me look at the candidate senses:

1. "a subdivision of a particular kind of thing" - This is about categorizing things into different types/kinds
2. "a person of a specified kind (usually with many eccentricities)" - This is about a person, not relevant
3. "(biology) the taxonomic group whose characteristics are used to define the next higher taxon" - This is a specific biological term
4. "printed characters" - This is about typography/printing
5. "all of the tokens of the same symbol" - This is about linguistic/symbolic tokens
6. "a small metal block bearing a raised character on one end" - This is about printing press type

The context is clearly talking about different categories/kinds of cancer. The most appropriate sense is sense 1: "a subdivision of a particular kind of thing" with the example "what type of sculpture do you prefer?" - this directly parallels the usage of "types of cancer."

The answer should be sense_index: 1


[System] You are an English linguist performing fine-grained Word Sense Disambiguation. WordNet glosses are schematic. Use the sentence context, the examples, and the synonyms to choose the best indexed sense. Do not hedge. Choose the single best indexed sense.

[User]
Target lemma: cancer
Target surface form: cancer
Context:
If you want more information on the basis of the CHMP recommendations, read the Scientific Discussion (also part of the EPAR). What is Alimta? Alimta is a powder that is made up into a solution for infusion (drip into a vein). It contains the active substance pemetrexed. What is Alimta used for? Alimta is used to treat two types of <t>cancer</t>: pleural mesothelioma (cancer of the lining of the lungs that is usually caused by exposure to asbestos). Alimta is used together with cisplatin (another anticancer medicine) when the cancer is unresectable (cannot be removed by surgery alone) and malignant (has spread, or is likely to spread easily, to other parts of the body), in patients who have not received chemotherapy (medicines for cancer) before advanced or metastatic non-small cell lung cancer that is not affecting the squamous cells.

Candidate senses:
1. sense_key=cancer%1:26:00:: | definition=any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream | synonyms=malignant neoplastic disease
2. sense_key=cancer%1:18:00:: | definition=(astrology) a person who is born while the sun is in Cancer | synonyms=Crab
3. sense_key=cancer%1:17:00:: | definition=a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
4. sense_key=cancer%1:15:00:: | definition=the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 | synonyms=Cancer the Crab, Crab
5. sense_key=cancer%1:05:00:: | definition=type genus of the family Cancridae | synonyms=genus Cancer

Instructions:
1. Choose the single best indexed sense for the target word in context.
2. WordNet glosses are schematic; use the context, synonyms, and examples together.
3. Do not answer with a WordNet sense key.
4. Return only a JSON object exactly like {"sense_index": 3}.

raw_output:
```json
{"sense_index": 1}
```

The context clearly indicates that "cancer" refers to a medical condition - specifically malignant tumors or growths that spread to other parts of the body. The passage discusses cancer treatment with an anticancer medicine, mentions it can be unresectable, and describes both pleural mesothelioma and non-small cell lung cancer as types of cancer. This matches sense 1, which defines cancer as "any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream."

reasoning_content:
Let me analyze the context to determine the correct sense of "cancer" in this passage.

The passage is about a pharmaceutical product called Alimta used to treat two types of cancer:
1. Pleural mesothelioma (cancer of the lining of the lungs)
2. Advanced or metastatic non-small cell lung cancer

The context clearly indicates that "cancer" refers to a medical condition - specifically malignant tumors that can spread to other parts of the body.

Let me look at the candidate senses:

1. sense_key=cancer%1:26:00:: - "any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream" with synonyms "malignant neoplastic disease"
   - This is the medical/biological definition of cancer as a disease

2. sense_key=cancer%1:18:00:: - "(astrology) a person who is born while the sun is in Cancer"
   - This is about astrology, clearly not relevant

3. sense_key=cancer%1:17:00:: - "a small zodiacal constellation in the northern hemisphere; between Leo and Gemini"
   - This is about the constellation, not relevant

4. sense_key=cancer%1:15:00:: - "the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22"
   - This is about astrology/zodiac, not relevant

5. sense_key=cancer%1:05:00:: - "type genus of the family Cancridae"
   - This is about a genus of crabs, not relevant

The correct sense is clearly #1, which refers to the medical condition of malignant tumors. The context explicitly discusses cancer as a disease that needs treatment with anticancer medicine, it spreads to other parts of the body, and can be unresectable or metastatic. This matches perfectly with sense 1.
The answer is sense index 1.